UK-China partnership: Chromosomal Instability aiding Genetic Variants (CIVa) linked to human ageing
Lead Research Organisation:
Queen Mary University of London
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Song X
(2021)
Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation.
in Nature communications
Efstathiou C
(2021)
Electrically tunable lenses - eliminating mechanical axial movements during high-speed 3D live imaging.
in Journal of cell science
Dang D
(2023)
Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamics.
in The Journal of cell biology
| Description | How are mono-oriented chromosome-microtubule attachments protected to prevent errors in mitosis and associated cellular ageing? |
| Amount | £403,927 (GBP) |
| Funding ID | BB/W002698/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2021 |
| End | 09/2024 |
| Description | How are mono-oriented chromosome-microtubule attachments protected to prevent errors in mitosis and associated cellular ageing? |
| Organisation | Queen Mary University of London |
| Department | School of Biological and Chemical Science QMUL |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Conducted Super-resolution imaging; trained personnel on timelapse recording; and secured funding to expand the work. |
| Collaborator Contribution | Comparison across model systems; modelling of structures |
| Impact | Funding: https://gtr.ukri.org/projects?ref=BB%2FW002698%2F1 |
| Start Year | 2022 |
| Description | Online seminars with Beijing Agricultural university |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | 30 researchers attended an online meeting to discuss human variants. |
| Year(s) Of Engagement Activity | 2009,2021 |