High Containment

Lead Research Organisation: The Pirbright Institute
Department Name: UNLISTED

Abstract

The Pirbright Institute is a front-line national capability in the response to incursions of exotic viral pathogens in the UK and is a key player in worldwide research of methods to predict, detect and control outbreaks of disease. To achieve this vital role there is a requirement to provide infrastructure and highly specialised expertise across a variety of disciplines, underpinning the science outlined in the institute’s new BBSRC Institute Strategic Programme Grants (ISPG). The primary high containment facilities at The Pirbright Institute are the Animal Isolation units, which enable studies of viral infection in natural ruminant hosts (cattle, sheep, pigs, goats) and the Plowright building, a state of the art laboratory facility housing opened in 2015. These facilities enable studies to be carried out on the most infectious viral diseases of animals known, including foot and mouth disease virus and African swine fever virus. In addition, the Plowright Laboratory is also increasingly used in the study of zoonotic viruses and those that are transmitted between humans by insect vectors. This broadening of research scope is a key aspect to strategic planning and reflects an increasing integration between medical and veterinary research at the site.

Organisations

Publications

10 25 50
 
Title E17 Art Trail - STEAM theme (Jennifer Simpson) 
Description Laboratory of Tiny Things installation which ran in London for three weeks. Open to the general public. 
Type Of Art Image 
Year Produced 2017 
Impact No known impact 
 
Title The Pathologist - Through the Looking Glass (Jennifer Simpson) 
Description Article showcasing a gallery of beautiful images from all walks of laboratory medicine 
Type Of Art Image 
Year Produced 2017 
Impact No impacts known 
 
Description The key development within high containment science at The Pirbright Institute is that of cutting edge containment facilities that allow handling of viruses with in a safe manner for the user and environment and with minimal interruptions to work. In the two years since the project was initiated, downtime for science has been limited to planned preventative maintenance only in the BBSRC National Virology Centre (Plowright Building) and this has resulted in the production of >60 peer-reviewed publications by our scientists. Our scientists have also delivered over 150 engagement activities, increasing the profile of these studies and providing evidence for their importance within a wider funding context. In year two there was an interruption to use of the contained animal facilities, but this had minimal impact on users through planned rescheduling of engineering maintenance and did not affect strategic programme grant targets. We have worked closely with HSE and remain in full compliance with our SAPO license and other health and safety law. Meetings with both the Home Office and NC3Rs were recorded within the reporting period. In the first year of the High Containment grant, more than 50 workers received biosecurity training alongside a range of international activities that included membership of BSL4Znet, a network of high containment laboratories and specific partnerships with Ethiopia, Tanzania and Argentina. This ranged from advice on infrastructure planning through to formal processes to maintain a high level of health and safety and biosecurity. Discussions on access and collaboration have been held with a range of partners including University of Surrey, LSHTM, Glasgow University and the Roslin Institute. There was also an on demand response to ongoing outbreaks of African swine fever virus and bluetongue virus, both of which currently threaten the UK and horizon scanning for foot and mouth disease virus enabled by the high containment infrastructure and our retention of UK reference laboratories that operate at ISO/EC 17025 quality requirements. The Institute website is in the process of being revised to improve the public understanding of how containment facilities work and a range of outreach exercises have taken place that describe both our science and the role of infrastructure in enabling research. Dedicated videos have also been produced by our communications department with interviews from all the senior members of the CCG group. Infrastructure projects aimed at increasing flexibility in the use of contained animal facilities and in poultry research are continuing.
Exploitation Route Development of high containment infrastructure at Pirbright will include refurbishment of the virus isolation units for livestock which is in response to changing needs at the site. All of our main science programmes rely on both these and the Plowright building for their continuation and are an integral part of our response to virus incursion via reference laboratory functions. Hence, we will continue to learn and improve methods to minimise interruptions to science through advance planning of maintenance and to operate to the highest levels of health and safety and biosecurity. Through this process we will gain knowledge that will be disseminated to other infrastructure laboratories around the world through networking of senior CCG staff and site visits, complemented by outreach activities aimed at key stakeholder groups including the general public. This is a vital aspect of justifying what is a major investment for the UK.
Sectors Agriculture, Food and Drink

 
Description Minimal infrastructure downtime enabled by planned preventative maintenance on the BBSRC National Virology Centre (Plowright Building) and Virus Isolation Units for livestock has enabled both our research to be conducted under expected timescales and our response to potential incursions of foot and mouth disease virus (FMDV), bluetongue virus and African Swine fever virus to be planned with a high degree of reliability. Within the reporting year this has enabled a wide array of scientific outputs and the retention of the world reference laboratory for FMDV. These studies have also been enabled by the adoption of a health and safety and biosecurity approach which is commensurate with risk and which we will continue to modify according to our experience in running the facility.
First Year Of Impact 2017
Sector Agriculture, Food and Drink
Impact Types Societal,Economic,Policy & public services

 
Description BBSRC 18ALERT panel member
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact Provision of multi-user equipment to core facilities to enable BBSRC remit science. Part of the remit for this call was to allow shared access from other institutions, widening the impact of BBSRC investment.
 
Description BBSRC Bioimaging Review
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description Bioimaging Steering Group
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Membership of a guideline committee
Impact Improving access and efficient organization of Bioimaging for researchers at Pirbright
 
Description Contribution to a POSTnote on 'Reducing UK Antibiotic Use in Animals'
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description Drafted resolution that was endorsed by the World Assembly of Delegates (for the World Oganisation of Animal Health - OIE)
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact This policy document relates to one of the FMDV serotypes (called serotype C) which has disappeared for >10 years from the surveillance activities of the global OIE/FAO FMD Reference Laboratories (led by the Pirbright Institute). These laboratories now consider that the production of FMDV serotype C vaccines and their use in vaccine challenge experiments represent a risk of virus escape. Based on this evidence and concerns, this resolution urges that OIE Member Countries and vaccine manufacturers to stop the use of FMDV serotype C in vaccine challenge experiments and to consider halting the production of FMDV serotype C vaccines and inclusion in multivalent FMD vaccines except for holding in vaccine banks.
URL http://www.oie.int/fileadmin/Home/eng/About_us/docs/pdf/Session/2017/A_RESO_2017_Public.pdf
 
Description EFSA working group on lumpy skin disease
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
Impact Report to the European Commission on the spread and control of lumpy skin disease in the Balkans
URL http://www.efsa.europa.eu/en/efsajournal/pub/5176
 
Description EFSA working group on lumpy skin disease
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
Impact The models developed to describe the spread of lumpy skin disease virus (LSDV) within and between farms have been used to inform disease control policy following incursion of LSDV to south-eastern Europe. Specifically, the models were used to assess the impact of vaccination on disease spread. They were also used to investigate the duration of a vaccination campaign to prevent re-emergence of LSDV and to help design surveillance programmes to detect the re-emergence of the virus or its re-introduction from neighbouring countries. The results have been communicated to the European Commission and to affected countries via the European Food Safety Authority.
URL https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2018.5452
 
Description Inter-institute imaging network
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description Lumpy Skin Disease Control Strategy for Great Britain
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description Member of RMS EM Section committee
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact This committee informs the RMS on which areas to invest funds in regarding training, conferences, outreach events. RMS members are international.
 
