<?xml version="1.0" encoding="UTF-8"?><ns2:project xmlns:ns1="http://gtr.rcuk.ac.uk/gtr/api" xmlns:ns2="http://gtr.rcuk.ac.uk/gtr/api/project" xmlns:ns3="http://gtr.rcuk.ac.uk/gtr/api/fund" xmlns:ns4="http://gtr.rcuk.ac.uk/gtr/api/person" xmlns:ns5="http://gtr.rcuk.ac.uk/gtr/api/project/outcome" xmlns:ns6="http://gtr.rcuk.ac.uk/gtr/api/organisation" ns1:created="2026-06-22T07:57:45Z" ns1:href="http://gtr.ukri.org/gtr/api/projects/A3664AF8-ED06-4290-88FB-71E21819DB73" ns1:id="A3664AF8-ED06-4290-88FB-71E21819DB73"><ns1:links><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/persons/BCFE601B-ED28-4366-95FF-FCB81DAA862C" ns1:rel="PM_PER"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/69727093-183A-4269-AEDF-61F83018F241" ns1:rel="LEAD_ORG"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/69727093-183A-4269-AEDF-61F83018F241" ns1:rel="PARTICIPANT_ORG"/><ns1:link ns1:end="2020-11-30T00:00:00Z" ns1:href="http://gtr.ukri.org/gtr/api/funds/228F96DA-C682-4256-A7C5-020F054A9E57" ns1:rel="FUND" ns1:start="2020-05-31T23:00:00Z"/></ns1:links><ns2:identifiers><ns2:identifier ns2:type="RCUK">63041</ns2:identifier></ns2:identifiers><ns2:title>Care home BiPAP breathing aid for early stage intervention</ns2:title><ns2:status>Closed</ns2:status><ns2:grantCategory>Feasibility Studies</ns2:grantCategory><ns2:leadFunder>Innovate UK</ns2:leadFunder><ns2:abstractText>A significant number of COVID-related deaths in the UK, EU and worldwide occur in care homes where elderly residents contract the disease but cannot be hospitalised due to a lack of capacity or poor expected clinical outcomes from later stage medical interventions such as invasive ventilation. Recent studies have shown that the application of bi-level positive airway pressure (BiPAP) respiratory support for patients at an early stage of influenza-type respiratory diseases reduces progression to ARDS for a significant proportion of patients.

A BiPAP device is similar to a user-operated continuous positive airway pressure device (e.g. a sleep apnea machine) but provides two pressure levels to reduce breathing effort and assist exhalation.

The objective of this project is to create a low cost BiPAP device suitable for deployment in UK care homes to reduce mortality due to COVID-19 infections during 2020, and to provide an effective early stage intervention to reduce mortality in subsequent annual flu seasons.</ns2:abstractText></ns2:project>