<?xml version="1.0" encoding="UTF-8"?><ns2:project xmlns:ns1="http://gtr.rcuk.ac.uk/gtr/api" xmlns:ns2="http://gtr.rcuk.ac.uk/gtr/api/project" xmlns:ns3="http://gtr.rcuk.ac.uk/gtr/api/fund" xmlns:ns4="http://gtr.rcuk.ac.uk/gtr/api/person" xmlns:ns5="http://gtr.rcuk.ac.uk/gtr/api/project/outcome" xmlns:ns6="http://gtr.rcuk.ac.uk/gtr/api/organisation" ns1:created="2026-08-26T13:36:10Z" ns1:href="http://gtr.ukri.org/gtr/api/projects/D90E9C12-F90E-4059-85A0-36E0648A3873" ns1:id="D90E9C12-F90E-4059-85A0-36E0648A3873"><ns1:links><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/persons/C5D2E246-F486-465C-9DD0-64D25641931A" ns1:rel="PM_PER"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/76D6A85D-AA5D-4601-8C6D-7C6C5A2DC8BF" ns1:rel="LEAD_ORG"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/76D6A85D-AA5D-4601-8C6D-7C6C5A2DC8BF" ns1:rel="PARTICIPANT_ORG"/><ns1:link ns1:end="2021-03-30T23:00:00Z" ns1:href="http://gtr.ukri.org/gtr/api/funds/24E3919F-0ADF-42A6-BF97-9FFBDE4A3CFC" ns1:rel="FUND" ns1:start="2020-05-31T23:00:00Z"/></ns1:links><ns2:identifiers><ns2:identifier ns2:type="RCUK">62125</ns2:identifier></ns2:identifiers><ns2:title>Determination of the link between hypertension and Covid-19</ns2:title><ns2:status>Closed</ns2:status><ns2:grantCategory>Feasibility Studies</ns2:grantCategory><ns2:leadFunder>Innovate UK</ns2:leadFunder><ns2:abstractText>Hypertension (uncontrolled high blood pressure) is the leading preventable cause of premature death worldwide. Globally, 1.39bn people are estimated to have hypertension, and it caused ~10.7 million deaths in 2015\. It is projected to affect more than 1.5 billion people around the world by 2025\.

In the UK ~30% of adults have hypertension, 9.5m have a diagnosis, and a further 5m people in England alone may have hypertension yet be unaware.

In the current pandemic of COVID-19, people with hypertension are facing additional challenges in managing their condition as they are:

\*socially isolating and not being able to meet with their GP/Healthcare Professional (HCP) with the same frequency

\*reading stories in the press and scientific literature that indicate that a high percentage of patients with hypertension who contract COVID-19 have severe illness, are admitted to an intensive care unit, receive mechanical ventilation, or die.

Being able to remotely monitor people with hypertension through use of a phone app that records daily BP readings, current treatment regimens and indicate any COVID-19 symptoms will address a current clinical need and enable medical management and patient engagement without the need for direct patient-HCP contact.

We aim to update an already developed phone app designed for a hypertension focussed clinical study to include additional features for deployment in a new clinical trial in a COVID-19 setting. The trial will aim to demonstrate a &amp;quot;business as usual&amp;quot; approach to managing and monitoring a long term condition as well as collecting data help to answer questions that are of concern for the hypertension community namely:

\*Does blood pressure drug use and/or level of blood pressure control affect risk of COVID-19 infection?

\*Does blood pressure drug use and/or level of blood pressure control affect severity of COVID-19 illness/pneumonia?

\*Do particular types of blood pressure medication affect risk of COVID-19 infection?</ns2:abstractText></ns2:project>