<?xml version="1.0" encoding="UTF-8"?><ns2:project xmlns:ns1="http://gtr.rcuk.ac.uk/gtr/api" xmlns:ns2="http://gtr.rcuk.ac.uk/gtr/api/project" xmlns:ns3="http://gtr.rcuk.ac.uk/gtr/api/fund" xmlns:ns4="http://gtr.rcuk.ac.uk/gtr/api/person" xmlns:ns5="http://gtr.rcuk.ac.uk/gtr/api/project/outcome" xmlns:ns6="http://gtr.rcuk.ac.uk/gtr/api/organisation" ns1:created="2026-06-03T15:52:43Z" ns1:href="http://gtr.ukri.org/gtr/api/projects/F76FB819-9FAF-49DF-91D5-7A23BE18D974" ns1:id="F76FB819-9FAF-49DF-91D5-7A23BE18D974"><ns1:links><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/6F954F87-5BC6-4D26-AAB5-2A13BEA8B6D3" ns1:rel="LEAD_ORG"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/B5C86DB8-4736-48A8-87D1-F9EB2A9CDE39" ns1:rel="PARTICIPANT_ORG"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/00E073D4-6C65-440B-B31A-80F6432EAB0D" ns1:rel="PARTICIPANT_ORG"/><ns1:link ns1:href="http://gtr.ukri.org/gtr/api/organisations/6F954F87-5BC6-4D26-AAB5-2A13BEA8B6D3" ns1:rel="PARTICIPANT_ORG"/><ns1:link ns1:end="2016-07-30T23:00:00Z" ns1:href="http://gtr.ukri.org/gtr/api/funds/06CD6538-FFB4-48CC-9D77-80FD95046781" ns1:rel="FUND" ns1:start="2014-02-01T00:00:00Z"/></ns1:links><ns2:identifiers><ns2:identifier ns2:type="RCUK">101486</ns2:identifier></ns2:identifiers><ns2:title>Advanced Titanium Implants: Controlled Nanotopographies for Dual-regulation of Bacterial and Mammalian Cell Adhesion</ns2:title><ns2:status>Closed</ns2:status><ns2:grantCategory>Collaborative R&amp;D</ns2:grantCategory><ns2:leadFunder>Innovate UK</ns2:leadFunder><ns2:abstractText>The aim of this project is to develop a high impact reduction in the risk of failure for orthopaedic implants by controlling the nano-topography of Ti implant surfaces. The project will build on two recent separate areas of research in nanofeatures and nanopatterns. The project will exploit recent technologial innovations in nano-fabrication to develop a novel nanotopography. The project is led by the global market leader in orthopaedic implants, with technical leaders in nanofabrication and nanocharacterisation. This project will develop: nano-patterned surface structures; the manufacturing method to industrially and economically generate the requisite complex surface structure; and assess the potential performance of a prototype implant surface.</ns2:abstractText></ns2:project>