Pig genome annotation and analysis

Lead Research Organisation: Roslin Institute
Department Name: Genetics and Genomics

Abstract

We propose to provide state of the art analysis and annotation of the pig genome sequence being generated by the International Pig Genome Sequencing Project. We will make the annotated genome sequence accessible on the Web through the Ensembl site at http://www.ensembl.org . The pig genome is the entire DNA sequence of the pig which defines all the biological molecules that make up a pig. By acquiring, managing and annotating the pig genome sequence one accelerates research for both pig biology and for mammalian biology. Impact on pig biology: Because of the extensive selective breeding which has occurred during domestication, there are a considerable number of breed or line-specific features, from fat/muscle ratios, litter size to skin colour. These features can be mapped genetically into broad regions of the genome, but the final identification of the genes responsible and the causal genetic variation is very complex. The availability of a well-annotated pig genome sequence with links to other data sources, especially those on phenotypes such as growth, carcass composition or responses to infectious disease would provide a dramatic boost to the identification of these causative genes. Impact on Human biology: The pig genome, as with all mammals has diverged relatively recently from the human lineage. This allows us to look for the effect of evolution in the genome. In comparing genome sequences both the similarities and the differences are informative. Sequences that are conserved across multiple species probably represent essential coding or regulatory sequences. Sequences that differ across species and show evidence of rapid evolutionary change can be important determinants of species survival, including reproductive fitness and the ability to respond to infectious disease. Thus, the comparative genome sequence analyses that we will perform will help us understand mammalian - and hence human - biology, including disease processes.

Technical Summary

The genome represents a complete description of an organism. However, to understand the functioning of the genes and regulatory elements, and to design sensible molecular biological experiments to test hypotheses, the genome sequence must be related to the extant functional data for that organism. We propose to annotate and analyse the sequence being generated by the International Pig Genome Sequencing Project. We will use the well established Ensembl system as the main tool for storage, management and dissemination of pig genome data. Pig genome sequencing is currently funded to 3-4x coverage from mapped clones, with two chromosomes at higher coverage. Experience from other low coverage genomes, such as cow, rabbit and armadillo is that this coverage will minimally provide an effective representation of exons, which can then be assembled into genes using a guide genome. By definition this approach cannot resolve lineage specific expansions in the pig genome. However, with this more clone based strategy there will be new opportunities for combining both assembly and annotation strategies to leverage more information out of a 3x assembly. We will integrate the pig genome sequence with diverse pre-existing data sets, including SNPs, ESTs and quantitative trait loci (QTL). We will integrate the sequence with maps (genetic, physical) and physical resources (clones, microarrays) providing a seamless route for interrogation and development of experimentation tools. Finally computational approaches, integrating the above resources and also leveraging the comparative genomics potential in the mammalian clade will be used to analyse and present the genome in a user friendly format. An annotated pig genome sequence will dramatically accelerate research on the pig as an important animal for agriculture and human biology. Our aim is to make the pig genome sequence maximally useful by delivering an annotated sequence of the highest quality in a user friendly manner.

Organisations

Publications

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Archibald, A (2010) Annotation of the pig genome in Plant & Animal Genomes XVIII Conference

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Archibald, A (2009) Assembly and annotation of the pig genome in Pig Genome III Conference: A celebration for completing the pig genome sequence. Swine Genome Sequencing Consortium and PigNet Genome Conference.

