700268Anti-microbial, elastomeric and microporous coatings for metal implantsClosedGRD Proof of MarketInnovate UKMetal implants are used for bone fracture / joint replacement surgery. Osteolysis (active resorption of living bone) arises when: • Particles are released from the implant & initiate an immune response • Osteoclasts in the bone matrix are subjected to a reduced mechanical load due to stress shielding (arising from non-uniform loading) Osteolysis causes holes in bones which results in bone weakness, implant loosening and increased incidence of infection. ESP Technology Ltd plans to develop an orthopaedic implant coating which can be applied to the bone contact regions of metal implants to promote rapid osteointegration (implant fixation), reduce osteolysis & infections.