Description Member of the British Society for Immunology Forum
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
URL https://www.immunology.org/
 
Description POSTnote Report on Climate and vector-diseases in humans in the UK
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
 
Description PPR DIVA Vaccine development . FAO/OIE in the meeting proceedings in December, 2018 recorded the future use of DIVA vaccine in the ongoing PPR eradication programme. This will be useful at least at the end phase of eradication to differentiate between vaccination and infection.As such few industries have contacted us to have the DIVA vaccine strains for commercialisation. Also some of the endemic countries are keen to have the strain for testing the DIVA vaccines in endemic settings.
Geographic Reach Multiple continents/international 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
 
Description PPR Global Research and Expertise Network (PPR GREN) membership (OIE/FAO)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description Publication policy document for core facilities - EM-UK
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact I am a founder member of the network created for electron microscopists within UK, EM-UK. The annual meeting is highly productive, and training and managing core facilities is regularly discussed. Recognition of these facilities is essential for their continued existence so we produced a generic document hosted on the RMS website which can be adopted by any core facility in any institution, and describes the publication policy which users had to adhere to. This has already raised the profile of core facilities around the country and is a successful outcome from the EM-UK meetings.
 
Description Royal Microscopical Society Microscopy Training Focussed Interest Group
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Royal Microscopical Society Training Focussed Interest Group
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact A review of the microscopy training courses available globally has been undertaken. We are in the process of collating and preparing a gap analysis. This will be used to guide RMS policy on training provided in the UK, both UK and international delegates.
 
Description University of Surrey MSc Vet microbiology - teaching (Jennifer Simpson)
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
Impact Two days of teaching practical microscopy, a useful cross disciplinary skill for many researchers
 
Description A One Health approach to pan-valent morbillivirus vaccines
Amount £773,237 (GBP)
Funding ID BB/R019843/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 05/2018 
End 03/2021
 
Description Active and passive Immunity induced by aerosols
Amount £100,000 (GBP)
Funding ID BB/R506448/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2017 
End 08/2021
 
Description BBSRC Industrial CASE (iCASE) studentship programme Oxford Interdisciplinary Bioscience Doctoral Training Partnership
Amount £80,000 (GBP)
Organisation University of Oxford 
Sector Academic/University
Country United Kingdom
Start 10/2019 
End 09/2023
 
Description BBSRC Newton Fund Swine and Poultry Research Initiative
Amount £865,623 (GBP)
Funding ID BB/R01275X/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2018 
End 06/2021
 
Description BBSRC responsive mode grant
Amount £367,000 (GBP)
Funding ID BB/P006841/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2017 
End 03/2019
 
Description BBSRC-iCASE
Amount £100,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2019 
End 09/2023
 
Description Biotechnology and Biological Sciences Research Council (BBSRC) and University of Oxford joint Doctoral Training Project
Amount £100,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 09/2018 
End 08/2022
 
Description Components of the Medea gene drive system in a mosquito Aedes aegypti
Amount £1,209,348 (GBP)
Funding ID BB/S001964/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 11/2018 
End 10/2021
 
Description DARPA PREEMPT
Amount $2,700,000 (USD)
Organisation Defense Advanced Research Projects Agency (DARPA) 
Sector Public
Country United States
Start 10/2018 
End 03/2022
 
Description Development of novel universal influenza vaccines
Amount £100,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2016 
End 10/2020
 
Description FLI- TPI joint PhD studentships Avian influenza immunology markers.
Amount £100,000 (GBP)
Organisation Friedrich Loeffler Institute 
Sector Public
Country Germany
Start 07/2018 
End 06/2022
 
Description Genomia Project Grant
Amount £174,052 (GBP)
Organisation Genomia fund 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2019 
End 01/2020
 
Description H2020 work programme topic 9 Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy, work topic SFS-10-2017 Research and approaches for emerging diseases in plants and terrestrial livestock
Amount € 5,986,250 (EUR)
Organisation European Commission H2020 
Sector Public
Country Belgium
Start 05/2018 
End 04/2023
 
Description International Workshops
Amount £10,000 (GBP)
Funding ID BB/R021198/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 05/2018 
End 05/2019
 
Description Newton Fund: UK-China-Philippines-Thailand Swine and Poultry Research Initiative
Amount £841,995 (GBP)
Funding ID BB/R012679/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 01/2018 
End 12/2020
 
Description Oxford DTP - Diamond Light Source/Harwell
Amount £100,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2018 
End 09/2022
 
Description Pirbright Institute PhD studentship
Amount £100,000 (GBP)
Organisation The Pirbright Institute 
Sector Academic/University
Country United Kingdom
Start 10/2018 
End 09/2022
 
Description Pirbright Institute PhD studentship
Amount £100,000 (GBP)
Organisation The Pirbright Institute 
Sector Academic/University
Country United Kingdom
Start 09/2018 
End 08/2022
 
Description Reducing the Economic and Zoonotic Impact of Avian Influenza (REZIAI): delivering novel vaccines and diagnostics from laboratory to the field.
Amount £400,000 (GBP)
Funding ID BB/S013792/1 
Organisation The Pirbright Institute 
Sector Academic/University
Country United Kingdom
Start 02/2019 
End 01/2021
 
Description SFS-10-2017 - Research and approaches for emerging diseases and pests in plants and terrestrial livestock: Addressing the dual emerging threats of African Swine Fever and Lumpy Skin Disease in Europe (DEFEND)
Amount € 5,986,250 (EUR)
Funding ID 773701 
Organisation European Commission H2020 
Sector Public
Country Belgium
Start 06/2018 
End 05/2023
 
Description The Global Challenges Research Fund
Amount £640,473 (GBP)
Organisation Research Councils UK (RCUK) 
Sector Public
Country United Kingdom
Start 04/2019 
End 03/2024
 
Description Workpackage within a Horzion 20:20 grant
Amount € 6,000,000 (EUR)
Funding ID EU project 727393 Horizon 20:20 PALE-Blue 
Organisation European Union 
Sector Public
Country European Union (EU)
Start 07/2017 
End 07/2021
 
Title Detection of HA antigens of avian influenza viruses 
Description Assay for detection of recombinant HVT expressing HA antigens of avian influenza viruses 
Type Of Material Technology assay or reagent 
Year Produced 2018 
Provided To Others? Yes  
Impact This new method will help to detect recombinant HVT vaccine expressing HA antigen in infected cell. 
 
Title Development of tetramers to study immune responses in pigs 
Description The pig is a natural and important host of influenza viruses and is physiologically more comparable to humans than other animal models in terms of size, respiratory tract biology and volume. It is also an important vector in the birds to human infection cycle. A major drawback of the current pig model is the inability to analyze antigen-specific CD8+ T-cell responses, which are critical to respiratory immunity. We addressed this knowledge gap using an established in-bred pig model with a high degree of genetic identity between individuals, including the MHC (Swine Leukocyte Antigen (SLA)) locus. We developed a toolset that included long-term in vitro pig T-cell culture and cloning and identification of novel immunodominant influenza-derived T-cell epitopes. We also generated structures of the two SLA class I molecules found in these animals presenting the immunodominant epitopes. These structures allowed definition of the primary anchor points for epitopes in the SLA binding groove and established SLA binding motifs that were used to successfully predict other influenza-derived peptide sequences capable of stimulating T-cells. 
Type Of Material Technology assay or reagent 
Year Produced 2017 
Provided To Others? No  
Impact Peptide-SLA tetramers were constructed and used to track influenza-specific T-cells ex vivo in blood, the lungs and draining lymph nodes. Aerosol immunization with attenuated single cycle influenza viruses (S-FLU) induced large numbers of CD8+ T-cells specific for conserved NP peptides in the respiratory tract. Collectively, these data substantially increase the utility of pigs as an effective model for studying protective local cellular immunity against respiratory pathogens. 
 
