A simple, genome-editable technology for inducing steeper, deeper root growth in crops

Lead Research Organisation: University of Leeds
Department Name: Ctr for Plant Sciences

Abstract

This project builds directly on a BBSRC grant and PhD project that resulted in the discovery of a single, dominant point mutation in a gene regulating root growth angle causing more vertical lateral roots in the model plant Arabidopsis. This mutation is in a region of the gene that is conserved across many plant species and has the potential to be used to alter root architectures of many important crops. Root traits have a direct bearing on crop productivity via water and nutrient uptake making them an ideal high-value target for breeding/ biotechnological approaches to crop improvement. It is known that steeper roots improve water and nitrogen uptake in crop species, potentially increasing yields from lower input farming and under sub-optimal climate and soil conditions. This project will translate our findings into wheat as a proof of concept study in crops. Obtaining this proof of concept will provide vital data for patent filing and subsequent commercial exploitation.

Publications

10 25 50

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Roychoudhry S (2022) Auxin in Root Development. in Cold Spring Harbor perspectives in biology

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Roychoudhry S (2022) The Analysis of Gravitropic Setpoint Angle Control in Plants. in Methods in molecular biology (Clifton, N.J.)

 
Description This award supported the commercialisation of technology to manipulate root growth angle. Licensing options have been taken up by multinational biotech companies.
Exploitation Route Patent licensing
Sectors Agriculture, Food and Drink

 
Description The technology developed in this award is being evaluated under licence by a multi-national ag-biotech company.
First Year Of Impact 2001
Sector Agriculture, Food and Drink
Impact Types Economic

 
Title PLANTS HAVING A MODIFIED LAZY PROTEIN 
Description The invention relates to genetically altered plants with improved traits, in particular steeper root growth. The invention also relates to methods for making such plants and methods for modulating root growth, in particular methods that employ gene editing techniques. 
IP Reference WO2021064402 
Protection Patent granted
Year Protection Granted 2021
Licensed Commercial In Confidence
Impact Commercial, in confidence at present