Suppression of LPS-induced transcription and cytokine secretion by the dietary isothiocyanate sulforaphane. (2014)

First Author: Folkard DL

Abstract

Diets rich in cruciferous vegetables are associated with lower levels of pro-inflammatory cytokines, which may contribute to potential health-promoting properties of these vegetables. We investigate whether sulforaphane (SF), an isothiocyanate (ITC) obtained from broccoli, could suppress LPS-induced transcription and subsequent pro-inflammatory cytokine secretion at a physiologically relevant concentration using in vitro models of chronic inflammation.

Bibliographic Information

Digital Object Identifier: http://dx.doi.org/10.1002/mnfr.201400550

PubMed Identifier: 25284333

Publication URI: http://europepmc.org/abstract/MED/25284333

Type: Journal Article/Review

Volume: 58

Parent Publication: Molecular nutrition & food research

Issue: 12

ISSN: 1613-4125