Confidence in Concept 2012 - University of Nottingham
Lead Research Organisation:
University of Nottingham
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.
People |
ORCID iD |
Publications
Bass JJ
(2020)
Overexpression of the vitamin D receptor (VDR) induces skeletal muscle hypertrophy.
in Molecular metabolism
Batson J
(2017)
Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
in ACS chemical biology
Blazejewska AI
(2013)
Visualization of nigrosome 1 and its loss in PD: pathoanatomical correlation and in vivo 7 T MRI.
in Neurology
Brook MS
(2016)
Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans.
in The Journal of physiology
Brook MS
(2015)
Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling.
in FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Cox E
(2018)
MRI assessment of altered dynamic changes in liver haemodynamics following a meal challenge in compensated cirrhosis
in European Radiology Experimental
Farrash W
(2020)
Impacts of rat hindlimb Fndc5/irisin overexpression on muscle and adipose tissue metabolism.
in American journal of physiology. Endocrinology and metabolism
Filippi M
(2014)
Ultra-high-field MR imaging in multiple sclerosis.
in Journal of neurology, neurosurgery, and psychiatry
Filippi M
(2016)
MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines
in The Lancet Neurology
| Description | BBSRC Research Grant |
| Amount | £479,645 (GBP) |
| Funding ID | BB/K019104/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Dr Caroline Hoad: The causes of constipation. Reclassifying constipation using MRI and high resolution manometry to define mechanism of disease and target treatment |
| Amount | £1,600,000 (GBP) |
| Funding ID | MR/N026810/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 06/2019 |
| Description | Dr Henryk Faas: Monitoring enzyme activity with a hyperpolarized MRI biosensor |
| Amount | £148,147 (GBP) |
| Funding ID | BB/N021460/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 09/2017 |
| Description | Dunhill Medical Trust |
| Amount | £197,576 (GBP) |
| Organisation | The Dunhill Medical Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Exercise for health in type 2 diabetes: Do novel "exerkines" regulate the health benefits of physical exercise in non-communicable disease |
| Amount | £14,740 (GBP) |
| Organisation | Diabetes UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2017 |
| End | 11/2018 |
| Description | German Fund for Research |
| Amount | € 140,000 (EUR) |
| Funding ID | DFG GZ GU 1394/2-1 |
| Organisation | German Research Foundation |
| Sector | Charity/Non Profit |
| Country | Germany |
| Start | |
| Description | Impacts Of Mechanistic Target Of Rapamycin (mTOR) Inhibition On Aged Human Muscle |
| Amount | £74,237 (GBP) |
| Organisation | United Kingdom Research and Innovation |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2020 |
| End | 05/2021 |
| Description | In vivo serial neuromelanin MRI to track depigmentation in the substantial nigra of early Parkinson's |
| Amount | £429,134 (GBP) |
| Organisation | Selfridges Group Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2020 |
| End | 05/2023 |
| Description | International Rome Foundation for Functional Gastrointestinal Diseases |
| Amount | $75,000 (USD) |
| Organisation | Rome Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | |
| Description | MRC Biomedical Catalyst Developmental Pathway Funding Scheme |
| Amount | £615,065 (GBP) |
| Funding ID | MR/N006577/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2018 |
| Description | NCESM |
| Amount | £110,000 (GBP) |
| Organisation | Institute of Sport Exercise and Health (ISEH) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | NIHR i4i |
| Amount | £569,861 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | NUH Charity |
| Amount | £10,000 (GBP) |
| Organisation | Nottingham University Hospitals NHS Trust |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | Novel dynamic proteomics approaches to investigate the systems level pathology of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) |
| Amount | £124,272 (GBP) |
| Organisation | Department of Defense |
| Sector | Public |
| Country | United States |
| Start | 01/2021 |
| End | 12/2022 |
| Description | Prof Dorothy Auer: Nigrosomal imaging in Parkinson's Disease |
| Amount | $740,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 06/2016 |
| End | 05/2018 |
| Description | Swiss national research funds |
| Amount | € 460,000 (EUR) |
| Funding ID | SNF 320000-120597/1; DFG GZ GU 1394/2-1 |
| Organisation | Swiss National Science Foundation |
| Sector | Public |
| Country | Switzerland |
| Start | |
| Description | Colorectal Cancer Screen |
| Organisation | Oncimmune |
| Department | Oncimmune |
| Country | United States |
| Sector | Private |
| PI Contribution | The University and Oncimmune have collaborated to identify new autoantibody biomarkers for colorectal cancer. |
| Collaborator Contribution | Screening of relevant biomarkers |
| Impact | No significant outputs |
| Start Year | 2013 |