UK Dementias Platform
Lead Research Organisation:
University of Oxford
Department Name: Psychiatry
Abstract
The UK Dementias Platform (UKDP) is a radically new approach to dementias research, bringing together data from around 2,000,000 study participants from 22 cohorts to try and discover the causes of dementia and to find out ways of slowing it down. The platform has been funded to the level of £4.5M and invited to apply for a further £7.5M.
To achieve our goals of discovering the causes of dementia and finding out ways to slow it down, we will analyse data collected over many decades from throughout the UK to identify targets for drugs studies.
We will also enrich strategically selected cohorts to provide resources for dementias research in general. This will involve finding out how the early dementia processes begin, how our genes affect our risk of dementia and where our body goes wrong in maintaining and repairing itself.
There are many practical challenges involved in doing this work including knowing how to assess dementia in large studies where having everyone examined by a doctor would be prohibitively expensive. Another challenge is how to measure cognitive decline in the population as when people begin to decline they are frequently less motivated to do cognitive tests.
There are also important ethical issues surrounding this work and we have specific projects looking at ethical legal and social issues surrounding taking part in detailed measurement studies as well as in considering brain donation.
To help make an impact as soon as possible, we will work closely with industry partners who are best placed to turn basic scientific knowledge into effective therapies.
Even if we cannot cure dementia in the short term, it would count as a success if we found ways of slowing it down so that nobody need lose their dignity as they grew older.
To achieve our goals of discovering the causes of dementia and finding out ways to slow it down, we will analyse data collected over many decades from throughout the UK to identify targets for drugs studies.
We will also enrich strategically selected cohorts to provide resources for dementias research in general. This will involve finding out how the early dementia processes begin, how our genes affect our risk of dementia and where our body goes wrong in maintaining and repairing itself.
There are many practical challenges involved in doing this work including knowing how to assess dementia in large studies where having everyone examined by a doctor would be prohibitively expensive. Another challenge is how to measure cognitive decline in the population as when people begin to decline they are frequently less motivated to do cognitive tests.
There are also important ethical issues surrounding this work and we have specific projects looking at ethical legal and social issues surrounding taking part in detailed measurement studies as well as in considering brain donation.
To help make an impact as soon as possible, we will work closely with industry partners who are best placed to turn basic scientific knowledge into effective therapies.
Even if we cannot cure dementia in the short term, it would count as a success if we found ways of slowing it down so that nobody need lose their dignity as they grew older.
Technical Summary
The UK Dementias Platform (UKDP) is a radically new approach to dementias research, providing a highly efficient and cost-effective translation pipeline from basic discovery through to early phase trials (Fig 1). By combining the analytic and statistical power of >20 clinical and population cohorts representing 2M participants and creating a large readiness cohort, UKDP will create an optimal environment for basic discovery activities relevant to the clinical progression and human impact of dementia. Although UKDP is intended as a strategic and sustainable resource generating increasing scientific benefit over time, it will also deliver short and medium term benefits through the analysis of existing data, the enrichment of strategically selected cohorts, developing new ways of working with industry, and generating interest and further funding for dementias research generally.
A single portal informatics hub (funded in stage 1) will be used for integrating data from participating cohorts and triangulating evidence between cohorts. The stage 2 proposal focuses on providing strategic resources for EM by enriching strategically selected cohorts, addressing key methodological issues and pump-priming a programme of EM studies.
Further development of the platform is anticipated as the opportunities it provides are more widely understood. For example, predicated on the ability of the platform's ability to provide accurately risk stratification, MRC and NIHR have recently funded a deep and frequent Phenotyping (DFP) feasibility study with a view to providing a further £5M for the full study. The DFP project may be considered a stage 3 development of UKDP and is an example of how UKDP can be used to leverage further resource for dementias research.
A single portal informatics hub (funded in stage 1) will be used for integrating data from participating cohorts and triangulating evidence between cohorts. The stage 2 proposal focuses on providing strategic resources for EM by enriching strategically selected cohorts, addressing key methodological issues and pump-priming a programme of EM studies.
Further development of the platform is anticipated as the opportunities it provides are more widely understood. For example, predicated on the ability of the platform's ability to provide accurately risk stratification, MRC and NIHR have recently funded a deep and frequent Phenotyping (DFP) feasibility study with a view to providing a further £5M for the full study. The DFP project may be considered a stage 3 development of UKDP and is an example of how UKDP can be used to leverage further resource for dementias research.
Planned Impact
The platform will use several vehicles to deliver impact.
These were described in stage 1.
In summary:
For the academic community, in addition to the proposals mad in stage 1, we will develop a network of partnerships and operate a system of working groups to actively consult the UK academic community and world experts on the direction, technologies and collaborations of the platform. Our aim is to 1) base the science of the platform on the best information available, 2) create momentum in dementias research by being inclusive of, and synergistic with, other initiatives.
For industry, partnership discussions are already underway with exchanges of ides, interests and needs between academic and industry stakeholders. Industry have identified their need for access to conversion (early MVI to dementia cohorts and for experimental medicine studies to conform to regulatory requirements.
We remain committed to raising the profile of contemporary debate about dementia and its treatment. We wish to encourage a culture of commitment to solving this problem. By increasing awareness at all levels of society we intend to leverage resources for the platform and for dementia research in general, to increase awareness of the need for earlier interventions and better targeted treatment in general by health service providers and the public alike.
Engagement with the general public and with patients and carers is a very important part of our mission. This serves not only to communicate our research findings and their relevance but also to address such issues as stigma in society and the research culture in the NHS in relation to dementia and older people. In addition to using the platform web-site to communicate to the general public, we will also liaise with charities and advocate groups such as Age UK and the Alzheimer's Society to promote our work and findings and to engage them in shaping the work programme.
In addition we will have a dedicated free-phone number available 6 days a week and a communications officer at 50% FTE over 5 years whose responsibility is to develop and implement a communications and public engagement strategy.
These were described in stage 1.
In summary:
For the academic community, in addition to the proposals mad in stage 1, we will develop a network of partnerships and operate a system of working groups to actively consult the UK academic community and world experts on the direction, technologies and collaborations of the platform. Our aim is to 1) base the science of the platform on the best information available, 2) create momentum in dementias research by being inclusive of, and synergistic with, other initiatives.
For industry, partnership discussions are already underway with exchanges of ides, interests and needs between academic and industry stakeholders. Industry have identified their need for access to conversion (early MVI to dementia cohorts and for experimental medicine studies to conform to regulatory requirements.
We remain committed to raising the profile of contemporary debate about dementia and its treatment. We wish to encourage a culture of commitment to solving this problem. By increasing awareness at all levels of society we intend to leverage resources for the platform and for dementia research in general, to increase awareness of the need for earlier interventions and better targeted treatment in general by health service providers and the public alike.
Engagement with the general public and with patients and carers is a very important part of our mission. This serves not only to communicate our research findings and their relevance but also to address such issues as stigma in society and the research culture in the NHS in relation to dementia and older people. In addition to using the platform web-site to communicate to the general public, we will also liaise with charities and advocate groups such as Age UK and the Alzheimer's Society to promote our work and findings and to engage them in shaping the work programme.
In addition we will have a dedicated free-phone number available 6 days a week and a communications officer at 50% FTE over 5 years whose responsibility is to develop and implement a communications and public engagement strategy.
Organisations
- University of Oxford (Lead Research Organisation)
- University of Milan (Collaboration)
- ETH Zurich (Collaboration)
- Progressive Supranuclear Palsy Association (PSPA) (Collaboration)
- Catalan Health Institute (ICS) (Collaboration)
- University of California, San Francisco (Collaboration)
- University of Liege (Collaboration)
- Janssen Biotech, Inc. (Collaboration)
- National Institute on Aging (Collaboration)
- OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST (Collaboration)
- EMBL European Bioinformatics Institute (EMBL - EBI) (Collaboration)
- University of San Francisco (Collaboration)
- The Hong Kong University of Science and Technology (Collaboration)
- Stanford University (Collaboration)
- Ludwig Maximilian University of Munich (LMU Munich) (Collaboration)
- European Medical Information Framework (EMIF) (Collaboration)
- Life Molecular Imaging (Collaboration)
- Medical Research Council (MRC) (Collaboration)
- HARVARD UNIVERSITY (Collaboration)
- University of Luxembourg (Collaboration)
- Wellcome Trust (Collaboration)
- Newcastle University (Collaboration)
- Alzheimer's Research UK (Collaboration)
- German Centre for Neurodegenerative Diseases (Collaboration)
- University of East Anglia (Collaboration)
- UNIVERSITY OF CAMBRIDGE (Collaboration)
- UNIVERSITY OF EXETER (Collaboration)
- McGill University (Collaboration)
- UNIVERSITY OF OXFORD (Collaboration)
- Alan Turing Institute (Collaboration)
- Observational Health Data Sciences and Informatics (Collaboration)
- Janssen Research & Development (Collaboration)
- SomaLogic (Collaboration)
- UNIVERSITY OF GLASGOW (Collaboration)
- Eli Lilly & Company Ltd (Collaboration)
- Johnson & Johnson (Collaboration)
- University of California, Irvine (Collaboration)
- Apellis Pharmaceutical (Collaboration)
- UNIVERSITY OF EDINBURGH (Collaboration)
- SWANSEA UNIVERSITY (Collaboration)
- National Institutes of Health (NIH) (Collaboration)
- KING'S COLLEGE LONDON (Collaboration)
- MRC Dementias Platform UK (Collaboration)
- University of Oslo (Collaboration)
- The International Parkinson Disease Genomics Consortium (Collaboration)
- University of Southern Denmark (Collaboration)
- Eisai Ltd (Collaboration)
- JPND Research (Collaboration)
- University of Bologna (Collaboration)
- University of Göttingen (Collaboration)
- Cardiff University (Collaboration)
- University of Southern California (Collaboration)
- Bristol-Myers Squibb (Collaboration)
- IRCCS Policlinico San Donato (Collaboration)
- Amyloid Imaging to Prevent Alzheimer's Disease (Collaboration)
- Government of Wales (Collaboration)
- GlaxoSmithKline (GSK) (Collaboration)
- UNIVERSITY OF LIVERPOOL (Collaboration)
- University of Barcelona (Collaboration)
- University of Bristol (Collaboration)
- Araclon Biotech (Collaboration)
- University College London (Collaboration)
- University of Manchester (Collaboration)
- UNIVERSITY OF NOTTINGHAM (Collaboration)
- University of Gothenburg (Collaboration)
- UK Dementia Research Institute (Collaboration)
- Syracuse University (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- Polytechnic University of Milan (Collaboration)
- AstraZeneca (United Kingdom) (Collaboration)
- Ixico (Collaboration)
- University of Leuven (Collaboration)
- EU Joint Programme - Neurodegenerative Disease Research (JPND) (Collaboration)
Publications
Agarwal D
(2020)
A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders.
in Nature communications
Ahmad S
(2018)
Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study.
in Alzheimer's & dementia : the journal of the Alzheimer's Association
Akbari A
(2020)
Creating A Research Ready Data Asset and Empowering Dynamic and Efficient Research: The Sail Dementia E-Cohort (SDEC)
in International Journal of Population Data Science
Akingbuwa W
(2020)
Genetic Associations Between Childhood Psychopathology and Adult Depression and Associated Traits in 42 998 Individuals A Meta-analysis
in JAMA Psychiatry
Alex B
(2019)
Text mining brain imaging reports.
in Journal of biomedical semantics
Allan CL
(2016)
Sub-threshold depressive symptoms and brain structure: A magnetic resonance imaging study within the Whitehall II cohort.
in Journal of affective disorders
Allardyce J
(2018)
Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder.
in JAMA psychiatry
Allen N
(2020)
Mirtazapine's effect on the QT interval in medically hospitalized patients
in Mental Health Clinician
Allen ND
(2019)
A report of affective switching associated with ketamine: The case of ketamine-induced mania is not closed.
in Bipolar disorders
| Title | 3 video interviews with research participant, senior industry scientist and senior academic researcher |
| Description | Three video interviews to bring the importance of dementia research and the DPUK project to life for our general public audience through our social media channels (YouTube and Twitter). |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2017 |
| Impact | Increased awareness of DPUK and the need for investment new ways of working in dementia research. |
| URL | https://www.youtube.com/watch?v=FYlkBpb_D_A |
| Title | Animation - 'Introducing Dementias Platform UK' |
| Description | This animation has been used on the homepage and About pages of the DPUK website to give the general public an easily accessible overview of Dementias Platform UK aims and work. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2017 |
| Impact | Our audience research has shown that the general public find this animation useful in understanding the complex DPUK project. |
| URL | https://www.dementiasplatform.uk/about |
| Title | Cognitive resources leaflet and webpage |
| Description | A promotional leaflet designed to direct the target audience of dementia researchers to an information hub with guides and resources for using cognitive data |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2019 |
| Impact | The web pages have received 2,532 visits |
| URL | https://www.dementiasplatform.uk/cognition |
| Title | DPUK 5 year celebratory event video |
| Description | A video round-up of the celebratory event held in September 2019 shared with those invited to attend the event and on social media |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2019 |
| Impact | The video received 102 views on youtube and social media clips of the video uploaded to twitter were viewed 1,567times. |
| URL | https://youtu.be/Q9QIhA9Fo8A |
| Title | DPUK Linked in profile |
| Description | To generate greater engagement with industry DPUK is now as an active Linked In page with regular news updates |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2019 |
| Impact | Following our drive for greater engagement with researchers in industry with an interest in data and dementia we now regularly post updates. We have an engagment rate of 9.39% and have grown followers by 44% in six months. |
| URL | https://www.linkedin.com/company/18392913 |
| Title | DPUK newsletter (produced 3 times a year) |
| Description | The DPUK newsletter is sent three times a year to researchers, related organisations in the dementia research sector, industry companies working in dementia research and development and major funders in the dementia research sector. It features updates on the developments and opportunities in DPUK. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2017 |
| Impact | Increased awareness of DPUK resources amongst key audience groups: scientists; funders and industry. |
| Title | Data Portal communications pack |
| Description | This pack was produced an distributed to DPUK's 16 partner organisations (10 universities and 6 pharmaceutical companies) to support the promotion of the Data Portal campaign. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2018 |
| Impact | 150% increase in traffic driven to DPUK website; increased awareness amongst the dementia research community of DPUK's tools, resources, training and funding opportunities for researchers. |
| Title | Data Portal press release |
| Description | Press release to all major science publications and science desks of print media at the launch of the DPUK Data Portal. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2017 |
| Impact | None we are aware of. |
| Title | Data Portal resource hub |
| Description | Developing a hub of resources and guides that support Data Portal users from applying to analysing data. This resource hub includes fact sheets on using big data, applying for Data Portal data and learning about using the virtual desktop with a synthetic data set. Additionally there are two explainer videos describing how to identify the data you need and analyse it within the virtual desktop |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2019 |
| Impact | The resource page has been visited X times, videos have been viewed X times and the factsheets have been visited 3,521 times |
| URL | https://www.dementiasplatform.uk/for-researchers/data-portal-getting-started-with-cohort-data |
| Title | Datathon Leaflet |
| Description | A highly visual printed promotional postcard for distribution to target audiences at talke, conferences and events to drive recruitment to datathon events in Swansea, Exeter, UEA and Ulster universities. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2019 |
| Impact | The total number of visitors to the datathon recruitment pages was 828 |
| Title | Datathon recruitment web pages |
| Description | The datathon pages promote and provide guidance for those interested in joining a datathon workshop. All other datathon communication - leaflets, social media,enews - direct the audience to this hub. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2019 |
| Impact | Over the course of the year the datathon web hub received 6,728 page views. Social media posts reached 107,073 impressions and resulted in 3,108 engagements Each datathon was fully booked - with a total of 92 attending workshop events |
| URL | https://www.dementiasplatform.uk/for-researchers/data-portal-getting-started-with-cohort-data/datath... |
| Title | Great Minds animated graphic |
| Description | An animated graphic explaining the value of cohort participants to dementia clinical studies and trials. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2019 |
| Impact | Helped support the recruitment of 45 people to the Great Minds clinical studies register pilot, showing their interest in taking part in future dementia research. |
| URL | https://www.youtube.com/watch?v=TTLyYF021uA |
| Title | Information sheet |
| Description | This information sheet was sent out to our 16 partners (10 partner universities and 6 partner pharmaceutical companies) for inclusion, alongside a news feature, in internal newsletters. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2018 |
| Impact | Increased engagement from research scientists based at universities and in industry with DPUK's resources on the DPUK website and DPUK Data Portal website. Attendance at DPUK training webinars and expressions of interest/applications for DPUK's 'Discovery Award' funding opportunities for researchers. |
| Title | Leaflet |
| Description | Leaflet produced for distribution at the Alzheimer's Research UK conference. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2017 |
| Impact | The leaflet helped to raise awareness amongst the community of dementia researchers of DPUK's free tools and data resources for researchers. |
| Title | Leaflet - 2017 |
| Description | Leaflet produced for distribution at the Alzheimer's Association International Conference, attended by over 6000 researchers. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2017 |
| Impact | Increased awareness amongst the dementia research community worldwide about DPUK's tools and data resources for researchers. |
| Title | Leaflet - 2018 |
| Description | Leaflet included in the Alzheimer's Research UK 2018 conference delegate pack (going to 650 people). |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2018 |
| Impact | At the time of writing the conference itself has not yet taken place. |
| Title | MEG & ME |
| Description | With ISSF funding, out team held a series of public open evenings to discuss research of interest to the public, to define a sho set of questions and design the experiments to answer them, and then carry it out using MEG. The project was filmed, and presented at a final public discussion meeting at the Cambridge Science Festival |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2015 |
| Impact | The project clearly caught he public's imagination, and over 100 members of the public took part across the weeks. https://vimeo.com/116423919 presents a final summary video |
| URL | https://vimeo.com/116423919 |
| Title | Magazine article |
| Description | John Gallacher was interviewed for this feature in Optima magazine (a lifestyle magazine) about the importance of participation in health research. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2017 |
| Impact | Feature in Optima magazine. |
| URL | http://www.optimamagazine.co.uk/read/style/health/1628-banking-time |
| Title | Miscellaneous branded images for DPUK and Dataportal |
| Description | Various images, such as the Dataportal background image, genetic computer background and DPUK twitter badge for email signatures. |
| Type Of Art | Image |
| Year Produced | 2019 |
| Impact | - Researchers utilising the Data portal virtual desktop will now have no doubt what they are using - Any press conducted at events such as Datathons, will now capture the DPUK logo on the background of the virtual desktop, instead of the standard windows background. - Traffic is now drawn to the DPUK twitter page each time DPUK staff sends an email. |
| Title | Misplaced in Space (September 2017) |
| Description | A collaboration with University of East Anglia, to portray the impact of Dementia |
| Type Of Art | Artistic/Creative Exhibition |
| Year Produced | 2017 |
| Impact | A film of the exhibition is available; |
| URL | https://vimeo.com/229381641 |
| Title | New blog space on DPUK website |
| Description | Creating a space for new and relevant content for the target audience where DPUK researchers and partners can outline their research, achievements or experience. |
| Type Of Art | Creative Writing |
| Year Produced | 2019 |
| Impact | New blogs are key content on twitter and LinkedIn for engagement. The are regularly shared on social media. The blog section of the website has been viewed 3,461 times in a year with an average read time of over a minute |
| URL | https://www.dementiasplatform.uk/blog |
| Title | Social media videos |
| Description | Event-based video interviews for release on social media. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2019 |
| Impact | Ove the past 12 months we have created 45 social media interview videos with a range of DPUK researchers, external ECRs, Senior researchers and Professors and Charity managers. these have been viewed 23,085 times in the past year. Many of these can be seen on our Youtube channel |
| URL | https://www.youtube.com/channel/UC9OKgZG5Dq0RheCDV3upakw/videos |
| Title | Sound and Vision |
| Description | The study is in two parts. The first part consists of interviews between local artists (Visiting Researchers) and service users with a study team member (graduate student) in attendance. Each local artist will be paired with two service users, one recruited from the CPFT clozapine clinic and one recruited from the CUH memory clinic with interviews will take place at the CPFT Tennison Road clinical and at the Herchel Smith Building, respectively. There will be two interviews with each service user, each lasting around an hour. The second part is the attendance of the study team at Science Festivals to display materials and engage the general public to complete on-line questionnaires. Completed artworks will be the centrepiece for an exhibition at UK science festivals and a digital (on-line) presentation. |
| Type Of Art | Artistic/Creative Exhibition |
| Year Produced | 2022 |
| Impact | Website for project detailing output now live following COVID related delays. |
| URL | https://soundandvision.org.uk/ |
| Title | Study recruitement web page |
| Description | A public news and information page designed to allow the public to sign-up to be considered as a participant of a small imaging study. This page was part of a local and media campaign calling for volunteers |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2020 |
| Impact | 27 people registered their interest in participating. |
| URL | https://www.dementiasplatform.uk/NTAD |
| Title | Video of DPUK conference |
| Description | Video of highlights from the DPUK annual conference 2017. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2017 |
| Impact | Use in the promotion of the 2018 annual conference amongst our key audiences. |
| URL | https://www.youtube.com/watch?v=TAsOtdaHkO0 |
| Title | Women and girls in sience campaign |
| Description | The campaign for Women and Girls in Science day 2020 (11 Feb) included a video of DPUK women researchers describing how working in science is exciting and challenging, a blog from a senior researcher on working in science and having a career break posted on the University of Oxford science blog pages and illustrations of DPUK researchers by illustrator Nina Chhita on Twitter and Instagram. |
| Type Of Art | Artefact (including digital) |
| Year Produced | 2020 |
| Impact | The video and shorter video clips were viewed a total of 3,045 times Oxford Uni Tweeting of the blog received 20 retweets and 105 likes The DPUK social channels gained 38,325 impressions and 511 engagements DPUK Senior researcher's blog on the University of Oxford, Dept Psychiatry and DPUK website was viewed 2308 times |
| URL | http://www.ox.ac.uk/news/science-blog/seven-children-20-year-career-break-and-return-cutting-edge-de... |
| Description | "Talented Women for a Successful Wales" report commissioned by the Welsh Government |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | http://gov.wales/docs/det/report/160308-women-in-science-en.pdf |
| Description | ABN clinical research and academic committee, London representative |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Academy Medical Sciences Council Member |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Academy Medical Sciences Fellow |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | Academy Medical Sciences Wales Ambassador |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Alzheimer Association Educational Workshop: The basics of fluid biomarkers in AD - speaker |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Associate Director, UK Dementia Research Institute (UKDRI) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | Attend technical meeting on the Implementation of the Global Action Plan on Public Health Response to Dementia |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Attendance to TRC-D Steering Committee Meeting |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | https://www.nihr.ac.uk/partners-and-industry/industry/collaborate-with-us/dementia.htm |
| Description | Attended Association of British Neurologist's annual conference and delivered citation for ABN medallist |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | COVID advisory group |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Calman Training |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Canadian Consortium on Neurodegeneration in Aging (CCNA) |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Chief Scientific Advisor to Alzheimer's Research UK |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Chief Scientific Advisor, Welsh Government |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | Clinical Expert for a NICE Scientific Advice consultation on Alzheimer's Disease |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Contributor to a review of current dementia recruitment registers and its role for the public and research landscape |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | DPUK2Associate Director |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | DPUK is leading academic-industrial partnerships for dementia research, and coordinating the 'ecosystem' for dementia research and care in the UK. As associate Director and lead for Experimental Medicine, my role is to accelerate early phase clinical trials though partnerships with industry, academic and third-sector stakeholder collaborations |
| URL | https://www.dementiasplatform.uk/ |
| Description | Dementia Programme Board - oversee the implementation of the PM's Challenge on Dementia to 2020 |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Dementia Research Institute VIP Visit |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Deputy Chair, ABN Cognitive Disorders Advisory Group |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | N/A |
| Description | Deputy Director DPUK |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Membership of a guideline committee |
| Description | Dr D Street - Trainee Committee Member Royal College of Physicians |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The RCP Trainees Committee (TC) comprises solely medical trainees, and reflects the RCP's commitment to encouraging physicians in training to develop active roles in influencing the future of medicine. The TC has been heavily involved in shaping the new physician training pathway. |
| URL | https://www.rcplondon.ac.uk/trainees-committee |
| Description | Dr D Street: Specialty Training Committee Regional Trainee Representative (Neurology) |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The function of the Neurology Specialty Training Committee (STC) is: To advise and support Health Education England North East and Cumbria in implementing Postgraduate Medical Education relevant to their Specialty To collaborate with Health Education England North East and Cumbria in the local administration and delivery of specialist training (i.e. StR Programmes, recruitment and selection) within the regulations and guidelines of their College or Faculty To deliver, through an appropriate panel the annual review of trainees progression against the relevant curriculum. (ARCPs) |
| URL | https://madeinheene.hee.nhs.uk/neurology/STC |
| Description | Dr D Street: Trainee Member of the Association of British Neurologists Cognitive Disorders Group |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The aim of the Association of British Neurologists is to promote excellent standards of care and champion high-quality education and world-class research in neurology. The ABN's principal objectives are to: Encourage nationwide availability of excellent and equitable neurological services regardless of age, gender, ethnicity and geographic site. Promote equality of opportunity for all neurologists and neurological trainees Support neurologists and neurological trainees in their clinical practice Support neurologists and neurological trainees in their research and academic activities Increase knowledge of the nervous system and its disorders Ensure the continuing professional development of its members. Promote the education of neurological trainees and support learning of neurology throughout medical training Collaborate with the Royal College of Physicians (London, Edinburgh and Glasgow). Foster communication with patient interest groups. Maintain contacts with neurologists in developed and in developing countries. Provide guidance when required for matters relating to neurology. |
| URL | https://www.theabn.org/page/about_ |
| Description | Dr M Malpetti - Invited contribution to the World Alzheimer Report 2021 |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Publication to serve as reference for students and practitioners. |
| URL | https://www.alzint.org/u/World-Alzheimer-Report-2021.pdf |
| Description | EPAD LCS sample access committe |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | Expert in government-supported monthly ADD Chip 5m cohort meetings |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | John Gallacher is a regular expert at monthly ADD Chip design meetings - a group which aims to form a cohort [supported by the UK Government, Charities and Industry (pharma, diagnostic & digital)] which looks to create the largest risk stratified population (including by genotype) in the world. It wants to involve 5 million healthy individuals, aged 40-75. Recent successes include ADD now being set up as a company limited by guarantee with one employee (Interim COO FR). CEO interviews have taken place and CEO could be in post as early as April. CRUK to host the CEO for the first year until the company has physical premises. |
| Description | German Centre for Neurodegenerative Diseases (DZNE) scientific review |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Invitation to participate in Challenge on Dementia 2020 workshop - May 2019 |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Impact | John was personally invited to participate in a working group on research and funding as part of the government's review of the Challenge on Dementia 2020 on the afternoon of Friday 24th May. Earlier in 2019, the government published a report summarising the views of stakeholders on the progress of the Challenge on Dementia so far and set out actions for the remaining 2 years of the Challenge. The government is also looking beyond 2020 and invited stakeholders to identify priorities for a post-2025 strategy. As part of this work DHSC are facilitated 5 working groups to consider a maximum of 3 recommendations for each group. The 5 working groups will cover: 1. Technology 2. Research/funding 3. Dementia awareness 4. Risk reduction 5. Health and care delivery Martin Rossor and Hilary Evans were asked to chair the research/funding working group which will took place on Friday 24th May from 2pm-5pm in Conference Room 1, DHSC, 39 Victoria Street, London. John was asked to join these discussions and to help consider which 3 recommendations are priorities for the field to help us move the research forwards towards effective treatments. |
| URL | https://www.gov.uk/government/publications/prime-ministers-challenge-on-dementia-2020 |
| Description | Invited abstract reviewing board member at Tau2022 conference - Dr M Malpetti |
| Geographic Reach | Europe |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Served as subject specific reviewer. |
| Description | Invited abstract reviewing board member at the European Molecular Imaging Meeting - Dr M Malpetti |
| Geographic Reach | Europe |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Served as subject specific reviewer. |
| Description | Invited as expert to contribute to discussion with Chris Whitty, Chief Scientific Adviser, Department of Health and Social Care re: polygenic testing to improve health |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Impact | A draft final integrated table has been created, incorporating all inputs received, for Polygenic Risk Sscore performance for different diseases (integrated updated online version here: https://docs.google.com/spreadsheets/d/1XFbVkjpNeNexH6NvWzEcrQIF88ogQ9b6NPXy-FfeOCI/edit?usp=sharing). This table also includes the PRS generated by Genomics PLC across a number of disorders including their validations from UKBiobank. Albeit that we have amassed some very useful starter data on the spreadsheet, given the rich and diverse debate generated by this process, it seems the exam question we were set by Chris is far from answered. The next steps could be to: (i) agree a 'short-list' of conditions as being the currently most plausible (ii) examine in detail existing analyses for clinical impact and health economic impact for these disease use-cases (iii) evaluate predicted trajectory of PRS with future GWAS (ie what will PRS do in 5,10,15 years with delivery from additional GWAS) (iv) current research priorities for PRS evaluation/implementation. Breast Cancer, Coronary Artery Disease and ?colorectal cancer likely remain front-runners (driven primarily by population incidence). It was discussed whether further dialogue is warranted, and if so, what would be the best way of continuing it and bringing in those with the requisite focused expertise? For example, potentially another modest-sized closed meeting: delineated data-driven sessions focused on really unpicking health utility/specific diseases use cases and ways forwards. |
| URL | https://www.gov.uk/government/people/christopher-whitty |
| Description | Invited co-authorship for a systematic review - Dr M Malpetti |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Contribution to new or Improved professional practice |
| Impact | Publication in a major journal. |
| Description | Invited contribution to hot-topic series for the Journal of Nuclear Medicine - Dr M Malpetti |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Contribution to new or Improved professional practice |
| Description | Invited leading figure to UK Dementia Ecosystem Summit (hosted by UK DRI) |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Impact | John Gallacher was invited as a leading figure in dementia to invite to participate in a small meeting with other leaders of the UK Dementia Ecosystem to be held towards the end of March in central London. The meeting was an opportunity for him and other leaders to inform each other of their goals and aspirations, identify possible areas of synergy and collaboration and discuss the most pressing issues. Goals and achievements for the meeting included: Promote awareness of vision and goals of each participating organisation. - Define potential points of synergy and collaboration in the short, medium and long term, particularly in the following areas: • Development of tools for translational research and experimental medicine • Understanding the breadth of symptoms that make up the spectrum of dementia: communication between basic and clinical science • Care research and technology - Define a clear message engaging the Government to sustain dementia research. |
| URL | https://ukdri.ac.uk/news-and-events/dementia-ecosystem-uk-action-through-alliance |
| Description | Invited to review Clinical Trials Regulation by Medicines and Healthcare products Regulatory Agency (MHRA) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | This policy review has been launched following the United Kingdom's departure from the European Union. It aims to design a world-class sovereign regulatory environment for clinical trials that will support the development of innovative medicines and ensure that the UK retains and grows its reputation as world leading base for life sciences, generating opportunities for skilled jobs in the UK. |
| Description | JGallacher contribution to IHCC Policy Working Group |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | John Gallacher contributed to the discussion surrounding streamlining policy development for the IHCC strategy. IHCC aims to create a global platform for translational research - informing the biological and genetic basis for disease and improving clinical care and population health. It includes the opinion of the PIs of the top 100 largest cohorts globally, so includes the work of DPUK. |
| URL | https://ihccglobal.org/ |
| Description | JGallacher contribution to Our Future Health Design Group monthly meeting |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | JGallacher contribution to the design of one of the UK's largest cohort studies involving members of the public, including the application of online cognitive tests. Our Future Health will be the UK's largest ever health research programme, designed to help people live healthier lives for longer through the discovery and testing of more effective approaches to prevention, earlier detection and improved treatment of diseases. |
| URL | https://www.closer.ac.uk/event/our-future-health/ |
| Description | JGallacher contribution to Register of Registers meeting - streamlining national efforts to recruit to dementia studies |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | JGallacher contribution to Register of Registers meeting - streamlining national efforts to recruit to dementia studies in order to remove barriers to members of the public and those part of cohort studies to sign up to research efforts. The meeting was attended by several register keepers and PIs to agree eg that the CSR/Great Minds effort should be listed on the Join Dementia Research webpage for improved visibility. |
| URL | https://www.greatmindsfordementia.uk/dementias-platform-uk |
| Description | JPND SAB Meeting - re-launching its Strategic Research and Innovation Agenda (SRIA) |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Keynote presentation on DPUK at Westminster Health Forum policy conference - 'Improving dementia outcomes in England: research, personalised care and health and social care integration' |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The agenda: Progress on meeting the goals of the Dementia 2020 Challenge and priorities for moving forward post-2020; Developing an integrated approach to improving dementia outcomes in Birmingham; Integrating health and social care - workforce development, creating dementia-friendly communities and the role of technology; Personalised care in practice - addressing barriers, increasing access and supporting patient choice; Key issues for regulating dementia services; Next steps for dementia research - funding, translating research into practice and improving patient participation: Supporting research to improve dementia outcomes; Data in the digital age for dementia research: Dementias Platform UK; Collaboration with industry partners: and Encouraging the translation of research into clinical practice. |
| URL | https://www.westminsterforumprojects.co.uk/publication/dementia-care-in-England-19 |
| Description | Long-term and regular involvement in the IHCC Policy Working Group |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | John is a representative on the Policy team (Team C) for the formation of the International Hundred K+ Cohorts Consortium (IHCC). The IHCC represents the 100 largest cohorts globally (mostly those who include over 100k participants) and aims to improve the work of cohorts on an international scale,. IHCC have facilitated discussions on improving prospects for compatibility of cohort elements (e.g., instruments, data formats, phenotype measures, & consents), promoting data and specimen sharing & open access policies, examining potential for collaborative genome sequencing/analysis, and exploring feasibility of a searchable global cohort registry. The overall charge of the Policy Team is to create a policy agenda to facilitate and optimise impact of assembling cohorts. A draft IHCC Guidance for Collaboration with Industry has been created, with thoughts of also producing a publication. |
| URL | https://ihcc.g2mc.org/teamc/ |
| Description | MRC Dementias Platform UK 'Open Science Champion' and Steering Group member |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| URL | http://www.mrc.ac.uk/research/facilities-and-resources-for-researchers/dementias-platform-uk/governa... |
| Description | Medicines Discovery Institute MDI |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Member of new Governmental Ministerial Commission on Concussion in Sport |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | https://www.gov.uk/government/news/government-to-develop-new-protocols-around-concussion-in-sport |
| Description | Member of the Bevan Commission Working Group |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Member, Biobank access committee, Brains for Dementia Research |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | NMHRI management |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Organising committee member AAIC Neurosciences Next - Dr M Malpetti |
| Geographic Reach | North America |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Postgraduate training |
| Description | Participation as expert in Population Research Resource landscape review - November 2019 |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Impact | John was invited as expert to comment on a landscape review and lessons learnt document from existing population research resource initiatives. Wellcome is working with the MRC and the ESRC to identify what kind of new Population Research Resource is required to capitalise on the rich longitudinal data and biological samples from the wealth of UK large-scale, long-term population based studies (including cohort studies). Their focus is on enabling cross-study research through the discoverability and sharing of longitudinal data and samples, linking these data with administrative, health and other routine records, and encouraging best practice. At the Population Research Resource Workshop held on the 24th May 2019 (which John also participated) a list of existing initiatives that support longitudinal population studies in the UK were identified, along with a list of functions that these initiatives may provide. Wellcome have now commissioned to write a short report by November 29th 2019 to provide them with a description and "lessons learnt" review of these existing initiatives. The first stage of the review was to provide a one-page summary of existing initiatives from publically available information on the websites of these initiatives that describes the resource, its purpose and objectives, and the functions provided. The second stage of the review was to contact the lead of each initiative by email to obtain further information to clarify these summaries that will form an appendix in the report. John completed an in-depth questionnaire and 1:1 interview on his view of the landscape. |
| Description | Participation in June 22 DEMON Network Summit, Royal Society of Medicine |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The summit brought together leading scientists, clinicians, funders, and industry representatives to identify how contemporary data science and artificial intelligence approaches can help to tackle dementia and promote brain health. Discussions were also held on how to develop a sustainable community to accelerate progress and change the landscape to support a more innovative and integrated approach. |
| URL | https://demonsummit2022.com/ |
| Description | Participation in an advisory committee - Alzheimer Research UK Scientific Advisory Board Chair (2021) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | ARUK is a major funder of Alzhiemer's disease related research in the UK. Serving as chair on this advisory board has had a significant impact in helping ARUK direct their funding towards areas of greatest impact, as well as helping researchers build effective collborations resulting in meaningful insights improving patient care and informing policy. |
| Description | Press conference |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Proposal sent to UK Biobank titled 'Proposal: Subjective memory questions in UK Biobank' |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Proposal to UK Biobank titled 'Proposed cognitive tests for an enhanced UK Biobank cognitive battery' |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Reinvigorating health registries during COVID for rapid policy analyses |
| Geographic Reach | Europe |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | https://www.registerkonferansen.no/ |
| Description | Report sent to UK Biobank titled 'Observation of the enhanced UK Biobank cognitive assessment' |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Report sent to UK Biobank titled 'Recommendations on the retention of cognitive tests in the UK Biobank cognitive test battery' |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Report to UK Biobank on the UK Biobank cognitive assessment titled 'Test characteristics of the enhanced UK Biobank Cognitive Assessment' |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Representative on SAIL Databank Scientific External Advisory Board (Dec 2019) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | The SAIL Scientific External Advisory (SEA) Board discussed and generated actions in relation to topics such as new data types / usages and resulting information governance challenges; Data proportionality v. the demand for programme level data, and Development of a Public Involvement & Engagement policy/strategy for SAIL. |
| URL | https://saildatabank.com/ |
| Description | Sceintific Advisory Board Meber for AI-MIND |
| Geographic Reach | Europe |
| Policy Influence Type | Influenced training of practitioners or researchers |
| URL | https://www.ai-mind.eu/partners/ |
| Description | Speaking at ARUK Policy conference: Looking forward: Towards dementia treatment - planning for the requirements to deliver new treatments for AD in the UK |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Standard Operating Procedures sent to UK Biobank - SOPs for IQCODE |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Talk at International Cohorts Summit, Iceland - April 2019 |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | IHCC convened the second International Cohorts Summit in Reykjavik, Iceland April 2019 with the intent of developing the scientific agenda to drive the research and collaboration between cohorts and present Team activities and progress on goals that were established as the result of the first International Cohorts Summit held in March 2018. The primary objectives of this meeting were to: Identify scientifically meritorious cross-cohort research projects and identify international collaborators willing to organize and participate in them Develop an IHCC scientific agenda to bring forward to funding bodies The International Cohorts Summit was conceived by the Heads of International Research Organizations (HIROs) chaired by Jeremy Farrar of the Wellcome Trust, with an inaugural summit held in March 2018 in Durham, North Carolina, USA, organized by the Global Genomic Medicine Collaborative (G2MC), with the goal of enabling leaders of large-scale longitudinal cohorts worldwide to share best practices, discuss data sharing, explore standards, discuss common challenges, and explore the potential for a large(r) collaborative sequencing strategy. From that Summit, the International HundredK+ Cohorts Consortium (IHCC) was formed, with teams assembled to address the actions identified in this Summit. John Gallacher was invited to contribute alongside the PIs of the most influential cohorts and their funders internationally to discuss remedies to challenges and opportunities faced by cohorts. This particular summit involved giving a pitch by Dr Sarah Bauermeister on behalf of Team C's work on policy. The pitch was on a precision medicine approach to multi-morbidity in cardio-metabolic disease and dementia, and the resources required for this. The DPUK Data Portal was demonstrated as a world-leading tool in data curation and analysis instrumental to the cause. Sarah was approached several times from international funding and policy leaders in the field, and engaged for further collaboration. One major impact was an invitation from China to attend a workshop discussing how DPUK and the Data Portal could aid research in Asia. |
| URL | https://ihcc.g2mc.org/ics2019/ |
| Description | The Secure Anonymised Information Linkage System |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | UCL ageing event - cultivating research connections across the university: organising committee and plenary speaker |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | UK Biobank - long-term and regular attendance as a representative on the UKB Steering Committee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | John is a long-term and regular representative at the tri-annual UKB steering committee meetings in London, as well as UKB's annual International Scientific Advisory Board. John provides expertise and leadership on cognitive and psychological assessments. His work for UK Biobank provides a regular touch-point for DPUK, with the platform benefiting from John's detailed and up-to-date knowledge UKB's resources and direction. |
| URL | https://www.ukbiobank.ac.uk/steering-committee/ |
| Description | UK representative - European Academy of Neurology Dementia Panel |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Vice Chair and Chair Elect, Advisory Council US Alzheimer's Association ISTAART |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | WHO's Global Dementia Observatory discuss the implementation of the global action plan on public health response to dementia 2017-2025 |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Description | Work group to establish a Danish brain research centre - Lundbeckfonden, The Brain Prize |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Working Group Lead on Emeritus Professor John Bell's response to potential increase in Dementia governmental funding |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | Following a recent a Conversative goverment pledge (https://www.bbc.co.uk/news/election-2019-50523507), it is anticipated that there will be significant new UK Government funding for dementia research. As additional funding will probably be focussed in areas identified as particularly challenging to drug discovery, it will probably leverage in considerable matched, pre-competitive industry funding. Further, it is likely that this investment will be in translational research - complementing existing Dementia Research Institute activity in basic research. In the -omics era major discoveries driven by genomics, proteomics and metabolomics have uncovered the key protein pathways, cellular pathology within the brain and the systemic effects of the disease involving the vascular system and the gut-liver-brain axis. In next decade, bridging the gap between target discovery and clinical interventions is one of the major challenges. The interest of industry appears to be focussed on target validation and human experimental medicine. To make a strong Oxford offer, it was proposed to need to take stock of current strengths and identify key gaps. It was thought this relevant work in Oxford takes place across multiple Departments and will require coordination, as will the relevant infrastructure. This aim of this workshop was to develop Oxford's strategy for expanding dementia research, maximising the potential for both local research and for collaborations with national programmes including the Dementia Research Institute (DRI), Dementia Platform UK (DPUK) and ARUK Drug Discovery Institutes (DDI). The three major areas of focus for the meeting included target discovery and validation; Big Data and multi-omics data integration, and Experimental Medicine. As a result of the meeting, John Gallacher was asked to be chair of one of the four working groups ('Biobanks/Clinical follow-up studies/Epidemiology'). A decision was taken to build Oxford's translational research offering in dementia to a higher level allowing Oxford to secure transformational funding in the £50m+ range from industry, government and philanthropic sources. Each group was asked to: i) map current landscape ii) map future landscape required iii) identify capability gaps. iv) Propose how we can fill capability gaps and outline a. the required capability i.e. new posts, new equipment, shared resources, new/existing technology, new approaches etc. b. the resources/funding required. c. a timeline e.g. if recruitment is required for a strategic appointment or new equipment is ordered/infrastructure built In a document structured as suggested above. John's working group was asked to identify a clinical lead seeing patients in Oxford to:- a. Ensure we are biobanking rich patient material in Oxford (CSF, skin biopsies etc..) b. Build up our UK clinical network in advance of the bid with inter-institutional alliances to complement our translational offering. A revised draft of a white paper is being produced, setting out the overall scientific vision. The more detailed granular output of the working groups will be fed into this i.e. the additional capability building required, resources necessary and implementation timeline. |
| Description | World Dementia Council |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | "A multi-centre randomised controlled trial of the clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury" |
| Amount | £1,988,751 (GBP) |
| Organisation | NIHR London (South) CRN |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2021 |
| End | 08/2024 |
| Description | "Clinician training partnership: vascular contribution to dementia": Clinical Training Partnership awarded to W Whiteley, JM Wardlaw, G Hardingham, CW Ritchie, C Smith, A Williams, K Horsburgh, H Whalley, S Munoz Maniega |
| Amount | £225,000 (GBP) |
| Funding ID | 3699 |
| Organisation | Alzheimer's Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2019 |
| End | 07/2022 |
| Description | "Dementias Platform UK" Co-applicant with principal applicant John Gallacher (Oxford) and co-applicants Ronan Lyons, James Rowe, Carol Routledge, Declan Jones |
| Amount | £7,500,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 12/2025 |
| Description | "Integrative imaging of brain structure and function in populations and individuals" (awarded to Mark Woolrich) |
| Amount | £570,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 12/2024 |
| Description | "Small Vessel Disease - Spotlight on Symptoms (SVD-SOS) - Improving recognition of symptoms and signs of progressing cerebral small vessel disease-related brain damage to prevent cognitive decline, dementia and stroke" (Doubal F, Wardlaw, JM) |
| Amount | £24,962,394 (GBP) |
| Funding ID | SA PG 19\100068 |
| Organisation | Stroke Association |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2019 |
| End | 07/2022 |
| Description | "Synaptic Health In Neurodegeneration" PI Prof James B Rowe Co-applicants Kia Nobre and Mark Woolrich |
| Amount | £400,000 (GBP) |
| Organisation | MRC Dementias Platform UK |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2021 |
| End | 09/2024 |
| Description | "UK DRI IPSC platform to model Alzheimer's disease risk (IPMAR) " |
| Amount | £1,866,149 (GBP) |
| Organisation | UK Dementia Research Institute |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 07/2023 |
| Description | "Wellcome Centre for Integrative Neuroimaging" (awarded to Kia Nobre and Mark Woolrich) |
| Amount | £2,801,188 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2022 |
| End | 03/2024 |
| Description | 1946 ARUK |
| Amount | £1,824,093 (GBP) |
| Funding ID | ARUK-PG2014-1946 |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2014 |
| End | 06/2017 |
| Description | A longitudinal amyloid-PET/MRI study of the 1946 birth cohort. ARUK-PG2017-1946. |
| Amount | £1,216,062 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2017 |
| End | 06/2019 |
| Description | A standardized, multilingual, mini linguistic state examination (MLSE) for classifying and monitoring primary progressive aphasia. |
| Amount | £358,924 (GBP) |
| Funding ID | RG82683 |
| Organisation | St George's University |
| Sector | Academic/University |
| Country | Grenada |
| Start | 01/2017 |
| End | 12/2019 |
| Description | A*-STAR Scholarship (Supervisor to Quyen Do). Advanced 3D co-culture iPSC-derived models of Parkinson's |
| Amount | $206,382 (SGD) |
| Organisation | Agency for Science, Technology and Research (A*STAR) |
| Sector | Public |
| Country | Singapore |
| Start | 01/2018 |
| End | 09/2022 |
| Description | ABBUK Brains for Dementia Research Programme (extension) |
| Amount | £404,390 (GBP) |
| Funding ID | 504291 |
| Organisation | Alzheimer’s Brain Bank UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2013 |
| End | 03/2018 |
| Description | ABBUK Brains for Dementia Research Programme (extension) |
| Amount | £2,598,988 (GBP) |
| Organisation | Alzheimer’s Brain Bank UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2021 |
| Description | ARUK East Network Travel Grant - Dr M Malpetti |
| Amount | £1,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2022 |
| Description | ARUK Illustration Award 2021 given to Bryan Ng |
| Amount | £200 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2021 |
| End | 08/2021 |
| Description | ARUK Illustration Award 2023 given to Ajantha Abey |
| Amount | £200 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 05/2023 |
| Description | ARUK Illustration Award 2023 given to Rachel Heon Roberts |
| Amount | £200 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 05/2023 |
| Description | ARUK ODDI collaboration: Phenotypic drug discovery in Parkinson's |
| Amount | £200,000 (GBP) |
| Organisation | University of Oxford |
| Department | Alzheimer's Research UK Oxford Drug Discovery Institute |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 12/2020 |
| Description | ARUK Oxford Pilot Investigating the effect of tau on axonal transport and tau release in MAPT-iPSC cortical neuron models |
| Amount | £4,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | ARUK Oxford Pilot Optogenetic light source and controller for 96/384-well plates to allow uniform illumination of wells inside a cell-culture incubator. |
| Amount | £4,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | ARUK Pilot Analysis of tau secretion in iPS differentiated neuronal cultures |
| Amount | £4,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | ARUK Pilot Award 2020-21 given to Dr Charmaine Lang & Mr Peter Kilfeather |
| Amount | £2,297 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 08/2021 |
| Description | ARUK Pilot Award 2020-21 given to Maria Claudia Caiazza |
| Amount | £2,500 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 08/2021 |
| Description | ARUK Thames Valley Illustration Award 2023 |
| Amount | £250 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 02/2023 |
| Description | ARUK Thames Valley Network Pilot Award 2022 |
| Amount | £2,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2022 |
| End | 12/2023 |
| Description | ARUK Thames Valley Network Travel Award for Becky Carlyle |
| Amount | £168 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2022 |
| End | 12/2022 |
| Description | ARUK Thames Valley Network Travel Award for Brent Ryan to attend two conferences |
| Amount | £54,095 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2022 |
| End | 12/2022 |
| Description | ARUK Thames Valley Network Travel Award for Helle Barknob |
| Amount | £138 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 11/2022 |
| End | 12/2022 |
| Description | ARUK Thames Valley Network Travel Award for Hugo Fernandes |
| Amount | £211 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2022 |
| End | 02/2023 |
| Description | ARUK Thames Valley Network Travel Award for Maria Claudia Caiazza |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2022 |
| End | 12/2022 |
| Description | ARUK Thames Valley Network Travel Award for Rachel Heon Roberts |
| Amount | £600 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2022 |
| End | 01/2023 |
| Description | ARUK Thames Valley Network Travel Award for William McGuinness |
| Amount | £500 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2022 |
| End | 01/2023 |
| Description | ARUK Thames Valley Network travel award: Mootaz Salman |
| Amount | £600 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2022 |
| End | 12/2023 |
| Description | ARUK Travel Award 2020-21 given to Kaitlyn Cramb to attend & present at AD/PD conference in Barcelona |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 03/2022 |
| Description | ARUK Travel Award 2020-21 given to Martha Lavelle |
| Amount | £100 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2021 |
| End | 09/2021 |
| Description | ARUK Travel Award 2020-21 given to Quyen Do to attend Ion channels in Synaptic and Neural Circuit Physiology online conference |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2021 |
| End | 06/2021 |
| Description | ARUK Travel Award given to Ajantha Abey to attend ARUK Early Careers Day and Research Conference 2022 |
| Amount | £126 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2022 |
| End | 03/2022 |
| Description | ARUK Travel Award given to Ajantha Abey to attend ARUK Early Careers Day and Research Conference 2023 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to Akansha Mehta to attend ARUK Research Conference 2023 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to Bryan Ng to attend ARUK Early Careers Day and Research Conference 2022 |
| Amount | £205 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 03/2022 |
| Description | ARUK Travel Award given to Charmaine Lang to attend ARUK Research Conference 2023 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to Gizem Onal to attend ARUK Research Conference 2023 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to Jonah-Wolf Schreier to attend ARUK Research Conference 2023 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to Kaitlyn Cramb to attend Federation of European Neuroscience Societies Regional Meeting 2023 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2023 |
| End | 05/2023 |
| Description | ARUK Travel Award given to Maria Claudia Caiazza to attend AD/PD conference 2022 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 03/2022 |
| Description | ARUK Travel Award given to Maria Claudia Caiazza to attend Parkinson's Disease Theme ECR workshop Meeting 2023 |
| Amount | £204 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to Mootaz Salman to attend ARUK Research Conference 2023 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to Mootaz Salman to attend Brain 2022 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2022 |
| End | 07/2022 |
| Description | ARUK Travel Award given to Nancy Ahuja to attend ARUK Research Conference 2023 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to Naroa Ibarra Aizpurua to attend UKDRI - Parkinson's Disease Theme ECR Workshop 2023 |
| Amount | £96 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2023 |
| End | 03/2023 |
| Description | ARUK Travel Award given to William McGuinness to attend AD/PD conference 2022 |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 03/2022 |
| Description | ARUK Travel grant |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2019 |
| End | 08/2019 |
| Description | ARUK network pilot grant |
| Amount | £5,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2019 |
| Description | Addenbrooke's Charitable Trust |
| Amount | £59,172 (GBP) |
| Organisation | Addenbrooke's Charitable Trust (ACT) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2023 |
| Description | Airwave Health Monitoring Study (AHMS) |
| Amount | £23,908 (GBP) |
| Funding ID | WPEA_P72447 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2020 |
| End | 06/2023 |
| Description | Ajantha Abey, The Clarendon Fund & Department of Physiology, Anatomy, and Genetics Scholarship. Project title: Understanding Selective Neuronal Vulnerability in Alzheimer's and Parkinson's Disease and Potential Remedies Through Patient-Derived Stem-Cells |
| Amount | £125,097 (GBP) |
| Organisation | University of Oxford |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2020 |
| End | 09/2023 |
| Description | Alzheimer's Disease Data Enablement Fund sponsored project: Traumatic brain injury, emotional adversity and the long-term effects on adult outcomes and dementia. |
| Amount | £612,845 (GBP) |
| Organisation | National Philanthropic Trust |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 03/2019 |
| End | 12/2019 |
| Description | Autophagic flux |
| Amount | £317,137 (GBP) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 09/2017 |
| End | 08/2019 |
| Description | Awarded an Oxford ARUK Small Equipment Award to purchase an Oxford Nanopore MinION |
| Amount | £3,670 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2019 |
| End | 07/2019 |
| Description | BHF Research Excellence Award |
| Amount | £3,000,000 (GBP) |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2019 |
| End | 04/2024 |
| Description | BRC award to UCL/H (Dementia Theme) |
| Amount | £5,000,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 04/2022 |
| Description | Becky Carlyle - Subcellular proteomic signatures of Alzheimer's disease. |
| Amount | $64,000 (USD) |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 01/2022 |
| End | 12/2024 |
| Description | Bioinformatics and Functional Genomics |
| Amount | £1,250,000 (GBP) |
| Organisation | UK Dementia Research Institute |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2023 |
| End | 03/2028 |
| Description | Biomedical Research Centre Dementia Theme |
| Amount | £118,000,000 (GBP) |
| Funding ID | RG85367 |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 03/2022 |
| Description | Brain Network Analysis in Neurodegenerative Tauopathies |
| Amount | £22,391 (GBP) |
| Funding ID | RG89925 |
| Organisation | The Evelyn Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 12/2019 |
| Description | Brain Research Trust |
| Amount | £219,355 (GBP) |
| Organisation | Brain Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2019 |
| Description | Brain Research Trust |
| Amount | £219,355 (GBP) |
| Organisation | Brain Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2019 |
| Description | Brains for Demention Research Programme |
| Amount | £225,571 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2013 |
| End | 03/2018 |
| Description | Bridging the gap: biophysical models of human frontotemporal lobar degeneration |
| Amount | £2,025,694 (GBP) |
| Funding ID | 220258/Z/20/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2021 |
| End | 03/2026 |
| Description | British Heart Foundation - Cardiovascular mechanisms linked to cerebral amyloid b deposition and cognitive decline: a sub study of INSIGHT 46 |
| Amount | £273,844 (GBP) |
| Funding ID | PG/17/90/33415 |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 04/2022 |
| Description | British Heart Foundation - NIHR - Bloomsbury Centre for clinical phenotyping (BBCP): infrastructure Grant |
| Amount | £776,285 (GBP) |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2019 |
| End | 12/2019 |
| Description | Centre for Ageing and Dementia Research (CADR) |
| Amount | £386,341 (GBP) |
| Organisation | Welsh Assembly |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2020 |
| Description | Cerebrovascular health in older adults at a genetic risk for dementia |
| Amount | £3,970 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 08/2018 |
| Description | Clinical research infrastructure |
| Amount | £6,995,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 09/2020 |
| Description | Clinical research infrastructure |
| Amount | £1,500,000 (GBP) |
| Organisation | University of Cambridge |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2016 |
| Description | Collaborative award: Integrative imaging of brain structure and function in populations and individuals. Co-applicant with lead applicant Stephen Smith, Saad Jbabdi, Mark Jenkinson, Karla Miller (University of Oxford), Christian Beckmann (Radboud) |
| Amount | £4,106,203 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 12/2025 |
| Description | Compartmentalised calcium handling in dopamine neurons: importance for selective vulnerability in Parkinson's. |
| Amount | £3,700,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2022 |
| End | 04/2027 |
| Description | DRI Costs |
| Amount | £1,123,799 (GBP) |
| Organisation | UK Dementia Research Institute |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 08/2022 |
| Description | Dayne Beccano-Kelly Lockey Fund- for travel to World Parkinson's congress |
| Amount | £500 (GBP) |
| Organisation | Lockey Committee |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 02/2019 |
| End | 04/2019 |
| Description | Decision making and dementia: from mechanisms to clinical trials |
| Amount | £1,930,000 (GBP) |
| Funding ID | MC_UU_00030/14 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2022 |
| End | 03/2027 |
| Description | Deconvoluting the dementia phenotype using functional genomics and computational approaches |
| Amount | £537,913 (GBP) |
| Organisation | Government of Wales |
| Department | Welsh European Funding Office |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 10/2022 |
| Description | Deep and Frequent Phenotyping; combinatorial biomarkers for dementia experimental medicine |
| Amount | £6,301,078 (GBP) |
| Funding ID | MR/N029941/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 09/2020 |
| Description | Dementias Platform |
| Amount | £6,618,190 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2014 |
| End | 06/2019 |
| Description | Dept MRC Studentship (Principal Supervisor to Naroa Ibarra Aizpurua, Co-supervisor Dr Sally Cowley; Understanding the contribution of astrocytes to Parkinson's. |
| Amount | £15,900 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2020 |
| End | 09/2022 |
| Description | Developing new therapeutic drugs in pre-clinical models of Parkinson's. |
| Amount | $200,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 07/2021 |
| End | 02/2023 |
| Description | Dr Andrea Loreto Sir Henry Wellcome postdoctoral fellowship. Project title: The role of the Wallerian axon-death pathway in neuronal and axonal vulnerability in Parkinson's disease |
| Amount | £250,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 04/2022 |
| Description | Dr Becky Carlyle: Exploiting sub-cellular proteomics and high-throughput validation screens to define the role of proteome complexity in Alzheimer's Disease |
| Amount | £420,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2022 |
| End | 09/2025 |
| Description | Dr Charmaine Lang & Mr Peter Kilfeather were awarded an ARUK Thames Valley Pilot Award |
| Amount | £2,297 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 06/2021 |
| Description | Dr Mootaz Salman was awarded an ARUK Thames Valley Network Small Equipment Award 2020 |
| Amount | £2,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2020 |
| End | 03/2021 |
| Description | Dr Phillipa Carling was awarded an ARUK Thames Valley Network ECR award |
| Amount | £349 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2020 |
| End | 12/2020 |
| Description | Dr Sally Cowley Co-Investigator. Establishing a platform in human iPS-macrophages for interrogation of the STING pathway in Parkinson's. |
| Amount | £123,000 (GBP) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | |
| Description | Dr Sally Cowley Co-applicant/Co-supervisor. Targeting crosstalk between microglia, astrocytes and neurons in Alzheimer's disease pathology |
| Amount | £500,000 (GBP) |
| Organisation | Eli Lilly & Company Ltd |
| Sector | Private |
| Country | United Kingdom |
| Start | |
| Description | Dr Stefania Giussani was awarded an ARUK Thames valley network ECR Award |
| Amount | £493 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2020 |
| End | 12/2020 |
| Description | Drake Foundation: Effects of head injury the NSHD 1946 birth cohort. |
| Amount | £60,852 (GBP) |
| Organisation | The Drake Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 04/2019 |
| Description | Drake Foundation: Head Injury, cognition and imaging correlates of dementia in the Insight 46 cohort |
| Amount | £60,852 (GBP) |
| Organisation | The Drake Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 04/2019 |
| Description | EC ERASMUS+, European University of Brain and Technology (NeurotechEU) (awarded to Kia Nobre) |
| Amount | € 422,000 (EUR) |
| Organisation | European Council |
| Sector | Public |
| Country | Belgium |
| Start | 10/2020 |
| End | 09/2023 |
| Description | EC Horizon, European University of Brain and Technology - Research & Innovation (awarded to Kia Nobre) |
| Amount | £230,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 04/2021 |
| End | 09/2023 |
| Description | ECR grant award for Bryan Ng |
| Amount | £425 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2020 |
| End | 03/2021 |
| Description | EM7 Connectivity changes in early Alzheimer's Disease. |
| Amount | £94,384 (GBP) |
| Funding ID | MC_ST_CBU_2019 |
| Organisation | MRC Doctoral Training Program |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 09/2023 |
| Description | EM7 NTAD: new-therapeutics-in-alzheimers-disease |
| Amount | £1,200,000 (GBP) |
| Organisation | MRC Dementias Platform UK |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 06/2018 |
| End | 09/2020 |
| Description | EM7 UCB-J PET |
| Amount | £370,000 (GBP) |
| Organisation | Janssen Research & Development |
| Sector | Private |
| Country | Global |
| Start | 09/2019 |
| End | 06/2020 |
| Description | EU IMI-2. Amyloid imaging to prevent Alzheimer's disease (AMYPAD) |
| Amount | £934,500 (GBP) |
| Organisation | European Social Survey: European Research Infrastructure Consortium (ESS ERIC) |
| Sector | Charity/Non Profit |
| Country | European Union (EU) |
| Start | 10/2016 |
| End | 09/2021 |
| Description | Early-onset depression: Characterising development and identifying risks |
| Amount | £763,680 (GBP) |
| Funding ID | MR/R004609/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2017 |
| End | 11/2020 |
| Description | Elliot Mock - Validation of USP14 as a therapeutic target in Parkinson's disease. |
| Amount | £150,000 (GBP) |
| Organisation | Netherlands Organisation for Scientific Research (NWO) |
| Sector | Public |
| Country | Netherlands |
| Start | 10/2021 |
| End | 09/2023 |
| Description | Enhancing autophagic flux in Parkinson's disease |
| Amount | $663,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 10/2017 |
