Implementing novel, cost effective alternatives to CIPC for sustainable potato storage

Lead Research Organisation: Cranfield University
Department Name: School of Water, Energy and Environment

Abstract

Potato is a major UK and worldwide crop required year-round by consumers and processors. Due to seasonal production,
long term storage is necessary, during which tubers must be maintained with good quality for fresh consumption and
processing. Potato tubers are natural over-wintering structures with a tendency to resume growth during storage, resulting
in sprouted produce that is unsuited to processing due to compositional changes such as increased sugar levels. Multiple
strategies are used to extend dormancy and minimise sprouting and waste, including the application of sprout
suppressants such as chlorpropham. Development of viable alternative strategies to maintain tubers and bulbs in a
dormant state and long-term suppression of sprouting are top industry priorities. Long-term storage of potato tubers is
essential for year round supply. Maintaining sprout suppression and low reducing sugars during storage is essential
paramount for supply quality and minimising the formation of acrylamide; key priorities for the processing industry. Potato
storage is still heavily reliant on the chemical chlorpropham (CIPC) to manage sprouting but further restrictions are coming
into force and its future registration is under scrutiny. Registered alternatives are becoming available, but there are
industry concerns over efficacy, cost and potential taint issues (a key issue problem for end product flavour and consumer
acceptability). The proposed work will build upon recent research into developing novel, cost effective, benign,
physiologically-targeted storage interventions which will suppress sprouting and maintain low sugar. This offers a route to
incremental reduction in and ultimately the elimination of CIPC within the UK and beyond.

Technical Summary

Long-term storage of potato tubers is essential for year round supply. Maintaining sprout suppression and low reducing sugars during storage of processing potatoes is paramount for supply quality and minimising the formation of acrylamide; key priorities for the processing industry. Potato storage is still heavily reliant on the chemical chlorpropham (CIPC) to manage sprouting but further restrictions are coming into force. The proposed work will build upon recent research and develop novel, cost effective, benign, physiologically-targeted storage interventions which will suppress sprouting and maintain low sugars. This offers a route to incremental reduction in and ultimately the removal of the use of CIPC within the UK and beyond.

Planned Impact

The UK processing potato industry is worth £3.9 billion at retail and supports more than 20,000 jobs in the industry directly,
on farms, transport and in manufacture. To achieve year round potato supply in the UK approximately 1.5 million tonnes of
potato tubers are typically stored for up to 8 months each season. Maintaining ecodormancy (sprout suppression)
combined with low reducing sugars is essential for end product quality and mitigating risk of formation of the process
contaminant acrylamide. Current storage practices for processing potatoes are reliant on CIPC to suppress sprouting in
combination with higher temperatures to avoid cold induced sweetening. The potato industry and especially the processing
sector is dependent on CIPC for storage quality; in 2012, a total of 31T of CIPC was applied across 89% of the stored crop (Defra).
The continued registration of CIPC remains very uncertain given UK regulatory concerns over the increasing
number of recent MRL exceedances, non-target binding, and potential cross contamination with other crops, and the
likelihood for the persistence of CIPC and its breakdown products in the environment. There has been increasing and
concerted pressure from the Chemical Residue Directorate for the processing industry to reduce its use. Alternative
chemical solutions are becoming available, but there are industry concerns over efficacy, increased cost and taint; the latter
being a key concern for end product flavour and consumer acceptance. Although the CIPC Stewardship Group has
improved CIPC compliance, it is no exaggeration that without CIPC the UK processing potato industry at present would not
be economically viable. Critically, without viable alternatives to CIPC, storage duration could be reduced from 8 months to 4
months or less. Consequently there would be a reduction in demand for UK grown potatoes equivalent to 4 months supply
(~ 750 kT) with a nominal farm gate value of >£150M @ £200/t; with commensurate reliance on imports and impacts of
self-sufficiency. This project addresses this challenge directly by developing benign, cost effective alternatives to CIPC
which are based on novel physiological insights and offers a route to incremental reduction in CIPC thereby ensuring
continued long-term storage capability and protecting domestic potato production and associated supply chains. Firstly, this
will counter the risk from future withdrawal of CIPC and the consequential contraction in the storage window from 8 to 4
months with associated reduction in demand for UK grown potatoes. Secondly it will address the limitations in existing and
emergent alternatives which either add cost, are less efficacious, risk elevated reducing sugar accumulation or leave a
taint. Adoption of these new technologies will not only secure UK potato production equivalent to 4 months supply but also
will safeguard associated UK jobs. It will mitigate against imports (to offset supply shortfall) plus the associated increased
transport costs and additional GHG emissions plus reduce the risk to quality from extended transport distances. The
adopted technologies will directly reduce and ultimately eliminate the use of CIPC, mitigating against MRL exceedances
and lowering residual CIPC in the environment. These technologies will require new approaches to potato
storage.Through its close supplier relationships PepsiCo is well positioned to drive adoption of the successful solution(s) in
a framework which allows the technologies to evolve alongside reduced CIPC use whilst mitigating risk and ultimately
building confidence and a commercial pull for the technologies.
 
