<?xml version="1.0" encoding="UTF-8"?><ns2:project xmlns:ns1="http://gtr.rcuk.ac.uk/gtr/api" xmlns:ns2="http://gtr.rcuk.ac.uk/gtr/api/project" xmlns:ns3="http://gtr.rcuk.ac.uk/gtr/api/fund" xmlns:ns4="http://gtr.rcuk.ac.uk/gtr/api/person" xmlns:ns5="http://gtr.rcuk.ac.uk/gtr/api/project/outcome" xmlns:ns6="http://gtr.rcuk.ac.uk/gtr/api/organisation" ns1:created="2026-06-03T15:52:43Z" ns1:href="http://gtr.ukri.org/gtr/api/projects/CEEDCF94-A1AF-4A49-82EA-268A7D7F23ED" ns1:id="CEEDCF94-A1AF-4A49-82EA-268A7D7F23ED"><ns1:links><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/persons/C660C6B2-A8D6-4FD0-8CA5-37281F0E29BE" ns1:rel="PM_PER"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/B574D77E-01B6-4DCF-A6FD-FECD16981D1A" ns1:rel="LEAD_ORG"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/B574D77E-01B6-4DCF-A6FD-FECD16981D1A" ns1:rel="PARTICIPANT_ORG"/><ns1:link ns1:end="2020-11-30T00:00:00Z" ns1:href="http://gtr.ukri.org/gtr/api/funds/887EC29D-02D6-42F8-A936-2849018F2828" ns1:rel="FUND" ns1:start="2019-01-01T00:00:00Z"/></ns1:links><ns2:identifiers><ns2:identifier ns2:type="RCUK">105077</ns2:identifier></ns2:identifiers><ns2:title>Discovery of next generation HER2 antibodies for the treatment of cancer</ns2:title><ns2:status>Closed</ns2:status><ns2:grantCategory>Feasibility Studies</ns2:grantCategory><ns2:leadFunder>Innovate UK</ns2:leadFunder><ns2:abstractText>IGEM Therapeutics Ltd aims to develop a novel HER2-targeted antibody that will address a number of unmet clinical needs. It will exploit innovative animal models, novel HER2-binding antibody domains and its innovative IgE platform technology. IgE provides a completely unique anti-cancer mode of action which enables our products to be clearly differentiated from IgG-based therapies. IGEM aims to attain a leading position in the global immune-oncology market which is forecast to reach $28 billion by 2025\.</ns2:abstractText></ns2:project>