710238Magnetic tissue marker for localising breast cancersClosedGRD Proof of ConceptInnovate UKAround the world the increasing prevalence of breast cancer screening means that cancers are more often being detected at an early stage when they are only visible under imaging and cannot otherwise be located. In these cases, the surgeon requires a guide marker to locate the tumour to be removed. The current ‘gold standard’ for removing such 'non-palpable' tumours is wire-guided localisation (WGL), where the radiologist places a guide wire at the lesion site via imaging (Ultrasound/MRI/X-ray), and the surgeon removes the tissue around the wire. While WGL is useful, it presents some challenges: The wire is only inserted on the day of surgery, so scheduling between radiology and surgery can be challenging; the wire can become dislodged or move, decreasing accuracy in the removal of cancerous tissue; and insertion can be painful for patients. Endomagnetics has identified an opportunity for a new localisation technique based on its magnetic detection technology, which will overcome the drawbacks of the current approach and offer improvements in efficiency, and cost as well as reducing the number of procedures and the inconvenience for patients. This TSB funded project will demonstrate the first proof of concept for this new marker technique.