| End | 09/2019 |
| Description | Expanding DPUK genetics and integrating with inflammation/immunity research |
| Amount | £100,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2019 |
| Description | FENS travel award for Bryan Ng |
| Amount | € 75 (EUR) |
| Organisation | Federation of European Neuroscience Societies (FENS) |
| Sector | Private |
| Country | Belgium |
| Start | 07/2020 |
| End | 07/2020 |
| Description | Farr NLP open source software development |
| Amount | £48,470 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2017 |
| End | 10/2018 |
| Description | Functional screening of Parkinson's GWAS loci in human iPSC neurons |
| Amount | £1,400,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 12/2020 |
| End | 06/2024 |
| Description | GENetic Frontotemporal dementia Imaging - Second phase (GENFI-2) |
| Amount | £2,613,582 (GBP) |
| Funding ID | MR/M023664/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 04/2020 |
| Description | Gates Ventures Interoperability Funding |
| Amount | £612,845 (GBP) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 02/2019 |
| End | 04/2020 |
| Description | Genetics collaboration with Prof Bart De Strooper UK DRI programme |
| Amount | £50,000 (GBP) |
| Organisation | UK Dementia Research Institute |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2021 |
| End | 04/2022 |
| Description | Genetics collaboration with Prof Bart De Strooper UK DRI programme |
| Amount | £50,000 (GBP) |
| Organisation | UK Dementia Research Institute |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2021 |
| End | 04/2022 |
| Description | HDR UK Multiomics |
| Amount | £77,625 (GBP) |
| Funding ID | CFC0107 |
| Organisation | Health Data Research UK |
| Sector | Private |
| Country | United Kingdom |
| Start | 04/2020 |
| End | 03/2022 |
| Description | HDRUK |
| Amount | £3,003,650 (GBP) |
| Funding ID | NIWA1 |
| Organisation | Health Data Research UK |
| Sector | Private |
| Country | United Kingdom |
| Start | 05/2018 |
| End | 04/2023 |
| Description | HTA grant: : A multi-centre randomised controlled trial of the clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (awarded to Vanessa Raymont) |
| Amount | £1,988,751 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2021 |
| End | 08/2024 |
| Description | Harnessing the power of advanced imaging for dementia diagnosis |
| Amount | $137,461 (USD) |
| Funding ID | AARF-21-846366 |
| Organisation | Alzheimer's Association |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 01/2022 |
| End | 12/2023 |
| Description | High content imaging of iPSC-derived neurons to dissect mechanisms of Parkinson's |
| Amount | £80,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 09/2021 |
| Description | Identifying genetic biomarkers of survival for bowel cancer to aid patient management |
| Amount | £90,000 (GBP) |
| Organisation | Tenovus Cancer Care |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 09/2022 |
| Description | Improving prevention trials in AD through imaging |
| Amount | £249,965 (GBP) |
| Funding ID | 261 (AS-PG-15-025) |
| Organisation | Alzheimer's Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 02/2017 |
| Description | Inflammation in frontotemporal lobar degeneration - from diagnosis and prognosis to clinical trials - Dr M Malpetti |
| Amount | £495,687 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2022 |
| End | 02/2027 |
| Description | Iona Thomas Wright : Departmental Neuroscience DPhil Studentship Understanding the mechanisms of pathological alpha-synuclein cell-to-cell transfer |
| Amount | £75,000 (GBP) |
| Organisation | University of Oxford |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2022 |
| End | 09/2026 |
| Description | JPND |
| Amount | £350,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 05/2019 |
| Description | JPND EUFIND |
| Amount | £30,000 (GBP) |
| Organisation | EU Joint Programme - Neurodegenerative Disease Research (JPND) |
| Sector | Public |
| Country | European Union (EU) |
| Start | 10/2016 |
| End | 10/2017 |
| Description | Johanna Hoffman - Understanding organellar calcium signalling in Parkinson's iPSC-dopamine neurons |
| Amount | £100,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2023 |
| End | 09/2026 |
| Description | Kellogg College Travel Grant |
| Amount | £381 (GBP) |
| Organisation | University of Oxford |
| Department | Kellogg College |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 11/2022 |
| End | 04/2023 |
| Description | Leveraging human genetics to identify target populations for dementia therapeutics (Eisai/DRI), project grant |
| Amount | £200,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2020 |
| End | 02/2023 |
| Description | MIND-MAPS |
| Amount | £977,920 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 03/2020 |
| Description | MJ Fox Therapeutic Pipeline Program: Enhancing autophagy flux in Parkinson's disease |
| Amount | $330,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | |
| Description | MR/T033371/1 - DPUK2 Integrated Dementia Experimental Medicine |
| Amount | £7,670,000 (GBP) |
| Funding ID | MR/T033371/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 12/2025 |
| Description | MRC CASE Award with Biogen (Principal Supervisor to William McGuiness. Molecular mechanisms of TFEB in Parkinson's |
| Amount | £200,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 09/2022 |
| Description | MRC COEN |
| Amount | £150,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2016 |
| End | 06/2018 |
| Description | MRC Momentum Award (Microglial interactions in Alzheimer's Disease) |
| Amount | £4,300,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2017 |
| Description | MRC Momentum Award (Microglial interactions in Alzheimer's Disease-informatics) |
| Amount | £1,000,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | MRC Partnership Award (Dementias Platform UK Stem Cell Partnership) |
| Amount | £1,200,000 (GBP) |
| Funding ID | MR/N013255/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 06/2020 |
| Description | MRC Partnership grant for UK7T |
| Amount | £220,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2019 |
| Description | MRC Project Grant MR/V013599: Identifying the regulation of striatal dopamine function by striatal astrocytes in health and parkinsonism (Prof S Cragg & Prof R Wade-Martins) |
| Amount | £1,038,078 (GBP) |
| Funding ID | MR/V013599 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2021 |
| End | 01/2024 |
| Description | MRC UK Dementia Research Institute Award - Dementia Bench to Bedside |
| Amount | £6,000,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 10/2022 |
| Description | MRC-KHIDI UK-KOREA PARTNERING AWARDS |
| Amount | £100,000 (GBP) |
| Funding ID | MC_PC_18006 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 04/2018 |
| Description | MRC-NIH UK-US Dementia Research Collaboration programme |
| Amount | £11,000 (GBP) |
| Funding ID | MC_PC_17204 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2019 |
| Description | Mapping the Modulatory Landscape Governing Striatal Dopamine Signaling and Its Dysregulation in Parkinson's Disease. |
| Amount | $9,000,000 (USD) |
| Organisation | Aligning Sciences Across Parkinson's |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2021 |
| End | 10/2024 |
| Description | Maria Claudia Caiazza was awarded an ARUK Thames Valley network Pilot Award |
| Amount | £2,500 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 06/2021 |
| Description | Mental Health Pathfinder Award |
| Amount | £1,000,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Michael J Fox Foundation: In depth phenotypic profiling of PINK1/Parkin stem cell-derived neurons and glia.(Prof Wade-Martins) |
| Amount | $600,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 09/2021 |
| End | 02/2023 |
| Description | Michael J Fox Foundation: Transcriptomic changes in iPSC-derived dopaminergic neurons induced by exposure to alpha-synuclein revealed by single cell RNA-Seq. |
| Amount | $200,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 04/2021 |
| End | 09/2022 |
| Description | Michael J Fox Foundation: Validation of FASN as a target for therapeutic development in PD.(Prof Wade-Martins) |
| Amount | $200,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 04/2021 |
| End | 11/2022 |
| Description | Mootaz Salman - Organ-on-a-chip human patient stem cell models of the blood-barrier in Parkinson's disease. |
| Amount | £115,000 (GBP) |
| Organisation | The Leverhulme Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2022 |
| End | 04/2025 |
| Description | NIHR BRC Dementia Theme University of Cambridge |
| Amount | £4,250,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2022 |
| End | 11/2027 |
| Description | NIHR Development and Skills Enhancement Award - Ivan |
| Amount | £34,333 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2021 |
| End | 02/2022 |
| Description | Natalie Connor-Robson Lockey Fund- for travel to World Parkinson's congress |
| Amount | £500 (GBP) |
| Organisation | Lockey Committee |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 06/2019 |
| Description | Natural Sciences and Engineering Research Council of Canada DPhil Scholarship, and Clarendon Award (Co-supervisors to Kaitlyn Cramb Prof. Richard Wade-Martins & Prof Stephanie Cragg ). In vitro iPSC-derived neuronal circuit models of Parkinson's |
| Amount | £117,000 (GBP) |
| Organisation | Natural Sciences and Engineering Research Council of Canada (NSERC) |
| Sector | Public |
| Country | Canada |
| Start | 10/2019 |
| End | 09/2022 |
| Description | New Therapeutics in Alzheimer s Disease (NTAD) - ARUK |
| Amount | £100,000 (GBP) |
| Funding ID | RG89702 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 08/2020 |
| Description | Oxford Biomedical Research Centre (BRC) |
| Amount | £45,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Oxford Medical Sciences Divisions Returning Carer Fund (Tara Caffrey) |
| Amount | £5,000 (GBP) |
| Organisation | University of Oxford |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 02/2017 |
| End | 05/2017 |
| Description | Peter Kilfeather awarded funding to study using spatial transcriptomics to look at SNpc and VTA gene expression on wild-type mice compared to SNCA-OVX mice. |
| Amount | £22,151 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2021 |
| End | 12/2021 |
| Description | Pilot study to develop an instrument to capture broad-ranging neurodevelopmental problems in children with a genetic diagnosis of intellectual disability |
| Amount | £48,502 (GBP) |
| Organisation | Baily Thomas Charitable Fund |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 11/2019 |
| End | 10/2020 |
| Description | Pilot study to develop an instrument to capture broad-ranging neurodevelopmental problems in children with a genetic diagnosis of intellectual disability |
| Amount | £48,502 (GBP) |
| Organisation | Baily Thomas Charitable Fund |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 11/2019 |
| End | 10/2020 |
| Description | Polygenic risk scores for neurodegeneration and Alzheimer's pathophysiology |
| Amount | £951 (GBP) |
| Organisation | UK Dementia Research Institute |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2020 |
| End | 11/2021 |
| Description | Post-COVID cognitive impairment: characterisation and intervention |
| Amount | £380,000 (GBP) |
| Organisation | MQ Mental Health Research |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 11/2022 |
| Description | Post-Doctoral Fellowship (Supervisor to Dr Charmaine Lang): (£210,000; 01/10/19-30/09/21) New molecular targets in Parkinson's disease. |
| Amount | £210,000 (GBP) |
| Organisation | AstraZeneca |
| Sector | Private |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 09/2021 |
| Description | Predicting dementia outcomes using simple, non-invasive assessments: a prospective population-based study |
| Amount | £207,016 (GBP) |
| Funding ID | MR/P001823/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2016 |
| End | 07/2019 |
| Description | Profiling post-translational modifications of histone proteins as a determinant of Parkinson's susceptibility |
| Amount | £232,404 (GBP) |
| Funding ID | G-1502 |
| Organisation | Parkinson's UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 07/2018 |
| Description | Progressive Supranuclear Palsy Association Small Research Grant |
| Amount | £9,279 (GBP) |
| Organisation | Progressive Supranuclear Palsy Association (PSPA) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 11/2022 |
| Description | Rachel Heon-Roberts, Clarendon Fund & Dept of Physiology, Anatomy, & Genetics. Project title: Establishing a model of a-synuclein and amyloid-ß-induced mitochondrial & lysosomal dysfunction in Alzheimer's disease, PD & Lewy Body dementias |
| Amount | £105,000 (GBP) |
| Organisation | University of Oxford |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2021 |
| End | 09/2024 |
| Description | Restoring noradrenergic function to improve apathy in Parkinson s disease to Claire O Callaghan |
| Amount | £49,677 (GBP) |
| Funding ID | RG90797 |
| Organisation | Parkinson's UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2017 |
| End | 07/2018 |
| Description | Rosetrees: Detecting and tracking brain changes in early Alzheimer's Disease |
| Amount | £248,130 (GBP) |
| Funding ID | M668-CD1 |
| Organisation | Rosetrees Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2017 |
| End | 08/2020 |
| Description | SAIL Dementia eCohort |
| Amount | £50,308 (GBP) |
| Organisation | UK Dementia Research Institute |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 08/2021 |
| Description | SRUK winter studentship |
| Amount | € 2,400 (EUR) |
| Organisation | Society of Spanish Researchers in the United Kingdom |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Sanofi/Genzyme: Modulating GBA activity as a Parkinson's disease therapy |
| Amount | £200,000 (GBP) |
| Organisation | Sanofi |
| Department | Genzyme Therapeutics Ltd |
| Sector | Private |
| Country | United Kingdom |
| Start | 11/2016 |
| End | 10/2017 |
| Description | Senior Research Leaders Discretionary Award |
| Amount | £15,000 (GBP) |
| Organisation | Health and Care Research Wales |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2021 |
| End | 03/2022 |
| Description | Senior Research Leaders Discretionary Award |
| Amount | £60,000 (GBP) |
| Funding ID | SRL2022-25-09 |
| Organisation | Health and Care Research Wales |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2022 |
| End | 03/2023 |
| Description | Stefania Guisanni was successful with an ARUK ECR video awards |
| Amount | £320 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2021 |
| End | 12/2021 |
| Description | Stratification of bipolar disorder: Harnessing clinical heterogeneity and genetics shared with other disorders |
| Amount | £310,234 (GBP) |
| Funding ID | 209176 |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2018 |
| End | 06/2022 |
| Description | Stratification of bipolar disorder: Harnessing clinical heterogeneity and genetics shared with other disorders |
| Amount | £310,234 (GBP) |
| Funding ID | Judith Allardyce |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 12/2021 |
| Description | TRanslating Individual Alzheimer GEnetic risk into disease phenotypes [TRIAGE] |
| Amount | € 420,000 (EUR) |
| Organisation | JPND Research |
| Sector | Academic/University |
| Country | Global |
| Start | 05/2020 |
| End | 04/2023 |
| Description | Targeting HDAC4 in Parkinson's disease |
| Amount | £50,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 02/2021 |
| Description | Targeting disease phenotypes in Parkinson's patient iPSC-derived dopamine neurons |
| Amount | £650,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 10/2020 |
| End | 09/2022 |
| Description | The Airwave Health Monitoring Study (AHMS). An Occupational Cohort Study of the British Police Forces |
| Amount | £1,941,097 (GBP) |
| Funding ID | MR/R023484/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2018 |
| End | 04/2023 |
| Description | The UKDRI IPSC Platform to Model Alzheimer's Disease Risk (IPMAR). SA Cowley |
| Amount | £1,770,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2021 |
| End | 12/2023 |
| Description | The development and implementation of polygenic risk algorithms for stratifying individuals for future cognitive decline due to Alzheimer's disease in non-symptomatic and early cognitive impaired subjects |
| Amount | £288,555 (GBP) |
| Funding ID | 104210 |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 02/2020 |
| Description | The physiology of dementia: magnetoencephalographic investigation of brain networks in frontotemporal lobar degeneration and Alzheimer's disease in preparation for experimental medicine studies. |
| Amount | £49,592 (GBP) |
| Funding ID | RG84879 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 09/2017 |
| Description | Transcriptomic changes in iPSC-derived dopaminergic neurons induced by exposure to alpha-synuclein revealed by single cell RNA-Seq. |
| Amount | $200,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 09/2021 |
| End | 02/2023 |
| Description | Transcriptomic changes in iPSC-derived dopaminergic neurons induced by exposure to alpha-synuclein revealed by single cell RNA-Seq. |
| Amount | $200,000 (USD) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 07/2021 |
| End | 02/2023 |
| Description | Travel grant for conference for Bryan Ng |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2020 |
| End | 03/2020 |
| Description | Travel grant for conference for Bryan Ng |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2019 |
| End | 03/2019 |
| Description | Travel grant for conference for Bryan Ng |
| Amount | £300 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2020 |
| End | 03/2020 |
| Description | UKRI Innovation / Rutherford Fund Fellowships at HDR UK |
| Amount | £560,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2018 |
| End | 02/2021 |
| Description | Understanding vulnerability and resistance in Alzheimer's disease |
| Amount | £99,428 (GBP) |
| Organisation | Janssen Biotech, Inc. |
| Sector | Private |
| Country | United States |
| Start | 04/2023 |
| End | 03/2024 |
| Description | Uniting iPSCS and CRISPR/Cas9 screens- a platform to model and interrogate genetic disease in Oxford |
| Amount | £80,000 (GBP) |
| Organisation | University of Edinburgh |
| Department | Institutional Strategic Support Fund |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2017 |
| End | 06/2019 |
| Description | Validating prognostic biomarkers for colorectal cancer and determining their clinical utility |
| Amount | £155,801 (GBP) |
| Organisation | Cancer Research Wales |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 10/2021 |
| Description | WP7 ARUK Pilot Award: "Disentangling contributions of the hippocampus and striatum in efficient memory-guided attention" |
| Amount | £3,990 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2020 |
| End | 08/2020 |
| Description | WP7 EU Innovative Training Network: European School of Network Neuroscience (awarded to Kia Nobre & Mark Woolrich) |
| Amount | € 3,966,875 (EUR) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 10/2019 |
| End | 10/2023 |
| Description | WP7 German Research Foundation Fellowship to Dr Anna-Katharina Bauer (supervisor Kia Nobre) |
| Amount | € 60,000 (EUR) |
| Organisation | German Research Foundation |
| Sector | Charity/Non Profit |
| Country | Germany |
| Start | 09/2019 |
| End | 08/2021 |
| Description | WP7 Marie Sklodowska-Curie Postdoctoral Fellowship to Dr Méadhbh Brosnan (supervisor Kia Nobre) |
| Amount | € 212,934 (EUR) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 09/2019 |
| End | 08/2021 |
| Description | WP7 Oxford-Berlin Collaboration: "Dynamics of memory systems in the brain" (awarded to Kia Nobre) |
| Amount | € 25,000 (EUR) |
| Organisation | University of Oxford |
| Department | Oxford–Berlin Research Partnership |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 12/2020 |
| Description | WP7 Royal Society Newton Advanced Fellowships and Mobility Grants to Dr André Cravo |
| Amount | £60,000 (GBP) |
| Organisation | The Royal Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2019 |
| End | 08/2021 |
| Description | Wales/NI substantive site. HDR UK |
| Amount | £3,003,650 (GBP) |
| Organisation | Health Data Research UK |
| Sector | Private |
| Country | United Kingdom |
| Start | 05/2018 |
| End | 04/2023 |
| Description | Wellcome Centre for Integrative Neuroimaging - extension |
| Amount | £3,101,188 (GBP) |
| Funding ID | 203139/A/16/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2022 |
| End | 04/2024 |
| Description | Wellcome Integrative Neuroimaging Seed funding - £12,000 . Natalie Connor-Robson |
| Amount | £12,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Wellcome Trust Clinical Research Training Fellowship |
| Amount | £174,791 (GBP) |
| Organisation | Wellcome Trust |
| Department | Wellcome Trust Bloomsbury Centre |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2019 |
| Description | Wellcome Trust Clinical Training Fellowship |
| Amount | £174,791 (GBP) |
| Organisation | Wellcome Trust |
| Department | Wellcome Trust Bloomsbury Centre |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2019 |
| Description | Wellcome Trust DPhil Studentship in Neuroscience: Characterisation of a novel GBA-L444P BAC transgenic mouse model of Parkinson's. (Supervisor to Tara Diviney, Co-Supervisor Prof Stephanie Cragg |
| Amount | £104,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2020 |
| End | 09/2023 |
| Description | Weston Brain Institute - Developing blood based biomarkers to detect pre-clinical Alzheimer's disease and predict progression |
| Amount | £329,663 (GBP) |
| Organisation | Weston Brain Institute |
| Sector | Private |
| Country | Canada |
| Start | 12/2020 |
| End | 12/2020 |
| Description | Weston Brain Institute - Developing blood based biomarkers to detect preclinical Alzheimer's disease and predict progression |
| Amount | £329,663 (GBP) |
| Organisation | Weston Brain Institute |
| Sector | Private |
| Country | Canada |
| Start | 01/2018 |
| End | 10/2020 |
| Description | What makes strategic stroke strategic? Multimodal imaging and network methods to predict dementia after strategic stroke |
| Amount | £4,000 (GBP) |
| Organisation | Alzheimer's Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 08/2017 |
| Description | Wolfson Foundation: Ageing Cohort |
| Amount | £887,193 (GBP) |
| Organisation | The Wolfson Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2013 |
| End | 03/2019 |
| Title | Alzheimer's Disease Data Intiative (ADDI) Workbench |
| Description | Development of a proof of concept system for international data platform data sharing and collaboration. The tool is available to other members of the international working group.. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| Impact | Development of technology solutions for data cataloguing, data identification and federated computation that can facilitate greater cross-platform data access and therefore scientific developments. |
| Title | BIOFIND output |
| Description | The JPND BioIND project was led from MRC-CBU, as an international collaboration to standardize and harmonize methods for dementia research. |
| Type Of Material | Physiological assessment or outcome measure |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | Data sharing across sites, the open science methods and a publication pending are outputs related to the validation and recommendations made. The research tool is part of the growing recognition of MEG's potential to transform dementia research, with novel mechanistic insights and trials outcomes, provided that industry-readiness benchmarks can be met. |
| URL | http://www.neurodegenerationresearch.eu/initiatives/annual-calls-for-proposals/closed-calls/brain-im... |
| Title | CRISPR gene editing |
| Description | We have been able to establish CRISPR/Cas9 gene editing in our lab as a result of this project |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2015 |
| Provided To Others? | Yes |
| Impact | We have been able to perform gene editing in iPSC lines. |
| Title | DPUK Data Portal |
| Description | The DPUK Data Portal has been relaunched to include a seamless transition from the DPUK main welcome site into the research infrastructure. The Portal, hosted by Swansea University, now includes openly available metadata on the DPUK cohorts, as well as information on the various parts of the infrastructure, which include: Portal analysis environment powered by virtual desktop infrastructure, imaging platform powered by XNAT, genetic platform created by Digital Health Labs, data linkage possibilities using world-leading matching technology, and a new and easy-to-use application form for researchers to apply for access to data, based on categorised dementia-specific data ontologies. The Portal is now supporting data access applications with dedicated resource to manage this process, and data management based on consultation with other data consortia and the cohorts themselves is underway using novel data management infrastructure (research data appliance based at Swansea University), enabling governance to remain entirely with the data provider and data access permissions to be managed by a central facility. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | The relaunch of the Portal has seen a surge in scientific collaboration in DPUK - for the period November 2017-January 2018, there are 12 live studies on the Portal, all using multiple cohorts and all cross-institution, including internationally-led studies from Maastricht University and the University of Hong Kong. These studies have primarily phenotypic data as their main modality, however we are also seeing the combination of phenotypic, genotypic and imaging data in studies, thus showing the power of a central system for accessing and analysing data from previously disparate sources. Genetics and imaging work packages are also contributing to the studies being supported by DPUK, and the Portal is making data available to specialists in these areas in order for them to derive services for the epidemiological community to make use of data that was previously unobtainable, either due to access difficulties or specialist intervention being necessary. |
| URL | https://portal.dementiasplatform.uk/ |
| Title | DPUK Data Portal Datathon Virtual Desktop |
| Description | Bespoke virtual desktop infrastructure for DPUK Datathons - comprising of dedicated 32GB RAM/4 CPU machines supporting up to 60 concurrent users. Pre-loaded with software such as Stata 16, SPSS, SAS, R, Python (Anaconda), PyCharm, Spyder, Jupyter Notebook, Eclipse, SQL Server Management Studio, Matlab, and Office. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | The dedicated Datathon desktop has allowed us to run 4 DPUK Datathon events across the UK, which have had an international audience of over 150 researchers cumulatively. |
| URL | https://portal.dementiasplatform.uk/ |
| Title | DPUK Imaging Network- Harmonising of Imaging protocols |
| Description | One important aspect of the work of the DPUK Imaging Network is the harmonising and optimising of protocols for image data acquisition, reconstruction, and analysis. This is currently in progress. There is a dedicated website for the MR/PET Partnership, a sub-group within the Imaging Network. The harmonised protocols will appear here once available: https://www.dpuk-mripet.info/ |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Complete harmonisation has yet to be achieved but this should happen in the first half of 2019. |
| Title | DPUK Stem Cell Network iPSC directory resource for researchers |
| Description | Members of the DPUK Stem Cell Network have produced a directory listing over 100 iPSC lines that could be made available to researchers in collaboration with the labs who generated the lines. The directory can be found on the DPUK website. It is available via the DPUK website and contact being made with the lead researcher who generated the lines. |
| Type Of Material | Cell line |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | The Stem Cell Network has published a range of papers using the resource. For an illustrative example please see a recent 2019 paper from the laboratory of Professor Richard Wade- Martins, the lead of the Stem Cell Network. https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz038/5315478 |
| URL | https://www.dementiasplatform.uk/for-researchers/expert-communities-1/stem-cells-network-1/ipsc-reso... |
| Title | Dementia Diagnosis Algorithm for use in primary care, hospital admissions or mortality datasets |
| Description | The researchers from DPUK WP9 used data from ~17,000 UK Biobank participants to identify participants with one or more dementia codes in primary care, hospital admissions or mortality datasets, and compared the coded data to the full-text medical record. Having validated the accuracy of these datasets, they then developed algorithms that can be applied to identify participants with dementia in UK Biobank and other DPUK cohorts. The authors will continue this promising work by investigating sources of potential bias in the data and the generalisability of these findings to older ages and other geographical areas. |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | This is an initial validation study which has proved that the methodology works. Following recent publication of the results (March 2019) the work will be expanded and the findings built-on. |
| Title | Dementias Platform UK: Cognitive Test Directory. |
| Description | Dementias Platform UK: Cognitive Test Directory. Oxford, UK: DPUK; 2019. for use on the DPUK Data Portal |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | Calvin C, et al. Dementias Platform UK: Cognitive Test Directory. Oxford, UK: DPUK; 2019. Downloadable from: https://www.dementiasplatform.uk/for researchers/get-ahead-with-cognitive-test-data-1/cognitive-test-directory |
| URL | https://www.dementiasplatform.uk/for%20researchers/get-ahead-with-cognitive-test-data-1/cognitive-te... |
| Title | Development of an enhanced Cognitive Assessment for UK Biobank |
| Description | A DPUK funded group (WP10) led by Ian Deary in Edinburgh are working closely with UK Biobank to develop an enhanced cognitive assessment, including tests of cognitive function known to be sensitive to ageing. This includes more detailed tests of declarative memory, reasoning and executive function. There are some limitations of the scope for the tests; a brief period of time is allowed for testing to fit with any planned clinical visits for UK Biobank participants and it has to be self-administered on a computer touch screen. The group has produced a report for UK Biobank on the enhanced UK Biobank cognitive assessment and provided their preliminary assessment of the test characteristics. Subject to UK Biobank approval, it is hoped to provide details of the tests on the DPUK website. Preliminary report to UK Biobank is dated 21.09.2017 and is in the process of being updated. |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | There has been a revision of the tests administered in UK Biobank and an improvement in their quality. This means that they are now more informative for investigating the variety and subtlety of cognitive changes seem in both healthy and pathological ageing. |
| Title | Dopamine neuron microfluidics |
| Description | Development of stem cell-derived neuronal culture techniques using microfluidic devices to channel axonal growth. |
| Type Of Material | Model of mechanisms or symptoms - in vitro |
| Provided To Others? | No |
| Impact | Not yet: it is ongoing development |
| Title | Generation of MAPT CRISPR gene edited iPSC lines |
| Description | We have generated 8 QCed MAPT-/- knockout lines on 2 control backgrounds. |
| Type Of Material | Cell line |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | We will use the MAPT-/- iPSC-derived neurons to study the role of MAPT in Parkinson's |
| Title | Generation of SNCA CRISPR gene edited iPSC lines |
| Description | We have generated 3 QCed SNCA-/- knockout lines on control background and isogenic correction of SNCA Triplication patient line (and also knockout) - clones identified by droplet digital PCR, undergoing confirmatory sequencing. |
| Type Of Material | Cell line |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | Generation of SNCA CRISPR gene edited lines will further our work on the role of macrophages and microglia on the uptake/processing/secretion of alpha-synuclein and its role in stimulating the immune response and enable us to interrogate the mechanism for the phagocytosis defect phenotype observed in the SNCA-Triplication macrophages/microglia. |
| Title | High content, high throughput analysis |
| Description | The ability to perform detailed high-throughput analysis of neurons in culture |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | Shared use of best practice in high-throughput analysis using Opera Phenix imager and high-throughout plate readers |
| Title | In vitro electrophysiology |
| Description | Patch-clamp techniques to measure neuronal activity of stem cell-derived neurons |
| Type Of Material | Technology assay or reagent |
| Provided To Others? | No |
| Impact | Analaysis of stem cell-derived neurons: dopamine neurons, cortical neurons, motor neurons and medium spiny neurons |
| Title | Live cell imaging techniques in iPS-derived DA neurons in vitro |
| Description | We have optimised a live cell imaging protocol for the visualisation and measurement of mitochondrial membrane potential in differentiated neurons. |
| Type Of Material | Cell line |
| Provided To Others? | No |
| Impact | The membrane potential-sensing dye TMRM can be used to quantify membrane potential, with increased fluorescence indicating increased membrane potential. |
| Title | Microglia differentiation |
| Description | The ability to generate microglia from human stem cells from dementia patients |
| Type Of Material | Cell line |
| Provided To Others? | No |
| Impact | We will be able to compare the function of microglia generated from patients and from controls |
| Title | PLA in stem cell neurons |
| Description | To enable the detection of a-syn oligomers in stem cell-derived dopamine neurons |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | The detection of a-syn oligomers in stem cell-derived dopamine neurons |
| Title | Pipelines for processing MR data |
| Description | Novel pipelines for processing MR data (in conjunction with DPUK imaging platform) |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | Establish pipelines to process MR data and combine that data in an imaging platform used by other DPUK cohorts |
| Title | Pipelines for processing PET data from PET/MR |
| Description | Creation of novel pipelines for processing PET data from PET/MR |
| Type Of Material | Improvements to research infrastructure |
| Provided To Others? | No |
| Impact | These pipelines allow for improved efficiency and accuracy in the processing of PET data that is received from a PET/MR scanner. |
| Title | RNA-Seq |
| Description | Development of methods for analysis of RNA-Seq |
| Type Of Material | Technology assay or reagent |
| Provided To Others? | No |
| Impact | Understanding of gene expression profiles in selected cell population |
| Title | Target discovery assays |
| Description | Develop target discovery assays using high throughput screens |
| Type Of Material | Technology assay or reagent |
| Provided To Others? | No |
| Impact | New research facilty built for our work |
| Title | iPSC phenotypic screens |
| Description | We have developed an organelle calcium flux assay for high-throughput screening and applied the assay to screen 4000 small molecules in Parkinson's patient iPSC-dervied dopamine neurons. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | We will use the assay to identify new therapeutic targets or novel and or repurposable small molecule therapeutics. |
| Title | Alzhemer's Disease Polygenic Risk Profiling |
| Description | This model used data from the powerful dataset comprising 17 008 cases and 37 154 controls obtained from the International Genomics of Alzheimer's Project (IGAP). Alzheimer's disease (AD) Polygenic risk scores were generated for 3177 cases and 7277 controls (GERAD data) and tested whether the alleles identified to associate with disease in IGAP sample are significantly enriched in the cases relative to the controls in the GERAD sample. The disease prediction accuracy was investigated in a sample of 3049 cases and 1554 controls (for whom APOE genotype data was available) by means of sensitivity, specificity, area under the receiver operating characteristic curve (AUC) and positive and negative predictive values. The best prediction accuracy AUC = 78.2% (95% confidence interval 77-80%) was achieved by a logistic regression model with APOE, the polygenic score, sex and age as predictors. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | This approach is used to create SNP arrays for AD prediction (for research only so far). |
| Title | C-Surv Ontology |
| Description | The C-Surv ontology was finalised for the curation of DPUK Cohort Data. The onotology is comprised of 20 top-level and 140 2nd-level categories and all cohort data are categoried according to these. Standardisation of naming structure is an ongoing programme across all cohorts. Also, harmonisation of a 30-variable minimal dementia-focused dataset and updating of the DPUK Data Portal metadata tools, according to the C-Surv ontology. |
| Type Of Material | Data handling & control |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | Paper has been written, awaiting submission. The model may be adopted by cohorts and other interested parties as the standard for cohort data curation. |
| Title | Cam-CAN |
| Description | Cam-CAN project extended to include subarm of "Cam-CAn Frail" and early dementia participants. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | Extensive applications for data from CC700; Cam-CAN-Frail still in data acquisition phase. |
| Title | Cerebrovascular Diseases Image Databank |
| Description | Cerebrovascular Diseases Image Databank contains brain magnetic resonance & computed tomographic imaging data from patients with cerebrovascular diseases, created by Professor Joanna Wardlaw. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| Impact | Publicly accessible data-bank, improving research results across study groups focused on developing prevention and treatment methods for small vessel diseases, stroke and Alzheimer's disease. |
| URL | https://www.ed.ac.uk/clinical-sciences/edinburgh-imaging/research/themes-and-topics/analysis-and-pro... |
| Title | Clinical Studies Register |
| Description | The Clinical Studies Register is an opt-out database. DPUK manages this database of willing AIRWAVE cohort participants for re-contact in clinical trials. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | The Clinical Studies Register holds approximately 50,000 participant records. The success and learnings of the Clinical Studies Register lead to the development of Great Minds, an opt-in register for participants who are willing to undergo deeper and more frequent geno- and phenotyping to add to their cohort records. |
| URL | https://www.dementiasplatform.uk/our-impact/trails-readiness |
| Title | DPUK 7T data sharing |
| Description | Agreement on data sharing for 7T images using DPUK XNAT platform |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | pending |
| Title | DPUK Genomics portal |
| Description | The DPUK Genetics portal provides a collaborative platform for individuals, DPUK cohorts and the wider research community to share and access research outputs from genetic research. The platform provides two key tools for finding, sharing and analysing genetic data; The Results Registry tool, accessible via the main DPUK web portal, allows searching and uploading of genetic results data. This tool provides a rich set of search tools specific to genetic data and includes visualisation using the popular JBrowse genomic browser. This tool will allow users to share this data. This can be done under secure data transfer agreements if necessary. The second tool is the Genetic Data Browser this is available exclusively within the secure DPUK infrastructure. This will allow users to create cross-cohort comparison studies based on genotypic datasets and linked phenotypic data. This tool provides an interactive dashboard which can pull in phenotypic data and genetic markers from GWAS data and allow users to intuitively explore, combine and export patient cohorts. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | The DPUK Genetics portal, housed on the DPUK platform, allows non bioinformatic-expert users to explore components of genetic data within a secure environment. We have provided access to an international consortium, GERAD, via the DPUK data portal. This is a dataset of over 18,000 cases and controls (detailed in Table 2), as well as over 5,600 samples to date submitted to the EADB, the European AD DNA bank for deciphering the missing heritability of Alzheimer's disease |
| URL | https://portal.dementiasplatform.uk/ |
| Title | DPUK Imaging Platform |
| Description | Brain scan data from the imaging centres across the UK are brought together in the DPUK imaging platform - a database for anonymised brain scans from the cohort studies. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | The DPUK Central XNAT instance allows users to upload, manage and then share their imaging data with the Imaging Hub. The Imaging Hub allows researchers to identify cohorts of images that they wish to access, coordinate the access procedure, and create projects containing approved data for review and analysis. |
| Title | DPUK Re-imaging MRI Database |
| Description | The database contains MRI scans of brain and body together with self-reported health data from computerised questionnaires. The information follows the latest standard protocol in the UK Biobank imaging sub-study. This database relates to Work Package 3 of the DPUK award, relating to the re-imaging project with UK Biobank. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | The collection of data is ongoing with a target of re-imaging 10,000 subjects from the 100,000 UK Biobank participants in their imaging subs-study. This data collection is was financially (partially) supported from the DPUK award and the protocol to establish the repeat imaging protocol were developed by the DPUK research team. The major impact will come when the full dataset is complete and available to DPUK collaborators for analysis and planning of dementia related trials. The main indirect impact is that UK Biobank are now seeking philanthropic funding to extend on this project and increase repeat imaging numbers to ~70,000. These impacts were made possible by the initial imaging fund awarded to Newcastle, which leveraged a further £8M award from the MRC to UKB for whole repeat body imaging. |
| Title | Early Adversity and Dementia Programme |
| Description | This is a DPUK research programme for investigating the impact of early adversity on longitudinal cognitive decline and dementia. Lead by Dr Sarah Bauemeister, a team of 4 analysts work on different statistical and machine-learning models, across multiple cohorts and multi-modal data to investigate this topic. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | One paper submitted to BioRxiv https://www.biorxiv.org/content/10.1101/749077v1 and four pending papers in progress. A DPUK Discovery award and an MRC UK-Korea award were awarded for this programme, and Gates Ventures are funding its continuation through the ADDI interoperability project (scientific use-case). |
| Title | Great Minds |
| Description | An opt-in database of over 2000 participants from UK-based cohorts who are willing to participate in clinical trials and enhance their phenotyping through eg CANTAB online cognitive tests and Mezurio game as a phone application. Some of these may also under genotyping for greater depth of detail. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | A potential phenotypically rich register of pre-symptomatic healthy people with existing cohort data who are ready to engage with experimental studies to help understanding of dementia. Over three-quarters have engaged with regular online cognitive testing. |
| URL | https://www.greatmindsfordementia.uk/ |
| Title | Great Minds CRM recontact platform connects studies with volunteers with specific characteristics |
| Description | The Great Minds CRM platform is the system by which pseudo-anonymised Great Minds registry data is connected to contact and preference information and allows research assistants to invite identified volunteers with approved studies. |
| Type Of Material | Data handling & control |
| Year Produced | 2020 |
| Provided To Others? | No |
| Impact | The pilot stage has allowed research assistants to securely match a study with volunteers with specific characteristics and manage oversee the engagement - whether the participant agree to join, whether the study claimed the volunteer, whether the study is complete etc. |
| Title | Insight46 XNAT database |
| Description | A bespoke database has been designed for the collection of Insight46 data that is run on the XNAT platform. |
| Type Of Material | Database/Collection of data |
| Provided To Others? | No |
| Impact | This bespoke database allows for the collection of all study data in one location. Study data can be easily shared with authorised users and raw data can be easily downloaded for analysis. |
| Title | SAIL Dementia eCohort (SAILDeC) |
| Description | DPUK has funded the creation of the SAIL (Secure Anonymised Information Linkage) Databank Dementia eCohort, known as SAILDeC. A team from the University of Edinburgh, led by Dr Tim Wilkinson and Dr Christian Schnier, have developed a research cohort from routine healthcare records found in the SAIL Databank, a research databank containing routine healthcare and adminstrative records for the Welsh populace. The eCohort is derived from 1.2 million individuals who met the inclusion criteria, and of those, ~130,000 dementia cases throughout the data coverage have been identified. This represents the first UK research-ready disease cohort derived solely from routine healthcare records, which can be analysed in its own right or combined with other rich sources of cohort and routine data. It is thought that the technical components of creating the cohort, in terms of coding and initial analysis, could be the lead for future eCohort generation in other disease fields. These eCohorts could then be analysed within their specific area of science, or combined for a rich multi-morbidity database. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | This is the first disease-specific eCohort of patients to be created from ~20 years of routine healthcare data. It provides a rich dementia-specific resource for episodic progression of patients with initial MCI through to mortality, and every stage in between. The process of creating the cohort can inform the creation of such cohorts from the SAIL source and other routine clinical data sources in many disease areas. |
| Title | iPSC resource for researchers |
| Description | iPSC resources available are listed on DPUK website where they can download iPSC directory provides the opportunity for researchers to formally request over 100 stem cell lines derived from healthy and diseased individuals |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Valuable way for researchers to find out about available resource |
| URL | https://www.dementiasplatform.uk/for-researchers/expert-communities-1/stem-cells-network-1/ipsc-reso... |
| Description | AMYPAD |
| Organisation | Amyloid Imaging to Prevent Alzheimer's Disease |
| Country | European Union (EU) |
| Sector | Public |
| PI Contribution | JMS is UCL lead for AMYPAD at UCL - which has interdependencies with DPUK through EPAD |
| Collaborator Contribution | Design of protocols |
| Impact | Project recently commenced |
| Start Year | 2016 |
| Description | ARUK's DEMON network and DPUK Reach partnership |
| Organisation | Alzheimer's Research UK |
| Department | Alzheimers Research UK, Cambridge |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Dr Sarah Bauermeister sits on ARUK's Deep Dementia Phenotyping ('DEMON') steering group. DEMON is a national network for data science and AI in dementia research - connecting together to work on new analytical solutions for dementia research. |
| Collaborator Contribution | DPUK Reach is a Data Portal and/or ECR online support user group. It supports DEMON's aims by hosting a forum website which allows researchers to discuss cohorts, analyses, codes, statistical approaches, events and more. |
| Impact | DPUK Reach has been launched as a way of DPUK Datathon participants to prepare and carry on for their Data Portal analyses, |
| Start Year | 2019 |
| Description | ASAP SynTau: Alignment and Standardization of Neuroimaging Methods in Atypical Parkinsonism, specifically Synucleinopathies and Tauopathie |
| Organisation | EU Joint Programme - Neurodegenerative Disease Research (JPND) |
| Country | European Union (EU) |
| Sector | Public |
| PI Contribution | This Working Group brings together neuroimaging experts from all over the world to develop a broad, community-based consensus on imaging protocols. These outcomes will help pave the way for the integration of neuroimaging in large and longitudinal multi-centre studies in AP, including therapeutic trials. Meetings, harmonisation of imaging data, workshops, and later data sharing. |
| Collaborator Contribution | Meetings, harmonisation of imaging data, workshops, and later data sharing. |
| Impact | A project initiation report is submitted to JPND. Data sharing agreements are in progress. |
| Start Year | 2016 |
| Description | Abeta functional assays |
| Organisation | University of Oxford |
| Department | Department of Psychiatry |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We have worked to develop improved in vitro analysis odf Abeta function |
| Collaborator Contribution | Collaborative development of assay |
| Impact | Ongoing collaboration |
| Start Year | 2015 |
| Description | Alan Turing Institute Datathon - a collaboration between ATI, Deep and Frequent Phenotyping and DPUK |
| Organisation | Alan Turing Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Data scientists from many different backgrounds combined their expertise to take on dementia in an unusual format for disease research: a three-day datathon. The intensive research event saw teams come together to work on data that is now available in the DPUK Data Portal. The datathon was jointly organised by DPUK, the Deep and Frequent Phenotyping (DFP) study, and the Alan Turing Institute. The DFP pilot study provided the data and the DPUK Data Portal was the means to work with it. Professor Terry Lyons (UOXF Department of Mathematics) is a leading mathematician with innovative contributions to the analysis of multimodal streamed data and methods that have been applied successfully in mental health contexts. He is also a Turing Fellow. With Dr Andrey Kormilitzin (UOXF), he helped to bring the event to fruition. |
| Collaborator Contribution | The Alan Turing Institute hosted and organised the event, and, as the national institute for data science in the UK, was an ideal partner to bring big data specialists to the great challenges in dementia research. Working with the Alan Turing Institute helped to emphasise one of DPUK's core areas of focus: dementia is not just a challenge that psychiatrists or cognitive neuroscientists can solve alone. Data scientists have a hugely important role to play now that we have the data and the DPUK technology available. |
| Impact | The datathon attracted analysts of all stripes, many of whom had not worked with dementia cohort datasets before. Most of the participants were genuinely excited about the data, datathon and the presentations. We are planning on follow up events, perhaps more focussed on each data type at a time. We're hoping to create a community of experts in these particular data and applications of innovative data science methods for Alzheimer's research. This project brings together several modes of information for people with dementia and will likely play a critical role in understanding how to contrast and compare the different perspectives provided by different types of data. |
| Start Year | 2018 |
| Description | BRACE |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | advice and training on genomic data analysis |
| Collaborator Contribution | Investigating the genetic overlap between AD and other diseases or traits using polygenic risk scores in Avon Longitudinal Study of Parents and Children (ALSPAC) |
| Impact | 1. Application of newly developed methodology (MR-Base), which hallows to do rapid high-throughput analysis of potentially interesting traits and environmental exposures. 2. Test for shared genetic susceptibility between AD and early life lipid levels, glycaemic, anthropometric, behavioral and cognitive traits in ALSPAC children |
| Start Year | 2016 |
| Description | BioFIND - JPND |
| Organisation | EU Joint Programme - Neurodegenerative Disease Research (JPND) |
| Country | European Union (EU) |
| Sector | Public |
| PI Contribution | We led the JPND award on the use of MEG in harmonisation and standarisation for Dementia research, bringing together Pharma and Academic partners from ten sites. |
| Collaborator Contribution | Expertise, knowledge sharing, and scoping of future project needs. |
| Impact | A project initiation report is submitted. A new data sharing project has begun across six sites. |
| Start Year | 2016 |
| Description | CLEAR-Huntington's Disease |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provision of MEG-related methods and analysis advice (postdocs involved: Dr Laura Hughes and Dr Ece Kocagoncu). |
| Collaborator Contribution | N/A |
| Impact | Cambridge and UCL collaboration only. |
| Start Year | 2019 |
| Description | Cambridge 7T consortium |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Cognition and Brain Sciences Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Forming the new University-MRC partnership and Cambridge 7T consortium. Full access to new facility for both partners. |
| Collaborator Contribution | Staff allocation for physics support and adjunctive technologies for participant interaction. |
| Impact | Multidisciplinary - dementia, neurology, psychiatry, development and ageing, cognitive neuroscience and physics. New head of 7T department has been recruited. |
| Start Year | 2015 |
| Description | Cambridge Centre for Ageing and Neuroscience |
| Organisation | University of Cambridge |
| Department | Cambridge Neuroscience |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | My research team has received the permission and access to the genetic data of the CamCan cohort with the aim to analyse the genetic data and calculate dementia related PRS for this cohort. |
| Collaborator Contribution | The partners have provided us with the data |
| Impact | not yet |
| Start Year | 2022 |
| Description | Collaboration with Dr Ece Kocagoncu for NTAD (Dr A Jafarian) |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration on data analysis of test-retest data from NTAD. |
| Collaborator Contribution | Availability of NTAD data. |
| Impact | Title: Test-reTest reliability of dynamic casual modelling of resting states MEG data of Alzheimer patients. |
| Start Year | 2022 |
| Description | Collaboration with Dr Nicholas Ashton at the University of Gothenburg |
| Organisation | University of Gothenburg |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | "Synaptic fluid markers in dementia", sharing expertise in field. |
| Collaborator Contribution | "Synaptic fluid markers in dementia", sharing expertise in field. |
| Impact | Advancing biomarker discovery projects. |
| Start Year | 2022 |
| Description | Collaboration with Dr. Gil Rabinovici at the Memory and Aging Center, Department of Neurology, University California San Francisco |
| Organisation | University of California, San Francisco |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Collaboration on project "Tau-PET and domain-specific cognitive decline in Alzheimer's disease", cross fertilization of research expertise. |
| Collaborator Contribution | Hosted Post-Doc Dr M. malpetti for 4 month fellowship at UCSF. |
| Impact | Reasearch paper: Malpetti M, La Joie R, Rabinovici GD. Tau beats amyloid in predicting brain atrophy in Alzheimer's disease: implications for prognosis and clinical trials. 2022, Journal of Nuclear Medicine - doi: 10.2967/jnumed.121.263694 |
| Start Year | 2022 |
| Description | Collaboration with Dr. Gil Rabinovici, Dr. Rik Ossenkoppele, Dr. Victoria Pelak, Dr. Keir Yong and ISTAART PIA for Atypical AD |
| Organisation | University of San Francisco |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Collaboration on project "Clinicopathological Correlates in Posterior Cortical Atrophy" |
| Collaborator Contribution | Hosted Dr M Malpetti (Post-Doc Rowe Group) for 4 month fellowship at UCSF. |
| Impact | Papers in draft & ongoing research activity |
| Start Year | 2022 |
| Description | Collaboration with Dr. Matthias Brendel at the Ludwig Maximilian University of Munich (Germany) and Prof. Pedro Rosa-Neto at the McGill University (Canada) |
| Organisation | Ludwig Maximilian University of Munich (LMU Munich) |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | TSPO PET in tauopathies project, sharing of expertise |
| Collaborator Contribution | TSPO PET in tauopathies project, sharing of expertise |
| Impact | Research advancement |
| Start Year | 2022 |
| Description | Collaboration with Eisai AiM Institute |
| Organisation | Eisai Ltd |
| Department | Eisai Inc |
| Country | United States |
| Sector | Private |
| PI Contribution | Consultancy on Polygenic risk score for clinical trials |
| Collaborator Contribution | We are in the process of negotiations |
| Impact | potentially this collaboration will pay for a time of a postdoctoral researcher |
| Start Year | 2018 |
| Description | Collaboration with European Bioinformatics institute |
| Organisation | EMBL European Bioinformatics Institute (EMBL - EBI) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We plan to provide a software for polygenic risk score calculation and prosess the GWAS summary statistics for all current GWASes available in EBI GWAS catalogue |
| Collaborator Contribution | provide data access to the GWAS catalogue |
| Impact | This collaboration will provide the GWAS processed data to the research community for quick and efficient calculation of polygenic risk score for any disorder (stored in the EBI GWAS catalogue) |
| Start Year | 2019 |
| Description | Collaboration with Ludwig Maximillian University |
| Organisation | Ludwig Maximilian University of Munich (LMU Munich) |
| Department | University Clinic of Munich |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Overlap with group research interests and activiity. Collaboration focuses on ageing and dementia. |
| Collaborator Contribution | Academic expertise. |
| Impact | In progress. |
| Start Year | 2022 |
| Description | Collaboration with Prof. Giuseppe Baselli, Department of Electronics, Information and Bioengineering |
| Organisation | Polytechnic University of Milan |
| Country | Italy |
| Sector | Academic/University |
| PI Contribution | I hosted two students from Prof. Baselli's group (Valentina Bordin and Ilaria Bertani) for their MSc thesis and trained them in neuroimaging analysis methods. |
| Collaborator Contribution | The students contributed to the project (DPUK - Discovery Award 2018 - PI: Ludovica Griffanti) by performing data analysis, presenting a conference poster and writing a journal article. |
| Impact | The collaboration resulted in a poster presentation at the organisation for human brain mapping (OHBM) conference. Title: "Harmonising measures of white matter hyperintensities across sites and studies: impact of training and manual rating in FSL-BIANCA". The scientific journal article is available as preprint and currently under peer-review. Valentina Bordin has ben awarded with a scholarship to fund a PhD in biomedical engineering. Thanks to the skills learnt as part of this project, she is planning focus on assessing the utility of MRI as a marker for evaluating the efficacy of tele-rehabilitation in dementia. |
| Start Year | 2018 |
| Description | Collaboration with Professor Francesco Sardanelli, Dept. of Radiology University of Milan, IRCCS Policlinico San Donato |
| Organisation | IRCCS Policlinico San Donato |
| Country | Italy |
| Sector | Hospitals |
| PI Contribution | I hosted a PhD student from Prof. Sardanelli's group (Dr. Luca Melazzini) and trained him in neuroimaging analysis methods. |
| Collaborator Contribution | The student contributed to the project (DPUK - Discovery Award 2018 - PI: Ludovica Griffanti) by performing data analysis and interpretation, submitting a conference poster and writing a journal article. |
| Impact | The collaboration resulted in an abstract accepted as oral presentation at the European Congress of Radiology (ECR) 2020. "Classifying white matter hyperintensities according to intensity and spatial localisation reveals specific association with cognition". The scientific journal article is under review. Dr. Melazzini submitted his PhD thesis (including work part of this collaboration) and will defend in March 2021. |
| Start Year | 2019 |
| Description | Collaboration with Professor Francesco Sardanelli, Dept. of Radiology University of Milan, IRCCS Policlinico San Donato |
| Organisation | University of Milan |
| Country | Italy |
| Sector | Academic/University |
| PI Contribution | I hosted a PhD student from Prof. Sardanelli's group (Dr. Luca Melazzini) and trained him in neuroimaging analysis methods. |
| Collaborator Contribution | The student contributed to the project (DPUK - Discovery Award 2018 - PI: Ludovica Griffanti) by performing data analysis and interpretation, submitting a conference poster and writing a journal article. |
| Impact | The collaboration resulted in an abstract accepted as oral presentation at the European Congress of Radiology (ECR) 2020. "Classifying white matter hyperintensities according to intensity and spatial localisation reveals specific association with cognition". The scientific journal article is under review. Dr. Melazzini submitted his PhD thesis (including work part of this collaboration) and will defend in March 2021. |
| Start Year | 2019 |
| Description | Confidentiality & Material Transfer Agreements with Apellies Pharmaceuticals, Inc. |
| Organisation | Apellis Pharmaceutical |
| Country | United States |
| Sector | Private |
| PI Contribution | Focussed on the areas of synaptic health and fnction in dementia and neurodegeneration. |
| Collaborator Contribution | As per agreement. |
| Impact | Partnership ongoing, impacts expected in due course. |
| Start Year | 2022 |
| Description | Covid19 Neuroscience Group @7T |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | New program of research into acute and chronic effects of COVID19 on the brain, including respiratory, cognitive and mental health effects Data collection of inpatients, and those recovering, from severe COVID19, and innovations in brain stem neurochemical imaging |
| Collaborator Contribution | Expertise in spectroscopy and respiratory control from the brain Expertise in remote cognitive testing and normative data |
| Impact | Pending publications Conference papers accepted, ISMRN, BNA |
| Start Year | 2020 |
| Description | Covid19 Neuroscience Group @7T |
| Organisation | University of Oxford |
| Department | Oxford Neuroscience |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | New program of research into acute and chronic effects of COVID19 on the brain, including respiratory, cognitive and mental health effects Data collection of inpatients, and those recovering, from severe COVID19, and innovations in brain stem neurochemical imaging |
| Collaborator Contribution | Expertise in spectroscopy and respiratory control from the brain Expertise in remote cognitive testing and normative data |
| Impact | Pending publications Conference papers accepted, ISMRN, BNA |
| Start Year | 2020 |
| Description | DDI and DPUK |
| Organisation | Alzheimer's Research UK |
| Department | UCL Drug Discovery Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | - JG suggested to introduce the two platforms in turn to gain a better idea of the focuses of each. Given that DPUK funding has been renewed for a further five years from July 2020, it was suggested to discuss 'DPUK2' as opposed to the current scientific programme in place. - The DPUK2 Data Portal and Informatics theme will continue into DPUK2. A manuscript describing the Data Portal has been published today on the European Journal of Epidemiology website. The Data Portal provides secure remote access to unprecedented volume and depths of data, hosting 42 population cohort studies and millions of individuals' anonymised information. - DPUK2 will also been involved in precision recruitment to trials through the Trial Delivery Framework - a structure which will allow highly targeted, richly phenoyped, risk-stratified populations to be consented for re-contact to Experimental Medicine (EM) studies. The Trials Delivery Framework aims to support centres to serve wider recruitment to early phase trials (eg Phase 0 to 1b, rather than later), but does not propose completely reinventing current systems - it will be aligning what is already in place and improving their efficiency. - The EM incubator theme in DPUK2 capitalises on the private public partnership success within DPUK1 - it is a cross-industry pool of companies and academics in a pre-competitive space. The focus of the EM Incubator is largely on human trials, asking questions on how we can best validate targets for humans. - DPUK2 industrial partners are highly supportive of the collaborative environment of the platform, enabling them to achieve understanding early on how companies can best move into drug development and use. - Therefore DPUK2 as a whole has an overall focus on translation and experimental studies. The platform would like to put these services to DDI and gain a better understanding on how DPUK can, for example, support discovery molecules being passed on to other entities. |
| Collaborator Contribution | - Please see PowerPoint slide deck '200424 DDA slides for DPUK' for reference - JD described the network of the three DDIs (Oxford, Cambridge, UCL), which overall primarily focus on drug design, synthesis, target ID and validation - screening through to an in vivo Proof of Concept (POC) end point. The institutes sit between academia and industry, with the DDIs often reflecting the interests of the researchers involved. The network aims to take early targets and 'de-risk' them, ahead of passing to industry to develop the drugs further. - The lead molecules isolated by the DDIs are not clinical candidates - it could be up two years of further funding before a reasonable clinical candidate is obtained. However, the DDI network needs to think about translation into humans from the beginning, given that is the target's ultimate aim. - Indeed, although the DDI focuses on producing an in vivo POC endpoint, it is has been clear from the past few years that industrial partners are increasingly looking for the network to provide a blueprint of how these targets can translate into clinic. - The Cambridge DDI has a key focus on proteostasis, with some neuroimmune, neuronal health and vascular research. - The Oxford DDI focuses mostly on neuroimmunity and Alzheimer's Disease, due to the disease's strong genetic component to inform target design. There is also research into organelle dysfunction (mostly in Parkinson's) and some target classes (ligases, kinases etc) - The UCL DDI interests focus on microglia, astrocytes and synaptic health, and takes part in opportunistic research on vascular, mitophagy and b-amyloid questions. A spin-out involving astrocytes (Astronautics) has been successful. There is a strong crossover of research with the Oxford DDI. |
| Impact | - Potential opportunities for collaboration between DDI and DPUK include: - Translational biomarkers ? Target engagement ? Proof of mechanism - Experimental medicine for novel mechanisms - Patient stratification (for novel mechanisms) - Human data to support novel target ID & validation |
| Start Year | 2020 |
| Description | DPUK |
| Organisation | Medical Research Council (MRC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Steering Group member, DPUK work package lead. |
| Collaborator Contribution | Creating Dementia Platform UK Data Portal |
| Impact | In the process of creating on-line database with dementia cohorts, available in the UK and pipelines for data analyses. Multidisceplinary: genetics, bioinfirmatics, IT. |
| Start Year | 2014 |
| Description | DPUK Cambridge |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Optimisation of high-content imaging protocols with Opera Phenix imager |
| Collaborator Contribution | The ARUK Stem Cell Research Centre, Cambridge has standardised the use of the Opera Phenix and Nanostring Sprint instruments for QC in iPSC reprogramming and cproduction of cortical neurons. The Phenix is used for high-throughput imaging of pluripotency markers in patient-derived lines that are generated at the centre. The lab has established a method for routine characterisation of cortical neuron productions using the Nanostring digital gene expression platform. This will facilitate harmonisation of protocols between DPUK centres, and within the STEMBANCC consortium. The imaging platform has been used to develop methods for production of human microglia from iPSCs, and to study cell biology in patient iPSC-derived microglia, focussing on TREM2 mutatiosn. In collaboration with Talisman Therapeutics and AstraZeneca, assays have been established to measure protein uptake in cortical neurons by live imaging. |
| Impact | Development of a strong Dementia Stem Cell Network in DPUK |
| Start Year | 2016 |
| Description | DPUK DSCN |
| Organisation | Cardiff University |
| Department | School of Biosciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Forming DPUK Dementia Stem Cell Network |
| Collaborator Contribution | Forming DPUK Dementia Stem Cell Network |
| Impact | Collaborations and interactions |
| Start Year | 2015 |
| Description | DPUK DSCN |
| Organisation | University College London |
| Department | Medical School |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Forming DPUK Dementia Stem Cell Network |
| Collaborator Contribution | Forming DPUK Dementia Stem Cell Network |
| Impact | Collaborations and interactions |
| Start Year | 2015 |
| Description | DPUK DSCN |
| Organisation | University of Cambridge |
| Department | Gurdon Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Forming DPUK Dementia Stem Cell Network |
| Collaborator Contribution | Forming DPUK Dementia Stem Cell Network |
| Impact | Collaborations and interactions |
| Start Year | 2015 |
| Description | DPUK DSCN |
| Organisation | University of Edinburgh |
| Department | MRC Centre for Regenerative Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Forming DPUK Dementia Stem Cell Network |
| Collaborator Contribution | Forming DPUK Dementia Stem Cell Network |
| Impact | Collaborations and interactions |
| Start Year | 2015 |
| Description | DPUK DSCN |
| Organisation | University of Manchester |
| Department | Manchester Medical School |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Forming DPUK Dementia Stem Cell Network |
| Collaborator Contribution | Forming DPUK Dementia Stem Cell Network |
| Impact | Collaborations and interactions |
| Start Year | 2015 |
| Description | DPUK Data Discovery Tools Categorisation and Coding Programme |
| Organisation | University of Oxford |
| Department | Department of Psychiatry |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provide data from our cohort |
| Collaborator Contribution | Create Data discovery tool |
| Impact | Still ongoing |
| Start Year | 2018 |
| Description | DPUK Imaging Consortium |
| Organisation | MRC Dementias Platform UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Sharing of Imaging protocols and data management structures |
| Collaborator Contribution | N/A |
| Impact | Project recently commenced |
| Start Year | 2016 |
| Description | DPUK Tau Partnership |
| Organisation | Life Molecular Imaging |
| Country | Germany |
| Sector | Private |
| PI Contribution | The partnership involves the use of a novel PET tracer (PI2620) developed by Life Molecular Imaging to carry out Tau PET imaging in existing DPUK cohorts (specifically, the PREVENT AD cohort and the AMYPAD PNHS cohort) |
| Collaborator Contribution | LMI (part of the Alliance Medical Group) brings industry expertise in molecular imaging of degenerative brain disease to the Tau-PET study. This study will benefit from a key investigational compound used for PET imaging which is being developed by LMI. |
| Impact | Collaboration between industry and DPUK (Neurology, Radiology, Nuclear MedicineEpidemiology, Psychiatry). |
| Start Year | 2019 |
| Description | DPUK industry partnership |
| Organisation | Araclon Biotech |
| Country | Spain |
| Sector | Private |
| PI Contribution | The Dementias Platform UK provides a research infrastructure for developing new treatments for dementia |
| Collaborator Contribution | Expertise and technologies |
| Impact | Please refer to the following link: http://brain.oxfordjournals.org/content/138/12/3673 |
| Start Year | 2014 |
| Description | DPUK industry partnership |
| Organisation | AstraZeneca |
| Department | MedImmune |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | The Dementias Platform UK provides a research infrastructure for developing new treatments for dementia |
| Collaborator Contribution | Expertise and technologies |
| Impact | Please refer to the following link: http://brain.oxfordjournals.org/content/138/12/3673 |
| Start Year | 2014 |
| Description | DPUK industry partnership |
| Organisation | GlaxoSmithKline (GSK) |
| Department | Neurology and GI Centre of Excellence for Drug Discovery (CEDD) GSK |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | The Dementias Platform UK provides a research infrastructure for developing new treatments for dementia |
| Collaborator Contribution | Expertise and technologies |
| Impact | Please refer to the following link: http://brain.oxfordjournals.org/content/138/12/3673 |
| Start Year | 2014 |
| Description | DPUK industry partnership |
| Organisation | Ixico |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | The Dementias Platform UK provides a research infrastructure for developing new treatments for dementia |
| Collaborator Contribution | Expertise and technologies |
| Impact | Please refer to the following link: http://brain.oxfordjournals.org/content/138/12/3673 |
| Start Year | 2014 |
| Description | DPUK industry partnership |
| Organisation | Janssen Research & Development |
| Country | Global |
| Sector | Private |
| PI Contribution | The Dementias Platform UK provides a research infrastructure for developing new treatments for dementia |
| Collaborator Contribution | Expertise and technologies |
| Impact | Please refer to the following link: http://brain.oxfordjournals.org/content/138/12/3673 |
| Start Year | 2014 |
| Description | DPUK industry partnership |
| Organisation | SomaLogic |
| Country | United States |
| Sector | Private |
| PI Contribution | The Dementias Platform UK provides a research infrastructure for developing new treatments for dementia |
| Collaborator Contribution | Expertise and technologies |
| Impact | Please refer to the following link: http://brain.oxfordjournals.org/content/138/12/3673 |
| Start Year | 2014 |
| Description | DPUK-2 (2020 - 2023) |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Calculation of pathway specific PRS, relevant to the Neuroinflammation work package. |
| Collaborator Contribution | Access to the DPUK cohorts |
| Impact | data access to DPUK cohorts |
| Start Year | 2020 |
| Description | DSG (Data Study Group) Network |
| Organisation | Alan Turing Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | A joint collaboration with the Turing Institue for using the DPUK Data Portal for Workshop - Machine learning - Data Portal infrastructure across DPUK population cohorts. |
| Collaborator Contribution | Provision of the data workshop infrastructure - DPUK Data Portal and joint hosting of workshop |
| Impact | Newly active March 2019 |
| Start Year | 2019 |
| Description | DSG (Data Study Group) Network |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | A joint collaboration with the Turing Institue for using the DPUK Data Portal for Workshop - Machine learning - Data Portal infrastructure across DPUK population cohorts. |
| Collaborator Contribution | Provision of the data workshop infrastructure - DPUK Data Portal and joint hosting of workshop |
| Impact | Newly active March 2019 |
| Start Year | 2019 |
| Description | Dementias Platform Europe - a collaboration between EMIF-AD and DPUK |
| Organisation | European Medical Information Framework (EMIF) |
| Country | European Union (EU) |
| Sector | Charity/Non Profit |
| PI Contribution | John Gallacher and consultant Prof Derek Hill (advisor to the DPUK1 Executive Team) met with Prof PJ Visser (PI of EMIF) to investigate the possibility of a merger of the two platforms' data and technology, with the support from industry. |
| Collaborator Contribution | Prof Visser hosted the 2-day visit in Amsterdam, providing a tour and in-depth analysis of the runnings and technical features of the EMIF platform. |
| Impact | Prof Derek Hill provided a written report to internal DPUK colleagues on the potential strengths and challenges of merging with EMIF. Industry partners have shown interest in supporting the scheme with funding, with further meetings due to happen in February 2020 to move the initiative forward. |
| Start Year | 2019 |
| Description | Dementias Platform UK Stem Cell Partnership |
| Organisation | MRC Dementias Platform UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | OPDC will share expertise and stem cell lines as part of DPUK Stem Cell Network |
| Collaborator Contribution | Members will share expertise and stem cell lines as part of DPUK Stem Cell Network |
| Impact | Ongoing |
| Start Year | 2016 |
| Description | Dementias Platform UK Stem Cell Partnership |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | OPDC will share expertise and stem cell lines as part of DPUK Stem Cell Network |
| Collaborator Contribution | Members will share expertise and stem cell lines as part of DPUK Stem Cell Network |
| Impact | Ongoing |
| Start Year | 2016 |
| Description | Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease |
| Organisation | McGill University |
| Department | Montreal Neurological Institute and Hospital |
| Country | Canada |
| Sector | Hospitals |
| PI Contribution | Laura Parkkinen and team will analyze CSF samples |
| Collaborator Contribution | Dr Brit Mollenhauer (University of Gottingen); Dr Alex Iranzo (University of Barcelona); Dr Bradley Boeve, (NIH); Dr Ronald Postuma (McGill University); Dr Elena Antelmi (University of Bologna) who all provide us with CSF samples from longitudinally followed RBD patients. |