Title NGS for PPR virus whole genome sequencing 
Description We have finalised a protocol to sequence the whole genome of PPR virus 
Type Of Material Technology assay or reagent 
Year Produced 2017 
Provided To Others? Yes  
Impact The method has been described and shard with project partners and a draft has been written for publishing the methods 
 
Title method for identification of lung Tissue resident memory cells in pigs 
Description Recent overwhelming evidence indicates the importance of local tissue-resident memory T cells (TRM) in protective immunity. Most work on TRM has been performed in mice and the TRM defined as inaccessible to intravenously administered anti-T cell antibody. However there are very few data on TRM in large animals. For the first time we have defined TRM in the pig influenza model. 
Type Of Material Technology assay or reagent 
Year Produced 2018 
Provided To Others? No  
Impact The identification of TRM and their robust protective capacity in site-specific infection has provided a new paradigm by which to assess T cell-mediated responses and an important new target for vaccine design. Since swine are an economically important species, are used as a large animal model for human infection and play a key role in the emergence of novel and potentially zoonotic influenza viruses, the identification of TRM in pigs will allow us to study their role in immunity to swine influenza.and how best to induce them by immunisation. 
 
Description Aerosol delivery of vaccines and therapeutics 
Organisation Aerogen
Country Ireland 
Sector Private 
PI Contribution Developed the pig influenza model which is a natural host pathogen system
Collaborator Contribution Provided expertise and equipment for aerosol delivery
Impact Successfully delivered vaccines by aerosol
Start Year 2015
 
Description Anihwa Call 1 
Organisation Agricultural Research for Development (CIRAD)
Country France 
Sector Public 
PI Contribution Developed PCR to detect PPR viral genome in faecal samples for experimentally infected animals.
Collaborator Contribution Developed PCR and antigen ELISA to detect PPR viral genome in faecal samples for field animals including wild life.
Impact Please see publications
Start Year 2013
 
Description Anihwa Call 1 
Organisation Friedrich Loeffler Institute
Country Germany 
Sector Public 
PI Contribution 1. Conducted challenge experiments in goats to study pathogenicity. 2. Developed NGS technology to sequence PPR whole genome.
Collaborator Contribution FLI has conducted transmission study between different species ( Goats, pig, camel). For the first time they showed that pigs are clinically infected by PPR virus.
Impact Joint Publications
Start Year 2013
 
Description Anihwa Call 1 
Organisation International Atomic Energy Agency
Country Austria 
Sector Public 
PI Contribution 1. Phylogenetic analysis and whole genome sequencing
Collaborator Contribution 1.Phylogenetic analysis and whole genome sequencing
Impact Joint publications
Start Year 2013
 
Description Anihwa Call 1 
Organisation Kimron Veterinary Institute
PI Contribution 1.Analysed evolution of PPR viruses from 1993 to 2017 circulating in Israel by conducting whole genome sequencing and Bayesian analysis .
Collaborator Contribution Submitted virus to Pirbright
Impact Joint publications
Start Year 2013
 
Description Assembly of CHIKV in host cells/JEOL TEM training 
Organisation National Cheng Kung University
Country Taiwan, Province of China 
Sector Academic/University 
PI Contribution Visit to Tainan in May 2017, provided training in cellular imaging of virally infected cells. Gave a seminar entitled Bioimaging at The Pirbright Institute. Hosted two visitors for two weeks in Bioimaging at Pirbright, provided training in EM sample preparation and data interpretation.
Collaborator Contribution Professor Shang-Rung Wu hosted me for one week in Taiwan. During the visit to Pirbright, the Taiwanese researchers provided training on JEOL 2100F TEM to Pirbright researchers. Professor Wu provided prepared samples for imaging at a later date.
Impact No outputs yet
Start Year 2017
 
Description Assembly of DNA virus (tegumentation of HSV) 
Organisation University of Surrey
Country United Kingdom 
Sector Academic/University 
PI Contribution Use of advanced microscopes to investigate tegumentation of HSV
Collaborator Contribution Molecular biology skills and reagents for investigating tegumentation of HSV
Impact Joint Pirbright-Surrey PhD studentship
Start Year 2018
 
Description BBSRC-UC Davis workshop, 16-18 October 
Organisation University of California, Davis
Department UC Davis College of Biological Sciences
Country United States 
Sector Academic/University 
PI Contribution Presented on "Reproducibility and relevance in vector infection studies". Followed up with discussion of potential publication and funding opportunities.
Collaborator Contribution Various presentations on vectors and vector-borne diseases including, facilities, challenges, opportunities.
Impact Discussion of potential joint publications and grant applications; no tangible impacts yet.
Start Year 2017
 
Description BBSRC-UC Davis workshop, 16-18 October 
Organisation University of Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution Presented on "Reproducibility and relevance in vector infection studies". Followed up with discussion of potential publication and funding opportunities.
Collaborator Contribution Various presentations on vectors and vector-borne diseases including, facilities, challenges, opportunities.
Impact Discussion of potential joint publications and grant applications; no tangible impacts yet.
Start Year 2017
 
Description Collaboration on replication of mumps virus in cells 
Organisation University of Copenhagen
Country Denmark 
Sector Academic/University 
PI Contribution Intellectual input so far, training research assistant to prepare samples, imaging samples in transmission electron microscopes
Collaborator Contribution Preliminary confocal microscopy to optimize sample conditions. Preparation of samples for EM.
Impact No outcomes yet
Start Year 2018
 
Description Collaboration with Bauchi State Veterinary Services, Nigeria 
Organisation Bauchi State University
PI Contribution We have provided expertise on sheeppox, goatpox and lumpy skin disease virus diagnosis and epidemiology
Collaborator Contribution Our collaborators in Bauchi State have provided virus samples and epidemiological data
Impact Preliminary data was used to support successful funding via a BBSRC Impact Accelerator Award, and a Pathways to Impact project in BBSRC project BB/R008833/1 "Development of rationally designed live-attenuated lumpy skin disease vaccines"
Start Year 2016
 
Description Collaboration with State Central Veterinary Laboratory, Mongolia 
Organisation State Central Veterinary Laboratory
PI Contribution We provided tools, techniques and expertise on sheeppox and goatpox
Collaborator Contribution Our colleagues provided data and field samples
Impact A workshop was held in Pirbright in March 2017, and a return workshop in Ulaanbaatar in July 2017. Preliminary data supported successful grant applications for an Impact Accelerator Award, and a Pathways to Impact project in BB/R008833/1 "Development of rationally designed live-attenuated lumpy skin disease vaccines".
Start Year 2016
 
Description Collaboration with University of Copenhagen CFIM on cell biology of virus-host interactions 
Organisation University of Copenhagen
Country Denmark 
Sector Academic/University 
PI Contribution Intellectual input into virus projects which come in to the microscopy core facility at the University. Limited practical work and training given to researchers there.
Collaborator Contribution Research projects are presented to the core facility, I advise on the best route for achieving the data required and those researchers complete preliminary data following my advice. Collaborators are then able to produce the best possible samples for further advanced microscopy as necessary.
Impact No tangible outcomes yet as we are in early stages. This is multi-disciplinary as projects can come from several University departments (medical, pathology, cell biology, veterinary, food), and other Universities in Denmark (DTU).
Start Year 2018
 
Description Collaborative studentship PPRV 
Organisation University of Surrey
Department School of Veterinary Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Practical laboratory work and in vivo animal studies carried out
Collaborator Contribution Intellectual input in scientific remit of studentship, training of student, use of facilities and lab
Impact DOI: 10.1128/JVI.01471-18 Thesis: The immune response to live, attenuated peste des petits ruminants virus vaccines
Start Year 2014
 
Description DTU 
Organisation Technical University of Denmark
Country Denmark 
Sector Academic/University 
PI Contribution Joint PhD studentship
Collaborator Contribution Joint PhD studentship
Impact Joint PhD studentship in progress
Start Year 2016
 
Description Development of tetramers in the Babraham pig model 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Developed the aerosol delivery method of vaccine and provided material (spleen, BAL and blood) from inbred animals (Babraham pigs) following immunisation with the candidate universal vaccine, S-FLU.
Collaborator Contribution Developed porcine influenza specific class I tetramers and provided the epitope map of Babrahams S-Flu responses to NP, M1, M2, PB1 and PB2 that could be presented by SLA-1 or SLA-2 Grew pig T cell clones for the first time in 30 years.
Impact Multidisciplinary - immunology, virology, protein chemistry. Paper not yet published
Start Year 2014
 
