Cellular Genomics (CELLGEN): Data Science for Cellular Genomics
Lead Research Organisation:
Earlham Institute
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
As a work package of the grant Cellular Genomics (CELLGEN) we will develop a data science ecosystem to enable us and the wider scientific community to interpret share and integrate cellular genomics datasets
Planned Impact
unavailable
Organisations
- Earlham Institute (Lead Research Organisation)
- AstraZeneca (Collaboration)
- Google (Collaboration)
- Quadram Institute Bioscience (Collaboration)
- WorldFish (Collaboration)
- Tropic Biosciences Ltd (Collaboration)
- Oxford Nanopore Technologies (Collaboration)
- The Wellcome Trust Sanger Institute (Collaboration)
- UNIVERSITY OF EAST ANGLIA (Collaboration)
- KING'S COLLEGE LONDON (Collaboration)
Publications
Cai Y
(2023)
Tuning Plant Promoters Using a Simple Split Luciferase Method to Assess Transcription Factor-DNA Interactions
in ACS Synthetic Biology
Chau C
(2024)
Automated Purification of DNA Origami with SPRI Beads.
in Small (Weinheim an der Bergstrasse, Germany)
Etherington G
(2023)
Schizosaccharomyces versatilis represents a distinct evolutionary lineage
Etherington GJ
(2024)
Schizosaccharomyces versatilis represents a distinct evolutionary lineage of fission yeast.
in Yeast (Chichester, England)
Felix Shaw
EI Single Cell Schemas
Hellmich C
(2023)
p16INK4A-dependent senescence in the bone marrow niche drives age-related metabolic changes of hematopoietic progenitors.
in Blood advances
Jibril A
(2023)
Plasma cell-derived mtDAMPs activate the macrophage STING pathway, promoting myeloma progression.
in Blood
Marcuccio F
(2024)
Single-cell nanobiopsy enables multigenerational longitudinal transcriptomics of cancer cells
in Science Advances
| Description | Engineering gene regulatory networks to design disease-resistant crops |
| Amount | £1,409,847 (GBP) |
| Funding ID | BB/Y007786/1 |
| Organisation | United Kingdom Research and Innovation |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2024 |
| End | 02/2026 |
| Description | LongTREC: The Long-Reads Transcriptomics European Consortium. The next generation transcriptome biology revealed by single molecule seq. technologies |
| Amount | £265,251 (GBP) |
| Funding ID | EP/X035913/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2022 |
| End | 09/2026 |
| Description | Astrazeneca |
| Organisation | AstraZeneca |
| Department | Research and Development AstraZeneca |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Analysis of long read bulk RNA-Seq for the detection of splicing variation in human cell lines upon chemical compounds exposure |
| Collaborator Contribution | Experimental data (cell exposed to different compounds), sequencing data |
| Impact | Multidisciplinary collaboration combining molecular biologists and computational biologists |
| Start Year | 2023 |
| Description | Collaboration - WorldFish |
| Organisation | Worldfish |
| Country | Malaysia |
| Sector | Charity/Non Profit |
| PI Contribution | As part of this collaboration we have been generating genomic resources and identifying the genetic bases of traits of interest |
| Collaborator Contribution | WorldFish has been providing samples for sequencing, genetic data |
| Impact | 10.1186/s12864-022-09065-8 |
| Start Year | 2020 |
| Description | Collaboration King College London |
| Organisation | King's College London |
| Department | Maurice Wohl Clinical Neuroscience Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Computational analyses of long read bulk and single cell data from human IPSCs with engineered mutation for Amyotrophic lateral sclerosis and derived neurons, bulk long reads RNA-Seq from mouse brains with human mutations for Amyotrophic lateral sclerosis |
| Collaborator Contribution | Generation of IPSC lines with causative mutations, generation of the mice lines with human mutation |
| Impact | The work is highly collaborative including clinicians, clinical geneticists, molecular biologists, cellular biologists, computational biologists |
| Start Year | 2023 |
| Description | Collaboration UEA Medical School |
| Organisation | University of East Anglia |
| Department | School of Medicine UEA |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Computational analyses of long read data to assess polyAdenylation sites usage during cardiomyocytes maturation, both in wild type background and in cell lines with mutations for cardiac disorders |
| Collaborator Contribution | IPSC generation, cardiomyocytes maturation |
| Impact | Computational analyses of differential polyadenylation usage during cardiomyocytes maturation |
| Start Year | 2024 |
| Description | Collaboration with Oxford Nanopore Technologies |
| Organisation | Oxford Nanopore Technologies |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | As part of the upcoming EI strategic programme we will be producing novel protocols for single cell long read RNA and DNA sequencing as well as novel approaches to detect DNA replication through base modification |
| Collaborator Contribution | ONT will contribute through providing expertise in machine learning models applications (base modification), technology solutions and protocols developments for single cell RNA / DNA seq |
| Impact | Engagement with ONT on March 7th to develop the collaboration as part of the upcoming ISPs |
| Start Year | 2022 |
| Description | Google Cloud |
| Organisation | |
| Department | Google UK |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | As part of this collaboration we will make available high dimension data sets and pipelines for analyses |
| Collaborator Contribution | As part of the collaboration Google Cloud will facilitate access to data sets and online analyses |
| Impact | This collaboration contributed to the submission of the CELLGEN ISP |
| Start Year | 2022 |
| Description | Impact of low protein diet on liver function upon Salmonella infection |
| Organisation | Quadram Institute Bioscience |
| Department | Gut Health and Food Safety |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | My team has performed FACS cell sorting and 10X analysis of immune cells in the liver. |
