An Anglo-French-German consortium to understand cerebellar contributions to emotional behaviour.
Lead Research Organisation:
University of Bristol
Department Name: Physiology and Pharmacology
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
Lawrenson C
(2021)
Cerebellar modulation of fear behaviour and memory encoding in the PAG
Paci E
(2022)
Cerebellar modulation of memory encoding in the periaqueductal grey and fear behaviour
in eLife
Iosif CI
(2023)
Cerebellar Prediction and Feeding Behaviour.
in Cerebellum (London, England)
| Description | This seed corn funding has led to the creation of a Virtual institute of 7 European universities and 9 non academic partners to study the cerebellum and emotional networks (CEN). CEN is a Marie Sklodowska-Curie Innovative Training Network funded by the European Research Council to explore the brain circuits that underlie emotional behaviour. The award for over 4.5 million euros creates a Virtual Institute of 7 European universities and 9 industry/charity partners. The funds will support 15 Early Stage Researchers (PhD students) working across the consortium over the next 4 years. Two or three PhD students will work on specific aspects of the scientific question at each University in the consortium. Every ESR will be co-supervised by a PI in another university in the network, including work placements. About half of the projects deal with fundamental studies in rodent models, which will enable a detailed description of the brain network processes at the level of individual and selected groups of nerve cells. The other half of the projects will look at cerebellar functions in humans, in healthy volunteers and in patients with diseases of the cerebellum and those with emotional problems such as anxiety disorders. |
| Exploitation Route | Potential for patients , clinicians and biotech companies to get involved in training network |
| Sectors | Healthcare,Pharmaceuticals and Medical Biotechnology |
| Description | This seed corn award led to a successful application for a Horizon2020 Marie Curie ITN which involves 8 European Universities and 9 non academic partners, led by Bristol |
| Sector | Education,Healthcare,Pharmaceuticals and Medical Biotechnology |
| Impact Types | Cultural,Societal,Economic |
| Description | CEN Innovative Training Network |
| Organisation | University Duisburg-Essen |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | I am the lead on a Marie Sklodowska-Curie Innovative Training Network funded by the European Research Council to explore the brain circuits that underlie emotional behaviour |
| Collaborator Contribution | Virtual Institute of 7 European universities and 9 industry/charity partners. |
| Impact | 15 ESRs funded across network |
| Start Year | 2021 |
| Description | Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Bennett, Apps, Cerminara, Whone, Goodfellow. (2018). Examining cerebellar-thalamo-cortical network dynamics in the harmaline rodent model of Essential Tremor. 1st International Tremor Congress. |
| Year(s) Of Engagement Activity | 2018 |
| Description | EU Consortium meeting Edinburgh |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Second meeting of the EU consortium to discuss plans for an ITN bid |
| Year(s) Of Engagement Activity | 2019 |
| Description | EU consortium meeing |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Study participants or study members |
| Results and Impact | EU consortium meeting in Brussel led to Marie Curie ITN application |
| Year(s) Of Engagement Activity | 2018 |
| Description | Role of the cerebellar-periaqueductal grey projection in auditory cued fear conditioning |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Poster presentation |
| Year(s) Of Engagement Activity | 2020 |