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Dawson HD (2013) Structural and functional annotation of the porcine immunome. in BMC genomics

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Groenen MA (2012) Analyses of pig genomes provide insight into porcine demography and evolution. in Nature

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Groenen, M (2010) The porcine HapMap project: Genome-wide assessment of nucleotide diversity, haplotype diversity and footprints of selection in the pig in Plant & Animal Genomes XVIII Conference

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Humphray SJ (2007) A high utility integrated map of the pig genome. in Genome biology

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Jann OC (2009) Comparative genomics of Toll-like receptor signalling in five species. in BMC genomics

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Ramos AM (2009) Design of a high density SNP genotyping assay in the pig using SNPs identified and characterized by next generation sequencing technology. in PloS one

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Tang, H (2010) Structural and copy number variation in the pig genome in Plant & Animal Genomes XVIII Conference

 
Description 1. Assembly the low coverage pig genome sequence to provide an effective platform for annotation and research

The current assembly (Sscrofa9) was generated from a data freeze in Apr'09 by the Sanger partner and has proved to be an effective platform for annotation and research. A new assembly (Sscrofa10) which will form the basis of the pig genome sequence paper will integrate Illumina short read data (~30x coverage) to improve contiguity and coverage - due Sept 2010.



2. Annotate the pig genome sequence to provide high quality protein coding gene set and high quality RNA gene set

In addition to the annotation of the SScrofa9 assembly using the Ensembl automatic gene prediction pipelines manual annotation has also been undertaken. Sets of both protein coding and non coding RNA genes have been generated. The manual annotation is accessible as a DAS track.



3. Compute comparative genomics alignments between pig and the major mammals (human, mouse, cow) and other key vertebrates

See reports of Ensembl partners at Sanger and EBI.



4. Associate pig specific resources, including QTLs, microarray probes, SNPs and clones with both the genome and genes

Cross references to the Affymetrix Porcine micro array have been generated. SNPs from dbSNP have been remapped from the NCBI Sus scrofa build 1.1 to make them available.

The sequences of the SNPs on the Illumina Porcine 60K SNP chip have been mapped to the Sscrofa9 assembly and are accessible as a DAS track.



5. Provide a user friendly web site of this information

While the sequencing was in progress, Ensembl Pre sites containing alignments of proteins from other species were made available. Once the gene set was completed on the Sscrofa9 assembly, pig was made available in the main Ensembl site (http://www.ensembl.org/Sus_scrofa). This provides detailed genomic location, gene, comparative genomic and variation displays of the data available for pig.

Training workshops (2 in the UK at Hinxton and 1 in the US) were organized for manual annotation using the Otterlace system.
Sectors Agriculture, Food and Drink
URL http://www.ensembl.org/Sus_scrofa/Info/Index
 
Description Ensembl - farm animal 
Organisation EMBL European Bioinformatics Institute (EMBL - EBI)
Country United Kingdom 
Sector Academic/University 
PI Contribution The Roslin Institute partner(s) in this three-centre collaboration concerned with maintaining the currency of the annotation of farmed animal genome bring extensive links to the farm animal research community, and especially to research groups engaged in genetics and genomics research on farmed animal species. The Roslin Institute partner(s) are also major generators of genomics data for these farmed animal species.
Collaborator Contribution The Ensembl genome database and associated tools were developed by a cross-institute team (EMBL-EBI and Sanger). This EBI-Sanger Ensembl team have developed the database and software tools which allow the effective semi-automated annotation of reference genome sequences.
Impact This collaboration has annotated the reference genome sequences for chicken, cow, pig, sheep, dog, horse, turkey, duck
 
Description Ensembl - farm animal 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution The Roslin Institute partner(s) in this three-centre collaboration concerned with maintaining the currency of the annotation of farmed animal genome bring extensive links to the farm animal research community, and especially to research groups engaged in genetics and genomics research on farmed animal species. The Roslin Institute partner(s) are also major generators of genomics data for these farmed animal species.
Collaborator Contribution The Ensembl genome database and associated tools were developed by a cross-institute team (EMBL-EBI and Sanger). This EBI-Sanger Ensembl team have developed the database and software tools which allow the effective semi-automated annotation of reference genome sequences.
Impact This collaboration has annotated the reference genome sequences for chicken, cow, pig, sheep, dog, horse, turkey, duck
 