Description The work is covered by a confidentiality agreement and thus results cannot be disclosed until the patent as been approved. However a viable alternative to CIPC has been discovered from this project. The research findings have become much more relevant [see below]

The potato industry is overly reliant on a longstanding synthetic sprout suppressant, chlorpropham (CIPC), with a total of 31T applied across 89% of the stored crop in the UK alone [1.8 million tonnes annually; Bryan et al., 2019]. Over the last 10 years, CIPC has been under regulatory scrutiny, and in June, 2019 the European Union approved the withdrawal of CIPC, such that the 2019-2020 season will be the last storage season where the application of CIPC will be permissible. The research has discovered and demonstrated that ethylene in combination with 1-MCP can be used as an effective alternative to CIPC. The patent was submitted in late 2018 and a further two patents
were submitted in 2020. The research was published in 2021 [Tosseti et al., 2021]
Exploitation Route The work is showed that 1) Continuous ethylene activates ACO transcription and respiration in potatoes; 2) 1-MCP completely inhibits the respiratory rise induced by continuous ethylene exposure; 3) Exogenous ethylene promptly activates parenchymatic ABA catabolism via CYP707A upregulation; 4) A Kunitz-type invertase inhibitor mediates ethylene-induced sweetening; 5) A physiologically targeted ethylene + 1-MCP treatment offers an alternative to CIPC [Tosetti et al., 2021]. All these ethylene-induced effects were negated by 1-MCP with one notable exception: 1-MCP enhanced the sprout suppressing effect of ethylene whilst preventing ethylene-induced sweetening.
Two further patents have been submitted in 2020 and we are awaiting confirmation.

For the BBSRC Seeding Catalyst - Three spectral wavelength areas of interest were identified. Potato tubers treated with a combination of sprout suppressants showed a different response pattern in those wavelengths compared to the control, especially towards the end of the storage period. These findings are currently being further investigated.
Sectors Agriculture, Food and Drink

URL https://www.sciencedirect.com/science/article/pii/S0925521420309923
 
Description PepsiCo have set up a new postharvest research team (with two ex Cranfield-educated [former PhD students of the PI] staff members) to support this research. The results have also been used to support three patent application and an accompanying publication [Tosetti et al., 2021] In summary a viable and unique alternative technology to CIPC has been discovered. The research findings have become much more relevant as CIPC has recently been banned by the EU [see below] The potato industry is overly reliant on a longstanding synthetic sprout suppressant, chlorpropham (CIPC), with a total of 31T applied across 89% of the stored crop in the UK alone [1.8 million tonnes annually; Bryan et al., 2019]. Over the last 10 years, CIPC has been under regulatory scrutiny, and in June, 2019 the European Union approved the withdrawal of CIPC, such that the 2019-2020 season will be the last storage season where the application of CIPC will be permissible.
First Year Of Impact 2021
Sector Agriculture, Food and Drink
Impact Types Economic

 
Description BBSRC Seeding Catalyst Award - Demonstrating the potential use of next generation phenotyping for potato storage management
Amount £23,937 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2018 
End 02/2019
 
Description Horticultural Crop Quality and Food Loss Prevention Network
Amount £375,715 (GBP)
Funding ID BB/T010819/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 01/2020 
End 01/2024
 
Description PepsiCo 
Organisation PepsiCo
Country United States 
Sector Private 
PI Contribution Master Service Agreement signed and renewed [confidential]
Collaborator Contribution Master Service Agreement signed and renewed [confidential]
Impact Master Service Agreement signed and renewed 2 patents Additional research commissioned [e.g. fully funded PhD and contract research] Members of Cranfield staff now working at PepsiCo [Dr Gemma Chope and Dr Kate Cools]
Start Year 2013
 
