US Partnering Award - Carbohydrate Sequencing Consortium
Lead Research Organisation:
The University of Manchester
Department Name: Chemistry
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Bell E
(2021)
Biocatalysis
in Nature Reviews Methods Primers
Bulmer G
(2021)
A promiscuous glycosyltransferase generates poly-ß-1,4-glucan derivatives that facilitate mass spectrometry-based detection of cellulolytic enzymes
in Organic & Biomolecular Chemistry
Cioce A
(2022)
Cell-specific bioorthogonal tagging of glycoproteins.
in Nature communications
Cosgrove S
(2019)
Biocatalytic Oxidation in Continuous Flow for the Generation of Carbohydrate Dialdehydes
in ACS Catalysis
Ford GJ
(2020)
Synthesis of protected 3-aminopiperidine and 3-aminoazepane derivatives using enzyme cascades.
in Chemical communications (Cambridge, England)
Gray CJ
(2017)
Bottom-Up Elucidation of Glycosidic Bond Stereochemistry.
in Analytical chemistry
Gray CJ
(2019)
Advancing Solutions to the Carbohydrate Sequencing Challenge.
in Journal of the American Chemical Society
Gray CJ
(2020)
Mass spectrometry hybridized with gas-phase InfraRed spectroscopy for glycan sequencing.
in Current opinion in structural biology
Keenan T
(2020)
Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.
in Cell chemical biology
Kempa EE
(2021)
Rapid Screening of Diverse Biotransformations for Enzyme Evolution.
in JACS Au
Mattey A
(2019)
Selective Oxidation of N -Glycolylneuraminic Acid Using an Engineered Galactose Oxidase Variant
in ACS Catalysis
Mattey AP
(2021)
Development of Continuous Flow Systems to Access Secondary Amines Through Previously Incompatible Biocatalytic Cascades*.
in Angewandte Chemie (International ed. in English)
Mattey AP
(2020)
Natural heterogeneous catalysis with immobilised oxidase biocatalysts.
in RSC advances
Mattey AP
(2021)
Development of Continuous Flow Systems to Access Secondary Amines Through Previously Incompatible Biocatalytic Cascades.
in Angewandte Chemie (Weinheim an der Bergstrasse, Germany)
Pallister E
(2020)
Enzyme promiscuity of carbohydrate active enzymes and their applications in biocatalysis.
in Current opinion in structural biology
Valverde P
(2020)
Chemoenzymatic synthesis of 3-deoxy-3-fluoro-l-fucose and its enzymatic incorporation into glycoconjugates.
in Chemical communications (Cambridge, England)
Weise N
(2020)
Bi-enzymatic Conversion of Cinnamic Acids to 2-Arylethylamines
in ChemCatChem
| Description | Too early to comment, |
| Exploitation Route | Too early to say, grant in early stages |
| Sectors | Agriculture Food and Drink Chemicals Healthcare Manufacturing including Industrial Biotechology Pharmaceuticals and Medical Biotechnology |
| Title | CCDC 1922810: Experimental Crystal Structure Determination |
| Description | Related Article: Pablo Valverde, Jean-Baptiste Vendeville, Kristian Hollingsworth, Ashley P. Mattey, Tessa Keenan, Harriet Chidwick, Helene Ledru, Kler Huonnic, Kun Huang, Mark E. Light, Nicholas Turner, Jesús Jiménez-Barbero, M. Carmen Galan, Martin A. Fascione, Sabine Flitsch, W. Bruce Turnbull, Bruno Linclau|2020|Chem.Commun.|56|6408|doi:10.1039/D0CC02209H |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc22jv4m&sid=DataCite |
| Description | Manchester Institute of Biotechnology Open Day, 8th November 2013 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | The MIB Open Day was specifically aimed at A-Level students nationally. The day focused on hands-on experiments and lectures to promote working at the interface between chemistry and biology to solve problems with a biological 'green' solution and encourage science students to pick applied science subjects. The feedback was very positive with pupils reporting that they now realized there were a lot more options for further study and jobs than they previously knew about. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Science Spectacular, Manchester Museum 2nd November 2014 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | The Science Spectacular is aimed at families to promote sciences as fun and useful. The feedback from individuals questioned were all positive, reporting changes in their opinions and behaviour and more pupils expressing an interest in studying science further. |
| Year(s) Of Engagement Activity | 2014 |
| Description | The Science Spectacular, Manchester Museum, 2nd November 2013 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | The Royal Society Summer Science Exhibition proved so popular that we were asked to be part of The Science Spectacular, 2nd November 2013 at The Manchester Museum http://www.manchestersciencefestival.com/whatson/science-spectacular. The Science Spectacular was aimed primarily at young children and families to encourage children to enjoy science. The feedback from parents was very positive. |
| Year(s) Of Engagement Activity | 2013 |
| URL | http://www.manchestersciencefestival.com/whatson/science-spectacular |