China partnering: exploiting actinobacteria from extreme environments

Lead Research Organisation: Swansea University
Department Name: Institute of Life Science Medical School

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

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Zhang B (2016) Streptomyces lacrimifluminis sp. nov., a novel actinobacterium that produces antibacterial compounds, isolated from soil. in International journal of systematic and evolutionary microbiology

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Zhang B (2019) sp. nov., isolated from soil of Qinghai-Tibet Plateau. in International journal of systematic and evolutionary microbiology

 
Description Several new antibiotic-producing soil bacteria have been isolated from extreme environments in NW China. Antibiotics are currently being purified for structural and activity analyses.
Exploitation Route Any novel antibiotics with promising activities could be taken further by the pharmaceutical industry for eventual medical use.
Sectors Pharmaceuticals and Medical Biotechnology

 
Description Swansea-Lanzhou research collaboration 
Organisation Chinese Academy of Sciences
Department Northwest Institute of Eco-Environment and Resources
Country China 
Sector Academic/University 
PI Contribution Following the end of the China partnering award, the research collaboration has continued. Prof Dyson visited Lanzhou in spring 2017 to write a paper that was submitted and accepted for publication by PLoS Genetics. Additional collaborative research is currently underway.
Collaborator Contribution They contributed the lab-based research and funding.
Impact See list of publications.
Start Year 2014
 
Description Antimicrobial resistance sandpit event, Cardiff 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Talk: Isolation of new antibiotic producing Streptomyces species & genetic manipulation for expression
Year(s) Of Engagement Activity 2017