Description Dundee 
Organisation University of Dundee
Country United Kingdom 
Sector Academic/University 
PI Contribution Co-INvestigator on BBSRC sLoLa award
Collaborator Contribution Co-INvestigator on BBSRC sLoLa award
Impact BBSRC sLoLa award ongoing
Start Year 2012
 
Description Edinburgh 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Co-INvestigator on BBSRC sLoLa award
Collaborator Contribution Co-INvestigator on BBSRC sLoLa award
Impact BBSRC sLoLa award ongoing
Start Year 2012
 
Description Efficacy of a candidate universal influenza vaccine, S-FLU. 
Organisation University of Oxford
Department Radcliffe Department of Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Tested the immunogenicity and efficacy of a candidate universal influenza vaccine, S-FLU, in pigs. For the first time we demonstrated that S-FLU when administered by aerosol can reduce viral load in nasal swabs and lung in pigs after influenza virus challenge. We have shown that the most efficient way to administer this vaccine is by aerosol.
Collaborator Contribution Professor Alain Townsend has developed the S-FLU vaccine.
Impact The most efficient way to induce immune response in the lung is after aerosol delivery of LAIV vaccines in pigs. The most efficient way to induce cross-protective immunity is by aerosol delivery of S-FLU to the lungs of pigs
Start Year 2014
 
Description Genetic analysis orbiviruses 
Organisation University of Surrey
Department Faculty of Health and Medical Sciences
Country United Kingdom 
Sector Academic/University 
PI Contribution Virus sequences provided for analysis. Meeting and discussion for analysis by virologist employed on this project and biomathematican at the University of Surrey
Collaborator Contribution Analysis of data, training of the virologist and computational and mathematical methodology, discussion about analysis strategies
Impact The collaboration is multi-disciplinary - between mathematical modelling and virology. Data analysis is still ongoing but is envisaged as preliminary data for future funding applications
Start Year 2017
 
Description High containment microscopy with Thermo Fisher 
Organisation Thermo Fisher Scientific
Country United States 
Sector Private 
PI Contribution Provide advice on decontamination protocols
Collaborator Contribution Development/optimisation of microscope decontamination procedures
Impact No outputs yet, very early stages of collaboration
Start Year 2019
 
Description Imperial 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Joint supervision of PhD student
Collaborator Contribution Joint supervision of PhD student
Impact One successful completed PhD student. Papers published or in preparation. Another PhD student in progress.
Start Year 2010
 
Description Interferon stimulated genes 
Organisation Royal Veterinary College (RVC)
Country United Kingdom 
Sector Academic/University 
PI Contribution Hosted meetings and carried out preliminary experiments
Collaborator Contribution Contributed reagents and expertise
Impact Preliminary data was used to support an MSc project. This has since led to a publication and a PhD project.
Start Year 2016
 
Description Investigating antigenic determinants inducing stronger and broader cross-protective immunity among H5 avian influenza viruses 
Organisation Royal Veterinary College (RVC)
Department Veterinary Basic Sciences
Country United Kingdom 
Sector Academic/University 
PI Contribution The overarching aims of the proposed research are to improve controls against H5 subtype of avian influenza viruses infecting poultry by investigating underlying mechanisms that define how vaccines renders effectiveness and develop novel approaches enhancing the effectiveness of H5 avian influenza vaccines. We recently generated a panel of monoclonal antibodies (mAbs) that recognise a variety of different clades of H5 viruses. Propagation of AIV in eggs or cultured cells together with mAbs drives virus to escape from mAbs neutralisation activity. These classical virus neutralization assays (VN) followed by HA gene sequence analysis allowed us to defined the role of amino acid substitutions that are associated with evasion of antibody neutralization through emergence of antigenic variants and failure of vaccine efficacy.
Collaborator Contribution provided intellectual input for achieving prescribed objectives of this work.
Impact Talk entitled "Molecular determinants for antigenicity and vaccine efficacy of avian influenza viruses" was presented at Newton Agham Researcher Links Workshop " Novel Vaccines and Diagnostic Technologies against Emerging and re-emerging Veterinary Pathogens" at Rizal Park Hotel, Manila, Philippines, 4-7 February 2019.
Start Year 2019
 
Description JN - Preparation of capped mesoporpus silica nanoparticles 
Organisation Polytechnic University of Valencia
Country Spain 
Sector Academic/University 
PI Contribution We were involved with testing the nanoparticles once they had been made. We also contributed purified antibody and shipped it to our collaborators for the generation of one type of nanoparticle, which we subsequently tested. We were involved with the intellectual design of experiments
Collaborator Contribution Our partners generated the nanoparticles and shipped them to us for testing. Our partners were also involved with the intellectual design of experiments.
Impact Experimental work performed to investigate the use of mesoporous silica nanoparticles to detect FMDV proteases in clinical samples
Start Year 2016
 
Description LMB 
Organisation Medical Research Council (MRC)
Department MRC Laboratory of Molecular Biology (LMB)
Country United Kingdom 
Sector Public 
PI Contribution Collaboration
Collaborator Contribution Collaboration
Impact Collaborative research
Start Year 2016
 
Description Leeds FBS 
Organisation University of Leeds
Department Leeds Institute of Molecular Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Research
Collaborator Contribution Research and student supervision
Impact Research
Start Year 2009
 
Description Merial 
Organisation Sanofi
Department Merial Plc
Country Global 
Sector Private 
PI Contribution BBSRC Link award
Collaborator Contribution BBSRC Link award
Impact BBSRC Link award in progress
Start Year 2016
 
Description Mosquito Interest Group 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Organising and attending meetings of students, RAs, postdocs and PIs on mosquito biology and related techniques.
Collaborator Contribution Organising and attending meetings of students, RAs, postdocs and PIs on mosquito biology and related techniques.
Impact Exchange of practical techniques, for instance in tracking oviposition of individual mosquitoes. Brainstorming for projects and papers, resulting in a GCRF VBD network proposal (which passed the first review but was not funded in the second) and an informal collaboration (which was intended for submission to UK-Thai call in 2017 but Thai partner was not eligible). Exchanges of colony strains of insects planned this month.
Start Year 2016
 
Description Mucosally Associated Invariant T cells (MAIT) in pig influenza model 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Identified MAIT cells in pig Influenza model. Provide samples from infected and immunised protected animals
Collaborator Contribution Provide expertise in characterising MAIT: development of tetramer; Zell scanner technology allowing high resolution studies of cell phenotype and functions
Impact Joint PhD studentship with Paul Klenerman, University of Oxford
Start Year 2016
 
Description Novel PRRS and swine influenza vaccines 
Organisation National Center for Genetic Engineering and Biotechnology (BIOTEC)
Country Thailand 
Sector Public 
PI Contribution Expertise in PRRS immunology and vaccine evaluation.
Collaborator Contribution Novel vaccine strains and SE Asian field strains
Impact Collaborative grant proposal funded under the BBSRC Newton Fund UK-China-Philippines-Thailand Swine and Poultry Research Initiative
Start Year 2017
 
Description Oxford - Strubi 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration on virus structural biology and joint PhD studentship
Collaborator Contribution Collaboration on virus structural biology and joint PhD studentship
Impact Collaboration on virus structural biology has produced a number of novel virus structures and new understanding of virus entry and packaging
Start Year 2008
 
