A complete transcriptional map of the human body: systems biology in toto
Lead Research Organisation:
University of Edinburgh
Department Name: The Roslin Institute
Abstract
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Publications
Andersson R
(2014)
An atlas of active enhancers across human cell types and tissues.
in Nature
Davis MR
(2014)
Transcriptional profiling of the human fibrillin/LTBP gene family, key regulators of mesenchymal cell functions.
in Molecular genetics and metabolism
De Rie D
(2017)
An integrated expression atlas of miRNAs and their promoters in human and mouse.
in Nature biotechnology
FANTOM Consortium And The RIKEN PMI And CLST (DGT)
(2014)
A promoter-level mammalian expression atlas.
in Nature
Schmidl C
(2014)
Transcription and enhancer profiling in human monocyte subsets.
in Blood
Schroder K
(2012)
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
in Proceedings of the National Academy of Sciences of the United States of America
Shukla R
(2013)
Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma.
in Cell
Summers KM
(2017)
Identification of the macrophage-specific promoter signature in FANTOM5 mouse embryo developmental time course data.
in Journal of leukocyte biology
| Description | This award was a travel award to support interactions with the FANTOM Consortium, in Japan. The outcomes provided an unprecedented detail of the way in which human and animal genomes are regulated during development. |
| Exploitation Route | The methods developed in this consortium are being applied in our ongoing annotation of multiple livestock species |
| Sectors | Agriculture, Food and Drink,Healthcare |