| Collaborator Contribution | Dr Beraza holds the project license enabling studies of the Salmonella infection and impact on liver function in M. musculus. Her team provided the expertise in immune cell isolation from the liver. |
| Impact | We are writing the manuscript, running title: Low protein diet exerts protective effect on liver function upon Salmonella infection. |
| Start Year | 2021 |
| Description | Panhematopoietic clonal and molecular analysis using RNA-barcoding approach |
| Organisation | University of East Anglia |
| Department | School of Medicine UEA |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I was performing FACS sorting of cells, isolated samples were included in published papers. |
| Collaborator Contribution | Dr Rushworth and his team provided wild type (C57Bl6, n=25) and PEPC Boy (n=20) mice and skills (intravenous injections). |
| Impact | Publications: 10.1172/JCI153157 10.1101/2022.05.16.491933 10.3389/fimmu.2022.1003006 10.1073/pnas.1913278116 10.1182/bloodadvances.2022007033 |
| Start Year | 2019 |
| Description | Tropic Biosciences |
| Organisation | Tropic Biosciences Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | As part of this collaboration we will be sequencing materials from Tropic Bioscience to identify variants segregating in their stocks, we will develop novel protocols for early assessment of plant embryos |
| Collaborator Contribution | As part of the collaboration Tropic Bioscience is providing material (tissues, DNA) and expertise |
| Impact | The collaboration contributed to the submission of the CELLGEN ISP |
| Start Year | 2022 |
| Description | Wellcome Trust Sanger Institute |
| Organisation | The Wellcome Trust Sanger Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Computational analyses of single cell long read data (PacBio, ONT) for human IPSC and differentiated neuronal lineages (astrocytes, motor neurons) |
| Collaborator Contribution | Cells (IPSCs, derived neuronal lineages), sequencing data |
| Impact | The work is multidisciplinary bringing together cellular biologists, molecular biologists, and computational biologists |
| Start Year | 2023 |
| Title | (Software) Bug Fixes | COPO Project |
| Description | In the Collaborative OPen Omics (COPO) website application, software bugs usually emerge upon observations from end-users or from a project team member's maintenance checks. A software bug is an error, flaw or fault in the design, development, or operation of COPO that causes it to produce an incorrect or unexpected result, or to behave in unintended ways. Debugging is the process used to try find, correct and reproduce or pinpoint the cause of the bug. Bug fixes are crucial interventions to safeguard against software failures, inaccuracies, economic losses and avoid repercussions from poor software quality. The bug fixes and a brief description of it are recorded in COPO GitHub repository. Some examples of bug fixes in COPO are: - Enable the COPO Accessions Dashboard web page which can be accessed at https://copo-project.org/copo/copo_accessions/dashboard, to be viewed by end-users who are not logged into COPO - Corrected the data structure and results displayed when the audit Application Programming Interface (API) methods are queried - Grammatical, typographical and syntax error fixes - Ensuring that a default value is set or an appropriate error message is displayed when a code exception occurs The COPO project team aims to focus on precision and endeavours to perform bug fixes in a timely manner in order to deliver a metadata broker website platform that is robust, reliable and economically viable. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Open Source License? | Yes |
| Impact | Notable impacts of bug fixes include: - Bugs fixes reflect the Collaborative OPen Omics (COPO) project team's commitment to support the research community by providing a portal for scientists to describe, store and retrieve data more easily, using community standards and public repositories that enable the open sharing of results - Bug fixes are a catalyst for operational efficiency, enhances end-users' experience and navigation of the COPO web application and prevents bugs to be raised by end-users (once they are discovered by the project team before the end-users) - Future COPO project team developers and members of the research community having the GitHub open-source/commit history can use it to relate to individual lines of code in the COPO project back to the original thought processes and reasoning behind why that code had been changed - Bug fixes prevent the inaccurate display of information on the COPO web application and improves the quality of the metadata broker service that COPO provides to the research community since the more bugs that are fixed, the more reliable the COPO project becomes - The quality and reliability of COPO are upheld once bugs are resolved and this results in COPO being a more robust and trustworthy metadata broker service to the research community - Fixing bugs in a timely manner can lead to the discovery of another bug which may not be apparent until the initial bug(s) have been fixed or the new discovered bug can be more severe than the initial bug(s) - Prevent end-users from incidentally creating duplicated samples when the 'Submit' button or 'Confirm' button is clicked by disabling the button which is still displayed during the processing period after the end-users have made metadata submissions/updates in COPO |
| URL | https://github.com/collaborative-open-plant-omics/COPO-production |
| Title | Applicaiton support |
| Description | Provide application support to user and also do performance tunning to COPO |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Impact | Help user to use COPO, solve COPO bug and do enhenancement based on user's requirement |
| URL | https://copo-project.org |
| Title | Audit Log | COPO Project New Feature |
