MAb Adsorption and Solution Stability Workshop 2022
Lead Research Organisation:
The University of Manchester
Department Name: Physics and Astronomy
Abstract
People |
ORCID iD |
| Jian Lu (Principal Investigator) |
| Description | Understanding the relevance of antibody adsorption to the stability of antibody therapeutics Adsorption of antibodies to different interfaces can lead to different fates; some interfacial adsorption, e.g., very hydrophilic solid/water interface, may not cause large structural deformation or unfolding. In contrast, adsorption to hydrophobic surfaces such as hydrophobic hydrocarbon chain (SAMs) may lead to unfolding and aggregation. Building a network of industrial and academic partners who share interests and skills in the topic. This was evidenced from a BBSRC sponsored antibody adsorption and stability workshop, held during Dec 2022, with some 20 international speakers and 50 attendants, all invited. |
| Exploitation Route | Through conference talks and seminars and publications. |
| Sectors | Healthcare Manufacturing including Industrial Biotechology Pharmaceuticals and Medical Biotechnology |
| URL | https://scholar.google.com/citations?user=n5SCez8AAAAJ&hl=en |
| Description | Industrial-academic network to communicate knowledge and share skills in understanding antibody stability and implications. |
| First Year Of Impact | 2022 |
| Sector | Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
| Impact Types | Societal Economic |