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Decoding Biodiversity (DECODE): Genome Enabled Analysis Of Diversity To Identify Gene Function Biosynthetic Pathways And Variation In Agri/Aquacultural Traits

Lead Research Organisation: Earlham Institute
Department Name: UNLISTED

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

A work package of the grant Decoding Biodiversity (DECODE) this project will use the tools we have developed to investigate biodiversity in publicly available genomes. We will use multiple analytical approaches to: assign function to genomic dark matter-genes of currently unknown function; investigate mechanisms underpinning chemical diversity in plants; and identify mechanisms driving genetic diversity in key agricultural crops and aquaculture species.

Planned Impact

unavailable
 
Description Advocacy to the House of Lords Science and Technology Select Committee
Geographic Reach National 
Policy Influence Type Contribution to a national consultation/review
Impact As a result of EI's evidence, the Committee's report included policy recommendations aligned to the Earlham Institute's advocacy especially on investment and skills. Since the enquiry, the Government has endorsed the role of the UK's life science sector as one of the most strategically important areas for development in the Modern Industrial Strategy. This policy will generate subsequent regulatory and investment decisions that will impact our work significantly.
URL https://publications.parliament.uk/pa/ld5901/ldselect/ldsctech/55/5502.htm
 
Description DEFRA's Expert Panel on Digital sequence information on genetic resources
Geographic Reach National 
Policy Influence Type Participation in a guidance/advisory committee
Impact Recommendation submitted to COP15
 
Description Biodiversity, wellbeing and colour: wildflower genomics to inform the creation of new habitat
Amount £20,000 (GBP)
Funding ID DEVEGA_E22DTP1A 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 09/2022 
End 09/2026
 
Description Boosting innovation in breeding for the next generation of legume crops for Europe
Amount £368,936 (GBP)
Funding ID 10077978 
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 08/2023 
End 02/2028
 
Description Characterising Rice Genetic Diversity of the Past to Safeguard the Future
Amount £100,000 (GBP)
Funding ID 2869278 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 09/2023 
End 09/2027
 
Description Connecting Research Culture Conference
Amount £59,558 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 06/2024 
End 05/2025
 
Description Data science to feed a changing world: superior drought tolerance in nutritious traditional beans
Amount £100,000 (GBP)
Funding ID 2578607 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 08/2021 
End 09/2025
 
Description EBioAct: Environmentally sustainable production of bioactive triterpenes
Amount £1,680,889 (GBP)
Funding ID BB/Y007751/1 
Organisation United Kingdom Research and Innovation 
Sector Public
Country United Kingdom
Start 02/2024 
End 02/2026
 
Description Earlham Institute and Tozer Seeds Limited KTP 23_24 R5
Amount £176,013 (GBP)
Funding ID 10102570 
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 07/2024 
End 02/2027
 
Description Engineering gene regulation in plants to yield predictable expression
Amount £772,877 (GBP)
Funding ID APP36048 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2025 
End 04/2028
 
Description Global Center: International Research Center for Enhancing Plant Resilience
Amount £2,124,544 (GBP)
Funding ID APP41752 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2025 
End 04/2030
 
Description John Innes Foundation internship in data-driven plant bioinformatics
Amount £38,000 (GBP)
Organisation John Innes Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2021 
End 08/2023
 
Description Leverage Yellow Common Bean Native Variety Liborino as a bioproduct for the sustainable and peaceful socioeconomic development of the rural communities in Colombia
Amount £49,852 (GBP)
Funding ID 527023146 
Organisation British Council 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2020 
End 10/2021
 
Description Lucky and resilient: Genomic improvement of cold tolerance in red and white clover
Amount £125,000 (GBP)
Funding ID 2929096 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 08/2024 
End 09/2028
 
Description Safeguarding UK's best-loved fruit: immunity diversity in banana cultivars
Amount £100,000 (GBP)
Funding ID 2586708 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 08/2021 
End 09/2025
 
Description Undergraduate (sandwich) Internship (12 months)
Amount £22,924 (GBP)
Organisation Royal Botanic Gardens, Kew 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2023 
End 09/2024
 
Title Adaptation of pruning pipeline 
Description We adapted the pruning algorithm designed by Zhang et al., 2018 in their software AllHiC to be used with OmniC data 
Type Of Material Computer model/algorithm 
Year Produced 2023 
Provided To Others? No  
Impact Enabled us to create our genome assembly and the method will be published 
 
Title Annotated Genome assembly 
Description The first haplotype aware assembly of the teatraploid Urochloa decumbens 
Type Of Material Data analysis technique 
Year Produced 2023 
Provided To Others? No  
Impact Collaborations with Embrapa and CIAT. Increase skills in institute. Knowledge about species. Development of pipelines. 
 
Title Functional annotation for the Abbassa genome assembly 
Description Functional annotation for the Abbassa genome assembly 
Type Of Material Database/Collection of data 
Year Produced 2025 
Provided To Others? Yes  
Impact na 
 
Title Fusarium Pan-Annotations: improved individual and collective genome annotations 
Description A 'pan-annotation' of genomes from 77 taxa (83 accessions) across the genus Fusarium, delivered as part of the Earlham Institute Strategic Programme Grant 'Decoding Biodiversity' (BBSRC). Manuscript and annotation workflow tutorial in prep. 
Type Of Material Database/Collection of data 
Year Produced 2024 
Provided To Others? Yes  
Impact -Establishment of effective 'pan-annotation' reannotation workflow -Improved annotation quality both individually and collectively for Fusarium genomes -Detection of different rates of alternative splicing across Fusarium species complexes 
URL https://zenodo.org/doi/10.5281/zenodo.13829922
 
Title Fusarium Pan-Annotations: improved individual and collective genome annotations 
Description A 'pan-annotation' of genomes from 77 taxa (83 accessions) across the genus Fusarium, delivered as part of the Earlham Institute Strategic Programme Grant 'Decoding Biodiversity' (BBSRC). Manuscript and annotation workflow tutorial in prep. 
Type Of Material Database/Collection of data 
Year Produced 2024 
Provided To Others? Yes  
URL https://zenodo.org/doi/10.5281/zenodo.13829921
 
Title MxG transcriptomic response to drought and flooding PRJEB86745 
Description 105 RNAseq libraries exploring the transcriptomic response of Miscanthus x giganteus to early or late drought and flooding stresses on controlled conditions. 
Type Of Material Database/Collection of data 
Year Produced 2025 
Provided To Others? Yes  
Impact Collaboration between IBERS and EI demonstrates the complementary skills of both institutes. This project fits into the interest on expression dynamics on hybrid allopolyploids. The results will help design biomarkers, better understand the biology of the commercial Mxg cultivar, and feed into future research on stress priming and epigenetics. 
URL https://www.ebi.ac.uk/ena/browser/view/PRJEB86745
 