| Description | In the Collaborative OPen Omics (COPO), the audit log provides a record of all update actions that have been performed on samples by sample providers, system (members of the COPO development team) and sample managers. Actions that trigger an update of samples are but not limited to: - When a sample manager accepts or rejects samples - When a sample provider reuploads/resubmits an amended manifest in COPO - When a sample request is made to the COPO project team to update samples (in accordance with the sample project guidelines and the sample manger's affirmation) |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2023 |
| Impact | Notable impacts include: - The audit Application Programming Interface (API) methods on the COPO API web page and audit records provide a tracking of the history of changes made to samples. The audit log increases stakeholders' awareness of sample changes, makes sample data more reliable and improves data quality. - The API methods are useful for querying as well as verifying sample updates and their integrity. Each audit log can be downloaded in a Comma-separated values (CSV) format or viewed in a json format via the API methods. - The audit API methods allows the scientific community to easily reference, access and fetch the open-source data from COPO without developing their own specialised methods. The results can reduce metadata duplication, avoid inconsistency between data held amongst various metadata brokers and can be used in analysis as well as publications. - The sample update log and Audit API methods include but are not limited to the following. Sample updates can be queried by the following using the Audit API methods: - The date and time of the update action - The user who performed the update - The update type of the action (e.g. user or system) - The field on which the value was changed - The outdated and new values of the sample fields that were updated - The identification (ID) and type of the sample that was updated |
| URL | https://copo-project.org/static/swagger/apidocs_index.html#/Audit |
| Title | Creation of API Method to Retrieve Sample Records by Sequencing Centre | COPO Project New Feature |
| Description | An Application Programming Interface (API) method was created to retrieve sample records in the Collaborative OPen Omics (COPO) project by sequencing centre. A dropdown list of available sequencing centres are provided to choose from in the API method. API methods were created to query COPO records by sample and manifest |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2024 |
| Impact | Sample managers, sample providers and any individual in the scientific community can analyse and be informed of the number sample records based on the centre where the samples have been sequenced. The results, which are produced in both csv format and json format, can be shared and incorporated in various publications, third parties and API methods for further analyses etc.. |
| URL | https://copo-project.org/static/swagger/apidocs_index.html#/Sample/get_sample_sequencing_centre |
| Title | ERGA Permits Deposition to B2DROP | COPO Project New Feature |
| Description | In the Collaborative OPen Omics (COPO) project, code was integrated to allow permits related to the European Reference Genome Atlas (ERGA) Tree of Life (ToL) project be deposited to a third party storage known as B2DROP. The permits are deposited to B2DROP after the samples that the permits are associated to have been accepted by sample manager. Each permit is deposited in a correlated taxonomy identification directory. B2DROP is a secure and trusted data exchange service for researchers and scientists to keep their research data synchronised and up-to-date and to exchange with other researchers. Permits pdf files provided by sample or manifest providers in COPO alongside a sample manifest to guarantee that the sample(s) in question can be legally transferred to the sequencing centre indicated, can be vouched at the indicated collection(s) and has been sampled in compliance with all applicable rules. The types of permits that can be submitted in COPO available are Ethics, Sampling and Nagoya. |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2023 |
| Impact | The integration of depositing European Reference Genome Atlas (ERGA) permits in COPO on B2DROP faciliates the following: - Submitted permits can be viewed after they have been submitted - Storage and sharing of permits submitted by sample submitters with members of the the ERGA Tree of Life (ToL) project group - A centralised location for permits according to their taxonomy identification since each permit is stored in a correlated taxonomy identification (taxon ID) directory |
| Title | Perform automatic test when user submit push the code changes for COPO to GITHUB |
| Description | We use CIRCLECI to activate the pipeline of automatic test when user push the codes changes to GITHUB. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Open Source License? | Yes |
| Impact | it is to ensure the code are tested before it it is released to production. |
| URL | https://copo-project.org |
| Title | Population Genomics Associated Project/Subproject Integration | COPO Project New Feature |
| Description | The Population Genomics (POP_GENOMICS) sample manifest adapts the European Reference Genome Atlas (ERGA) project sample manifest. Its data should be brokered and validated in COPO then, deposited to European Nucleotide Archive (ENA) via COPO. In COPO, a POP_GENOMICS samples are realised when: - "RESEQUENCING" is set as the value for the "PURPOSE_OF_SPECIMEN" field for all samples within a manifest and POP_GENOMICS - POP_GENOMICS and Biodiversity Genomics Europe (BGE) are set as associated project types for a work profile that is created in COPO. This profile is created by sample providers and it is the same profile that the samples/ manifest will be submitted under. |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2023 |
| Impact | Notable impacts include: - Enabling COPO to: - Support the submission and validation of ERGA manifests that relate to the Population Genomics (POP_GENOMICS) subproject - Accept manifests that have empty values for certain columns. COPO will then set a default value to the empty values according to the POP_GENOMICS Standard Operating Procedure (SOP) guidelines |
| Title | Project Development Team Documentation | COPO Project New Feature |