Description PRRS and Influenza co-nfection studies 
Organisation Government of Thailand
Department National Science and Technology Development Agency (NSTDA)
Country Thailand 
Sector Public 
PI Contribution The Pirbright team of 4 scientists with expertise in immunology and animal care visited Thailand in July 2018 to train Thai colleagues to perform animal experiments (Chiang Mai) and analyse immune responses by ELISPOT and Flow cytometry (Bangkok). This provided Thailand with trained personnel and expertise in testing vaccines in pigs. As a result of the joint work, the Chiang Mai animal facility is currently being renovated. Development of such an animal facility will promote the production and testing of more vaccines by Thai scientists.
Collaborator Contribution Our Thai colleagues provided us with local Thai PRRS and Influenza virus strains which we use in our co-infection studies.
Impact None yet
Start Year 2018
 
Description Pathology of BTV in T cell depleted sheep 
Organisation University of Surrey
Department School of Veterinary Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Carrying out animal studies, taking samples for histopathology and sending material
Collaborator Contribution Certified pathologist will attend selected necropsies, sample processing and pathological analysis
Impact Protocols and sample sending established - first clinical trial to start in March 2018
Start Year 2017
 
Description Pathology of bovine skin post Culicoides midge blood-feeding 
Organisation University of Surrey
Department School of Veterinary Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Collection of skin samples from cattle responding with local inflammation to Culicoides biting midges blood feeding, sending of materials
Collaborator Contribution Processing of samples, histopathological analysis, sharing of results
Impact Further identification of cellular and histological local changes in ruminant skin to Culicoides blood-feeing which will inform pathogenesis of co-transmitted arboviruses such as BTV
Start Year 2017
 
Description Paul Verkade - Electron tomography and CLEM 
Organisation University of Bristol
Department Avon Longitudinal Study of Parents and Children (ALSPAC)
Country United Kingdom 
Sector Academic/University 
PI Contribution Nicole Doyle has performed electron tomography to analyse the three dimensional structure of membrane rearrangements induced by the expression of IBV non-structural proteins 4 or 3 and 4 in the absence of other viral components. Sample set up was performed at Pirbright and analysis was subsequently performed at University of Bristol followed by additional analysis at Pirbright.
Collaborator Contribution Paul has assisted with electron tomography data generation providing access to electron microscopes in Bristol as well as training for Nicole Doyle in performing experiments and analysing and modelling data. He is also advising Nicole while establishing correlative light electron microscopy at Pirbright.
Impact doi: 10.3390/v10090477
Start Year 2018
 
Description Professor Sahyan Sharif, University of Guelph, Canada 
Organisation University of Guelph
Department Department of Pathobiology
Country Canada 
Sector Academic/University 
PI Contribution Collaboration between my team and Professor Sharif lead to new finding in Avian immunology, specifically in understanding the effects of nutrients on antigen presenting cells and T cells of chicken. We took the lead in studying the effects of some nutrients (Vitamin D) on the function of chicken T cells, performed most of the experiments in our laboratory. Meanwhile, we participated in studying the effects of Vitamin D on antigen presenting cells of chicken by performing some key experiments because we had access to some specific reagents (monoclonal antibodies) recognizing molecules expressed on chicken antigen presenting cells.
Collaborator Contribution Professor Sharif team took the lead in studying the effects of Vitamin D on antigen presenting cells of chicken, and contributed to experimental plan for studying the effects on chicken T cells.
Impact Two publications in 2015 and 2016: 1. Nitish Boodhoo, Shayan Sharif, Shahriar Behboudi. 1a,25(OH)2 Vitamin D3 Modulates Avian T Lymphocyte Functions without Inducing CTL Unresponsiveness. PLoS One. 2016 Feb 24;11(2):e0150134 2. Bahram Shojadoost, Shahriar Behboudi, Villanueva AI, Jennifer Brisbin, Ali Ashkar, Shayan Sharif. Vitamin D3 modulates the function of chicken macrophages. Res. Vet. Sci. 2015 June, 100: 45-51
Start Year 2014
 
Description Provision of PRRSV field strains 
Organisation Animal and Plant Health Agency
Country United Kingdom 
Sector Public 
PI Contribution Experimental heterologous PRRSV challenge model to assess the induction of broadly neutralizing antibodies. Model to assess dendritic cell tropism of PRRS viruses
Collaborator Contribution Provision of PRRSV-1 and -2 field strains
Impact Not yet
Start Year 2016
 
Description Provision of PRRSV field strains 
Organisation Kansas State University
Country United States 
Sector Academic/University 
PI Contribution Experimental heterologous PRRSV challenge model to assess the induction of broadly neutralizing antibodies. Model to assess dendritic cell tropism of PRRS viruses
Collaborator Contribution Provision of PRRSV-1 and -2 field strains
Impact Not yet
Start Year 2016
 
Description Reporter PRRS viruses 
Organisation Kansas State University
Country United States 
Sector Academic/University 
PI Contribution A new application for recombinant reporter PRRS viruses i.e. to use them as a high throughput screen for neutralizing (monoclonal) antibodies. Use as tools to assess the tropism of PRRSV for dendritic cell subsets and the functional consequences.
Collaborator Contribution Provision of plasmids encoding GFP-expressing PRRSV-1 and -2.
Impact Not yet
Start Year 2016
 
Description Retroviral-mediated genetic programming of porcine memory B cells 
Organisation AIMM Therapeutics
PI Contribution Provided a novel 'model' system to test their technology to isolate novel monoclonal antibodies
Collaborator Contribution To provide their patented platform technology to genetically program porcine memory B cells to enable the isolation of memory B cells
Impact Not yet
Start Year 2016
 
Description Semiochemical-based detection of arboviral infection 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Preliminary data collection on the influence of arboviral infection on semiochemical output from sheep. These studies are being conducted as part of an unrelated animal experiment within the isolation units at Pirbright. We are carrying out the animal-based studies and collecting air entrainments from animals both pre- and post-infection. These are then decontaminated for movement to LSHTM.
Collaborator Contribution LSHTM are carrying out analysis of air entrainments using GC-MS. They will assess differences in profiles of infected vs uninfected animals and report their findings to us.
Impact Still ongoing.
Start Year 2018
 
Description SiSaf Ltd, FMDV + carriers 
Organisation SiSaf Ltd
PI Contribution Advice on experimental design, provision of FMDV empty capsids (Alison Burman). Will do practical work in the future.
Collaborator Contribution Preparation of carrier formulations
Impact No outputs yet
Start Year 2019
 
Description St Andrews 
Organisation University of St Andrews
Country United Kingdom 
Sector Academic/University 
PI Contribution Co-investigator on BBSRC sLoLa
Collaborator Contribution Lead-investigator on BBSRC sLoLa
Impact BBSRC sLoLa ongoing
Start Year 2012
 
Description Swine haplotyping 
Organisation Gift Of Life
PI Contribution Prepared and shipped samples
Collaborator Contribution Sample analysis
Impact Data generation. Not multi-disciplinary
Start Year 2016
 
Description The GCRF One Health Poultry Hub 
Organisation Royal Veterinary College (RVC)
Country United Kingdom 
Sector Academic/University 
PI Contribution The focus of the research is to achieve sustainable global intensification of poultry meat and egg production whilst reducing risks to human and animal health and welfare. We are undertaking research to investigate the diversity of avian influenza viruses prevalent in poultry and wild birds in south east Asia.
Collaborator Contribution Royal Veterinary College, London is leading this GCRF One Health Poultry Hub. The project will address the need to meet rising demand for poultry meat and eggs in developing countries, while minimising risk to international public health. Population growth is driving global demand for poultry, meat and egg production; this unfortunately creates conditions in which animal diseases can spread to humans ('zoonoses'). These include bacterial food poisoning and strains with avian influenza with epidemic or pandemic potential. The GCRF One Health Poultry Hub will adopt a 'One Health' approach to the issue of combatting animal-to-human diseases by bringing together a team of laboratory, clinical, veterinary and social scientists. This team will test and evaluate novel interventions. The need for safe poultry production is most urgent in South and South East Asia, so the RVC and its partners will then use their local networks in these regions to put its positive research to immediate use.
Impact Development of international interdisciplinary partnership of 55 investigators from 13 countries to address the emerging global challenges of food security and public health associated with intensification of poultry production.
Start Year 2018
 
