NMR relaxometry for biomedicine and advanced materials: FC-RELAX

This project aims to better exploit the role of Field-cycling (FC) relaxometry in biology, medicine and innovative materials by extending the breadth of molecular dynamics models that are available as a tool for the users. The modelling themes included here focus on specific challenges to which Fast FC relaxometry can provide major contributions, namely MRI contrast agents, medical diagnosis and batteries/supercapacitors. This cross-disciplinary approach stimulates strong interconnections between the theme leaders to explore domains ranging from nanosystems for medical applications to the imaging of cancer, and from the development of spin relaxation theories to the description of dynamics of biomolecules. For instance, the investigation of the relaxometry profiles of complex systems, as for instance nanogels, nanoparticles and nanomaterials with multiple water pools, will allow for the characterization of their mobility and for the evaluation of the exchange rate of water molecules from one pool to another, thus paving the way for improving their efficiency as diagnostic, pharmaceutical and medical devices.