Title Pipeline to phasing and scaffolding heterozygous outcrossed polyploid and diploid genomes based on pruning Hi-C data 
Description The major problem of scaffolding polyploid genome is that Hi-C signals are frequently detected between allelic haplotypes and any existing stat of art Hi-C scaffolding program links the allelic haplotypes together. To solve the problem, we developed a new Hi-C scaffolding pipeline tailored to the polyploid genomes and tested it to anchor the tetraploid genome of Brachiaria decumbens cv. Basilisks that we previously sequenced with HiFI. We also generated Hi-C reads for the red clover cultivar cv. Milvus that we sequenced using HiFi reads in a previous funding scheme. 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? No  
Impact The major problem of scaffolding polyploid genome is that Hi-C signals are frequently detected between allelic haplotypes and any existing stat of art Hi-C scaffolding program links the allelic haplotypes together. To solve the problem, we developed a new Hi-C scaffolding pipeline tailored to the polyploid genomes and tested it to anchor the tetraploid genome of Brachiaria decumbens cv. Basilisks that we previously sequenced with HiFI. We also generated Hi-C reads for the red clover cultivar cv. Milvus that we sequenced using HiFi reads in a previous funding scheme. 
 
Title Sequencing data for the genome assembly and annotation of the Nile tilapia Abbassa elite strain 
Description Sequencing data for the genome assembly and annotation of the Nile tilapia Abbassa elite strain 
Type Of Material Database/Collection of data 
Year Produced 2025 
Provided To Others? Yes  
Impact na 
URL https://www.ebi.ac.uk/ena/browser/view/PRJEB57170
 
Title Tilapia genetic diversity across the Lake Victoria Basin 
Description Genotypes for Oreochromis niloticus, O. leucosticus, O. variabilis, O. esculentus, Coptodon rendalli, C. zillii collected in water bodies in Kenya, Tanzania, and Uganda within the Lake Victoria Basin. 
Type Of Material Database/Collection of data 
Year Produced 2024 
Provided To Others? Yes  
Impact na 
URL https://zenodo.org/doi/10.5281/zenodo.11193181
 
Description Anti-inflammatory properties of plant natural products 
Organisation University of East Anglia
Department Schools of Pharmacy and Medicine UEA
Country United Kingdom 
Sector Academic/University 
PI Contribution Identification and production of plant extracts and natural products with proposed anti-inflammatory activity.
Collaborator Contribution Testing the anti-inflammatory activities of plant natural products in human cell lines
Impact Data on the anti-inflammatory activities of plant natural products.
Start Year 2021
 
Description CIAT and EMBRAPA: Understanding genomics of Urochloa 
Organisation Brazilian Agricultural Research Corporation
Department Embrapa Cerrados
Country Brazil 
Sector Public 
PI Contribution We assembled and annotated a high quality genome of the polyploid Urochloa decumbens which can be used to by our collaborators to identify genes and markers relevant for breeding.
Collaborator Contribution Provided us with data from another Urochloa species so we could explore and understand the ancestry of Urochloa decumbens
Impact Outcome is we have added to the knowledge of the community by understanding the ancestry of Urochloa decumbens and identifying structural rearrangements that will contribute to our understanding of this forage species and its traits.
Start Year 2023
 
Description CIAT and EMBRAPA: Understanding genomics of Urochloa 
Organisation Brazilian Agricultural Research Corporation
Department Embrapa Genetic Resources and Biotechnology
Country Brazil 
Sector Private 
PI Contribution We assembled and annotated a high quality genome of the polyploid Urochloa decumbens which can be used to by our collaborators to identify genes and markers relevant for breeding.
Collaborator Contribution Provided us with data from another Urochloa species so we could explore and understand the ancestry of Urochloa decumbens
Impact Outcome is we have added to the knowledge of the community by understanding the ancestry of Urochloa decumbens and identifying structural rearrangements that will contribute to our understanding of this forage species and its traits.
Start Year 2023
 
Description CIAT and EMBRAPA: Understanding genomics of Urochloa 
Organisation CGIAR
Department International Center for Tropical Agriculture
Country Colombia 
Sector Charity/Non Profit 
PI Contribution We assembled and annotated a high quality genome of the polyploid Urochloa decumbens which can be used to by our collaborators to identify genes and markers relevant for breeding.
Collaborator Contribution Provided us with data from another Urochloa species so we could explore and understand the ancestry of Urochloa decumbens
Impact Outcome is we have added to the knowledge of the community by understanding the ancestry of Urochloa decumbens and identifying structural rearrangements that will contribute to our understanding of this forage species and its traits.
Start Year 2023
 
Description Collaboration between ISPs: DECODE and Resilient Crops (monthly meeting) 
Organisation Aberystwyth University
Department Institute of Biological, Environmental and Rural Sciences (IBERS)
Country United Kingdom 
Sector Academic/University 
PI Contribution Monthly online meeting between staff and students between both institutes working in IBERS' WP4 or EI's WP2 ISP objectives. There were kick-off visits to both IBERS and EI from the respective ISP leads. EI hosted IBERS' ISP PI (KF) during a 3 day visit. We agreed shoared objectives on clovers, ryegrass, Miscanthus and oats pangenomics that reuse tools and knowhow generated in DECODE.
Collaborator Contribution Monthly online meeting between staff and students between both institutes working in IBERS' WP4 or EI's WP2 ISP. We hosted IBERS' ISP PI (KF) during a 3 days visit, and agreed a follow-up visit to identify further areas of coordination between both ISPs.
Impact TBD
Start Year 2023
 
Description Collaboration with Elsoms Group (CASE - CD) - Understanding variation in flowering-related traits among commercially important Apiaceae herb species. 
Organisation Elsoms Seeds
Country United Kingdom 
Sector Private 
PI Contribution Expertise and Know-How in marker discovery for plant breeding. Expertise and Know-How in identification of genetic diversity across large biological collections. Expertise and Know-How in sequencing and bioinformatics analysis of plant genomes. Knowledge and expertise in genebanks and genotyping orphan crops. Computational and bioinformatics expertise and best practice.
Collaborator Contribution Plant material and breeding knowhow for Apiaceae herb species
Impact CASE Studentship agreement.
Start Year 2022
 
Description Collaboration with IBM Research, STFC, and RAGT - HNCDI Excelerate 
Organisation IBM
Department IBM Research in the UK
Country United Kingdom 
Sector Private 
PI Contribution Earlham is contributing by genomic data for 27 UK wheat varieties and wheat pan-transcriptome data.
Collaborator Contribution IBM will design, develop, and test the bioinformatic workflow to enable processing of genomic and developing statistical and ML predictions of potential useful genetic variation and markers for valuable agricultural traits. RAGT brings expertise in plan breeding. STFC Hartree Centre brings expertise in supercomputing, data science and artificial intelligence (AI) technologies for enhanced productivity, smarter innovation and economic growth.
Impact No outputs or outcomes yet.
Start Year 2023
 
