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Dana-Farber Cancer Institute

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£386,000

Feb 09 - Dec 11

Exploitation of mouse models to validate protein kinases as drug targets

MRC award to MRC Protein Phosphorylation Unit and Dario Renato Alessi

£204,897

Oct 14 - Sep 17

SIP1 induced epithelial to mesenchymal transition (EMT) promotes metastasis and chemoresistance in colorectal cancer.

MRC award to University of Southampton and Rahul Sreekumar

£211,866

Apr 06 - Mar 09

Role of the Notch signalling pathway in acute myeloid leukaemia

MRC award to University College London and Marc Mansour

£1,456,162

Apr 13 - Mar 18

Characterisation of signal transduction pathways that restrict activation of the innate immune system to prevent inflammatory and autoimmune diseases

MRC award to University of Dundee and Philip Cohen

£2,935,822

Jan 14 - Jun 20

DECIPHer: Centre for the Development and Evaluation of Complex Interventions for Public Health Improvement

MRC award to Cardiff University and Laurence Anthony Moore

£1,561,134

Jul 07 - Jul 12

Functional characterisation of the major susceptibility locus (PSORS1) for cutaneous inflammation in psoriasis

MRC award to King's College London and Richard Charles Trembath

£1,219,034

Oct 98 - Jul 13

Clinical trials in testicular cancer

MRC award to MRC Clinical Trials Unit and Sally Stenning

£206,854

Aug 12 - Aug 14

Malaria, Productivity and Access to Treatment: Experimental Evidence from Nigeria

ESRC award to Michigan State University and Andrew Dillon

£1,485,260

Apr 06 - Jun 16

Large randomised trials and meta-analyses of breast cancer treatments

MRC award to Medical Research Council and Richard Peto

£206,908

Jun 06 - May 09

Exo-Net

MRC award to University of Liverpool and Christopher Mark Sanderson

£331,813

Jan 10 - Dec 11

ProMPT Renewal

MRC award to University of Cambridge and David Edgar Neal

£935,703

May 16 - Apr 21

Pathfinder: Defining interactions between the cytokine IL-22 and oncogenic KRAS as a new therapeutic target in colorectal cancer

MRC award to University of Oxford and Fiona Powrie

£709,959

Aug 10 - Apr 13

The signaling of phagosome biogenesis and its subversion by intracellular pathogens.

MRC award to MRC Protein Phosphorylation Unit and Matthias Trost

£2,302,000

May 13 - Mar 18

Understanding molecular mechanisms & consequences of TGF beta/BMP signal transduction pathways in cells & human diseases

MRC award to University of Dundee and Gopal Prasad Sapkota

£1,445,943

Apr 08 - Apr 13

Understanding molecular mechanisms & consequences of TGF beta/BMP signal transduction pathways in cells & human diseases

MRC award to MRC Protein Phosphorylation Unit and Gopal Prasad Sapkota

£3,141,000

May 13 - Mar 17

Proteomics to identify signalling in macrophage and phagosome biology

MRC award to University of Dundee and Matthias Trost

£1,450,107

Jan 11 - May 15

Generation of suppressive donor T cells to specifically control alloresponses after allogeneic stem cell transplantation

MRC award to Queen Mary, University of London and Jeffrey Keith Davies

£6,415,000

May 13 - Mar 18

Understanding signalling pathways mutated in inherited disorders

MRC award to University of Dundee and Dario Renato Alessi

£373,285

Jul 15 - Jul 18

A novel regulator of DNA double strand break repair fate with roles in immunity and oncogenesis

MRC award to University of Oxford and Jonathan Ross Chapman

£593,221

Sep 15 - Aug 18

Elucidating novel pluripotency signalling networks

MRC award to University of Dundee and Greg Findlay

£6,201,742

May 02 - Mar 12

Understanding the functions of LKB1 and other protein kinases mutated in inherited diseases

MRC award to MRC Protein Phosphorylation Unit and Dario Renato Alessi

£1,896,251

Apr 18 - Mar 23

TGFß and Wnt signalling during development and human disease

MRC award to University of Dundee and Gopal Prasad Sapkota

£323,689

Apr 16 - Mar 19

BAG-1: A novel strategy for targeting the androgen receptor splice variants in castrate resistant prostate cancer.

MRC award to Institute of Cancer Research and Adam Sharp

£254,088

Jan 08 - Jan 11

Characterisation of the LRRK2 protein kinase, mutated in inherited Parkinson s disease

MRC award to University of Dundee and Dario Renato Alessi

£1,393,000

Aug 13 - Mar 16

Improving Outcomes for Men with Prostate Cancer.

MRC award to University College London and Mahesh Parmar

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