| Description | The Collaborative OPen Omics (COPO) project team documentation is hosted on the Earlham Institute's Confluence website and is accessible to only members of the COPO project team. It is a living document that will be updated as the COPO web application evolves. It is a guide to help new and existing members of the COPO project team understand the COPO system and understand how to use it so that they can continue the development of the COPO web application and provide a metadata broker service to the research community. |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2023 |
| Impact | Notable impacts of the COPO project team documentation include: - Limiting the need for extensive training and allows new project team members to get up to speed quickly and efficiently with the Collaborative OPen Omics (COPO) web application - Provides a consistent reference guide for all project team members - Allows for quick look up of information - Provides a guide on how to use the COPO system, solve notable bugs/user requests and how to navigate the system for the COPO users - The documentation reflects up-to-date procedures, methods and guidelines to navigate the COPO system from a project developer's perspective |
| Title | Provide Read submission / Assembly Submission / Seq Annotation Submission / Barcoding Submission in COPO |
| Description | Allow user to upload Files to ECS server and then use the files for different kind of submission to ENA. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Open Source License? | Yes |
| Impact | COPO user are able to submit Read / Assembly / Seq Annotation / Barcoding manifest to ENA |
| URL | https://copo-project.org |
| Title | Refactoring COPO backend system |
| Description | It is to refactor the existing COPO project which is a big python django application. Python libraries updated, obsolete code removed and cleaned and the whole django application was separated into various modulized django applications for easy maintenance. We also upgraded the VM to ubuntu 20.04 from 16.04 and upgraded the mongodb, postgress db, nginx to the latest version. Use cluster version of mongodb such that we can do the audit trail of collection update. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Open Source License? | Yes |
| Impact | It is easy to maintain and less security issue due to the upgrade on OS, python lib, DB and proxy server. |
| URL | https://copo-project.org |
| Title | Refactoring the deployment procedure for COPO |
| Description | We use docker container to run COPO. Previously there was no script to do the deployment and the containers were run by executing docker command one by one. We need to remember the commands and the environment variables for the container. Now we use docker stack to the deployment. All the configuration including the environment variables, volumn mapping, secrets, cpu/memory resources etc for the containers are written to a docker compose file. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Open Source License? | Yes |
| Impact | It is easy to maintain and easy to do deployment. From the compose file, we can always know the container configuration |
| Title | Sequencing Centres' & BGE Automatic Email Notification When ERGA Samples Are Accepted | COPO Project New Feature |
| Description | After European Reference Genome Atlas (ERGA) manifests have been submitted by end-users in the Collaborative OPen Omics (COPO) web application, they are accepted by sample managers and/ Biodiversity Genomics Europe (BGE) checkers once the samples are compliant to the guidelines outlined in the project's Standard Operating Procedure (SOP). My task was to integrate/trigger an automatic email notification in COPO to the Biodiversity Genomics Europe (BGE) partners, sequencing centre personnel, ERGA group personnel as well as to the manifest submitter when samples have been accepted by sample managers. |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2023 |
| Impact | Notable impacts include: - Increasing awareness and confirmation to the ERGA group personnel, sequencing centre contact points and sample providers that submitted ERGA samples have been accepted - Affirmation to the sample submitters that the submitted samples can be shipped now that they have been accepted - Affirmation to the sample submitters that the Material Transfer Agreement (MTAs) documents should be signed and sent to the ERGA point of contacts |
| Title | Software Architectural Design of COPO |
| Description | I have been responsible for the overall design and delivery of many new features in COPO over the past 12 months. Please see recent software output entries for further details. |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2023 |
| Open Source License? | Yes |
| Impact | The overall growth of COPO as a service |
| Title | Upgraded ToL Projects to Higher Versions | COPO Major Feature |
| Description | Upgraded the Collaborative OPen Omics (COPO) website application code, metadata validation rules and manifest metadata json schemas to manifest versions - 2.4.2, 2.4.3 and ultimately, manifest version 2.5 (which is the current manifest version to date). The upgrade was done to be compliant with the latest changes and requirements by the main Tree of Life (ToL) projects that are brokered through COPO. These projects are Aquatic Symbiosis Genomics (ASG), Darwin Tree of Life (DTOL) and European Reference Genome Atlas (ERGA). |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2023 |
| Impact | Notable impacts include: - Withdrawl of the 'SHORT_READ_SEQUENCING' term from manifests in manifest version 2.5 upgrade - NOT_COLLECTED being an option for the 'DECIMAL_LATITUTE' and 'DECIMAL_LONGITUDE' columns in manifests in manifest version 2.5 in upgrade - Addition of 'ETHICS_PERMITS_FILENAME' field, 'SAMPLING_PERMITS_FILENAME' field and 'NAGOYA_PERMITS_FILENAME' to columns to manifests in manifest version 2.3 upgrade - Addition of 'LATITUDE_START' field, 'LONGITUDE_START' field, 'LATITUDE_END' field, 'LONGITUDE_END' field in manifest version 2.4.2 in upgrade - Addition of 'PROXY_TISSUE_VOUCHER_ID_FOR_BIOBANKING' field in manifest version 2.4.2 in upgrade - Withdrawal of the field, 'GRID_REFERENCE', because its information is captured in the fields - 'DECIMAL_LATITUDE' and 'DECIMAL_LONGITUDE' in manifest version 2.4.2 in upgrade - Added 'DNA barcoding to be performed by GAL' as an option for the field, 'BARCODING_STATUS' in manifest version 2.4.2 in upgrade |
