Canada: Functional annotation of the Atlantic salmon genome, translation to improved health and performance for Aquaculture
Lead Research Organisation:
University of Aberdeen
Department Name: Inst of Biological and Environmental Sci
Abstract
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Organisations
- University of Aberdeen (Lead Research Organisation)
- UNIVERSITY OF EDINBURGH (Collaboration)
- University of Victoria (Collaboration, Project Partner)
- Memorial University of Newfoundland (Collaboration, Project Partner)
- French National Institute of Agricultural Research (Collaboration)
- Simon Fraser University (Project Partner)
Publications
Houston RD
(2020)
Harnessing genomics to fast-track genetic improvement in aquaculture.
in Nature reviews. Genetics
Houston RD
(2019)
Atlantic salmon (Salmo salar L.) genetics in the 21st century: taking leaps forward in aquaculture and biological understanding.
in Animal genetics
Król E
(2020)
Integration of Transcriptome, Gross Morphology and Histopathology in the Gill of Sea Farmed Atlantic Salmon (Salmo salar): Lessons From Multi-Site Sampling
in Frontiers in Genetics
| Description | Several workshops have been held, during November 2018 the second workshop was held in Aberdeen, 16 experts from UK and Canada were joined by two further researchers from INRA, France. The outcomes of the workshop included applying for the next international conference on salmonid biology to be held in Scotland. Also an application being generated for Horizon 2020 was further discussed prior to submission of an application. During 2019 an international conference was held in Scotland. The 4th International Conference on Integrative Salmonid Biology 17- 20th November 2019. This conference was organised by the partners on this BBSRC partnering award and many of the Canadian partners also came and contributed to the meeting. >200 international scientists attended the meeting. A final meeting was to be held for the partnering team during autumn 2020, but due to COVID this final meeting was cancelled. On going interactions have continued with much closer communication between the research groups involved. |
| Exploitation Route | The outputs from the Canada / UK workshops under the partnering award have meant the next international meeting for salmonid genomics will be held in the UK. This is being coordinated by Dr MacQueen, Prof Houston and Prof Martin, all partners on the award. The conference is the 4th International Conference on Integrative Salmonid Biology (ICISB), 17-20th November 2019. The knowledge gained form this partnership and scientists meeting at the ICISB conference have feed into new grant proposals. Successful grant have been awarded to the partners from both BBSRC and EU 2020 |
| Sectors | Agriculture Food and Drink Environment Manufacturing including Industrial Biotechology |
| Description | The international partnering award between Canada and UK salmonid genomics researchers has led to new interactions with indutrial sector. A main offshoot from the project has been the next international conference on salmonid biology "International conference on integrative salmonid biology" was organised by the UK grant holders Martin, Macqueen and Houston in Edinburgh 17-20 November 2019. Thiis was a highly successful meeting with global attanedance for those working on wild and farmed salmonids with interests in genomics. This conference will be an opportunity to highlight the UK research in salmon genomics. There was also good attendance from the salmonid aquaculture industry and wild fish interests. A final workshop was planned for autumn 2020, but it was not possible to have this in UK due to COVID travel restrictions. The groiups howevere are still in active contact. The outputs from the partnering award will be followed up by a further "International conference on integrative salmonid biology" during Spring 2024 most likly in USA. Other outcome were the Co Editing of a special isue in "Frontiers of Immunology" of transcriptomics and mucosal health in fish. |
| Sector | Agriculture, Food and Drink,Environment |
| Impact Types | Societal |
| Description | AQUA-FAANG Horizon 2020 Framework Programme |
| Amount | € 6,000,000 (EUR) |
| Funding ID | 817923 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 04/2019 |
| End | 04/2023 |
| Description | Improving resistance to infectious salmon anaemia using genome editing: Novel approaches to tackling viral disease in aquaculture |
| Amount | £205,540 (GBP) |
| Funding ID | BB/R008973/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2022 |
