United States-UK partnering award:Co-infection and resistance (CORE)

Lead Research Organisation: University of Glasgow
Department Name: College of Medical, Veterinary &Life Sci

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

10 25 50
 
Description We had our first joint meeting at which all members of the Consortium were present in February 2017. In addition we were able to invite relevant individuals from the UK institutes (Universities of Liverpool and Glasgow) to participate in the meeting. The topic of the meeting was Co-infections and resistance and we had some excellent talks in this area. One outcome of this first meeting was a new collaboration between University of Glasgow and the University of Georgia, Athens, USA.

We had our second joint meeting in May 2018 at the University of Glasgow Field Station at Loch Lomond. The topics was Refugia and its application in anthelmintic resistance. Again we invited several key colleagues who are not part of the CORE grant. This was a very successfull meeting from which a small BBSRC travel award was funded and two large collaborative applications for NSF-BBSRC funding emerged. In addition, we have written a review of Refugia and its role in mitigating anthelmintic resistance.
Exploitation Route Our common interests have already spawned one new scientific collaboration and we have obtained a travel grant to further our objectives and two large collaborative grants directly stemming from CORE funding have ben submitted.
Sectors Agriculture, Food and Drink

 
Description BBSRC:Research Grant United States-UK partnering award
Amount £47,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 05/2016 
End 04/2018
 
Description Travel Grant
Amount £1,045 (GBP)
Funding ID BB/S013725/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2018 
End 12/2018
 
Description iBAHCM internal funding
Amount £3,000 (GBP)
Organisation University of Glasgow 
Sector Academic/University
Country United Kingdom
Start 03/2017 
End 08/2017
 
Description Serengeti worms 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Dr Tom Morrison, an ecologist at the University of Glasgow, was invited to our first IPA meeting in Liverpool in 2017. He met Dr Vanessa Ezenwa there and they formed a collaboration based around their common interest in helminths that parasitise wildlife in Africa. They are interested in whether wild mammals (wildebeest) share the same parasitic helminths as domestic animals (cattle), whether migratory and resident wildebeest populations are equally parasitised and whether there is any evidence that migrating animals may facilitate the spread of drugs resistant worms.
Collaborator Contribution Dr Grant Hopcraft applied as PI to the SHEFC GCRF funding call and was successful in obtaining funding, a small amount of which was allocated to Dr Morrison for the collection of parasite samples from migrating and resident wildebeest in the Serengeti. In addition, Dr Morrison successfully applied for funding from the University of Glasgow to enable additional sample collection.
Impact Multidisciplnary
Start Year 2017
 
Description A talk or presentation - Short talk at CORE meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A short presentation on research carried out (relating primarily to a faecal egg count reduction test and species diversity on a UK farm) was presented at a small meeting in Liverpool. Those present were gathered to discuss 'Co-infections and Resistance'.
Year(s) Of Engagement Activity 2017
 
Description CORE meeting presentation 2017 by Vanessa Ezenwa: Conflicting effects of anthelmintic treatment and natural host resistance on the host response to bovine TB infection in wildlife 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at the first joint meeting of CORE. Outcome was a new collaboration between Dr Ezenwa (University of Athens, Georgia) and Dr Morrison (University of Glasgow)
Year(s) Of Engagement Activity 2017
 
Description CORE meeting presentation: The stuff of life for a wood mouse? ?Food, sex, worms, and ticks 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presntation of my groups' work. Participation in discussions with the other CORE partners to set working theme priorities and identifying future collaboration and funding opportunities.
Year(s) Of Engagement Activity 2017
 
Description Invited talk (keynote) at Anthelmintics III Meeting in Florida 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Invited talk on the use of a genetic cross to study anthelmintic resistance in a parasitic nematode of sheep, attended by roughly 100 participants from around the world, followed by good discussion regarding preliminary findings.
Year(s) Of Engagement Activity 2018
 
Description Presentation to CORE group 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact Research talk to other members of the CORE research team, on the combination of empirical data and theory to understand occurrence and impact of coinfecting parasites on parasite dynamics and host health.
Year(s) Of Engagement Activity 2017
 
Description Short talk at conference Anthelmintic Resistance III 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A short talk was given at the international conference 'Anthelmintic Reisistance III' in Florida. Those present included researchers, postgraduate students and industry professionals. The talk described preliminary results from recent work using genome wide sequencing to identify genomic regions of selection following ivermectin treatment in a UK field population of T. circumcincta.
Year(s) Of Engagement Activity 2018
 
Description Talk at CORE meeting 2017 by Dr Robin Flynn: Mechanisms of Fasciola-induced immunosuppression; lessons from TB co-infection 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dr Flynn presented his work on co-infections at the first meeting of the CORE group in Liverpool in 2017
Year(s) Of Engagement Activity 2017
 
Description Workshops for BBSRC Resistance highlight call 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact I presented at two workshops to accompany the BBSRC Highlight call in Resistance in Agriculture
Year(s) Of Engagement Activity 2016