| URL | https://github.com/collaborative-open-plant-omics/COPO-production |
| Title | User Documentation | COPO Project |
| Description | The Collaborative OPen Omics (COPO) documentation was created using the Sphinx reStructuredText (reST) markup language and hosted on Read the Docs. Read the Docs is a popular platform for hosting documentation, and it is used by many open-source projects whereas Sphinx is a powerful tool that makes it easy to create professional documentation. This version of the COPO documentation replaces the previous version which was last updated in 2021. In addition, the Help section of the COPO web application was omitted and included in this version of the COPO documentation. The latest version of the COPO documentation comprises the following sections: - Getting Started This section provides an overview of the COPO web application. It includes information on how to create an account, log in, and navigate to the COPO web application. - COPO Profile This describes the types of work profiles that can be created in COPO as well as how to create and manage them. - COPO Data Submission This describes the various ways by which metadata can be uploaded and submitted to COPO. - COPO Data Updates This describes how submitted metadata can be updated in COPO and what metadata cannot be updated - COPO Data Discovery & Retrieval - This describes how to search for metadata in COPO and how to retrieve metadata from COPO - Advanced This describes how to set up the COPO project locally with Docker and with PyCharm or Visual Code Code (VSCode) - Polices This describes the policies that govern the use of COPO - Help This section describes the glossary of terms used in COPO web application, how to contact the COPO team regarding issues or enquiries and frequently asked questions (FAQs) |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Open Source License? | Yes |
| Impact | The new version of the COPO documentation provides users with a comprehensive and updated guide to using the COPO web application and the COPO API. It comprises the following sections: - Getting Started - COPO Profile - COPO Data Submission - COPO Data Updates - COPO Data Discovery & Retrieval - Advanced - Polices - Help |
| URL | http://copo-docs.readthedocs.io |
| Title | User Support | COPO Project |
| Description | As a User Support Specialist for the Collaborative OPen Omics (COPO) web application, my tasks involve but are not limited to the following: - Investigating, resolving and responding to enquiries and issues raised by end-users of the COPO web application and the Tree of Life (ToL) project group personnel in a timely manner - Granting sample metadata providers and sample metadata managers access to requested ToL project groups - Liaising with COPO's European Nucleotide Archive (ENA) point of contact to suppress duplicated and invalid samples - Recommending and/or performing minor actions (code-wise) to correct issues or bugs raised by COPO end-users - Adding child projects/subprojects to parent projects upon request in ENA - Updating Aquatic Symbiosis Genomics (ASG), Darwin Tree of Life (DTOL) and European Reference Genome Atlas (ERGA) sample records - Liasing with Wellcome Sanger Institute point of contacts to update DTOL records |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Impact | Notable impacts include: - Maintaining collaboration with the research community to utilise COPO to make metadata submissions - Enhancing sample providers' productivity and ability to proceed with manifest submissions when for example, samples are updated upon user request by COPO - Timely code bug fix, communication and response to COPO sample providers/submitters' enquiries enable the sample providers to meet their deadline in submitting sample metadata - Fixing issues and bugs in COPO increases user experience and productivity as well as the quality and reliability of the COPO web application - Updating sample metadata values upon request ensures that accurate metadata is provided and available in the wider research community - Granting users access to requested Tree of Life (ToL) project groups allows them to proceed with sample manifest submissions - Liaising with European Nucleotide Archive (ENA) point of contact to suppress samples that were redundant in COPO and should be permanently or temporarily removed - Provided a linkage to parent projects after having associated the subprojects to the parent/main projects in ENA |
| Title | ehancement to TOL project function on COPO |
| Description | 1. Allow user to submit images to Bioimage Archive 2. Upgrade the API version to connect to ENA. We use v2 ENA api which is asychnorous. 3. Send email to notify user and data manager when the sample is rejected by ENA 4. Allows sample user / manager to download the most update-to-date manifest from COPO. and then they can update the manifest and upload it again to COPO. In such a way, the samples are updated. Previously, we had to update the sample manually per user's request. 5. Identify and solve the duplicated submission to ENA 6. Capture the exception stack trace log to log file such that it is easy to trace the error 7. Add BGE-checker for ERGA BGE profile. If the sample is to Sanger Sequence Centre, once it is approved by BGE checker, it will be direct to Sanger user for approval before submitting to ENA. For other samples, once BGE checker approves, they will be submitted to ENA immediatedly. 8. Allow the sample managers to search the profile based on the keywords on samples. i.e. they can now search the profile by using sample's scientific name. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2023 |
| Open Source License? | Yes |
| Impact | make COPO more reliable and easy to use |
| URL | https://copo-project.org |