| Impact | We have received a 2-year project grant entitled "Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease" from PD UK starting from 1st February 2019 |
| Start Year | 2018 |
| Description | Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease |
| Organisation | National Institutes of Health (NIH) |
| Country | United States |
| Sector | Public |
| PI Contribution | Laura Parkkinen and team will analyze CSF samples |
| Collaborator Contribution | Dr Brit Mollenhauer (University of Gottingen); Dr Alex Iranzo (University of Barcelona); Dr Bradley Boeve, (NIH); Dr Ronald Postuma (McGill University); Dr Elena Antelmi (University of Bologna) who all provide us with CSF samples from longitudinally followed RBD patients. |
| Impact | We have received a 2-year project grant entitled "Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease" from PD UK starting from 1st February 2019 |
| Start Year | 2018 |
| Description | Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease |
| Organisation | University of Barcelona |
| Country | Spain |
| Sector | Academic/University |
| PI Contribution | Laura Parkkinen and team will analyze CSF samples |
| Collaborator Contribution | Dr Brit Mollenhauer (University of Gottingen); Dr Alex Iranzo (University of Barcelona); Dr Bradley Boeve, (NIH); Dr Ronald Postuma (McGill University); Dr Elena Antelmi (University of Bologna) who all provide us with CSF samples from longitudinally followed RBD patients. |
| Impact | We have received a 2-year project grant entitled "Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease" from PD UK starting from 1st February 2019 |
| Start Year | 2018 |
| Description | Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease |
| Organisation | University of Bologna |
| Department | Department of Neurologial Sciences |
| Country | Italy |
| Sector | Academic/University |
| PI Contribution | Laura Parkkinen and team will analyze CSF samples |
| Collaborator Contribution | Dr Brit Mollenhauer (University of Gottingen); Dr Alex Iranzo (University of Barcelona); Dr Bradley Boeve, (NIH); Dr Ronald Postuma (McGill University); Dr Elena Antelmi (University of Bologna) who all provide us with CSF samples from longitudinally followed RBD patients. |
| Impact | We have received a 2-year project grant entitled "Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease" from PD UK starting from 1st February 2019 |
| Start Year | 2018 |
| Description | Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease |
| Organisation | University of Göttingen |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Laura Parkkinen and team will analyze CSF samples |
| Collaborator Contribution | Dr Brit Mollenhauer (University of Gottingen); Dr Alex Iranzo (University of Barcelona); Dr Bradley Boeve, (NIH); Dr Ronald Postuma (McGill University); Dr Elena Antelmi (University of Bologna) who all provide us with CSF samples from longitudinally followed RBD patients. |
| Impact | We have received a 2-year project grant entitled "Development of alpha-synuclein seeding assay as an early, progression and stratifying biomarker for Parkinson's disease" from PD UK starting from 1st February 2019 |
| Start Year | 2018 |
| Description | Dr Brent Ryan & Derek Narendra NIH Inherited Movement Disorders Unit, National Institute of Neurological Disorders and Stroke, Bethesda, MD |
| Organisation | National Institutes of Health (NIH) |
| Department | National Institute of Neurological Disorders and Stroke (NINDS) |
| Country | United States |
| Sector | Public |
| PI Contribution | Dr Brent Ryan & Derek Narendra NIH Inherited Movement Disorders Unit, National Institute of Neurological Disorders and Stroke, Bethesda, MD. Scope: Collaboration to assess mitophagy in models of PD |
| Collaborator Contribution | Dr Brent Ryan & Derek Narendra NIH Inherited Movement Disorders Unit, National Institute of Neurological Disorders and Stroke, Bethesda, MD. Scope: Collaboration to assess mitophagy in models of PD Publication: Malpartida AB, Williamson M, Narendra DP, Wade-Martins R, Ryan BJ. Trends Biochem Sci. 2020 Dec 12:S0968-0004(20)30278-4. doi: 10.1016/j.tibs.2020.11.007. Online ahead of print. PMID: 33323315 |
| Impact | Publication: Malpartida AB, Williamson M, Narendra DP, Wade-Martins R, Ryan BJ. Trends Biochem Sci. 2020 Dec 12:S0968-0004(20)30278-4. doi: 10.1016/j.tibs.2020.11.007. Online ahead of print. PMID: 33323315 |
| Start Year | 2020 |
| Description | Dr Brent Ryan & Evandro Fang University of Oslo, Norway Scope: Assessment of mitophagy modulators in iPSC models of PD |
| Organisation | University of Oslo |
| Country | Norway |
| Sector | Academic/University |
| PI Contribution | Dr Brent Ryan collaborating with Evandro Fang University of Oslo, Norway Scope: Assessment of mitophagy modulators in iPSC models of PD Output: Aman Y, Ryan B, Torsetnes SB, Knapskog AB, Watne LO, McEwan WA, Fang EF. Int Rev Neurobiol. 2020;155:169-202. doi: 10.1016/bs.irn.2020.02.008. Epub 2020 Aug 11. PMID: 32854854 |
| Collaborator Contribution | Dr Brent Ryan collaborating with Evandro Fang University of Oslo, Norway Scope: Assessment of mitophagy modulators in iPSC models of PD Output: Aman Y, Ryan B, Torsetnes SB, Knapskog AB, Watne LO, McEwan WA, Fang EF. Int Rev Neurobiol. 2020;155:169-202. doi: 10.1016/bs.irn.2020.02.008. Epub 2020 Aug 11. PMID: 32854854 |
| Impact | Publication: Aman Y, Ryan B, Torsetnes SB, Knapskog AB, Watne LO, McEwan WA, Fang EF. Int Rev Neurobiol. 2020;155:169-202. doi: 10.1016/bs.irn.2020.02.008. Epub 2020 Aug 11. PMID: 32854854 |
| Start Year | 2020 |
| Description | Dr Brent Ryan collaboration with Dr Maria Letizia Lo Faro NDSS |
| Organisation | University of Oxford |
| Department | Nuffield Department of Surgical Sciences Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Dr Maria Letizia Lo Faro (NDSS) to investigate the role of mitophagy in models of organ transplantation initiated in 2022. Grants pending. |
| Collaborator Contribution | Collaboration with Dr Maria Letizia Lo Faro (NDSS) to investigate the role of mitophagy in models of organ transplantation initiated in 2022. Grants pending. |
| Impact | Collaboration with Dr Maria Letizia Lo Faro (NDSS) to investigate the role of mitophagy in models of organ transplantation initiated in 2022. Grants pending. |
| Start Year | 2022 |
| Description | Dr Brent Ryan collaboration with Dr Mark Cookson |
| Organisation | National Institute on Aging |
| Department | Laboratory of Neurogenetics |
| Country | United States |
| Sector | Public |
| PI Contribution | Collaboration with Dr Mark Cookson (National Institute on Aging, USA) initiated in 2022 to share proteomics datasets from patient iPSC-derived cell types including dopaminergic neurons and microglia. Not governed by formal agreements (grants pending). |
| Collaborator Contribution | Collaboration with Dr Mark Cookson (National Institute on Aging, USA) initiated in 2022 to share proteomics datasets from patient iPSC-derived cell types including dopaminergic neurons and microglia. Not governed by formal agreements (grants pending). |
| Impact | n/a |
| Start Year | 2022 |
| Description | Dr Brent Ryan collaboration with Dr Morten Meyer (University of Southern Denmark). |
| Organisation | University of Southern Denmark |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Collaboration with Dr Morten Meyer (University of Southern Denmark). Investigation of RhoA signalling in Parkinson's- student Sissel Ida Schmidt is visiting for 6 months. Publication Okarmus et al 2021. |
| Collaborator Contribution | Investigation of RhoA signalling in Parkinson's- student Sissel Ida Schmidt is visiting for 6 months. Publication Okarmus et al 2021. |
| Impact | Justyna Okarmus, Jesper F. Havelund, Matias Ryding, Sissel I. Schmidt, Helle Bogetofte, Rachel Heon-Roberts, Richard Wade-Martins, Sally A. Cowley, Brent J. Ryan, Nils J. Færgeman, Poul Hyttel, Morten Meyer, Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism, Stem Cell Reports, Volume 16, Issue 6, 2021, Pages 1510-1526, ISSN 2213-6711, https://doi.org/10.1016/j.stemcr.2021.04.022. (https://www.sciencedirect.com/science/article/pii/S2213671121002174) Abstract: Summary PARK2 (parkin) mutations cause early-onset Parkinson's disease (PD). Parkin is an ubiquitin E3 ligase that participates in several cellular functions, including mitochondrial homeostasis. However, the specific metabolomic changes caused by parkin depletion remain unknown. Here, we used isogenic human induced pluripotent stem cells (iPSCs) with and without PARK2 knockout (KO) to investigate the effect of parkin loss of function by comparative metabolomics supplemented with ultrastructural and functional analyses. PARK2 KO neurons displayed increased tricarboxylic acid (TCA) cycle activity, perturbed mitochondrial ultrastructure, ATP depletion, and dysregulation of glycolysis and carnitine metabolism. These perturbations were combined with increased oxidative stress and a decreased anti-oxidative response. Key findings for PARK2 KO cells were confirmed using patient-specific iPSC-derived neurons. Overall, our data describe a unique metabolomic profile associated with parkin dysfunction and show that combining metabolomics with an iPSC-derived dopaminergic neuronal model of PD is a valuable approach to obtain novel insight into the disease pathogenesis. Keywords: Parkinson's disease; parkin; induced pluripotent stem cells; metabolomics; mitochondria; oxidative stress |
| Start Year | 2021 |
| Description | Dr Brent Ryan collaboration with Prof. Martin Rossel Larsen & Dr Helle Bogetofte (University of Southern Denmark) |
| Organisation | University of Southern Denmark |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Collaboration with Prof. Martin Rossel Larsen & Dr Helle Bogetofte (University of Southern Denmark) to perform post-translational proteomics on iPSC-derived neurons generated in Oxford. Not governed by formal agreements (grants pending). |
| Collaborator Contribution | Continuing collaboration with Prof. Martin Rossel Larsen & Dr Helle Bogetofte (University of Southern Denmark) to perform post-translational proteomics on iPSC-derived neurons generated in Oxford. Not governed by formal agreements (grants pending). |
| Impact | n/a |
| Start Year | 2021 |
| Description | EISAI |
| Organisation | Eisai Ltd |
| Department | Eisai Europe Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | we provide expertise and data analysis of pathways and gene networks related to neurodegeneration |
| Collaborator Contribution | The partner provide expertise the the biological definition of neurodegenerative gene networks |
| Impact | NA |
| Start Year | 2019 |
| Description | EMIF-AD and DPUK |
| Organisation | European Medical Information Framework (EMIF) |
| Country | European Union (EU) |
| Sector | Charity/Non Profit |
| PI Contribution | Towards DP Europe: What do we want to achieve? Components and technical aspects COMPONENTS v Catalogue • How to integrate DPUK/EMIF Catalogues? • How to implement direct link to dataset if data are stored on platform? v Subject level data platform with data analysis functions Towards DP Europe: What do we want to achieve? Management, funding & future expansions MANAGEMENT v Interaction cohort owners: UK/Europe/Worldwide v Upload cohort data v Harmonization v Managing data requests v MTA/contracting FUNDING v DP UK v DP Europe (Pharma) FUTURE EXPANSIONS v Human Brain Project Medical Informatic platform v GAAIN • DPUK • DP Europe instance (to be hosted outside UK in Europe) v Platform for harmonized subject-level data on tranSMART v Prepad/Switchbox like access to local database v Common Ontology • Which variables to harmonize? TECHNICAL ASPECTS v Integration v Hosting v Maintenance |
| Collaborator Contribution | Towards DP Europe: What do we want to achieve? Components and technical aspects COMPONENTS v Catalogue • How to integrate DPUK/EMIF Catalogues? • How to implement direct link to dataset if data are stored on platform? v Subject level data platform with data analysis functions Towards DP Europe: What do we want to achieve? Management, funding & future expansions MANAGEMENT v Interaction cohort owners: UK/Europe/Worldwide v Upload cohort data v Harmonization v Managing data requests v MTA/contracting FUNDING v DP UK v DP Europe (Pharma) FUTURE EXPANSIONS v Human Brain Project Medical Informatic platform v GAAIN |
| Impact | Future plans and discussions surrounding the establishment of DPEU. |
| Start Year | 2020 |
| Description | ENIGMA MEG working group |
| Organisation | University of Southern California |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Supply of a dementia and healthy participants dataset. |
| Collaborator Contribution | TBC |
| Impact | A new collaboration in development, initiated late 2020 and the first meeting took place in January 2021. |
| Start Year | 2021 |
| Description | ETH Zurich - Oxford collaboration for functional imaging in a rodent model of Parkinson's disease |
| Organisation | ETH Zurich |
| Country | Switzerland |
| Sector | Academic/University |
| PI Contribution | Richard Wade-Martin's lab has engineered the rodent model of Parkinson's disease (human SCA overexpression). This model has been characterized with histology, voltammetry of dopamine release in cell culture, and behaviourally. In collaboration with the Zurich group, Johannes Klein has performed data analysis on the imaging provided by ETH Zurich. |
| Collaborator Contribution | Oxford does not currently have the ability to perform high-quality resting state MRI in small animals. Our collaboration partners at ETH of acquired the imaging data, performed pre-processing with motion correction and ICA data cleaning. Together, we have analysed differences in brain networks between mice overexpressing human alpha-synuclein, and alpha-synuclein knockout siblings. |
| Impact | The research is ongoing. The imaging data will be published in the coming year. |
| Start Year | 2015 |
| Description | Enhancing autophagy flux in Parkinson's disease |
| Organisation | AstraZeneca |
| Department | Astra Zeneca |
| Country | United States |
| Sector | Private |
| PI Contribution | OPDC test drug like molecules in cellular models of Parkinson's |
| Collaborator Contribution | Astra Zeneca to provide drug-like small molecules. |
| Impact | Ongoing |
| Start Year | 2016 |
| Description | Established collaboration with Ira Milosevic, University of Oxford Wellcome Centre for Human Genetics |
| Organisation | University of Oxford |
| Department | Wellcome Trust Centre for Human Genetics |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | To study synaptic vesicle recycling and STXBP6 biology in our Parkinson's models. Ira will provide the tools and expertise. |
| Collaborator Contribution | The collaboration will be to study synaptic vesicle recycling and STXBP6 biology in our Parkinson's models. Ira will provide tools and expertise |
| Impact | The collaboration will be to study synaptic vesicle recycling and STXBP6 biology in our Parkinson's models. Ira will provide tools and expertise |
| Start Year | 2021 |
| Description | European Prevention of Alzheimers disease project (EPAD) |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | DPUK is contributing towards the trials infrastructure and recruitment tot he EPAD longitudinal cohort study |
| Collaborator Contribution | European colleagues are also contributing towards the trials infrastructure and recruitment tot he EPAD longitudinal cohort study |
| Impact | Multi-disciplinary: clinicians, imagers, geneticists, statisticians, epidemiologists. |
| Start Year | 2016 |
| Description | Evaluation of selected CSF proteins as prognostic markers of dementia in patients with Parkinson's disease |
| Organisation | Oxford University Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provision of samples from our cohort |
| Collaborator Contribution | Measuring two serum proteins (haptoglobin and homocysteine), as well as two cerebrospinal fluid proteins (Aß1-42 and phospho-tau). |
| Impact | Ongoing research |
| Start Year | 2016 |
| Description | Free living walking behaviour in a cohort of people with RBD |
| Organisation | Newcastle University |
| Department | Institute of Neuroscience |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | applying the Axivity Device to RBD and Control participants attending Discovery clinic and providing clinical data |
| Collaborator Contribution | Further analysis of data to look for evidence of the onset of motor-symptoms. |
| Impact | Ongoing research |
| Start Year | 2016 |
| Description | GENFI study - multi centre study |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | NA |
| Collaborator Contribution | NA |
| Impact | NA |
| Start Year | 2016 |
| Description | GR@CE |
| Organisation | Catalan Health Institute (ICS) |
| Country | Spain |
| Sector | Public |
| PI Contribution | we analyse the genome-wide data |
| Collaborator Contribution | the collaborators provided the data to us |
| Impact | it is a multidisciplinary collaboration, involve clinicians, biologists and bioinformaticians |
| Start Year | 2020 |
| Description | GWAIS |
| Organisation | University of Liege |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | We bring our expertise in AI and ML |
| Collaborator Contribution | Collaborators bring their expertise in genetic interaction analyses. |
| Impact | It is a multidisciplinary collaboration involving mathematicians, software developers and bioinformaticians |
| Start Year | 2021 |
| Description | Gothenberg CSF projects |
| Organisation | University of Gothenburg |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Sharing of samples |
| Collaborator Contribution | Assays |
| Impact | A number of papers and also training of laboratory staff |
| Start Year | 2012 |
| Description | Harvard University |
| Organisation | Harvard University |
| Department | Harvard Medical School |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | generation of polygenic risk scores |
| Collaborator Contribution | provision of tissue samples and genotyped data |
| Impact | none yet |
| Start Year | 2019 |
| Description | Hong Kong University of Science and Technology |
| Organisation | The Hong Kong University of Science and Technology |
| Country | Hong Kong |
| Sector | Academic/University |
| PI Contribution | Then HKUST will provide the summary statistics from the previous publication work (DOI: 10.1073/pnas.1715554115) to Cardiff to test if models derived from the Chinese population data can be used for disease classification in the European-descent population. |
| Collaborator Contribution | The Cardiff will provide the models derived from the European population, and HKUST will help to examine if those models can classify AD in the Chinese population. |
| Impact | NA |
| Start Year | 2022 |
| Description | Innovate UK |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Consultancy |
| Collaborator Contribution | Design of Alzhemer's disease chip |
| Impact | In the process of designing of Alzhemer's disease SNP array. Multidisceplinary: medical genetics, bioinformatics, statistics |
| Start Year | 2015 |
| Description | Insight 46 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Cognition and Brain Sciences Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaborating with colleagues at the UCL MRC National Survey for Health and Development, Institute of Molecular Neuroscience, and Institute of Nuclear Medicine, Insight 46 is a major prospective two-time point (0, 12m) MRI, amyloid PET, clinical, biomarker and neuropsychological study of 500 members of the MRC National Survey for Health and Development 1946 birth cohort. This highly inter-disciplinary study involving UCL based epidemiologists, neurologists, imagers, clinical chemists, geneticists and statisticians aims to determine the earliest biomarker changes of AD, the contribution of genetic and life course influences on the development of late life cognitive impairment, and the optimal means of designing AD prevention studies. This >£5M project includes funding from ARUK, MRC Dementias Platform UK (WP4), Wolfson Foundation and Brain Research Trust, as well as industry contributions (~£850K, Eli Lilly). As well as coordinating the project (with Fox, Richards) I supervise a study manager, two clinical PhD students (Lane and Parker, a Wellcome Training Fellowship), and a study coordinator. The study is well underway, with >300 scaned; cross-sectional data will complete in October 2017; and longitudinal collection two years later. |
| Collaborator Contribution | N/A |
| Impact | N/A |
| Start Year | 2014 |
| Description | International Parkinson's Disease genetic Consortium (IPDGC) |
| Organisation | The International Parkinson Disease Genomics Consortium |
| Sector | Academic/University |
| PI Contribution | New collaboration with the International Parkinson's Disease genetic Consortium (IPDGC); single-cell RNA seq studies, spatial transcriptomics, next generation pathology (i.e. developing deep learning algorithms for PD-related pathologies) |
| Collaborator Contribution | New collaboration with the International Parkinson's Disease genetic Consortium (IPDGC); single-cell RNA seq studies, spatial transcriptomics, next generation pathology (i.e. developing deep learning algorithms for PD-related pathologies) |
| Impact | New collaboration with the International Parkinson's Disease genetic Consortium (IPDGC); single-cell RNA seq studies, spatial transcriptomics, next generation pathology (i.e. developing deep learning algorithms for PD-related pathologies) |
| Start Year | 2019 |
| Description | JPND |
| Organisation | JPND Research |
| Country | Global |
| Sector | Academic/University |
| PI Contribution | Joint grant funding and projects |
| Collaborator Contribution | Working with collaborative members on research activities |
| Impact | no |
| Start Year | 2016 |
| Description | JPND EUFIND - European Ultrahigh Field Imaging Biomarkers for Dementia |
| Organisation | EU Joint Programme - Neurodegenerative Disease Research (JPND) |
| Country | European Union (EU) |
| Sector | Public |
| PI Contribution | An international consortium for harmonisation and standardisation of UHF-MRI for Dementia Research. We have contributed expertise, data, and engaged in a pilot study for feasibility and methods development |
| Collaborator Contribution | An international consortium for harmonisation and standardisation of UHF-MRI for Dementia Research. Our partners from 20 EU sites have contributed expertise, data, and engaged in a pilot study for feasibility and methods development |
| Impact | A project initiation report is submitted to JPND |
| Start Year | 2016 |
| Description | Janssen NV Funding Uplift 2018/19 |
| Organisation | Johnson & Johnson |
| Department | Janssen Pharmaceutica |
| Country | Global |
| Sector | Private |
| PI Contribution | DPUK Oxford provide project management and financial management for projects supported as part of this partnership |
| Collaborator Contribution | As well as supporting the project through financial contributions Janssen are actively involved in collaborative research associated with DPUK projects. |
| Impact | Publications arising will be reported by project leads |
| Start Year | 2014 |
| Description | Leuven University |
| Organisation | University of Leuven |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | generation of polygenic risk scores |
| Collaborator Contribution | sharing genotyped data and PRS |
| Impact | none yet |
| Start Year | 2018 |
| Description | Lothian birth cohorts |
| Organisation | University of Edinburgh |
| Department | Edinburgh Neuroscience |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | My research team will analyse the genetic and phenotypic data from the Lothian birth cohorts with the primary aim to investigate genetic of cognitive rate of decline in healthy ageing cohort. |
| Collaborator Contribution | Provided the data. |
| Impact | not yet |
| Start Year | 2022 |
| Description | Lysosomal dysfunction and glycosphingolipid dysregulation in Parkinson's |
| Organisation | University of Oxford |
| Department | Department of Pharmacology |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We have provided serum samples from our cohort |
| Collaborator Contribution | analyse serum/plasma and CSF from PD patients, at--risk patients and control cases as our aims are to characterise the pattern of expression of GSLs in PD and to search for lipid biomarkers |
| Impact | Ongoing research |
| Start Year | 2016 |
| Description | MINDMAPS AD UK |
| Organisation | MRC Dementias Platform UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We are collaborating with Imperial on the Mindmaps project, to combine their UCBJ PET data with our MEG data. The aim is to test the link between synaptic density changes and resting state connectivity in Alzheimer's disease. |
| Collaborator Contribution | Dr Eugenii Rabiner of Invicro, leads MIND MAPS - a collaboration between Invicro, the world's leading neuroscience translational imaging centre, six industry partners (AbbVie, Biogen, Celgene, Hamamatsu Photonics, Pfizer and Takeda) and UK's leading academic centres (King's College, Imperial College, University College, Cambridge, Newcastle). Each partner has contributed their particular expert knowledge. Invicro provided the overall scientific design and cutting edge imaging methodologies, the academic partners contribute disease specific knowledge and expertise in patient selection and care. Industry partners provide the knowledge of promising treatment targets and treatments. The collaboration combines these ingredients to ensure that the techniques being developed and tested by the team are truly fit for purpose to support future disease modifying clinical trials. It demonstrates a collaborative way of working that signposts the future of dementia research. |
| Impact | TBC |
| Start Year | 2017 |
| Description | MRC fellowship |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | advice and training on genomic data analysis |
| Collaborator Contribution | A researcher, Dr. Emma Anderson, who is a highly productive junior researcher |
| Impact | 1. To improve causal inference in mendelian randomization studies of dementia 2. To improve understanding of the genetic risk for dementia and trajectories of cognitive capabilities in aging 3. To identify modifiable risk factors that are related to dementia and cognitive decline |
| Start Year | 2016 |
| Description | Misplaced in space |
| Organisation | University of East Anglia |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Development of PE concept, and data sharing. |
| Collaborator Contribution | Artistic development of a Dementia outreach exhibition |
| Impact | Exhibition in 2017 at the University of East Anglia |
| Start Year | 2016 |
| Description | NTAD Collaboration with UCL-UK DRI Plasma Tau Analysis |
| Organisation | UK Dementia Research Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | NTAD study provides blood samples obtained from participants with Alzheimer's disease. |
| Collaborator Contribution | Collaboration with Dr Henrik Zetterberg & Dr Amanda Heslegrave, UK DRI Fluid Biomarker Laboratory at UCL, for plasma tau analysis obtained from NTAD participants. |
| Impact | TBC |
| Start Year | 2020 |
| Description | NTAD new therapeutics in Alzheimer's disease |
| Organisation | Alzheimer's Research UK |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | DPUK EM theme |
| Collaborator Contribution | New biomarker platform for dementia - Cambridge, Oxford, Janssen, JnJ, Lilly, AZ, ARUK and DPUK - |
| Impact | Annual workshop |
| Start Year | 2017 |
| Description | NTAD new therapeutics in Alzheimer's disease |
| Organisation | AstraZeneca |
| Department | Astra Zeneca |
| Country | United States |
| Sector | Private |
| PI Contribution | DPUK EM theme |
| Collaborator Contribution | New biomarker platform for dementia - Cambridge, Oxford, Janssen, JnJ, Lilly, AZ, ARUK and DPUK - |
| Impact | Annual workshop |
| Start Year | 2017 |
| Description | NTAD new therapeutics in Alzheimer's disease |
| Organisation | Eli Lilly & Company Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | DPUK EM theme |
| Collaborator Contribution | New biomarker platform for dementia - Cambridge, Oxford, Janssen, JnJ, Lilly, AZ, ARUK and DPUK - |
| Impact | Annual workshop |
| Start Year | 2017 |
| Description | NTAD new therapeutics in Alzheimer's disease |
| Organisation | Johnson & Johnson |
| Department | Janssen Pharmaceuticals |
| Country | United States |
| Sector | Private |
| PI Contribution | DPUK EM theme |
| Collaborator Contribution | New biomarker platform for dementia - Cambridge, Oxford, Janssen, JnJ, Lilly, AZ, ARUK and DPUK - |
| Impact | Annual workshop |
| Start Year | 2017 |
| Description | NTAD new therapeutics in Alzheimer's disease |
| Organisation | Oxford University Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | DPUK EM theme |
| Collaborator Contribution | New biomarker platform for dementia - Cambridge, Oxford, Janssen, JnJ, Lilly, AZ, ARUK and DPUK - |
| Impact | Annual workshop |
| Start Year | 2017 |
| Description | NTAD new therapeutics in Alzheimer's disease |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | DPUK EM theme |
| Collaborator Contribution | New biomarker platform for dementia - Cambridge, Oxford, Janssen, JnJ, Lilly, AZ, ARUK and DPUK - |
| Impact | Annual workshop |
| Start Year | 2017 |
| Description | National Institutes of Health Oxford-Cambridge Scholars Programme (NIH-OxCam) for Stewart Humble |
| Organisation | National Institutes of Health (NIH) |
| Country | United States |
| Sector | Public |
| PI Contribution | NIH OxCam programme, a doctoral training programme for medical students to continue their education in biomedical research at either Oxford or Cambridge University in partnership with the National Institutes of Health (NIH) in Washington DC. (PI: Michael Ward, NIH; Co-supervisor: Wade-Martins; 01/10/16-30/09/20) Molecular mechanisms of progranulin in FTD |
| Collaborator Contribution | NIH OxCam programme, a doctoral training programme for medical students to continue their education in biomedical research at either Oxford or Cambridge University in partnership with the National Institutes of Health (NIH) in Washington DC. (PI: Michael Ward, NIH; Co-supervisor: Wade-Martins; 01/10/16-30/09/20) Molecular mechanisms of progranulin in FTD |
| Impact | NIH OxCam programme, a doctoral training programme for medical students to continue their education in biomedical research at either Oxford or Cambridge University in partnership with the National Institutes of Health (NIH) in Washington DC. (PI: Michael Ward, NIH; Co-supervisor: Wade-Martins; 01/10/16-30/09/20) Molecular mechanisms of progranulin in FTD |
| Start Year | 2016 |
| Description | Neurochip Task Force Genetics Study |
| Organisation | German Centre for Neurodegenerative Diseases |
| Country | Germany |
| Sector | Public |
| PI Contribution | All study members to genotype their cohort on same chip |
| Collaborator Contribution | Sharing genomic data between cohorts with OPDC and Centre PD |
| Impact | Still active |
| Start Year | 2018 |
| Description | Neurochip Task Force Genetics Study |
| Organisation | University of Luxembourg |
| Department | Faculty of Science, Technology and Communication |
| Country | Luxembourg |
| Sector | Academic/University |
| PI Contribution | All study members to genotype their cohort on same chip |
| Collaborator Contribution | Sharing genomic data between cohorts with OPDC and Centre PD |
| Impact | Still active |
| Start Year | 2018 |
| Description | ODDI Phenotypic drug discovery in Parkinson's |
| Organisation | University of Oxford |
| Department | Alzheimer's Research UK Oxford Drug Discovery Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Collaborative drug discovery project in Parkinson's |
| Collaborator Contribution | Collaborative drug discovery project in Parkinson's |
| Impact | Ongoing |
| Start Year | 2017 |
| Description | Ongoing collaboration between Dr A Jafarain (Rowe Group) and Prof. Karl Firston (UCL) |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contributions to the development of Multimodal Dynamic Causal Modelling for projects in translational neuroscience and dementia. |
| Collaborator Contribution | Professional expertise and collaboration sought. |
| Impact | Jafarian, A., Hughes, L.E., Adams, N.E., Lanskey, J., Naessens, M., Rouse, M.A., Murley, A.G., Friston, K.J. and Rowe, J.B., 2022. Neurochemistry-enriched dynamic causal models of magnetoencephalography, using magnetic resonance spectroscopy. bioRxiv, pp.2022-06. |
| Start Year | 2020 |
| Description | Oxford collaboration for molecular imaging (PET) in a rodent model of Parkinson's disease. |
| Organisation | University of Oxford |
| Department | Department of Oncology |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Richard Wade-Martins' lab has engineered rodent models of Parkinson's disease: LRRK2 BAC transgenic rats expressing human wild-type, G2019S, or R1441C LRRK2 mutations. These models have been extensively characterised using behavioural tests, voltammetry, electrophysiological recordings and immunohistochemistry analyses, showing that transgenic rats aged 18-21 months bearing any of the LRRK2 mutations exhibit L-DOPA responsive motor dysfunction, impaired striatal dopamine release, and cognitive deficits, but with no apparent neurodegeneration or protein accumulation on histology. In collaboration with the Imaging Core at the Oncology Department, we have optimised a scanning protocol for the aged rat-cohorts that will allow the acquisition of 18F-DOPA PET data to further characterise the effect of these mutations on dopamine metabolism, and validate these rodent models for future imaging studies. The aim is to provide early imaging readouts for the response to therapy with candidate compounds in an animal model of the early stages of PD. |
| Collaborator Contribution | This collaboration allows us to bring new methods to OPDC. Our collaborators provide the radiotracers needed to perform our molecular imaging studies (fluorodopa is not routinely produced or distributed), and the facilities and expertise to run our scans. Veronique Gouverneur's lab has pioneered a new synthesis route for fluorodopa, and they are currently working to scale it up to production level for us. Sean Smart and Veerle Kersemans run the PET facility at the Oncology Department and have optimised the imaging logistics, and helped with acquisition protocols and data reconstruction so we are able to scan our aging cohorts in time. |
| Impact | Initial pilot studies have been performed to detect and address imaging-specific problems before starting the analysis of the transgenic cohorts. The dose and injection timing of aromatic amino acid decarboxylase (AADC) and catechol-O-methyltransferase (COMT) inhibitors (benserazide and entacapone respectively), have been optimised to avoid fluorodopa metabolism outside the brain. The dose of radiotracer and scanning timings are currently under investigation with further pilot scans. We will start imaging the transgenic cohorts at the beginning of 2018, and we anticipate to complete data acquisition and analysis by the end of the year. With the outputs generated from this research, we will be able to apply for further funding to advance our use of molecular imaging for model characterisation and, in the future, for studies evaluating promising candidate compounds to modify disease progression. |
| Start Year | 2016 |
| Description | Oxford collaboration for molecular imaging (PET) in a rodent model of Parkinson's disease. |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Richard Wade-Martins' lab has engineered rodent models of Parkinson's disease: LRRK2 BAC transgenic rats expressing human wild-type, G2019S, or R1441C LRRK2 mutations. These models have been extensively characterised using behavioural tests, voltammetry, electrophysiological recordings and immunohistochemistry analyses, showing that transgenic rats aged 18-21 months bearing any of the LRRK2 mutations exhibit L-DOPA responsive motor dysfunction, impaired striatal dopamine release, and cognitive deficits, but with no apparent neurodegeneration or protein accumulation on histology. In collaboration with the Imaging Core at the Oncology Department, we have optimised a scanning protocol for the aged rat-cohorts that will allow the acquisition of 18F-DOPA PET data to further characterise the effect of these mutations on dopamine metabolism, and validate these rodent models for future imaging studies. The aim is to provide early imaging readouts for the response to therapy with candidate compounds in an animal model of the early stages of PD. |
| Collaborator Contribution | This collaboration allows us to bring new methods to OPDC. Our collaborators provide the radiotracers needed to perform our molecular imaging studies (fluorodopa is not routinely produced or distributed), and the facilities and expertise to run our scans. Veronique Gouverneur's lab has pioneered a new synthesis route for fluorodopa, and they are currently working to scale it up to production level for us. Sean Smart and Veerle Kersemans run the PET facility at the Oncology Department and have optimised the imaging logistics, and helped with acquisition protocols and data reconstruction so we are able to scan our aging cohorts in time. |
| Impact | Initial pilot studies have been performed to detect and address imaging-specific problems before starting the analysis of the transgenic cohorts. The dose and injection timing of aromatic amino acid decarboxylase (AADC) and catechol-O-methyltransferase (COMT) inhibitors (benserazide and entacapone respectively), have been optimised to avoid fluorodopa metabolism outside the brain. The dose of radiotracer and scanning timings are currently under investigation with further pilot scans. We will start imaging the transgenic cohorts at the beginning of 2018, and we anticipate to complete data acquisition and analysis by the end of the year. With the outputs generated from this research, we will be able to apply for further funding to advance our use of molecular imaging for model characterisation and, in the future, for studies evaluating promising candidate compounds to modify disease progression. |
| Start Year | 2016 |
| Description | PREVENT 7T |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Application of 7T technology to understand the effects of inherited risk of dementia |
| Collaborator Contribution | Coordination of national PREVENT study of people at risk of dementia |
| Impact | Pending |
| Start Year | 2019 |
| Description | PROTECT / CHARIOT-Pro / Cardiff DPUK |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Genotyping of 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be completed by Cardiff Univ as part of a collaboration funded by Dementias Platform UK. Polygenic risk scores will be calculated for these individuals and data made available via DPUK Platform. |
| Collaborator Contribution | DNA samples from 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be sent to Cardiff Univ for genotyping |
| Impact | None to date - work in progress. Collaboration is multi-disciplinary - Neurology, Neuroepidemiology & Ageing; Genetics & Genomics; Psychiatry |
| Start Year | 2018 |
| Description | PROTECT / CHARIOT-Pro / Cardiff DPUK |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Genotyping of 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be completed by Cardiff Univ as part of a collaboration funded by Dementias Platform UK. Polygenic risk scores will be calculated for these individuals and data made available via DPUK Platform. |
| Collaborator Contribution | DNA samples from 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be sent to Cardiff Univ for genotyping |
| Impact | None to date - work in progress. Collaboration is multi-disciplinary - Neurology, Neuroepidemiology & Ageing; Genetics & Genomics; Psychiatry |
| Start Year | 2018 |
| Description | PROTECT / CHARIOT-Pro / Cardiff DPUK |
| Organisation | University of Exeter |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Genotyping of 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be completed by Cardiff Univ as part of a collaboration funded by Dementias Platform UK. Polygenic risk scores will be calculated for these individuals and data made available via DPUK Platform. |
| Collaborator Contribution | DNA samples from 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be sent to Cardiff Univ for genotyping |
| Impact | None to date - work in progress. Collaboration is multi-disciplinary - Neurology, Neuroepidemiology & Ageing; Genetics & Genomics; Psychiatry |
| Start Year | 2018 |
| Description | PSP network |
| Organisation | Cardiff University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | A new netwrok to coordinate clinical and genetic and imaging research of this severe neurodegenerative disorder |
| Collaborator Contribution | 1. coordinated recruitment 2. biomarker development |
| Impact | PPI acivities; Papers pending; |
| Start Year | 2015 |
| Description | PSP network |
| Organisation | Progressive Supranuclear Palsy Association (PSPA) |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | A new netwrok to coordinate clinical and genetic and imaging research of this severe neurodegenerative disorder |
| Collaborator Contribution | 1. coordinated recruitment 2. biomarker development |
| Impact | PPI acivities; Papers pending; |
| Start Year | 2015 |
| Description | PSP network |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | A new netwrok to coordinate clinical and genetic and imaging research of this severe neurodegenerative disorder |
| Collaborator Contribution | 1. coordinated recruitment 2. biomarker development |
| Impact | PPI acivities; Papers pending; |
| Start Year | 2015 |
| Description | PSP network |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | A new netwrok to coordinate clinical and genetic and imaging research of this severe neurodegenerative disorder |
| Collaborator Contribution | 1. coordinated recruitment 2. biomarker development |
| Impact | PPI acivities; Papers pending; |
| Start Year | 2015 |
| Description | PSP network |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | A new netwrok to coordinate clinical and genetic and imaging research of this severe neurodegenerative disorder |
| Collaborator Contribution | 1. coordinated recruitment 2. biomarker development |
| Impact | PPI acivities; Papers pending; |
| Start Year | 2015 |
| Description | R4VAD |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | A DPUK meeting Oxford in January 2016 RE: stem cells, models and human studies lead to applications to TSA/BHF/AS Vascular Dementia call resulting in the 3 funded projects, one of them being Human (R4VAD), with Prof Joana Wardlaw leading c£1.2M. |
| Collaborator Contribution | Leadership on the project and academic expertise. |
| Impact | Too early to report significant outputs or outcomes at present. |
| Start Year | 2016 |
| Description | Rodent fMRI imaging |
| Organisation | ETH Zurich |
| Country | Switzerland |
| Sector | Academic/University |
| PI Contribution | OPDC provides mouse models of Parkinson's |
| Collaborator Contribution | ETH carries out fMRI scanning on mice |
| Impact | Ongoing project |
| Start Year | 2016 |
| Description | SerCymru Fellowship |
| Organisation | Government of Wales |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Supervising a Research Fellow. Project title: Deconvoluting the dementia phenotype using functional genomics and computational approaches |
| Collaborator Contribution | Funding the project |
| Impact | This is a multidisciplinary collaboration between biological sciences and informatics/statistic. We have gained assess to EBI data resources which will be analyzed within the scope of the project. |
| Start Year | 2017 |
| Description | Socio-economic variations in care home admission and health care utilisation in people with dementia living in Wale |
| Organisation | Swansea University |
| Department | Swansea University Medical School |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We have constructed a dementia cohort using Welsh routinely-collected healthcare data. We are providing our expertise and intellectual input on a study being run by researchers at the University of Liverpool on socioeconomic variations in care home admission for people with dementia. |
| Collaborator Contribution | Swansea University - access to data, expertise, intellectual input University of Liverpool - project management, expertise, intellectual input |
| Impact | No outputs or outcomes yet. Collaboration is multidisciplinary: medicine, data science, epidemiology |
| Start Year | 2018 |
| Description | Socio-economic variations in care home admission and health care utilisation in people with dementia living in Wale |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We have constructed a dementia cohort using Welsh routinely-collected healthcare data. We are providing our expertise and intellectual input on a study being run by researchers at the University of Liverpool on socioeconomic variations in care home admission for people with dementia. |
| Collaborator Contribution | Swansea University - access to data, expertise, intellectual input University of Liverpool - project management, expertise, intellectual input |
| Impact | No outputs or outcomes yet. Collaboration is multidisciplinary: medicine, data science, epidemiology |
| Start Year | 2018 |
| Description | Stanford University |
| Organisation | Stanford University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | generation of polygenic risk scores |
| Collaborator Contribution | sharing genotyped data and PRS |
| Impact | none yet |
| Start Year | 2019 |
| Description | Structural and functional connectivity in the human basal ganglia in health and disease using high resolution MRI at 7T |
| Organisation | University of Oxford |
| Department | Nuffield Department of Clinical Neurosciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | FMRIB scans and clinical data from our cohort |
| Collaborator Contribution | Investigate in vivo connectivity of human basal ganglia. |
| Impact | Ongoing research |
| Start Year | 2016 |
| Description | Swansea Datathon - a collaboration between SU, DPUK, Alan Turing Insitute and ARUK |
| Organisation | Swansea University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Direct contributions - DPUK provided £2000 of funding to Swansea University to support the venue and catering arrangements for a three-day datathon, as well as circa £3500 in travel bursaries to ECR attendees. In-kind contributions - DPUK provided the DPUK Data Portal equipment for analysis, technical team support pre-, during and post-event; organisational support (in legal agreements etc) and a Communications team to promote the event widely and regularly keep in touch with attendees. DPUK provided scientific guidance in relation to the host (University of Swansea's) scientific questions that they wanted to answer, based on the cohort data held in the DPUK Data Portal. |
| Collaborator Contribution | Swansea provided scientific leadership and expertise in the questions to be answered in the datathon, as well as equivalent organisational and communications support. With our funding, Exeter sourced a venue and catering. They provided on-ground administrative support on the day, and an important sign-posting role in case of any local queries (eg IT support). |
| Impact | By the end of the three-day event, the near 30 attendees would have broken the back of an innovative analysis which they conceived of and developed in their teams. They will be in a great position to take successful ideas forward to publication stage. They will have gained valuable multi-modal analysis experience working in the Data Portal, with an option to develop their work from the datathon. Swansea University will have gained publicity of their cutting edge work into data science, as well as found a supportive future collaborator and adviser in DPUK. DPUK will have taken a step forward in realising its mission to harness the power of cohort data to fight dementia. DPUK had a real mix of skills and a wide range of experience at this Autumn 2019 DPUK datathon. |
| Start Year | 2019 |
| Description | Synaptic Health |
| Organisation | Alzheimer's Research UK |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | AstraZeneca |
| Department | MedImmune |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | Cardiff University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | Eli Lilly & Company Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | Janssen Biotech, Inc. |
| Country | United States |
| Sector | Private |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | MRC Dementias Platform UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | University of Exeter |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | University of Glasgow |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Synaptic Health |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Academic leadership and skills in new Dementia research platform; planning and applying for new funding; several meeting and phone conferences; about to initiate NTAD in Cambridge; planning of NTAD study; |
| Collaborator Contribution | Expertise in translational neuroscience; planning; meetings; application for further funding; |
| Impact | New Therapeutics in Dementia consortium; an interdisciplinary research group of clinicians, cognitive scientists, informatics, pharmaceutical and drug development experts; phase 0 studies for "New Therapeutics in Alzheimer's Disease" and "Deep and Frequent Phenotyping" that are designed to optimise phase II studies of disease modifying therapies and additional opportunities for insights into disease pathogenesis; data collection, analyses and publications still pending; |
| Start Year | 2015 |
| Description | Syracuse University |
| Organisation | Syracuse University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | still under negotiation |
| Collaborator Contribution | data analysis consultancy |
| Impact | none yet |
| Start Year | 2019 |
| Description | T cell reactivity to alpha-synuclein |
| Organisation | Bristol-Myers Squibb |
| Department | Celgene |
| Country | United States |
| Sector | Private |
| PI Contribution | Interaction with Celgene scientists on Parkinson's immuniology |
| Collaborator Contribution | Mentorship of early career researcher |
| Impact | New post-doc appointed |
| Start Year | 2019 |
| Description | T-cell activation in Parkinson's |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Analysis of response of Parkinson's patient PBMCs to stimulation by alpha-synuclein |
| Collaborator Contribution | Advice on growth and culture of PBMC and how to measure T-cell activation by ELISpot |
| Impact | Collaboration is multi-disciplinary between molecular genetics (Wade-Martins lab) and our partner immunology lab. No outcomes yet. |
| Start Year | 2019 |
| Description | The Deep Dementia Phenotyping (DEMON) Network - committee member (SB) and strategic partner (DPUK JG and SB) |
| Organisation | Alan Turing Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Knowledge partner and network activities associated with the DPUK Datathons and DPUK Usergroup |
| Collaborator Contribution | Provision of resources at DPUK Datathons |
| Impact | Newly established March 2019 |
| Start Year | 2019 |
| Description | The Deep Dementia Phenotyping (DEMON) Network - committee member (SB) and strategic partner (DPUK JG and SB) |
| Organisation | University of Exeter |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Knowledge partner and network activities associated with the DPUK Datathons and DPUK Usergroup |
| Collaborator Contribution | Provision of resources at DPUK Datathons |
| Impact | Newly established March 2019 |
| Start Year | 2019 |
| Description | The genetic background of REM sleep behaviour disorder and its conversion to synucleinopathies. |
| Organisation | McGill University |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Providing DNA samples from our cohort |
| Collaborator Contribution | Analsying with 2 plaforms using advanced genetic methods.They have already analysed about 500 RBD patients, 600 PD patients and about 1000 controls, with very encouraging results. |
| Impact | Ongoing research |
| Start Year | 2017 |
| Description | True Colours Platform Gastroenterology Group |
| Organisation | University of Oxford |
| Department | Department of Psychiatry |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Setting up a collaborative project investigating gastroentestinal disease using the Data Portal as a data sharing platform and collaborative analysis space for gastroenterology. |
| Collaborator Contribution | Analytical expertise and Data Management (Data Portal) |
| Impact | Publiciation written, pending submission. |
| Start Year | 2019 |
| Description | Twinning: Centre PD |
| Organisation | University of Luxembourg |
| Department | Faculty of Science, Technology and Communication |
| Country | Luxembourg |
| Sector | Academic/University |
| PI Contribution | OPDC will share information on clinical cohorts, stem cells and neuropathology |
| Collaborator Contribution | Centre PD will share information on clinical cohorts, stem cells and neuropathology Centre PD worked with us on the EU Twinning grant to facilitate OPDC clinical data base move from Open Clinica to Red Cap System |
| Impact | Ongoing |
| Start Year | 2015 |
| Description | UC Irvine |
| Organisation | University of California, Irvine |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | generation of polygenic risk scores |
| Collaborator Contribution | sharing genotyped data and PRS |
| Impact | none yet |
| Start Year | 2019 |
| Description | UK 7T MRI network |
| Organisation | Cardiff University |
| Department | Brain Research Imaging Centre (CUBRIC) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | establishing a new 7T imaging network, with new CRI funding and MRC Parntership grant. Updated input for 2019 - 2020 - Dr Rodgers (Cambridge Head of 7T MRI Physics) was elected coordinator of the UK7T network from 1 Nov 2019 onwards. |
| Collaborator Contribution | establishing a new 7T imaging network, with new CRI funding |
| Impact | A series of workshops and symposia, for training, education and research exchange. Topics include 7T-Safety, fMRI, Parallel Transmit and research updates. The project is multi-disciplinary, between clinicians in neurology, psychiatry, radiology and physicists, engineers, and data informaticians. |
| Start Year | 2016 |
| Description | UK 7T MRI network |
| Organisation | University of Glasgow |
| Department | Institute of Neuroscience and Psychology |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | establishing a new 7T imaging network, with new CRI funding and MRC Parntership grant. Updated input for 2019 - 2020 - Dr Rodgers (Cambridge Head of 7T MRI Physics) was elected coordinator of the UK7T network from 1 Nov 2019 onwards. |
| Collaborator Contribution | establishing a new 7T imaging network, with new CRI funding |
| Impact | A series of workshops and symposia, for training, education and research exchange. Topics include 7T-Safety, fMRI, Parallel Transmit and research updates. The project is multi-disciplinary, between clinicians in neurology, psychiatry, radiology and physicists, engineers, and data informaticians. |
| Start Year | 2016 |
| Description | UK 7T MRI network |
| Organisation | University of Nottingham |
| Department | School of Biomedical Sciences Nottingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | establishing a new 7T imaging network, with new CRI funding and MRC Parntership grant. Updated input for 2019 - 2020 - Dr Rodgers (Cambridge Head of 7T MRI Physics) was elected coordinator of the UK7T network from 1 Nov 2019 onwards. |
| Collaborator Contribution | establishing a new 7T imaging network, with new CRI funding |
| Impact | A series of workshops and symposia, for training, education and research exchange. Topics include 7T-Safety, fMRI, Parallel Transmit and research updates. The project is multi-disciplinary, between clinicians in neurology, psychiatry, radiology and physicists, engineers, and data informaticians. |
| Start Year | 2016 |
| Description | UK 7T MRI network |
| Organisation | University of Oxford |
| Department | Oxford Centre for Functional MRI of the Brain (FMRIB) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | establishing a new 7T imaging network, with new CRI funding and MRC Parntership grant. Updated input for 2019 - 2020 - Dr Rodgers (Cambridge Head of 7T MRI Physics) was elected coordinator of the UK7T network from 1 Nov 2019 onwards. |
| Collaborator Contribution | establishing a new 7T imaging network, with new CRI funding |
| Impact | A series of workshops and symposia, for training, education and research exchange. Topics include 7T-Safety, fMRI, Parallel Transmit and research updates. The project is multi-disciplinary, between clinicians in neurology, psychiatry, radiology and physicists, engineers, and data informaticians. |
| Start Year | 2016 |
| Description | UK DRI and DPUK |
| Organisation | UK Dementia Research Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | DPUK's strengths lie in data management, precision recruitment, and human studies. |
| Collaborator Contribution | UK DRI offers large groups of scientists looking at mechanisms of diseases and models, and was thinking of moving into more translational work - getting data from clinical studies to generate better scientific questions, and seeing whether UK DRI prediction models translated into human science. The institute can also help identify interests (eg drug lines) for industry. |
| Impact | DPUK presentation to UK DRI scientists as introduction Meetings between UK DRI and DPUK PDRAs for scientific collaboration especially on EM themes in common. Establishment of working group, with a small number of PIs involved (genetic researchers, phenotypic researchers, clinicians cohort owners), to create a UK genetic consortium which aims to improve the study of gene-phenotype correlations for Alzheimer's Disease. |
| Start Year | 2020 |
| Description | UKCRIS collaboration with OHDSI |
| Organisation | Observational Health Data Sciences and Informatics |
| Sector | Charity/Non Profit |
| PI Contribution | The UKCRIS network comprises 11 NHS Trusts across the UK. This collaboration led to the development of an Information Governance agreement to underpin the operation of a federated access model, avhieving data harmonisation with access to 2.2m de identied health records. UKCRIS is now registered as a member of the OHDSI community and has its data model catalogued on the OHDSI portal. |
| Collaborator Contribution | We worked with the EMIF data team to define an approach to mapping the CRIS dataset to the OMOP clinical data model |
| Impact | Information Governance agreement for Federated data access |
| Start Year | 2017 |
| Description | University of East Anglia Datathon - a collaboration between UEA, DPUK, Alan Turing Insitute and ARUK |
| Organisation | University of East Anglia |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | DPUK provided £2000 of funding to UEA to support the venue and catering arrangements for a three-day datathon. DPUK also provided the DPUK Data Portal equipment for analysis, technical team support pre-, during and post-event; organisational support (in legal agreements etc) and a Communications team to promote the event widely and regularly keep in touch with attendees. DPUK provided scientific guidance in relation to the host (UEA's) scientific questions that they wanted to answer, based on the cohort data held in the DPUK Data Portal. |
| Collaborator Contribution | University of East Anglia provided scientific leadership and expertise in the questions to be answered in the datathon, as well as equivalent organisational and communications support. With our funding, UEA sourced a venue and catering. They provided on-ground administrative support on the day, and an important sign-posting role in case of any local queries (eg IT support). In contrast to other datathons, UEA's event was on a larger scale, and they provided a tour of the grounds and art galleries, jazz entertainment throughout the generous after-workshop dinners as well as accommodation for the majority of attendees. |
| Impact | By the end of the three-day event, the near 60 attendees would have broken the back of an innovative analysis which they conceived of and developed in their teams. They will be in a great position to take successful ideas forward to publication stage. They will have gained valuable multi-modal analysis experience working in the Data Portal, with an option to develop their work from the datathon. The UEA will have gained publicity of their cutting edge work into dementia, as well as found a supportive future collaborator and adviser in DPUK. DPUK will have taken a step forward in realising its mission to harness the power of cohort data to fight dementia. |
| Start Year | 2019 |
| Description | University of Exeter Datathon - a collaboration between UoE, DPUK, Alan Turing Insitute and ARUK |
| Organisation | University of Exeter |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | DPUK provided £2000 of funding to the University of Exeter to support the venue and catering arrangements for a three-day datathon. DPUK also provided the DPUK Data Portal equipment for analysis, technical team support pre-, during and post-event; organisational support (in legal agreements etc) and a Communications team to promote the event widely and regularly keep in touch with attendees. DPUK provided scientific guidance in relation to the host (University of Exeter's) scientific questions that they wanted to answer, based on the cohort data held in the DPUK Data Portal. |
| Collaborator Contribution | University of Exeter provided scientific leadership and expertise in the questions to be answered in the datathon, as well as equivalent organisational and communications support. With our funding, Exeter sourced a venue and catering. They provided on-ground administrative support on the day, and an important sign-posting role in case of any local queries (eg IT support). |
| Impact | By the end of the three-day event, the near 30 attendees would have broken the back of an innovative analysis which they conceived of and developed in their teams. They will be in a great position to take successful ideas forward to publication stage. They will have gained valuable multi-modal analysis experience working in the Data Portal, with an option to develop their work from the datathon. The University of Exeter will have gained publicity of their cutting edge work into dementia, as well as found a supportive future collaborator and adviser in DPUK. DPUK will have taken a step forward in realising its mission to harness the power of cohort data to fight dementia. |
| Start Year | 2019 |
| Description | WIN MRI group for imaging mice Natalie Connor-Robson |
| Organisation | Wellcome Trust |
| Department | Wellcome Trust Cente for Neuroimaging |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | WIN MRI group for imaging mice Natalie Connor-Robson |
| Collaborator Contribution | WIN MRI group for imaging mice Natalie Connor-Robson |
| Impact | WIN MRI group for imaging mice Natalie Connor-Robson |
| Start Year | 2019 |
| Title | Biomarker evaluation of 7T MRI in dementia |
| Description | evaluation of novel 7T MRI for early detection of pathology in AD, and other dementias, building on the JPND consortium "EUFIND" |
| Type | Diagnostic Tool - Imaging |
| Current Stage Of Development | Early clinical assessment |
| Year Development Stage Completed | 2020 |
| Development Status | Under active development/distribution |
| Impact | stronger links to basic cognitive neurosciences of memory systems, and to multi-centre clinical transnational centres across EU |
| Title | Expert adviser in planning of a Dementia Centre |
| Description | John was asked as expert to comment on an introductory paper on providing up-market, purpose-built centres to satisfy the increasing demand for treating and caring for all those affected by dementia. The proposed centres are also for the families of sufferers, helping them to cope with the changes in their loved ones, becoming, not just passive carers, but positive forces for minimising rates of decline whilst maximising dignity. |
| Type | Therapeutic Intervention - Psychological/Behavioural |
| Current Stage Of Development | Initial development |
| Year Development Stage Completed | 2020 |
| Development Status | Under active development/distribution |
| Impact | This concept will be further developed with the input of experts like John Gallacher in both care design and treatment with the aim to inform the first Planning Application by Spring 2020. |
| Title | CANTAB remote testing implementation |
| Description | DPUK's partnership with Cambridge Cognition has lead to their CANTAB software being promoted as an application throughout the platform. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2018 |
| Impact | DPUK cohorts are able to request access to CANTAB cognitive testing software to enhance their study. CANTAB software is also used with the Deep and Frequent Phenotyping (DFP, WP16) as part of the phenotyping and the Great Minds database. |
| URL | https://www.cambridgecognition.com/products/cognitive-research/ |
| Title | DPUK Data Portal Cohort Explorer |
| Description | The Cohort Explorer is a tool to conduct exploratory analyses over harmonised data sets. The purpose of the Explorer is to complement the Cohort Matrix and Directory, and gives a visual representation of participant numbers per variable, per cohort, aiding users looking into the eligibility of cohorts they are interested in to shape their potential hypotheses. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2018 |
| Impact | It has helped attendees at DPUK datathons to identify interesting cohorts suitable for their research questions. It has provided researchers the ability to quickly assess demographic information of cohorts before applying for cohort study data through the DPUK Data Portal. |
| URL | https://portal.dementiasplatform.uk/CohortExplorer |
| Title | DPUK Reach |
| Description | The concept for DPUK Reach is to fill the gap in support for researchers accessing the DPUK Data Portal, a lot of researchers are lost following their initial set up but then left to their own devices, many have issues and problems that need resolving and could easily be met by simple peer support rather than costly and time consuming support from the Data Portal team. This will be addressed by using an online forum based approach - DPUK Reach. One of Oxford's DPUK team members is on the working group for DEMON (a network launched by ARUK) and will use their knowledge to support DPUK Reach, and the aim is for both forums will work in collaboration. One of DPUK Data Portal's primary functions is to be a remotely accessed secure analysis environment, with access, pending project application, to large cohort datasets. DPUK Reach will grant enormous research potential to teams of researchers around the world. Having an online area where researchers and ECR's can remotely discuss projects or issues with industry experts and one another, would be invaluable. As science starts to take a modern turn towards online collaborations, more and more digital data is being collected and machine learning and other advanced statistical analysis used. An environment where researchers can brainstorm and receive almost instant advice and support will not only alleviate pressure on the internal DPUK & Data Portal teams, and help to pave the way forward to curing dementia. DPUK Reach will be available to all researchers using the DPUK Data Portal, with a general conversation FAQ area for potential Data Portal users and a restricted area for researchers using the portal, there will also be closed areas that can be used for collaborations such as Datathon participants, to share information about their event and get them collaborating from the outset. All users will need to complete a simple sign in. The DPUK Reach forum will be hosted by Oxford and embedded on the DPUK website and linked from the Data Portal website, a login will be required. Following initial ideas to have Discourse embedded in the Data Portal, DPUK Reach will now use Vanilla Forums hosted by Mythic Beasts on the DPUK website with links from the Data Portal site. Approach DPUK Reach will be a forum embedded within the DPUK website, it will be accessed via registration log in for users, enabling the regulation of users as DPUK Reach will require an agreement to code of conduct. This will enable the forum to be used for the purpose intended and monitoring control. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2020 |
| Impact | Aims • To create a single point of reference for researchers to gain support and knowledge not only with technical Data Portal support, user & cohort information but in other relevant areas such as funding, support for grant applications, interviews, big data sets, population cohorts and statistical support. • To create a secure space for collaborative work among researchers. • To set up and run a research focused and informative support community based around DPUK and the Data Portal. Desired outcomes Short term outcomes: • Set up a forum called DPUK Reach via the DPUK website, with links from Data Portal webpages. • DPUK Reach will be set up to contain separate discussion areas which will host conversations moderated by DPUK staff, in their respective fields. • The forum will be branded according to DPUK's strict branding style guide in order to link in seamlessly with the existing DPUK & Data Portal websites. • To be soft launched at the UEA Datathon, following main launch in November 2019, in line with DEMON Network & EDON • To be fully GDPR compliant; but able to contact users for future DPUK opportunities, events or workshops. Longer term outcomes: • A fully public/private facing forum, with the options to sign up as a user depending on user level need: public, researcher, industry, funder, cohort etc. • Multiple rooms and categories for desired topics (to be continually monitored and expanded over time) • The ability to promote and arrange workshops • To expand affiliation with existing research focused user-groups • To have a fully functioning community of researchers, moderated by users overseen by DPUK staff and centralised around the DPUK website. • To grow the number of DPUK Reach users and successful research projects in the Data Portal by promoting at conferences and talks • To support ECR's with guidance in a variety of areas such as grant applications and interviewing techniques. |
| URL | https://reach.dementiasplatform.uk/entry/signin?Target=categories |
| Title | Dementia's Platform UK Biostatistics Tool |
| Description | Bespoke analysis tool to perform the latest analyses on the largest UK datasets available. |
| Type Of Technology | Software |
| Year Produced | 2016 |
| Impact | Product still under development / improvement following user feedback. |
| Title | Dementia's Platform UK Cohort Selection Tool |
| Description | Used to select cohorts of interest, and to put a research proposal to them for feedback under the DPUK research protocol. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2016 |
| Impact | Improvements ongoing to develop impacts. |
| URL | http://www.dementiasplatform.uk/cohort-tools/ |
| Title | Dementias Platform UK Data Portal |
| Description | The DPUK Data Portal is a platform to allow the ingress of data from cohort studies and real-world evidence data from across the UK and internationally. The Portal allows access, subject to data provider approval, to said data via an integrated application system, and provides an analysis environment on remote desktop to allow distributed team science from anywhere in the world. The Portal environment comprises of front end user tools, a virtual desktop infrastructure for data analysis, a security system for permissions management and data upload, and an underlying architecture of substantial storage and applications to support the data needs. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2017 |
| Impact | To date (early 2019) we have had ~80 applications for cohort data via our new processes. Of these, 50 have been approved and at least 25 studies are underway with analysis of their approved cohort data. All of these studies are contributing to the dementia research community with a mixture of traditional epidemiological hypotheses, methodology validation, complex machine learning, and statistical modelling all being achieved in the Portal. Website: https://portal.dementiasplatform.uk |
| Title | EMD: Empirical Mode Decomposition |
| Description | Python tools for the extraction and analysis of non-linear and non-stationary oscillatory signals. |
| Type Of Technology | Software |
| Year Produced | 2019 |
| Open Source License? | Yes |
| Impact | Features - Sift algorithms including the ensemble sift, complete ensemble sift and mask sift Instantaneous phase, frequency and amplitude computation - Cycle detection and analysis - Hilbert-Huang spectrum estimation (1d frequency spectrum or 2d time-frequency spectrum) - Second layer sift to quantify structure in amplitude modulations - Holospectrum estimation (3d instantaneous frequency x amplitude modulation frequency x time spectrum) |
| URL | https://emd.readthedocs.io/en/latest/ |
| Title | Effective |
| Description | We have developed a novel approach to account for multiple testing in genome-wide association studies as published in (Moskvina and Schmidt, 2008). The software is C++ code, which can be compiled for any computational platform (Windows, Unix, Linux). |
| Type Of Technology | Software |
| Year Produced | 2008 |
| Open Source License? | Yes |
| Impact | The software was requested from the authors more than 10 times since the paper was published. We have made it now publicly available. |
| URL | http://github.com/DRI-Cardiff/Keffective |
| Title | Great Minds participation selection tool |
| Description | We have a pilot participation selection tool that allows research assistants to match registry volunteers to approved study characteristics. It helps the Great Minds team manage requests for study volunteers, against participant preferences and potential fatigue from study requests. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2020 |
| Impact | The participation tool is at the heart of the process for approving and managing studies interest in volunteers and linking these with potential volunteers. |
| Title | Great Minds study feasibility tool |
| Description | The pilot feasibility tool allows researchers to check how many Great Minds registry volunteers have characteristics they seek for their study. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2020 |
| Impact | The pilot feasibility tool allows remote researchers to conduct an exploratory selection of volunteers based on specific criteria. The purpose of the toois to give a visual representation of participant numbers per variable. |
| Title | Mezurio app |
| Description | he Mezurio app lets you complete interactive, scientifically valuable measurement tasks. It's designed to be used as part of a research study. It helps you become an even more valuable part of that research by letting you contribute new kinds of data: quickly, frequently, and from the comfort of your own home. To use this app, simply download it, then tap-in the invite code you were given by your research coordinator, or received by email. At the moment it is only possible to use this app if you are part of an approved, ethically reviewed research study. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2019 |
| Impact | Ivan Koychev (DPUK Clinician Scientist) has been instrumental in the development and dissemination of the Mezurio app, especially in its use in Great Minds and Deep and Frequent Phenotyping. |
| URL | https://www.greatmindsfordementia.uk/ |
| Title | OHBA Software Library development |
| Description | ongoing development of software library for MEEG data analysis. NTAD has led to the development of additional data preprocessing functionality and pipelines in Matlab |
| Type Of Technology | Software |
| Year Produced | 2019 |
| Impact | ongoing development of software library for MEEG data analysis. NTAD has led to the development of additional data preprocessing functionality and pipelines in Matlab |
| URL | https://ohba-analysis.github.io/osl-docs/ |
| Title | Ongoing development and support of data processing and analysis pipelines |
| Description | Ongoing development and support of data processing and analysis pipelines, including: 1. OHBA Software Library - https://ohba-analysis.github.io/osl-docs/ 2. HMM-MAR toolbox - https://github.com/OHBA-analysis/HMM-MAR 3. EMD toolbox - https://emd.readthedocs.io/en/latest/ 4. glmtools toolbox - https://pypi.org/project/glmtools/ |
| Type Of Technology | Software |
| Year Produced | 2021 |
| Impact | Provides tools for fast batch processing of large M/EEG datasets. |
| Title | POLARIS |
| Description | We developed a novel approach to genetic set-based analysis and polygenic risk scoring, which accounts for linkage disequilibrium between SNPs and informs the analysis with previously reported effect sizes of a SNP's association to disease. We call this method POLARIS: POlygenic Linkage disequilibrium-Adjusted RIsk Score. |
| Type Of Technology | Software |
| Year Produced | 2017 |
| Open Source License? | Yes |
| Impact | NA |
| URL | https://github.com/BakerEA/POLARIS |
| Title | glmtools python software development |
| Description | A novel software tool for defining and fitting general linear models on very large datasets in python. First public release 17/7/20 https://pypi.org/project/glmtools/ |
| Type Of Technology | Software |
| Year Produced | 2019 |
| Impact | • glmtools python software development - a novel software tool for defining and fitting general linear models on very large datasets in python |
| Description | "Clinical VCI" Plenary I Keynote, VasCog 2021 Virtual 11th International Conference of the VasCog Society, 8th September 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | "The Funny Side of Parkinson's" |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | "The Funny Side of Parkinson's" on BBC1. Paul Mayhew-Archer Documentary. Richard Wade-Martins and Fahd Baig appeared to talk about OPDC. Paul was named best presenter at the Grierson Awards for this documentary. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.bbc.co.uk/iplayer/episode/b072xkcz/inside-out-south-parkinsons-the-funny-side |
| Description | "The Motor Side of the FTD Spectrum" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Delivered talk to a mixed audience on the motor side of the FTD spectrum. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://wfneurology.org/public/downloads/p9XPX/WCN-2021-Timetable-at-a-glance-Virtual-Congress-26.8.... |
| Description | #DementiaActionWeek2018 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Sharing content to promote #DementiaActionWeek2018 including producing original video of researcher |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://twitter.com/WadeMartinsLab/status/999632001920651264 |