Description Collaboration with IBM Research, STFC, and RAGT - HNCDI Excelerate 
Organisation RAGT Seeds
Country United Kingdom 
Sector Private 
PI Contribution Earlham is contributing by genomic data for 27 UK wheat varieties and wheat pan-transcriptome data.
Collaborator Contribution IBM will design, develop, and test the bioinformatic workflow to enable processing of genomic and developing statistical and ML predictions of potential useful genetic variation and markers for valuable agricultural traits. RAGT brings expertise in plan breeding. STFC Hartree Centre brings expertise in supercomputing, data science and artificial intelligence (AI) technologies for enhanced productivity, smarter innovation and economic growth.
Impact No outputs or outcomes yet.
Start Year 2023
 
Description Collaboration with Syngenta Crop Protection R&D 
Organisation Syngenta International AG
Department Syngenta Crop Protection
Country United Kingdom 
Sector Private 
PI Contribution TBA
Collaborator Contribution TBA
Impact TBA
Start Year 2022
 
Description Collaboration with data management working group (Lars-Otto Gernot and Ivo Rieu) for Legume Generation 
Organisation IPK Gatersleben
Country Germany 
Sector Private 
PI Contribution We have worked together to establish best data management practices within the legume generation project, e.g. crop and gene ontologies, and to standardise procedures across multiple partners. WE are working with BELIS to maintain these standards between projects.
Collaborator Contribution They have assisted in maintaining standards at other partner institutes and providing input to us in ways to standardise procedures
Impact We have worked together to establish best data management practices within the legume generation project, e.g. crop and gene ontologies, and to standardise procedures across multiple partners. WE are working with BELIS to maintain these standards between projects.
Start Year 2024
 
Description Collaboration with data management working group (Lars-Otto Gernot and Ivo Rieu) for Legume Generation 
Organisation Radboud University Nijmegen
Country Netherlands 
Sector Academic/University 
PI Contribution We have worked together to establish best data management practices within the legume generation project, e.g. crop and gene ontologies, and to standardise procedures across multiple partners. WE are working with BELIS to maintain these standards between projects.
Collaborator Contribution They have assisted in maintaining standards at other partner institutes and providing input to us in ways to standardise procedures
Impact We have worked together to establish best data management practices within the legume generation project, e.g. crop and gene ontologies, and to standardise procedures across multiple partners. WE are working with BELIS to maintain these standards between projects.
Start Year 2024
 
Description Collaboration with wildflower seed companies 
Organisation Emorsgate Seeds
Country United Kingdom 
Sector Private 
PI Contribution Current work is being done under the Wildflower PhD to investigate the biological effects of the seed production process, this would potentially provide more seed samples to expand the work.
Collaborator Contribution Ongoing discussions about future access to seed samples.
Impact None yet
Start Year 2024
 
Description Collaboration with wildflower seed companies 
Organisation National Wildflower Centre
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Current work is being done under the Wildflower PhD to investigate the biological effects of the seed production process, this would potentially provide more seed samples to expand the work.
Collaborator Contribution Ongoing discussions about future access to seed samples.
Impact None yet
Start Year 2024
 
Description Emorsgate seed production life-cycle project 
Organisation Emorsgate Seeds
Country United Kingdom 
Sector Private 
PI Contribution We are sampling from multi-generation seed pedigrees to characterise the effect of their bulking process on genetic diversity.
Collaborator Contribution The partner are providing expertise in native seed production and access to their seed production database in addition to corresponding seed material from cold storage. We were invited for a tour of their facilities and have discussed the aims of the research project to identify pedigree lines of scientific interest.
Impact We are just at the stage of receiving seed lots that have been selected for analysis. No results to report currently.
Start Year 2024
 
Description Engineering triterpene production 
Organisation John Innes Centre
Country United Kingdom 
Sector Academic/University 
PI Contribution Expertise and methods in genome editing and pathway enginering.
Collaborator Contribution Expertise in the detection of triterpenoids.
Impact Collaborative grants funded: "21EBTA specialised metabolism and new cellular architectures in plants" + "EBioAct: Environmentally sustainable production of bioactive triterpenes"
Start Year 2020
 
Description FTMA GRIT team in Sanger Insitute 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution This was mainly a training residential stay to learn how to use their pipelines and benefit from their expertise so currently we have not made a contribution to them.
Collaborator Contribution Spent a week learning how to use their pipelines and benefiting from their expertise by being taught how to perform manual curation in order to produce high quality genome assemblies.
Impact High quality chromosome level haplotype aware genome assembly of Urochloa decumbens. Learning how to use GRIT curation teams pipeline and how to manually curate genomes using HiC data.
Start Year 2023
 
Description Improving breeding of Urochloa and understanding genus 
Organisation University of Leicester
Country United Kingdom 
Sector Academic/University 
PI Contribution Contributed expertise and will contribute data reads and assemby for Urochloa
Collaborator Contribution Expertise
Impact Currently exchange of expertise - collab very recent.
Start Year 2024
 
Description Miscanthus genome, pangenome 
Organisation Earlham Institute
Country United Kingdom 
Sector Academic/University 
PI Contribution Miscanthus sacchariflorus genome sequence, Miscanthus RNAseq data
Collaborator Contribution Miscanthus sinensis genome sequence (https://phytozome.jgi.doe.gov/pz/portal.html#!info?alias=Org_Msinensis_er), Miscanthus RNAseq data, Miscanthus molecular markers
Impact Mitros et al. Genome biology of the paleotetraploid perennial biomass crop Miscanthus. Nat Commun 11, 5442 (2020). https://doi.org/10.1038/s41467-020-18923-6 De Vega J, Donnison I, Dyer S, Farrar K. Draft genome assembly of the biofuel grass crop Miscanthus sacchariflorus. F1000Res. 2021 Jan 18;10:29. doi: 10.12688/f1000research.44714.1. PMID: 33732433; PMCID: PMC7921889.
Start Year 2014
 
Description Miscanthus genome, pangenome 
Organisation HudsonAlpha Institute for Biotechnology
Country United States 
Sector Charity/Non Profit 
PI Contribution Miscanthus sacchariflorus genome sequence, Miscanthus RNAseq data
Collaborator Contribution Miscanthus sinensis genome sequence (https://phytozome.jgi.doe.gov/pz/portal.html#!info?alias=Org_Msinensis_er), Miscanthus RNAseq data, Miscanthus molecular markers
Impact Mitros et al. Genome biology of the paleotetraploid perennial biomass crop Miscanthus. Nat Commun 11, 5442 (2020). https://doi.org/10.1038/s41467-020-18923-6 De Vega J, Donnison I, Dyer S, Farrar K. Draft genome assembly of the biofuel grass crop Miscanthus sacchariflorus. F1000Res. 2021 Jan 18;10:29. doi: 10.12688/f1000research.44714.1. PMID: 33732433; PMCID: PMC7921889.
Start Year 2014
 