Description International Swine Genome Sequencing Consortium 
Organisation Aarhus University Hospital
Country Denmark 
Sector Hospitals 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Aberystwyth University
Country United Kingdom 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Beijing Genomics Institute
Country China 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Catalan Institution for Research and Advanced Studies (ICREA)
Department ICREA Centre for Research in Agricultural Genomics (CRAG)
Country Spain 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Durham University
Country United Kingdom 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation EMBL European Bioinformatics Institute (EMBL - EBI)
Country United Kingdom 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Earlham Institute
Country United Kingdom 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Eversole Associates
Country United States 
Sector Private 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation French National Institute of Agricultural Research
Department GABI: Animal Genetics and Integrative Biology unit
Country France 
Sector Private 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation French National Institute of Agricultural Research
Department Physiology of Reproduction and Behavior
Country France 
Sector Private 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation French National Institute of Agricultural Research
Country France 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Genetic Information Research Institute
Country United States 
Sector Charity/Non Profit 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Glasgow Caledonian University
Country United Kingdom 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Huazhong Agricultural University
Country China 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Iowa State University
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Jeju National University
Country Korea, Republic of 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Kansas State University
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Konkuk University
Country Korea, Republic of 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Konkuk University
Country Korea, Republic of 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Korea Research Institute of Bioscience and Biotechnology (KRIBB)
Country Korea, Republic of 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation National Health and Medical Research Council
Country Australia 
Sector Public 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation National Institute of Agrobiological Science, Japan
Country Japan 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation National Institute of Animal Science, Korea
Country Korea, Republic of 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation National Institute of Animal Science, Korea
Country Korea, Republic of 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Parco Tecnologico Padano
Country Italy 
Sector Private 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Penn State University
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Science for Life Laboratory
Country Sweden 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Seoul National University
Country Korea, Republic of 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation U.S. Department of Agriculture USDA
Department Beltsville Agricultural Research Center
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation U.S. Department of Agriculture USDA
Department U.S. Meat Animal Research Center
Country United States 
Sector Public 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation U.S. Department of Agriculture USDA
Country United States 
Sector Public 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University College London
Department Division of Infection and Immunity
Country United Kingdom 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of California, Berkeley
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of California, Davis
Department UC Davis Genome Cente
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Copenhagen
Department Department of Basic Animal and Veterinary Sciences (IBHV)
Country Denmark 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Illinois at Urbana-Champaign
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Illinois at Urbana-Champaign
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Illinois at Urbana-Champaign
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Illinois at Urbana-Champaign
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Illinois at Urbana-Champaign
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Kent
Country United Kingdom 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Leipzig
Country Germany 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation University of Minnesota
Country United States 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Uppsala University
Country Sweden 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Uppsala University
Country Sweden 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.
 
Description International Swine Genome Sequencing Consortium 
Organisation Wageningen University & Research
Country Netherlands 
Sector Academic/University 
PI Contribution The Roslin Institute partner in the Swine Genome Sequencing Consortium contributed to the leadership of the pig genome sequencing project, coordination of analysis and annotation and writing the genome paper. On-going commitments to the SGSC include efforts to improve the reference genome sequence and assembly, including generating additional genome sequence data and ancillary sequence data for annotation.
Collaborator Contribution The other partners in the SGSC have contributed in multiple roles, including genome sequencing and analysis. The roles of each partner are recorded in the pig genome sequence paper as published in Nature in 2012 (Groenen et al. 2012. Nature 491: 393-398)
Impact The primary output from this collaborative partnership was the publication of the draft reference genome sequence of the pig (Sus scrofa) in Nature in November 2012. Groenen et al. 2012. Nature 491: 393-398 and associated companion papers. The genome sequence data are accessible in the public DNA sequence repositories and the annotated sequence can be accessed in the three main genome browsers (Ensembl, NCBI, UCSC). The SGSC has a continuing interest in improving the reference genome sequence. However, this task is mainly being pursued by the founding core partners.