Glycoenzymes for Bioindustries
Lead Research Organisation:
University of Manchester
Department Name: Chemistry
Abstract
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People |
ORCID iD |
| Rob Field (Principal Investigator) |
Publications
Bulmer GS
(2021)
Recent advances in enzymatic synthesis of ß-glucan and cellulose.
in Carbohydrate research
De Andrade P
(2021)
Chemoenzymatic Synthesis of Fluorinated Cellodextrins Identifies a New Allomorph for Cellulose-Like Materials*.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Gabrielli V
(2021)
Molecular Recognition of Natural and Non-Natural Substrates by Cellodextrin Phosphorylase from Ruminiclostridium Thermocellum Investigated by NMR Spectroscopy.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Wangpaiboon K
(2020)
Characterisation of insoluble a-1,3-/a-1,6 mixed linkage glucan produced in addition to soluble a-1,6-linked dextran by glucansucrase (DEX-N) from Leuconostoc citreum ABK-1.
in International journal of biological macromolecules
| Description | New methods for the enzymatic synthesis of a range of sugar derivatives - glycosides, sugar nucleotides, glycopolymers. |
| Exploitation Route | Ongoing development of links to academic collaborators (UK and Thailand, in particular) and to industry (Mologic, DSM, Iceni Dx) BBSRC Prosperity Partnership bid with Unilever, led by UCL, is currently in preparation. This bid makes use of the technology and connectivity provided by the original grant. |
| Sectors | Agriculture, Food and Drink,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
| Description | Human milk oligosaccharides |
| Organisation | DSM |
| Department | DSM Biotechnology Centre |
| Country | Netherlands |
| Sector | Private |
| PI Contribution | Know-how and expertise for the chemical modification of carbohydrates. |
| Collaborator Contribution | Provision of 100mg-1g quantities of 6 human milk oligosaccharides. |
| Impact | Only just started |
| Start Year | 2021 |
| Description | Sugar nucleotides |
| Organisation | Keele University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Enzymatic synthsesis |
| Collaborator Contribution | Chemical synthesis - methods development and target synthesis. |
| Impact | New integrated chemical and enzymatic methods for sugar nucleotide synthesis |
| Start Year | 2020 |