Description Miscanthus genome, pangenome 
Organisation Teagasc
Country Ireland 
Sector Public 
PI Contribution Miscanthus sacchariflorus genome sequence, Miscanthus RNAseq data
Collaborator Contribution Miscanthus sinensis genome sequence (https://phytozome.jgi.doe.gov/pz/portal.html#!info?alias=Org_Msinensis_er), Miscanthus RNAseq data, Miscanthus molecular markers
Impact Mitros et al. Genome biology of the paleotetraploid perennial biomass crop Miscanthus. Nat Commun 11, 5442 (2020). https://doi.org/10.1038/s41467-020-18923-6 De Vega J, Donnison I, Dyer S, Farrar K. Draft genome assembly of the biofuel grass crop Miscanthus sacchariflorus. F1000Res. 2021 Jan 18;10:29. doi: 10.12688/f1000research.44714.1. PMID: 33732433; PMCID: PMC7921889.
Start Year 2014
 
Description Miscanthus genome, pangenome 
Organisation U.S. Department of Energy Joint Genome Institute
Country United States 
Sector Public 
PI Contribution Miscanthus sacchariflorus genome sequence, Miscanthus RNAseq data
Collaborator Contribution Miscanthus sinensis genome sequence (https://phytozome.jgi.doe.gov/pz/portal.html#!info?alias=Org_Msinensis_er), Miscanthus RNAseq data, Miscanthus molecular markers
Impact Mitros et al. Genome biology of the paleotetraploid perennial biomass crop Miscanthus. Nat Commun 11, 5442 (2020). https://doi.org/10.1038/s41467-020-18923-6 De Vega J, Donnison I, Dyer S, Farrar K. Draft genome assembly of the biofuel grass crop Miscanthus sacchariflorus. F1000Res. 2021 Jan 18;10:29. doi: 10.12688/f1000research.44714.1. PMID: 33732433; PMCID: PMC7921889.
Start Year 2014
 
Description Miscanthus genome, pangenome 
Organisation University of California, Berkeley
Country United States 
Sector Academic/University 
PI Contribution Miscanthus sacchariflorus genome sequence, Miscanthus RNAseq data
Collaborator Contribution Miscanthus sinensis genome sequence (https://phytozome.jgi.doe.gov/pz/portal.html#!info?alias=Org_Msinensis_er), Miscanthus RNAseq data, Miscanthus molecular markers
Impact Mitros et al. Genome biology of the paleotetraploid perennial biomass crop Miscanthus. Nat Commun 11, 5442 (2020). https://doi.org/10.1038/s41467-020-18923-6 De Vega J, Donnison I, Dyer S, Farrar K. Draft genome assembly of the biofuel grass crop Miscanthus sacchariflorus. F1000Res. 2021 Jan 18;10:29. doi: 10.12688/f1000research.44714.1. PMID: 33732433; PMCID: PMC7921889.
Start Year 2014
 
Description Miscanthus genome, pangenome 
Organisation University of Illinois at Urbana-Champaign
Country United States 
Sector Academic/University 
PI Contribution Miscanthus sacchariflorus genome sequence, Miscanthus RNAseq data
Collaborator Contribution Miscanthus sinensis genome sequence (https://phytozome.jgi.doe.gov/pz/portal.html#!info?alias=Org_Msinensis_er), Miscanthus RNAseq data, Miscanthus molecular markers
Impact Mitros et al. Genome biology of the paleotetraploid perennial biomass crop Miscanthus. Nat Commun 11, 5442 (2020). https://doi.org/10.1038/s41467-020-18923-6 De Vega J, Donnison I, Dyer S, Farrar K. Draft genome assembly of the biofuel grass crop Miscanthus sacchariflorus. F1000Res. 2021 Jan 18;10:29. doi: 10.12688/f1000research.44714.1. PMID: 33732433; PMCID: PMC7921889.
Start Year 2014
 
Description RBG Kew 
Organisation Royal Botanic Gardens, Kew
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Joint PhD studentship
Collaborator Contribution Joint PhD studentship
Impact Joint PhD studentship
Start Year 2021
 
Description RGBKew - EI fonio reference genome 
Organisation Earlham Institute
Country United Kingdom 
Sector Academic/University 
PI Contribution We characterise and provide materials for generation of genomic data (HiFi and Omni-C) for black fonio species. We provide staff time to analyse the data.
Collaborator Contribution EI will optimise methodologies for black fonio and generate data for RBGKew materials. EI will advise on data processing and analyses.
Impact Collaboration agreement. Short read data sequencing data for black fonio.
Start Year 2023
 
Description Syngenta collaboration 
Organisation Syngenta International AG
Country Switzerland 
Sector Private 
PI Contribution Facilitating regular meetings between EI and Syngenta researchers to develop 2 new collaborative projects.
Collaborator Contribution Attended industry Seminar. Arranged introduction to further teams at Syngenta.
Impact None yet.
Start Year 2023
 
Description Tozer Seeds Knowledge Transfer Partnership 
Organisation Tozer Seeds
Country United Kingdom 
Sector Private 
PI Contribution Develop a project idea for a Knowledge Transfer Partnership (KTP) with Tozer Seeds, management of the application process and negotiation of IP and terms. The KTP will help Tozer to develop internal capacity to analyse genomic data for accelerated breeding. This collaboration began as a service provided by NBRI1 and JV in 2022, after which the BDI team assisted in developing it further into the KTP.
Collaborator Contribution Tozer co-applied for KTP with EI and will be providing funding and in-kind support.
Impact Application for a KTP submitted in November 2023. Earlham Institute gaining status as a KTN Knowledge Base. KTP was funded and started in July 2024 and will run till December 2026 (30 months)
Start Year 2022
 
Description Tropic 
Organisation Tropic Biosciences Ltd
Country United Kingdom 
Sector Private 
PI Contribution We continue our collaboration with the biotech company Tropic related to their interest in improving copy number variation screening in order to further improve quality control in precision breeding of clonally propagated crops, such as banana. We contributed - Oxford Nanopore genome and epigenome sequencing Protocol and the variation analysis pipeline
Collaborator Contribution Expertise in banana cell biology, tissue culture, micropropagation and production, samples of proprietary elite banana embryogenic cell lines developed at Tropic, expertise in genomic/bioinformatic analysis
Impact Oxford Nanopore genome and epigenome sequencing Protocols New datasets
Start Year 2023
 
Title Software Architectural Design of COPO 
Description I have been responsible for the overall design and delivery of many new features in COPO over the past 12 months. Please see recent software output entries for further details. 
Type Of Technology New/Improved Technique/Technology 
Year Produced 2023 
Open Source License? Yes  
Impact The overall growth of COPO as a service 
 
Description A method for assembling the genome of a non-model organism 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact We supported Dr Camilla Ryan in writing a technical led blog about her methods for assembling the genome of a non-model organism, supporting the Decoding Biodiversity research programme (WP2). As part of the technical series this received good level of readership and engagement online.
Year(s) Of Engagement Activity 2024
URL https://www.earlham.ac.uk/articles/method-assembling-genome-non-model-organism
 