Description The effect of the microbiota on immunity to swine infleunza 
Organisation University of Surrey
Country United Kingdom 
Sector Academic/University 
PI Contribution We wish to establish the gut and nasal microbiome in normal healthy pigs and how this is affected by influenza infection. We have collected gut samples from pigs at different stages of infection, as well as nasal swabs which we will provide to our collaborators in Surrey.
Collaborator Contribution Our collaborators in Surrey will perform the sequencing and bioinformatics analysis to determine the microbial communities present in the samples.
Impact No outcomes yet - we are in the process of analysing the samples.
Start Year 2017
 
Description Thomas Bowden - STRUBI - University of Oxford - Glycoprotein structure collaboration 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of data and advice about the biological properties of viral glycoproteins, e.g. their fusion capacity with various receptors, their role in determining host-range
Collaborator Contribution Advice and technical support at the structural level supporting future project development and design
Impact No outcomes as yet
Start Year 2018
 
Description Use of fluorescent virions to isolate PRRSV-specific porcine B cells 
Organisation University of Minnesota
Country United States 
Sector Academic/University 
PI Contribution Deployment of a novel technology to facilitate isolation of PRRSV neutralizing monoclonal antibodies
Collaborator Contribution Provision of a method to fluorescently tag purified virions to label PRRSV-specific B cells
Impact None to report to date
Start Year 2016
 
Description York 
Organisation University of York
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration
Collaborator Contribution Collaboration
Impact Collaboration
Start Year 2015
 
Description Talk Presented at 2nd International Congress of Veterinary Microbiology, 16th -19th October 2018. Sherwood Breezes Resort-Lara, Antalya, Turkey. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Conference discussed improving prevention and control of viral diseases of poultry.
Year(s) Of Engagement Activity 2018
 
Description "Challenges for Poultry Industry". Organised by Fakieh Poultry at the Ritz-Carlton Hotel in Jeddah, Saudi Arabia, 2nd -3rd December 2018, 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Conference discussed prevention and control of infectious diseases affecting poultry production.
Year(s) Of Engagement Activity 2018
 
Description "Interactive session with poultry stakeholders". Title: Overview of Avian Influenza group Research at The Pirbright Institute. Presented at University of Veterinary and Animal Sciences (UVAS) Lahore, Pakistan, 3rd August 2018. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The workshop discussed the economic impacts and prevention strategies against avian influenza viruses affecting poultry production and zoonotic infections.
Year(s) Of Engagement Activity 2018
 
Description 2. Overview of Avian Influenza group Research at The Pirbright Institute. Presented at "Interactive session with poultry stakeholders" at University of Veterinary and Animal Sciences (UVAS) Lahore, Pakistan, 3rd August 2018. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dissemination of research Project outcomes These include presenting research data for vaccine seed strains with emergent field avian influenza variants; The zoonotic risk posed by emerging avian influenza viruses circulating in the wild birds and poultry. Impact of virus evolution on vaccine efficacy and persistence in poultry.
Year(s) Of Engagement Activity 2018
 
Description 360 degree Lab Animal Tour (and film) of The Plowright Building, The Philip Mellor Insectary, and Animal Isolation Facilities 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The website provides unique access to the animal research facilities at The Pirbright Institute which support its world-leading scientific research into livestock viral diseases and helps save countless animal and potentially human lives, globally. Produced and filmed by Understanding Animal Research, the Lab Animal Tour was filmed at Pirbright, and at three other research centres, and provides the viewer with an interactive 360 virtual tour of the animal facilities.
Year(s) Of Engagement Activity 2017
URL http://www.labanimaltour.org/pirbright
 
Description Animal Technician talk at Woking College 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact External talk at Woking Sixth Form College
Year(s) Of Engagement Activity 2017
 
Description Ash Manor GCSE Mentoring 2018 - BA 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Stimulating increased interest in research
Year(s) Of Engagement Activity 2018
 
Description BBC World Service Science Programme "Science in Action" Broadcast 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact This was an broadcast with BBC World Service Science in Action Programme to inform the public about the current African swine fever situation and provide information on pathogenesis mechanisms of transmission and our research on vaccine development
Year(s) Of Engagement Activity 2018
URL http://www.bbc.co.uk/programmes/p002vsn
 
Description Bluetongue and Wildlife (15 minute presentation on Epizootic Haemorhagic Disease Virus), (July/Pirbright, UK) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Policymakers reported greater interest in deer-associated diseases including EHDV and BTV
Year(s) Of Engagement Activity 2018
 
Description Broadcast on African swine fever on BBC wolrd service "The Food Chain" 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Interview with BBC World Service "The Food Chain" on African swine fever virus.
Year(s) Of Engagement Activity 2018
URL https://www.bbc.co.uk/programmes/p05xhflj
 
Description CABI_Research activity of Avian Immunology Group at The Pirbright Institute 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Release of research activity within Avian Immunology group at The Pirbright Institute
Year(s) Of Engagement Activity 2018
 
Description Cafe Scientifique, Bradfield School, West Berkshire: "How insects spread viruses" 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Cafe Scientifique is a public forum for exploring the latest ideas in science and technology. Meetings take place in cafes, bars, restaurants and even theatres, but always outside a traditional academic context. I presented to an audience of the general public and answered questions.
Year(s) Of Engagement Activity 2017
 
Description Cafe Scientifique, Reading: "How insects spread viruses" 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Cafe Scientifique is a public forum for exploring the latest ideas in science and technology. Meetings take place in cafes, bars, restaurants and even theatres, but always outside a traditional academic context. I presented to an audience of the general public and answered questions.
Year(s) Of Engagement Activity 2007,2017
 
Description Cheltenham Science Festival 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Panel discussion at the Cheltenham Science Festival in 2018
One of the biggest threats to our food security is disease of our livestock and crops. Disease affects our economy and the availability of food in our shops. Don King, Head of the World Reference Lab for Foot-and-Mouth Disease, chemical ecologist John Pickett and food systems researcher John Ingram join climate scientist Tamsin Edwards to explore the risks to the UK's food supply and how preventing and controlling these diseases keeps our store cupboards well-stocked.
Year(s) Of Engagement Activity 2018
URL https://www.cheltenhamfestivals.com/science/whats-on/2018/how-safe-is-our-food-supply/
 
Description Cheltenham Science Festival 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Institute stand at the festival covering the Institute science in general, and transmission and gene editing to control disease, in particular.
Year(s) Of Engagement Activity 2018
 
Description Cheltenham Science Festival 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Attended the Cheltenham Science Festival and presented "Pandemic Live" an interactive debate on the spread of viruses in livestock. The audience were guided through the decision making processes that accompany an outbreak of an exotic livestock disease outbreak.
Year(s) Of Engagement Activity 2018
 
Description Conference session organiser at MMC2017 - Host Pathogen Interactions 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Chair for the Imaging Host-Pathogen Interactions session run at MMC2017 (and in previous years). Session usually attracts approx. 30 delegates from national/international backgrounds, mostly academic. Talks sparked discussions and networking opportunities.
Year(s) Of Engagement Activity 2012,2014,2015,2017
 
Description Coronavirus lecture MSc students (Surrey) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact A lecture was presented on the replication, cellular interactions and pathogenesis of coronaviruses to 15-20 MSc students from University of Surrey. The students were engaged and interested, answering and asking questions during the session.
Year(s) Of Engagement Activity 2016,2018
 
Description Development programme public consultation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Public consultation on the Pirbright development programme hosted at the Pirbright Village Hall.
Year(s) Of Engagement Activity 2017
 
Description Diamond open day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Over 300 people visited our stand at the open day, in which we described the importance of our work for food security and public health. Children from all ages were involved and learned about viruses and played with the huge virus particle that we had produced. One of the major impact was that we described to several people why we work on some viruses that we do not have them in the UK, and the importance of the work for the UK and UK economy and public health was explained.
Year(s) Of Engagement Activity 2017
URL http://www.diamond.ac.uk/Public/VisitUs.html
 
Description Encouraging women into science and engineering STEM. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact MH Visited Warwick School, Redhill to talk to secondary students about careers in STEM. A very positive outcome and well received.
Year(s) Of Engagement Activity 2018
 
Description European Society Vector Ecology (Invited Chair for two sessions and speaker for 15min talk); (October/Palermo, Sicily) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Chaired two sessions, one on vector-borne diseases, one on scientific networks. Latter included a discussion with early career researchers. Main outcome was coordination between active networks including The Gnatwork.
Year(s) Of Engagement Activity 2018
URL http://www.sove.org/European%20SOVE%20folder/greecescientificprogram/palermo_Scientific_program_revi...
 