| Description | 'Update on Small Vessel Disease mechanisms and clinical features'. The Tianfu International Stroke Conference 2021, Keynote. 29-30th May 2021 (Virtual/Mianyang, China) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virutal meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | 'What does the scientific evidence mean to the public?' World Stroke Organisation Stroke Prevention Webinar: Prevention of Stroke and Dementia, Virtual, and online, 17 Aug 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | (Dr Kocagoncu) Alzheimer's Association International Conference 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Yujing Huang, Maria-Prats-Sedano, John O'Brien, Ece Kocagoncu, Richard N Henson, James B Rowe, & Li Su (2020). Increased electromagnetic variability in Lewy body dementia: A MILOS study. Alzheimer's Association International Conference 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://alz-journals.onlinelibrary.wiley.com/loi/15525279/year/2020 |
| Description | (Dr Negin Holland) AD/PD conference - March 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Title of Dr Holland's oral presentation: - Disease severity alters the relationship between in vivo synaptic density and tau accumulation in Progressive Supranuclear Palsy |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://cslide.ctimeetingtech.com/adpd21/attendee/confcal/persons/H |
| Description | (Dr Negin Holland) ARUK Conference - March 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Title of Dr Holland's poster: - In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.alzheimersresearchuk.org/research/for-researchers/research-conference-2021/scientific-pr... |
| Description | (Dr Negin Holland) Association of British Neurologist annual conference - May 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Title of the poster presented by Dr Holland: Reduced synaptic density in primary tauopathies, revealed by [11C]UCB-J PET. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.theabn.org/page/virtual_meeting_2020 |
| Description | (Dr Quinn) NeuroMatch Online Conference Oct 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Quinn, A.J., Green, G.G.R, Hymers, M. (Oct 2020). Delineating single subject oscillatory brain networks with Spatio-Spectral Eigenmodes. NeuroMatch online conference. https://www.youtube.com/watch?v=ZN5On6Hb92Y |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.youtube.com/watch?v=ZN5On6Hb92Y |
| Description | 11/5/18 - Swansea University HDR UK & NHS Digital Data Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Discussion to enable mutual understanding List of areas to explore for improvement & areas for development |
| Year(s) Of Engagement Activity | 2018 |
| Description | 11th UK-Korea Neuroscience Symposium - Busan, Korea |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | An invited oral presentation of a paper co-authored with John Gallacher describing a DPUK cross-cohort analysis utilising multiple DPUK cohorts. An additional poster was also presented. The research was titled: 'Using the power of Dementias Platform UK (DPUK) cohorts to investigate the effects of childhood adversity on adult behvaioural, physiological, cognitive and dementia outcomes: A cross-cohort investigation'. Questions and further discussions about the analysis and DPUK were initiated as a result of both presentation and network opportunities are to be followed up from these presentations. Furthermore, interest in the DPUK portal was initiated. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.ukorea.ac.uk/events/11th-uk-korea-neuroscience-symposium-20th-21st-august-2018-haeundae-... |
| Description | 17/06/2020 - Public Health Research at HDRUK. International Scientific Advisory Board |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Public Health Research at HDRUK. International Scientific Advisory Board, 17/06/20. |
| Year(s) Of Engagement Activity | 2020 |
| Description | 1946 70th birthday event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | The 70th Birthday Event celebrated the 70th birthday of participants in the MRC NSHD (1946 birth cohort) - we provided a display of brain imaging |
| Year(s) Of Engagement Activity | 2016 |
| Description | 2/10/18 - Technology Sector Symposium - Developing a UK Wide Health Data Research Platform |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The primary aim of the symposium is to brief potential platform partners on the DIH programme and interest them in the opportunity to work with us to develop it. This will be achieved by: • Informing the technology sector of the aims of the Digital Innovation Hub programme as part of the Industrial Strategy Challenge Fund • Establishing the mutual benefits to patients, the NHS, researchers and innovators • Welcoming industry participation in co-development of the research platform • Defining key requirements for successful delivery of the Digital Innovation Hub platform • Facilitating collaboration across industry/academia/NHS to support this delivery |
| Year(s) Of Engagement Activity | 2018 |
| Description | 2017 Research Dementia Research Day |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Talk to present progress and development in the DPUK and how the Platform can create opportunity. |
| Year(s) Of Engagement Activity | 2015,2017 |
| Description | 2018 article published on iPS research in Oxford in Phenotype (Oxford Biochemical society magazine) |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | A decade of IPS cell research in Oxford by Sally Cowley Phenotype is the magazine of the Oxford University Biochemical Society. It is run by students and staff and published on a termly basis. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://issuu.com/phenotypejournal/docs/mt18 |
| Description | 2018/19 OPDC Newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | We produced a newsletter on OPDC activities. This was sent to all study participants, those on OPDC news mailing list and will be handed out at events. |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/opdc2018-19-newsletter.pdf |
| Description | 21/01/2021 - Data Science and Population Health Research. University of British Columbia, Canada |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Data Science and Population Health Research. University of British Columbia, Canada, 21/01/21. |
| Year(s) Of Engagement Activity | 2021 |
| Description | 23rd National Dementia Conference: Talk on "Frontotemporal Dementia" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | An update on FTD landscape and research output from Rowe group. |
| Year(s) Of Engagement Activity | 2021 |
| Description | 26 April 2016, DPUK Annual Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK Open Day |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.dementiasplatform.uk/wp-content/uploads/2016/06/Conference-Programme.pdf |
| Description | 28/01/2020 Big Data and Public Health. Sandra Macara BMA Memorial Lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | PRESENTATION TO BIG DATA AND PUBLIC HEALTH, SANDRA MACARA MEMORIAL LECTURE IN CARDIFF |
| Year(s) Of Engagement Activity | 2020 |
| Description | 29-30/5/18 - International Clinical Phenomics Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | International, expert workshop, hosted by UK Biobank, to discuss the challenges of accurate identification and sub-phenotyping of multiple health-related outcomes at scale in large population-based prospective studies. |
| Year(s) Of Engagement Activity | 2018 |
| Description | 5-7 October 2016, CCNA ISAB (Vancouver)(premanifest disease & cognitive footprint?) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Plenary lecture at Canadian consortium on Neurodegeneration and aging |
| Year(s) Of Engagement Activity | 2016 |
| Description | 5/9/18 - Design Thinking Workshop |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | As we develop the blueprint for the platform components of the Digital Innovation Hub programme, a one day design workshop as an opportunity for us to focus on the research experience we would ideally like from this platform. A highly interactive session led by experienced design thinking practitioners. |
| Year(s) Of Engagement Activity | 2018 |
| Description | 6-7 April 2016, DZNE (Bonn)"The role of genetic cohorts in bridging clinical and basic science" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Discussion of the role of Genetic cohorts to advise the German Neurodegenerative disease research network |
| Year(s) Of Engagement Activity | 2016 |
| Description | @dementiasuk twitter account |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Our twitter account is used primarily to promote DPUK opportunities (training, funding and resources) amongst the dementia research community, and to engage with current issues in dementia research. |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018 |
| URL | https://twitter.com/DementiasUK |
| Description | A formal working group, expert panel or dialogue - DPUK Annual Conference 2018: The power of cohorts 23 April 2018 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attended one-day conference on using DPUK platform. |
| Year(s) Of Engagement Activity | 2018 |
| Description | A moving target? Dementia in changing older populations (and a changing world) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | A talk was given at AAIC 2016 (Alzheimer's Association International Conference) 23-28 July at Toronto Canada. |
| Year(s) Of Engagement Activity | 2016 |
| Description | A population perspective on dementia and its relationship with ageing and dying across time |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Invited speaker at Brocher foundation, Geneva, 14-15 April 2016. The redefinition of Alzheimer's disease and its social and ethical consequences. |
| Year(s) Of Engagement Activity | 2016 |
| Description | A presentation to the ARUK DEMON network applied models working group |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I presented a talk entitled "Identifying blood biomarkers associated with cognitive decline and structural brain changes in older age" to scientists who are members of the Applied Models and Digital Health working group of the DEMON network, which is an international network for applying data science and AI to dementia. |
| Year(s) Of Engagement Activity | 2021 |
| Description | A public health researcher's reflections on ethics informed consent our directin of travel and population studies of brain ageing |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | Up to date Alzheimer Disease researcher thinking from clinical and biomedical standpoints. |
| Year(s) Of Engagement Activity | 2015 |
| Description | A talk or presentation - Professor Thompson Robinson 'Rates, Risks and Routes to Reduce Vascular Dementia update' |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Thompson Robinson gave an update on 'Rates, Risks and Routes to Reduce Vascular Dementia' at the West Midlands LCRN Meeting on 27th September 2019 |
| Year(s) Of Engagement Activity | 2019 |
| Description | A talk or presentation - Professor Thompson Robinson 'Rates, Risks and Routes to Reduce Vascular Dementia update' |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Thompson Robinson gave a talk on 'Rates, Risks and Routes to Reduce Vascular Dementia' at the South West Peninsula and West England LCRN Meeting on 5th November 2019 |
| Year(s) Of Engagement Activity | 2019 |
| Description | A-Level workshop in the Oxford Natural History museum |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | A-Level workshop in the Oxford Natural History museum March 2017 Naiara Demnitz |
| Year(s) Of Engagement Activity | 2017 |
| Description | AAIC 2017 - Dementias Platform UK Showcase presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A talk from several DPUK work packages on the component products and research ongoing as part of the Data Portal setup |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://portal.dementiasplatform.uk |
| Description | AAIC 2017 DPUK quick-fire symposium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Theme: Public Health and Psychosocial Session Title: Focused Topic Session: The Dementias Platform UK Informatics Infrastructure: A Live-Fire Exercise Session Overview: The DPUK informatics infrastructure is the most comprehensive set of data access and management tools available to dementia research, covering cohort data, EHR linkage, imaging, wearables and genetics. It also provides access to a depth and breadth of data that cannot be found elsewhere. This feature research session will showcase the various components of the platform using live-online examples to demonstrate its ease and flexibility of use. Learning Objectives: • Describe the range of DPUK informatics tools available to the research community • Demonstrate the range of DPUK informatics tools available to the research community • Illustrate opportunities for international collaboration using DPUK informatics tools Slot: Wednesday, July 19, 2017: 2:00 PM-3:30 PM |
| Year(s) Of Engagement Activity | 2017 |
| Description | AAIC Los Angeles Annual Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | MODEL-AD presentation - Alzheimer's Susceptibility Genes Implicate Microglial Activity |
| Year(s) Of Engagement Activity | 2019 |
| Description | AARP press release on Global Council on Brain Health (GCBH) report "New Report Highlights Links Between Cardiovascular and Brain Health", highlighting the links between cardiovascular and brain health, 10th February 2020 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | AARP press release on Global Council on Brain Health (GCBH) report "New Report Highlights Links Between Cardiovascular and Brain Health", highlighting the links between cardiovascular and brain health, 10th February 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://press.aarp.org/2020-2-10-Report-Highlights-Links-Between-Cardiovascular-and-Brain-Health. |
| Description | ALZFORUM, article mentioning Insight 46 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A news article in ALZFORUM entitled, "Brain damage from cardiovascular disease starts earlier than you think". This article mentions data from Insight 46 and explanatory information provided by members of the Insight 46 data-collection team. |
| Year(s) Of Engagement Activity | 2018 |
| Description | ARUK 2014 Annual Meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | Yes |
| Type Of Presentation | keynote/invited speaker |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Julie Williams took part in a debate at the 2014 ARUK conference titled: Alzheimer's disease: The relative importance of Genes and Environment The conference audience took part in the debate and positive feedback was recieved about this part of the conference. |
| Year(s) Of Engagement Activity | 2014 |
| URL | http://www.alzheimersresearchuk.org/conference-programme/ |
| Description | ARUK Clinical Conference. talk titled "What's new in Frontotemporal Dementia?" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | This conference focussed on the themes of research, innovation, and implementing change in clinical practice. |
| Year(s) Of Engagement Activity | 2021 |
| Description | ARUK Conference 2020 press release |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | My research was featured in the conference press release, which was published on the ARUK website as well as range of outlets of the PA Media Group (which reached over 72 million - statistics provided by PA Media Group). My virtual poster presentation received some interest and there was some discussion on Twitter. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.alzheimersresearchuk.org/early-life-hardship-linked-to-decline-in-memory-and-thinking/ |
| Description | ARUK Network Open Morning |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | About 150-200 people attended a morning of talks from Oxford researchers, including presentations on using stem cells in dementia research. |
| Year(s) Of Engagement Activity | 2015,2016 |
| Description | ARUK Online Open Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Alzheimer's Research UK Thames Valley Network Dementia Open Day Information Event |
| Year(s) Of Engagement Activity | 2020 |
| Description | ARUK Oxford Drug Discovery Institute |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presenter at the ARUK Oxford Drug Discovery Institute (ODDI) Collaborators meeting |
| Year(s) Of Engagement Activity | 2020 |
| Description | ARUK Oxford network dementia information event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Open day of talks and information stands organised by Alzheimer's UK Oxford Research Network at John Radcliffe Hospital. Talk by Sana Suri on Brain-Heart links |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.oxdare.ox.ac.uk/public-events |
| Description | ARUK Public Engagement open day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Public engagement |
| Year(s) Of Engagement Activity | 2015 |
| Description | ARUK Roundtable |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | I have been invited and participated in a Roundtable discussion organized by Alzheimer's Research UK: "Where now for Alzheimer's disease research? Learning from recent clinical trials failures and planning for the future", 19 January, 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | ARUK Scientific meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Scientific meeting |
| Year(s) Of Engagement Activity | 2015 |
| Description | ARUK Technical Workshop |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Collaborative workshop to discuss the technical infrastructure of data sharing platforms, including DPUK to facilitate targeted treatments and research. Outcomes have resulted in collaborative networks, invitation to join steering committee, future workshop hosting (DPUK Data Portal), co-hosting of Datathons with ARUK-Turing, collaboration on a grant application and intellectual sharing of ideas. |
| Year(s) Of Engagement Activity | 2018 |
| Description | ARUK Thames Valley Network Dementia Research day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 1st July 2022, The ARUK Thames Valley network hosted a Dementia Research day. The host was Becky Carlyle, ARUK Thames Valley Network coordinator. The day include presentations by Becky Carlyle, Peter Kilfeather, Hugo Fernandes, and Maria Claudia Caiazza from the Wade-Martins lab. |
| Year(s) Of Engagement Activity | 2022 |
| Description | ARUK Thames Valley Network Translational Research in Dementia - Collaboration building event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On Friday 11th November 2022, the ARUK Thames Valley Network hosted a Translational Research in Dementia - Collaboration building event at Oxofrd Brookes University. The event was hosted by Becky Carlyle ARUK Thames Valley Network coordinator and Dr Patrick Esser, ARUK Thames Valley Network Committee member. It was attended by researchers from Oxford Brookes University, University of Oxford and the University of Reading. |
| Year(s) Of Engagement Activity | 2022 |
| Description | ARUK UCL network public engagement called "Meet the Scientist", 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Sarah James, Kirsty (Macpherson) Lu, Hannah Carr, and Maria Popham participated in an ARUK-UCL network public engagement event called "Meet the Scientist". The Insight 46 team members set up an information stall called "Insight 46: Scanning people in the longest-running British Birth Cohort". The stall included information about the MRC National Survey of Health and Development and about Insight 46, including examples of cognitive tests. |
| Year(s) Of Engagement Activity | 2018 |
| Description | ARUK YouTube Channel |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | You tube channel for Alzhiemer's Research UK Oxford network centre. Includes talks from open days, panel discussions and short Q&A videos. |
| Year(s) Of Engagement Activity | 2015,2017,2018 |
| URL | https://www.youtube.com/channel/UCU_wr013kmYXypvNCRzU3JA |
| Description | ARUK conference 2015 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Participants in your research and patient groups |
| Results and Impact | Lots of questions More interest in taking part in dementia research |
| Year(s) Of Engagement Activity | 2015 |
| Description | ARUK genetics filming for FAD |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | ARUK network 2019 Exeter |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | The event was organised between the ARUK Bristol & Bath, Southwest (Exeter and Plymouth) and Wales networks. The aim was for members to meet, showcase research & build collaborations. J Williams spoke on Research infrastructure and resources: UKDRI as member of Cardiff University and UK Brain Banks Network |
| Year(s) Of Engagement Activity | 2019 |
| Description | ARUK/BRC Oxford Dementia Research Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | a day of talks celebrating the exciting research in the region including updates on some of the exciting big dementia research initiatives such as the ARUK Oxford Drug Discovery Institute, Dementia Platform UK, the NIHR Oxford Health Biomedical Research Centre and the Oxford Momentum Award. Accredited for 5 CPD credits. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.dpag.ox.ac.uk/research/wade-martins-group/oxford-aruk-network-centre/research-day-2015 |
| Description | Academic Health Science Networks Webinar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Clare Mackay was invited to preset an AHSN Webinar in June 2017 |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://atlas.ahsnnetwork.com/ |
| Description | Administrative Data Research Network Conference - Belfast, June 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A presentation on the DPUK Data Portal and the potential applications of Administrative Data and Linked Health Data |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | Advisor on tv drama on the theme of dementia |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | TV Soap script editorial advisor on dementia theme |
| Year(s) Of Engagement Activity | 2021,2022 |
| Description | Advisory Group (PPI) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Advisory group set up for PPI for fellowship - based on the research carried out under the DPUK platform |
| Year(s) Of Engagement Activity | 2019 |
| Description | African Society Cambridge University Mentorship Programme - Dr Haddy Fye |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Served as a Mentor to African students applying for Postgraduate study at the University of Cambridge. Mentee has since gained acceptance for study within the Sciences. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Aligning Science Across Parkinson's (ASAP) Consortium Meeting on 1st and 2nd September 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 1st and 2nd September 2022, the first Aligning Science Across Parkinson's (ASAP) Consortium Meeting was held at the Department of Pharmacology, University of Oxford. The two day event included talks and posters from the Wade-Martins lab, the Cragg lab, the Magill lab, and from our collaborators Mark Howe (Boston) and Dinos Meletis (Karolinska). |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://twitter.com/ASAP_Research/status/1585270635118428163 |
| Description | Alzheimer Society - Interview Re Fellowship |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | Alzheimer's Association International Conference (AAIC) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Present research at AAIC, which is the largest international meeting dedicated to advancing dementia science. The purpose is to disseminate our research and to learn about current and novel research in dementia science. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Alzheimer's Association International Conference (AAIC) Chicago 2018 (Computer Adaptive Testing) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster: Computer Adaptive Testing to Improve Mental Health Testing for Dementia-Focused Epidemiological Research: Bauermeister, S. & Gallacher, J. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Alzheimer's Association International Conference (AAIC) Chicago 2018 (DPUK Poster) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster: Dementias Platform UK (DPUK) Data Portal - World-leading infrastructure facilitating and supporting innovative Dementias research: Orton, C. et al., (presented on behalf of) |
| Year(s) Of Engagement Activity | 2018 |
| Description | Alzheimer's Association International Conference (AAIC) Chicago 2018 (DPUK Talk) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation: Dementias Platform UK (DPUK) Data Portal: Bringing Researchers to Data & Using the Power of Cohorts. Talk given at the preconference for AAIC PIA DADA group. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Alzheimer's Association International Conference (AAIC) Chicago 2018 (Ontologies) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster: A New Generation Ontology for Cross-Cohort Dementia-Focused Epidemiological Research: Bauermeister, S. & Gallacher, J. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Alzheimer's Association International Conference (AAIC) London 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation: Item Response Theory (IRT) for improving efficiency and reliability of scale delivery, and analysis in epidemiological research: Bauermeister, S. & Gallacher, J. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Alzheimer's Research UK Conference - London - Poster Presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster on the Data Portal was presented and substantial interest developed over the day of its presentation. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | Alzheimer's Research UK Conference 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation: The MRC DPUK Data Portal: Bringing Researchers to Data: The Research Journey: Bauermeister, S, Gallacher, J. et al. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Alzheimer's Research UK Thames Valley Network dementia public evening event |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | On 12 October 2022, Becky Carlyle gave a public talk on behalf of the Alzheimer's Research UK Thames Valley Network at Keble College. The talk focussed on the accusations of scientific fraud in Alzheimer's Disease research that were reported in the press in July, and the implications of these accusations for patients, researchers, and the race to cure Alzheimer's Disease. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.eventbrite.co.uk/e/alzheimers-research-uk-thames-valley-network-dementia-public-evening-... |
| Description | Alzheimer's Society debate: How can we beat dementia in the next twenty years |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Organised by the Alzheimer's Society. this involved patients, carers, supporters and the media who have had subsequent interest in research. very positive feedback from the Alzheimer's Society who were grateful for the input. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Alzheimer's gene study achieves landmark breakthrough |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Cardiff University publicised publication in Nature Genetics "Genetic meta-analysis of diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing" - aiming to raise public awareness of research being undertaken at UK Dementia Research Institute Cardiff |
| Year(s) Of Engagement Activity | 2019 |
| Description | An invited interview at the Alzheimer's Research UK (ARUK) 2019 the Video Journal of Dementia |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | An interview for Video Journal of Dementia |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.vjdementia.com |
| Description | An invited interview on issues facing researchers in Brexit for the Cross Party Group on Medical Research for Alzheimer's Society, UK |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Have provided an opinion on issues facing researchers in Brexit for the Cross Party Group in the Welsh Assembly looking at Medical Research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Annual meeting of Organization for Human Brain Mapping (OHBM), Vancouver |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Vaanathi Sundaresan:Poster: "Modelling white matter hyperintensities distribution within a population using Bayesian Inference." Eniko Zsoldos: Poster: 'Mid-life composite measures of biological aging predict structural integrity measures in later life'. Johannes Klein Poster "Prefrontal network dysfunction in prodromal and manifest Parkinson's disease" |
| Year(s) Of Engagement Activity | 2017 |
| Description | Annual report 2017 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The annual report summarised key areas of progress in Dementias Platform UK in 2017. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.dementiasplatform.uk/about/annual-report-2017 |
| Description | Anti-Microbial Resistance Databank collaboration meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | An invite to present the DPUK Data Portal as an exemplar use case of the UK Secure eResearch Platform, to a group interested in using the infrastructure. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://portal.dementiasplatform.uk |
| Description | Article featured on the DPUK website (Can a type of supportive brain cell rescue neurons damaged by Parkinson's disease? - DPUK (dementiasplatform.uk)) |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | In October 2021, an article about Naroa Ibarra Aizpurua's research was featured on the DPUK website, titled, 'Can a type of supportive brain cell rescue neurons damaged by Parkinson's disease?' |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dementiasplatform.uk/research-hub/stem-cell-network/can-a-type-of-supportive-brain-cell-... |
| Description | Article in daily mail featuring DPUK study |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Principal Investigator of the Deep and Frequent Phenotyping (DFP) study was interviewed by the Daily Mail. The article stressed the importance of studies like DFP which will help researchers develop treatments at the early stages in the development of Alzheimer's disease. This raised the importance of this type of work amongst the general public. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.dailymail.co.uk/health/article-5437893/Could-anti-stress-drug-help-beat-Alzheimers |
| Description | Article in newspaper (The Times) - performance of eight-year-olds on a test of thinking skills may predict how they will perform on tests of thinking and memory skills when they are 70. |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Increased public interest and support in dementia research |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.thetimes.co.uk/article/children-who-do-puzzles-reduce-risk-of-dementia-in-later-life-z0z... |
| Description | Article in the Observer - Vaccination for AD |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | Artificial Intelligence for Precision Dementia Medicine Summit at the Royal Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited to the round table discussion at the Artificial Intelligence for Precision Dementia Medicine Summit at the Royal Society |
| Year(s) Of Engagement Activity | 2022 |
| Description | AstraZeneca drug libraries article on DPUK website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Article on Astra Zeneca Drug library screening on DPUK website accessible in the "For Researchers" tab then "Our Research Communities" Facilitated by DPUK, scientists at the University of Oxford are investigating the behaviour of drugs developed by AstraZeneca (AZ) on patient-specific cell models. They are looking to see if they can be used to target a range of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.dementiasplatform.uk/our-impact/repurposing-drug-libraries |
| Description | Attend Parkinson's UK engagement event at St James' Palace, London |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Attend reception at St James' Palace to raise awareness for Parkinson's disease |
| Year(s) Of Engagement Activity | 2018 |
| Description | Attended the ARUK Oxford Network Outreach Day in March 2019 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | The 2019 Dementia Awareness Day was held at the John Radcliffe Hospital in Oxford in March 2019. The Oxford ARUK Network Centre organise this event to discuss current dementia research taking place within the network centre, which includes the University of Oxford, Oxford Brookes University and University of Reading. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.oxdare.ox.ac.uk/openday2019 |
| Description | BBC Horizon - filming 2015-16 |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | BBC Horizon were interested in making a programme about Alzheimer's disease with a focus on novel technology - especially imaging - for early diagnosis and trials. Several meetings were held with the produced and his team and then several days of on-site filming including following a research subject. The film is due to be shown in Spring 2016 as a one hour long programme which is likely to reach an audience of more than a million |
| Year(s) Of Engagement Activity | 2015,2016 |
| Description | BBC One Saturday Breakfast News - Funny Side of Parkinson's |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Richard Wade-Martins appeared on BBC One Saturday Breakfast News with Paul Mayhew-Archer to discuss our research using stem cell technology to grow and study dopamine neurons from skin cells. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.bbc.co.uk/news/health-35734888 |
| Description | BBC Panorama |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Julie Williams Research Team were approached to be involved in a BBC documentary. The documentary followed one of our research participants and his family through everyday life with Alzheimer's disease. Field workers and laboratory staff were also filmed in their roles. The documentary was screened on BBC1 in Panorama on 2nd June 2016. |
| Year(s) Of Engagement Activity | 2016 |
| Description | BBC Radio Cornwall interview on British Heart Foundation vascular dementia campaign, 7th March 2020 |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | BBC Radio Cornwall interview on British Heart Foundation vascular dementia campaign, 7th March 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.bbc.co.uk/programmes/p083w1v9 |
| Description | BBC South News television interview for My Beautiful Brains project |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | An interview conducted for BBC news south, speaking about the My Beautiful Brains project working with the Black Dementia company to host awareness and art workshops for minorities with dementia. |
| Year(s) Of Engagement Activity | 2022 |
| Description | BBC Wales |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | I have given an interview for BBC Wales, broadcasted 20 April 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | BBC Wales Dementia Week 2016 |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Filming with BBC Wales's Owain Clarke on Thursday (12th May, 10-12). Interview is part of a package he's doing for Alzheimer's Awareness Week. Owain will be asking Prof Williams about Wales's research contribution; her own specific research and; look ahead at what's next. Various excerpts were screened on BBC news throughout the week, featuring a number of different staff from the team at Cardiff. This raised awareness of our work and the profile of the team. |
| Year(s) Of Engagement Activity | 2016 |
| Description | BBC panorama |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | BBC Panorama are following an EOAD participant. The initial interview was filmed by the BBC |
| Year(s) Of Engagement Activity | 2016 |
| Description | BBC radio 'World at One' mini-series |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | A two-part mini series on the Deep and Frequent Phenotyping study (one of the DPUK work packages) was broadcast on BBC radio 4's World at One programme and on the BBC world service. The series profiled the scientists' work, setting out the importance of participation in dementia research studies and the current focus on early stage trials for dementia. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://soundcloud.com/user-172249820/world-at-one-26-27-june-2017 |
| Description | Big Data - next big thing: evaluation. Presentation to 1st NHS Wales Digital Health and Care Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited talk on the future of health informatics and 'Big Data' for the NHS. The purpose was to demonstrate what was already happening, how evaluations of numerous interventions were being carried out using multi-sectoral data linkage, how this was also supporting DiscoverY Science and the potential for these activities to grow into normal practice for the NHS and wider public services. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Big data and public health |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sanda Macara BMA Memorial Lecture, Cardiff |
| Year(s) Of Engagement Activity | 2020 |
| Description | Biochemistry Society LRRK2 Meeting, Lille, France |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 30 June 2022, Professor Wade-Martins gave a talk titled, 'The role of LRRK2 in the autophagic/lysosomal pathway' at the Biochemistry Society LRRK2 Meeting, Lille, France |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.eventsforce.net/biochemsoc/frontend/reg/tAgendaWebsite.csp?pageID=44265&daySelector=3&ev... |
| Description | Biomarkers - the be all and end all of dementia diagnosis? AAIC, Chicago |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2018 |
| Description | Biomarkers: Mechanisms and Targets |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof. Rowe chaired an expert panel on Biomarkers at the the Dementias Platform UK Translations 2023. This included discussions wih world leaders in this field of research from Academia and Industry as well as presentations from Early Career Researchers. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.dementiasplatform.uk/research-hub/translation-2023 |
| Description | Blog Article "Finding cures for vascular dementia" on the British Heart Foundation website (13 March 2020) |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Blog Article "Finding cures for vascular dementia" on the British Heart Foundation website (13 March 2020), featuring The University of Edinburgh SVD Research led by Professor Joanna Wardlaw. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.bhf.org.uk/what-we-do/news-from-the-bhf/news-archive/2020/march/finding-cures-for-vascul... |
| Description | Blog by Bryan Ng on DPUK website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A Blog was written and posted on the DPUK website on 21 April 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dementiasplatform.uk/news-and-blogs/blog/pioneering-stem-cell-research-dementia |
| Description | Blog by Bryan Ng on DPUK website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Article on DPhil student Bryan Ng's project in Richard Wade-Martins' lab. Disease-in-a-dish studies open a window to a new level of detail in dementia |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/blog/disease-in-a-dish-studies-open-a-window-to-a-new-level-of-deta... |
| Description | Blog post for Oxford Health BRC |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Blog post entitled "Investigating Neuronal Oscillations in Ageing and Dementia", authored by Andrew Quinn, Jemma Pitt, Méadhbh Brosnan, Sarah Clayton, & Kia Nobre from the Brain & Cognition lab & OxDARE team for Dementia Action Week 2021. The blog was intended for the general public and included sections on what MEG is, what it's like to have a MEG scan, and what we know about MEG and Dementia.The blog was posted on the NIHR Oxford Biomedical Research Centre website. The |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://oxfordhealthbrc.nihr.ac.uk/investigating-neuronal-oscillations-in-ageing-and-dementia/ |
| Description | Blog post on Dementias Platform UK website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | The blog post described the project and main outcomes of the research conducted during a DPUK Discovery Award. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dementiasplatform.uk/news-and-media/blog/dpuk-discovery-award-winner-tackles-discrepanci... |
| Description | Booth at Alzheimer's Association International conference 2017 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Visitors to the DPUK booth at the AAIC conference were able to learn more about DPUK's free resources for researchers through DPUK staff and scientists, literature and practical demonstrations of the Data Portal. The principal impact was awareness raising of DPUK's resources and funding amongst key users (the researchers) and other funders in the dementia research sector. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.dementiasplatform.uk/upcoming-events/aaic-2017 |
| Description | Brain Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | The Guarantors of Brain was set up to promote teaching, education and research in neurology and related disciplines. In 2021, we put on our first conference - run as a 2-day online conference, with a focus on clinical neurology and research. The conference was attended by almost 2000 delegates across the globe. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Brain Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Invited speaker |
| Year(s) Of Engagement Activity | 2022 |
| Description | Brain Conference, talk given on "Apathy and Impulsivity" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation during cognition and dementia theme of Brain conference 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Brain Health/Biomarker Panelist at BIOMED Conference 2018, Tel Aviv |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | A key point for discussion in the overall Brain Health track was that there is abundant opportunity for us to discover new ways to treat brain disease, and in particular age-related dementias. Tapping into this potential, however, will require better ways of diagnosing, distinguishing, characterising and tracking dementias so that we can understand better which patients we are trying to treat, and how to target their particular set of biological and behavioural phenotypes. In this context, we will be asking the "Getting Closer to Validated Biomarkers" panel to explore where we are now, where we need to be, and how to get there. Each panellist spoke for 5-10 minutes on any aspect of this topic. John's fellow panelists were Prof Nir Giladi, a clinical and research specialist in Parkinson's and movement disorders (please see quick biography from the Michael J Fox Foundation website https://www.michaeljfox.org/foundation/researchers.php?id=924) and Mike Irizarry, a senior leader in Eli Lilly's neuroscience group with medical and academic experience in Alzheimer's and other dementias and in public health. This involvement developed relationships with key industry contacts in the UK dementia landscape (eg the DDF) and lead to several enquiries from industry colleagues about how they could collaborate with DPUK. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://kenes-exhibitions.com/biomed/ |
| Description | Brains for Dementia Research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A public engagement event for brain donors, their carriers and the researches who will access the data. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Brains for Dementia Research Study Day |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on the use of BDR data on the DPUK Data Portal to the cohort study panel |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | British NeuroPsychiatric Association Annual meeting 24th February - medalist Lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Discussion of nosological challanges in Dementia |
| Year(s) Of Engagement Activity | 2016,2017 |
| URL | http://bnpa.org.uk/wp-content/uploads/2017/02/BNPA-FINAL-PROGRAMME-2017.pdf |
| Description | British Heart Foundation Donations Appeal feature on vascular dementia, February 2020. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | British Heart Foundation Donations Appeal feature on vascular dementia, February 2020. |
| Year(s) Of Engagement Activity | 2020 |
| Description | British Neuropathological Society meeting, Cirencester, UK 3-5 July 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attended by Dr Luca Passamonti and Dr Sanne Kaalund to strenghten their network in neuropathology research. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.bns.org.uk/wp-content/uploads/2018/12/Programme_BNSSummerSchool2019.pdf |
| Description | British Neuroscience Association Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Sana Suri: Talk: British Neuroscience Association Conference, Birmingham April 2017: "The APOE Paradox" |
| Year(s) Of Engagement Activity | 2017 |
| Description | British Science Festival 2016 Workshops |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | We used VR tools to demonstrate the impact of dementia on people's everyday lives. These included using the experiences "A Walk Through Dementia", our citizen science game "Sea Hero Quest", some activities from out children's website, as well as hands on activities and memory games. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.britishsciencefestival.org/ |
| Description | Brookes University Ageing Well Event 11th November 2020 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Ageing well event |
| Year(s) Of Engagement Activity | 2020 |
| Description | Bryan Ng attended the Alzheimer's Association International Conference and presented a poster in July 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In July 2019, Bryan Ng attended the Alzheimer's Association International Conference and presented a poster. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://c-path.org/poster-presentation-at-the-2019-alzheimers-association-international-conference-j... |
| Description | Buchanan et al - Oral presentation at ABN 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Buchanan SM, Parker TD, Lane CA, Keshavan A, Keuss SE, Schrag AE, Fox NC, Richards M, Schott JM. Relationships between walking speed, cognition and brain pathologies: an imaging study of the 1946 birth cohort. Oral presentation at ABN 2019. Increased awareness in sector about importance and impact of work. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.theabn.org/ |
| Description | Buchanan et al - Oral presentation at ARUK Student Day 2019. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Undergraduate students |
| Results and Impact | Keshavan A, Lane CA, Parker TD, Lu K, Cash DM, Sudre CH, Nicholas JM, Heslegrave AJ, James S-N, Murray-Smith H, Buchanan SE, Thomas D, Malone IB, Wong A, Richards M, Zetterberg H, Fox NC, Schott JM. Blood biomarkers of amyloid, tau and neurofilment light chain in the 1946 British birth cohort - relationships with cerebral amyloid and brain imaging. Oral presentation at ARUK Student Day 2019. Increased awareness of importance and impact of work amongst colleagues. |
| Year(s) Of Engagement Activity | 2019 |
| Description | CFAS DPUK Site Visit - November 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being CFAS. This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. Post-event, a meeting with CFAS' other key investigator, Prof Fiona Matthews in Newcastle University, was arranged to continue discussions further. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.cfas.ac.uk/ |
| Description | CPATH 2020 Annual Meeting and Regulatory Science Workshop - Virtual |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The Critical Path for Alzheimer's Disease (CPAD) is a Critical Path Institute public-private partnership aimed at generating actionable solutions and knowledge towards advancing drug development across the AD continuum. The key objectives of the meeting are: ?Scientific dialogue to guide the strategic development of comprehensive disease progression models spanning the AD continuum by utilizing advanced quantitative modeling methodology, such as nonlinear mixed effects approaches, artificial intelligence, and machine learning. ?Achieve consensus on gaining actionable information from fluid and imaging biomarker data for use in quantitative analysis and disease progression modeling, for the purpose of developing regulatory-endorsed model-informed quantitative Drug Development Tools in Alzheimer's Disease. 9:30 - 9:35 a.m. Welcome Remarks - Klaus Romero (Chief Science Officer, C-Path) 9:35 - 9:50 a.m. Welcome and Consortium Overview - Sudhir Sivakumaran (Executive Director, CPAD, C-Path) 9:50 - 10:10 a.m. CPAD Industry Co-Director Remarks - Nusrat Rabbee (NBG Head of Statistical Methodologies & Data Science, Eisai Co., Ltd.) 10:10 - 10:15 a.m. Data Sharing Pioneer Award 10:15 - 10:35 a.m. Keynote 1: Model-Informed Drug Development (MIDD) in Alzheimer's disease: From Data Sharing to Actionable Solutions - Jackson Burton (Executive Director, Quantitative Medicine, C-Path) 10:35 - 10:50 a.m. Keynote 2: Integration of Biomarkers and Quantitative Modeling - CSF - Kaj Blennow (Professor, University of Gothenburg) 10:50 - 11:05 a.m. Keynote 3: Integration of Biomarkers and Quantitative Modeling - Plasma - Henrik Zetterberg (Professor, University of Gothenburg & University College London) 11:05 - 11:20 a.m. Keynote 4: Integration of Biomarkers and Quantitative Modeling - Imaging - Brian Gordon (Asst. Professor, Washington University School of Medicine in St. Louis) 11:20 - 11:35 a.m. Keynote 5: Integration of Biomarkers and Quantitative Modeling - Analytical Validation and Standardization of Fluid Biomarkers - Charlotte Teunissen (Professor, VU University Medical Center) 11:35 - 11:45 a.m. BREAK 11:45 a.m. - 12:55 p.m. Expert Panel: Challenges and Opportunities for the Integration of Biomarkers and Models (Moderators - Jackson Burton and Sudhir Sivakumaran) - Billy Dunn (Director (Acting), Office of Neuroscience (ON), CDER, FDA) - Kevin Krudys (Senior Clinical Analyst for Quantitative Analysis and Modeling, ON, CDER, FDA) - Eric Bastings (Acting Deputy Director (ON) and Director (DNI), CDER, FDA) - Nusrat Rabbee (NBG Head of Statistical Methodologies, Eisai Co., Ltd.) - Adam Schwarz (Senior Director, Takeda Pharmaceutical Company Ltd) - Duygu-Tosun Turgut (Assoc. Professor, University of California, San Francisco) - Oskar Hansson (PI, BioFINDER; Professor, Lund University; Consultant Neurologist, Skåne University Hospital) - Keynote Speakers 12:55 - 1:00 p.m. Closing Remarks - Sudhir Sivakumaran (Executive Director, CPAD, C-Path) |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://c-path.org/critical-path-for-alzheimers-disease-2020-annual-meeting-and-regulatory-science-w... |
| Description | CSaP talk - How to stop bad data driving out the good in an age of misuse, misleadingness and misinformation |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | CSaP talk - How to stop bad data driving out the good in an age of misuse, misleadingness and misinformation 4 March 2019 Ed Humpherson is the CEO of the Office of Statistics Regulation. He gave an elegant talk about how numbers can be used poorly - The Number, misleading and too much unsignposted data. He talked about creating standards and reporting on these, how his office has interacted with government departments to call such practice out and how they have responded. He also talked about responsible media. I gained insight into how such a government function can operate to hold government to account. It highlighted the fact that this is possible to do within a (relatively) stable governmental/public domain structure but that it would be unlikely professional integrity heading for CPD. |
| Year(s) Of Engagement Activity | 2019 |
| Description | CURE ND Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Workshop to discuss disease models in the field of neurodegeneration, what are the most advanced models to date, how accurate are they, and what is missing in terms of modelling |
| Year(s) Of Engagement Activity | 2021 |
| Description | Cambridge Imaging Festival - Talk: New directions in dementia imaging |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | This is a meeting of users and experts within the Cambridge NHS and academic community. Results and data are shared as well as new perspectives and applications for novel imaging methods. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.mrc-cbu.cam.ac.uk/wp-content/uploads/2021/05/Programme-Cambridge-Imaging-Festival-2021.p... |
| Description | Caution when looking at cell recycling in Parkinson's |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | Media press release by Parkinson's UK highlighting that researchers at the Oxford Parkinson's Disease Centre have shown that cell recycling in Parkinson's may play a more complex role than previously thought. These new results have been published in the journal of Cell Reports. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.parkinsons.org.uk/news/caution-when-looking-cell-recycling-parkinsons |
| Description | Cecilia (Heyne) Lee Pint of Science Public Engagement Talk, Oxford |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Pint of Science Public Engagement Talk, Oxford, Autumn 2016 on using iPSC for modelling neurodegeneration |
| Year(s) Of Engagement Activity | 2016 |
| Description | Celebrating international day of women and girls in science. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In February 2022, we celebrated international day of women and girls in science by sharing a video featuring three of our researchers Becky Carlyle, Charmaine Lang, and Gabriela Vilema Enriquez |
| Year(s) Of Engagement Activity | 2022 |
| URL | http://youtu.be/U0yGdxZ7k2A |
| Description | Chair of session "Brain, Inflammation, Depression and Dementia" @ Cambridge Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Chair of of event on Brain, Inflammation, Depression and Dementia at annual Cambridge Festival. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://ftd.neurology.cam.ac.uk/events |
| Description | Cheltenham Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Hands-on experiments, the MakerShack, our brand new Cyber Zone, heartbeat art there was much to explore on site in 2018! From stargazing, fun activity trails, family days and heated discussions in the Conversation Corner to a large animal dissection live on the Festival site, Cheltenham Science Festival offers science galore for all ages. Dr Tara Caffrey took part in the day to talk about her research into Tau. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.cheltenhamfestivals.com/science |
| Description | Cheltenham Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The Festival theme 2019 was health and wellbeing, considering everything from the food we eat and our exercise regimes to cutting-edge medical research. As part of this theme, the event explored the latest breakthroughs in dementia research. The panel was asked to talk about the broad landscape in this field and its evolution in recent years, key achievements and challenges and an insight into how the diagnosis and treatment of dementia has changed and developed. J Williams talked about cutting-edge research and expertise and the exciting aspects of her own work within this area As populations have aged, dementia has become the fifth biggest cause of death worldwide. Yet despite its devastating consequences there is currently no cure. What do we know about this group of diseases, and are there things we can do to help reduce our risks and keep our brains fighting fit? Alzheimer's disease specialist Julie Williams and psychiatrist Ivan Koychev discuss the latest breakthroughs and discoveries that are helping to prevent, diagnose and treat dementia more effectively. |
| Year(s) Of Engagement Activity | 2011,2019 |
| Description | Cheltenham Science Festival |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | Yes |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Talk led to a lot of questions and discussion - for almost an hour after the event A number of people expressed interest in taking part in research |
| Year(s) Of Engagement Activity | 2014,2015 |
| URL | http://www.dementiasplatform.uk/event/cheltenham-science-festival/ |
| Description | Clare Mackay talk - New developments in Parkinson's and Alzheimer's research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | OPDC's Imaging lead Professor Clare Mackay and Masud Husain, Professor of Neurology and Cognitive Neuroscience, spoke at a talk open to all about "New developments in Parkinson's and Alzheimer's research". In this accessible and informative public talk they explored the latest research into the debilitating neurodegenerative disorders Alzheimer's and Parkinson's. They showed how cutting edge research is: increasing our knowledge of the mechanisms causing these disorders, offering the prospect of earlier diagnosis and supporting the development of potential new therapies to slow the progression of the disease. The talk was filmed as is available to view online |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://youtu.be/WtmCPdTdmPc |
| Description | Co-chair for a session at an ARUK workshop: tackling gaps in Developing Life-Changing Treatments for Dementia |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | A workshop on 15-16 May in London to critically evaluate the current gaps in progressing toward an effective therapeutic intervention, and develop tangible plans to resolve these gaps. We know that since the G8 summit in 2013, several initiatives and roadmaps have been developed to increase investment and global attention. However, reviews of progress and changes in the research landscape show key gaps that are not currently being addressed. John co-chaired a session (alongside Nick Fox) called - How do we choose the right patients for proof-of-concept clinical trials? This workshop strengthened relationships with key people involved in the dementia research landscape and influenced the design of the Great Minds clinical studies register in DPUK. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.alzheimersresearchuk.org/ |
| Description | Cognitive measures in DPUK cohorts: A resource for researchers. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | Calvin C, et al. (2018). Cognitive measures in DPUK cohorts: A resource for researchers. Poster presentation at Dementias Platform UK Annual Conference, British Medical Association, London on 23 April 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cognitive test harmonisation across Dementias Platform UK cohorts. |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Calvin C (2019). Cognitive test harmonization across Dementias Platform UK cohorts. Oral presentation at International Data Harmonisation ESRC Workshop on Cognitive Ageing and Dementia: Perspectives from the UK and Japan, University College London, 8th November 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Collaboration with science communicator/illustrator Nina Chhita |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Was interviewed by science communicator/illustrator Nina Chhita, whose work features women in science, and she did a series on DPUK female scientists. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.instagram.com/p/B6N8SyhpR-f/ |
| Description | Collaborative visit to Oxford by University of Sheffield on Tuesday 27 September |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Researchers from the University of Sheffield visited Oxford in September to discuss new data from our Michael J Fox funded Parkinson's project |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://twitter.com/HeatherMortiboy/status/1575834919724789763 |
| Description | Comment on the Polygenic Hazard scores for AD study by Tan et al (2019), Brain 142; 460-470 for Alzforum |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | I have commented on a study which was covered on Alzforum about polygenic hazard scores for AD, and shared my opinion on their availability to the public. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.alzforum.org/news/research-news/multi-gene-score-predicts-cognitive-decline-independentl... |
| Description | Company Visit (Boston) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | ~50 industrial partners attended my talk about blood biomarkers in neurodegeneration |
| Year(s) Of Engagement Activity | 2022 |
| Description | Conducting research through globally accessible trusted research environments, University of Sydney |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Conducting research through globally accessible trusted research environments, University of Sydney, 11/11/22 |
| Year(s) Of Engagement Activity | 2022 |
| Description | Contemporary populations and dementia, what have we learnt and where are we headed |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | A talk was given at Fourth Annual NHMRC National Institute for Dementia Research Australian Disease Forum 2019 at Hobart, Tasmania Keynote Address: Contemporary populations and dementia, what have we learnt and where are we headed? |
| Year(s) Of Engagement Activity | 2019 |
| Description | Contributed to Guardian Article with Hannah Devlin - Science Correspondent |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | UK falls from fourth to 10th place in phase III trials amid 'ossified' bureaucracy and stretched health service. Prof Rowe contributed to media article. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.theguardian.com/science/2023/feb/27/patients-losing-out-amid-slump-in-nhs-clinical-trial... |
| Description | Contribution to Medium article for Brain Awareness Week |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Article about our work with DPUK on the University of Oxford's Medium account |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://medium.com/oxford-university/brain-awareness-week-the-future-of-dementia-research-6f03f61cad... |
| Description | Contribution to the Oxplore website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | Contributed a section under the topic "4 ways researchers are working to fight dementia" on the Oxplore website (a digital outreach portal of the University of Oxford that tries to engage 11- to 18-year-olds from underrepresented groups). |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.oxplore.org/additional-resource/2502/2519 |
| Description | Contributor to UKRI Infrastructure Roadmap Cohort workshop |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | UK Research and Innovation (UKRI) has been requested by BEIS to develop a Research and Innovation Infrastructure Roadmap. The purpose of this is to highlight the current capabilities across the UK and to set out future infrastructure priorities. While the Roadmap is not linked to a capital budget, the priority areas are likely to influence capital spending priorities for UK government as it moves towards the ambition of providing 2.4% of UK GDP for research and development by 2027 . One of the infrastructure themes being developed is around population data for research. MRC is looking to hold a workshop to consult with leading experts to shape the development of two potential new cohorts this area: 1.Child to Early Adulthood Cohort 2.Early Diagnosis Cohort (from late 30s/early 40s). Participants would be asked to bring their knowledge and experiences to actively support MRC in developing the outline cohorts described above: • We would tap into your expertise to explore issues such as: o Purpose o Feasibility o Setting(s) o Sampling framework o Design o Biomedical, biosocial, environmental measures o Governance and access o Ethics & consent In addition, to the refinement of the options, we will be seeking views on how such investments would contribute to the national and international landscape. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Creating a national approach: the SAIL Databank |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Joint UK-Switzerland Research Symposium, Zurich |
| Year(s) Of Engagement Activity | 2019 |
| Description | Creation of OPDC news mailing list |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | There is now an option on the OPDC website to sign up to an OPDC news mailing list. This is used to send out news of outreach events and updates on our publications. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.opdc.ox.ac.uk/news-mailing-list |
| Description | Creation of wademartinslab_oxford instgram account |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Account for Wade-Martins lab for Molecular Neurodegeneration, University of Oxford to share news |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.instagram.com/wademartinslab_oxford/ |
| Description | DFP articles |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | https://www.neurodegenerationresearch.eu/fr/2016/08/uk-launches-major-study-to-detect-early-signs-of-alzheimers/ |
| Year(s) Of Engagement Activity | 2020 |
| Description | DFP website with updates |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | https://www.dementiasplatform.uk/our-impact/case-studies/deep-and-frequent-phenotyping-study |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dementiasplatform.uk/our-impact/case-studies/deep-and-frequent-phenotyping-study |
| Description | DPUK 5 Year celebratory event press pack |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | To develop greater media engagement with DPUK and DFP the DPUK 5 year celebratory event and press pack outlined the achievements of DPUK and DFP and provided media with interviewees including Vanessa Raymont of DFP and John Gallacher of DPUK and Hilary Doxford a research advocate with a dementia diagnosis. Media attending included the Evening Standard, Daily Mail, The Sunday Times, Daily Express, BBC Fergus Walsh, The Times and The Daily Telegraph. Those requesting the press pack: BMJ, The Times, Freelancers, The Guardian, Research Fortnight, Labmate, The outcome was a Today Programme interview with John, Daily Express interview with Hilary and follow engagement with Vanessa and John with the Sunday Times. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/news/bringing-dementia-research-together-dpuk-5-year-celebration-ev... |
| Description | DPUK 5 year celebratory event |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Prof John Gallacher hosted an expert panel to outline the achievements of five years for DPUK to an audience of media, peers, and policymakers. The panel included leads of the imaging (Prof Franklin Airghirio) and stem cell networks (Prof Rick Livesey), experimental medicine portfolio (Prof Paul Matthews) and Deep and Frequent Phenotyping study (Dr Vanessa Raymont) and Hilary Doxford - a member of the Three Nations Dementia Working Group. This resulted in: An interview with John Gallacher on Radio 4 Today programme. An interview with Hilary Doxford in the Daily express featuring the DFP study and research volunteers A follow up interview with John Gallacher in the Sunday Times about lifestyle, alcohol and dementia Website page visits for the event 541 Video plays: 1,568 Impressions: 47,564 Engagements: 1,229 |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/news/bringing-dementia-research-together-dpuk-5-year-celebration-ev... |
| Description | DPUK 5 year event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk and media coverage of the Deep and Frequent Phenotyping Study |
| Year(s) Of Engagement Activity | 2019 |
| Description | DPUK ALSPAC site visit |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sarah Bauermeister met with representatives of Bristol-based cohort, ALSPAC, to discuss hosting of their data on the DPUK Data Portal. The meeting was very fruitful, with the meeting over-running to due to ALSPAC's interest and questions on the systems. Following this engagement meeting, ALSPAC have been a supportive partner of DPUK, with John being asked to take part as an expert in meetings in ALSPAC-related projects, interviews promoted the ALSPAC-DPUK collaboration, and letters of support for further funding and collaboration in the future. |
| Year(s) Of Engagement Activity | 2019 |
| Description | DPUK Airwave cohort site visit - Jan 2020 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being Airwave. This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. Post-event, the Senior Manager for the Airwave cohort introduced John to key figure to help with Great Minds and data access work - Tom Denwood, Executive Director of Data, Insights and Statistics at NHS Digital. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.police-health.org.uk/ |
| Description | DPUK Annual Conference - Data Portal presentation session |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on the DPUK Data Portal at the DPUK Annual Conference |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | DPUK Annual Conference 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation: Neuroticism and cognitive change: Longitudinal evidence from 14 013 UK Biobank participants: Bauermeister, S. & Gallacher, J. |
| Year(s) Of Engagement Activity | 2017 |
| Description | DPUK Annual Conference 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation: The effect of childhood adversity on adult behavioural, psychological, cognitive and health outcomes: A UK Biobank & DPUK cross-cohort investigation: Bauermeister, S. & Gallacher, J. |
| Year(s) Of Engagement Activity | 2018 |
| Description | DPUK Annual Conference 2018: The power of cohorts 23 April 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The Dementias Platform UK (DPUK) conference - a day-long event on 23 April this year in London - is focused on supporting use of the Data Portal, and demonstrating the wider work that will draw on its resource. Researchers will be offered the chance to join practical workshops, learning alongside colleagues from a variety of sectors and contexts about what the Data Portal and other DPUK resources means for university researchers, and those working in industry in drug development. We are delighted to announce that the speakers at our annual conference 2018 are Professor Hugh Perry and Professor Miia Kivipelto. By supporting as many researchers as possible to use the Data Portal, through both funding and ongoing training, DPUK hopes to increase the chances of generating new insights and accelerating our progress towards new treatments for dementia. Sign up for your free place at the conference. For more information please visit www.dementiasplatform.uk/forresearchers Dementias Platform UK is a public-private partnership funded by the Medical Research Council. DPUK's partners - ten universities and six pharmaceutical companies - have joined forces with the aim of accelerating research towards effective treatment for dementia by improving access to data. By bringing together records from over 40 different cohort studies - including brain scans, genetics and clinical records - DPUK is creating the world's richest source of people data for use in research and drug development for dementia. This free-to-access resource of cohort data is available for use by any bona fide researcher who is interested in investigating dementia, whether based within a university or industry context. DPUK facilitates safe and secure access to this data through its Data Portal, enabling research and analyses at a scale that has not previously been possible for studies into dementia. DPUK wishes to promote scientific research using cohort study data. It has an active programme of experimental medicine and funds research using cohort data. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/conference-2018/programme-for-the-day |
| Description | DPUK Annual Review |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The Annual Review is a comprehensive 68-page publication featuring impact across DPUK's workstreams in 2018. It is available online and printed copies were sent to 200 people in industry, key funder organisations in the sector, collaborators, and research organisations in the dementia research landscape. The Annual Review has received very positive feedback from industry, in addition to a key funder organisation. |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018 |
| URL | https://www.dementiasplatform.uk/about/our-organisation#annual-review-2018 |
| Description | DPUK Article |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | https://www.dementiasplatform.uk/news-and-blogs/news/mrc-confirms-multi-million-pound-renewal-of-funding-for-dpuks-dementia-research |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dementiasplatform.uk/news-and-blogs/news/mrc-confirms-multi-million-pound-renewal-of-fun... |
| Description | DPUK Autumn Academy |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | DPUK Autumn Academy, following much the same format as a datathon, except with more of a teaching/seminar aspect. 30 early career researchers attended seminars on machine learning, data processing and advanced analysis techniques, utilising the DPUK dataportal and population cohort data. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dementiasplatform.uk/research-hub/data-analyst-training/dpuk-autumn-academy |
| Description | DPUK CHARIOT-Pro Site Visit - August 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being CHARIOT-Pro. This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. Sarah was able to follow up on CHARIOT's plans to upload baseline data and wondered how DPUK could facilitate this for them. This would be of benefit to both CHARIOT but also DPUK, to move cohorts moving from 'metadata only' to data upload as soon as possible, as well as provide an update on the anticipated Data Portal paper. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.imperial.ac.uk/school-public-health/ageing/research/ |
| Description | DPUK CamCAN Site Visit - November 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being CamCAN. This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. Post-event, John and Rik (CamCAN PI) have been in conversation with enhancing the cohort through imaging work. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.cam-can.org/ |
| Description | DPUK Cohort Collaboration Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK commissioned a cohort collaboration meeting to allow its network to facilitate cohort to cohort projects and to gain feedback on how DPUK can best support the science being already performed by cohorts and how to integrate this into the Data Portal. |
| Year(s) Of Engagement Activity | 2016 |
| Description | DPUK Cohort Seminar |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A cohort working group convened by DPUK to gather cohort staff, including principal investigator's, data managers and researchers, to disseminate information about DPUK's various work packages. Main involvement surrounded the ongoing build and operation of the DPUK Data Portal and Informatics Network. |
| Year(s) Of Engagement Activity | 2016 |
| Description | DPUK Cohort Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A meeting to discuss plans, Portal and general DPUK next steps, and gain advice from an expert panel of DPUK cohorts |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | DPUK Data Portal Live Demonstration |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A live demonstration of the operational DPUK Data Portal was given by Chris Orton, Data Project Manager for DPUK at Swansea University, at the DPUK Annual Scientific Meeting at the Royal College of Obstetricians and Gynaecologists, on 4th May 2017. The demonstration showed a live log-in of the system, including the security measures and services available to researchers. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://portal.dementiasplatform.uk |
| Description | DPUK Data Portal Workshop Presentation at the Analyst Seminar |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation of the DPUK Data portal: An overview its usability, tools, cohorts and application process for analysts and researchers. |
| Year(s) Of Engagement Activity | 2018 |
| Description | DPUK Data Portal Workshop Presentation at the DPUK Annual Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | An overview of the functionality of the DPUK Data Portal, how to Identify, Access and Analyse data on the Data Portal. The Outcome was an additional half hour of questions which resulted in a revised Q and A section on our DPUK website and also an increase in emailed enquiries about applying for cohort data. |
| Year(s) Of Engagement Activity | 2018 |
| Description | DPUK Data Portal demonstration at the EMIF/DPUK Joint Conference, February 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The DPUK Data Portal was demonstrated to researchers and policy makers from both DPUK and EMIF at the EMIF/DPUK Joint Conference in Manchester on 23rd February 2017. The session was designed to give a live run-through of the Portal, its tools, and its analytic potential, which inspired questions and interaction from the research community present. |
| Year(s) Of Engagement Activity | 2017 |
| Description | DPUK Data Portal presentation at UK DRI Big Data Workshop, London - 12/3/20 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Informative presentation for the purposes of ongoing collaborative interests. |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK Data Portal project: Early adversity and later life dementia oral presentation at the Alzheimer's European Conference 2020 - 19/10/20 to 23/10/20 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on early adversity research program conducted on the DPUK data portal. |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK Datathon alert |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The DPUK datathon alert communicates updates on confirmed hackathon-style multidisciplinary workshops dates, topics and bursaries. Of the four datathons to date 89 researchers have signed up to the alert and 92 ECRs, senior researchers and PIs attended |
| Year(s) Of Engagement Activity | 2019,2020 |
| Description | DPUK ELSA cohort site visit - Jan 2020 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being ELSA. This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. Post-event, ELSA was very enthusiastic about helping DPUK with its mission and continuing the strong partnership with the platform. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.elsa-project.ac.uk/ |
| Description | DPUK Epic Norfolk Site Visit - November 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being EPIC Norfolk This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. Post-event, the EPIC Norfolk team wanted to thank Sarah and John personally via e-mail for showcasing the DPUK website and portal development, and mentioned how all were impressed with the development of the new tool, and how the presentation gave them a greater understanding of the work that happens at DPUK. The attendees asked for Sarah's slide in order to share at the EPIC-Norfolk Management Committee. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.srl.cam.ac.uk/epic/ |
| Description | DPUK Exeter Datathon |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK Exeter Datathon held at the University of Exeter. 22 researchers convened to focus on machine learning and AI from two cohort datasets (ELSA, NACC), and used the DPUK Data Portal datathon virtual desktop to investigate this data and test methodology. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.exeter.ac.uk/news/events/details/index.php?event=9294 |
