900031ICURE Aid for Start Ups Cohort 3ClosedStudyInnovate UKThe Central Pattern Generator (CPG) implants, which we are developing, are a potentially disruptive medical science and technology solution enabling the effective bioelectronic treatment of a wide range of chronic diseases. Their first application will be within Cardiac Rhythm Management (CRM) market where their use will improve the life of patients, and help relieve the growing burden on medical carers and National Health resources arising from the increasing incidence of coronary disease. Although the CPG technology has a wide range of applications it will be developed initially to restore cardiac function in heart failure with indirect benefits for hypertensive and sleep apnoea patients. The advantages of neural bioelectronics include an ability to integrate, in real time, biological inputs and synchronize to physiological feedback bringing increased efficacy, safety and autonomy for the patient. CPG based therapies cause none of the side-effects arising from the long term drug use present in today's drug based therapies.