Post-genomic analysis of cysteine protease function in Leishmania parasites

Lead Research Organisation: University of Glasgow
Department Name: College of Medical, Veterinary &Life Sci

Abstract

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Publications

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Ambit A (2008) An essential role for the Leishmania major metacaspase in cell cycle progression. in Cell death and differentiation

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Besteiro S (2006) The SNARE protein family of Leishmania major. in BMC genomics

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Besteiro S (2004) A potential role for ICP, a Leishmanial inhibitor of cysteine peptidases, in the interaction between host and parasite. in Molecular microbiology

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Besteiro S (2008) The AP3 adaptor is involved in the transport of membrane proteins to acidocalcisomes of Leishmania. in Journal of cell science

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Besteiro S (2006) Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major. in The Journal of biological chemistry

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Besteiro S (2007) Protein turnover and differentiation in Leishmania. in International journal for parasitology

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Carlton JM (2007) Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. in Science (New York, N.Y.)

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Denise H (2006) Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5. in BMC molecular biology

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Eschenlauer SC (2006) PFPI-like genes are expressed in Leishmania major but are pseudogenes in other Leishmania species. in FEMS microbiology letters

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Eschenlauer SC (2009) Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major. in Cellular microbiology

 
Description MRC Programme Grant
Amount £1,800,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom of Great Britain & Northern Ireland (UK)
Start 04/2008 
End 03/2013