| Description | DPUK Exeter Datathon - Technical and research support |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Providing technical and research support for attendees at the DPUK Datathon held at Exeter university. Including cohort dataset knowledge, machine learning supprt and support on variaous other technical issues. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.exeter.ac.uk/news/events/details/index.php?event=9294 |
| Description | DPUK Generation Scotland Site Visit - September 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being Generation Scotland. This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. As a consequence, GenScot supported the Datathon initiative with Generation Scotland data and Archie Campbell gave a presentation on one day. The Swansea Datathon went well and one group were particularly interested in looking at polypharmacy across the cohorts used (BRACE; ELSA; Gen Scot; CaPS). Sarah will be following up with the groups again shortly to see how these ideas develop. Generation Scotland also agreed to become DPUK's first feature cohort - the basic idea being is that DPUK would have a feature on the website about the cohort and PI/Data manager and all the other great features of the Generation Scotland cohort. A member of the communications team conducted an interview in 2020 and took a few photos and a video. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.ed.ac.uk/generation-scotland |
| Description | DPUK Great Minds Event 20th Nov 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | Virtual event for participants |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK Great Minds Event 28th May 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | Virtual event |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK Infrastructure Presentation at the EMIF DPUK Joint Conference, February 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Simon Thompson, Head of IT for Swansea University Medical School, gave a talk on DPUK infrastructure at the EMIF/DPUK Joint Conference in Manchester on 23rd February 2017. The presentation outlined the completion of the infrastructure build and move to live operation of the DPUK Data Portal which had begun to provision data. |
| Year(s) Of Engagement Activity | 2017 |
| Description | DPUK Interview as senior data manager by University of Oxford. - 24/6/20 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | An interview conducted by Oxford University detailing personal academic career and working for DPUK as a senior Data Manager during a pandemic. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://staff.web.ox.ac.uk/article/a-day-in-the-life-with-dr-sarah-bauermeister |
| Description | DPUK LinkedIn channel |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The DPUK LinkedIn channel has grown to have 99 followers in February 2021. Efforts to grow the channel further will continue in the coming year. |
| Year(s) Of Engagement Activity | 2020,2021 |
| URL | https://www.linkedin.com/company/dpuk |
| Description | DPUK MRI-PET Imaging Network Launch |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK MRI-PET Imaging Network Launch - bringing awareness to the expertise and benefits of the DPUK colleagues in the Imaging Network, as well as the resource of the 7 scanners. Opening speech by former Chief Executive of the MRC. Engagement with current industry partners, enquiries from new industry colleagues. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/upcoming-events/dpuk-imaging-network-launch |
| Description | DPUK Monthly Bulletin |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The DPUK Monthly Bulletin communicates updates on resources, cohort data, changes in policy and guidelines, publications and funding opportunities to DPUK workstream members and internal audiences. The Bulletin has a 30% open rate (not-for-profits average 20%). |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018,2019,2020 |
| Description | DPUK NSHD/SABRE cohort site meeting - January 2020 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being NSHD/SABRE. This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. Post-event, NSHD has a better understanding and awareness of the benefits that DPUK and its Data Portal could bring to the cohort and analysis of its data. |
| Year(s) Of Engagement Activity | 2020 |
| URL | http://nshd.mrc.ac.uk/ |
| Description | DPUK New Generation Ontology Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A workshop for discussing the ontologies and sharing knowledge and good practice for a future DPUK cross-cohort epidemiological focused ontology. |
| Year(s) Of Engagement Activity | 2018 |
| Description | DPUK Newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The DPUK newsletter communicates resources, data updates and funding opportunities for researchers and funders of dementia research. It has a 31% open rate and 8% open rate |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018,2019 |
| Description | DPUK Next generation seminar: analytics |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | This DPUK workshop was designed to raise awareness of the Data Portal and key DPUK cohorts amongst data scientists. The workshop fostered collaborative working and the development of new proposals for analysis in the Data Portal. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/for-researchers/expert-communities-1/statisticians/next-generation-... |
| Description | DPUK November Virtual Datathon 2020 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | November Virtual datathon held over 2 weeks |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK Presentation at the Internation Population Data Linkage Network Conference, Swansea, August 2016 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A presentation was given on DPUK infrastructure and informatics work at the IPDLN Conference, hosted at Swansea University in August 2016. The presentation was in front of an audience of international researchers and policy makers and explained the UKSeRP architecture used by DPUK and the plans to integrate cohort data and enhance modality knowledge. |
| Year(s) Of Engagement Activity | 2016 |
| Description | DPUK Presentation: IHCC summit meeting on global impact of Covid-19 on mental health. - 9/11/20 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A prestation on IHCC funded projected conducted on the DPUK Dataportal investigating global impact on COVID-19 on mental health. |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK Reach |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Launch of reach- online forum for researchers |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://reach.dementiasplatform.uk/index.php?p=/ |
| Description | DPUK Remote Cognitive Testing Event 9th October 2020 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cognitive testing event- virtual |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK Stakeholders Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Raised awareness of use of stem cells in dementia research |
| Year(s) Of Engagement Activity | 2015 |
| Description | DPUK Swansea Datathon |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK Swansea Datathon held at Swansea University - October 2019. 25 researchers convened to investigate the co-morbidity of dementia across 4 DPUK cohorts' data - BRACE, CaPS, ELSA, Generation Scotland. The event consisted of talks on each of the cohorts and analysis sessions to explore and investigate data across teams. Findings were reported in a final presentation session on the third day. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://popdatasci.swan.ac.uk/population-data-science-at-swansea-university-dpuk-datathon/ |
| Description | DPUK Swansea Datathon - Technical and research support |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Providing technical and research support for the DPUK Datathon held at Swansea university. Including cohort dataset knowledge, machine learning supprt and support on variaous other technical issues. |
| Year(s) Of Engagement Activity | 2019,2020 |
| URL | https://popdatasci.swan.ac.uk/population-data-science-at-swansea-university-dpuk-datathon/ |
| Description | DPUK Turing Institute Datathon |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A DPUK Datathon held at the Alan Turing Institute in London. The event comprised 42 researchers using the DPUK Data Portal datathon virtual desktop to investigate data from the Deep and Frequent Phenotyping study. The focus of the Datathon was on machine learning and artificial intelligence, and made use of phenotypic and imaging data from the DFP pilot. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.turing.ac.uk/events/innovative-data-science-alzheimers-research |
| Description | DPUK Twitter channel (@DementiasUK) |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | DPUK Twitter follower count stands at 4,388 in February 2021 - 964 new followers (approx 28% increase) across previous 12 months. |
| Year(s) Of Engagement Activity | 2020,2021 |
| URL | https://twitter.com/DementiasUK |
| Description | DPUK UEA Datathon |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK Datathon held at University of East Anglia. 60 researchers convened to explore and investigate data from 3 DPUK cohorts (ELSA, CaPS, DFP), using the DPUK Data Portal datathon virtual desktop. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/upcoming-events/dpuk-datathon-2013-uea |
| Description | DPUK UEA Datathon - Attendee / Technical and research support |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Taking part in the DPUK UEA Datathon and being involved both as an attendee and as a DPUK representative, providing technical and research support. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.uea.ac.uk/medicine/engagement/blog/-/blogs/datathon-success |
| Description | DPUK UEA Datathon - Technical and research support |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Providing technical and research support for attendees of the DPUK Datathon held at the University of East Anglia. Including cohort dataset knowledge, machine learning supprt and support on variaous other technical issues. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.uea.ac.uk/medicine/engagement/blog/-/blogs/datathon-success |
| Description | DPUK Virtual Datathon June 2020 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | First virtual Datahon over two weeks in June 2020 |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK Website feature iPSCs: a shared resource |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Information on iPSC labs on DPUK website accessible in the "For Researchers" tab then "Our Research Communities" |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.dementiasplatform.uk/our-impact/ipscs-a-shared-resource |
| Description | DPUK Whitehall cohort site visit - Jan 2020 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) and John Gallacher made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, one of them being Whitehall. This included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. In contrast to other DPUK cohort site visits, Sarah and John were invite to present at a 2 hour Whitehall group meeting with all stakeholders involved, not just the PIs. This allowed a wider engagement and awareness of DPUK's work in supporting Whitehall, and vice versa. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.ucl.ac.uk/epidemiology-health-care/research/epidemiology-and-public-health/research/whit... |
| Description | DPUK YouTube channel |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | The DPUK YouTube channel hosts video content including: -- DPUK podcasts -- Interviews with event participants -- Great Minds members' events -- Featured cohorts |
| Year(s) Of Engagement Activity | 2020,2021 |
| URL | https://www.youtube.com/channel/UC9OKgZG5Dq0RheCDV3upakw/ |
| Description | DPUK attendance to MQ Data Science meeting in Edinburgh |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sarah Bauermeister and John Gallacher attended the MQ Data Science conference meeting in Edinburgh, and event looking at bringing together researchers and innovators to explore how data science can transform how we understand, treat and prevent mental illness. John chaired a session of discussion (in the absence of Andrew McIntosh) and Sarah networked with colleagues and new audiences on the power of the DPUK Data Portal in MQ's mission. More specifically, Sarah met with Dr Gabriela Muniz-Terrera to discuss future bids and projects involving DPUK in her work. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.mqmentalhealth.org/articles/data-science-meeting-2019-agenda |
| Description | DPUK blog |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The DPUK blog features a range of articles on topics including: -- Different types of dementia -- New podcasts -- Aspects of dementia research -- Experiences of those in dementia research The blog is written in a lay-friendly style with the aim of being accessible to wider audiences. |
| Year(s) Of Engagement Activity | 2020,2021 |
| URL | https://www.dementiasplatform.uk/news-and-blogs/blog |
| Description | DPUK blog post |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Blog post about my work using the DPUK Portal and cohort data. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/blog/why-im-working-with-dpuk |
| Description | DPUK data portal presentation for ADDI workshop, Miami USA - 23/2/20 to 25/2/20 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Informative presentation for the purposes of ongoing collaborative interests. |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK data portal presentation for Alzheimer's Europe Conference 2020 (virtual), - 19/10/20 to 23/10/20 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presenting on the DPUK Data Portal. Poster presentation and booth. |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK datathon events |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk about the Deep and Frequent Phenotyping Study |
| Year(s) Of Engagement Activity | 2019 |
| Description | DPUK newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The DPUK newsletter communicates resources, data updates and funding opportunities for researchers and funders of dementia research. |
| Year(s) Of Engagement Activity | 2014,2015,2016,2017,2018,2019 |
| URL | https://www.dementiasplatform.uk/about/dpuk-newsletter-subscription-form |
| Description | DPUK newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The DPUK newsletter goes out three times a year to a distribution list of around 450 DPUK stakeholders. It provides updates on DPUK developments, research outcomes, funding opportunities etc. |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK podcast series |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This is a series of audio interviews hosted on the DPUK YouTube channel (and blog). Topics covered to date: -- DPUK's Professor John Gallacher on the future of dementia research -- What's it like to take part in a DPUK datathon? -- Increasing diversity in dementia research |
| Year(s) Of Engagement Activity | 2020,2021 |
| Description | DPUK policies |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK policy documents set out the principles underpinning DPUK's work in a number of areas: DPUK publications; intellectual property; cost recovery; data curation; data management; and data access. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/about/policies |
| Description | DPUK poster presentation: Data curation (9-11 March) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | A poster on the Data curation process presented at the Longitudinal Study conference. |
| Year(s) Of Engagement Activity | 2021 |
| Description | DPUK presentation at Oxford-PKU Joint Symposium - September 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | The Peking University Institute of Mental Health visited the Department of Psychiatry at University of Oxford for knowledge exchange. John Gallacher presented the work of Dementias Platform UK and networked with key individuals from the Chinese University, including the potential PI of a joint UK-China bid for 'Dementias Platform China'. The event lead to a strengthened application for this work. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://english.bjmu.edu.cn/academicsresearch/keyinstitutes/69.htm |
| Description | DPUK presentation on the Data Portal at the Human Ecosystem Population Cohort Workshop, Cambridge - 9/3/20 to 10/3/20 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Informative presentation for the purposes of ongoing collaborative interests. |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK representative at invitation-only UK-CRIS Research Collaboration and Networking Event - April 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sarah Bauermeister attended and supported the talks given by DPUK collaborators such as Simon Thompson, who gave a presentation on UKSeRP (which powers the Data Portal), Karen Mansfield (whose work with iSAM involves setting up a DPUK-esque database for mental health in adolescents), Dr Alejo Nevado-Helgado (lead of DPUK's WP6) and Andy Boyd (ALSPAC representative, one of DPUK's collaborating cohorts). Attending event allowed networking conversations to be centred around DPUK to relevant technological and scientific contacts, increasing relevant audience awareness, understanding and engagement. |
| Year(s) Of Engagement Activity | 2019 |
| Description | DPUK researcher blog |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | The DPUK researcher blog exists to showcase to the public the scientific activity in DPUK, prior to the reporting of key scientific findings. It exists to improve awareness of DPUK resources to researchers from a range of disciplines. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/blog |
| Description | DPUK scientific promotion and engagement at ARUK conference - March 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Sarah Bauermeister supported the DPUK Communications team in engaging attendees at the ARUK 2019 conference in Harrogate. Sarah was involved in interviews by the DPUK Communications team to promote the work of DPUK further, but also was approached by several members of the dementia community to find out more about DPUK's work, including the upcoming Datathon at the University of Exeter. One member of the DPUK Executive Team approached the stand and encouraged a live demonstration of the Data Portal. There were many requests for further information and future collaboration |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://vjdementia.com/video/ofjiuu5orkw-dementias-platform-uk-datathons-get-involved/ |
| Description | DPUK twitter account |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Through twitter, DPUK connects with the wider dementia research landscape, including policymakers, researchers and other funder organisations. Impacts are increased traffic driven to the DPUK website and increased awareness of the resources that DPUK offers the dementia research community. Comparing January 2017 with 2020 engagement increased from 0.4% to 1.6% actions (likes, retweets, link clicks etc) have increased from 19 to 759 and impressions increased from 4,410 to 77,476 |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018,2019,2020 |
| URL | https://twitter.com/DementiasUK |
| Description | DPUK update and demonstration to industry partner GSK |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Dr Sarah Bauermeister was onsite with GSK representatives to discuss data content & access to the Dementias Platform UK, with a focus on two longitudinal studies that are of interest to GSK. The agenda was: • Overview of the DPUK objectives and achievements • Outline of DPUK platform & analysis capabilities • Detailed review of data types included in the NSHD and Whitehall cohorts and what would be available to a GSK analysis team • Outline application process • Specify what can be exported post analysis, and reporting responsibilities • Agree next steps As a result GSK have been involved in further conversations with Sarah about being involved in DPUK datathons in some capacity. GSK left with a greater understanding and appreciation of what their partnership has meant for DPUK and science as a whole. |
| Year(s) Of Engagement Activity | 2019 |
| Description | DPUK virtual Datathon (1st March - 12th March) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK Datathon held online. On the topic of Logitudinal cognitive change. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dementiasplatform.uk/research-hub/data-analyst-training/dpuk-datathons |
| Description | DPUK web-based resource: Using cognitive test data |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | We provided the content for a series of webpages on the DPUK website providing helpful resources for researchers looking to assess cognitive function in their research. These will enable researchers to either select the appropriate cognitive tests for use in their planned studies or identify existing cohort data with the relevant cognitive variables for their analyses. In summary the web resource provides: 1. Key resources outlining which cognitive functions and which cognitive tests are frequently used in research with older adults 2. A downloadable directory of the cognitive tests assessed in each of DPUK's cohorts 3. Detailed reports on the psychometric work carried by WP10 on the UK Biobank cognitive assessment |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/for-researchers/dementia-research-resources/using-cognitive-test-da... |
| Description | DPUK website blog interview for data curation |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Interviewed for a blog post on the DPUK website about my role in the data curation process. The blog briefly explains a part of the process and why it is necessary. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/blog/data-curation-at-the-coalface-of-dpuk |
| Description | DPUK website blog interview on ECR journeys |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Interviewed for one of the DPUK blog posts about my journey to conducting research at Oxford and in the area of childhood adversity and brain structure. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/blog/ecr-journeys-from-teaching-english-to-exploring-the-impact-of-... |
| Description | DPUK website news section |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The news section of the DPUK website features articles about new developments in DPUK and outcomes related to the DPUK programme. |
| Year(s) Of Engagement Activity | 2020,2021 |
| URL | https://www.dementiasplatform.uk/news-and-blogs/news |
| Description | DPUK-run Cohort Metadata Workshop - Dec20 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DPUK has been invited coordinate the development of research-cohort metadata standards. John therefore invited several experts to a virtual workshop on this topic. The goal of the meeting was to leverage the experience of experts to establish a direction of travel leading to consensus on metadata standards according to data modality. At this workshop all participants will have the opportunity to present their preferred metadata model prior to a joint discussion about how metadata standards might be established. If sufficient progress was made it might provide the basis of a useful publication. Next steps agreed: - Write to John with: o Thoughts on a metadata harmonisation model and personal contribution to it o Thoughts on associated categories of use-cases for this metadata harmonisation model to drive our thinking, considering: ? One or more complex questions to be addressed (that is, exemplar researchers questions but also queries that a novice user should be able to gain answers to using said model) ? The data required to address these questions o Thoughts about a consortium across platforms where we can look at a minimal dataset to enable metadata interoperability |
| Year(s) Of Engagement Activity | 2020 |
| Description | DPUK2 TDF national workshop on Remote Cognitive Testing - Oct 2020 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | 1:00 - 1:05 Welcome and aims for the meeting Vanessa Raymont Session 1 1:05 - 1:30 The CUBOId project, Bristol Brain Centre James Selwood 1:30 - 1:55 Remote Neuropsychological Assessment, Cerebral Function Unit, Greater Manchester Neuroscience Centre Jennifer Thompson 1:55 - 2:20 Remote cognitive screening - our experience and plans with the Oxford Cognitive Screen (OCS) and OCS - Plus Nele Demeyere 2:20 - 2:45 AI in medical research, Deep Dementia Phenotyping (DEMON) Network David Llewellyn 2:45 - 3:00 Break Session 2 3:00 - 3:25 Remote Cognitive Testing from Cambridge Brain Sciences Adrian Owen 3:25 - 3:50 The Integrated Cognitive Assessment; employing AI to detect neurodegeneration Chris Kalafatis 3:50 - 4:15 The Mantrah mobile App Atreya Chaganty 4:15 - 4:40 The SharpTx mobile App Sylvain Piquet 4:40 - 5:00 Discussion and final remarks Chair - Vanessa Raymont |
| Year(s) Of Engagement Activity | 2020 |
| Description | Daily Mail press release, What the experts do to stave off dementia: After exciting new drug breakthrough, our guide to the precautions you can take to lessen your chances of the condition. 14 June 2021 What the experts do to stave off dementia | Daily Mail Online |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | media |
| Year(s) Of Engagement Activity | 2021 |
| Description | Danish Dementia masterclass |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A whole day masterclass in Copenhagen for dementia specialists across Scandinavia. I lecture, then the rest of the day in case based discussions, analysis and Q&A. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Data Science and Population Health : a Team Science Approach |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Data Science and Population Health : a Team Science Approach. Liverpool University MSc in Data Science lecture, 03/11/21. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Data Science and Population Health Research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Data Science and Population Health Research. University of British Columbia, Canada, 21/01/21 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Data linkage research- opportunities for enhanced UK/Australia collaboration |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Data linkage research- opportunities for enhanced UK/Australia collaboration, University of New South Wales, 08/11/22 |
| Year(s) Of Engagement Activity | 2022 |
| Description | Data portal workshop |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | Calvin C. (2018). Data portal workshop. Oral presentation at Dementias Platform UK Annual Conference, British Medical Association, London on 23 April 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Data reform discussion at the Royal Society |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | A roundtable discussion for data reform by the National Academy of Data, hosted at the Royal Academy. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Datathons: Alan Turing Institute, Exeter University, UEA Swansea University, Ulster University |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Researchers worked in multidisciplinary teams to analyse cohort data from selected cohorts. Outcomes were increased awareness of the Data Portal and DPUK's cohorts among a wider group of researchers, |
| Year(s) Of Engagement Activity | 2018,2019,2020 |
| URL | https://www.dementiasplatform.uk/for-researchers/data-portal-getting-started-with-cohort-data/datath... |
| Description | Daybreak Lectures on issues around dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Phillippa Carling gave a brief overview of her work on drug discovery lab at ODDI, with some videos of some of their equipment. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Dementia Advisory Group Meeting International Health Metrics/GBD |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dementia Advisory Group Meeting International Health Metrics/GBD (funded by Gates) 19 July 2019 This was the second DAG that I have attended. The first was by phone. This was in person in Los Angeles. The programme contained updates on how the GBD team at the University of Washington are synthesising evidence on dementia and creating Global metrics. The advisory panel includes individuals with very different experiences and expertise, including health economics and those who are pure epidemiologists. This meant the discussion was very rich and stimulating, and that although we are advisors we are also learning. It provided insights into the synthesis of evidence, the approaches this team teak to doing this There was lively discussion about the challenges - with aspects ranging from sociocultural context of dementia, changes across time, evidence from different fields of non communicable diseases, how to incorporate dementia associated with other conditions that are already exercises in GBD and incorporate dementia into their own outcomes (ie. Danger of double counting). The health economics remains a crude science relative to the epidemiology and for both there is a great challenge of absence of data or data that are not population representative where they do exist. I will continue to be part of this DAG, but the discussions are relevant to work for PHE and also at the national level in my work with FPH and RCP. Continue to engage where possible with these kinds of meetings where there is much mutual learning, as expressed by one of the other attendees. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Dementia Awareness Morning - Bryan Ng |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Bryan Ng helped out at a dementia awareness event at the John Radcliffe Hospital. This was a morning of talks about research into dementia in and around Oxford and a chance for the public to meet researchers and find out about support services available for people living with dementia. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.oxdare.ox.ac.uk/public-events |
| Description | Dementia Researcher Podcast: On the DPUK dataportal. - 10/10/20 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Interviewed by Dementia Researcher for a podcast released on youtube and twitter. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.youtube.com/watch?v=DXrBlNJU4oA |
| Description | Dementia Researcher Podcasts and Fundraising events - Dr M Malpetti |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | https://www.dementiaresearcher.nihr.ac.uk/tag/dr-maura-malpetti/ |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dementiaresearcher.nihr.ac.uk/tag/dr-maura-malpetti/ |
| Description | Dementia and Neurodegeneration Network Ireland (DNNI) Inaugural conference (30 November 2017) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | explore current research/future directions in the Dementia/Neurodegeneration field, effective funding models for research and the importance of interdisciplinary collaboration. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.eventbrite.ie/e/dnni-conference-2017-tickets-37728733658# |
| Description | Dementia and a Research Institute - Interview in the Sun Newspaper 5Oct15 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Publicity to promote the fact that 5p from each carrier bag bought would be donated to the Dementia Research Centre. This was the brainchild of Malcolm Walker (Iceland) with Nick Fox (DRC) |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.thesun.co.uk/sol/homepage/woman/health/health/6735025/5p-bags-could-help-combat-dementia.... |
| Description | Dementia and ageing brains: the clash of evidence, belief and policy in diagnosis and capacity to benefit in our ageing populations |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | A talk was given on 21 September 2016 at the Preventing Overdiagnosis Conference in Barcelona |
| Year(s) Of Engagement Activity | 2016 |
| Description | Dementia and brain ageing in populations |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Invited speak for Cambridge University Biological Society March 2019. Title is Dementia and brain ageing in populations. . |
| Year(s) Of Engagement Activity | 2019 |
| Description | Dementia imaging, past landmarks and future prospects', Keynote, RiiSE21 (Radiological Imaging and Intervention Symposium Edinburgh 2021) 10 April 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | Dementia: Population and Public health |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A talk was given for the visit of the DRI Direct on 19 Oct 2016 at University of Cambridge, IPH |
| Year(s) Of Engagement Activity | 2016 |
| Description | Dementias Platform UK (DPUK) Scientific Symposium |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The purpose of the Symposium was for all members of DPUK to come together to discuss and learn more about the scientific activity of the Platform, specifically looking at the main themes of Cohorts, Networks and Experimental Medicine. |
| Year(s) Of Engagement Activity | 2015,2016 |
| Description | Dementias Platform UK (DPUK) scientific symposium |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The purpose of this symposium was for all members of DPUK to come together to discuss and learn more about the scientific activity of the Platform, specifically look at the main themes of Cohorts, Networks and Experimental Medicine |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018 |
| Description | Dementias Platform UK annual conference 2017 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Delegates of DPUK's 2017 annual conference learnt about the resources available to the scientific community and initial studies which were already making use of these resources. Attendees were able to attend live practical demonstrations of the Data Portal and other free resources. Key outcomes of the day were increased awareness of DPUK's resources amongst the community of researchers based in universities and industry. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.dementiasplatform.uk/upcoming-events/event-1 |
| Description | Dementias Platform UK annual conference 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Delegates of DPUK's 2018 annual conference learnt about the resources available to the scientific community and initial studies which were already making use of these resources. Attendees were able to attend live practical workshops on the Data Portal. Key outcomes of the day were increased awareness of DPUK's resources amongst the community of researchers based in universities and industry. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/conference-2018/programme-for-the-day |
| Description | Dementias Platform UK website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The website provides general information about the DPUK project for the general public and policymakers, in addition to information for prospective industry partners in the project and an area for dementia researchers around the world to find out about the research tools and resources that are available to them through DPUK. In 2018, there were 11,000 users of the DPUK website. Comparing the last quarter of 2018 with the last quarter of 2017, we see a 97% increase in users, demonstrating dramatically increased awareness of DPUK's offer. In the last quarter of 2019 users increased by 21% to 14,460 |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018,2019,2020 |
| URL | http://www.dementiasplatform.uk |
| Description | Dementias Platform UK website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | The website provides general information about the DPUK project for the general public and policymakers, in addition to information for prospective industry partners in the project and an area for dementia researchers around the world to find out about the research tools and resources that are available to them through DPUK. |
| Year(s) Of Engagement Activity | 2016,2017,2018 |
| URL | http://www.dementiasplatform.uk |
| Description | Discussant, 39th Edinburgh Clinical Neurology Course CPC |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | Discussion on Lecanemab |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Joined an over 1000 person online Dementia Research Initiative led discussion on Lecanemab following publishing of clinical trial results. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dementiaresearcher.nihr.ac.uk/a-clinical-scientific-perspective-on-lecanemab-ukdri/ |
| Description | Do cognitive test data in UK Biobank add to prediction of incident dementia? |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | Oral presentation at Dementias Platform UK Annual Conference, Royal College of Obstetricians and Gynaecologists, London on 4 May 2017. Calvin C. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Documentary with StoryTrack on DIAN TU Filming |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | Downing Street |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Inivitation to attend reception at 10, Downing Street |
| Year(s) Of Engagement Activity | 2017 |
| Description | Dr A Tomassini talk: Postdoc Neuroscience Network Symposium, Cambridge (27th Jul '19) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | 27/07/19 - Cambridge: Postdoc Neuroscience Network Symposium (talk). https://www.eventbrite.co.uk/e/postdoc-neuroscience-network-symposium-2019-tickets-60542729935 |
| Year(s) Of Engagement Activity | 2019 |
| Description | Dr Dayne Beccano-Kelly became an international science ambassador for the World Parkinson's Congress 2022. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Dayne Beccano-Kelly became an international science ambassador for the World Parkinson's Congress 2022.Their focus leading up to the Congress is to help drive up participation of scientists to attend the WPC. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://wpc2022.org/page/2022ScienceAmb |
| Description | Dr Dayne Beccano-Kelly established the Aspiring Black Physiologists award with the Physiological Society |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | Dr Dayne Beccano-Kelly, along the Physiological Society established the Aspiring Black Physiologists award to address the disparity of black scientist in STEM research by encouraging black students at young ages to engage with and consider science research as a viable career path. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.physoc.org/careers/supporting-your-next-career-move/aspiring-black-physiologists/. |
| Description | Dr Dayne Beccano-Kelly gave a talk at the Neurodegeneration Challenge Network (NDCN) online forum funded by the Chan Zuckerberg initiative (CZI) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 10th September 2020, Dr Dayne Beccano-Kelly gave a talk at the Neurodegeneration Challenge Network (NDCN) online forum funded by the Chan Zuckerberg initiative (CZI) |
| Year(s) Of Engagement Activity | 2020 |
| Description | Dr Dayne Beccano-Kelly gave a talk at the SelectScience Virtual Neuroscience Summit 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Dayne Beccano-Kelly gave a talk at the SelectScience Virtual Neuroscience Summit 2020. The presentation tiles was 'Once upon a time at the synapse: A tale of early dysfunction in Parkinson's Disease' The presentation was recorded and featured on the Scientists' Channel: https://thescientistschannel.com/dayne-beccano-kelly |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://neurosciencesummit2020.vfairs.com/en/#home |
| Description | Dr Dayne Beccano-Kelly gave a talk on "Diversity in Teaching" to the Physiological Society as part of their webinar series |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Dayne Beccano-Kelly gave a talk on "Diversity in Teaching" by the Physiological Society He spoke about his project to make the study of physiology more appealing to BAME populations by using a competition asking participants to identify culturally appropriate role models. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.physoc.org/events/diversity-in-teaching/ |
| Description | Dr Dayne Beccano-Kelly was interviewed by Parkinson's UK about Parkinson's Research and Diversity |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | In December 2020, Dr Dayne Beccano-Kelly gave an interview to Parkinson's UK about Research and Diversity |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://medium.com/parkinsons-uk/a-researchers-view-parkinson-s-research-and-diversity-ecbee4720359 |
| Description | Dr Dayne Beccano-Kelly was recognised for his contribution to science research by University of Oxford during Black History Month: |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | During Black History Month, the University highlighted the power of excellence and academic achievement, past and present, and how the contributions of Black people have contributed to the calibre of the University's reputation. Dr Dayne Beccano-Kelly was recognised for his contribution to science research by University of Oxford during Black History Month. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://medium.com/oxford-university/the-oxford-bhm-100-7af54c5b2764 |
| Description | Dr Ellen Backhouse poster presentation on behalf of the R4VaD study team, titled 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)', UK Stroke Forum, 7th December 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster by Dr Ellen Backhouse on behalf of the R4VaD study team. 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)'. UK Stroke Forum 7th December 2020, online. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Dr Ellen Backhouse poster presentation on behalf of the R4VaD study team, titled 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)',European Stroke Organisation Conference 4th May 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster by Dr Ellen Backhouse on behalf of the R4VaD study team. 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)'. European Stroke Organisation Conference 4th May 2021, online |
| Year(s) Of Engagement Activity | 2021 |
| Description | Dr Ivan Koychev response to Science Media Centre request resulting in two interviews and articles |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Ivan's SMC quote on Aducanumab was picked up by France 24 and following this picked up a request to talk to a freelancer about sleep and dementia resulting a a short piece in the Daily Mail |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.france24.com/en/20191205-firm-behind-experimental-alzheimer-s-drug-makes-case-for-approv... |
| Description | Dr Ludovica Griffanti gave a talk at the event "Spark Joy: Organising and Writing Your Thesis". |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Dr L Griffanti gave a talk at the event "Spark Joy: Organising and Writing Your Thesis". 15th June 2020. Title: "My experience as a student, my experience as a supervisor". |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.sparkjoythesis.com |
| Description | Dr Ludovica Griffanti was featured in the OxDARE Newsletter Summer 2020 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Ludovica Griffanti was featured in the OxDARE Newsletter Summer 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.oxdare.ox.ac.uk/_asset/file/issue-10-summer-2020.pdf |
| Description | Dr M Malpetti - Host of Clinical Neurosciences Seminar & Conversation with Prof. JB Rowe |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Discussion on "From mechanisms to treatment, in disorders of frontotemporal lobar degeneration." |
| Year(s) Of Engagement Activity | 2021 |
| Description | Dr M Malpetti - Oral Presentation at Cambridge Festival 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Invited speaker at Cambridge Festival 2022, talk: "Imaging brain inflammation in dementia: an ally for future treatments" (~60 attendees - Cambridge, 01/04/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Dr M Malpetti - Scientist participant at the Dementia Research Charity #Chatathon |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Scientist participant at the Dementia Research Charity #Chatathon - online fundraising event (virtual, 02/12/2022 - https://www.dementiaresearcher.nihr.ac.uk/event/dementia-research-charity-chatathon-live/) |
| Year(s) Of Engagement Activity | 2022 |
| URL | http://www.dementiaresearcher.nihr.ac.uk/event/dementia-research-charity-chatathon-live/ |
| Description | Dr M Malpetti Invited career panel speaker at the Biomarker UCL course for PhD students |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Invited career panel speaker at the Biomarker UCL course for PhD students (London, 18/05/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Dr Maura Malpetti (Rowe Group): Oral Presentation at DPUK Translation 2023 Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation on "Post mortem validation of in vivo PET imaging: test case of inflammation in progressive supranuclear palsy" |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.dementiasplatform.uk/research-hub/translation-2023/early-career-researchers-workshop-and... |
| Description | Dr Maura Malpetti - ROWE GROUP MEMBER Invited speaker at Alzheimer's Association International Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Invited as a speaker on Brain inflammation in frontotemporal dementia. ISTAART conversation with patients and carers. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Dr Maura Malpetti - ROWE GROUP MEMBER Invited speaker at Alzheimer's RESEARCH UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | TALK TITLE: Brain imaging in dementia: for better understanding and treatment of human disease |
| Year(s) Of Engagement Activity | 2021 |
| Description | Dr Maura Malpetti - ROWE GROUP MEMBER Organizing committee member "My memory clinic and me" Cambridge Festival 2021 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | My memory clinic and me" at Cambridge Festival 2021 - a session held for those interested in neurodegenerative diseases. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://ftd.neurology.cam.ac.uk/events/201cme-and-my-memory-clinic201d |
| Description | Dr Mootaz Salman gave a talk at the Department of Stem Cell Biology- Innovative Medical Centre in Vilnius/ Lithuania. Presentation title: 3D organ-on-a-chip models to investigate CNS disorders. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 27 January 2022, Dr Mootaz Salman gave a talk at the Department of Stem Cell Biology- Innovative Medical Centre in Vilnius/ Lithuania. Presentation title: 3D organ-on-a-chip models to investigate CNS disorders. |
| Year(s) Of Engagement Activity | 2022 |
| URL | http://www.imcentras.lt/en/ |
| Description | Dr Mootaz Salman gave an in person talk as part of the DPAG Head of Department: Fellows in Pair Lecture seminar series |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 4 February, Dr Mootaz Salman gave a talk as part of the DPAG Head of Department: Fellows in Pair Lecture seminar series. His presentation title was "Defining mechanisms of blood-brain barrier dysfunction in dementia using advanced organ-on-a-chip models" |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://talks.ox.ac.uk/talks/id/bbab1b2e-6e4b-4f57-a607-4b0d58d5f419/ |
| Description | Dr Natalie Connor-Robson gave an online talk to the Parkinson's UK Henley Branch |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | On 24th February Dr Natalie Connor-Robson gave an outreach talk to the Henley Parkinson's UK Branch |
| Year(s) Of Engagement Activity | 2021 |
| Description | Dr Nora Bengoa-Vergniory & Dr Sophie Morgan gave an online presentation for the ARUK Thames Valley Network |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Due to the COVID-19 pandemic, we were unable to hold the 2020 Alzheimer's Research UK Thames Valley Network Dementia Open Morning. Over the summer presenters within the network centre who were due to talk at the March public event to give their talks online. The short talks from scientists were recorded and include a range of topics in dementia. They are available on YouTube. Sophie Morgan presentation title was 'Protein aggregation and Parkinson's disease' Nora Bengoa-Vergniory presentation title was 'Microscopic tweezers, a new avenue for treatment of neurodegenerative diseases'. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.youtube.com/playlist?list=PLPN7gkQCguDT-JdBjLXyTxJ_i7wCXhjYO |
| Description | Dr Sally Cowley gave a talk at the Cambridge Neuro Network Chan-Zuckerburg Initiative |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 22 October, Dr Sally Cowley gave a talk at the Cambridge Neuro Network Chan-Zuckerburg Initiative. Title: Modelling neuroinflammation using human induced Pluripotent Stem cell-derived microglia |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.neuroscience.cam.ac.uk/news/article.php?permalink=9c3213a467 |
| Description | Dr Sally Cowley gave a talk at the European Microglia Seminar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 2 Nivember Dr Sally Cowley gave an online talk at the European Microglia Seminar Series. Title: Modelling neuroinflammation using human induced Pluripotent Stem cell-derived microglia |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.youtube.com/watch?v=TM5VsEmt1Ts |
| Description | Dr Sarah Bauermeister comment on research into childhood adversity in Forbes |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Sarah followed up on a general request for comment from Forbes journalist and provided a telephone interview. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.forbes.com/sites/leciabushak/2020/02/11/experiencing-trauma-in-childhood-linked-to-incre... |
| Description | Dr. Nora Bengoa-Vergniory gave a Poster tour presentation at the World Parkinson's Congress, Kyoto Japan. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr. Nora Bengoa-Vergniory gave a Poster tour presentation at the World Parkinson's Congress, Kyoto Japan. Subject: CLR01 protects dopaminergic neurons in vitro and in vivo in mouse and human models |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.worldpdcoalition.org/page/PastCongresses |
| Description | Dr. Nora Bengoa-Vergniory gave a oral presentation at the Neuroscience symposium, Oxford UK (2019). |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr. Nora Bengoa-Vergniory gave a oral presentation at the Neuroscience symposium, Oxford UK (2019). |
| Year(s) Of Engagement Activity | 2019 |
| Description | Dr. Nora Bengoa-Vergniory gave an oral presentation at the Parkinson's Disease Gordon Research Conference Seminar, Maine USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr. Nora Bengoa-Vergniory gave an oral presentation at the Parkinson's Disease Gordon Research Conference Seminar, Maine USA June 23 - 28, 2019 Subject: CLR01 protects dopaminergic neurons in vitro and in vivo in mouse and human models |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.grc.org/parkinson-s-disease-conference/2019/ |
| Description | ECR DPUK Genetics Platform presentation - AAIC July 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Georgina Menzies - ECR DPUK Genetics Platform presentation - AAIC July 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | ECR Poster presentation at European Society of Human Genetics Conference 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Detelina Grozeva - ECR Poster presentation at European Society of Human Genetics Conference |
| Year(s) Of Engagement Activity | 2019 |
| Description | ECR Presentation at the MRC Oversight Board in London |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Georgina Menzies - ECR Presentation at the MRC Oversight Board in London |
| Year(s) Of Engagement Activity | 2018 |
| Description | ECR Presentations at cohort workshops - Dec 2017 and Feb 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Georgina Menzies - ECR Presentations at cohort workshops Dec 2017 and Feb 2018 |
| Year(s) Of Engagement Activity | 2017,2018 |
| Description | ECR Presentations at cohort workshops - May and September 2017 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Georgina Menzies - ECR Presentations at cohort workshops - May and September 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | EM7 NTAD featured in OxDARE (Oxford Dementia and Ageing Research) Newsletter, Summer 2019 edition |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Promotion on NTAD. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.oxdare.ox.ac.uk/_asset/file/issue-7-summer-2019.pdf |
| Description | EM7 Oxford new article 5th Feb 20 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | https://www.oxfordmail.co.uk/news/18212225.oxford-dementia-study-starts-getting-results/ |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.oxfordmail.co.uk/news/18212225.oxford-dementia-study-starts-getting-results/ |
| Description | EM7 Oxford news article 6th Feb 20 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | NTAD team contacted the local paper to publish an advertisement for recruitment to NTAD study in Oxford area. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.oxfordmail.co.uk/news/18213217.oxford-volunteers-wanted-alzheimers-brain-scan-study/ |
| Description | EU Joint Programme - Neurodegenerative Disease Research, ADDITION Consortium Kick-off meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Discussion with the initial working group of the ADDITION Consortium, regarding the DPUK Data Portal supporting the research analysis. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://portal.dementiasplatform.uk |
| Description | Early Career Researcher workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Over 40 early career researchers from universities in the UK and further afield attended a half-day workshop where they learnt about DPUK's plans for support for early career researchers and were able to give feedback and input into those plans. They also received advice on how to make successful grant applications. Impacts are difficult to measure but can be considered to be increased awareness of DPUK resources and support amongst the early career researcher community. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.dementiasplatform.uk/upcoming-events/ecr-workshop |
| Description | Eastern AHSN Neurodegeneration, Bringing academic and business communities together to improve Dementia outcomes, Cambridge 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | a cross-sector symposium on dementia research. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Editorial from Tim Greenamyre on our paper on what's wrong with Mitochondria in Parkinson's |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Editorial in Movement Disorders Journal on our publication |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.ncbi.nlm.nih.gov/pubmed/30288798 |
| Description | Eisai Ltd webinar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Invited presenter at Eisai Ltd webinar |
| Year(s) Of Engagement Activity | 2020 |
| Description | Establishment of Data Portal user group testing - assessing critical requirments |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | A meeting was organised with local Oxford Data Portal users (both within DPUK and external to the Department), plus dial-in from those in Cambridge and Edinburgh, to gain a researcher perspective on their needs from the Data Portal in order to conduct analyses. Notes were taken from the meeting, actions drawn up, and implemented for improved user experience. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://portal.dementiasplatform.uk/ |
| Description | European Brain Council Strategic Workshop (13 and 14 September 2017) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | EBC members and people working in the Value of Treatment White Paper. To explore new areas of project development for the EBC and the continuation of their Value of Treatment White Paper. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Expert at DDF Prepared Minds workshop - August 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | John was invited as an expert to contribute to the Dementia Discovery Fund (DDF)'s Prepared Minds workshop - a meeting which brought together experts in digital and functional domains of relevance for advances in patient stratification and outcomemeasures, through panel discussions, debate and presentations. They formed small groups with diverse backgrounds bouncing ideas off each other with a view to generating novel directions for developing therapeutics and/or companies. Next steps and actions from the meeting included forming a panel at the DDF Forum on this meeting's work; creating a survey and sending it to all the Pharma partners present to summarise their experience and considered merits of digital tools (and SMEs); a small working Pharma team will be assembled to co-create the product and align with the EDoN team; discussions with all key partners the structure under which this can be created e.g. a company where each founding partner invests and receives equity; regulators being involved in the design. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://theddfund.com/ |
| Description | FTD KOL meeting - University of Pennsylvania |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A meeting with KOL from academia and industry with the FDA, on new science based trials designs for FTD |
| Year(s) Of Engagement Activity | 2019 |
| Description | FTD UK Conference, Cambridge UK 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A UK wide cross sector meeting on advances in FTD, from basic science to new theapeutics |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.ftduk.org/ |
| Description | Festival of Genomics and Biodata |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented at he Festival of Genomics and Biodata |
| Year(s) Of Engagement Activity | 2022 |
| Description | Filmed Charity Broadcast for PSP Association |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | PSPA broadcast. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Fluid Biomarkers for AD, Educational Workshop, AAIC Chicago |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2018 |
| Description | Fluid Biomarkers for AD. Educational Workshop. AAIC, London |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | Formation of a Great Minds PPI panel |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Forming a PPI panel from members of the Great Minds discussion group to feedback on the registry recruitment. They provided feedback about aspects of the registry. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Formation of the Global Alliance of AD Data Management - July 2019 onwards |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | John Gallacher and Sean Hill (CAMH) recognised a need, common motivation and interest in getting common data models adopted more widely across the brain research space, and subsequently established the Global Alliance of AD Data Management, including representatives from Canada, Korea, Europe and more. There has been one face-to-face meeting and two videoconferences, with recent agreements for Oxford University to create a 'straw man' for a global model, and formation of an anaylses plan group; and IG and ethics group; federation/technical group; and funding group for further efforts. |
| Year(s) Of Engagement Activity | 2019,2020 |
| Description | Frontotemporal Dementia Support Group National Annual Seminar |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Gave a talk titled "Frontotemporal Dementia: introduction and pathways to progress" with the Rare Dementia Support Group. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=xP_yFWzb40g |
| Description | Geneva Aging Series 2017: 4th Edition on recent developments in cognitive aging: workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Invited oral presentation: Using advanced psychometric methodologies to analyse UK Biobank cognitive and mental health data, and utilising DPUK platform data. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Global Alzheimer's Advisory Board Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | Global Alzheimer's Disease Data Iniative - Interoperability Working Group, Toronto, December 2018 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presence and interaction at the 1st Global AD Data Initiative Interoperability Working Group - discussing integrating worldwide AD data platforms. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | Global Alzheimer's Disease Data Iniative - Interoperability Working Group, Washington, March 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attendance, presentation, and interaction at the 2nd Global AD Data Initiative Interoperability Working Group. Presentation of project plans and ideas to stakeholders, and involvement on debate and discussion surrounding development of initiatives. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://portal.dementiasplatform.uk |
| Description | Gordon Research Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Nora Bengoa-Vergniory "Mass-spectrometry approach highlights REST as a potential neuroprotective target for Parkinson's disease in an alpha synuclein overexpressing BAC-transgenic mouse model" Oral presentation Posters: Nora Bengoa-Vergniory, Dayne Beccano-Kelly, Natalie Connor-Robson, Rebecca Wallings |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.grc.org/parkinson-s-disease-conference/2017/ |
| Description | Great Minds - by invitation targeted website and blogs |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | Built a targeted website as part of the Great Minds pilot. AIRWAVE cohort team collaborated with us on a pilot to approach 500 of their participants and invite them to join a clinical studies register (through a paper newsletter) which will help accelerate improvements in dementia research. 45 out of 500 participants have registered their interest to be part of clinical studies and trials for dementia as part of Great Minds. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.greatmindsfordementia.uk/ |
| Description | Great Minds discussion panel (PPI) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | The Great Minds discussion group met at the MRC to shape the development of the registry recruitment website. They provided feedback on the process of joining the Great Minds register, the risks and benefits involved in becoming a member of the register, and the approach and language used to describe membership of the register |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.greatmindsfordementia.uk/how-it-works/about |
| Description | Guardian Discussion on "How the brain ages, and what can be done to ameliorate normal cognitive decline?" |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | 24 November 2022: Conversation with Ian Sample, Science Editor for the Guardian "How the brain ages, and what can be done to ameliorate normal cognitive decline?" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Guest blog Dr Luke Whiley on Dementia Researcher |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Luke Whiley, now a lab lead in Australia, est out for ECRs how 'One small DPUK grant can kick-start a big career' |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dementiaresearcher.nihr.ac.uk/guest-blog-one-small-dpuk-grant-can-kick-start-a-big-caree... |
| Description | Guest speaker at Alzheimer's Society Dementia Cafe |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Sana Suri - Talk: guest speaker at Alzheimer's Society Dementia Cafe, Oxford September 2017: "The heart-brain link in dementia" |
| Year(s) Of Engagement Activity | 2017 |
| Description | HDR UK Science Strategy Board presentation - January 2020 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation to the HDR UK Science Strategy Board related to the planned multi-omics implementation project and general UK-wide research infrastructure in health data science. |
| Year(s) Of Engagement Activity | 2020 |
| Description | HDR UK Scientific Strategy Board presentation - November 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation to the HDR UK Scientific Strategy Board related to national health data science infrastructure, the possibility of a network infrastructure for a 'Cohorts' Digital Innovation Hub, and future plans for federated analyses across national and international platforms. |
| Year(s) Of Engagement Activity | 2019 |
| Description | HDRUK QQR2 Public Health Research Vision |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | HDRUK QQR2 Public Health Research Vision. HDRUK national meeting, 26/04/21 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Health Canal article based on HDAC4 paper |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Online news article on HDAC4 paper based on Parkinson's UK press release |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.healthcanal.com/brain-nerves/parkinson/247111-experimental-cancer-drug-shows-promise-for... |
| Description | Health Data Research UK Site Meeting - January 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Presentation and discussion of the DPUK Data Portal as an affiliate partner of Health Data Research UK. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://portal.dementiasplatform.uk |
| Description | Health and Care Research Wales Public Engagement talk 2016 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Institute of Psychological Medicine and Clinical Neurosciences staff at Cardiff University School of Medicine were required to attend a one hour presentation on the importance of engaging with the public in scientific research. The aim was to give staff a greater appreciation of public involvement, and the benefits of this in research. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.healthandcareresearch.gov.wales/involving-the-public-in-your-research |
| Description | Health or illness, person or patient: Blurring the lines in the development of pre-symptomatic biomarkers for dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Atkinson, S., 'Health or illness, person or patient: Blurring the lines in the development of pre-symptomatic biomarkers for dementia'. Invited Symposium Paper, Navigating Impasses in Bioethics: Rethinking Ill/Health 2015, Von Hügel Institute, St Edmund's College, University of Cambridge, Cambridge, UK. Audience: Public health, bioethics of public engagement and recruitment. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Hosted 'Brain Banking at scale: A DPUK Next Generation Workshop' |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Post mortem examination provides the most accurate method available for obtaining accurate dementia diagnosis. Well characterised brains, those with detailed contextual data, provide greater opportunity for new insights to be gained on the causes of dementia. DPUK cohorts provide a reservoir of highly informative brains with up to 60 years lead-in data and genotyping being available. A DPUK actuarial analysis has shown that during the next 10 years an estimate of 6,500 brains with donor consent and the support of surviving family from UK Biobank alone, is not unreasonable. DPUK has already developed a consent protocol for selective brain collection, but is not aware of consensus on how to cost-effectively collect brain tissue at scale. To consider how to collect brain tissue at scale we invited several dementia research leaders in London for a one day workshop. During the day, participants representing a range of disciplines were given an opportunity to suggest the donor selection criteria, tissue type, and collection and storage requirements they would find most informative. From this, consensus on a strategy that might be implemented. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/upcoming-events/brain-banking-at-scale |
| Description | Hughes - CBU Open Science Workshop 2016, Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK (2016) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Hughes, L. (22nd November 2016). CBU Open Science Workshop 2016, Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK. |
| Year(s) Of Engagement Activity | 2016 |
| Description | I'd be OK getting the letter, I still would need to discuss it first |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Atkinson, S., et al. '"I'd be OK getting the letter, I still would need to discuss it first": Ethical considerations for recruitment from existing studies to dementias research. Poster Presentation, Alzheimer's Society Annual Conference, London, UK. Audience: Public health, bioethics of public engagement and recruitment. |
| Year(s) Of Engagement Activity | 2017 |
| Description | IASIS: Big Data for Precision Medicine, Plenary Meeting, March 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attendance and interaction at the IASIS plenary meeting. DPUK is supporting IASIS on data access and to discuss integration of the IASIS tools to the DPUK Data Portal. The tools comprise discovery tools, data subset selection mechanisms and data analysis pipelines. The two pilot use cases for the IASIS tools are analysis of dementia outcomes, and lung cancer. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://project-iasis.eu/ |
| Description | IHCC Education webinar on impact of COVID-19 on global mental health |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attending and participating in a webinar for an IHCC project involving global inpact of the pandemic on mental health. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://ihccglobal.org/ |
| Description | IHCC Summit meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A presentation on global mental health project during the pandemic for a global summit. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://ihccglobal.org/ |
| Description | IHCC presentation at webinar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Presentation on the mental health impact of COVID at an IHCC virtual workshop. |
| Year(s) Of Engagement Activity | 2021 |
| Description | IMI-EMIF Symposium Brussels |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster: Predictors of Successful Cognitive Aging in European Superagers (90+ Years): A Cross-Platform EMIF & DPUK Investigation of Real-World Evidence: Bauermeister et al. (Presented by Jansen, W.) |
| Year(s) Of Engagement Activity | 2018 |
| Description | Impact across the platform: Perspective of an ECR |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation at Dementias Platform UK Annual Conference |
| Year(s) Of Engagement Activity | 2018 |
| Description | In Conversation at Christmas - Broadcast on Dementia |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | In conversation at Christmas is a stimulating discussion, covering some of the progress made in research in 2022, and looking ahead to 2023. Hear from our Chief Scientific Officer, Prof James Rowe and Head of Research, Dr Rosa Sancho and ambassador for Alzheimer's Research UK, Scott Mitchell. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.youtube.com/watch?v=Vwp8QNIJSZ4 |
| Description | In Conversation: Memory Matters at Cambridge Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Memory Matters An unforgettable conversation with the memory clinic as part of the Cambridge Festival |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://ftd.neurology.cam.ac.uk/events/cambridge-festival-event-memory-matters |
| Description | In February 2022, Prof Richard Wade-Martins gave a talk at the Oxford-Harrington Rare Disease Centre Hosts Live Webinar for Rare Disease Day |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | On 28 February 2022, Prof Richard Wade-Martins gave a talk at the Oxford-Harrington Rare Disease Centre Live Webinar to celebrate Rare Disease Day. The live webinar was titled, 'Advancing Novel Treatments for Neurological Rare Diseases'. The webinar featured a panel of experts discussing areas of unmet needs in Neurological Rare Diseases, Rare Cancers, and Rare Developmental Disorders. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.harringtondiscovery.org/news-media/2022/02/08/oxford-harrington-rare-disease-centre-host... |
| Description | Inaugural Fellowship to Charmaine Lang paves the way to improved human models for Parkinson's drug discovery |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Charmaine Lang has been awarded the first jointly funded Senior Research Fellowship from Parkinson's UK and Rosetrees Trust. With this award, Dr Lang will develop complex new induced pluripotent stem cell (iPSC) models that target the interaction between dopamine neurons and astrocytes in the brain and how these fail in the context of Parkinson's. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.dpag.ox.ac.uk/news/inaugural-fellowship-charmaine-lang-improved-human-models-parkinsons-... |
| Description | Informatics for Health 2017 - Showcasing of DPUK Portal at the Swansea University stand - 24/4/17-26/4/17 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Informatics for Health 2017 - Showcasing of DPUK Portal at the Swansea University stand - 24/4/17-26/4/17 |
| Year(s) Of Engagement Activity | 2017 |
| Description | Insight 46 launch facebook offices |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Talk sparked questions and included George Freeman MP - Minister for Life Sciences A number of members of the audience asked for further information |
| Year(s) Of Engagement Activity | 2015 |
| Description | Institute of Genetics and Biophysics, Naples, Italy |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | In March 2022, Professor Richard Wade-Martins gave a talk at the Institute of Genetics and Biophysics, Naples, Italy |
| Year(s) Of Engagement Activity | 2022 |
| Description | Insurance United Against Dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Alzheimer's Society Insurance United Against Dementia campaign dinner - aim to formally launch IUAD partners to senior figureheads from the insurance industry Used as an opportunity to thank existing IUAD partners and inspire potential partners to make a contribution. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Integrated Academic Training Symposium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave a talk entitled "Prediction and Prevention in Neurodegenerative disease" in which I spoke of the Deep and Frequent Phenotyping study |
| Year(s) Of Engagement Activity | 2019 |
| Description | Interactive workshop on "The Upside-down Brain" at the Ashmolean museum |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Sat 18 March, All day The Upside-Down Brain: Art and Neuroscience at the Ashmolean Family Friendly Event. Naiara Demnitz |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.google.co.uk/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0ahUKEwjE172jjO... |
| Description | International Dominantly Inherited Alzheimer's Disease Family Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | International Population Data Linkage Network Conference - Banff, Canada, September 2018 - Data Services presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Laura North presented on the data curation and preparation services offered by DPUK to enhance cohort data usability and integrity. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | International Population Data Linkage Network Conference - Banff, Canada, September 2018, Data Portal presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Infrastructure presentation on technical and data integration of the DPUK Data Portal |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | International Society FTD Conference - "Magnetoencephalography (MEG) and frontotemporal dementia' |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The International Conference on Frontotemporal Dementias (ICFTD) is l recognized as the primary venue for the synthesis, exchange, and dissemination of research evidence related to FTD, where experts from diverse backgrounds share recent discoveries, insights, and opinions. The talk presented hilighted our groups experiences with applying MEG methods to FTD patients in early research trials. |
| Year(s) Of Engagement Activity | 2021 |
| Description | International Women's day video for DPUK |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Contributed to a video about Women in Science for the DPUK platform as apart of international women's day |
| Year(s) Of Engagement Activity | 2020 |
| Description | International alpha-synuclein meeting, Leuven, Belgium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In April 2022, Professor Richard Wade-Martins was the opening speaker at the International alpha-synuclein meeting in Leuven, Belgium |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.kuleuven.be/brain-institute/events-and-outreach/synuclein-2022-meeting |
| Description | Interview for Good Morning Britain TV Channel - Dementia Support |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | Interview for Terry Jones Passing Away - Radio 5 live |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | Interview for UKDRI news and events |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Spotlight on Prof Valentina Escott-Price |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://ukdri.ac.uk/news-and-events/spotlight-on-prof-valentina-escott-price |
| Description | Interview for national news/promotion of science - Sarah Bauermeister Hearing Aid Cognitive Decline article in the Daily Mail |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Scientist at DPUK) was interviewed as part of her research work into the potential preventative power of hearing aids against more rapid cognitive decline - the article gained strong engagement on DPUK twitter, promoting the success of DPUK and the valuable outputs it can bring to the public. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dailymail.co.uk/sciencetech/article-9266541/Health-Hearing-aids-delay-dementia-onset-peo... |
| Description | Interview given by OPDC student to the Dept of Physiology, Anatomy & Genetics, University of Oxford describing NIH-OxCam: a graduate student's journey to Oxford |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Stewart Humble talks i dpeth about his personal experience and how he came to join the Wade-Martins Lab from Louisiana State University Health Sciences Center in New Orleans as part of the National Institutes of Health Oxford-Cambridge Scholars Programme (NIH-OxCam), an accelerated, individualised doctoral training programme, to help him make the transition to a Physician-Scientist career path. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dpag.ox.ac.uk/news/nih-oxcam-a-graduate-students-journey-to-oxford |
| Description | Interview in Civil Service Fast Stream blog - How Stem Cells Can Boost Our Knowledge and Understanding of the Causes of Dementia |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | This is the third and final in a series of interviews carried out by a group of civil servants that have dedicated time to raising money and awareness for dementia via 'The Fund', a Fast Stream initiative. Alison Leishman, Home Office, interviewed Professor Wade-Martins about his research into dementia. Richard discussed OPDC and the DPUK. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://faststream.blog.gov.uk/2016/05/20/the-fascinating-world-of-research/ |