| Description | Investigating the potential of nutritional programming to improve the utilisation of sustainable feeds in aquaculture |
| Amount | £673,766 (GBP) |
| Funding ID | BB/R018812/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2019 |
| End | 12/2022 |
| Description | Novel Omega-3 Sources in Feeds and Impacts on Salmon Health |
| Amount | £726,052 (GBP) |
| Funding ID | BB/S005919/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2019 |
| End | 12/2024 |
| Description | ROBUST-SMOLT Impact of early life history in freshwater Recirculation Aquaculture Systems on A. salmon robustness and susceptibility to disease at sea |
| Amount | £195,126 (GBP) |
| Funding ID | BB/S004270/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2019 |
| End | 12/2022 |
| Description | INRA, Fish Virology and Immunology. Dr Collet and Dr Boudinot |
| Organisation | French National Institute of Agricultural Research |
| Department | INRA Versailles |
| Country | France |
| Sector | Academic/University |
| PI Contribution | The Lab in INRA is also working on Gene editing in fish cell lines. |
| Collaborator Contribution | Exchange of knowledge and approaches for gene editing |
| Impact | None as yet |
| Start Year | 2017 |
| Description | Prof Dan Macqueen |
| Organisation | University of Edinburgh |
| Department | The Roslin Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaborate on a number of EU and UK funded projects |
| Collaborator Contribution | Collaborate on a number of EU and UK funded projects |
| Impact | Partners on BBSRC and EU H2020 projects. |
| Start Year | 2018 |
| Description | Prof Matt Rise |
| Organisation | Memorial University of Newfoundland |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | International partner on Salmonid Genomics. Hosted event for the UK Canada partnering grant. |
| Collaborator Contribution | International partner on Salmonid Genomics. Hosted event for the UK Canada partnering grant. |
| Impact | A Special issue in Fronters in Immunology: "New Insights into Mucosal-Associated Lymphoid Tissues in Fish". has been initiated between with Memebrs of dr Rise's team and Aberdeen as Guest editors. |
| Start Year | 2018 |
| Description | Salmon genomics |
| Organisation | University of Victoria |
| Department | Department of Biology |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Prof Ben Koop is a leading fish genomics expert and is a partner on the BBSRC / Canada partnering award. |
| Collaborator Contribution | Significant interactions in relation to transcriptomics and genomics in salmon |
| Impact | The outputs have been a working white paper in BMC Genomics highlighting the next stages of functional annotation of the salmonid genomes. |
| Start Year | 2017 |
| Description | Dan Macqueen, BBSRC UK,Canada partnering award workshop 1: research relevant to FAASG, live projects an future plans. Victoria, Canada 16&17 November 2017 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Presentation to fish Genomics workshop relating to functional annotation of salmonid genomes |
| Year(s) Of Engagement Activity | 2017 |
| Description | Macqueen DJ. 'Linking evolution and function through genomes - Fishing for insights'. Roslin Institute, University of Edinburgh. Hosted by Prof. Ross Houston Aug 2017. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited seminar to University of Edinburgh, Roslin Institute |
| Year(s) Of Engagement Activity | 2017 |
| Description | Sam Martin, BBSRC UK,Canada partnering award workshop 1: Genome annotation and immune function. Victoria, Canada 16&17 November 2017 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation to BBSRC_Canada partnering award workshop |
| Year(s) Of Engagement Activity | 2017 |
| Description | Workshop for UK and Canada salmon genome researchers, StJohn's Newfoundland, Canada 26 and 27th August 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Study participants or study members |
| Results and Impact | This workshop was the 3rd in a series of Bilateral meetings between UK researchers and Canadian researchers examining the use of genomics for aquaculture of Atlantic salmon. The meeting was hosted by Memorial university, Canada, with a special emphasis on "core assays being developed through FAASG "Robust fish, epigenomics and the effects of early life experience on later outcomes for salmonid health". The meeting was attended by 20 active researchers including postgraduate, postdoctoral and senior academics. Representatives from Canadian funding agencies, Genome Atlantic were present for part of the meeting. |
| Year(s) Of Engagement Activity | 2019 |