Combined fiber modifications both to target a(v)ß(6) and detarget the coxsackievirus-adenovirus receptor improve virus toxicity profiles in vivo but fail to improve antitumoral efficacy relative to adenovirus serotype 5. (2012)
Attributed to:
Interrogation of the adenovirus hexon: A new paradigm for virus biology and application to therapeutic gene delivery
funded by
BBSRC
Abstract
No abstract provided
Bibliographic Information
Digital Object Identifier: http://dx.doi.org/10.1089/hum.2011.218
PubMed Identifier: 22708837
Publication URI: http://europepmc.org/abstract/MED/22708837
Type: Journal Article/Review
Volume: 23
Parent Publication: Human gene therapy
Issue: 9
ISSN: 1043-0342