| Description | Interview: Women in Science podcast on behalf of DPUK senior data manager. - 8/1/21 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | An interview for the Women in Science podcast (gov.uk) Sarah Bauermeister as senior scientist and data manager of DPUK. (yet to be released). |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited as key contributing stakeholder to Dementia Discovery Fund Annual Forum (2019) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | John Gallacher was invited as a key stakeholder to DDF's Second Annual Forum to review progress in novel dementia therapeutics. The Dementia Discovery Fund ("DDF" or "the Fund") welcomed more than 100 key stakeholders to its Annual Forum to discuss the opportunities and challenges surrounding the development of high-impact therapeutics for age-related dementias. Established in 2015, DDF is the world's only global venture capital fund dedicated to delivering both high-impact therapeutics for age-related dementias and financial returns by investing in, creating, and supporting innovative companies. The Annual Forum, now in its second year and attended by representatives from innovative research companies, academia and the investment community, welcomed presentations from emerging companies who are supported by DDF investment and who are pursuing the development of highly promising and differentiated novel therapeutics and platforms in dementia. There are now 4 products in clinical testing from two of the companies. Panel sessions also explored wider themes impacting the discovery and development of novel therapeutics including the design and funding of clinical trials and the use of behavioural phenotyping to determine progression and outcomes in dementia patients. The Forum also heard personal perspectives from a Champion for Alzheimer's Research UK. Angus Grant, CEO of the Dementia Discovery Fund, said: "The insights and perspectives gained from this year's Forum are vital as we continue to provide investment in, and support to, innovative companies pursuing cutting-edge therapeutic approaches to change the course of dementia. Hearing of the latest progress from world-leading clinicians and scientists, and of the human impact of dementia from those personally affected, only reaffirm the importance of this fund in accelerating new treatments to tackle what remains the one of the greatest global healthcare challenges of our time. "The Dementia Discovery Fund has made significant progress this year strengthening and diversifying its portfolio of investments in novel dementia therapeutics. I am hopeful that as we continue our strategy of investing in cutting-edge therapeutic approaches, we can change the course of dementia." Since completing its fundraising in 2018, with £250 million ($350 million at the time of completion) raised from an influential group of strategic investors, the DDF has made significant progress building its portfolio of investments. To date, around £150m has been invested, committed and reserved by the Fund, with 17 companies and projects currently active in the portfolio. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://theddfund.com/ddf-hosts-second-annual-forum-to-review-progress-in-novel-dementia-therapeutic... |
| Description | Invited delegate World Dementia Council Summit |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Expert panel on current state of dementia research and impact, globally. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited expert to selective scoping meeting re: challenges of an ageing society in the UK and China |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | John Gallacher was invited to participate as an academic delegate, with colleagues invited by the National Science Foundation China (NSFC) to help scope and prioritise thematic areas for a joint research call between UKRI and NSFC. He was suggested to them by their colleagues at MRC (Medical Research Council). The primary focus of the workshop was to examine the challenges of an ageing society in the UK and China and will took place in Beijing on Tuesday 25th and Wednesday 26th June 2019. The objective of the workshop was to identify potential research themes which are of interest to both UK and China researchers, so as to inform the development of a prospective research funding call in this area. They anticipated approximately 20-25 participants (around 12 each from both the UK and China). The workshop focused on inclusive ageing and understanding new health and social risks in the UK and China. John was unable to attend himself, but suggested Dr Sarah Bauermeister as a worthy representative of DPUK in his place. Sarah gave a presentation to those attending on DPUK and its Data Portal, and was barraged by several requests for collaboration. Indeed, some of these requests turned in a formal bid with Chinese Co-Is in relation to the aforementioned ESRC call, one particularly around the establishment of a 'Dementias Platform China' |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://esrc.ukri.org/funding/funding-opportunities/ageing-in-the-uk-and-china/ |
| Description | Invited guest to results presentation of Million Women study, a DPUK cohort |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | Sarah Bauermeister was invited by the PI of the Million Women study (a DPUK cohort) to present recent results from from the Study and an update on the AgeX breast screening trial. One of the talks was centred around dementia and how the study supported, and can support, research in these area. The invitation to the meeting demonstrated the Study's appreciation of DPUK in their work, but also offered an opportunity to strengthen relationships with the cohort going forward, which in turn could lead to fruitful advances in data availability and access. Sarah and John were welcomed for a more Data Portal-specific Million Women Site Visit a few months later, to discuss the platforms benefits and capabilities. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.millionwomenstudy.org/introduction/ |
| Description | Invited member of Polygenic Risk Scoring Expert Panel |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited member of Polygenic Risk Scoring Expert Panel for Illumina company, Batimore, USA |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation to the UK Sports Concussion Research Symposium - November 2018. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Increased awareness of benefits of longitudinal studies |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.drakefoundation.org/ukscr/ |
| Description | Invited seminar at Icahn School of Medicine at Mount Sinai |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited seminar at Icahn School of Medicine at Mount Sinai, NY, USA |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited session chair at Alzheimer's Association International Conference 2021, USA - Dr M Malpetti |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chaired session on "Neuroimaging: Molecular Imaging of Novel Biomarkers for Neurodegeneration and ADRD" session at AAIC 2021 (07/2021 - Denver USA) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited speaker at 7TMRI group University of Cambridge- Dr Amirhossein Jafarian |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Title: Prior in DCM and MRS informed dynamic causal modelling. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited speaker at Alzheimer's Research UK conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited speaker at Alzheimer's Research UK conference, Harrogate UK |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited speaker to FBRI Alzheimer's Disease Workshop |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited speaker to FBRI Alzheimer's Disease Workshop, Boston, USA |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited talk "Integrating neuroimaging datasets: approaches for the harmonisation of white matter hyperintensity measurements", ADNI MRI Core meeting 21st December 2021 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited talk "Integrating neuroimaging datasets: approaches for the harmonisation of white matter hyperintensity measurements", Alzheimer's Disease Neuroimaging Initiative (ADNI) MRI Core meeting 21st December 2021. In the main focus of the presentation was the harmonisation approaches used in our recent Neuroimage paper (https://www.sciencedirect.com/science/article/pii/S1053811921004663?via%3Dihub). It also mentioned newer approaches under development at the Wellcome Centre for Integrative Neuroimaging (WIN), Oxford. The presentation sparked very useful discussions about the harmonisation needs and challenges of ADNI, to guide future directions of harmonisation techniques. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited talk "Structural MRI analysis with FSL", part of the educational webinar "Software for image analysis" organised by the NeuroImaging Professional Interest Area from the Alzheimer's Association ISTAART |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | The webinar "Software for Image Analysis" on Thursday May 27, 10am-12pm US ET and was organised by the NeuroImaging Professional Interest Area from the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) It included five speakers from the software tools SPM (J. Ashburner), FSL (L. Griffanti), FreeSurfer (J.E. Iglesias) and Nipy (A.Rana, S. Gosh) providing an introduction to their specific software. The event registered 177 viewers from 28 countries over 5 continents. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.alz.org/research/for_researchers/grants/research-webinars |
| Description | Invited talk - British and Irish Hypertension Society - Annual Scientific Meeting, Barbican, York, 12-14 September 2022. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk by Professor Joanna Wardlaw - "BP in cerebral small vessel disease and vascular dementia" British and Irish Hypertension Society - Annual Scientific Meeting, Barbican, York, 12-14 September 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk - Veterinary Diagnostic Imaging annual meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Imaging for human dementia" European College and the European Association in Veterinary Diagnostic Imaging annual meeting, Edinburgh, Scotland, 15 September 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk at UK Stroke Forum.Liverpool, England, 29 November-01 December 2022. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk by Professor Wardlaw - "Can we prevent progression of cerebral small vessel disease" UK Stroke Forum.Liverpool, England, 29 November-01 December 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited to talk at the ARUK Dementia Research Day - Dr. Nora Bengoa-Vergniory |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 31July 2019, was invited to talk at the ARUK Dementia Research Day. Subject: CLR01 protects dopaminergic neurons in vitro and in vivo in mouse and human models |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invitee to NIHR's Dementias Portfolio Development Group (PDG) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | The Dementias Portfolio Development Group (PDG) is composed of experienced researchers from diverse disciplines and lay members within the dementia field that promote the development of innovative ideas into funded research. The remit, structure and governance of the Dementias PDG are somewhat similar to their predecessor, the Clinical Studies Groups. Broadly, it includes identifying research gaps as well as supporting Writing Groups to formulate and prepare grant applications for clinical studies and health and social care research; including research conducted outside of NHS settings. John Gallacher is a regular invitee to NIHR's Dementias Portfolio Development Group (PDG), which involves updates from the chair, ARUK, AlzSoc and other scientists. |
| Year(s) Of Engagement Activity | 2018,2019,2020 |
| URL | https://www.nihr.ac.uk/documents/dementias-portfolio-development-group/11672 |
| Description | Item Response Theory for Assessing Individual Change |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | The IRT course was run on 30 August 2019 at the University of Edinburgh. We had ~25 attendees from across the UK. The intention of the course was to provide an introduction to some advanced statistical methodologies applicable to the study of individual change in ageing research, with a view to improving the general practice in the field through engagement with ECR's in the use of open source software. The course was well received and was highly enjoyable to teach. |
| Year(s) Of Engagement Activity | 2019 |
| Description | JGallached contribution to Oxford University Dementia Strategy - Bio-banking and Clinical Studies/Epidemiology |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Dementia Working Group 4 - Bio-banking and Clinical Studies/Epidemiology. Work in response to the anticipated increased in governmental funding into dementia researc following press releases. Collaboration with leading experts with aims to produce a centrally produced report. |
| Year(s) Of Engagement Activity | 2020 |
| Description | JGallacher MRC Leaders Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Attendance and contribution as representative from DPUK. |
| Year(s) Of Engagement Activity | 2020 |
| Description | JGallacher as Chair - Arts4Dementia Roundtable 6May2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | 2.15 Veronica Franklin Gould, President, Arts 4 Dementia. Social prescribing, best mechanism to refer patients from surgery to "arts prescription" to combat the isolating trauma of dementia pre-diagnosis. 2.20 Keith Oliver, Alzheimer's Society ambassador, living with young onset Alzheimer's. 2.25 John Daniel and Dr Jane Spiro, Preserving cultural skills and experience. 2.30 CHAIR: Professor John Gallacher, Professor of Cognitive Health at the University of Oxford and Director of Dementias Platform UK (DPUK) 2.35 Alexandra Coulter, Chair, Culture Health & Wellbeing Alliance, Director of Arts & Health South West Social Prescribing: Primary Care: 2.40 Sir Muir Gray CBE, Visiting Professor, Value Based Healthcare, Nuffield Department of Primary Care Health Sciences, University of Oxford. 2.45 Dr Richard Kimberlee, Nat. Social Prescribing Network, University of West of England 2.50 Dr Stephanie Tierney, Oxford Social Prescribing Network, Researcher in Evidence Synthesis at the Centre for Evidence-Based Medicine, Nuffield Health Sciences. Training: 2.55 Dr Bogdan Chiva Giurga, Founder NHS England Social Prescribing student scheme. (medical students in attendance) 3pm Maria Parsons, Director, Creative Dementia Arts Network Social Prescribing & Arts prescriptions suited to people with early signs of dementia: 3.05 Tim Joss, Chief Executive, Aesop 3.10 Angela Conlan, Dance Practitioner, Dance Creative, Creating with Care 3.15 Lucy Shaw, Head of Programmes & Partnerships, University of Oxford's Gardens, Libraries & Museums (GLAM) 3.20 DISCUSSION Making it Happen for Dementia: 3.30 Dr David Chapman, Mental Health Clinical Lead Oxfordshire CCG, Clinical Lead Oxford City 3.35 Emma Fuller, Clinical Lead, OxFed Social Prescribing Service. 3.40 Dr Rupert McShane, Consultant psychiatrist. Head of Oxfordshire Memory Clinic, Warneford Hospital. 3.45 Jane Probets, Lead Dementia Adviser, Oxford City, Dementia Oxfordshire. 3.50 Stephen Chandler, Head of Adult Services, Oxfordshire County Council & NHS Oxfordshire CCG & ADASS National Policy Lead for Mental Health. 3.55 Ian McCreath, Personalisation Lead, Alzheimer's Society, NHS England #DCAN 4 pm Jennifer Neff, Co-Founder, Elemental Software, digital social prescribing platform. 4.10 DISCUSSION Ends 4.20 (Zoom will stay open until 4.45 for further discussions, if required) VERONICA FRANKLIN GOULD FRSA founded Arts 4 Dementia (A4D) in 2011 to develop weekly programmes for early-stage dementia at arts venues, training, best practice conferences and reports. Reawakening the Mind (2012-13) won the London 2012 Inspire Mark and Positive Breakthrough in Mental Health Dementia Award 2013. On publication of Music Reawakening (2015), Veronica was appointed A4D president. Her regional guide, Reawakening Integrated: Arts & Heritage (2017), maps arts opportunities for dementia and aligns arts within NHS England's Well Pathway for Dementia. Veronica leads A4D's social prescribing programme. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://arts4dementia.org.uk/our-presidents-blog/ |
| Description | JGallacher as member of SAIL Scientific External Advisory Board |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | John Gallacher provided his expertise in data management and access to the SAIL SEA Board. |
| Year(s) Of Engagement Activity | 2020 |
| Description | JGallacher as speaker - NIHR BRC Multi-morbidity & Long Term Conditions: Digital Health & Dementia Workshop |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Summary: The NIHR Oxford BRC Multi-morbidity & Longterm Conditions theme (based in the Nuffield Department of Primary Care Health Sciences, University of Oxford) hosted a workshop on November 5, to generate collaborative research ideas. The research area of focus was Digital Health & Dementia within the context of primary health care. We wanted to explore how to: Explore how to build on existing activity to use digital health more effectively in dementia • To examine dementia as part of multi-morbidity • To identify opportunities for cross-cutting projects The speakers and their presentations were: Arlene Astell Technology Transforming Dementia Jane Fossey Digital Health and Dementia Vanessa Raymont Remote cognitive assessments - need and reality John Gallacher Data integration for early detection of dementia TingTing Zhu Digital Health & Dementia (Engineering Dept) Ben Goldacre OpenSAFELY |
| Year(s) Of Engagement Activity | 2020 |
| Description | JGallacher attendance - Future research in COVID-19 brain pathology workshop - Dec2020 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | 14:00-14:05 Welcome - Colin Smith: Director of the MRC UK Brain Bank Network 14:05-14:15 Introduction and setting the scene - Safa Al-Sarraj: Director, King's College London Brain Bank First session: Acute Covid19 brain pathology (Chair: Colin Smith and Claire Troakes) 1. 14:15-14:30 ACE2 receptors and ARS role in COVID-19 brain pathology Scott Miners (Bristol University) 3. 14:30-14:45 COVID-19 cerebrovascular disease: the pathogenesis: Raj Kalaria (Newcastle Brain Bank) 4. 14:45-15:00 COVID-19 encephalitis: Safa Al-Sarraj (King's College London Brain Bank) 5. 15:00-15:20 Identification of SARS-Cov2 in brain tissue: Clayton Wiley (Pittsburgh, USA) / Markus Glatzel (Neuropathology, Hamburg, Germany) Break 15:20-15:30 Second session: Patient recruitment and Autopsy examination (Chair: Safa Al-Sarraj) 1. 15:30-15:45 Post-mortem and recruitment of autopsy brain examination: Mike Osborn and Brian Hanley (Royal College of Pathologists and Department of Pathology Imperial College London /Charing Cross hospital): 2. 15:45-16:00 Recruitment of autopsy brain examination: The German experience Markus Glatzel (Neuropathology, Hamburg, Germany) Third session: Long term impact of COVID-19 on brain pathology (Chair: Seth Love) 1. 16:00-16:15 Auto immune aspects of COVID-19 brain pathology: Javier Alegre-Abarrategui (Imperial College Brain Bank) 2. 16:15-16:30 COVID-19 Cerebrovascular disease: the clinical view: David Werring (Neurology: University College London) 3. 16:30-16:45 Cognitive impact of COVID-19: Seth Love (Bristol Brain Bank) 4. 16:45-17:00 Neuropsychiatry of COVID-19: Tim Nicholson (Biomedical Research Centre, South London and Maudsley Hospital Trust/King's College London) 17:00-17:30 Discussion and agreement on areas for future research (Colin Smith, Claire Troakes and Safa Al-Sarraj) |
| Year(s) Of Engagement Activity | 2020 |
| Description | JGallacher contribution to UK Biobank Steering Committee |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | John contributed his expertise from his lessons learned of DPUK and in cognitive testing for the ongoing development of the cohort UK Biobank. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/governance/steering-committee |
| Description | JGallacher invited to Population Research UK development meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Invitation: ESRC, Health Data Research UK, MRC and Wellcome invite you to join a launch webinar commencing the development phase of Population Research UK, a planned new research infrastructure that maximises the insights, innovations and research efficiency of the UK's wealth of social and biomedical longitudinal population studies. PRUK is set to be a national data infrastructure with significant investment. PRUK will complement and learn from existing research infrastructures, in an interdisciplinary way to combine the biomedical, social and economic sciences. PRUK will focus on increasing access of data to new and potential users across academia, public bodies, charities and industry, and providing services and expertise to users that facilitates their research. PRUK will support current LPS through tackling, jointly, challenges in data curation, linkage and analytics, and create research efficiencies from doing things on behalf of the community that can benefit all. In partnership with the LPS community, public, study participants and all interested stakeholders, HDR UK are commencing, on behalf of the three funders, a design and dialogue programme to further develop and refine the aims, activities and structure of PRUK. Following the design and dialogue programme, it is expected a funding Call will be announced jointly between the three funders in autumn 2021 for leadership and partners to deliver PRUK. ESRC, HDR UK, MRC and Wellcome are hosting a launch webinar on Wednesday 16th December at 11am. Please sign up to learn more about PRUK and ways to engage with the design and dialogue programme. Actions and Minutes ?The Partnership Group members described the different research infrastructures and initiatives to which they were associated. ?The Partnership Group discussed the terms of reference and the relationship of the Partnership Group to the Progamme Board. The terms of reference of both groups are included in Annex 1. ?The commitment to the Partnership Group being transparent in its activity through making minutes of its meetings and key papers available was discussed and endorsed by the membership. ?There was discussion about the best way for interested stakeholders to engage and it was agreed that the stakeholder community be encouraged to contact the HDR UK team centrally via the details on the HDR UK website in the first instance rather than Partnership Group members individually. ?HDR UK and the research funders presented a slide set providing an overview of the ambitions of PRUK and its proposed activities as well as the planned design and dialogue programme. The updated slide set 'Launching the Development of Population Research UK' is available on the HDR UK Population Research UK webpage. ?Partnership Group welcomed and endorsed the ambition of the ESRC, MRC and Wellcome to fund jointly a longitudinal population studies resource. ?It was clarified that the aim of PRUK was to be an enabling initiative and resource for longitudinal population research. PRUK was not to be a research project. ?HDR UK explained that the structure of PRUK had yet to decided. It was to be informed by the design and dialogue phase. PRUK may be single entity or could function as a more distributed structure. ?It was clarified that PRUK was a continuation of previous discussions facilitated by ESRC, MRC and Wellcome to create 'Population Research Resource' (PRR). ?The Partnership Group provided helpful feedback on the slide set. HDR UK agreed to update the slides in response to these points ahead of tomorrow's webinar. These changes are reflected in the publicly available copy of the slide set. ?The Partnership Group also provided recommendations of areas for further development for PRUK through the design and dialogue phase. These covered: o Additional clarity on the scope of PRUK - in particular coverage beyond Longitudinal Population Studies - so as to focus on something ambitious but achievable o The public value of the proposition. In other words, a 'mission' focus where benefit and research questions enabled by PRUK are described o Defining success criteria for PRUK and gap analysis on what is not currently in place o The positioning of PRUK to other initiatives with functionality, services or data relevant to the proposed operating space of PRUK o Options on the structures of PRUK and the incentives to encourage studies to join o The importance of involving other funders outside of those currently represented o Joining up with any existing public engagement initiatives and ensuring it was clear what is already decided and what is being consulted on ?HDR UK thanked the Partnership Group for their input and agreed to take the recommendations as actions for further development. ?The next Partnership Group meeting would be scheduled for early February. ?The Chair thanked the group for their participation and closed the meeting. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.hdruk.ac.uk/population-research-uk-email-sign-up/ |
| Description | JGallacher invited to provide DPUK expertise to UK Dementia Ecosystem meeting Jan20 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Context The COVID-19 pandemic has created significant, unexpected challenges for those suffering with dementia, carers and dementia researchers across the entire pre-clinical and clinical spectrum. We cannot lose momentum - while promising vaccines will help push back against Covid-19 over the next year, dementia will still remain one of our biggest long-term health challenges, and Covid-19 will exacerbate these challenges. Following up on the initial meeting in 2019, the UK DRI is gathering again 'UK Dementia Ecosystem' representatives and other key stakeholders in a virtual roundtable discussion to share perspectives, reflect on the impact of Covid-19 on dementia research and care and identify opportunities to accelerate our progress in tackling dementia. Agenda 15:00 - 15:05 Welcome and aims of the event Prof. Bart De Strooper, UK DRI Director 15:05 - 15:20 Impact of COVID-19 on dementia research - an overview Prof. Martin Rossor, NIHR National Director for Dementia Research 15:20 - 16:10 Roundtable discussion 1 - Neurological Effects of COVID-19 Chair: Prof. James Rowe, Dept Clinical Neurosciences, Cambridge - NIHR Cambridge BRC Academic Lead, DPUK Associate Director (Experimental Medicine Incubator) Discussants (5-7 min each): • Clinical and biomarker profiles of neuro-COVID Dr. Ross Paterson, UCL Queen Square Institute of Neurology • The COVID-19 Clinical Neuroscience Study (COVID-CNS) Dr. Benedict Michael, University of Liverpool Discussion questions: - What do we know right now about the neurological/neuropsychiatric effects of COVID-19? - How has COVID-19 impacted on those with incipient or frank dementia? (initiated delirium/dementia or exacerbated symptoms) - Is 'Long COVID' a feature of those with incipient or frank dementia or are distinct pathways involved (cf genetics of Long COVID patients)? 16:10 - 16:20 Break 16:20 - 17:20 Roundtable discussion 2 - Impact of COVID-19 on research and care: lessons learnt and future opportunities Chair: Prof. David Sharp, Director of UK DRI Care Research & Technology Director at Imperial College London Discussants (5-7 min each): • Harnessing large population studies to study the impact of COVID on dementia risk Prof. Paul Matthews, Director of UK DRI at Imperial College London • Learning from COVID-19 to improve dementia care Prof. David Sharp, Director of UK DRI Care Research & Technology Director at Imperial College London • Impact of COVID-19 on dementia care Prof. Alistair Burns, National Clinical Director for Dementia and Older People's Mental Health, NHS England • Experimental medicine after COVID-19 - challenges and opportunities Prof. Patrick Chinnery, MRC Clinical Director Discussion questions: - What is the impact of COVID-19 on the way we do research and care for those suffering with dementia? - Are there any 'lessons learnt' from the COVID-19 crisis that can help accelerate our progress in understanding dementia and improve care? (e.g. shed light on how infection can exacerbate disease, more effective collaboration, pooling cohort data, remote care technologies etc.) - What are the implications for future strategic initiatives in this space? 17:20 - 17:30 Concluding remarks Confirmed participants Prof. Dag Aarsland NIHR South London & Ma |
| Year(s) Of Engagement Activity | 2020 |
| Description | JGallacher invited to talk - Rosetrees Interdisciplinary Workshop on neurodegenerative diseases of the brain - Feb20 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | National interdisciplinary workshop on neuro-degenerative diseases of the brain, funded by Rosetrees Trust and the UKRI Physics of Life network plus https://www.physicsoflife.org.uk/ The aim of all the workshops funded by the PoL/Rosetrees network is to stimulate interdisciplinary approaches. John was invited to present on 'Multi-modal data integration and Dementias Platform UK'. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.physicsoflife.org.uk/neurodegenerative-disease.html# |
| Description | JGallacher member of External Advisory Committee tor Krembil Centre for Neuroinformatics. |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | John Gallacher provided his expertise in data management, access and collection from DPUK to this Canadian institute. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.camh.ca/en/science-and-research/institutes-and-centres/krembil-centre-for-neuroinformati... |
| Description | JGallacher presentation at D-TRC Steering Group 7Oct20 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | John Gallacher aided discussions on how we can improve links between the D-TRC, the DEMON network and DPUK. |
| Year(s) Of Engagement Activity | 2020 |
| Description | JGallacher speaking - MRC Human Brain and Nervous Tissue Resource workshop - Nov20 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Chair: Professor Paul Matthews, Imperial College London, Chair MRC Neurosciences and Mental Health Board. Research involving human brain and nervous tissue remains essential to support cutting edge discovery and translational science, to validate findings from model systems and ultimately advance understanding of human brain disorders. Aligning closely with this, the MRC Neurosciences and Mental Health Board (NMHB) has identified research providing 'Insight into the Living Human Brain' as a priority area. To better understand the human brain in detail, the Board recognises the need to gain comprehensive knowledge of human neural and glia cell biology, circuitry and function spanning different levels of spatial and temporal resolution. The research landscape together with approaches to using human tissue have evolved considerably over the last decade. These changes have largely been driven by the development of novel methods and technologies, the emergence of data-rich neuroscience platforms and a greater emphasis on interdisciplinary science to accelerate innovation. In addition, the scale and depth of digital health-related data has expanded exponentially in recent years. This includes the wealth of nationally collated NHS healthcare datasets and large-scale national investments to establish population-based collections such as UK Biobank and the Accelerating Detection of Disease programme. Strategic investment in a national brain and nervous tissue resource will be key to facilitating state-of-the-art and innovative research across the breadth of the neurosciences and mental health community, enabling the UK to maintain a leading international position in this area. Aims of workshop: • Bring together experts in the neuroscience and wider research community to discuss current and emerging needs that should be addressed in a new strategy for tissue resourcing. • Use examples of prominent international resources and initiatives to inform participant consideration and discussion on approaches to the provision and use of human brain and nervous tissue |
| Year(s) Of Engagement Activity | 2020 |
| Description | JGallacher talk at event - UK Dementia Care Research Summit - Achievement, collaboration and innovation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Third sector organisations |
| Results and Impact | John Gallacher gave a talk at UK the Dementia Care Research Summit - Achievement, collaboration and innovation in Leeds. The aim of the Summit was to reflect on the progress we have made, take stock of where we've got to now, and set out plans and ambitions for the next decade. The format of the day was plenty of punchy short presentations along with small group and wider group discussion to set out new directions. John spoke in the Session Sharing on research data, where the aim was to explore how we can collaborate better on dementia care research data. He spoke about the contribution initiatives he is involved in. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.alzheimers.org.uk/for-researchers/uk-dementia-care-summit-2020-looking-forward |
| Description | Jack FM (Oxford radio station) interview on My Beautiful Brains Project |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | An interview on the Oxford Radio station Jack FM, about the My Beautiful Brains project. Working with the Black Dementia company to host support workshops for people from minority backgrounds. |
| Year(s) Of Engagement Activity | 2022 |
| Description | James - Presentation to the British Heart Foundation. October 2018. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | James SN presented on Investigating risk factors for dementia: Over 65 years of follow-up in the 1946 Birth Cohort. Presentation to the British Heart Foundation. October 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | James et al - Information stall at the ARUK UCL network public engagement called Meet the Scientist. October 2018. |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | James SN, Lu K, Carr H, Popham M - all gave information on Insight 46: Scanning people in the longest-running British Birth Cohort. Information stall at the ARUK UCL network public engagement called Meet the Scientist. October 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | James, AAIC London (2017) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Sarah James submitted an abstract and gave a presentation at AAIC London (2017) entitled, "Midlife affective symptoms are associated with lower brain volumes in later life: evidence from a prospective UK birth cohort". This presentation sparked questions and discussion amongst attendees of the conference. |
| Year(s) Of Engagement Activity | 2017 |
| Description | James, British Heart Foundation, 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Sarah James was invited to give a presentation at the British Heart Foundation in October 2018. The presentation was entitled, "Investigating risk factors for dementia: Over 65 years of follow-up in the 1946 Birth Cohort." |
| Year(s) Of Engagement Activity | 2018 |
| Description | James, UK Frontiers in Traumatic Brain Injury Conference, 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Sarah James was invited to give a presentation at the UK Frontiers in Traumatic Brain Injury Conference in July 2018. The presentation was entitled, "Traumatic brain injury with loss of consciousness and subsequent cognitive trajectories." |
| Year(s) Of Engagement Activity | 2018 |
| Description | James, UK Sports Concussion Research Symposium, 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Sarah James was invited to give a presentation to the UK Sports Concussion Research Symposium in November 2018. The presentation was entitled, "What have we learnt about longitudinal studies?". |
| Year(s) Of Engagement Activity | 2018 |
| Description | John Gallacher - talk at Army and Navy Club, London, on Stress, Health and Happiness |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Presentation to older generation of public surrounding brain health, inspired discussion and requests for presentation afterwards. |
| Year(s) Of Engagement Activity | 2019 |
| Description | John Gallacher comment in The Times on Johnathan Schott research into relationship between cognition in childhood and cognition after 60 years old |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | John Gllacher commented on the reach of Johnathan Schott into cognition and the Insight 46 cohort. This was on the front page of The Times on 31 Oct 2019 |
| Year(s) Of Engagement Activity | 2019 |
| Description | Joint Programme for Neurodegenerative Disease (JPND) Scientific Advisory Board (SAB) strategic workshop on precision medicine (13 March 2017) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The purpose of the workshop is to bring together clinicians, basic scientists and industry scientists to examine how the precision/stratified medicine concept can be applied to neurodegenerative disease research. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Keshavan - Poster presented at the UCL Queen Square Symposium 2018. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | Keshavan presented on Exploring the role of blood-based biomarkers for Alzheimer's disease in a pre-clinical cohort: Insight 46 - The Neuroimaging Sub-study of the MRC National Survey of Health and Development. Poster presented at the UCL Queen Square Symposium 2018. Increased awareness of importance and impact of work amongst colleagues |
| Year(s) Of Engagement Activity | 2018 |
| Description | Key contributor to UK Biobank's Re-Imaging Stakeholder Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | John was contacted by the Chair of the UK Biobank Imaging Working Group to contribute to the Re-Imaging stakeholders meeting. With MRC support directed to it by the Dementias Platforms UK, UK Biobank has begun to re-image 10,000 of the Imaging Enhancement participants with an interval of approximately 2 years. The UK Biobank Steering Group now is developing a plan to allow re-imaging of an additional 60,000 subjects following the end of the cross-sectional imaging of the full cohort of 100,000. The inter-scan interval for this would be staggered between approximately 2-7 years across the cohort. This re-scanning could start as soon as late 2021. The imaging protocol being performed now would be repeated for re-imaging. However, as the re-scanning would be planned with a lower daily subject throughput (e.g., 15 rather than 18 subjects per day), there is an opportunity for some additions to the scanning or evaluation protocol at the Centre. Although funding for enhancements to the re-imaging protocol has not been identified, now is the time for the scientific community to help UK Biobank consider what would be of value. An open meeting was held on Friday 6th December in London to solicit views from the community and discuss how recommendations for alternative enhancements should be prioritised. Several ideas were proposed by working "sub-groups" coordinated by IWG modality leads, including those related to heart, brain, abdomen and bones as well as non-imaging phenotype measures (grip strength etc). Measures in each of these categories were discussed in terms of what could be easily implemented, of high priority, of value and of interest. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Key note (debate) RCPsych Faculty of Neuropsychiatry conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | Keynote invited speaker, Genetics and epigenetics of mental disorders international conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Keynote invited speaker, Genetics and epigenetics of mental disorders international conference, St Petersburg 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Keynote speaker at The University of Reading SIAM-IMA student chapter conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Undergraduate students |
| Results and Impact | Keynote speaker at The University of Reading SIAM-IMA student chapter conference, Reading, UK. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Keynote speech Sutcliffe Kerr Lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Keynote speech at annual Walton Centre, Sutcliffe Kerr Lecture |
| Year(s) Of Engagement Activity | 2019 |
| Description | Labmate article: Cutting-edge brain imaging technology |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Labmate commission this article as a result of the press pack from the DPUK 5 year celebratory event. The article focused on DPUK's national imaging network and the harmonisation work. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.labmate-online.com/article/news-and-views/5/dementias-platform-uk/changing-dementia-hori... |
| Description | Lane, AAIC Chicago (2018) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Chris Lane submitted an abstract and gave a presentation at AAIC Chicago (2018) entitled, "Influences of blood pressure and blood pressure trajectories on cerebral pathology - results from a British birth cohort". This presentation sparked questions and discussion amongst attendees of the conference. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Large Clinical populatin based studies as sources for big datasets |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Schools |
| Results and Impact | Was part of a conference and the session before mine was on imaging. This was a nice update on imaging work in Germany. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Late night event at The Science Museum |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Leading a seminar at Queen's University Belfast |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Sarah Bauermeister lead an afternoon DPUK-branded talk and seminar entitled 'accelerating research through cohort data' to 20+ students on the techniques and capabilities available. The co-director of ARK passed on afterwards to Sarah that a member of the Men's Health Forum was at a meeting about men and dementia in Armagh (about 50 miles away) a few days later, and two people at the meeting (one from a local council, and another from a Men's Shed) were talking about the wonderful seminar they had been at Queen's the day before, and how great the speaker was. It was good to hear how useful they found it, especially when they are from quite different backgrounds and they had travelled quite a way to get to the seminar. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://twitter.com/S_Bauermeister/status/1181911959295447041 |
| Description | Lecture on "Introduction to Neuroimaging" at MRC CBU Course - Dr M Malpetti |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture on the "Introduction to Neuroimaging" course at the MRC Cognition and Brain Science Unit, University of Cambridge (Cambridge, 06/02/2023): "PET imaging" |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://imaging.mrc-cbu.cam.ac.uk/methods/IntroductionNeuroimagingLectures |
| Description | Lecture to MPhil Students in Basic and Translational Neuroscience - Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture on the MPhil in Basic and Translational Neuroscience, University of Cambridge (Cambridge, 24/10/2022): "Dementia and neurodegenerative diseases: what have we learned from brain imaging?" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Lecturing as part of Oxford University's MSc in Non-communicable diseases - neurodegenerative conditions with a focus on dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecturing as part of Oxford University's MSc in Non-communicable diseases - neurodegenerative conditions with a focus on dementia - asked to lecture at a Chinese university exchange summer school and engage more with life at the host college (St Edmunds Hall). |
| Year(s) Of Engagement Activity | 2018 |
| Description | Lu - Presentation at UCL Queen Square Symposium 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | Lu presented on Visuomotor integration in Insight 46, a neuroscience sub-study of the MRC National Survey of Health and Development. Presentation at UCL Queen Square Symposium 2017. Increased awareness of important work amongst colleagues. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lu, Queen Square Symposium, 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Kirsty (Macpherson) Lu made a presentation at the Queen Square Symposium in May 2017. During the symposium, she described preliminary results of visuomotor integration in Insight 46. |
| Year(s) Of Engagement Activity | 2017 |
| Description | MEGUK Oral Presentation by Dr Amirhossein Jafarian (Rowe Group) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave an oral presentation titled Multimodal Dynamic causal modelling |
| Year(s) Of Engagement Activity | 2021 |
| Description | MRC 10 year Showcase |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | An academic afternoon sharing our latest findings and results of the research undertaken over the last 10 years of the centre. Followed by an evening panel event with Mike, James and Anita chaired by the VC and joined by Robin Buckle of MRC. |
| Year(s) Of Engagement Activity | 2019 |
| Description | MRC CBU Science Night - Cambridge Science Festival 2019 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Demonstrations of research studies, including VR game |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.mrc-cbu.cam.ac.uk/blog/2019/01/mrc-cbu-science-night-cambridge-science-festival-2019/ |
| Description | MRC CNGG/NCMH/CADR stand at the Wales Gene park's Genetics and Genomics Conference |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Representatives from the Alzheimer's Genetics Team manned a stand at the Wales Gene Park's Genetics and Genomics Conference on 22nd June, 2016. A number of individuals were interested in discussing the research environment, and how participants could help with discovery science. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.eventbrite.co.uk/e/genetics-and-genomics-for-the-3rd-generation-tickets-24871582573 |
| Description | MRC Dementias Platform UK WP10: Examination of the psychometric properties of UK Biobank cognitive tests |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation at Dementias Platform UK Annual Conference |
| Year(s) Of Engagement Activity | 2017 |
| Description | MRC's The Source interview with John Gallacher - December 2020 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The Source is run by MRC's internal communications officer. John Gallacher was interviewed on the below: Content • Start with an introduction into DPUK, who you are and what the role of DPUK is • 3 main themes will lead the questions - the past, present and future o What were your biggest achievements over the last 5 years? o What will the next phase of DPUK look at now you have received renewal of funding? o What does this mean for the future of dementia? Are you hopeful? This interview shone a light amongst close MRC colleagues of the value and success of the work they have helped fund. |
| Year(s) Of Engagement Activity | 2020 |
| Description | MS Society Public Event |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | A presentation to members of the MS Society |
| Year(s) Of Engagement Activity | 2016 |
| Description | Making game changing improvements in the health of patients and populations |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Adelaide University, Australia |
| Year(s) Of Engagement Activity | 2018 |
| Description | Mark Kelly Parkinson Voice Project lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Mark Kelly spoke at a Parkinson Voice Project lecture presented in the Clark and Brigid Lund Parkinson's Education Center. The talk was streamed live and is available online. This lecture explores what we know so far about impulse control behaviours in Parkinson's and takes a look at work being carried out by the Oxford Discovery Project to better understand these effects. This knowledge helps not only in better directing available therapies, but also improves our understanding of some of the underlying pathological processes involved in Parkinson's. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.opdc.ox.ac.uk/impulse-control-behaviours-and-creativity-in-parkinson-s |
| Description | Marta Madureira - abstract submitted to conference, & selected to give a Short Talk at the EMBO Autophagy Workshop, August 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Marta Madureira from the Wade-Martins lab submitted an abstract to the EMBO Autophagy conference and was selected to give a short talk at the Workshop in August 2019 |
| Year(s) Of Engagement Activity | 2019 |
| Description | Medical Express article on HDAC4 paper |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Article on HDAC4 publication based on Parkinson's UK press release. Medical Xpress is a web-based medical and health news service that is part of the renowned Science X network. Based on the years of experience as a Phys.org medical research channel, started in April 2011, Medical Xpress became a separate website. Branching out with Phys.org's monthly 2.5 million readership, Medical Xpress features the most comprehensive coverage in medical research and health news in the fields of neuroscience, cardiology, cancer, HIV/AIDS, psychology, psychiatry, dentistry, genetics, diseases and conditions, medications and more. Readers of Medical Xpress will have access to the same features offered on Phys.org, such as article comments, ranking, the ability to save favorite articles, a personal account page, easy sharing, podcasts, iPhone/iPad/Android apps and other options. Readers may follow Medical Xpress on Facebook, Twitter or through a variety of customizable RSS feeds and e-Newsletter for the latest in medical research and health news. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://medicalxpress.com/news/2018-12-experimental-cancer-drug-parkinson.html |
| Description | Medical Genetics Section Talk, IGMM, University of Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Research talk to postgraduate students and researchers in the Medical Genetics Section of the Institute for Genetics and Molecular Medicine, University of Edinburgh. The research plan was discussed and refined. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Medicine and Me: Living well with Dementia |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Giving a talk on types and diagnosis of dementia at this half day meeting. The Medicine and Me series of meetings at the RSM aim to update on important conditions and gives a direct voice to patients and their carers to air their concerns on the impact of diagnosis, investigation and management. Physicians and surgeons and indeed all healthcare professionals continue to learn from and be inspired to greater efforts by our patients to improve care. The audience at this meeting will comprise of those living with dementia, their families, carers and advocates, representing about 70% of those present; and clinicians and researchers, representing not more than 30%. Clinicians will include doctors, specialist nurses and others involved in the treatment and care of those who have this condition |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.rsm.ac.uk/events/events-listing/2015-2016/groups/public-engagement-programme/mmg01-medic... |
| Description | Meeting the Challenge of Dementia: DPUK Report 2020 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In October 2020, DPUK launched a new report summarising its achievements to date and looking ahead to its future role at the leading edge of dementia research. Titled 'Meeting the challenge of dementia', the report showcases DPUK activity across a number of key areas: -- Addressing the challenge presented by dementia to societies around the world in the 21st century. -- Early detection of disease through innovative platforms like the DPUK Data Portal and DPUK's imaging and stem cell networks. -- Matching public volunteers with the right dementia studies and trials. -- Experimental medicine studies to illuminate the cellular and neurological mechanisms behind dementia. -- Collaboration with industry, third sector and academic partners around the world. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://review2020.dementiasplatform.uk/ |
| Description | Meeting with ARUK representatives re: strengthening DPUK and EDoN relationship |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Third sector organisations |
| Results and Impact | Sarah Bauermeister and John Gallacher met with Rafa Jimenez (Head of Research Informatics at ARUK) to discuss collaboration with DPUK and the charity regarding the soon to be announced Early Detection of Neurodegeneration initiative. As a result of these proactive conversations, and more down the line, DPUK has been announced as an official partner of EDoN and mentioned in several engagement activities (press releases etc) as a result. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://edon-initiative.org/ |
| Description | Meetings with Insight46 donors via ARUK |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Meeting with Insight46 donors via ARUK to discuss Insight46 and dementia research. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Member of the SAIL Scientific External Advisory Board and their meetings |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Involved in the discussions for DPUK as a strategic partner for SAIL, as well as a member of the closed external advisory group evaluating SAIL - reviewing its primary focuses, the current landscape its in, and international development. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://saildatabank.com/ |
| Description | Member of the Scientific Advisory Board of the Bordeaux Population Health research center (BPH) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | John Gallacher was invited as part of a small panel to take part in a mid-term assessment of the BPH as part of a Scientific Advisory Board. The SAB tried to see where they are today, both for the BPH globally and for the different teams, and to offer his opinion and insights on the scientific strategy and his suggestions for evolutions for the new project. It involved reviewing both the overarching strategy as well as the work of individual research groups. BPH is run by the Director Prof Carole DuFouil, an esteemed colleague of DPUK as PI of a collaborating cohort. This SAB meeting provided useful insight into the international landscape that DPUK could fit in as well as crystallising important working relationships. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.bordeaux-population-health.center/en/ |
| Description | Member of the governance, design and delivery strategy groups for the MS Society |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Member of the governance, design and delivery strategy groups for the MS Society. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.mssociety.org.uk/ |
| Description | Michele Hu - Talks to Oxford and Milton Keynes Parkinson's UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Michele Hu Talk to loacal Parkinson's UK branches |
| Year(s) Of Engagement Activity | 2016,2017 |
| Description | Mind over Chatter Podcast: Dementia |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | What causes dementia? And how do we diagnose and treat it? Is there anything we can do to stop ourselves from developing dementia? These are the crucial questions we'll be exploring with clinical neuropsychologist Barbara Sahakian, sociologist Richard Milne, and neurologist James Rowe. In this episode, we'll find out more about what dementia actually is, some surprising factors that increase a person's risk of developing dementia, and computer games that can actually help detect and diagnose dementia. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://podcasts.apple.com/gb/podcast/dementia-risks-diagnosis-and-prevention/id1542332564?i=1000549... |
| Description | Mission Possible Gala Dinner - Fundraising for the Rare Dementia Centre |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | Monthly attendance a the Parkinson's UK Oxford branch meetings |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | During 2022, members of the Wade-Martins lab attend in person the monthly Parkinson's UK Oxford Branch meetings to meet with PWP. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://oxfordparkinsons.org.uk/ |
| Description | Mootaz Salman appointed Departmental Research Lecturer |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In December 2021, Dr Mootaz Salman was conferred the title of Departmental Research Lecturer in recognition of his contribution to his research group and the teaching and research mission of DPAG. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dpag.ox.ac.uk/news/mootaz-salman-appointed-departmental-research-lecturer |
| Description | More than a pub initiative |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Gave a public talk in my local community based on research carried out from the DPUK platform |
| Year(s) Of Engagement Activity | 2019 |
| Description | Murray-Smith H - Presentation at the Leonard Wolfson Experimental Neurology Centre Training Day. June 2015. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Undergraduate students |
| Results and Impact | Heidi Murray-Smith presented - The MRC National Survey of Health and Development (NSHD) Neuroimaging Sub-study: INSIGHT 46. Presentation at the Leonard Wolfson Experimental Neurology Centre Training Day. Increased awareness of work amongst colleagues. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Murray-Smith, Leonard Wolfson Experimental Neurology Centre International Clinical Trials Day, 2015, Poster |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Heidi Murray-Smith presented a poster, "A longitudinal amyloid-PET/MRI study of the MRC NSHD British 1946 birth cohort", at the 2015 Leonard Wolfson Experimental Neurology Centre (LWENC) International Clinical Trials Day. This poster provided an opportunity for the general public, patients at the LWENC, carers, and practitioners to ask questions about Insight 46. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Murray-Smith, Leonard Wolfson Experimental Neurology Centre Training Day, 2015 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Heidi Murray-Smith gave a presentation, "The MRC National Survey of Health and Development (NSHD) Neuroimaging Sub-study: INSIGHT 46", to the staff of the Leonard Wolfson Experimental Neurology Centre about the Insight 46 study and the progress to date. The presentation took place in June 2015. |
| Year(s) Of Engagement Activity | 2015 |
| Description | My Memory Clinic and Me |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Presented at an event titled My Memory Clinic and Me as part of the Cambridge Festival in March 2021. The Cambridge Memory Clinic provides assessment and management for a wide range of memory and cognitive disorders, for example, due to neurodegeneration (Alzheimer's disease, Mild Cognitive Impairment, Frontotemporal dementia, Dementia with Lewy Bodies) and more. A discussion was help about memory clinics in the context of dementia. How they can help, and what to expect - including their role in leading research that matters to patient care. Short presentations followed by a live Q&A session with consultant neurologists. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://ftd.neurology.cam.ac.uk/events/201cme-and-my-memory-clinic201d |
| Description | NBA Annual Lecture - Members Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | NHS Digital Collaboration Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Meeting with NHS Digital to discuss infrastructure solutions for DPUK cohorts, and wider onward sharing to the UKSeRP infrastructure tenants. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | NHS Lothian Annual Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Clinical Research : driving efficient, innovative and effective healthcare. |
| Year(s) Of Engagement Activity | 2016 |
| Description | NICOLA and PRIME DPUK site visits - October 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Dr Sarah Bauermeister (Senior Data Manager) made several site visits to our DPUK cohorts across the country to provide updates on ongoing developments and plans for DPUK2, two of them being NICOLA and PRIME. The visit included an overview presentation and a Data Portal demonstration showcasing updated DPUK data visualisation tools as part of ongoing website and Data Portal developments. They also shared more information about the DPUK datathon programme, the 3-day datathon workshops utilising cohort data within the Data Portal at host institutions. These events are attracting multi-disciplinary researchers and encouraging collaborative research opportunities to take forward to full DPUK proposals. Post-event, NICOLA and Prime had a better understanding and awareness of the benefits that DPUK and its Data Portal could bring to the cohort and analysis of its data. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://portal.dementiasplatform.uk/CohortDirectory/Item?fingerPrintID=NICOLA&tabid=Built%20Environm... |
| Description | NTAD volunteer request advert in local news |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Call for volunteers for NTAD Oxford arm of study. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dementiasplatform.uk/news-and-blogs/news/brain-study-pinpointing-early-signs-of-alzheime... |
| Description | National Advertising Campaign with Alzheimer's Research UK |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | National advertising campaign |
| Year(s) Of Engagement Activity | 2021,2022 |
| Description | Nature Neuroscience Interoperability Meeting, Toronto, December 2018 - Data Portal presentation and panel appearance |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A technical presentation on the DPUK Data Portal, followed by an appearance on the data platform panel, answering policy and practice questions from an expert meeting audience |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://portal.dementiasplatform.uk |
| Description | Nesbit - Talk presented at the meeting on "Your ageing brain. Use it or loose it". Meeting by Sevenoaks and Knole U3A Science Groups (2016) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Nesbit, D. (7th June, 2016). Talk presented at the meeting on "Your ageing brain. Use it or loose it". Meeting by Sevenoaks and Knole U3A Science Groups |
| Year(s) Of Engagement Activity | 2016 |
| Description | Neurogune talks, Bilbao Spain |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | "Alpha-synuclein overexpressing mice and protection of neurons from synuclein toxicity by molecular tweezers" Oral presentation Nora Bengoa-Vergniory |
| Year(s) Of Engagement Activity | 2017 |
| Description | New Alzheimer's risk genes discovered in record study |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | A press release was issued highlighting the discovery of 11 new susceptibility genes for AD by the IGAP consortium. Details of these findings were published by all of the main UK news organisations. |
| Year(s) Of Engagement Activity | 2013 |
| URL | http://www.cardiff.ac.uk/news/articles/new-alzheimers-risk-genes-discovered-in-record-study-11975.ht... |
| Description | New Atlas online article on HDAC4 press release |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Article on HDAC4 paper based on the press release from Parkinson's UK |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://newatlas.com/experimental-cancer-drug-parkinsons/57481/ |
| Description | New item: New study shows clinical symptoms for Alzheimer's can be predicted in preclinical models |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A new collaborative study from the University of Oxford has demonstrated that clinical vulnerability to an abnormally abundant protein in Alzheimer's brain is in fact reflected in individual patient induced pluripotent stem cell-derived cortical neurons. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dpag.ox.ac.uk/news/new-study-shows-clinical-outcomes-for-alzheimers-can-be-predicted-in-... |
| Description | News Article featuring the winners of the DPAG Student Poster Day 2021 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | In November 2021, there was a news article featuring the winners of the DPAG Student Poster Day 2021. One of the runners up was Tara Diviney from the Wade-Martins lab. Tara Diviney, supervised by Dr Natalie Connor-Robson, Professor Stephanie Cragg and Professor Richard Wade-Martins, with "Characterisation of a novel GBA-L444P BAC transgenic mouse model of Parkinson's disease". |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dpag.ox.ac.uk/news/winners-of-the-dpag-student-poster-day-2021-announced |
| Description | News Item: Charmaine Lang appointed Departmental Research Lecturer |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Charmaine Lang has been conferred the title of Departmental Research Lecturer in recognition of her contribution to her research group and the teaching and research mission of DPAG. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dpag.ox.ac.uk/news/charmaine-lang-appointed-departmental-research-lecturer |
| Description | News article as researchers from the OPDC and the Wade-Martins Group move |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In June 2021, researchers from the OPDC and the Wade-Martins Group recently moved to brand new laboratory facilities at the Kavli Institute for NanoScience Discovery. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dpag.ox.ac.uk/opdc/news/latest/new-laboratory-facilities-for-opdc-researchers |
| Description | News article on DPUK website |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | News article entitled "PhD student develops new tool to make studying brain waves easier and more accurate" on DPUK website news section. The article describes a new tool and publication linked to Dementia research. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dementiasplatform.uk/news-and-media/latest-news/phd-student-develops-new-tool-to-make-st... |
| Description | News article on cognition research |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.healthline.com/health-news/dementia-can-be-detected-early |
| Description | News article on cognition research |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.news-medical.net/news/20220110/Poor-cognition-may-be-part-of-normality-in-older-age-rese... |
| Description | News article on how cognitive frailty may be part of normal aging |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://talker.news/2022/01/11/elderly-people-can-show-signs-of-mental-decline-without-getting-demen... |
| Description | News article on how cognitive frailty may be part of normal aging |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://allmymedicine.com/health-news/predicting-alzheimers-risk-how-useful-are-cognitive-tests/ |
| Description | News article on how cognitive frailty may be part of normal aging |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.medicalnewstoday.com/articles/predicting-alzheimers-risk-why-cognitive-testing-alone-may... |
| Description | News article on how cognitive frailty may be part of normal aging |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://en.brinkwire.com/health/alzheimers-disease-isnt-always-caused-by-cognitive-decline/ |
| Description | News article on how cognitive frailty may be part of normal aging |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.thehealthnewsexpress.com/alzheimer_disease_dementia/cognitive-decline-not-always-a-sign-... |
| Description | News article on how cognitive frailty may be part of normal aging |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.medica-tradefair.com/en/News/News_from_the_Editors/Cognitive_decline_not_always_a_sign_o... |
| Description | News article on how cognitive frailty may be part of normal aging |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The recent publication titled "Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease" was featured on a health website suggesting that poor cognition may be part of normality in older age. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://scitechdaily.com/cognitive-decline-is-not-always-a-sign-of-alzheimers-disease/ |
| Description | News article to celebrate building of new laboratory space for OPDC Researchers |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | A news article celebrate a major building in the centre of Oxford has been constructed to create a new research centre bringing together cellular neuroscience and physical sciences. Members of the OPDC will move into the new building. Known as the new Kavli Institute for NanoScience Discovery (Kavli INSD), the building will uniquely combine structural biology with world-leading biochemistry, pathology, chemistry, physics, physiology and engineering. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dpag.ox.ac.uk/opdc/news/latest/new-laboratory-space-for-opdc-researchers |
| Description | News article to celebrate research success in World Parkinson's Month April 2020 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | In April 2020, a news article was published to celebrate research success in World Parkinson's Month |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dementiasplatform.uk/news-and-blogs/news/world-parkinsons-month-frontier |
| Description | News article to promote the Wade-Martins Group achieving Bronze award for sustainable practices |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In October 2021, the Wade-Martins Group achieved a Laboratory Efficiency Assessment Framework (LEAF) Bronze award in recognition of its sustainable practices. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dpag.ox.ac.uk/news/wade-martins-group-achieves-bronze-award-for-sustainable-practices |
| Description | News item: Fellowship awarded to Mootaz Salman could pave the way for early intervention in Parkinson's |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Mootaz Salman has been awarded a Leverhulme Trust Early Career Fellowship - a highly prestigious, fiercely competitive research award with just 145 awards available nationally this year across all disciplines. These fellowships enable early career academics to undertake a significant piece of publishable work. Dr Salman is now pursuing a 3-year research project entitled "Targeting mechanisms of blood-brain barrier dysfunction in Parkinson's using humanized 3D brain-on-a-chip models", on which he will work independently within DPAG in close collaboration with the Wade-Martins Group. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dpag.ox.ac.uk/news/fellowship-awarded-to-mootaz-salman-could-pave-the-way-for-early-inte... |
| Description | News item: Oxford Parkinson's Disease Centre awarded £3.8 million to reveal the role of calcium in Parkinson's |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Researchers at the Oxford Parkinson's Disease Centre led by Professor Richard Wade-Martins with Professor Stephanie Cragg and Professor Peter Magill, have been awarded a £3.8 million Wellcome Trust Collaborative Award in Science to study the critical role of calcium in the biology of dopamine neurons. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dpag.ox.ac.uk/news/opdc-awarded-3-8-million-to-reveal-the-role-of-calcium-in-parkinsons |
| Description | News item: The Wade-Martins Group achieved a Laboratory Efficiency Assessment Framework (LEAF) Silver award in recognition of its sustainable practices. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The Wade-Martins Group has achieved a Laboratory Efficiency Assessment Framework (LEAF) Silver award in recognition of its sustainable practices. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dpag.ox.ac.uk/news/wade-martins-group-attain-silver-sustainability-award |
| Description | News of a major new $9 million project funded by the Aligning Science Across Parkinson's (ASAP) initiative |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In October 2021, it was announced that a major new $9 million project funded by the Aligning Science Across Parkinson's (ASAP) initiative will map the original circuits vulnerable to Parkinson's on an unprecedented scale. The project is a collaboration between core investigators Stephanie Cragg, Richard Wade-Martins, and Peter Magill at Oxford, Mark Howe at Boston University and Dinos Meletis at the Karolinska Institutet, as well as collaborators Yulong Li at Peking University and Michael Lin at Stanford University. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dpag.ox.ac.uk/news/mapping-uncharted-networks-in-the-progression-of-parkinsons |
| Description | News story about OPDC's Natalie Connor-Robson engagement work on widening access to STEM skills with In2scienceUK |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | OPDC Career Development Fellow Natalie Connor-Robson shares STEM career advice with students taking part in the In2scienceUK programme. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.opdc.ox.ac.uk/opdc-s-natalie-connor-robson-widens-access-to-stem-skills-with-in2scienceu... |
| Description | News story about a collaborative study led by the OPDC's Dr Nora Bengoa-Vergniory |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | News story about a collaborative study led by the OPDC's Dr Nora Bengoa-Vergniory that has shown that compounds known as molecular tweezers could become a promising disease modifying therapy for Parkinson's. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.opdc.ox.ac.uk/tiny-brain-tweezers-could-hold-the-key-to-treat-parkinson-s |
| Description | News story and video featuring the Wade-Martins lab to mark World Parkinson's Day |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | News story to mark World Parkinson's Day, featuring a video with an inside look into the Wade-Martins Laboratory. The Wade-Martins Group conducts critical research into several neurodegenerative diseases, and makes up part of the OPDC with its work into Parkinson's, with the aim to understand the molecular mechanisms of these disorders and help develop new treatments. This video is narrated by Professor Richard Wade-Martins, with contributions from Charmaine Lang, Dayne Beccano-Kelly, Peter Kilfeather, Phillippa Carling, Gabriela Vilema Enriquez and former members of the team, Gabriele Corda, Rebecca Wallings and Marta Cherubini. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/inside-the-wade-martins-lab |
| Description | News story and video highlighting an OPDC study that has uncovered a new way to target and treat the leading genetic contributor to Parkinson's |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | News story featuring a research paper that has identified how the dysfunction of a key protein, LRRK2, causes the neurons affected in Parkinson's to lose their ability to effectively clear out cell components that have been damaged. This discovery has enabled the team to find a new way to target and correct this issue, paving the way for a potential new clinical treatment. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/opdc-study-uncovers-a-new-way-to-target-and-treat-the-leading-genetic-cont... |
| Description | News story featuring a new study on neurons grown from skin samples reveals key molecular changes in people with Parkinson's |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | News story highlighting a new research paper in Human Molecular Genetics: Cellular a-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/new-opdc-study-on-neurons-grown-from-skin-samples-reveals-key-molecular-ch... |
| Description | News story highlighting Dayne Beccano-Kelly, who shares his experience of being a black professional in academia & the wider story of race in research |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dayne Beccano-Kelly, an electrophysiologist and Career Development Fellow in the Department of Physiology, Anatomy and Genetics, and part of the Oxford Parkinson's Disease Centre (OPDC) spoke to Parkinson's Life about his experience as a black professional working in Parkinson's research. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.opdc.ox.ac.uk/opdc-researcher-shares-his-experience-of-being-a-black-professional-in-aca... |
| Description | News story highlighting a new paper to report genome-wide transcriptomic RNA-Seq profiling of stem cell-derived astrocytes from people with Parkinson's & healthy controls. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The news items highlighted a new research paper that was published to report genome-wide transcriptomic RNA-Seq profiling of stem cell-derived astrocytes from people with Parkinson's & healthy controls. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/new-opdc-research-into-the-role-of-astrocytes-in-parkinson-s-progression |
| Description | News story highlighting a new study which has shown that the key protein RE1 Silencing Transcription Factor (REST) regulates the health of those neurons critically affected in Parkinson's Disease. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A study led by University of Oxford researchers, Dr Brent Ryan and Dr Nora Bengoa-Vergniory has shown that the key protein RE1 Silencing Transcription Factor (REST) regulates the health of those neurons critically affected in Parkinson's Disease. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.opdc.ox.ac.uk/dopamine-neurons-need-a-rest-in-parkinson-s-disease |
| Description | News story highlighting a study that a novel assay termed the tau-proximity ligation assay is able to recognise Alzheimer's disease before current detection methods. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A study led by the Oxford Parkinson's Disease Centre's (OPDC) Dr Nora Bengoa-Vergniory has shown that a novel assay termed the tau-proximity ligation assay is able to recognise Alzheimer's disease before current detection methods. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.opdc.ox.ac.uk/tau-proximity-ligation-assay-reveals-extensive-previously-undetected-patho... |
| Description | News story promoting that Milena Cioroch is awarded Apprentice of the Month for March 2020 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Milena Cioroch, Research Assistant in the Wade-Martins Lab at the Oxford Parkinson's Disease Centre, was awarded Apprentice of the Month for March 2020 by her training provider Abingdon and Witney College. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.opdc.ox.ac.uk/milena-cioroch-is-awarded-apprentice-of-the-month-for-march-2020 |
| Description | News story promoting that a new study finds mutations in the gene LRRK2 affect normal cell function |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | A new story featured on our website about a new study from OPDC Career Development Fellow Natalie Connor-Robson who has investigated how mutations in the gene LRRK2, which are known to cause Parkinson's, effect normal cell function. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/opdc-study-finds-mutations-in-the-gene-lrrk2-affect-normal-cell-function |
| Description | News story to highlight OPDC Career Development Fellow Dr Dayne Beccano-Kelly has been selected by The World Parkinson Coalition (WPC) to be one of eight Science Ambassadors leading up to the 6th World Parkinson Congress |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | PDC Career Development Fellow Dr Dayne Beccano-Kelly has been selected by The World Parkinson Coalition (WPC) to be one of eight Science Ambassadors leading up to the 6th World Parkinson Congress in June 2022. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.opdc.ox.ac.uk/opdc-s-dayne-beccano-kelly-appointed-world-parkinson-coalition-science-amb... |
