Exploring the effects of nutrient deprivation on T cells and oncolytic adenoviruses, in order to create immune activators for tumour therapy
Lead Research Organisation:
UNIVERSITY OF OXFORD
Department Name: Oncology
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Organisations
People |
ORCID iD |
| Leonard Seymour (Primary Supervisor) | |
| Sally Frost (Student) |
Publications
Dyer A
(2019)
Antagonism of Glycolysis and Reductive Carboxylation of Glutamine Potentiates Activity of Oncolytic Adenoviruses in Cancer Cells.
in Cancer research
Scott EM
(2019)
Bi- and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples.
in Journal for immunotherapy of cancer
Dyer A
(2018)
Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference
in Cancer Gene Therapy
Scott EM
(2020)
Use of Liquid Patient Ascites Fluids as a Preclinical Model for Oncolytic Virus Activity.
in Methods in molecular biology (Clifton, N.J.)
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| MR/N013468/1 | 30/09/2016 | 29/09/2025 | |||
| 1813152 | Studentship | MR/N013468/1 | 30/09/2016 | 29/09/2020 | Sally Frost |
| Description | Biochemical Society General Travel Grant |
| Amount | £300 (GBP) |
| Funding ID | SALLYFROST GTG MAY2018 |
| Organisation | Biochemical Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 05/2018 |
| Description | Old Members' Trust Graduate Conference and Academic Travel Grant |
| Amount | £350 (GBP) |
| Organisation | University College Oxford |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 05/2018 |
| Description | UNIQ programme (Immunology session) |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Around 40 pupils from schools in the region came for the UNIQ 2019 programme at the University of Oxford. They are usually students who are from under-priveliged backgrounds and the aim of the programme is to get them interested in coming to university and in our subject. I presented a session on immunology that included in part a little about the research I am undertaking within this award. |
| Year(s) Of Engagement Activity | 2019 |