Phosphorylation of Cardiac Troponin I by Protein Kinase D: A Novel Regulatory Pathway in Myofilament Contraction?

Lead Research Organisation: King's College London
Department Name: Unlisted

Abstract

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Description BHF Project Grant
Amount £220,000 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom of Great Britain & Northern Ireland (UK)
Start 08/2008 
End 07/2011
 
Description BHF Project Grant
Amount £159,000 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom of Great Britain & Northern Ireland (UK)
Start 08/2007 
End 07/2011
 
Description MRC Research Grant
Amount £607,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom of Great Britain & Northern Ireland (UK)
Start 02/2009 
End 10/2012
 
Title PKD adenoviral vectors 
Description Adenoviral vectors encoding wild type or mutated PKD1, or shRNA for silencing PKD1 expression. 
Type Of Material Technology assay or reagent 
Year Produced 2008 
Provided To Others? Yes  
Impact Allowed studies with cardiac overexpression or silencing of PKD1 and led to collaborative publication. 
 
Description Gene silencing vectors 
Organisation Heidelberg University
Department Mannheim Faculty of Medicine
Country Germany, Federal Republic of 
Sector Academic/University 
PI Contribution Development of adenoviral vector for silencing PKD1 expression in cardiac myocytes
Collaborator Contribution Intellectual and practical input
Impact 17322173
Start Year 2006