Title METHOD FOR THE STORAGE OF POTATO COMPRISING TREATMENT BY ETHYLENE AND 1-METHYLCYCLOPROPENE 
Description A method of storing potatoes includes providing a plurality of dormant potatoes, wherein the potatoes have been cured after harvesting; in a first treatment step, treating the potatoes with 1-methylcyclopropene by exposing the potatoes, which are at a first treatment temperature within the range of from 10 to 30° C., to 1-methylcyclopropene; storing the potatoes at a second storage temperature within the range of from 4 to 15° C.; and in a subsequent second treatment step during the storing step, treating the potatoes with ethylene by exposing the potatoes, which are at the second storage temperature, to ethylene. 
IP Reference US2021352924 
Protection Patent granted
Year Protection Granted 2021
Licensed Yes
Impact Linked Tosettii et al., 2021 - https://www.sciencedirect.com/science/article/pii/S0925521420309923
 
Title POTATO STORAGE 
Description A method of storing potatoes, the method comprising the steps of: iv. providing a plurality of dormant potatoes, wherein the potatoes have been cured after harvesting; v. treating the potatoes with 1-methylcyclopropene, the treatment comprising exposing the potatoes, which are at a first treatment temperature within the range of from 10 to 30°C, to 1-methylcyclopropene; storing the potatoes at a second storage temperature within the range of from greater than 6 to up to 15°C for a storage period within a potato store, wherein the storage period extends continuously until at least 1 week after initiation of eye movement in at least one of the potatoes, and wherein during the storage period the potatoes are stored in atmospheric air free of an external supply of ethylene sprout suppressant. 
IP Reference WO2021228421 
Protection Patent granted
Year Protection Granted 2021
Licensed Yes
Impact Linked to Tosetti et al., 2021
 
Title Potato Storage 
Description A method of storing potatoes comprises storing a plurality of endodormant or ecodormant potatoes in a first gaseous environment including carbon dioxide in an amount of from greater than the amount of carbon dioxide present in atmospheric air to up to 5 mol % based on the composition of the first gaseous environment; and in a subsequent storage step storing the potatoes in a second gaseous environment including carbon dioxide in an amount of from 0.03 to 2 mol % based on the composition of the second gaseous environment, the first and second gaseous environments having different carbon dioxide contents. The method may comprise: monitoring the dormancy of the potatoes; in response to eye movement of a potato, changing the first gaseous environment to a second gaseous environment; maintaining a level of carbon dioxide in the second gaseous environment below a selected threshold to control sugar content of the potatoes. 
IP Reference US2015079256 
Protection Patent application published
Year Protection Granted 2015
Licensed Commercial In Confidence
Impact This work formed some of the base technology for the UKRI/BBSRC Implementing novel, cost effective alternatives to CIPC for sustainable potato storage BB/M027295/1.
 
Description CAMBRIDGE UNIVERSITY POTATO GROWERS RESEARCH ASSOCIATION 30th ANNUAL CAMBRIDGE POTATO CONFERENCE 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact CAMBRIDGE UNIVERSITY POTATO GROWERS RESEARCH ASSOCIATION
30th ANNUAL CAMBRIDGE POTATO CONFERENCE 2019.
session 3 - 17:00-17:10 A novel alternative to CIPC for potato storage. Mac McWilliam, PepsiCo
Year(s) Of Engagement Activity 2019
URL https://www.niab.com/uploads/files/2019_CUPGRA_Conference_Programme.pdf
 
Description HAPi event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact HAPI dissemination event will take place on 10-11 December 2019 at the Park Plaza Hotel in Leeds. Mechanistic commonalities in potato, and onion storage
Leon Terry, Cranfield University
Year(s) Of Engagement Activity 2019
 
Description Interview for BBC radio 4, Farming today 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The purpose of the interview was to talk about how we can reduce food waste during postharvest, with a focus on the potato sector. We discussed about the research work carried out at the Plant Science Laboratory, Cranfield University, where ethylene supplementation has been used for sprout control. This research will have a direct impact for the processing potato industry since the most utilised commercial sprout suppressant has now been banned for its use.
Year(s) Of Engagement Activity 2020
URL https://www.bbc.co.uk/programmes/m000f5j3
 
Description Oral presentation of results to date at the AgriEPI BBSRC Seeding Catalyst Award event on 28th February 2019 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Agri-EPI Centre in conjunction with CHaP and Cranfield University organised an event to showcase results of the BBSRC Seeding Catalyst Awards focusing on the technology and applications of the Agri-EPI Centre / CHaP / Cranfield University Plant Phenotyping and Soil Health Facility. Relevant AgriEPI members were invited to attend.
Some of the results of the Seeding Catalyst project were presented and discussed. There was an interest on the potential application of the technology to reduce waste during potato storage.
Year(s) Of Engagement Activity 2019
URL https://www.agri-epicentre.com/event/bbsrc-seeding-catalyst-award-event-on-28th-february-2019/