Suppression of LPS-induced transcription and cytokine secretion by the dietary isothiocyanate sulforaphane. (2014)

First Author: Folkard DL


Diets rich in cruciferous vegetables are associated with lower levels of pro-inflammatory cytokines, which may contribute to potential health-promoting properties of these vegetables. We investigate whether sulforaphane (SF), an isothiocyanate (ITC) obtained from broccoli, could suppress LPS-induced transcription and subsequent pro-inflammatory cytokine secretion at a physiologically relevant concentration using in vitro models of chronic inflammation.

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PubMed Identifier: 25284333

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Type: Journal Article/Review

Volume: 58

Parent Publication: Molecular nutrition & food research

Issue: 12

ISSN: 1613-4125