Description Evolution of H9N2 avian influenza virus under immune pressure. Presented at 10th International Symposium on Avian Influenza, 15th - 18th April 2018, The Grand Hotel, Brighton, UK. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The primary aim of the workshop was to forge long-term research partnerships between early-career researchers, livestock industry and national disease control authorities in the UK and the Philippines. In addition, the activity hopes provide information about the emerging and next generation diagnostic and vaccine strategies and their utilization to reduce the impact of viral diseases on livestock and poultry.
Year(s) Of Engagement Activity 2019
URL https://www.slideshare.net/zerep_cire/2019-newton-agham-researcher-links-workshop-vaccines-and-diagn...
 
Description FLI - presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Presentation of current research to the FLI - Germany to build collaborations 19/20 November 2018
Year(s) Of Engagement Activity 2018
 
Description Facebook Live: Infectious Disease Portrayals in Pop Culture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Infectious diseases are a frequent topic in movies. The CDC has used zombies to talk about infectious disease and disaster preparedness, and infotainment has flamed fears of Ebola. I took part in a Facebook Live chat organised by the AAAS Public Engagement team about why infectious diseases are so often the topic of pop culture discussions; what movies, books, and other pop culture gets right and wrong about infectious disease; and how scientists can use pop culture as a jumping-off point for public engagement. The chat was broadcast live on the AAAS Facebook page.
Year(s) Of Engagement Activity 2017
URL https://www.aaas.org/event/facebook-live-infectious-disease-portrayals-pop-culture
 
Description Farnborough futures careers event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact The careers event aimed to introduce the range of careers available at Pirbright. In addition I discussed my own career progression and highlighted the range of possible careers that I could have entered. Finally, I discussed some details of the research with interested students. The students had a wide range of backgrounds and career aims but were interested to hear about the Institute and the sort of work opportunities available. Several of them planned to follow up by investigating future job opportunities at Pirbright.
Year(s) Of Engagement Activity 2019
 
Description Food security and the control of infectious disease in livestock 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A workshop was organized by myself at St Catherine's College Oxford for the duration of three days. Representative from industry, funding agencies and media (publishers) attended this workshop. Over 20 delegates from Egypt and 20 delegates from the UK attended this meeting. The purpose of this workshop/ meeting was to promote international collaborations, provide training for undergraduate students, promote the importance of managing and controlling infectious disease in livestock and public health.
Year(s) Of Engagement Activity 2016
 
Description Fox Corner Community Wildlife Committee 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Pirbright Institute representative on the Fox Corner Community Wildlife Committee - locally held meetings, every 2 months.
Year(s) Of Engagement Activity 2017
 
Description Guest lecturer MSc Imaging course at University of Copenhagen 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact 25 internal students from University of Copenhagen visited the core imaging facility for three days during which time I delivered lectures and interacted with the students during practical workshops. This sparked questions and discussion relating to their individual projects.
Year(s) Of Engagement Activity 2018
 
Description H9N2 avian influenza viruses: impact of evolutionary changes on virus antigenicity, receptor binding and zoonotic potential. Presented at "Conference on Animal Infectious Diseases and Human Health" held at The Veterinary Biotechnology Branch of Chinese Association of Animal Science and Veterinary Medicine & the Veterinary Immunology Branch of Chinese Society for Immunology. August 7th-10th, 2018 Harbin, China. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dissemination of research outcomes to prevent and control of infectious diseases of animals and humans.
- Avian influenza virus evolution and efficacy.
-
Year(s) Of Engagement Activity 2018
 
Description H9N2 avian influenza viruses: impact of evolutionary changes on virus antigenicity, receptor binding and zoonotic potential. Presented at "Conference on Animal Infectious Diseases and Human Health" held at The Veterinary Biotechnology Branch of Chinese Association of Animal Science and Veterinary Medicine & the Veterinary Immunology Branch of Chinese Society for Immunology. August 7th-10th, 2018 Harbin, China. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Focus of the conference was to improve control against infectious diseases affecting poultry and livestock.
Year(s) Of Engagement Activity 2018
 
Description Holt School Surrey. Bee meadow & A-level outreach Talk. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact I discussed the importance of pollinators for biodiversity and food security with the younger students. I also discussed careers in science with A-Level students. There was good interaction and many questions surrounding both topics.
Year(s) Of Engagement Activity 2018
 
Description Immuno-pathobiology of H9N2 avian influenza viruses: looking at how the viruses evolve and persist in poultry. Presented at "Techniques for Healthy Farming and Diseases Prevention & Control of Livestock and Poultry. Beijing, August 13th-15th, 2018. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Dissemination of research outputs. Improvement of vaccines and diagnostics.
Year(s) Of Engagement Activity 2018
 
Description Influenza update 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Approx. 70 scientists attended a Influenza update meeting at which our group presented an oral presentation and poster presentation on our work. These actions resulted in establishment of new collaborations for ongoing work and the initiation of a joint grant writing exercise.
Year(s) Of Engagement Activity 2018
 
Description Influenza update meeting (Pengxiang Chang) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact presented work entitled: Antigenic characterization of avian influenza H7N9 virus by in vitro immune escape mutant selection method.
Year(s) Of Engagement Activity 2018
 
Description InnovSur : Conference in IRD Montpellier on Insect Vector Surveillance 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Working group on standardisation of techniques for surveillance of insect vectors. Included break out group brainstorming and subsequent commentaries. Total audience approximately 110 people for main lectures.
Year(s) Of Engagement Activity 2018
URL https://www.alphavisa.com/isessah-innovsur/2018/
 
Description Innovate Guildford 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Institute stand at the Innovate Guildford event, covering the work of the Institute in general and genetic modification through gene editing specifically.
Year(s) Of Engagement Activity 2018
URL https://www.guildford.gov.uk/IG18
 
Description Innovate Guildford, ND 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Presented at the Pirbright Institute stand discussing science performed by the Institute with the general public. The stand focussed on an exhibit on avian influenza virus but more general virology topics were also discussed including our research.
Year(s) Of Engagement Activity 2017
 
Description Inreview with Daily Telegraph about African swine fever 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Interview with reporter from Daily Telegraph about African swine fever virus and risks to UK farmers
Year(s) Of Engagement Activity 2018
URL https://www.telegraph.co.uk/news/2018/12/12/uk-farmers-warned-alert-african-swine-fever-virus-hits-e...
 