| Description | Attendance at Biocuration 2023 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attended conference to network and find out latest developments. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Attended Gordon Research Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lightning talk and poster presentation at this conference. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Big Data Workshop |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Gave talk on data management to PhD students. |
| Year(s) Of Engagement Activity | 2023 |
| Description | EI Innovate 2023 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | EI Innovate is an annual engagement event that provides insight into the Earlham Institute's research, exploring opportunities for innovation and collaboration, specialising in agri-food, biotech, med-tech and public health. It provided plenty of networking opportunities and allowed us to gain insight into our ongoing collaborations, explain how our expertise and facilities can be accessed and discuss potential ideas for new collaborations. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.earlham.ac.uk/events/ei-innovate-2023 |
| Description | EI Innovate annual stakeholder engagement event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | EI Innovate is an annual engagement event that provides insight into the Earlham Institute's research, exploring opportunities for innovation and collaboration. Specialising in agri-food, biotech, med-tech and public health, we have a wealth of experience collaborating with others to develop potential solutions to urgent industrial and societal challenges. EI Innovate events foster exciting and valuable conversations between academia and industry. An example of an exciting collaboration that resulted from a previous EI Innovate is the Hybrid Wheat Initiative, which connects 25 breeding companies and research institutes worldwide, to resolve the critical challenge of hybrid wheat. In 2023, we showcased our two new strategic programmes of research - Cellular Genomics and Decoding Biodiversity - and two National Bioscience Research Infrastructures (NBRIs) - Transformative Genomics and the Earlham Biofoundry. The programme included talks about Earlham expertise and capabilities, examples of collaborations, panel discussions, Innovation Showcase, exhibition, tours of the two National Bioscience Research Infrastructures (NBRIs) - Transformative Genomics and the Earlham Biofoundry, and networking. |
| Year(s) Of Engagement Activity | 2019,2020,2021,2022,2023 |
| URL | https://www.earlham.ac.uk/events/ei-innovate-2023 |
| Description | EI Seminar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave EI seminar |
| Year(s) Of Engagement Activity | 2024 |
| Description | Elixir UK all hands - Norwich |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Engaged in networking group discussions |
| Year(s) Of Engagement Activity | 2023 |
| Description | Elixir all-hands Dublin 2023 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a poster, and had discussion regarding development of ROCrate which led to several hackathons. |
| Year(s) Of Engagement Activity | 2023 |
| Description | FTMA4, visit at MRC Stem cell institute, Cambridge |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | PDRA< RA and a group leader visited the lab at MRC Stem Cell Institute to gain practical knowledge and experience in new cell assays. Possibility of joint funding application. The activities were supported by EI's FTMA4 award (BB/X017761/1) |
| Year(s) Of Engagement Activity | 2023 |
| Description | Find My Future STEMM 2023 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | FindMyFuture is an engagement event aimed at introducing Year 8 students to various STEMM careers. Members of EI chatted about their research and careers with the many students who visited our stand. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Gordon Research Conference in Single Cell Genomics |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented poster, lightning talk and networked. Discovered collaborators with whom I am currently preparing a grant. |
| Year(s) Of Engagement Activity | 2023 |
| Description | ISP all hands meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | ISP all hands meeting allow the interaction amongst all the work package members. In addition to project and impact progress updates, workshops are held to drive discussion in areas such as IDEA, policy impact, futher funding opportunities and more. |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | Image Processing Carpentries |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Devlivered Training |
| Year(s) Of Engagement Activity | 2023 |
| Description | Invited seminar - Stockholm - What Your Are Missing Matters - Characterisation of novel splicing events across brain tissues and during development |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited talk at a Oxford Nanopore Technology Event |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://nanoporetech.com/about/events/nanopore-days/nanopore-day-stockholm-2024#event-overview |
| Description | ON Helix New Horizons in Genetic Screening |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | 300 participants from private sector, NHS and academia attended ON Helix workshops over 4 days to discuss progress and challenges of personalised medicine, genetic screening to open up the discussion how to tackle new challenges the field encounters. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.onhelix.com/ |
| Description | PCA Core Network Participant Meeting (CPN) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Made connections and panned for future grant submission. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Poster Presentation - Muex: a method to identify novel microexons from long-read RNA sequence data - Kamil Hepak |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation at the ISMB/ECCB 2023 |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.iscb.org/ismbeccb2023 |
