UK-China partnership: Chromosomal Instability aiding Genetic Variants (CIVa) linked to human ageing
Lead Research Organisation:
Queen Mary University of London
Department Name: Sch of Biological & Behavioural Sciences
Abstract
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Publications
Dang D
(2023)
Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamics.
in The Journal of cell biology
Efstathiou C
(2021)
Electrically tunable lenses - eliminating mechanical axial movements during high-speed 3D live imaging.
in Journal of cell science
Song X
(2021)
Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation.
in Nature communications
| Description | How are mono-oriented chromosome-microtubule attachments protected to prevent errors in mitosis and associated cellular ageing? |
| Amount | £403,927 (GBP) |
| Funding ID | BB/W002698/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2021 |
| End | 09/2024 |
| Description | How are mono-oriented chromosome-microtubule attachments protected to prevent errors in mitosis and associated cellular ageing? |
| Organisation | Queen Mary University of London |
| Department | School of Biological and Chemical Science QMUL |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Conducted Super-resolution imaging; trained personnel on timelapse recording; and secured funding to expand the work. |
| Collaborator Contribution | Comparison across model systems; modelling of structures |
| Impact | Funding: https://gtr.ukri.org/projects?ref=BB%2FW002698%2F1 |
| Start Year | 2022 |
| Description | Online seminars with Beijing Agricultural university |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | 30 researchers attended an online meeting to discuss human variants. |
| Year(s) Of Engagement Activity | 2009,2021 |