<?xml version="1.0" encoding="UTF-8"?><ns2:project xmlns:ns1="http://gtr.rcuk.ac.uk/gtr/api" xmlns:ns2="http://gtr.rcuk.ac.uk/gtr/api/project" xmlns:ns3="http://gtr.rcuk.ac.uk/gtr/api/fund" xmlns:ns4="http://gtr.rcuk.ac.uk/gtr/api/person" xmlns:ns5="http://gtr.rcuk.ac.uk/gtr/api/project/outcome" xmlns:ns6="http://gtr.rcuk.ac.uk/gtr/api/organisation" ns1:created="2026-07-08T08:44:08Z" ns1:href="http://gtr.ukri.org/gtr/api/projects/14BD76A4-ED1F-4279-8BAB-3F8F1E8FFA28" ns1:id="14BD76A4-ED1F-4279-8BAB-3F8F1E8FFA28"><ns1:links><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/persons/0AAD144D-0A95-4A3C-8F8D-AB52C54BE708" ns1:rel="PM_PER"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/C16F4700-409B-40D6-917A-48A9EE48BEB8" ns1:rel="LEAD_ORG"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/C16F4700-409B-40D6-917A-48A9EE48BEB8" ns1:rel="PARTICIPANT_ORG"/><ns1:link ns1:end="2020-08-30T23:00:00Z" ns1:href="http://gtr.ukri.org/gtr/api/funds/65EF5ED3-7968-4C2B-AEB5-9D41C9011462" ns1:rel="FUND" ns1:start="2020-05-31T23:00:00Z"/></ns1:links><ns2:identifiers><ns2:identifier ns2:type="RCUK">69299</ns2:identifier></ns2:identifiers><ns2:title>Re-purposing, environmentally damaging HFC cryogenic chillers to environmentally inert natural refrigerants, for process chilling in the post Covid-19 pharmaceutical industry.</ns2:title><ns2:status>Closed</ns2:status><ns2:grantCategory>Feasibility Studies</ns2:grantCategory><ns2:leadFunder>Innovate UK</ns2:leadFunder><ns2:abstractText>Over the next few months, UK pharmaceutical companies and institutes will need to develop anti-viral drugs to help overcome symptoms and vaccines to protect against and help combat the devastating effect of the COVID-19 virus.

Novel manufacturing techniques such as continuous processing, together with the safe low-temperature storage of vaccines will be required. These processes require temperatures between -50 and -80&amp;deg;C to operate correctly.

Currently, mechanical compressor-based low-temperature refrigeration systems use high cost \[&amp;pound;690/kg\] environmentally damaging HFC refrigerant gases. These gases under the UK-EU and UN climate change policies are legislated to be phased out over the next 10 years.

Likido currently manufactures low carbon, high-temperature industrial heat pumps that use a non-toxic, non-?ammable, environmentally inert, CFC/HFC free &amp;quot;natural working ?uid&amp;quot;. Using Likido's experience in natural refrigerant technology and its unique two-stage compressors design, Likido over the next 3 months plan to fast track the manufacturing of a new range Cryochillers which will use HFC free &amp;quot;natural refrigerant gases that can operate down to -70&amp;deg;C and have global warming potential \[GWP\] of less than 50\.

This new innovation will ensure safe production and storage of medicines and vaccines at low temperatures and keep the UK's government commitment to climate change legislation.</ns2:abstractText></ns2:project>