| Description | News story to highlight OPDC Researchers participating in fundraising for Parkinson's UK |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | On Sunday 26 April, members of the Wade-Martins Group from the Oxford Parkinson's Disease Centre threw themselves into a variety of imaginative challenges for the national 2.6 challenge campaign to raise vital funds for Parkinson's UK. The challenge required participants to dream up an activity based around the numbers 2.6 or 26 that suits their skills and complete it on Sunday 26 April - when the 40th London Marathon would have taken place. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dpag.ox.ac.uk/news/opdc-researchers-hit-target-for-parkinsons-uk-with-2-6-challenge |
| Description | News updates on the DPUK website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Developing news updates for the website and publishing press releases generated 6,599 page view during 2019 |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/news-and-features |
| Description | Nora Bengoa-Vergniory article on Celgene Fellowship |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Interviwe with Dr Nora Bengoa-Vergniory on her experience as a Celgene Fellow for the Oxford University Medical Sciences division website |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.medsci.ox.ac.uk/research/internal/funding-directory/oxford-celgene-fellowship/oxford-cel... |
| Description | November 2016, WISH Summit (Qatar) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | - |
| Year(s) Of Engagement Activity | 2016 |
| Description | Numerous social media posts to welcome new lab members |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Over the year, we have sent numerous social media post welcoming new lab members to the research team, and linking to their profiles on our website |
| Year(s) Of Engagement Activity | 2021 |
| Description | OLS/UKRI cross sector specialist workshop/committee for new national dementia initiative strategy for 2022 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Meeting with No.10 officials on UK Dementia landscape. |
| Year(s) Of Engagement Activity | 2021,2022 |
| Description | OPDC 11 July 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 11 July 2019, Austen Milnerwood, The Neuro, McGill University, gave a talk on 'The Quest for Neuroprotection in Parkinson's disease: reversing synaptic dysfunction'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Facebook Page |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | Creation of OPDC Facebook page. Used to update on OPDC activity. Focus on outreach events, but also includes news about publications etc. Also used boosted posts to promote OPDC open day. |
| Year(s) Of Engagement Activity | 2017,2018,2019 |
| URL | https://www.facebook.com/OxfordPDCentre/ |
| Description | OPDC Newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | In Septmeber 2019, the OPDC Autumn Newsletter was printed and published online. It included updates on:- our cohort studies from our cohort director Michele Hu, our work using smartphones to monitor Parkinson's progression. a key protein in Parkinson's which is showing promise for drug discovery understanding the genetics of Parkinson's the World Parkinson's Congress, Kyoto. The newsletter also includes a a poem by Maggie Lines and branch news from Parkinson's UK Milton Keynes. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/issue-10-autumn-newsletter-2019.pdf |
| Description | OPDC Newsletter Summer 2017 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | We have produced a 12 page newsletter with updates on our recent activities. This includes OPDC research news, outreach activities and news from members of the cohort and Parkinson's UK. The newsletter is posted to all cohort members and emailed to those on the news mailing list. It is also available online. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.opdc.ox.ac.uk/newsletters |
| Description | OPDC Open Day 2016 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | OPDC Open Day 2016 250 OPDC study Participants and Partners registered for event. Day of talks from Michele Hu, Fahd Baig, Claudio Ruffmann, Tom Barber and Richard Wade-Martins. Discussion of what participants would like from study. Talks filmed and podcasts added to website |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.opdc.ox.ac.uk/openday2016 |
| Description | OPDC Open Day 2017 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | We held an afternoon of talks and invited members of our cohort, their supprters, and members of the Thames Valley Parkinson's UK Excellence Network to attend. Around 200 people registered for the event and the feedback was largey positive. We have moved to a larger venue out of the city centre to allow us to offer parking. Talks were filmed and are available on our website and YouTube channel. Speakers at the event were Michele Hu, Mark Kelly, James Cantley, Tom Barber, Christine Lo, Sally Cowley and Richard Wade-Martins. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.opdc.ox.ac.uk/openday2017 |
| Description | OPDC Open Day talks online |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Study participants or study members |
| Results and Impact | A series of talks recorded at the 2018 OPDC Particpant's day are available to view on our YouTube channel and on our website. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.opdc.ox.ac.uk/videos |
| Description | OPDC Research Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | We held a research day to present an update on current Parkinson's research in the region and invited members of our SAB from overseas to present their work. This was attended by researchers from accross Oxford as well as members of the local Parkinon's UK group and interested study participants. We invited Hazel Stanyon, a study partiicpants who apoke about her experiences of how exercise has helped her Parkinson's symptoms and shared a poem. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.opdc.ox.ac.uk/research2018 |
| Description | OPDC Research Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | The OPDC Research Day is a one-day event with research talks from world leading Parkinson's researchers on topics including clinical studies, imaging, genetics, proteomics, neuronal cells and animal models. The 2017 OPDC Research Day was held in the Medical Sciences Teaching Centre, Oxford. There was a full day of talks and poster sessions on Parkinson's research. This one-day event included research talks by national and international keynote speakers and Oxford researchers on a range of Parkinson's work including clinical studies, imaging, genetics, proteomics, neuronal cell culture and animal models. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.opdc.ox.ac.uk/research2017 |
| Description | OPDC Seminar 11 February 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 11 February 2022, Louis-Eric Trudeau gave an OPDC Seminar talk, titled, 'Making sense of the exuberant axonal connectivity of dopamine neurones'. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://talks.ox.ac.uk/talks/id/df0f906f-bf3d-41ca-b7fb-3026912ce1bf/ |
| Description | OPDC Seminar 12 November 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 12 November 2019, Evrando Fei Fang, University of Oslo, gave a talk on 'NAD+ and Mitophagy in Brain Ageing and Neurodegenerative Disorders'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar 13 November |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 13 November, Jerome Baufreton, Laboratory of Synaptic and Cellular Dynamics of Neuronal Networks, The Neuroscience Institute at Bordeaux, gave a talk on the 'Synaptic alterations in the indirect-pathway of the basal ganglia in experimental Parkinsonism |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar 15 October |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 15 October, Paolo Calabresi, University of Perugia, Italy, gave a talk on the 'Striatal synaptic dysfunction in Parkinson's disease'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar 16 July 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 16 July 2019, Esther Sammler, University of Dundee gave a talk on 'Interrogating LRRK2 kinase pathway in human bio-samples in Parkinson's disease'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar 20 January 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 20 January 2022, Pietro De Camilli gave an OPDC Seminar talk, titled, 'Intracellular Membrane Lipid Dynamics and Neurodegenerative Diseases'. |
| Year(s) Of Engagement Activity | 2021,2022 |
| URL | https://talks.ox.ac.uk/talks/id/27284d4a-7121-4d63-9c39-fe40f59dd518/ |
| Description | OPDC Seminar 22 November 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 22 November 2021, Dr Michael Henderson gave an OPDC seminar talk titled, 'Modulators of pathology progression in neurodegenerative disease'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/c26bb54d-93e4-406a-80c1-43bcbf11b31e/ |
| Description | OPDC Seminar 26 January 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 26th January 2021, Dr Wilma van de Berg gave an OPDC emianr talk titled, ' Tales from the human brain: a multi scale approach to elucidate pathogenic mechanisms involved in Parkinson's'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.opdc.ox.ac.uk/seminars-events |
| Description | OPDC Seminar 28 October 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 28 October 2019, Ellen Sidransky, National Human Genome Research Institute, NIH, gave a talk on 'The magic in the web of it: How a rare disorder is helping to untangle the mysteries of Parkinson's disease'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar 8 February 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | On *th February 2021, Emmanouil Metzakopian gave an OPDC Seminar talk titled 'CRISPR Cas9 genetic screens to ameliorate cellular stress in neurodegeneration'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.opdc.ox.ac.uk/seminars-events |
| Description | OPDC Seminar 8 March 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr. Nicolas Tritsch (Neuroscience Institute and Marlene & Paulo Fresco Institute for Parkinson's & Movement Disorders, New York University, gave an online OPDC seminar talk titled, Modulation of striatal circuits by midbrain dopamine neurons |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/28ca76e2-e9fa-4ef1-a3c7-d23a9bf39852/ |
| Description | OPDC Seminar April 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 16 April 2019, Darren Moore, Center for Neurodegenerative Science, Van Andel Research Institute, gave a talk on the 'Pathway to Parkinson's Disease: A Tale of Two Genes'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar June 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 12 June 2019, Sonia Gandhi, UCL Queen Square Institute of Neurology, gave a a talk on 'The toxic consequences of protein aggregation in Parkinson's disease'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar May 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 14 May 2019, Mart Saarma, University of Helsinki, gave a talk on the 'Unconventional Endoplasmic Reticulum Located Trophic Factor for Parkinson's Disease'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar September 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 17 September 2019, Michael Coleman, Department of Clinical Neurosciences, University of Cambridge, gave a talk in the 'Mechanisms of axon degeneration in injury and disease'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC Seminar held on 18 May 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 18 May 2022, Dr Nicole Calakos (Dept. of Neurology, Duke University, School of Medicine), gave an OPDC seminar talk titled, A hidden regulator of neuromodulation and motor learning: Protein synthesis by the integrated stress response (ISR) |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://talks.ox.ac.uk/talks/id/d3183e00-517f-418f-be8c-3150129c7230/ |
| Description | OPDC Seminar held on 22 June 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 22 June 2021, Dr Olga Corti gave an OPDC seminar titled, Mitophagy dysfunction in autosomal recessive Parkinson's disease: is it the whole story? |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/02973f03-653d-41da-bedf-cfedb5e8b829/ |
| Description | OPDC Seminar held on 24 May 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 26 May 2022, Dr Kevin McFarthing (Research Advisor, Parkinson's UK Oxford Branch) gave an in person OPDC seminar talk titled, 'The drug development landscape in Parkinson's'. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://talks.ox.ac.uk/talks/id/11a186f0-d507-49db-8355-9f6aa08ebcae/ |
| Description | OPDC Seminar held on 25 January 2023 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 25 January 2023, Dr. Daniela Berg, (University Medical Center Schleswig-Holstein, Germany) gave an online OPDC seminar talk titled, 'Prodromal PD-definition and impact for clinical studies'. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://talks.ox.ac.uk/talks/id/88329935-b48d-4ff8-b8bf-e69f60fadc04/ |
| Description | OPDC Seminar held on 27 February 2023 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 27 February 2023, Professor Malú Gámez Tansey (University of Florida) will give an OPDC seminar talk - title tbc. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://talks.ox.ac.uk/talks/persons/id/3d3d9b0c-14b6-4ef5-9734-30c1a3e3d2b6 |
| Description | OPDC Seminar held on 27 June 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 27 June, Dr. Mark R. Cookson (Laboratory of Neurogenetics, National Institute on Aging (NIA)) gave an OPDC seminar talk titled, 'The role of LRRK2 in familial and sporadic Parkinson's disease. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://talks.ox.ac.uk/talks/id/c248cab1-6fb4-45ee-a14d-1e53d3eb1b2f/ |
| Description | OPDC Seminar held on 30 March 2023 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 30 March 2023, Professor Pascal Kaeser (Harvard Medical School) will give an OPDC online seminar talk titled, 'Mechanisms and Roles of Fast Dopamine Signaling'. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://talks.ox.ac.uk/talks/id/e623ef3c-aff1-4117-852e-93500d350276/ |
| Description | OPDC Seminar held on 31 October 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 31 October 2022, Suzanne Pfeffer, Ph.D. (Stanford University School of Medicine) gave an online OPDC seminar talk titled, 'LRRK2 kinase in Parkinson's disease: from single molecule to the brain'. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://talks.ox.ac.uk/talks/id/161e8a60-d515-4545-9ade-3f89b3413b00/ |
| Description | OPDC Seminar held on 6 July 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 6 July 2021, Dr Mark Howe gave an OPDC seminar talk titled, 'Sub-second Striatum Neuromodulatory Signaling on Multiple Spatial Scales During Learning and Action'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/da6b9878-7df5-47b2-98f3-0e1cb10ee3ac/ |
| Description | OPDC Seminar held on 6 July 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 6 July 2022, Dr Clemens Scherzer (Harvard Medical School) gave an online OPDC seminar talk titled, 'Cell circuits, progression genetics, and the quest to solve Parkinson's with precision medicine'. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://talks.ox.ac.uk/talks/id/308dacef-951d-4fbb-980f-af68c03dd0ed/ |
| Description | OPDC Seminar held on 7 December 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 7 December 2021, Dinos Meletis gave an OPDC seminar talk titled, 'Molecular and functional organization of the mouse striatum'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/9ab779f8-edc6-4043-adf2-e9a82a04aa5e/ |
| Description | OPDC YouTube channel |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Creation of OPDC YouTube channel to collate our podcasts etc. 32 subscribers, >2,860 views Feb 2016-Jan 2017. 2016 talks >1,450 views, 2016 OPDC highlights video >350 views, 2015 talks >1,000 views |
| Year(s) Of Engagement Activity | 2015,2016 |
| URL | http://www.youtube.com/channel/UCGzboizARwaAUFW5FjPmmZw |
| Description | OPDC newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | Issue 9 of the OPDC Newsletter was printed and published online. The newsletter give an important update on all our research activities. Our Winter 2018/19 newsletter included an update on our cohort studies, a new study to look at sleep in the home, and an update on our work using smartphones to monitor Parkinson's progression. Our statistician has been working to define new subsets of Parkinson's and our brain imaging research finds links between apathy and REM Sleep Behaviour Disorder (RBD). There is also news on how we have used skin cells donated by cohort members to derive dopamine neurons in our labs and used these to study how one common variant in genetics can increase the risk of sporadic Parkinson's. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/opdc2018-19-newsletter.pdf |
| Description | OPDC newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | In March 2022, the OPDC newsletter was circulated in hard copy and online. The Spring 2022 newsletter included: Updates from the discovery team on the UPP project, Introducing the Central Oxford Cohort Team, News for research participants, OPDC team update, Parkinson's UK walk, New laboratory facilities, Current OPDC research work and findings, Two major new Grants and Giving to OPDC |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dpag.ox.ac.uk/files/research/opdc-newsletter-march-2022 |
| Description | OPDC researchers welcome Parkinson's UK and the Oxford Branch committee |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | In March 2022, the Oxford Parkinson's Disease Centre (OPDC) hosted Caroline Rassell, Parkinson's UK Chief Executive; David Dexter, Associate Research Director; Trustee Board members, Gary Shaughnessy (Chair) and Sally Bromley; together with members of the Parkinson's UK Oxford Branch committee, for a visit to showcase the research being carried out in Oxford. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dpag.ox.ac.uk/opdc/news/latest/opdc-researchers-welcome-parkinson2019s-uk-and-the-oxford... |
| Description | OPDC seminar Feb 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 13 February Elisa Greggio, Department of Biology, University of Padova, gave a seminar talk on the 'Molecular pathways to Parkinson's disease: more than neurons?' |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC seminar March 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 27 March 2019, Kirsten Harvey, UCL School of Pharmacy, gave a talk on the 'LRRK2 Mediated Cellular Function from Vesicular Trafficking to Gene Expression'. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/_asset/file/2019-seminar-series.pdf |
| Description | OPDC welcomes Participants to Open Day |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | On September 10th, 2018 over 200 members of Discovery cohort came to the Jury's Inn, Oxford to hear about our latest research and share their views. We would like to thank all of the cohort members who came to the event from our centres across the country, and joined in the lively discussion session. Researchers from across OPDC's themes shared their work. These included talks on our work to develop a new test for Parkinson's, how we are using skin biopsy samples from our cohort to look for new potential therapies and new drugs trials on our horizon, our work to improve sleep studies, how we are working with other large studies of people with Parkinson's to better define Parkinson's and our work on dyskinesia. We also heard about a new survey to define top priorities for Parkinson's research and heard more about the brain donation process. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.opdc.ox.ac.uk/opdc-welcomes-participants-to-open-day |
| Description | Online Cohort 'site visits' - CaPS, PROTECT, ALSPAC |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Continuing the open dialogue between DPUK central office/management our platform's valuable cohorts - giving them updates on: the DPUK Data Portal; DPUK2 activities; data access management; any other business. This helps keep engagement for approval of data access requests for individual work or datathons. |
| Year(s) Of Engagement Activity | 2020,2021 |
| Description | Online OPDC Seminar 12 October 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 12 October 2021, Dr Sreeganga Chandra gave an OPDC Seminar talk titled. 'Synaptic Vesicle Endocytosis and Parkinson's disease'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/043b029a-b6e5-4f8a-bd85-1bff8906b38d/ |
| Description | Online OPDC Seminar 17 May 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 17 May 2021, Dr. Per Borghammer gave an OPDC seminar talk titled, 'Body-first & Brain-first Parkinson's disease - explaining motor asymmetry, non-motor subtypes, and dementia'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/055dec13-1a48-4068-94ee-ceb9b65ac2a5/ |
| Description | Online OPDC Seminar 19 April 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Policymakers/politicians |
| Results and Impact | On 19 APril 2021, Dr Anne Grünewald, Associate Professor at the University of Luxembourg gave an online OPDC seminar talk titled, 'Mitochondrial DNA at the interface between mitochondrial dysfunction and inflammation in Parkinson's disease'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/f8696cd5-aa1c-4e2c-ada5-a4c08976364b/ |
| Description | Online OPDC Seminar on 22 September 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 22 September 2021, David Rubinsztein gave an OPDC seminar talk, titled, 'Autophagy and neurodegeneration'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/e89c9fb6-1634-45f8-86c0-f43eb5fe22c8/ |
| Description | Online Short Course - ARUK and Futurelearn |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2019 |
| Description | Online presentation on DPUK at the Korean Brain Research Institute |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on DPUK at the Korean Brain Research Institute, over an online seminar. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.kbri.re.kr/new/pages_eng/main/ |
| Description | Oral Presentation - Dr D Street Early Careers Researchers Day ARUK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prediagnostic Frontotemporal Dementia - what can we learn from the UK Biobank? - Early Career Researchers Day, Alzheimer's Research UK Annual Conference |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation - University of Cambridge, Clinical Neuroscience Seminars Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | "Beyond proteinopathies, in vivo markers for inflammation and synaptic loss in frontotemporal lobar degeneration" - Clinical Neurosciences Seminars |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation @ ADPD Barcelona 20222- Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "In vivo PET imaging of inflammation as a prognostic tool in frontotemporal dementia" - ADPD conference (Barcelona, 03/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation @ Neuro2022: The CurePSP International Research Symposium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | PET imaging in PSP |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://live.classy.org/register/neuro2022/75abac00-afb9-41c4-834c-0e1e1b764c6d |
| Description | Oral Presentation @ Regional Meetinig (Norfolk & Suffolk Talk) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation titled "Update on Frontotemporal Dementia" given to audience of Consultants, Registrars and other health professions at a regional meeting for continuing professional development. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation @ UCL Neurosciences Society - Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | "Mechanisms of neurodegenerative diseases and their study through PET scans" - invited lecture at the UCL Neurosciences Society (London, UK, 01/12/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation ARUK Conference, UK - Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | "In vivo synaptic density PET in behavioural variant of frontotemporal dementia" - Alzheimer's Research UK conference (Brighton, UK - 03/2022) |
| Year(s) Of Engagement Activity | 2023 |
| Description | Oral Presentation at Cambridge Conversations - Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk title "The Dementia Journey - New advances, insights and possibilities" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation at International FRONTIER research conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | PET Imaging in PSP |
| Year(s) Of Engagement Activity | 2023 |
| Description | Oral Presentation at: "Association of Sri Lankan Neurologists, Annual Conference" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Understanding the Spectrum of Disease caused by FTLD" - talk title |
| Year(s) Of Engagement Activity | 2023 |
| Description | Oral Presentation on MEG Data Analysis @ BIOMAG2022 - Dr Amirhossein Jafarain |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Jafarain gave a technical talk in the flagship of MEG data analysis conferences BIOMAG2022. The Title of the oral presentation was : Neurochemistry-enriched dynamic causal models of magnetoencephalography, using magnetic resonance spectroscopy |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://biomag2020.org/programme/ |
| Description | Oral Presentation: AAIC Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Regional tau PET patterns predict prospective domain-specific cognitive decline in Alzheimer's Disease" - Alzheimer's Association International Conference (San Diego, US - 08/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation: Biophysical models of Dementia @ BIOMAG 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk title "Biophysical models of Dementia" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation: Cambridge Imaging Festival Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | "What's new in PET neuroimaging in Cambridge?" - Cambridge Imaging Festival (University of Cambridge, Cambridge, UK, 28/06/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation: Cambridge Methods Day (Dr M Malpetti) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Structural MRI vs. synaptic PET in dementia"- Cambridge Methods Day, MRC Cognition and Brain Sciences Unit (Cambridge, UK, 05/12/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation: Cambridge Neurosciences Symposium 2022 New Horizons - Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Inflammation: risks, prodrome and prediction of dementia" - Cambridge Neurosciences Symposium 2022: New Horizons (University of Cambridge, Cambridge, UK - 29/09/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation: International Society for FTD Dr Negin Holland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Title: 'Synaptic loss over time is related to worsening symptoms, in people with progressive supranuclear palsy and corticobasal syndrome.' |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation: International Society for Frontotemporal Dementia Congress - Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk title "PET imaging of synaptic health in syndromes associated with frontotemporal lobar degeneration" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation: Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2023 - Dr M Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Molecular imaging in Frontotemporal dementias" - Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2023 Mid-Winter Meeting (San Francisco, US, 28/01/2023) |
| Year(s) Of Engagement Activity | 2023 |
| Description | Oral Presentation: Translational neuropsychiatry @ BIOMAG 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk title "Translational neuropsychiatry" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral Presentation: UK PET Innovation Network Workshop - Dr M Malpetti |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | "PET imaging in dementia: novel approaches towards therapeutics" - UK PET Innovation Network Workshop (Rutherford Appleton Laboratory, Didcot, UK, 07/09/2022) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oral presentation at AI Symposium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | - AI for Social Good Symposium |
| Year(s) Of Engagement Activity | 2023 |
| Description | Organisation of training workshop for early career researchers of the DEMON network (International network for data science and AI applied to dementia) "Combining imaging data using machine learning" |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | The educational workshop 'Combining imaging data using machine learning' was held on 14-15 September 2021 and organised by the early career researchers and imaging working groups of the DEMON (International network for data science and AI applied to dementia) network (https://demondementia.com/). This two-day workshop provided theoretical learning and practical training for over 120 early career researchers on machine learning approaches to combine datasets (Day 1) and modalities (Day 2) in the context of dementia research. The event consisted of two talks each day, followed by practical tutorials (three on Day 1 and two on Day 2) led by skilled facilitators and experts of the field. The main goal of the workshop was to inform early career researchers with experience or interest in using imaging data about innovative machine learning approaches and algorithms that may be used to characterise the structure and function of the nervous system, identify meaningful patterns and support clinical decisions in dementia. The organising committee was also formed by early career researchers: Ludovica Griffanti (University of Oxford), Faeze Heidari (Iran University of Medical Sciences), Luiza Machado (Universidade Federal do Rio Grande do Sul), Maura Malpetti (University of Cambridge) and Henry Musto (Goldsmiths University). |
| Year(s) Of Engagement Activity | 2021 |
| Description | Organised and hosted Oxford talk with UCL's Dr Daniel Davis (PI of DELPHIC Cohort) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | John Gallacher invited Dr Daniel Davis (UCL Wellcome Trust Intermediate Clinical Fellow, Honorary Consultant in Geriatric Medicine and PI of the DELPHIC cohort) to present a seminar at the Department of Psychiatry in the University of Oxford. His primary interest is the relationship between delirium and/or acute illness and trajectories of cognitive decline in large population-representative studies, and his talk indeed covered lessons learnt from population studies when it comes to delirium and long-term cognitive outcomes. Sarah Bauermeister acted as chair of the session and fielded questions from the audience, including those from undergraduate students to eminent professors in the field. The talk highlighted the importance of cohort studies and their value in research to cognitive diseases to a well respected and well represented audience. A final question of the day highlighted DPUK's role in hosting DELPHIC data on the Data Portal, with Dr Davis agreeing as to the importance of the DPUK initiatives and mission to improve data accessibility and analysis from valuable cohort research. The day strengthened the ongoing relationship between senior management and the cohort, and also gave local DPUK team members (data curators, researchers etc) to learn more about this study's work and nuances. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://talks.ox.ac.uk/talks/id/0caf10ff-2347-423f-b24d-b859a4fcbb2c/ |
| Description | Organised talk by Cohort Lead at DPUK's host institution, University of Oxford |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Professor Marcus Richards, professor of Psychology in Epidemiology at UCL, senior researcher in NHSD cohort, and DPUK workpackage lead, delivered a talk at the University of Oxford's Department of Psychiatry. His talk was entitled 'Life course antecedents of cognitive reserve and dementia risk' The seminar space was full, with people standing in the back, indicating a keen interest in epidemiology, data science, AD and DPUK's work in facilitating progress in these areas. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Organised talk by a esteemed researcher at DPUK's host institution, University of Oxford |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Prof Carole DuFouil, Research Professor at the Bordeaux School of Public Health and PI of the MEMENTO cohort (a DPUK collaborating cohort), was invited to speak on 'Alzheimer's Disease biomarkers: a population perspective' at the Department of Psychiatry, University of Oxford. The seminar space was full, with people standing in the back, indicating a keen interest in epidemiology, data science, AD and DPUK's work in facilitating progress in these areas. Carole received several questions on the day as well as e-mail requests before and after the event. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Overview of Trusted Research Environment globally, Dementias Platform Australia, University of New South Wales |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Overview of Trusted Research Environment globally, Dementias Platform Australia, University of New South Wales, 08/11/22 |
| Year(s) Of Engagement Activity | 2022 |
| Description | OxDARE summer 2020 newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | I spoke about my work that was presented in the virtual ARUK Conference 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.oxdare.ox.ac.uk/_asset/file/issue-10-summer-2020.pdf |
| Description | Oxford Brain Day |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Spoke about the Deep and Frequent Phenotyping Study |
| Year(s) Of Engagement Activity | 2020 |
| Description | Oxford Dementia Research Day 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster: The MRC DPUK Data Portal: Bringing Researchers to Data: The Research Journey: Bauermeister, S. & Gallacher, J. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Oxford Drug Discovery Institute Research Symposium, Oxford UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | In September 2022, Professor Richard Wade-Martins gave a talk at the Oxford Drug Discovery Institute Research Symposium, Oxford UK |
| Year(s) Of Engagement Activity | 2022 |
| Description | Oxford Mail, 18th December 2020 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | https://www.oxfordmail.co.uk/news/18952877.brain-study-alzheimers-seeking-volunteers-oxford/ |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.oxfordmail.co.uk/news/18952877.brain-study-alzheimers-seeking-volunteers-oxford/ |
| Description | Oxford PD UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | I spoke at a meeting of the Oxford Parkinson's UK branch |
| Year(s) Of Engagement Activity | 2017 |
| Description | Oxford PD UK Carol Service and walk 2016 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Attended and supported Parkinson's UK Oxford Carol service and sponsored walk 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Oxford Parkinson's Disease Centre pays tribute to one of its loyal fundraisers |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Researchers from the Oxford Parkinson's Disease Centre (OPDC) paid tribute to Bobbie Coelho, one of the OPDC's long term fundraisers who has decided to take a step back from active fundraising activities. A video message was created from OPDC researchers thanking her for all the amazing work she has done towards funding Parkinson's research over the years. Together with a bouquet of flowers, they also gave her an engraved glass OPDC honorary award which was presented to her 'in recognition of outstanding fundraising to support research into Parkinson's'. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.opdc.ox.ac.uk/oxford-parkinson-s-disease-centre-pays-tribute-to-one-of-its-loyal-fundrai... |
| Description | Oxford Parkinson's Research Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | On Tuesday 29th November 2022, Professor Richard Wade-Martins and Professor Michele Hu from the Oxford Parkinson's Disease Centre (OPDC) hosted the Oxford Parkinson's Research Day at the Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford. Professor Irene Tracey, Vice-Chancellor Elect of the University of Oxford, Warden of Merton College and Professor of Anaesthetic Neuroscience, opened the days' proceedings. The programme was split across four sessions covering a wide range of translational work into Parkinson's: "Clinical Research into Parkinson's", "Translational models of Parkinson's", "Molecular Mechanisms and related biomarkers", and "Cellular models and target discovery" describing work across the University and from our collaborators. There were three invited keynote speakers:- Professor Masud Husain, University of Oxford. Masud Husain is Professor of Neurology & Cognitive Neuroscience at the University of Oxford. He leads the Neurological Conditions theme of the NIHR Oxford Biomedical Research Centre and is Editor-in-Chief of the publication, Brain. Together with Cornelia van Duijn, he leads Dementia Research Oxford. Professor Husain's presentation was titled, "When the spark goes out: the neurology of motivation and apathy". Professor Miratul Muqit, University of Dundee. Miratul Muqit is Professor (Clinical) MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee. His laboratory studies the protein kinase, PTEN-induced kinase 1 (PINK1) in which loss of function mutations cause Parkinson's disease. Professor Muqit presented, "Decoding Mitochondrial Damage Response Pathways linked to Parkinson's disease". Professor Sonia Gandhi, UCL. Sonia Gandhi is Professor of Neurology, Clinical and Movement Neurosciences at Queen Square Institute of Neurology, University College London. Professor Gandhi's laboratory works on the cellular and molecular biology of Parkinson's and her talk title was, "Thinking big to see small: from nanoscale to mesoscale resolution in Parkinson's". In addition to the talks, there were 37 poster presentations on display throughout the day. The event closed with Dr Kevin McFarthing, Research Advisor, Parkinson's UK Oxford Branch, presenting the best poster award voted for by all attendees. The prize awarded for the best poster was won by DPhil student Victor (Shijun) Yan, from the Molecular Neurodegeneration Research Group, University of Oxford, for his poster titled, 'a-synuclein in L1CAM-Positive Serum Extracellular Vesicles as a predictive biomarker for Parkinson's disease pathology'. Selected talks included Charmaine Lang, Peter Kilfeather, Sally Cowly, Michael Lawton, Becky Carlyle, George Tofaris, Laura Parkkinen, Katherine Brimblecombe, Ira Milosovic |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.dpag.ox.ac.uk/opdc/oxford-parkinson2019s-disease-centre-host-the-2022-oxford-parkinson20... |
| Description | Oxford Science Festival Information Stand |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Oxford Science Festival, June 2016 (Clare MacKay manned a stand) |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.oxfordshiresciencefestival.com/ |
| Description | Oxford Sleep Study #OxfordAI video |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Sleep study on wearable technology chosen by Oxford University team for a feature video as part of their OxfordAI series. Coverage on Oxford University website, twitter and facebook feeds. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.facebook.com/the.university.of.oxford/videos/2136127846704050/ |
| Description | Oxford Sparks'animation about the role of microglia in neurodegeneration |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Postdoc Hazel Roberts won Oxford Sparks' competition to have an animation made about the role of microglia in neurodegeneration. Title: Discovering life-changing dementia treatments. Your beautiful, complex brain is a network of microscopic cells that connect together to form your thoughts and personality, and control your body. The network is fragile and requires constant upkeep, like a garden. The brain has its own gardeners, specialised cells called microglia. In this animation we look at how researchers at the University of Oxford are developing drug treatments for Alzheimer's disease, by harnessing the power of the brain's microglia. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.oxfordsparks.ox.ac.uk/content/discovering-life-changing-dementia-treatments |
| Description | Oxford University article on HDAC4 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Article on front page on Oxford University website based on HDAC4 pressrelease from parkinson's UK |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.ox.ac.uk/news/2018-11-30-experimental-cancer-drug-shows-promise-parkinson%E2%80%99s |
| Description | PPE - Cambridge university Hospitals Trust members |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | An evening event for the members of the Trust (patients, and local public) to discuss advances in dementia research and care, including the insights from new technologies |
| Year(s) Of Engagement Activity | 2019 |
| Description | PSP Association "Ask the Doctor" with Negin Holland |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | 'Ask the Dr' event for newly diagnosed patients with PSP and CBD. In this 2 hour long session, Dr Holland spoke with newly diagnosed patients and their carers about what PSP/CBD is, current treatments, and management. A question-and-answer session was also held for this group. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Panel discussion: ISTAART careers in science |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | Panel to review DPUK Great Minds in London - proving feedback on risk/consent of participating in dementia research |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Patient and Public Involvement working group for DPUK Great Minds, a clinical studies register. Discussed and got views on consent and risk data. Feedback has shaped how we provide information on a public website, and clarified our privacy policies. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.greatmindsfordementia.uk/ |
| Description | Parker, AAIC London (2017) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Thomas Parker submitted an abstract and gave a presentation at AAIC London (2017) entitled, "Brain volume, cerebral ß-amyloid deposition, and ageing: a study of over 200 individuals born in the same week in 1946". This presentation sparked questions and discussion amongst attendees of the conference. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Parkinson's Documentary - Kent University |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Richard Wade-Martins interview with Isabelle Miller, a journalist at the University of Kent for a documentary about young people who have Parkinson's (20s-30s). To be produced Mar 2018 ------ A bit more about the documentary: It will be a 15-30 minute long-from television documentary. A lot of people forget that it occurs in young people as well as older people, although less common. I want to educate people on how individual it really is, as well as raise awareness, therefore gaining more support. I also want people to see how a young person adapts their life to the condition. Having Parkinson's at a working age is a whole different challenge compared to those who have it later in life. Some have to stop working, some are determined to continue and be a part of the ever-developing research. I want to show people that, yes, it is difficult to live with Parkinson's, and research into YOPD needs to be funded further, however, I also want to show how people make life their own. It would be an insight into both the struggles and normalities people with Parkinson's face. This is a topic which has light and shade for viewers and will serve a great purpose in informing those who need the information. |
| Year(s) Of Engagement Activity | 2017,2018 |
| Description | Parkinson's Life online article on HDAC4 press release |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Article on research paper based on press relelase from Parkinson's UK |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://parkinsonslife.eu/repurposed-cancer-drug-parkinsons/ |
| Description | Parkinson's UK Blog Post on HDAC paper |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Blog by Claire bale on Parkinson's UK Blog Using brain cells grown from skin to find new potential drugs Researchers in Oxford are using pioneering stem cell techniques to understand the earliest problems that occur inside brain cells in Parkinson's - and hunt down new drugs that can tackle them. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://medium.com/parkinsons-uk/using-brain-cells-grown-from-skin-to-find-new-potential-drugs-78f56... |
| Description | Parkinson's UK Oxford Walk |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | On 22 September, Professor Richard Wade-Martins & Dr Laura Parkinnen took part in the Parkinson's UK Oxford Walk. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Parkinson's Walk 2017 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Supporters |
| Results and Impact | Members of OPDC took part in the Oxford Parkinson's Walk. Melanie Witt and Jane Rumbold manned an information stand with literature about our work and sign up sheets for infomration about participating in research. Taking part were Michele Hu, Richard Wade-Martins, Sally Cowley, Paul Bolam, Amandine Louvel, Tom Barber, Ludovica Griffanti, Marie Crabbe, ChristineLo, Johannes Klein, Jane Rumbold, Charmaine Lang and Rebecca Wallings. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.opdc.ox.ac.uk/opdc-joins-parkinson-s-uk-2017-oxford-walk |
| Description | Parkinson's public awareness talk at Green Templeton College |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | On 11 September 2019, Professor Wade-Martins gave a public awareness talk about Parkinson's Disease at Green Templeton College |
| Year(s) Of Engagement Activity | 2019 |
| Description | Participant at the International Cohorts Summit |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | The International 100K Cohort Consortium (IHCC) was established in 2018 at the request of the leaders of the Heads of International Research Organizations (HIROs) through a collaboration between the Global Genomic Medicine Collaborative (G2MC) and the Global Alliance for Genomics and Health (GA4GH). John was invited to contribute alongside the PIs of the most influential cohorts and their funders internationally to discuss: ? Improve prospects for interoperability and compatibility of instruments, data formats, phenotypic and clinical measures, etc. ? Promote data sharing and open access policies ? Broaden international cooperation through existing tools and resources ? Explore the feasibility of a "digital" platform, or web-based, evolving registry of large-scale cohorts, in searchable format ? Examine the potential for a collaborative sequencing (and other -omics?) strategy ? Consider strategies for translating findings for health impact ? Advance a collective vision: where do we want to be in ten years? |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://ihcc.g2mc.org/ |
| Description | Participation and presentation in UK DRI Big Data Workshop, supported by ARUK and AlzSoc |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Context Dementia represents one of the greatest health challenges of our time, with still no way to prevent, treat or slow its progression. Dementia researchers around the world are constantly generating large, heterogenous datasets, ranging from -omics, imaging to clinical data. Integrating these datasets and maximising the use of the data will enable research on a scale not previously possible, leading to transformational advances in dementia. The UK DRI would like to reach out to specialists in applying data science in health and biomedical fields to discuss (1) what we can achieve together, (2) how the UK DRI can benefit from the substantial assets and initiatives already in the UK and (3) how we can bridge findings from basic science research with clinical information. Presentations and discussions will address key questions such as · How to robustly, efficiently and securely link genomic data to cellular/functional data to detailed clinical information (such as neuroimaging, electronic health records)? · How to harness UK DRI's strength on preclinical-phase research to complement clinical studies? · Can we make computational models for the diseases? What would be needed to get there? · How to apply data science to neurodegeneration research in a translational context (e.g. early diagnosis, disease progression, novel biomarker/target discovery & precision medicine)? Anticipated outcome The objectives of this workshop are to · learn from experts in applying data science to health/biomedical research problems; · identify opportunities for big data analytics and computational research in neurodegeneration; · explore ways to connect findings from basic science research to real-world clinical data; · stimulate conversation with UK DRI researchers who produce and/or analyse large datasets; · foster strategic collaborations and/or partnerships. Dr Sarah Bauermeister (Senior Data & Science Manager, Dementias Platform UK). Dementias Platform UK (DPUK): Data Access for a Digital Age. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Participation in an activity, workshop or similar - Poster presentation at CTAD conference, Barcelona 24-27th October 2018: Child adversity |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation: Using the power of Dementias Platform UK (DPUK) cohorts to investigate the longitudinal effects of childhood adversity on adult cognition and health outcomes: Implications for cognitive change & dementia outcomes. Interest and discussion in our research and further work which will involve further cohorts and a publication. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.ctad-alzheimer.com/ |
| Description | Personal? to whom? Careers, custodianship and control in biomedical big-data |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Atkinson, S. 'Personal? to whom? Careers, custodianship and control in biomedical big-data'. Paper Presentation, BSA Medical Sociology Group Annual Conference 2016, Aston University, Birmingham, UK. Audience: Sociology of health, social studies of science and technology and social studies of bioinformatics |
| Year(s) Of Engagement Activity | 2016 |
| Description | Pete Magill welcomes Lord O'Shaughnessy, Parliamentary Under-Secretary of State for Health to OPDC & MRC BDNU |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The Medical Research Council Brain Network Dynamics Unit at the University of Oxford recently welcomed Lord James O'Shaughnessy, Parliamentary Under-Secretary of State for Health, for a site visit organised as part of The Royal Society's Pairing Scheme that OPDC theme 3 co-lead Professor Pete Magill is taking part in. The visit began with Unit Group Leaders Peter Brown, Peter Magill and Tim Denison highlighting why, how and where the Unit undertakes its cross-disciplinary research incorporating experimental neuroscience, clinical studies and bioengineering. This prompted some insightful discussion on the Unit's contribution to the UK's research and innovation landscape, as well as its alignment with government policy and strategy. Lord O'Shaughnessy then toured Unit facilities, and met with some of the Unit's early-career scientists who showcased the concepts and technologies underpinning their respective experiments. After lunch, Lord O'Shaughnessy visited Unit research collaborators at the Oxford Parkinson's Disease Centre and the ARUK Oxford Drug Discovery Institute. Peter Magill commented, "Lord O'Shaughnessy's visit was an invaluable opportunity for us to engage and to be engaged. The mutual exchange of knowledge was both invigorating and enlightening. I can highly recommend the Pairing Scheme to other scientists and policymakers." |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.opdc.ox.ac.uk/pete-magill-welcomes-lord-o-shaughnessy |
| Description | Pharma partnerships under CDA |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | A series of six pharma partnership meetings related to PSP and FTD novel therapeutics, under CDA/NDA Scoping the needs and opportunity, reviewing candidate product preclinical data, and developing better trial design, |
| Year(s) Of Engagement Activity | 2018 |
| Description | Physics of Life/Rosetrees Interdisciplinary Workshop on neurodegenerative diseases of the brain - February 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Physics of Life/Rosetrees Interdisciplinary Workshop on neurodegenerative diseases of the brain - February 2021 |
| Year(s) Of Engagement Activity | 2020 |
| Description | Plenary Speaker at Clinical Trials in Alzheimer's Disease (CTAD) conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Plenary Speaker at European Academy of Neurology on Imaging Trials and Dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Plenary Speaker at the Alzheimer's Association International Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The plenary speech described our scientific advances in gene discovery and AD risk prediction. This reached an audience of several thousand researchers, clinicians, families, policy makers and funders in the dementia area. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Plenary speaker: Cypriot Neurological Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2015 |
| Description | Plenary speaker: The neurology of ageing, ABN Annual Meeting, Brighton |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Population data and modelling: dementia as exemplar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A talk was given at the Cumberland initiative Festival of Evidence 5th of Oct 2016. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Poster - Rostock Retreat on Causality, Max Planck Institute, Rostock, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | To present research outcomes and to get feedback from other researchers |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.rostock-retreat.org/2018/ |
| Description | Poster at AAIC Conference July 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Emily Baker, PhD Student (Supervisor - Prof Valentina Escott-Price) Poster at AAIC Conference - July 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | Poster at ASHG Conference - October 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Emily Baker, PhD Student (Supervisor - Prof Valentina Escott-Price) Poster at ASHG Conference - October 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | Poster at Advances in Neurodegenerative Disease Research and Therapy/New Frontiers in Neuroinflammation Keystone Conference, Colorado USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Nora Bengoa-Vergniory poster "Tau-proximity ligation assay detects pathology ahead of tau neurofibrillary tangles in Alzheimer's disease" As the world population ages, neurodegenerative diseases are becoming the new epidemic in both developed and developing countries. Progress made in human genetics has revealed increasingly more disease-associated genes for Alzheimer's disease (AD), Parkinson's disease (PD), Frontotemoral dementia (FTD), amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders. These discoveries have linked neurodegenerative diseases with several common key biological processes that have so far been under-studied, including RNA metabolism, protein trafficking and innate immune responses. By focusing on these emerging areas in neurodegenerative disease research, this conference seeks to challenge the current research paradigms and to inspire in-depth discussion and exploration. The program assembles leaders from various fields to facilitate interactions between groups using diverse approaches, by providing a platform to cross-fertilize ideas and to encourage new collaborations that could lead to novel mechanisms and therapeutic targets against neurodegenerative diseases. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.keystonesymposia.org/18Z3 |
| Description | Poster at the Alzheimer's Research UK Conference March 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a poster on the associations of adverse life experiences and later life brain structure in 10,248 UK Biobank participants (Gheorghe, A. D., Bauermeister, S., Gallacher, J.) |
| Year(s) Of Engagement Activity | 2019 |
| Description | Poster by Dr Ellen Backhouse on behalf of the R4VaD study team. 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)', Glasgow, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster by Dr Ellen Backhouse on behalf of the R4VaD study team. 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)'. Organisation for Psychological Research into Stroke (OPSYRIS) meeting, Glasgow, 5th October 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Poster by Dr Ellen Backhouse on behalf of the R4VaD study team. 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)', Milan, Italy |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster by Dr Ellen Backhouse on behalf of the R4VaD study team. 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)'. European Stroke Organisation Conference 23rd May 2019, Milan |
| Year(s) Of Engagement Activity | 2019 |
| Description | Poster presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation to basic science and clinical researchers, next-generation investigators, clinicians and the care research community to share research discoveries that'll lead to methods of prevention and treatment and improvements in the diagnosis of Alzheimer's disease. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Poster presentation at CTAD conference, Barcelona 24-27th October 2018: Psychometric methodologies |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentaton of research work entitled: Psychometric methodologies to increase scale-reliability in dementia-focused epidemiology: Outcomes from the European Prevention of Alzheimer's Disease Study & UK Biobank. This work will be published in a peer reviewed journal at a later date. This work has gained great interest from the epidemiological community and further work in this field is planned as well as a grant application. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.ctad-alzheimer.com/ |
| Description | Poster presentation at DPUK Annual Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Outline presentation of work package 2 of DPUK, the informatics stream, at the time focusing on the build and purpose of the DPUK Data Portal. The poster featured a description of the envisaged tools, data management and planned activity for the coming year. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Poster presentation at OHBM conference - June 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation of the poster entitled: "Harmonising measures of white matter hyperintensities across sites and studies: impact of training and manual rating in FSL-BIANCA", which promoted discussion and feedback from colleagues and international researchers. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Poster presentation: "Dementias Platform UK Cross-Cohort Ontology: Facilitating Multi-Cohort Analysis" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation of a poster on the DPUK C-Surv curation techniques and ontologies at the Department of Psychiatry away day based in Oxford. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Poster presentations at the Dementia Research Day hosted by the ARUK Thames Valley Network |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 1st July 2022, members of the Wade-Martins ab presented posters at the 2022 Dementia Research Day hosed by the ARUK Thames Valley network. They included Tara Diviney, Jack Connor, Naroa Ibarra Aizpurua, Remya Nair, Kaitlyn Cramb, Ajantha Abey, Elena Britti, and Sarah Franks. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Poster presentations at the Oxford Parkinson's Research Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 29th November 2022, members of the Wade-Martins ab presented posters at the Oxford Parkinson's Research Day. They included Naroa Ibarra Aizpurua, Mahmoud Bassal, Elena Britti, Sarah Franks, Quyen Do, Ajantha Abey, Helle Begetofte, Tara Diviney, Remya Nair, William McGuinness, Rachel Heon Roberts, Kaitlyn Cramb, Maria Claudia Caiazza, Elliot Mock, Peter Kilfeather and Hugo Fernandes. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Power of Cohorts, Dementias Platform UK Annual meeting, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2018 |
| Description | Predicting incident dementia from cognitive test performance in UK Biobank. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Calvin C, et al. (2018). Predicting incident dementia from cognitive test performance in UK Biobank. Poster presentation at Alzheimer's Research UK, QEII, London on 20-21 March 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Preliminary psychometric results from the enhanced UK Biobank cognitive test battery: Dementias Platform UK Cognitive Assessment |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation at Dementias Platform UK Annual Conference |
| Year(s) Of Engagement Activity | 2017,2018 |
| Description | Presentation at Database Resources for Large-Scale and Complex Data workshop, Engineers' House, Bristol, 21st June 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chris Orton presented on the DPUK use case of UKSeRP and the enhancement of cohort data and research that this brings to the epidemiological and general scientific community in the sphere of Dementia. The presentation detailed the infrastructure supporting advancement in multi-modal data use and how to harness disparate data from eclectic and valuable sources across the world within a centralised management and access system, whilst allowing data providers to retain governance of their data. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation at the British Pharmacological Society Annual Conference, Online meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | In October 2020, Prof. Richard Wade-Martins gave a presentation at the British Pharmacological Society Annual Conference. Online meeting |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.bps.ac.uk/news-events/news |
| Description | Presentation at the conference; Grand Challenges in Parkinson's Disease, Van Andel Institute, Grand Rapids, MI |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In October 2021, Prof. Ricahrd Wade-Martins will be giving a presentation at the conference; Grand Challenges in Parkinson's Disease, Van Andel Institute, Grand Rapids, MI |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://grandchallengesinpd.org/ |
| Description | Presentation on Ageing Research for A-Level students at the UNIQ Summer School |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Presentation on Ageing Research for A-Level students at the UNIQ Summer School - https://www.psych.ox.ac.uk/team/naiara-demnitz |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.uniq.ox.ac.uk/ |
| Description | Presentation on DPUK as a use case of UKSeRP at the Administrative Data Research Network Conference, Royal Surgeon's Hall, Edinburgh, 1-2 June 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chris Orton, Data Project Manager for DPUK at Swansea University, presented on DPUK as a use case of UK Secure eResearch Platform at the ADRN Conference in Edinburgh on Friday 2nd June 2017. The presentation outlined the complex instance of UKSeRP that DPUK uses to host its infrastructure, namely the DPUK Data Portal, and also showed how this links to other national research organisations who are also making use of UKSeRP. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation on DPUK at MRC Pathfinder Workshop (Jan 2019) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | John was asked to give a short presentation (10 min) on the Dementias Platform UK at the MRC's 'Future development of a UK mental health research platform' meeting - sharing his experience and learning from establishing DPUK. In particular, his presentation addressed key information governance challenges, barriers and solutions, which was explored further in the discussion session which followed. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Presentation on dementia at Oxford Institute of Population Ageing (May 2019) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | The Institute of Population Ageing is a multi-disciplinary research institute focusing on the implications of demographic change. Their Trinity Term seminar series for 2019 focused on qualitative and quantitative methods for big data. John was asked to present his research at this seminar series in particular on ageing and dementia. It was a 45 minute talk followed by a 45 minute session for questions and discussions, allowing for increased engagement of DPUK's aims and methods to a new audience. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.ox.ac.uk/event/ageing-and-dementia-use-cognitive-and-psychological-assessment |
| Description | Presentation poster session at ADPD in Barcelona in March |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Maria Claudia Caiazza will be presenting her data in a poster session at the AD/PD conference in Barcelona between 15-20th March. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://adpd.kenes.com/ |
| Description | Presentation to MRC Council - Centre for the Improvement of Population Health through E-records Research (CIPHER) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Presentation to MRC Council on the success of the Farr CIPHER centre and its impact through science and public engagement, including the development of data sharing research platforms that underpin a number of major research initiatives, including DPUK and MQ Adolescent Mental Health Platform |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation to the general public on the DRI program at the DRI launch in Cardiff |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | I have presented on my DRI program "Bioinformatics and Functional genomics" to patients, their families, journalists and other invited guests from the general public at the DRI launch in Cardiff, October 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Presented a poster titled, 'TPC2 Expression and Function in Models of Parkinson's disease' at the Oxford Neuroscience Symposium |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | In March 2023, Johanna Hoffman presented a poster titled, 'TPC2 Expression and Function in Models of Parkinson's disease' at the Oxford Neuroscience Symposium. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.neuroscience.ox.ac.uk/about/oxford-neuroscience-symposium |
| Description | Presented a poster titled, 'TPC2 Expression and Function in Models of Parkinson's disease' at the Parkinson's Disease ECR UKDRI Manchester conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | In March 2023, Johanna Hoffman presented a poster titled, 'TPC2 Expression and Function in Models of Parkinson's disease' at the first in-person Parkinson's disease Early Career Researcher (ECR) meeting at the Core Technology Facility, University of Manchester. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presenter for UKRI Industrial Strategy workshop - ISCF Wave 3: Early Detection of Disease meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | a |
| Year(s) Of Engagement Activity | 2018 |
| Description | Press release New Therapeutics in Alzheimer's disease. |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | This press release targeted Oxford media in order to recruit volunteers to the Oxford study site. The Oxford Times and Oxford Mail carried the article and link to the recruitment page of the website, which had 254 pageviews and 26 expressions of interest in volunteering |
| Year(s) Of Engagement Activity | 2020 |
| Description | Press release about the Deep and Frequent Phenotyping project in Oxford |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The press release was sent to local media to drive volunteer recruitment to the DFP study. Vanessa Raymont was interviewed by JAck FM and BBC Radio Oxford and DFP pages received 1145 page views |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dementiasplatform.uk/our-impact/experimental-medicine/deep-and-frequent-phenotyping-stud... |
| Description | Primary School Tours of FMRIB Scanner |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Primary schools invited onto tours of the Oxford Centre for Functional MRI of the Brain (FMRIB). |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.oum.ox.ac.uk/braindiaries/ |
| Description | Prof Joanna Wardlaw expertise feature in British Heart Foundation press release "Stroke survivors twice as likely to be living with dementia " (5th March 2020) |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | British Heart Foundation press release ""Stroke survivors twice as likely to be living with dementia"- vascular dementia campaign, (5th March 2020) featuring expertise quote of Professor Joanna Wardlaw.. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://app.researchfish.com/portfolio/0/dissemination-to-non-academic-audiences?action=add&zone=por... |
| Description | Prof Joanna Wardlaw feature in "Vascular dementia: investigating cognitive impairment with 2,000 stroke survivors". |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Joanna Wardlaw feature in "Vascular dementia: investigating cognitive impairment with 2,000 stroke survivors". |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dementiasplatform.uk/news-and-blogs/blog/vascular-dementia-investigating-cognitive-impai... |
| Description | Prof Joanna Wardlaw feature in Health Matters magazine |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A feature in Health Matters magazine, Winter 2018-2019 issue, P 24-25. Wardlaw, JM. "MRI scans of the brain". |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw lecture "Brain Health: a small matter of the blood vessels" in Edinburgh, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Edinburgh Neuroscience Public Christmas Lecture 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "Brain Health: a small matter of the blood vessels" in Edinburgh, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Brain Health: a small matter of the blood vessels" at the Edinburgh Neuroscience Public Christmas Lecture 2018, 13th December 2018, Edinburgh, UK. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "Cerebral small vessel disease is a relapsing and remitting neurodegenerative disorder" in Birmingham, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Cerebral small vessel disease is a relapsing and remitting neurodegenerative disorder" on the 4th Oct 2019, MRC UK Dementia Research Institute Annual Scientific Meeting (Connectome), in Birmingham, UK |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk "Cerebral small vessel disease: novel targets for prevention" in Berlin, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave a talk on "Cerebral small vessel disease: novel targets for prevention" at the Dementia Prevention by Stroke Prevention' World Health Summit Satellite Symposium, 13th October 2018, Berlin, Germany |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies" at The University of Vermont |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave a talk on "Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies", at the The University of Vermont, 22nd October 2018, Burlington, Vermont, USA. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "Mapping vascular cognitive impairment: from early life to post-stroke dementia" in Telford, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave a talk on "Mapping vascular cognitive impairment: from early life to post-stroke dementia" at the 13th UK Stroke Forum Conference in Telford, UK on December 6, 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "Small Vessel Disease - LACI2 and R4VaD" NIHR Clinical Research Network West Midlands Stroke Specialty Open Meeting, 21st February 2020, Birmingham, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Small Vessel Disease - LACI2 and R4VaD" NIHR Clinical Research Network West Midlands Stroke Specialty Open Meeting, 21st February 2020, Birmingham, UK. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Prof Joanna Wardlaw talk "Vascular contributions to dementia" Imperial College Neuroscience and Dementia Research Institute Brain Meeting, January 7th 2021, London (virtual) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Vascular contributions to dementia" Imperial College Neuroscience and Dementia Research Institute Brain Meeting, January 7th 2021, London (virtual) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Prof Joanna Wardlaw talk "Vascular features on MRI in dementia - clinical implications and interpretation" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave a talk on "Vascular features on MRI in dementia - clinical implications and interpretation" at the 3rd UK Dementia MRI conference, 6 July 2018, Cambridge, UK. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "What makes a good paper and how to prepare it? Suggestions based on my person experience",Beijing, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "What makes a good paper and how to prepare it? Suggestions based on my person experience", at the Tiantan International Stroke Conference 2019, 28 June 2019, Beijing, China |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk "Where next for stroke research?" in Edinburgh, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Where next for stroke research?"at the 6th Edinburgh Stroke Winter School, 19th February 2019, Edinburgh, UK. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk 'New insights into clinical features of SVD' 20th Congress of the Chinese Cerebrovascular Diseases (CCCD2020) Chinese Stroke Society, 4 November 2020(virtua!) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk 'New insights into clinical features of SVD' 20th Congress of the Chinese Cerebrovascular Diseases (CCCD2020) Chinese Stroke Society, 4 November 2020(virtua!) |
| Year(s) Of Engagement Activity | 2020 |
| Description | Prof Joanna Wardlaw talk 'Why is one small blood vessel such a giant problem for mankind?', 2nd Lenstra Lecture, Lugano, Switzerland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk 'Why is one small blood vessel such a giant problem for mankind?' at the 2nd Lenstra Lecture 2019, Philantrhopic Endowed Lecture, Swiss Italian Centre for Neuroscience, in Lugano, Switzerland, 1 October 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Ricahrd Wade-Martin gave a talk at CRISPR in Drug Discovery, ELRIG Meeting, Babraham Institute, Cambridge |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 2nd March, Prof Richard Wade-Martins will give a talk titled, iPSC models of Parkinson's: from disease mechanisms to target discovery |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.elrig.org/portfolio/crispr-in-drug-discovery-2022/ |
| Description | Prof Richard Wade-Martins gave a seminar talk at the Dementia Research Oxford Seminars series |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 25 November 2021, Prof Richard Wade-Martins gave a seminar talk titled, 'Understanding tau and Abeta biology in health and disease'. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://talks.ox.ac.uk/talks/id/a2bcdeb9-f2f2-477b-a327-6bd0a6de0545/ |
| Description | Professor Joanna Wardlaw - Brain Healthy series, a collection of articles in the BMJ launched at the Chinese Stroke Association annual conference, 10 October 2020, Beijing, China |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Joanna Wardlaw- Brain Healthy series, a collection of articles in the BMJ launched at the Chinese Stroke Association annual conference, 10 October 2020, Beijing, China. The event reached the audience over 160,000 people. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Professor Joanna Wardlaw feature in BHF press release titled "Trial resumes to prevent dementia after a stroke", 3 December 2020 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Joanna Wardlaw feature in BHF press release titled "Trial resumes to prevent dementia after a stroke", 3 December 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.bhf.org.uk/search?keyword=Trial+resumes+to+prevent+dementia+after+a+stroke&run=1 |
| Description | Professor Joanna Wardlaw feature in The Scotsman press release Edinburgh University study re-launched into stroke treatment to prevent dementia, 3rd December 2020 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Joanna Wardlaw feature in The Scotsman press release Edinburgh University study re-launched into stroke treatment to prevent dementia, 3rd December 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.scotsman.com/health/edinburgh-university-study-re-launched-stroke-treatment-prevent-deme... |
| Description | Professor Joanna Wardlaw talk "Where next for stroke research?" 7th ESO Edinburgh Stroke Research Workshop, 26th February 2020, Edinburgh, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Joanna Wardlaw talk "Where next for stroke research?" 7th ESO Edinburgh Stroke Research Workshop, 26th February 2020, Edinburgh, UK. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Professor Joanna Wardlaw talk 'Research in Vascular Dementia 2019-20'. Scottish Dementia Research Consortium (SDRC), Research in Vascular Dementia 2019-20, 7th September 2020, Virtual Session. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Joanna Wardlaw talk 'Research in Vascular Dementia 2019-20'. Scottish Dementia Research Consortium (SDRC), Research in Vascular Dementia 2019-20, 7th September 2020, Virtual Session. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Professor Richard Wade-Martin gave a talk at the Longevity Forum at Oriel College, Oxford |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 12 November, Professor Richard Wade-Martin gave a talk at the Science Summit, Longevity Forum at Oriel College, Oxford |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://thelongevityforum.com/the-longevity-week/ |
| Description | Professor Richard Wade-Martins gave a talk at the Oxford Stem Institute Symposium 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | on 18 September, Professor Richard Wade-Martins gave a talk at the Oxford Stem Institute Symposium 2019. Stems Cell: From Mechanism to Therapy |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.stemcells.ox.ac.uk/home |
| Description | Professor Richard Wade-Martins gave an ARUK Target Drug Discovery talk along with Dr George Tofaris |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 12 November, Professor Richard Wade-Martins gave an ARUK Target Drug Discovery talk along with Dr George Tofaris |
| Year(s) Of Engagement Activity | 2019 |
| Description | Professor Thompson Robinson talk 'Rates, Risks and Routes to Reduce Vascular Dementia update', London, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Thompson Robinson, London and KSS LCRN network meeting, 5th May 2019. Title 'Rates, Risks and Routes to Reduce Vascular Dementia update'. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Profile on Nora Bengoa-Vergniory and workplace |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Recorded in 2019, Dr Nora Bengoa-Vergniory was filmed over a day for a Basque TV programme called "Vascos por el mundo". She was shown in her daily workplace inside the Wade-Martins lab. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.eitb.eus/es/television/programas/vascos-por-el-mundo/ |