Description A presentation on natural product drug discovery and bioactive molecules (including DECODE Asteraceae research) was delivered to a group of students from Colby College, USA. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact Increased interest and awareness of the role of bioactive molecules from plants and technologies to source these, which stimulated questions and discussion on the subject.
Year(s) Of Engagement Activity 2025
 
Description A talk was given on natural product drug discovery and bioactive molecules (including DECODE Asteraceae research) to a group of Chief Medical Officers from a range of international companies 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Increased interest and awareness of the role of bioactive molecules from plants and advanced technologies to sustainably source these, which stimulated questions and discussion on the subject.
Year(s) Of Engagement Activity 2025
 
Description Agri-Tech E REAP conference 2023 (09/11/2023) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Attended Agri-Tech E's annual event REAP and took researchers from the DECODE and CELLGEN ISPs. Set up an EI exhibition stand, assisted JA with his talk and assisting with networking on the day. The exhibition stand was comprised of talking points to showcase the EI researchers and their work attending Agri-Tech E. This included:
- a lego sequencer to demonstrate the genomics work being undertaken in clonal crops in DECODE and forage crops in CELLGEN, and how sequencing is carried out by NBRI1
- a basket of clonal crops being researched in DECODE
- wheat seedlings from lines being researched in DECODE
- a short presentation to compliment JA's talk, demonstrating how image analysis is used to determine diversity of seed packets
Year(s) Of Engagement Activity 2023
URL https://www.agri-tech-e.co.uk/microsite-page/reap-2023/
 
Description Attendance at Biocuration 2023 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Attended conference to network and find out latest developments.
Year(s) Of Engagement Activity 2023
 
Description Big Data Workshop 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Gave talk on data management to PhD students.
Year(s) Of Engagement Activity 2023
 
Description Biofair Roadshow EI 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Contributed thoughts to fact finding workshop
Year(s) Of Engagement Activity 2023
 
Description British Herbs Association Technical Meeting Talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact A BBSRC-iCASE PhD project update and plan talk to the British Herbs Association. This group consists primarily of growers and agronomists, but is also attended by breeders and other stakeholders. 15 minute presentation, follow-up questions and a networking lunch. Primary objective was to get feedback from growers on traits of interest for the project. Also to open a dialogue with British Herbs regarding closer involvement in the project.
Year(s) Of Engagement Activity 2024
 
Description Building capacity and resources for genomic prediction in forage grass and legume breeding 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact The workshop brought together a diverse group of researchers, practitioners, and stakeholders to exchange information and foster collaboration in the vital field of forage research. The project
integrated experts from Earlham Institute in the UK and Alliance of Bioversity International and CIAT
who collaborate on the application of genomic tools into the Tropical Forages breeding program.
Year(s) Of Engagement Activity 2024
URL https://hdl.handle.net/10568/170303
 
Description Characterising gene function research project page 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Published a research project page detailing aims and activities from WP2 of Decoding Biodiversity research programme. The page is used for signposting people to more information about the work package.
Year(s) Of Engagement Activity 2024,2025
URL https://www.earlham.ac.uk/research-project/characterising-gene-function-biosynthetic-pathways-and-va...
 
Description DBT Agri-Tech Investment Specialist visit to Norwich Research Park (06/02/2024) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Policymakers/politicians
Results and Impact A member from each NBI gave an introductory talk to the specialist on agri-tech development at their institute, to give the specialist an understanding of the research ongoing on the park.
Year(s) Of Engagement Activity 2024
 
Description DSW Annual Meeting 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Coordinated a science showcase entitled 'Cutting-edge wheat and pathogen (pan) genomics' at the annual DSW all-hands meeting.
Year(s) Of Engagement Activity 2025
 
Description Digital Twins in bioscience, environmental and medical science 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Digital twins (DT) and their application are an area of growing interest within the bioscience, environmental and medical science research and innovation community. BBSRC, NERC, MRC and DTNet+ jointly ran a hybrid community workshop focussed on digital twins in bioscience, environmental and medical science on Wednesday 18 September 2024 at Rothamsted Conference Centre. The event aimed to create a better shared understanding of the DT landscape as it relates to the bioscience, environmental and medical science research and innovation communities, including better insights into the discipline-specific opportunities and challenges together with opportunities to network as a community.
Year(s) Of Engagement Activity 2024
URL https://engagementhub.ukri.org/bbsrc-research-strategy-and-programmes/digital-twins-workshop/
 
Description EI Innovate 2023 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact A presentation by Dr Melissa Salmon at EI Innovate, an event for knowledge exchange between academics and industry, about the discovery of bioactive metabolites from UK flora and methods for their bioproduction. This was followed by a number of questions and discussion with Dr. Salmon.
Year(s) Of Engagement Activity 2023
 
Description EI Innovate annual stakeholder engagement event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact EI Innovate is an annual engagement event that provides insight into the Earlham Institute's research, exploring opportunities for innovation and collaboration. Specialising in agri-food, biotech, med-tech and public health, we have a wealth of experience collaborating with others to develop potential solutions to urgent industrial and societal challenges.

EI Innovate events foster exciting and valuable conversations between academia and industry. An example of an exciting collaboration that resulted from a previous EI Innovate is the Hybrid Wheat Initiative, which connects 25 breeding companies and research institutes worldwide, to resolve the critical challenge of hybrid wheat.

In 2023, we showcased our two new strategic programmes of research - Cellular Genomics and Decoding Biodiversity - and two National Bioscience Research Infrastructures (NBRIs) - Transformative Genomics and the Earlham Biofoundry.

The programme included talks about Earlham expertise and capabilities, examples of collaborations, panel discussions, Innovation Showcase, exhibition, tours of the two National Bioscience Research Infrastructures (NBRIs) - Transformative Genomics and the Earlham Biofoundry, and networking.
Year(s) Of Engagement Activity 2019,2020,2021,2022,2023
URL https://www.earlham.ac.uk/events/ei-innovate-2023
 
Description EI Seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Gave EI seminar
Year(s) Of Engagement Activity 2024
 
Description ERGA data management training (Poland) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Gave talk about data management and COPO along with reps from ENA at a workshop in Poland
Year(s) Of Engagement Activity 2025
 
Description Elected to Royal Norfolk Agricultural Agricultural Association Council 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact The RNAA Council is a volunteer body and has supervisory control over both the property and the general policy of the Association. It provides a useful check and balance to the strategic direction of the Association. Council comprises up to 48 elected members and meets twice a year, usually in the Spring and Autumn. Council members are expected to take an active interest in the development of the Association.
Year(s) Of Engagement Activity 2023
 
Description Elixir UK all hands - Norwich 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Engaged in networking group discussions
Year(s) Of Engagement Activity 2023
 
