Clinical and biological consequences of different FLT3 mutations and/or increased FLT3 expression in patients with AML

Lead Research Organisation: University College London
Department Name: Haematology


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.


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Description Leukaemia Research Senior Bennett Fellowship
Amount £580,000 (GBP)
Organisation Leukaemia and Lymphoma Research 
Sector Charity/Non Profit
Country United Kingdom of Great Britain & Northern Ireland (UK)
Start 10/2008 
End 09/2011
Description Prognostic Significance of FLT3 mutations in AML 
Organisation Cardiff University
Country United Kingdom of Great Britain & Northern Ireland (UK) 
Sector Academic/University 
PI Contribution Data Bank of AML genomic DNA Samples and outcome data of MRC AML trials
Collaborator Contribution My project involved screening a large cohort of samples from an cohort of patients treated on the UK MRC clinical trials, and correlating these data with clinical outcome. These trials are run by the Haematology Dept at Cardiff University.
Impact Publications: 17456725, 17957027, 18606888