Developing Synchrotron Radiation Circular Dichroism (SRCD) Spectroscopy Methods and Applications for Structural Biology

Lead Research Organisation: Birkbeck College
Department Name: Biological Sciences

Abstract

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Publications

10 25 50
 
Description UK access to facilities at a time when there was no such facility in the UK
Exploitation Route no further access is available as the Brookhaven synchrotron has now been shut down
Sectors Education

 
Description enabled collaborations to develop synchrotron-based methods for spectroscopy
First Year Of Impact 2009
 
Title new software tools for CD analyses 
Description software and websites and you tube videos about new infrastructure tools developed for CD spectroscopy and structural biology 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? Yes  
Impact ongoing development of many new tools for bioinformatics and structural biology resources widespread usage of tools both in the UK and internationally 
 
Title The SP175 reference Data Set 
Description Data Set of Reference CD spectra of proteins deposited in the Protein Circular Dichroism Data Bank. protein circular dichoism data bank http://pcddb.cryst.bbk.ac.uk/home.php 
Type Of Material Database/Collection of data 
Year Produced 2009 
Provided To Others? No  
Impact No actual impacts realised to date 
URL http://pcddb.cryst.bbk.ac.uk/home.php
 
Description Collaboration with Brookhaven National Lab (Dr. J.Sutherland) 
Organisation Brookhaven National Laboratory
Department National Synchrotron Light Source
Country United States 
Sector Public 
PI Contribution Enabled us to access the Brookhaven SRCD beamline when there was none in the UK
Collaborator Contribution provided access to instrumentation
Impact students and postdocs had access to SRCD beamline when there was none in the UK. the Brookhaven beamline has now been shut down and our collaborator has retired
Start Year 2009
 
Description Running training workshops for students, postdocs and industrial scientists on CD spectroscopy 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Teaching Lectures and Practicals in multi-day workshops to provide new skills training and ideas and information for researchers both nationally and internationally
Year(s) Of Engagement Activity Pre-2006,2006,2007,2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018
 
Description annual talks for the public 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact UCL Science Centre Friday Evening Discourses and Birkbeck SET Talks for the Public talks on science for the public (5th, 6th form, and public) annually and lecture/tour at the Wellcome Collection talks

no actual impacts realised to date
Year(s) Of Engagement Activity 2006,2007,2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020
 
Description international advisory boad (germany) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact international advisory board (Germany)
Year(s) Of Engagement Activity 2011,2012,2013,2014,2015,2016,2017,2018
 
Description international advisory board (australia) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact international advisory board for scientific centre of excellence (australia)
Year(s) Of Engagement Activity 2008,2009,2010,2011,2012,2013,2014,2015,2016,2017