Description Elixir UK all-hands 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Took part in various sessions and a poster session at this UK based meeting.
Year(s) Of Engagement Activity 2024
 
Description Elixir all-hands Dublin 2023 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presented a poster, and had discussion regarding development of ROCrate which led to several hackathons.
Year(s) Of Engagement Activity 2023
 
Description Elixir all-hands Uppsalla 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presented 2 posters at all-hands meeting
Year(s) Of Engagement Activity 2023
 
Description Equitable Practise in Evolution Training - Applying the Equity Compass 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact This course helped me to reflect on and develop equitable and inclusive practice. It involved two in-person sessions (13 February 2024 & 13 March 2024) at the Earlham Institute to introduce The Equity Compass, a tool to address ongoing inequalities in STEM communication. These sessions were supported by a three-week online/self-motivated course via FutureLearn.
Year(s) Of Engagement Activity 2024
 
Description FLF Development Network - Crucible 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact An interdisciplinary, cross-sector event that fosters collaborations between researchers and innovators on the Pathways FLF Development Network program.
Year(s) Of Engagement Activity 2024
 
Description FLF Development Network - Crucible in Cardiff 21-22 March 2024 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact An interdisciplinary, cross-sector event that fosters collaborations between researchers and innovators on the Pathways FLF Development Network program.
Year(s) Of Engagement Activity 2024
 
Description FLF Development Network - Leadership Retreat 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact A Pathways FLF Development event to give insights into navigating the process of leading research and innovation programmes, and managing teams.
Year(s) Of Engagement Activity 2024
 
Description FTMA visit of WorldFish at EI and training of partners from the Lake Victoria Fisheries Organisation 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Meeting at the Earlham Institute with WorldFish researchers to develop the report for the Lake Victoria Fisheries Organization to inform policy development for the sustainable exploitation of tilapia. Training of representatives from Uganda, Kenya, and Tanzania on the bioinformatics for population genetics
Year(s) Of Engagement Activity 2023
 
Description Genetic integrity needed for Biodiversity Net Gain to flower 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact An article with PhD researcher Jonathan Ashworth, discussing his work in biodiversity genomics of wildflower seeds, and the link to Biodiversity Net Gain. This gained a huge amount of engagement online, and led to interested collaborators reaching out to Jose and Jonathan, and further work with the Business Development and Impact team signing agreements to work together. The Eden project (collaborators on the research) also reached out to ask to include it in their membership magazine.
Year(s) Of Engagement Activity 2024
URL https://www.earlham.ac.uk/articles/genetic-integrity-needed-biodiversity-net-gain-flower
 
Description Genomic resources to help boost climate resilience of fisheries 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact We issued a press release on new research around genomic resources for aquaculture breeders, which could support the development of greater resilience. The story had almost 5,000 impressions and around 75 engagements on social media, including from accounts for people and partners based outside the UK.
Year(s) Of Engagement Activity 2023
URL https://www.earlham.ac.uk/news/genomic-resources-help-boost-climate-resilience-fisheries
 
Description IBERS visit 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact A group of EI staff visited IBERS in Aberystwyth from 19-21 July 2023 (Jose De Vega, Anthony Hall, Seanna McTaggart, Camilla Ryan, Christine Fosker) to discuss the DECODE ISP, find opportunties for collaboration and tour IBERS and the biorefinery.
Year(s) Of Engagement Activity 2023
 
Description ISP all hands meetings FTMA4 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact ISP all hands meeting allow the interaction amongst all the work package members. In addition to project and impact progress updates, workshops are held to drive discussion in areas such as IDEA, policy impact, futher funding opportunities and more.
Year(s) Of Engagement Activity 2023,2024
 
Description Image Processing Carpentries 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Devlivered Training
Year(s) Of Engagement Activity 2023
 
Description Invited talk Syngenta 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Presentation of work on Pangenomes and work within DECODE Title:Why one genome just isn't enough:
How multiple wheat genomes are changing our understanding of plant evolution.
Year(s) Of Engagement Activity 2023
 
Description Invited to participate in Royal Society 'Transforming Our Future' workshop, 'Innovating Agriculture' 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact This meeting explored the agricultural science and innovation that is transforming the future of food and farming to meet rising production and environmental demands. The agricultural sector needs to meet the challenge of producing more food to meet rising demand whilst also achieving environmental targets. This two-day conference examined the science and innovation aiming to transform the future of food and farming.

The event brought together stakeholders from across industry, academia, government and the wider agricultural community to address three key areas: increasing sustainable yields, improving input efficiency and developing novel food production systems. Panel discussions considered how best to support and fund innovation in food and agriculture, and how to accelerate translation and take-up of new ideas.
Year(s) Of Engagement Activity 2024
URL https://royalsociety.org/science-events-and-lectures/2024/06/agriculture-tof/?gad_source=1&gclid=Cjw...
 
Description Key tilapia genome offers boost to global food security - Tarang Mehta, Graham Etherington, Will Nash, Adam Ciezarek 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact News story to highlight a new publication from EI researchers on reference genome for a key aquaculture species, designed to reach breeders, industry, and academics working in this space. Positive trade media coverage, as well as promotion from project collaborators, helped this news to reach a wide audience and enhance EI's reputation.
Year(s) Of Engagement Activity 2023
URL https://www.earlham.ac.uk/news/key-tilapia-genome-offers-boost-global-food-security
 
Description Keynote, UK Legume Conference 2024; "Adaptations and admixture in common bean and genomics for breeding" 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Keynote speaker in the Genomics and Genetics session of the UK Legume Conference in Reading, 14-15 Feb 2024
Year(s) Of Engagement Activity 2024
URL https://uklrc.org/uklrc2024/
 
Description Lecture delivered on natural product drug discovery and bioactive molecules (including DECODE Asteraceae research) for the RBG Kew / Royal Holloway University of London MSc titled 'Global Health: Food security, Sustainability and Biodiversity' 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Increased interest and awareness of the role of bioactive molecules from plants and advanced technologies to source these, which stimulated questions and discussion on the subject. Students expressed interest in applying for MSc projects on this topic.
Year(s) Of Engagement Activity 2024
 
Description Meeting with Prof Gideon Henderson, DEFRA Chief Scientific Adviser 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Prof Gideon Henderson visited the Earlham Institute and discussed a range of DEFRA related research activity and innovation. He invited EI to have follow up engagement with DEFRA officials leading relevant policy and regulatory work.
Year(s) Of Engagement Activity 2024
 
Description Meeting with the UK Science & Innovation team from the UK Embassy in Mexico 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact The Science & Innovation Network (SIN) in Mexico works to encourage strategic relationships with local and national government and academic institutions between the UK and Mexico.
Year(s) Of Engagement Activity 2014
 
Description Monogram 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The Monogram Network consists of UK based researchers with an active interest in small grain cereal and grass (including the C4 energy grasses) research. I attended the annual conference at the University of Reading with Jon Wright, Anthony Hall, Lucy Mahony.
Year(s) Of Engagement Activity 2023
 