| Description | Psychometric evaluation the cognitive assessment in UK Biobank: Dementias Platform UK Cognitive Assessment. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation at Alzheimer's Research UK |
| Year(s) Of Engagement Activity | 2018 |
| Description | Pub quiz in aid of Parkinson's Research |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Siv Vingill, Melanie Witt, Dayne Beccano-Kelly, Nora Bengoa-Vergniory and Melanie Witt took part in pub quiz held at the Barleycorn pub near Andover raising funds for Parkinson's research in Oxford. They met with supporters and talked about their work. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.opdc.ox.ac.uk/oxford-parkinson-s-disease-centre-members-raise-funds-for-their-research-a... |
| Description | Pub quiz in aid of Parkinson's Research |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Richard Wade-Martins, Dayne Beccano-Kelly, Nora Bengoa-Vergniory, Marta Madureira, Brent Ryan, Matthieu Trigano, Siv Vingill, along with OPDC administrator, Lorraine Dyson, travelled to the Royal Oak, Goodworth Clatford in Andover to take part in a quiz night in aid of Parkinson's research. They met with supporters and talked about their work. OPDC supporters Bobbie Coelho, Mary Doherty and Dawn Huntly presented a cheque for £2000 to Professor Richard Wade-Martins to support the work being carried out by the OPDC into Parkinson's Disease. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/oxford-parkinson-s-disease-centre-support-charity-christmas-pub-quiz |
| Description | Q&A session at Rare Dementia Support Group |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Question and Answer session from patients and carers with a diagnosis of frontotemporal dementia |
| Year(s) Of Engagement Activity | 2017 |
| Description | Quinn, A.J. Warneford Hospital's Clinical Research Facility open day. May 2019. Investigating Neuronal Oscillations in Ageing and Dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | n/a |
| Year(s) Of Engagement Activity | 2019 |
| Description | Quinn, A.J., Green, G.G.R, Hymers, M. NeuroMatch online conference. Oct 2020. Delineating single subject oscillatory brain networks with Spatio-Spectral Eigenmodes. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | https://www.youtube.com/watch?v=ZN5On6Hb92Y |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.youtube.com/watch?v=ZN5On6Hb92Y |
| Description | Quote in national newspaper - article on Type 2 diabetes, statins and Alzheimer's |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | In July 2020 John Gallacher (DPUK Director) was asked to provide his thoughts on statins for Alzheimer's disease. His response was: Professor John Gallacher, the director of Dementias Platform UK at Oxford University, says: 'It's not unreasonable to hope there's a benefit in terms of dementia risk.'But can you prescribe them for dementia? At the moment, based on this evidence, I don't think you can.' DPUK was mentioned, highlighting the expertise and value we provide to the field. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dailymail.co.uk/health/article-8583441/Beat-type-2-diabetes-middle-age-fight-Alzheimers.... |
| Description | RCPsych Neuropsychiatry Annual Conference 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk given to conference entitled "Neuropsychiatric Genetics of Dementia and other Neurodegenerative Disorders: Implications for treatment, prevention and personalised psychiatry" |
| Year(s) Of Engagement Activity | 2019 |
| Description | Radio Interviews on Parkinson's |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Radio interview to raise awareness and Parkinson's fund raising sponsored event Raised awareness and money |
| Year(s) Of Engagement Activity | 2015 |
| Description | Rare Dementia Support Group Launch 2016 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Rare Dementia Support Fund created with the ambition to increase fundraising and extend the support service further, throughout the UK and beyond. Extremely well attended |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.nationalbrainappeal.org/rare-dementia-support-launch-event/ |
| Description | Raymont, V. Brookes University Ageing Well Event Can we prevent dementia? November 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | n/a |
| Year(s) Of Engagement Activity | 2020 |
| Description | Raymont, V. DPUK Great Minds Event May 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | n/a |
| Year(s) Of Engagement Activity | 2020 |
| Description | Recognized as an Expertscape World Expert in the Blood-Brain Barrier. Expertscape's PubMed-based algorithms placed Joanna in the top 0.1% of scholars writing about the Blood-Brain Barrier over the past 10years |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | https://twitter.com/Daily_Experts/status/1417385315556335616 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Recover academy |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Led a presentation and discussion on brain imaging in dementia to patient and carers and health professionals as part of the Greater Manchester Mental Health NHS Foundation Trust 'Recover academy'. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Reinvigorating health registries during COVID for rapid policy analyses. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Reinvigorating health registries during COVID for rapid policy analyses. Norwegian Health Registry Conference, Oslo, 16/11/21. Helse- og Kvalitetsregisterkonferansen 2021 | Keynote presentation. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.registerkonferansen.no/ |
| Description | Relations in biomedical research participation: Building a cross-cohort platform in the context of a national health system |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Atkinson, S., et al. 'Relations in biomedical research participation: Building a cross-cohort platform in the context of a national health system'. Paper Presentation, 13th Conference of the European Sociological Association, Athens, Greece. Audience: Sociology of health, public health, bioethics of public engagement and recruitment. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Representative at ATLAS HDR UK meeting - May 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | ATLAS stands for 'Access points to Tissue, Longitudinal data, Archives and Samples'. The Frontiers meeting aimed to answer the question '"Can we enable research by producing and maintaining an up-to-date tool that summarises the tissue, longitudinal study data, archives and samples ('resources') in all viable UK collections and data harmonisation repositories?" |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://proposals.epi.bristol.ac.uk/?q=node/129787 |
| Description | Representative at invitation-only working group - Population Research Resource workshop - ESRC, MRC and Wellcome cohort data meeting - May 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | John was invited to a one-day workshop where the ESRC, MRC and Wellcome Trust aimed to engage with a broad range of users of longitudinal studies and gain insight into the different needs of the user communities. The outcome of this workshop will enable funders to reflect upon how these needs could best be met in order to enhance the value of the suite of longitudinal resources that exist in the landscape. They discussed domains including data/sample discoverability, sharing best practise, setting strategic objectives, interdisciplinarity and co-ordination across studies, training, security and outreach. This was by no means an exhaustive list, enabling user communities to shape the discussion around maximising population research resources is one of the aims of the workshop. The workshop was held at the Wellcome Trust in London, from 10:00 - 15:30 on Friday the 24th of May. Space was limited and attendance was by invitation only. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Research Participants perspectives on recruitment from existing cohorts in dementia research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Atkinson, S., Conference Poster: Research Participants perspectives on recruitment from existing cohorts in dementia research AAIC, June 2017, London. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Research Participants perspectives on recruitment from existing cohorts in dementia research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Atkinson, S., et al. 'Research Participants perspectives on recruitment from existing cohorts in dementia research'. Poster Presentation, Alzheimer Association International conference, London, UK. Audience: Public health, bioethics of public engagement and recruitment. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Research Spotlight on our researcher, Pavandeep Rai for Black History Month |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | As part of Black History Month, which is celebrated nationwide every year to recognise the contributions that people from BAME backgrounds have made to this country. The spotlight was on one of our Researchers - Pavandeep Rai, a Postdoctoral Research Scientist working in the Wade-Martins Group. Pavandeep is working at the forefront of an industry/academia collaborative project aimed at developing potential new drugs to treat Parkinson's. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dpag.ox.ac.uk/news/research-spotlight-for-black-history-month-pavandeep-rai |
| Description | Research spotlight on Career Career Development Fellow, Dayne Beccano-Kelly |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | As part of the university of Oxford series in celebrating 'amazing people at Oxford who you should know about', ScienceBlog talked to Dayne Beccano-Kelly, an electrophysiologist and a Career Development Fellow in Oxford Parkinson's Disease Centre, in the department of Physiology, Anatomy and Genetics at Oxford University. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.ox.ac.uk/news/science-blog/research-spotlight-%E2%80%98i-want-get-high-enough-chain-pull-... |
| Description | Researchers participate in the annual Walk for Parkinson's in Oxford |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | On Sunday 19th September, a team of researchers and supporters from the OPDC & Wade-Martins Group took part in the annual Walk for Parkinson's in Oxford organised by Parkinson's UK, in conjunction with the Parkinson's UK Oxford Branch Members of the OPDC completed either the 6 or 2 mile walk on the tracks and paths through the woodland at Wytham Woods to help raise funds towards vital research into Parkinson's Disease. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dpag.ox.ac.uk/opdc/news/latest/opdc-participate-in-the-annual-walk-for-parkinson2019s-ox... |
| Description | Rittmann, T. (14th May 2018). The story of a noisy brain. Pint of Science, Annual Science Festival, Castle Bar, Cambridge, UK |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Increase awareness. Discuss science with general public |
| Year(s) Of Engagement Activity | 2018 |
| Description | Robustly social, meaningfully ethical: Embedding social science in Dementias Platform UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Atkinson, S., Conference Poster: Robustly social, meaningfully ethical: Embedding social science in Dementias Platform UK. CIPH Showcase 2016, Cambridge, & DPUK Conference 2016, London. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Rowe - Cambridge Neuroscientists involved in large multi-centre Alzheimer's study. Cambridge Neuroscience News, UK (2016) |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Rowe, J. B. (22th August 2016). Cambridge Neuroscientists involved in large multi-centre Alzheimer's study. Cambridge Neuroscience News, UK. http://www.neuroscience.cam.ac.uk/news/article.php?permalink=886b81aa3d |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.neuroscience.cam.ac.uk/news/article.php?permalink=886b81aa3d |
| Description | Rowe - Cambridge Science Festival (2017) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Lecture at Cambridge Science Festival |
| Year(s) Of Engagement Activity | 2017 |
| Description | Rowe - Cambridge Science Festival 2018 - Molecules to Memory - Advances in Dementia Research, hosted by ARUK local network |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | public talk at Cambridge Science Festival |
| Year(s) Of Engagement Activity | 2018 |
| Description | Rowe - Cambridge extends world leading role for medical imaging with powerful new brain and body scanners. Cambridge Neuroscience News, UK (2016). |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | • Rowe, J. B. (25th October 2016). Cambridge extends world leading role for medical imaging with powerful new brain and body scanners. Cambridge Neuroscience News, UK. http://www.neuroscience.cam.ac.uk/news/article.php?permalink=fe046fcc97 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Rowe - Cambridge extends world leading role for medical imaging with powerful new brain and body scanners. University of Cambridge News for Medical Design Technology (2016) |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Rowe, J. B. (24th October 2016). Cambridge extends world leading role for medical imaging with powerful new brain and body scanners. University of Cambridge News for Medical Design Technology. http://www.cam.ac.uk/research/news/cambridge-extends-world-leading-role-for-medical-imaging-with-powerful-new-brain-and-body-scanners |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.cam.ac.uk/research/news/cambridge-extends-world-leading-role-for-medical-imaging-with-pow... |
| Description | Rowe - FTD Carers' Meeting, Department of Clinical Neurosciences, University of Cambridge, UK (2014) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Rowe, J. B. (24th March 2014). FTD Carers' Meeting, Department of Clinical Neurosciences, University of Cambridge, UK. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Rowe - FTD-UK Annual Meeting (2017) - Debate |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A discussion of imaging's contribution to FTD diagnosis, prognosis and stratification |
| Year(s) Of Engagement Activity | 2017 |
| Description | Rowe - For the Dementia Awareness Week: Professor James Rowe of @CamNeuro on Cambridge s role in dementia research. University of Cambridge, (2017). |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Rowe, J. B. (17th May 2017). For the Dementia Awareness Week: Professor James Rowe of @CamNeuro on #Cambridge's role in dementia research. University of Cambridge, Cambridge TV @cambridgetvnews (Twitter Video). https://twitter.com/cambridgetvnews/status/864790164861800448; awareness for dementia |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://twitter.com/cambridgetvnews/status/864790164861800448 |
| Description | Rowe - Her tester programleder Emma < |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Rowe, J. B. (14th May 2016). Her tester programleder Emma <>. Kristin Granbo for NRK News. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.nrk.no/dokumentar/xl/her-tester-programleder-emma-_smart-drug_-1.12916450 |
| Description | Rowe - Look East. The latest news, sport and weather for the East of England. BBC One. (Feature about PSP Association) (2017) |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Rowe, J. B. (16th May 2017). Look East. The latest news, sport and weather for the East of England. BBC One. (Feature about PSP Association). |
| Year(s) Of Engagement Activity | 2017 |
| Description | Rowe - Misplace in Space (2016-2017) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Rowe, J. B. (1st-6th September 2017). Misplaced in Space. Emily Fisher, Work by MA students shown in the MA Degree Show 2017 with work related to individual's experience to live with dementia. Norwich University of the Arts, UK. http://www.nua.ac.uk/ma-degree-show-catalogue-2017/emily-fisher/; An interactive exhibition about living with Dementia, |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.nua.ac.uk/ma-degree-show-catalogue-2017/emily-fisher/ |
| Description | Rowe - NIMROD study. BRC Communications, R D Newsletter, Cambridge Biomedical Research Centre (2017) |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Rowe, J. B. (6th October 2017). NIMROD study. BRC Communications, R&D Newsletter, Cambridge Biomedical Research Centre. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Rowe - The new scanners that can really get inside your head. Robin McKie for the Guardian (2016). |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Rowe, J. B. (23rd October 2016). The new scanners that can really get inside your head. Robin McKie for the Guardian. https://www.theguardian.com/science/2016/oct/23/powerful-brain-scanners-cambridge-neuroscience |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.theguardian.com/science/2016/oct/23/powerful-brain-scanners-cambridge-neuroscience |
| Description | Rowe Group Member Dr NEGIN HOLLAND gave talk: Synaptic imaging in dementia and neurodegenerative disease @ Cambridge Imaging Festival |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | This is a meeting of users and experts within the Cambridge NHS and academic community. Results and data are shared as well as new perspectives and applications for novel imaging methods. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.mrc-cbu.cam.ac.uk/wp-content/uploads/2021/05/Programme-Cambridge-Imaging-Festival-2021.p... |
| Description | Rowe/Team - Cambridge Science Festival (2017) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | A lecture on the challenge of dementia as part of the Cambridge Science Festival |
| Year(s) Of Engagement Activity | 2017 |
| Description | Royal College of Physicians 'Women in medicine: a celebration' project |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Royal College of Physicians (RCP)'s 'Women in medicine: a celebration' project is a free exhibition of specially commissioned photographic portraits to honour contemporary and historical women in medicine. The project showcased a number of today's leading female clinicians and the women from the history of medicine who have inspired them. Prof Joanna Wardlaw is featured in the project alongside someone who inspired her, Marie Sklodowska Curie: https://www.rcplondon.ac.uk/projects/outputs/women-medicine-joanna-wardlaw-and-marie-curie |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.rcplondon.ac.uk/events/women-medicine-celebration |
| Description | STV Scotland Tonight programme, talk. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | STV Scotland Tonight programme, 2022, Thursday, April 21. "'It was so hard when Andrew went out the door for the last time'. |
| Year(s) Of Engagement Activity | 2022 |
| Description | SVD Research LinkedIn |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | SVD Research LinkedIn social media channel promoting work of the University of Edinburgh SVD Research groups, including publications, awards, press releases, recent vacancies and other associated activities, aiming to build an international network of professionals specialising in the SVD Research and promote the research to funding bodies, policy makers and industry professionals. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://uk.linkedin.com/in/svd-research-5aaa27199 |
| Description | Saving the NHS through Data Science |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Health and Care Research Wales conference, Cardiff |
| Year(s) Of Engagement Activity | 2018 |
| Description | School visit to give a talk |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | On 18th January, Naroa Ibarra Aizpurua gave a talk at the OIBC Biology Symposium held at St Edward's School in Oxford for 6th form students. |
| Year(s) Of Engagement Activity | 2023 |
| URL | http://stedwardsoxford.org |
| Description | SciScreen Dementia Event |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Rebecca Sims gave a public presentation on Dementia research before a free screening of the film "Away from Her", post-film discussion and free drinks reception. The purpose of the event is for scientists to engage with the general public for mutual benefit. The presentation was well received, and the discussions were lively. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Section on DPUK website to formally request stem cell lines |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | A section on iPSC resources for researchers on the DPUK website provides the opportunity for researchers to formally request over 100 stem cell lines derived from healthy and diseased individuals. This resource focused section is complemented by two detailed reports in the "Our impact" section of the web-site. |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.dementiasplatform.uk/for-researchers/expert-communities-1/stem-cells-network-1/ipsc-reso... |
| Description | Seminar talk at the AstraZeneca Neurosciences, Cambridge UK |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | In November 2020, Prof Richard Wade-Martins gave a talk at the AstraZeneca Neurosciences, Cambridge UK |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://azneuro.com/ |
| Description | Seminar talk at the Biomedical Research Foundation Academy of Athens, Greece |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In March 2020, Prof. Richard Wade-Martins gave a seminar talk at the Biomedical Research Foundation Academy of Athens, Greece |
| Year(s) Of Engagement Activity | 2020 |
| URL | http://www.bioacademy.gr/events |
| Description | Session Chair: Cognition at Brain 2022 Conference |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chaired session on congnition with research presentations on: 1. Transdiagnostic approaches to cognitive disorders and their underlying brain pathology 2. Dissociable brain microstructural diffusivity changes underlying visual short -term memory deficits in Alzheimer's disease. 3. Bayesian Brains and the origin of functional disorders. 4. 'Socioeconomic status impacts cognitive and socioemotional processes in healthy ageing: evidence from Latin American older adults. 5. Noradrenergic treatment of cognitive disorders: big news from the blue spot. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://thebrainconference.co.uk/brain-conference-schedule/ |
| Description | Session chair and presenter at Bulgarian conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sarah Bauermeister hosted an Oxford-led scientific session covering topics such as 'methods for the diagnosis of preclinical Alzheimer's disease' and 'Acceleration of dementia research through Dementias Platform UK'. The presentation allowed engagement with a brand new country audience for DPUK. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Set up of new Parkinson's UK research seminar series |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | During the COVID-19 pandemic, Natalie Connor-Robson helped set up and organise a new online Parkinson's UK seminar series for researchers. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Short interview on 'data-driven procedures for disease clustering' for LinkedIn - FORUM workshop, Autumn 2020 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | John Gallacher produced an interview for the LinkedIn page of the FORUM workshop series (more information about this series is below). He was invited to record a short 2-3 minute video on 'Data-driven approaches to disease clustering' for the organisers to share on private LinkedIn group for attendees prior to the workshop.' He reflected on personal experience working in this area, the opportunities for cross-sector working and/or the one key take away or impact he'd like from this workshop. Multimorbidity: Cross-sector opportunities for developing new interventions for patients with multiple long-term conditions (MLTC) Background and aims An estimated 54% of people over the age of 65 in the UK have multiple long-term health conditions, often referred to as multimorbidity.1 As the population ages, the prevalence of multimorbidity is expected to increase to two-thirds of all adults aged over 65 by 2035. However, despite growing evidence for the occurrence of common 'clusters' of chronic diseases, a lack of understanding of the biological mechanisms underlying these clusters, viable drug targets, and the difficulties of conducting clinical trials with patients with multiple conditions all limit the ability to develop treatments for this heterogeneous patient population. As a result, most treatments still typically target single conditions, with little consideration for the underlying root causes within disease clusters.2 Together with a paucity of medical guidance on multimorbidity, this increases the likelihood of polypharmacy and associated adverse drug reactions (ADRs). ADRs themselves are a significant contributing cause of morbidity, and have been estimated to account for up to 8% of unplanned hospital admissions in the UK,3 costing the NHS approximately £1 bn-£2.5 bn annually.4Covid-19 has further highlighted these issues; we know that people with certain long-term conditions are at risk of poorer outcomes from covid-19, and MLTCs have been suggested as indicators of severe adverse outcomes. We need to better understand the patterns and drivers of interactions between conditions in relation to outcomes for patients with MLTCs. In 2018, the Academy of Medical Sciences produced a working group report that set out a series of research priorities to help realise the ambition of understanding and treating MLTC in a way that maximises benefits to patients while minimising potential harms.4Three of these research priorities will contribute to the development of effective interventions for patients with MLTC: 1. Adopting data-driven approaches to identify true disease clusters, to help inform research efforts, prioritise the most promising areas and understand patient populations to ensure research remains relevant. 2. Understanding the biological mechanisms that link disease clusters, to reveal new opportunities for drug development, novel drug targets and the potential to treat multiple conditions with single pathways and reduce polypharmacy. 3. Incorporating patients with more MLTC into clinical trials, to ensure that treatments are proven effective and safe in these patients, who are the population most likely to be seen by clinicians in practice. 1 Kingston et al. 2018, "Projections of multimorbidity in the older population in England to 2035: Estimates from the Population Ageing and Care Simulation (PACSim) model", Age and Ageing, vol. 47, no. 3, pp. 374- 380. 2 Fortin et al. 2005, "Prevalence of multimorbidity among adults seen in family practice", Annals of Family Medicine, vol. 3, no. 3, pp. 223-228. 3 NICE Medicines and Prescribing Centre. Medicines Optimisation: The Safe and Effective Use of Medicines to Enable the Best Possible Outcomes; NICE Guideline 5; NICE: London, UK, 2015; Available online: https://www.nice.org.uk/guidance/ng5/resources/medicines-optimisation-thesafe-and-effective-use-of-medicines-to-enable-the-best-possible-outcomes-pdf-51041805253 4 Kongkaew et al. 2008, "Hospital admissions associated with adverse drug reactions: A systematic review of prospective observational studies", Annals of Pharmacotherapy, vol. 42, no. 7-8, pp. 1017-1025. These priorities are multi-disciplinary, cross sectoral and are all necessary steps to develop novel safe and effective treatments for patients with MLTC. As such, this workshop will examine these three research priorities and discuss how opportunities to enhance MLTC research can be seized. During these workshops we aim to identify the key opportunities in each of these areas, as well as what actions the research community needs to take to respond. These workshops will convene researchers and policymakers across academia, industry, the NHS, funding bodies, regulatory agencies and others to: ?Bring together different sectors to discuss the key opportunities and foreseeable challenges of embedding MLTC into research programmes that will lead to better interventions for patients. ?Support an enhanced awareness of, and appreciation for, the importance of a MLTC approach to research across multiple stakeholders, and the potential benefits for patient outcomes and commercial opportunities. ?Explore possible next steps, actions or changes that need to be made to support and progress the MLTC research agenda, including identifying who would be responsible for taking forward such steps. ?Build relationships across sectors between researchers, SMEs, large pharma, funders and other stakeholders to facilitate a unified approach to accelerating research into developing interventions for patients with MLTC. The Academy of Medical Sciences' FORUM provides an independent platform for senior leaders from across academia, industry, government, and the charity, healthcare and regulatory sectors to come together and take forward national discussions on scientific opportunities, technology trends and associated strategic choices for healthcare and other life sciences sectors. The FORUM network helps address our strategic challenge 'To harness our expertise and convening power to tackle the biggest scientific and health challenges and opportunities facing our society' as set in our Strategy 2017-21. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://acmedsci.ac.uk/more/events/multimorbidity-a-new-research-pathway |
| Description | Short video on Smartphone app #OxfordAI |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | OPDC approached by Oxford University to make a film about our smartphone app to monitor Parkinson's. Film produced as part of #OxfordAI campaign and released onto Oxford University twitter (>486k followers), Facebook (>3.5M followers) and website. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.facebook.com/the.university.of.oxford/videos/2153105401670113/UzpfSTIzMzAxMDc0MDQ3ODAyNz... |
| Description | Siv Vingill Talk at 2018 JPND collaborators meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Talk by Siv Vingill at JNPD meeting, Leuven Title: Pre-formed fibrillar a-synuclein induce aggregation of endogenous a-synuclein in iPSC-derived neurons 'Conference': The meeting in December 2018 was attended by international collaborators on the project. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Siv Vingill Talk at 2019 - CRISPR in Drug Discovery 2019: From Targets to Therapeutics |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | Talk at ELRIG meeting 2019 - CRISPR in Drug Discovery 2019: From Targets to Therapeutics "ELRIG is a not-for-profit organisation, based in the UK. We are leaders in the provision of scientific meetings and conferences; bringing together academic and biopharma industry experts and thought leaders to exchange ideas and information." Target Validation"Modelling alpha-synuclein Parkinson's pathology in CRISPR-engineered human iPSC-derived dopamine neurons". Dr Siv Vingill, University of Oxford |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://elrig.org/2019-ge-programme/ |
| Description | Siv Vingill gave a talk at the JNPD collaborators meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 1-3 October, Siv Vingill gave a talk at the JNPD collaborators meeting. Professor Richard Wade-Martins also attended. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Siv Vingill presented a poster at JNPD meeting Brussels 27-28th Nov 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 27-28 November, Siv Vingill presented a poster at the JNPD meeting in Brussels. Title: aSynProTec: Alpha-synuclein pathology propagation in Parkinson's disease and quest for novel protective strategies |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.neurodegenerationresearch.eu/ |
| Description | Social media post and video to celebrate Women in Science Day |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In February 2022, researchers from the Wade-Martins lab participated in a video celebrating Women in Science day |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.youtube.com/watch?v=U0yGdxZ7k2A |
| Description | Social media post as Naroa Ibarra Aizpurua won an online image competition for her ICC image of iPSC-derived midbrain neuron & astrocyte co-cultures. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In November 2021, Naroa Ibarra Aizpurua won an online image competition for her ICC image of iPSC-derived midbrain neuron & astrocyte co-cultures. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/PKILifeScience/status/1456633666193481735 |
| Description | Social media post as part of DPUK advent calendar featuring Professor Richard Wade-Martins |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In December 2021, there was a social media poster on Day 22 of #DPUKadvent featuring Prof Richard Wade-Martins Richard is Professor of Molecular Neuroscience @UniofOxford and principle investigator of @WadeMartinsLab at @OxfordPDCentre. Richard also leads DPUK's Stem Cell Network - read more about it here: https://dementiasplatform.uk/research-hub/stem-cell-network |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/DementiasUK/status/1473616556676554752 |
| Description | Social media post highlighting posters featured in BNA 2021. |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Social media post highlighting the poster displayed at BNA 2021 by Nora Bengoa-Vergniory, Brent Ryan, Kaitlyn Cramb, William McGuinness, Bryan Ng, and Maria Claudia Caiazza |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/OxfordPDCentre/status/1430823145347420160 |
| Description | Social media post to announce new OPDC website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In March 2021, a new OPDC website was announced and shared via social media. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/OxfordPDCentre/status/1376504552057417733 |
| Description | Social media post to highlight World Parkinson's Day |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | On 11 April, a social media post was shared highlighting World Parkinson's Day and promoting the new OPDC website. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/OxfordPDCentre/status/1381163333286572033 |
| Description | Social media post to highlight new video |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | We shared a new video titled, 'The immunological side of neurodegeneration: a focus on #Parkinson's disease' by Stefania Guissani |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/OxfordPDCentre/status/1479042121009188866 |
| Description | Social media post to promote the stem cell work of PhD researcher Ajantha Abey |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In October 2021, there was a social media post to promote the stem cell work of PhD researcher Ajantha Abey and link to news item |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dementiasplatform.uk/research-hub/stem-cell-network/meet-the-phd-student-investigating-w... |
| Description | Social media post to promote the stem cell work of PhD researcher Naroa Ibarra Aizpurua |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In October 2021, there was a social media post to promote the stem cell work of PhD researcher Naroa Ibarra Aizpurua and link to news item |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dementiasplatform.uk/research-hub/stem-cell-network/can-a-type-of-supportive-brain-cell-... |
| Description | Social media post to promote the stem cell work of PhD researcher Quyen Do |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In October 2021, there was a social media post to promote the stem cell work of PhD researcher Quyen Do and link to news item |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dementiasplatform.uk/research-hub/stem-cell-network/growing-mini-brains-to-study-parkins... |
| Description | Social media post welcoming new staff and students to the Wade-Martins lab |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Throughout 2022, social media messages were posted welcoming news members of the Wade-Martins lab and linking through to the profile pages on the website. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Speaker & Organizer at Research Information Day 2023: PSP Association |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Co-organizer and speaker at 2023 PSP Association Research Symposium https://www.pspassociation.org.uk/research-information-day-2023/ |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.pspassociation.org.uk/research-information-day-2023/ |
| Description | Speaker at 2018 Korean Dementia Association (KMA) Annual Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Outcomes and impacts include a strengthened relationship with professionals in Korea to support the work of both DPUK and DPKorea, and the Korean government's initiative in tackling dementia. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Speaker at AlzSoc, UKRI and NIHR UK Dementia Care Research Summit - Feb 2020, Leeds |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Third sector organisations |
| Results and Impact | John Gallacher was invited to speak at a national conference Dementia Research Care conference. The aim of the Summit was to reflect on the progress we (the field) have made, take stock of where we've got to now, and set out plans and ambitions for the next decade. The format of the day was plenty of short presentations along with small group and wider group discussion to set out new directions. John gave a presentation in the 'Session Sharing - Research Data' section, where the aim is to explore how we can collaborate better on dementia care research data, particularly about the contribution initiatives John is involved in can build towards care. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Speaker at Dublin Neurology update meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | Speaker at Primary Progressive Aphasia: BNPA Annual Meeting, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Speaker at Public panel debate with Alzheimer's Society 'How can we beat dementia in the next twenty year |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | N/a |
| Year(s) Of Engagement Activity | 2016 |
| Description | Speaker at launch of UK Dementia Platform |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | Yes |
| Geographic Reach | Regional |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | Oxford plays a significant role in the partnership and Oxford Neuroscience researchers lead a number of projects. This was reflected in the scientific programme of launch day. Simon Lovestone (Psychiatry) gave a talk on the NIHR-MRC Dementia Deep and Frequent Phenotyping Feasibility Study while Richard Wade-Martins (DPAG) spoke on the UK Stem Cell Network. Coverage in the media |
| Year(s) Of Engagement Activity | 2014 |
| URL | http://www.dementiasplatform.uk/ |
| Description | Speaker at the University of Bordeaux on DPUK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | John presented at the University of Bordeaux, where a DPUK cohort PI (Prof Carole DuFouil, MEMENTO) is based. The presentation title: "Dementias Platform UK: Developing the experimental medicine pipeline". The audience included students (masters, PhD), postdoctoral fellows, biostatisticians, researchers, professors, lecturers and data managers. This talk boosted the awareness of DPUK in France, as observed in our website traffic statistics, and strengthen a relationship with a key cohort collaborator. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.isped.u-bordeaux.fr/ |
| Description | Speaker at the Yonsei-Wonju International Conference on Ageing and Dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The Yonsei Wonju Health System, in cooperation with the Wonju Severance Christian Hospital (a 2018 PyongChang Winter Olympics designated hospital), has been providing the best medical services in central South Korea, and is presently leading the future of medical services. Moreover, the Yonsei Wonju College of Medicine, celebrating its 40th anniversary in 2018, boasts superior teaching staff and high-tech academic facilities, and through the systematic medical education it provides, and research that has produced future medical manpower, the organization has contributed to medical development. As part of this effort, the International Symposium of Yonsei Wonju Health System is being staged to serve as the backdrop for academic exchange among renowned specialists in the field of precision medicine along with big data. Proposed session details are as follow: · Date: April 12th, 2018 · Session 1. What Is the Good of a Science Platform? · Proposed Lecture Title: Dementias Platform UK (DPUK) Outcomes and impacts include a strengthened relationship with professionals in Korea to support the work of both DPUK and DPKorea, and the Korean government's initiative in tackling dementia. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.yuhs.or.kr/en/inter_healthcare_center/inter_health_severance/intro/ |
| Description | Speaker to 6th ESRC International Symposium - 'Biopsychosocial determinants of cognitive ageing and dementia: perspectives from the UK, US and Japan' |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | John Gallacher was invited to a one-day event "Biopsychosocial determinants of cognitive ageing and dementia: perspectives from the UK, US and Japan" on Wednesday, 6 November at Friends House, London, which brought together researchers from Japan and the UK who are working on cognitive ageing and dementia. This event will be followed by a two-day data harmonisation workshop for Early Career Researchers (PhD students and postdocs). He was asked to speak at this event to showcase the ongoing progress made by DPUK to an international audience, and also act as chair of a panel discussion. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.ucl.ac.uk/epidemiology-health-care/events/2019/nov/international-symposium-biopsychosoci... |
| Description | Speaker: MRI in dementia, Cambridge Dementia Course |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Speaking Cambridge Dementia Course: MRI in dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Speaking at EAN, Copenhagen, Focal dementias, Convener, lecturer |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Speaking re fluid biomarkers in AD. Educational Workshop. AAIC, Toronto |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Speaking re young onset dementia: Royal college of Physicians, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Specialist PSP Sub-group @ Movement Disorder Society International Conference: UHF 7T Imaging |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Expert panel meeting on imaging and Progressive supranuclear palsy. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Study Participant Reunion |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | A reunion of cohort participants to celebrate 20 years of a study. Researchers presented the latest results. The day was covered by national radio (BBC Radio Scotland) |
| Year(s) Of Engagement Activity | 2019 |
| Description | Symposium Speaker at the Federation of Latin American and Caribbean Neuroscience |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In September 2022, Professor Richard Wade-Martins was a Symposium Speaker at the Federation of Latin American and Caribbean Neuroscience |
| Year(s) Of Engagement Activity | 2022 |
| Description | Symposium on Big Data in Healthcare. Distributed team science: real world and cohort data |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Partnership between Weizmann Institute of Science and Nature Medicine, Tel Aviv |
| Year(s) Of Engagement Activity | 2019 |
| Description | Synaptic Health Symposium |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | A one-day workshop, and shorter follow up meetings, to engage academic and industry partners in Synaptic Health Research |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/for-researchers/expert-communities-1/synaptic-health-community |
| Description | Taking a new look at the risk factors for Alzheimer's disease |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Media article on publication of Multiplex Model in Nature Neuroscience - providing information on how the genes that have been identified as risk factors impact on other genes to trigger Alzheimer's |
| Year(s) Of Engagement Activity | 2020 |
| Description | Taking part in the Poster Day 'A Year of Progress' by 2nd Year Graduate Students |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | On the 18th of November, Naroa Ibarra Aizpurua created a poster presentation to share her research at the 2021 Poster Day 'A Year of Progress' by 2nd Year Graduate Students |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dpag.ox.ac.uk/news/winners-of-the-dpag-student-poster-day-2021-announced |
| Description | Talk - Methods in longitudinal dementia research (MELODEM) Annual Meeting 2019, US |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Discussion with experts in longitudinal data analysis for dementia research |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://sites.isped.u-bordeaux2.fr/melodem2/Portals/0/Meetings/MELODEM_SSRC_Progress_Meeting2019.pdf |
| Description | Talk - WIN Neurodegeneration symposium, Oxford, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | To present research outcomes |
| Year(s) Of Engagement Activity | 2018 |
| Description | Talk at - Alzheimer's Association International Conference 2021, Dr Maura Malpetti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Microglial activation and atrophy in frontal cortex predict executive dysfunction in frontotemporal dementia" - Alzheimer's Association International Conference |
| Year(s) Of Engagement Activity | 2021 |
| Description | Talk at Logikk IT computing consultants London: How AI may help solve the dementia crisis: A Dementias Platform UK (DPUK) & University of Oxford Project |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | Presentation of DPUK active projects and the DPUK Data Portal to industry reserachers. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Talk at NHS R&D Forum Conference, Wales |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | John delivered a talk on the CaPS cohort as PI of the study, and long-term collaborator of his colleague Professor Peter Elwood. Talk - 'How research practice has changed: insights from the Caerphilly Prospective Study' About the origins of the study, and what it was like trying to do research back then, reflecting on what has changed (for good or bad) and what has been learnt along the way. They will be familiar with way research is undertaken now (in general or maybe specific terms) but may not have been around to have witnesses all the about the changes in research governance, methods, funding etc. Exploring some of the history using the study as the case example may be of great interest. Keen to nod to the fact we're celebrating 70 years of the NHS and recognise research practice has also seen some changes over that time. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.annualrdforum.org.uk/2018-programme/ |
| Description | Talk at Parkinson's UK Branch Richard Wade-Martins |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Prof Richard Wade-Martins on the latest projects at the Oxford Centre for Parkinson's Disease Research |
| Year(s) Of Engagement Activity | 2016 |
| Description | Talk at UCL Symposium - Parkinsons Disease |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk on "MRI-based detection of early stage Parkinson's disease" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Talk at a workshop with AMED on Ageing Society |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Talk was in the 'European project' section of the workshop on ageing, entitled: 'DPUK: a PPP on a mission to harness new infrastructure to accelerate dementia research in UK'. Representatives from DPUK's partners (eg Janssen) were in attendance and sparked discussion in further collaboration. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.amed.go.jp/en/ |
| Description | Talk at tea club for people with mild memory problems |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Invited talk based on the research carried out via the DPUK platform "How to keep your brain healthy" coordinated by BRC NIHR and EPAD |
| Year(s) Of Engagement Activity | 2020 |
| Description | Talk at the Biomedical Research Foundation Academy of Athens, Greece March 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Richard Wade Martins gave a talk at the Biomedical Research Foundation Academy of Athens, Greece in March 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | http://www.bioacademy.gr/about |
| Description | Talk at the HOPE Conference for Parkinson's Research, Paris Jan 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Richard Wade-Martins gave a talk at the HOPE Conference for Parkinson's Research, Paris 29-31 Jan 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://hope2020.sciencesconf.org/ |
| Description | Talk at the PerkinElmer UK High-Content Screening User Group Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 29th September 2022, Naroa Ibarra Aizpurua gave a talk at the PerkinElmer UK High-Content Screening User Group Meeting in Madrid. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Talk at the UK MRI dementia conference 2019, St Anne's College, University of Oxford |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The talk entitled "Harmonising MR analysis across sites" presented literature background and own preliminary data and generated valuable discussion and feedback from the audience. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Talk at the University of Bath, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | In February 2023, Professor Richard Wade-Martins was invited to give talk at the University of Bath, UK |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.bath.ac.uk/ |
| Description | Talk by Carol Williams 'Rates, Risks and Routes to Reduce Vascular Dementia update',Basingstoke, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk by Carol Williams 'Rates, Risks and Routes to Reduce Vascular Dementia update'. Wessex regional stroke meeting, Basingstoke 6th March 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Talk by Dr M Malpetti at (ISTAART) Scientific Meeting: What have we learnt from PET in FTD in the last 10 years? |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "What have we learnt from PET in FTD in the last 10 years" - ISTAART FTD and Neuroimaging PIAs webinar: An update on neuroimaging in frontotemporal dementia (virtual event) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Talk by Dr M Malpetti at Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) Scientific Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk title: Neuroinflammation in medial temporal regions predicts cognitive decline in dementia with Lewy bodies |
| Year(s) Of Engagement Activity | 2021 |
| Description | Talk by Dr M Malpetti at Clinical Neurosciences Away Day, Cambridge University |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk title: Neuroinflammation in frontotemporal lobar degeneration: a target for treatment? |
| Year(s) Of Engagement Activity | 2021 |
| Description | Talk by Dr Rosalind Brown 'Rates, Risks and Routes to Reduce Vascular Dementia' |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk by Dr Rosalind Brown 'Rates, Risks and Routes to Reduce Vascular Dementia' CRN Eastern Stroke network meeting, 11th November 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Talk by Dr Una Clancy 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)', Exeter, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk by Dr Una Clancy 'Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)', UK joining forces west stroke conference, Exeter, 28th June 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Talk by Prof Joanna Wardlaw, Dr Ellen Backhouse and Dr Rosalind Brown 'Rates, Risks and Routes to Reduce Vascular Dementia', Telford, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | 'Rates, Risks and Routes to Reduce Vascular Dementia' TSA/BHF/Alz Soc ACTVaD study meeting. Talk by Prof Joanna Wardlaw, Dr Ellen Backhouse and Dr Rosalind Brown. December 5th 2019, UK Stroke Forum, Telford 2019 |
| Year(s) Of Engagement Activity | 2019 |
| Description | Talk by Prof Joanna Wardlaw, Dr Fergus Doubal, Dr Ellen Backhouse and Dr Rosalind Brown "Rates, Risks and Routes to Reduce Vascular Dementia' TSA/BHF/Alz Soc ACTVaD study meeting" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | 'Rates, Risks and Routes to Reduce Vascular Dementia' TSA/BHF/Alz Soc ACTVaD study meeting. Talk by Prof Joanna Wardlaw, Dr Fergus Doubal, Dr Ellen Backhouse and Dr Rosalind Brown. December 5th 2018, UK Stroke Forum, Telford 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Talk on Young onset dementia. Royal College of Physicians, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2016 |
| Description | Thames Valley Parkinson's Excellence Network Annual Meetings |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Michele Hu organised and presented at Thames Valley Parkinson's Excellence Network Annual Meetings |
| Year(s) Of Engagement Activity | 2015,2016,2017 |
| URL | https://www.parkinsons.org.uk/professionals/uk-parkinsons-excellence-network |
| Description | Thames Valley Parkinson's Excellence Network Newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | Newsletter for the TVEN distributed at Parkinson's clinics and at events. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.opdc.ox.ac.uk/_asset/file/tv-excellence-network-newsletter-june-2016.pdf |
| Description | The 7th European Stroke Conference - promotion of virtual meeting 31st August 2021. https://vjneurology.com/speaker/Joanna-Wardlaw/ |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | The Dementia UK Ecosystem and Innovations in biomarkers @ Cambridge Memory Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | The aim of this Cambridge-wide memory group is to encourage interaction between the many local labs working on the psychology/neuroscience of short- and long-term memory, both human and non-human. The talk given to this audience gave an overview of the key UK institutions and partners involved in dementia research aimed at identifying new biomarkers for plausibale clinical translation. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.memlab.psychol.cam.ac.uk/CAMM/index.html |
| Description | The Guardian - Terry Jones: I've got dementia. My frontal lobe has absconded |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | The Impact of Incidence Prior to Death on the Incidence of Dementia in individuals Aged 65 Years and Older |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Invited speak at Alzheimer's Association International Conference AAIC 2017 London. |
| Year(s) Of Engagement Activity | 2017 |
| Description | The Many Faces of Dementia - massive open online course (MOOC) |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | I was interviewed for an online course about the rarer forms of dementia, my interview related to the clinical features of frontotemporal dementia. I also performed the voice over and welcome to the course that appeared in the course trailer video. The course, due to start March 14th 2016 is a 'massive open online course' available at www.futurelearn.com/courses/faces-of-dementia. Over 12,000 people have registered for the course (as of 8th March 2016). |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.futurelearn.com/courses/faces-of-dementia |
| Description | The Row Fogo Centre for Research into Ageing and the Brain website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Being officially recognised as a Research Centre in 2018, The Row Fogo Centre for Research into Ageing and the Brain launched a new website. The website is directed in multiple audiences. Content includes a comprehensive description of the Centre research activity, updates on recent publications, news and organised events. The website contains information for PhD candidates and medical imaging researchers about related programmes and courses, and for visiting staff and students on how to join SVD Research Groups. The website gives a breadth of ways to fundraise and donate to support SVD research. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.ed.ac.uk/clinical-brain-sciences/research/row-fogo-centre |
| Description | The Secure Anonymised Information Linkage System |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | The Secure Anonymised Information Linkage System. Presentation to PHW Specialist Registrars, 04/08/21 |
| Year(s) Of Engagement Activity | 2021 |
| Description | The Secure Anonymised Information Linkage System |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The Secure Anonymised Information Linkage System. Edinburgh University Usher Institute, 05/07/21 |
| Year(s) Of Engagement Activity | 2021 |
| Description | The Times |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | I have given an interview to "The Times" newspaper published 22 March, 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | The conversation |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | https://theconversation.com/alzheimers-the-switch-on-moment-discovered-131810 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://theconversation.com/alzheimers-the-switch-on-moment-discovered-131810 |
| Description | The potential of dementia prevention research |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Prevention of dementia. Wide network of colleagues. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Three Data Portal training webinars |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Three training webinars were broadcast which offered free training to specific groups of scientists - university researchers and industry researchers - on the Data Portal. The webinars were well attended and sparked much interest and many questions from the researchers who attended. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.dementiasplatform.uk/for-researchers/researcher-training/online-training |
| Description | Tim Sandhu Talk @ CamBrain Cambridge Neuroscience Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | Oral presentation to junior researchers or those interested in neuroscience. Title "Learning under uncertainty in autism and anxiety" |
| Year(s) Of Engagement Activity | 2021 |
| Description | Tsvetanov - Talk presented at the meeting on "Your ageing brain. Use it or loose it". Meeting by Sevenoaks and Knole U3A Science Groups (2016) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Tsvetanov, K. (7th June, 2016). Talk presented at the meeting on "Your ageing brain. Use it or loose it". Meeting by Sevenoaks and Knole U3A Science Groups |
| Year(s) Of Engagement Activity | 2016 |
| Description | Twitter account for OPDC |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Active twitter feed for OPDC engages with other research groups and industry. Promotes our research, events, news and drives for study participants as well as highlighting relevant news items and publications. Jan 2019: 829 followers, average Impressions 10.6k per month |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018,2019 |
| URL | http://twitter.com/OxfordPDCentre |
| Description | Twitter post to celebrate International Women in Science Day 2021 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | On 11 February 2021, the Wade-Martins posted a photo to celebrate International Women in Science Day 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/WadeMartinsLab/status/1359831629653553154 |
| Description | Twitter post to highlight April issue and front cover of Trends in Biochemical Sciences & featuring the review article "Mitochondrial Dysfunction and Mitophagy in Parkinson's Disease: From Mechanism to Therapy" |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In March 2021, a Tweet was posted to highlight April issue and front cover of Trends in Biochemical Sciences & featuring the review article "Mitochondrial Dysfunction and Mitophagy in Parkinson's Disease: From Mechanism to Therapy" |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/OxfordPDCentre/status/1370335875738042376 |
| Description | Two cohort workshops |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The purpose of the cohort workshops is to engage the cohort study Principal Investigators and/or Data Managers in the development of resources that will best support them now and in the future. |
| Year(s) Of Engagement Activity | 2017 |
| Description | UCL DRC Lunchtime Meeting, 2015, Update on Insight 46 Progress |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Chris Lane gave a presentation on "Determining the causes and consequences of brain amyloidosis, atrophy and cerebrovascular disease: a longitudinal amyloid-PET/MRI study of the MRC British 1946 birth cohort" during the UCL Dementia Research Centre Lunchtime Meeting. This presentation provided updates to the department on the progress of Insight 46. |
| Year(s) Of Engagement Activity | 2015 |
| Description | UCL Queen Square Movement Disorders Centre Symposium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 9 June 2022, Professor Richard Wade-Martins gave a talk at the UCL Queen Square Movement Disorders Centre Symposium |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.ucl.ac.uk/ion/events/2022/jun/ucl-queen-square-movement-disorders-centre-symposium |
| Description | UCLH members meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | UK Biobank Winter Scientific Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dementia session at the UK Biobank Winter Scientific Conference |
| Year(s) Of Engagement Activity | 2022 |
| Description | UK Korea Neuroscience Symposium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | UKorea symposia bridge basic and clinical research within neuroscience. J Williams gave plenary lecture on 1st day 2019 symposium. The statements were shared via the UK-Korea social media channel (twitter @UKorea_Neuro). |
| Year(s) Of Engagement Activity | 2019 |
| Description | UK MED-BIO Partners meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Swansea were invited to attend the board meeting for the UK MED-BIO initiative hosted at Imperial College London, as both lead for the DPUK Data Portal development and as host of CIPHER. The meeting detailed how both Swansea research organisations as well as DPUK could work with UK MED-BIO, which has led to subsequent projects being commissioned and setup. |
| Year(s) Of Engagement Activity | 2016 |
| Description | UKSeRP Demonstration at Informatics for Health 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Swansea University took a team of researchers, technical staff and project support staff to Informatics for Health to showcase the SAIL Databank and UK Secure eResearch Platform. As part of the showcase, both research and technical staff performed demonstrations of the live UKSeRP infrastructure to a varied audience, and this included using UKSeRP tenant organisations as exemplar instances of UKSeRP, examples including SAIL, DPUK, and ADRC Wales. |
| Year(s) Of Engagement Activity | 2017 |
| Description | University of Oxford Concussions in Sport Event - Panelist |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Panelist at University of Oxford Concussions in Sport Event |
| Year(s) Of Engagement Activity | 2023 |
| Description | University of Reading SIAM-IMA student chapter conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Keynote invited speaker for University of Reading SIAM-IMA student chapter conference |
| Year(s) Of Engagement Activity | 2019 |
| Description | Using an advanced routine healthcare data systems to improve population health, clinical care and inform policy: the COVID-19 pandemic and beyond. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Using an advanced routine healthcare data systems to improve population health, clinical care and inform policy: the COVID-19 pandemic and beyond. Maurice Bloch Lecture, Glasgow University, 26/01/22. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://youtu.be/2B4Ak0YuOng |
| Description | Vascular risk factors in AD and other dementia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Personal invited to give talk at CoSTREAM Meeting of University of Cambridge. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Video interview |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | John Gallacher was recorded in a video interview about DPUK's collaboration with the ALSPAC cohort. It was viewed over 2000 times on social media. The video gained the attention of a key funder organisation in the sector - the Wellcome Trust. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://twitter.com/DementiasUK |
| Description | Video posted online & shared via social media to celebrate World Alzheimer's Day on 21 September 2022 |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | To coincide with World Alzheimer's Day on 21 September 2022, a video was posted online and shared on social media with an inside look into the Wade-Martins Laboratory. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://youtu.be/21es6CO8EkQ |
| Description | Video posted online & shared via social media to celebrate World Parkinson's Day on 11 April 2022 |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Richard Wade-Martins partipated in a video that was posted online & shared via social media to celebrate World Parkinson's Day on 11 April 2022 |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://youtu.be/VAPvuGtT5ek |
| Description | Video presentation on Youtube |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a video abstract of a recently published paper |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.youtube.com/channel/UClJJHH2xKQk8uZTC7-mJICg |
| Description | Visit to Parkinson's UK Aylesbury Branch |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | On 19/2/22, Dr Brent Ryan spoke to the Aylesbury Parkinson's UK group at their AGM on our work to find new drugs for Parkinson's |
| Year(s) Of Engagement Activity | 2022 |
| Description | Visit to local children's group to raise brain awareness |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | OPDC Career Development Fellow Dayne Becanno-Kelly, along with undergraduate student, Natalie Sepke, and former OPDC administrator Melanie Witt paid a visit to a local Woodcraft Folk Elfins group to talk about the research carried out by OPDC and to support better understanding of how the brain works. The children aged between 6-9 years listened carefully as Dayne introduced ideas of how the brain works, how sometimes things can go wrong in conditions like Parkinson's, and how we are trying to better understand what is happening so we can try to fix it. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.opdc.ox.ac.uk/opdc-visits-local-children-s-group-to-raise-brain-awareness |
| Description | Visits to local children's group for Dementia Awareness Week |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Career Development Fellows Natalie Connor-Robson, Dayne Becanno-Kelly and administrator Melanie Witt visited a local Woodcraft Folk Elfins group in Dementia Action Week to talk about our work to better understand the brain. The group of 6-9 year olds listened carefully as Dayne and Natalie introduced ideas of how the brain works, how sometimes things can go wrong in conditions like Parkinson's, and how we are trying to better understand what is happening so we can try to fix it. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.opdc.ox.ac.uk/opdc-visits-local-children-s-group-for-dementia-awareness-week |
| Description | Voice of Islam - Dementia |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Discussion on voice of islam broadcast on the theme of dementia to raise public awareness, especially within the Muslim community. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Voice of Islam Radio - Dementia Theme |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Voice of Islam broadcast discussion on dementia. |
| Year(s) Of Engagement Activity | 2021 |
| Description | WHO Bulletin Interview with Carol |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Interview with Carol Brayne: a life-course approach to prevent dementia https://apps.who.int/iris/handle/10665/272247 WHO Bulletin Interview with Carol |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://apps.who.int/iris/handle/10665/272247 |
| Description | WP7 Andrew Quinn presentation for Warneford Hospital's Clinical Research Facility open day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Andrew Quinn presentation for Warneford Hospital's Clinical Research Facility open day, held at St Anne's College, 20th May 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Website article commemorating 100 years of women in science, featuring DPhil student; Naroa Ibarra Aizpurua |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | In October 2020, Naroa Ibarra Aizpurua, DPhil student, was featured in an article commemorating 100 years of women in science, where she discussed her motivation to apply to the Oxford and the Wade-Martins lab. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dpag.ox.ac.uk/news/100-years-of-oxford-degrees-for-women |
| Description | Wellcome Trust Collaborators meeting on Tuesday 6th September |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | On 6th September the OPDC hosted a Wellcome Trust Collaborators meeting. It included talks from representatives from the Liss lab (University of Ulm), Kittler lab (UCL) , Magill Lab (UoO), Wade-Martins lab(UoO), and the Cragg lab (UoO). The programme included a poster session. Posters included form the Wade-Martins lab; Remya Raghavan Nair, Kaitlyn Cramb, Elena Britti, Benjamin Vallin, Sarah Franks, Quyen Do, and Helle Bogetofte |
| Year(s) Of Engagement Activity | 2022 |
| Description | Welsh Government AM visit |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Visit from Suzy Davies AM for tour of DRI offices and laboratories, meeting with all programme leads to discuss work undertaken |
| Year(s) Of Engagement Activity | 2019 |
| Description | Welsh presentation (Cardiff Science Society) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | A presentation was given in Welsh, by Alzheimer's Field Worker, Alun Meggy to the Cardiff Science Society on 21st November 2016. This was followed by questions and a discussion. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.cymdeithaswyddonolcaerdydd.org |
| Description | When I Grow up Day' at St Mary's CE Primary School - Dr K Stockton |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Dr Stockton spoke to junior school children about a career as a Doctor and Scientist. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Winner of the PerkinElmer "Think Neuro Art Image Competition" |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Naroa Ibarra Aizpurua was the Winner of the PerkinElmer "Think Neuro Art Image Competition" (PerkinElmer Life Sciences on Twitter: "Thanks to everyone who submitted designs for our #ThinkNeuroArt image contest. We're wowed by the scientific & artistic abilities of our customers! Congratulations to our winner, @NaroaIbaAiz for her ICC image shown here, of iPSC-derived midbrain neuron & astrocyte co-cultures. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/PKILifeScience/status/1456633666193481735 |
| Description | Women in Industry |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Industry/Business |
| Results and Impact | Presentation to Women in Industry event, providing overview of career, advice for women in STEM careers |
| Year(s) Of Engagement Activity | 2019 |
| Description | Women in Science film |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Women in Science video as one of the interviewees / case studies. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Woolrich, M.W. Keynote at the international conference OHBM. June 2020. Mapping Transient Dynamic Brain Networks |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | n/a |
| Year(s) Of Engagement Activity | 2020 |
| Description | Woolrich, M.W. NIH BRAIN transformative workshop 2021. Transient Dynamic Networks in Multimodal Brain Imaging |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | n/a |
| Year(s) Of Engagement Activity | 2021 |
| Description | Woolrich, M.W. UK Neurotechnologies for Dementia Workshop. Bucks, UK. May 2019. Dynamic Brain Networks |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | n/a |
| Year(s) Of Engagement Activity | 2019 |
| Description | Woolrich, M.W. University of Manchester Neuroimaging Seminar series. Oct 2020. Transient dynamic brain networks in M/EEG and fMRI |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | n/a |
| Year(s) Of Engagement Activity | 2020 |
| Description | Work with artist to produce cartoons of research |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Abstracts of posters were presented by DPAG Graduate Students at the start of their Second Year of DPhil Research Study. A cartoonist was on hand again to record the event and produced cartoons to illustrate the projects which were shared via social media. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://twitter.com/WadeMartinsLab/status/1074587251496095745 |
| Description | Working with Hong Kong University researcher on Data Portal analyses for publication |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Chinmoy Sarkar visited the Department of Psychiatry, University of Oxford,to meet with Dr Sarah Bauermeister and John Gallacher to discuss ongoing and future research projects involving data and analyses on the Data Portal. Post-meeting, Dr Sarkar was able to complete a paper on BE-COPD. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Working with Swansea University on the ARDC Secure eResearch Platform, Monash University |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Working with Swansea University on the ARDC Secure eResearch Platform, Monash University, 15/11/22 |
| Year(s) Of Engagement Activity | 2022 |
| Description | World Dementia Forum meeting Jan 2021 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Forum meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | World Innovation Summit for Health (WISH) Forum (February 2015) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Participated as panel member looking at issues of dementia funding and research, policy, and how best to better inform the public. A report was subsequently published based on the Summit meeting. |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.nhsq.info/app/media/4053 |
| Description | World Stroke Organisation Women in Stroke Initiative, 2021, showcasing the work of women who have made major contributions to advancing care of patients with stroke |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | https://www.world-stroke.org/news-and-blog/blogs/womeninstroke-initiative-our-nominees |
| Year(s) Of Engagement Activity | 2021 |
| Description | Young Onset Dementia: Different impact, positive solutions conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | This public meeting was held on 27th September, 2016. This was a recruitment opportunity. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.youngdementiauk.org/sites/default/files/Young%20Dementia%202016%20programme.pdf |
| Description | Young Onset and Rare Dementias 2014 event at House of Lords |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Awareness-raising event regarding young onset and rare dementias The event was attending by member of parliament and the House of Lords as well as charities, patient families and other organisations |
| Year(s) Of Engagement Activity | 2014 |
| URL | https://www.youngdementiauk.org/news/young-onset-awareness-event-house-lords |
| Description | iNEW's article "Three generations of a British family are helping the fight against Alzheimer's disease" |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | N/A |
| Year(s) Of Engagement Activity | 2017 |
| Description | led a session on macrophages and microglia in a Stem Cell Outreach workshop for GCSE school students |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Sally Cowley led a session on macrophages and microglia in a Stem Cell Outreach workshop for GCSE school students, Medical Sciences Teaching Centre, Oxford University |
| Year(s) Of Engagement Activity | 2018 |
| Description | news JDR |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | https://news.joindementiaresearch.nihr.ac.uk/971-2/ |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://news.joindementiaresearch.nihr.ac.uk/971-2/ |
| Description | presentation to Henley on Thames Parkinson's UK branch |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | On 26 May 2021, Nora Bengoa-Vergniory gave a presentation about her research to the Henley on Thames Parkinson's UK local branch |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://twitter.com/OxfordPDCentre/status/1397823354405634049 |
| Description | prof Joanna Wardlaw talk 'Stroke in the small vessels: recent clinical, mechanistic and potential therapeutic insights", The Eric Corey Raps Memorial Lecture 2021, The University of Pennsylvania Medical Centre, 10th Feb 2021, Pennsylvania, USA, virtual |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | prof Joanna Wardlaw talk 'Stroke in the small vessels: recent clinical, mechanistic and potential therapeutic insights", The Eric Corey Raps Memorial Lecture 2021, The University of Pennsylvania Medical Centre, 10th Feb 2021, Pennsylvania, USA, virtual |
| Year(s) Of Engagement Activity | 2021 |
| Description | symptomatic-drugs-for-cognitive-impairment-in-dementia-what-to-expect |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | https://www.dementiasplatform.uk/news-and-blogs/blog/symptomatic-drugs-for-cognitive-impairment-in-dementia-what-to-expect |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.dementiasplatform.uk/news-and-blogs/blog/symptomatic-drugs-for-cognitive-impairment-in-d... |
| Description | the UK Pharmacogenetics and Stratified Medicine Network |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presenter at the UK Pharmacogenetics and Stratified Medicine Network Workshop |
| Year(s) Of Engagement Activity | 2021 |
| Description | visit to local primary school |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | On 19th June, a team of Unit members went to St Ebbe's C. of E. (Aided) Primary School in central Oxford, where they visited Year 6 pupils and their teachers to help them learn more about science, researchers, and how the brain works to control memory and movement. Pupils were first given a brief introduction to the work of the Medical Research Council and the MRC Brain Network Dynamics Unit. Pupils, teachers and Unit members then engaged in a range of interactive discussions and hands-on activities that included looking at nerve cells under a microscope, reporting on observations by making model cells, measuring electrical activity from muscles to control a robotic claw, comparing the brains of different vertebrates, discovering different types of memories, and using a game version of a brain-machine interface. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.mrcbndu.ox.ac.uk/news/unit-goes-out-local-primary-school-mrc-festival-medical-research |