Combing biophysical and 'omics methods for understanding the basis of blood clotting and haemostasis, and how to modify it

Lead Research Organisation: University of Manchester
Department Name: Chemistry

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

10 25 50

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Kell DB (2018) No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases. in Biological reviews of the Cambridge Philosophical Society

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Koperdanova M (2015) Interpreting raised serum ferritin levels. in BMJ (Clinical research ed.)

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Olsen I (2020) Is Porphyromonas gingivalis involved in Parkinson's disease? in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

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Potgieter M (2015) The dormant blood microbiome in chronic, inflammatory diseases. in FEMS microbiology reviews

 
Description Discovery of amyloid formation by clotting blood. Absolutely humungous discovery.

Novel methods for analysing blood in control and unhealthy individuals. In particular, we discovered that blood clots into an unusual form, known as an amyloid form, and this has huge implications.
Exploitation Route Novel diagnostics.
Sectors Digital/Communication/Information Technologies (including Software),Education,Healthcare,Pharmaceuticals and Medical Biotechnology