Description Multigenome Brassica Project (MGBP) Steering Committee Meeting 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Attended Annual MGBP Steering Committee meeting at PAG30 to discuss future opportunities to work together.
Year(s) Of Engagement Activity 2023
 
Description Oral Presentation - Regulatory networks evolution underlying the rapid diversification of cichlids fishes in the Great African Lakes - Tarang Mehta 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited presentation at the Society for Molecular Biology and Evolution Annual Meeting (Ferrara Italy)
Year(s) Of Engagement Activity 2023
URL https://www.smbe2023.org/
 
Description PAG Talk 2024- Wheat Genomics to Breeding session 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Sequencing, assembling and annotating key cultivars and representatives of 7 wheat sub-populations
Wheat diversity can be split into 7 subpopulations. Here I will give an update on work as part of the Design Sustainable Wheat programme to sequencing, assembly and annotating these. How these and other data sets can be added to improve the utility of existing data.
Year(s) Of Engagement Activity 2024
 
Description PAG2024 Trticeae Genetics and Genomics 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Title: Using pangenomes in Anger to Reduce reference bias in transcriptomic experiments
Year(s) Of Engagement Activity 2024
 
Description PCA Core Network Participant Meeting (CPN) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Made connections and panned for future grant submission.
Year(s) Of Engagement Activity 2023
 
Description Pan-European project generates genomes showcasing continent's rich biodiversity 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A news story supporting the European Reference Genome Atlas Pilot Project. The story showcases the success of the pilot project and highlights the wide-ranging involvement from the Earlham Institute including the Technical Genomics, Haerty, Anthony Hall, and Neil Hall Groups, as well as the role of the National Bioscience Research Infrastructure in Transformative Genomics.
Year(s) Of Engagement Activity 2024
URL https://www.earlham.ac.uk/news/pan-european-project-generates-genomes-showcasing-continents-rich-bio...
 
Description Pan-Pooideae Meeting at PAG32 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Workshop at PAG32 to discuss the international Pan-Pooideae network. Overview of current research proposals and plans for next meeting.
Year(s) Of Engagement Activity 2025
 
Description Pint of Science 2023 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation by PhD student in Norwich as part of the National Pint of Science Festival 2023 followed by questions and discussion.
Year(s) Of Engagement Activity 2023
 
Description Plant Animal Genome Conference, San Diego 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presented a poster on 'Identifying Consensus and Cultivar-Specific Gene Networks within the Wheat Pan-Transcriptome'. Attended with Anthony Hall, Jon Wright (poster on A High-Quality Genome of Paragon: A Keystone for UK Wheat Breeding), Lucy Mahony (poster on Decoding the Regulatory Regions of Wheat).
Year(s) Of Engagement Activity 2023
 
Description Plant Pangenome Working Group 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The aim of this group is to bring together a small group of researchers with overlapping expertise in wheat genomics and pangenome architecture to identify possible strategies and approaches that will enable a high resolution pangenome reference for the wheat community. We held an initial meeting at PAG32 in SanDiego, Jan 2025 to gauge interest, exchange experiences and plan further virtual meetings.
Year(s) Of Engagement Activity 2025
 
Description Presentation at 2025 Legume Research Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact I delivered a 10 minute presentation with 5 minutes for questions, which allowed for futher discussion. This then resulted in discussions of future work.
Year(s) Of Engagement Activity 2025
 
Description Presentation at the Innovation Showcase during EI Innovate 2023 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact As part of the EI Innovate event in 2023, BDI team featured winners of the internal KEC Awards as part of the Innovation Showcase. JC, TB, JdV, WH, AH, JL presented their projects showcasing their KEC work - developing a spinout, a substantial collaboration, or a knowledge exchange activity with industry.

EI Innovate is an annual engagement event that provides insight into the Earlham Institute's research, exploring opportunities for innovation and collaboration. Specialising in agri-food, biotech, med-tech and public health, we have a wealth of experience collaborating with others to develop potential solutions to urgent industrial and societal challenges.
Year(s) Of Engagement Activity 2023
URL https://www.earlham.ac.uk/events/ei-innovate-2023
 
Description Presentation given to the 'University of Bath placement conference' for students and staff of the Chemistry Department 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Undergraduate students
Results and Impact The aim of the presentation was to outline the research being undertaken by Rachel Wong (MChem undergraduate intern) who is working on the DECODE project at The Royal Botanic Gardens Kew (lead supervisor Dr Melanie Howes). During the presentation she outlined the project, highlighting the importance of natural product chemistry and plant bioactives relating to the DECODE project. The presentation generated a lot of interest and questions leading to an increased interest in this research topic.
Year(s) Of Engagement Activity 2024
 
Description Presented at Monogram conference 2023 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact I presented a talk about using HiFi and OmniC reads to create a high quality haplotype aware assembly of Urochloa decumbens. The talk title was 'Double trouble - assembling the complex allelic diversity in outcrossed tetraploid Urochloa decumbens.'. It reached the conference attendees however I am not sure exaclty how many people that was - a lecture theatre full.
Year(s) Of Engagement Activity 2023
URL https://research.reading.ac.uk/monogram-2023/
 
Description Presented data management talk on single cell RNA course 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact half hour section as part of the course to train early career researchers about best practice in research data management
Year(s) Of Engagement Activity 2024
 
Description Project Meeting at Syngenta Site 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Members of the Anthony Hall Group (AH, RLRP) and TraitSeq (JC, VD) met with collaborators Melissa Brazier-Hicks, Irene Gonzalez-Thuillier and Victor Labonia from Syngenta to discuss current collaboration, tour facilities and meet staff for discussions.
Year(s) Of Engagement Activity 2023
 
Description Quarterly Institution Strategic Programme Work package meetings 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact ISP work package meetings are hybrid and open to and involve all participants in the ISPs, including partners. The meetings include 1-3 oral presentations showcasing ongoing work and roundtable discussions on successes, barriers, and opportunities.
Year(s) Of Engagement Activity 2023,2024,2025
 
Description Revealing the genes that build plant bioactives 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Supporting the Decoding Biodiversity research programme, we wrote an article with Mel Salmon of the Patron Group about their work revealing the genes that build plant bioactives. This includes reference to our partnership with RBG Kew. This was also used later to promote activities at the 2025 Norwich Science Festival.
Year(s) Of Engagement Activity 2024
URL https://www.earlham.ac.uk/articles/revealing-genes-build-plant-bioactives
 
Description Royal Norfolk Agricultural Show - Stewarding 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Assistant Head Steward helping RNAA coordinate STEMM village, AgriTechE and new machinery/innovations area at the Royal Norfolk Show, over 2days.
Year(s) Of Engagement Activity 2023
URL https://www.royalnorfolkshow.co.uk/
 
Description SAB Networking Dinners (x2) 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact 2 dinners during which I networked with senior advisory board of EI, to elucidate them on COPO
Year(s) Of Engagement Activity 2023
 