| Description | Presentation - Invited Seminar - University College Dublin - Characterization of novel splicing events across tissues and during cellular differentiation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited seminar at the School of Biology and Environmental Science University College Dublin |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presentation - Invited talk -BioIndustry Association - Genomics Advisory Committee - Characterisation of novel potential targets through the characterisation of novel splicing events |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Presentation as part of the Q1 genomics advisory committee meeting (BioIndusrty Association) |
| Year(s) Of Engagement Activity | 2024 |
| Description | Presentation - LongTrec meeting - Single cell sequencing with PACBIO |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Presentation of library preparation and data analysis of single cell long read sequencing to graduate students as part of the Maric Curie LongTrec network |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presentation - Oral Presentation - Activation Manifold of The Mouse Visual Cortex - Biological Complexity Group (University of Cambridge) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | A presentation on the application of manifold theory to representation learning in the mouse visual cortex at The University of Cambridge, Department of Chemical Engineering and Biotechnology. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presentation - Oral Presentation - Annotation and characterisation of functional noncoding RNA - DARPA meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation in Boston as part of a DARPA initiative |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presentation - Oral Presentation - Characterization of novel splicing events across tissues and during cellular differentiation - WCBR |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at the Winter Conference on Brain Research as part of the session Fostering Successful Partnerships Between Academia and Industry |
| Year(s) Of Engagement Activity | 2024 |
| Description | Presentation - Oral Presentation - Megakaryocyte Flow Cytometry Image Analysis - Image Analysis Across Domains Seminar (Alan Turing Institute) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A presentation to the Alan Turing Institute image analysis community showing early data from megakaryocyte flow cytometry experiments and requesting feedback and possible methodological approaches to determine how best to analyse the images produced by the project so far and in the future (e.g. from upcoming widefield spatial transcriptomics images). |
| Year(s) Of Engagement Activity | 2024 |
| Description | Presentation - Oral Presentation - Philosophical Implications of Physicalism for the Natural Sciences - Philosophy and History Seminar (Alan Turing Institute) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Start of a new seminar series on the interaction between the sciences, AI and humanities open to Alan Turing Institute employees and partner institutions (e.g. Roche pharmaceuticals and universities), aimed at fostering new understanding through interdisciplinary dialogue on foundational topics in these areas. The seminar was attended by a group of roughly 15 (including online and in person) with plans to deceminate to a wider group via a video recording (link not yet available). Talked fostered discussion and interest in the metaphysical and ethical consequences of philosophical naturalism. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Presentation - Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Presentation to the LongTrec Consortium |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presentation at Norwich Cancer research network |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | 20 scientists attended the presentation on new methods and their applications and how to implement them in their own research. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Presentation at the Festival of Genomics and Biodata 2024 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Presentation on RNA barcoding and its application to study the platelet biogenesis in different contexts. It sparked questions and the discussion on potential applications in other research groups and a potential interaction with the industrial partner. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://festivalofgenomics.com/london/en/page/home |
| Description | Presentation to John Innes Foundation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Presented 'Data driven plant science' to John Innes Foundation Science subcommittee. This has helped secure continued funding for PGRs. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Presentation to the Kick-off meeting of LongTrec - Single cell sequencing on PACBIO |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Attendance and presentation to the LongTrec kickoff meeting in Valencia |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presentation, Pint of Science, Norwich |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | I gave the presentation on the effect of diet on the immune system function. It sparked questions about the food choices impacting our immunity, health and longevity. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://pintofscience.co.uk/events/norwich |
| Description | Quarterly Institution Strategic Programme Work package meetings |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | ISP work package meetings are hybrid and open to and involve all participants in the ISPs, including partners. The meetings include 1-3 oral presentations showcasing ongoing work and roundtable discussions on successes, barriers, and opportunities. |
| Year(s) Of Engagement Activity | 2023,2024 |
| Description | Researcher visit from Rijksuniversiteit of Groningen, Groningen, Netherlands |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Seminar at EI on the history of clonal studies from bacteria to mammals, outlook into naturally occurring barcodes-possibilites and limitations. Discussion about new algorithms/pipelines to improve the analysis. Individual discussions on current practices and available pipelines. The activities were supported by EI's FTMA4 award (BB/X017761/1) |
| Year(s) Of Engagement Activity | 2023 |
