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MRC Toxicology Unit

Hodgkin Building, University of Leicester, PO Box 138, Lancaster Road, Leicester, LE1 9HN, United Kingdom (East Midlands)

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£1,072,752

May 10 - May 15

How do microRNAs regulate translation?

MRC award to MRC Toxicology Unit and Martin David Bushell

£1,261,994

Apr 07 - Sep 10

Cell death mechanisms in the peripheral immune system

MRC award to MRC Toxicology Unit and Michael Pinkoski

£11,657,140

Sep 08 - Feb 18

In vivo mechanisms of neurotoxicity

MRC award to MRC Toxicology Unit and Giovanna Mallucci

£3,994,234

Apr 02 - Feb 14

Genomic Instability in mature B-cells

MRC award to MRC Toxicology Unit and Martin Dyer

£7,121,435

Apr 92 - Aug 13

Molecular determinants of apoptosis

MRC award to MRC Toxicology Unit and Gerald Michael Cohen

£110,359

Jul 10 - Jul 11

Regulation of protein synthesis as a mechanism of nutritional programming and developmental origins of optimal health

BBSRC award to MRC Toxicology Unit and Anne Elizabeth Willis

£7,172,542

Apr 05 - Feb 18

Nitric oxide mediated toxicity in neurodegeneration and disease

MRC award to MRC Toxicology Unit and Ian Duncan Forsythe

£951,872

Apr 03 - Apr 08

Molecular & cellular functions of target proteins in toxic neuropathies

MRC award to MRC Toxicology Unit and Paul Glynn

£106,429

Jul 10 - Aug 11

Translation regulation elements in both the 5` and 3` untranslated region; how do they coexist?

BBSRC award to MRC Toxicology Unit and Martin David Bushell

£2,125,177

Apr 02 - Dec 09

Stress responses, oncogenic lesions and cell fate decisions

MRC award to MRC Toxicology Unit

£3,031,646

Apr 12 - Jul 18

Toxicity and the DNA-damage response.

MRC award to MRC Toxicology Unit and Michal Malewicz

£494,631

Nov 13 - Jul 16

GPR120: a G protein-coupled receptor with the potential to regulate insulin secretion and inflammation

BBSRC award to MRC Toxicology Unit and Andrew Tobin

£563,093

Feb 15 - Aug 16

Using a Designer Receptor Exclusively Activated by Designer Drug to define the role of short chain fatty acids in metabolic disease and inflammation

BBSRC award to MRC Toxicology Unit and Andrew Tobin

£112,890

Mar 14 - May 15

FLIP: A Flexible Interchange to Explore the Regulatory Role of Heme in the Cell

BBSRC award to University of Leicester and Emma Raven

£92,173

Oct 12 - Sep 16

Exploring signalling of mGlu 5 receptors in vitro and vivo

BBSRC award to MRC Toxicology Unit

£8,169,136

Jun 10 - Feb 18

The role of microRNAs in the cytotoxic response

MRC award to MRC Toxicology Unit and Martin David Bushell

£651,314

May 08 - Apr 09

Identification & characterisation of novel genes that regulate neurodegeneration and aging using Caenorhabditis elegans

MRC award to MRC Toxicology Unit and Daniele Bano

£4,251,634

Apr 12 - Aug 16

Physiological role of G-protein coupled receptors and models that investigate in vivo modes of action and toxicity

MRC award to MRC Toxicology Unit and Andrew Tobin

£142,557

Jul 10 - Jun 11

Enhancing global and mRNA specific translation for improved recombinant protein expression in in vitro cultured mammalian cells

BBSRC award to MRC Toxicology Unit and Anne Elizabeth Willis

£248,547

Oct 16 - Jul 19

Mechanisms of mitochondrial dysfunction during stress, toxicity and disease

MRC award to MRC Toxicology Unit and Kenneth Robert Pryde

£258,216

Jan 15 - Dec 17

The role of RNA-binding proteins in the nucleolar stress response

BBSRC award to MRC Toxicology Unit and Anne Elizabeth Willis

£1,400,316

Jul 13 - Jun 17

The Gain of function of mutant p53 in invasion and chemo-resistance

MRC award to MRC Toxicology Unit and Patricia Muller

£177,504

Jul 10 - May 11

Identification of mechanism(s) of miRNA- mediated repression of translation

BBSRC award to MRC Toxicology Unit and Martin David Bushell

£305,784

Jan 12 - Jan 15

Defining novel mechanisms of mRNA translational control upon cold-shock in mammalian cells

BBSRC award to MRC Toxicology Unit and Anne Elizabeth Willis

£605,420

Jul 11 - Jun 14

Investigation of the translational regulation of terminal oligo pyrimidine (TOP) containing mRNAs

BBSRC award to MRC Toxicology Unit and Anne Elizabeth Willis

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