Description SAB Poster Session 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presented COPO at a poster session for the 2023 SAB
Year(s) Of Engagement Activity 2023
 
Description Save the Banana! at the Norwich Science Festival 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact We took an activity aimed at 4-10 year old children to Norwich Science Festival 2024. This activity was based around the De Vega group's work on banana genomics. Over the three days we attended the festival we engaged with more than 1000 children and feedback (measured via feedback forms) was very positive. Many participants did not know the Cavendish banana was under threat.
Year(s) Of Engagement Activity 2024
 
Description Science Day at Notre Dame Prep School 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Delivered science activities as part of Sustainable Science Day at Notre Dame Prep School, Norwich. 120 pupils from Year 1 to Year 6 participated in science activities related to the DECODE ISP on the topics of "Save the Banana" (an activity previously run at the Norwich Science Festival) and "Making Medicines in Plants". Pupils listened to a presentation introducing the science, and then worked their way around the activities, filling in their results in a "Lab Notebook".
The school reported that the children and teaching staff found the activities engaging and inspiring and are keen to hold another science day in the next academic year.
Melissa Salmon organised and coordinated the Science Day and produced the lab notebooks and activity sheets for "Making Medicines in Plants"
Sarah Guiziou, Daria Golubova and Carolina Olave-Achury volunteered to help with delivering the activities.
Year(s) Of Engagement Activity 2024
 
Description Scilifelab presentation meeting 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Demonstration of the efficacy of COPO as a brokering solution for Scilifelab.
Year(s) Of Engagement Activity 2023
 
Description Software Carpentries 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Delivered training
Year(s) Of Engagement Activity 2023
 
Description Syngenta Product Safety and Biological Sciences External Collaboration Event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact This event is a forum to present academic research to peers and a wide cross-section of Syngenta colleagues. Josh Colmer and I presented an interactive poster and JC gave a flash talk. We were awarded best poster.
Year(s) Of Engagement Activity 2023
 
Description Talk - Postgrad Data Literacy 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Part of an annual PGR education programme
Year(s) Of Engagement Activity 2023
 
Description Talk for UEA Pharmacology student visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Undergraduate students
Results and Impact 15 masters students from UEA pharmacology department visited the institute for a tour and talks about the benefits of doing a PhD and a selection of talks by PIs and a post-doc to highlight the research being conducted at EI. Many of the students asked questions and provided positive feedback.
Year(s) Of Engagement Activity 2024
 
Description Talk in Big Data training session 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Presented best practice in current research data management technology to UEA/NRP PhD students.
Year(s) Of Engagement Activity 2024
 
Description Talk on natural product drug discovery and bioactive molecules (including DECODE Asteraceae research) delivered to a group from the u3a (a UK-wide collection of charities that provide learning opportunities for those no longer in work) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Increased interest and awareness of the role of bioactive molecules from plants and technologies to source these, which stimulated questions and discussion on the subject.
Year(s) Of Engagement Activity 2024
 
Description Talk to PHD DTP cohort on data management and COPO 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact As part of a day of training, I talked for an hour about research data management, FAIR and the importance of these
Year(s) Of Engagement Activity 2025
 
Description Technical blog posts 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Three technical blog post tutorials designed to educate other researchers on how to produce various data visualisations in R.
Year(s) Of Engagement Activity 2023
URL https://www.earlham.ac.uk/articles/plotting-proportional-data-nested-circles-r
 
Description The fish, the fungus, the grass, the bee - and the brassica 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Article on Earlham Institute's membership of ERGA, gaining positive feedback and shares from external organisations.

As we live through the planet's sixth mass extinction event, the Earlham Institute has joined the European Reference Genome Atlas (ERGA), a ground-breaking network of researchers across Europe documenting our vanishing lifeforms.

ERGA is a continent-wide response to the threat to diversity, collecting and sequencing the genomes of all European eukaryotes to better understand them for the future. It is part of the wider Earth Biogenome Project.
Year(s) Of Engagement Activity 2024
URL https://www.earlham.ac.uk/articles/fish-fungus-grass-bee-and-brassica
 
Description Trip to Brussels for PROGRACE/EMPHASIS/forEVA as invited speaker 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The joint PRO-GRACE/EMPHASIS Policy Symposium and Workshop on Plant Genetic Resources and Phenotyping was held in Brussels on 27-28 June 2024. around 30-50 people attended. This sparked discussions in how to properly store data and other plant genetic -related discussions
Year(s) Of Engagement Activity 2024
URL https://grace-ri.eu/pro-grace/news-events
 
Description Virtual presentation at BBSRC funded UK-Argentina wheat workshop in Buenos Aires 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited talk on wheat genomics. The goal of the workshop was to facilitate future UK-Argentina cooperation around wheat.
Year(s) Of Engagement Activity 2023
 
Description Visit and workshop of EI researchers to IBERS. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Crop Genomics - Earlham Institute visit to IBERS 20th July 2023
Year(s) Of Engagement Activity 2024
 
Description Wendling Beck DEFRA Test & Trial workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact A series of three workshops lead by the Wendling Beck Environment Project discussing biodiversity monitoring with ecologists, naturalist groups, farmers and landowners. I had a range of discussions with practitioners engaged in developing and testing technologies for monitoring and recording biodiversity trends.
Year(s) Of Engagement Activity 2024,2025
URL https://www.wendlingbeck.org/
 
Description Workshop UK:BalticWheat workshop 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Gave a talk at the workshop "Why multiple wheat genomes are important"
Year(s) Of Engagement Activity 2023
 
Description Workshop between Earlham and Eagle Genomics 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact A visit 7 Earlham colleagues to Eagle Genomics in London to build a collaborative framework between Eagle and Earlham, as part of collaborations with DECODE and CELLGEN ISPs. Key areas of the framework include IP management, software licensing; terms of access to EI tools and data; standardisation of tools and data to enable commercialisation; and areas of joint research interests resulting in publications (animal health and probiotics, soil health). This visit was funded through the BBSRC FTMA4.
Year(s) Of Engagement Activity 2023
 
Description https://www.earlham.ac.uk/news/earlham-institute-BBSRC-funding-award-2023 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact We issued a press release to mark the 5-year funding award from BBSRC, which supports the Earlham Institute, ISPs, and NBRIs. We secured widespread regional media coverage, including BBC Look East and online, ITV Anglia, and the EDP. The feedback from BBSRC on this coverage was very positive, particularly due to competing stories on life science funding. The launch campaign received around 28.5k impressions and 1,000 engagements across social media platforms, with the launch tweet achieving 330 engagements on its own. The majority of ISP partners engaged either by sharing ours posts or publishing their own messages, which included Kew Science, UK CEH, Eagle Genomics, and PacBio.
Year(s) Of Engagement Activity 2023
URL https://www.earlham.ac.uk/news/earlham-institute-BBSRC-funding-award-2023