| Description | Single-cell show and tell |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | We organized the single-cell show and tell to showcase our equipment in the single-cell laboratories, talk about our workflows and provide some hands on lab experience to our colleagues within EI. We had 38 participants with different scientific and non-scientific backgrounds. The feedback was very positive, and most people would like to see other groups organize similar events. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Single-cell show-and-tell: Activity based tours of the EI single-cell labs |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | 40 staff from EI were given an interactive tour of the single-cell labs. We introduced them to the different platforms and concepts behind single-cell analysis. We hosted staff from operations, communications, business development and faculty, all staff at EI were invited. The event stimulated questions and discussion about both the biology and technology associated with single cell work. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Software Carpentries |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Delivered training |
| Year(s) Of Engagement Activity | 2023 |
| Description | Sphere Fluidics -Cambridge |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | PDRA, RA and Group Leader engaged with the industry-Sphere Fluidics to optimise bespoke microfluidc assays using their equipment. Obtained preliminary data for a grant application. The activities were supported by EI's FTMA4 award (BB/X017761/1) |
| Year(s) Of Engagement Activity | 2023 |
| Description | Teaching Assistant for Data Carpentry Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Attendees required either set-up assistance or assistance when issues emerged for the Software Carpentry topics - Data Organisation in Spreadsheets and Data management with SQ. The topics taught the fundamental data skills needed for anyone that deals with data and datasets. Ultimately, the attendees should be able to more effectively manage and analyse data as well as apply the tools and approaches directly to their ongoing research. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.earlham.ac.uk/events/data-carpentry-workshop-2024 |
| Description | Teaching Assistant for Software Carpentry Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Periods of being a Software Carpentry teaching assistant: 12th December, 2023 - 14th December, 2023 (URL: https://www.earlham.ac.uk/events/software-carpentry-workshop-dec23) 7th February, 2023 - 10th February, 2023 (URL: https://www.earlham.ac.uk/events/software-carpentry-workshop-2023) Attendees required either set-up assistance or assistance when issues emerged for the Software Carpentry topics - The Unix Shell, Version Control with Git and Programming with Python. The topics enabled attendes to use the shell to do more in less time, write structured programs and use Git to manage and share information. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.earlham.ac.uk/events/software-carpentry-workshop-dec23 |
| Description | UEA Pharmacology Student Visit - 12 Feb 2024 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | 13 students, plus a staff member, from the University of East Anglia, attended Earlham Institute for an afternoon. They participated in lab tours of Genomics Pipelines, Single-cell Labs, and the Biofoundry. They then heard talks from researchers (talk titles below), and had an informal discussion with current PhD students at EI. Overview: What it means to do a PhD DNA replication singled out Characterisation of alternative splicing regulation in the brain Clonal and molecular studies of haematopoiesis Mining Meadows: Exploring the biosynthesis of bioactive compounds in medicinal plants |
| Year(s) Of Engagement Activity | 2024 |
| Description | Visit from NNUH clinicians to the Earlham Institute on 19 June 2023 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | BDI team and IM of the Earlham Institute organised the visit from NNUH clinicians to the Earlham Institute. We held a workshop for researchers and clinicians to discuss their interests in developing potential collaborative projects that would utilise earlham expertise and capabilities and NNUH access to patients and patient data, and to the Norwich Biorepository. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Workshop between Earlham and Eagle Genomics |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | A visit 7 Earlham colleagues to Eagle Genomics in London to build a collaborative framework between Eagle and Earlham, as part of collaborations with DECODE and CELLGEN ISPs. Key areas of the framework include IP management, software licensing; terms of access to EI tools and data; standardisation of tools and data to enable commercialisation; and areas of joint research interests resulting in publications (animal health and probiotics, soil health). This visit was funded through the BBSRC FTMA4. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Workshop for MRes students in Genomics and Evolution |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | WOrkshop on capabilities enabled by single cell genomics, discussion of a selected scientific article. Critical assessment of the strengths and weaknesses of performed experiments. |
| Year(s) Of Engagement Activity | 2023 |
| Description | https://www.earlham.ac.uk/news/earlham-institute-BBSRC-funding-award-2023 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | We issued a press release to mark the 5-year funding award from BBSRC, which supports the Earlham Institute, ISPs, and NBRIs. We secured widespread regional media coverage, including BBC Look East and online, ITV Anglia, and the EDP. The feedback from BBSRC on this coverage was very positive, particularly due to competing stories on life science funding. The launch campaign received around 28.5k impressions and 1,000 engagements across social media platforms, with the launch tweet achieving 330 engagements on its own. The majority of ISP partners engaged either by sharing ours posts or publishing their own messages, which included Kew Science, UK CEH, Eagle Genomics, and PacBio. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.earlham.ac.uk/news/earlham-institute-BBSRC-funding-award-2023 |