Description Insect Festival 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Ran a stand on blood-sucking arthropods and their role in the transmission of disease at the Royal Entomological Society's Insect Festival. Talked to public, answered questions. Lots of enquiries about ticks, midges, mosquitoes and large biting flies (particularly horseflies).
Year(s) Of Engagement Activity 2017
URL https://www.yorkmuseumstrust.org.uk/whats-on/events/insect-festival-2017/
 
Description Institute stand at Surrey Vet School open day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact Discussion with pupils interested in veterinary medicine (and their parents) about the Institute, its role and livestock disease in general.
Year(s) Of Engagement Activity 2013,2015,2016
 
Description International Avian Respiratory Disease Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Michael presented his research at the 2018 International Avian Respiratory Disease Conference in the US to an audience of avian researchers and representatives form the poultry veterinary vaccine industry. This sparked discussion and potential future collaborations
Year(s) Of Engagement Activity 2018
 
Description International Congress of Entomology (Florida) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Chaired session and gave presentation on progress in Culicoides research. Largest ever meeting involving the Culicoides community with 100+ attendees.
Year(s) Of Engagement Activity 2016
URL http://ice2016orlando.org/
 
Description International Day of Women and Girls in Science 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact I gave a quote as a STEM ambassador about why I think it is important to make sure women and girls have the same opportunities in STEM. This was shared on social media to celebrate International Day of Women and Girls in Science, a UN-led initiative.
Year(s) Of Engagement Activity 2019
 
Description Interview with BBC Radio 4 Inside Science 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact An interview with BBC Radio 4 Inside Science producers to inform them about African swine fever virus and our research on vaccine development
Year(s) Of Engagement Activity 2018
URL http://www.bbc.co.uk/programmes/p05v91jq
 
Description Interview with CNN on African swine fever virus 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Interview with Nina Avramova from CNN International about African swine fever virus generally including transmission mechanisms and control strategies
Year(s) Of Engagement Activity 2018
URL https://edition.cnn.com/2018/10/02/health/african-swine-fever-europe-china-spread-intl/index.html
 
Description Interview with Health for Animals about African swine fever vrius vaccine development and current situation 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Interview with journalists from Health for Animals about African swine fever vaccine research published in a newsletter sent to 200 people.
Year(s) Of Engagement Activity 2018
URL https://healthforanimals.org/resources-and-events/newsletter-repository/17-disease-outbreaks.html?q=...
 
Description Interview with IEG Policay about ASFV vaccines 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Interview with Peter Rixon of IEG policy about the prospects for development of vaccines for African swine fever vrius
Year(s) Of Engagement Activity 2018
URL https://iegvu.agribusinessintelligence.informa.com/CO221819/ASF-outbreak-in-Belgium-highlights-lack-...
 
Description Invited Chair at European Congress of Entomology (Naples,July) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Chaired session on vector-borne diseases at meeting and subsequent question sessions with 15 minute presentation on Culicoides biting midges.
Year(s) Of Engagement Activity 2018
URL http://www.ece2018.com/scientific-programme/day-1-monday-2-july/
 
Description Invited Presentation 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Presentations at the European PRRS Research Award ceremonies
Year(s) Of Engagement Activity 2016,2017
 
Description Invited oral presentation at 18th National Conference for Pig Disease Prevention and Eradication, Wuhan, China 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited oral presentation: 'Trying to hit a moving target: Novel approaches to porcine reproductive and respiratory syndrome virus vaccine development', 18th National Conference for Pig Disease Prevention and Eradication, Wuhan, China
Year(s) Of Engagement Activity 2018
 
Description Invited presentation at the Friedrich Loeffler Institute (January; Riems) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Formal presentation on biting midges and bluetongue to professional audience with question session and collaborative meetings
Year(s) Of Engagement Activity 2019
 
Description Invited presentation: 'Beyond Jenner: The Future of Vaccines', Discovery Day, Dr Jenner House Museum and Gardens 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Invited by the British Society for Immunology to give a presentation on vaccine research at the 'Beyond Jenner: The Future of Vaccines', Discovery Day, Dr Jenner House Museum and Gardens, Berkeley, UK.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker - Moredun 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation on Bioimaging capabilities at Pirbright to Moredun Institute. Attended by Head of Bioimaging at Roslin too, increased links between these institutes.
Year(s) Of Engagement Activity 2016,2018
 
Description Invited speaker - PHE Colindale 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation on high containment microscopy, asking for my advice prior to the design of a new high containment microscopy facility at PHE. This sparked a discussion at the end of the meeting, and several key points of advice that I put forward for them to consider during this process. I made it clear that I am available for other discussions at a later date if needed.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker - RMS EM School 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited to lecture on certain aspects of electron microscopy. I provided advice on individuals difficulties they had with sample preparation. Delegates had the opportunity to ask me any questions then had relating to any sample type.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker British Society of Veterinary Pathology Annual Meeting 2018, Applied Ruminant Pathology 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speaker on "Bluetongue virus and Schmallenberg virus - recognising the continued threat of Culicoides-borne viruses of ruminants" British Society of Veterinary Pathology Annual Meeting 2018, Applied Ruminant Pathology
School of Veterinary Medicine, University of Surrey, 29th of September 2018,
Year(s) Of Engagement Activity 2018
URL https://www.bsvp.org/event/applied-ruminant-pathology-disease-investigation-diagnosis-and-surveillan...
 
Description Invited speaker VECTOR-BORNE DISEASES (VBD) IN THE UK - BIENNIAL MEETING 2018 John Innes Centre Norwich 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speaker on "The Host-vector-pathogen Interface of Culicoides-borne Bluetongue Virus" at the VECTOR-BORNE DISEASES (VBD) IN THE UK - BIENNIAL MEETING 2018 John Innes Centre Norwich 4th-5th December 2018
Year(s) Of Engagement Activity 2018
 
Description Invited speaker at APHA surveillance meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speaker on insect surveillance at Animal and Plant Health Agency meeting with discussion around current studies.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker at Imperial College 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Gave a talk on our recent research in swine influenza. Discussions with PIs at Imperial after the talk. Established collaborations.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker, Merseyside BSI Affinity group 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact I described the methods we used to identifyTissue resident memory cells in pigs, which sparked a lively discussion and interest in the technique. As a result I have established two collaborations with colleagues from Liverpool.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker, Surrey University 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Under- and postgraduate students attended a talk I gave at the Department of Biological Sciences in Surrey. There was a lively discussion afterwards and as a result I have established a new collaboration.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker, Vienna Veterinary School 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Gave a guest lecture at the Veterinary school in Vienna. There were a lot of questions and discussion after the talk. As a result established collaboration with Gerner Wilhelm's group.
Year(s) Of Engagement Activity 2019
URL https://www.vetmeduni.ac.at/de/graduate-school-pig-and-poultry-medicine/
 
Description Invited to attend and present at the RSPCA Lay members Forum, Royal Society London 10th of December 2018 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Third sector organisations
Results and Impact Invited to attend to the RSPCA Lay members Forum, Royal Society London 10th of December 2018 and present on the ethical review process of animal research
Year(s) Of Engagement Activity 2018
URL https://science.rspca.org.uk/sciencegroup/researchanimals/ethicalreview/differentsystems/uk/events
 
Description JN - Woking school 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Careers Fair at a local school encouraging children to consider science as a career and representing the institute in the local community.
Year(s) Of Engagement Activity 2008
 
Description Jennifer Simpson - Big Bang Competition judge 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact The Big Bang Competition recognises and rewards young people's achievements in all areas of science, technology, engineering and maths (STEM), whilst providing them with the opportunity to build their skills and confidence in project-based work. The Competition is open to all UK residents in full-time education or training.
Year(s) Of Engagement Activity 2017,2018
 
Description Jennifer Simpson - Careers Fair at Woking High School 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Pirbright Institute stand at the careers fair. Speak to students interested in a career in science. Sparked questions and discussions.
Year(s) Of Engagement Activity 2018
 
Description Jennifer Simpson - Girls into STEM 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Outreach activity for girls in local schools to demonstrated the variety of careers available within the STEM sector.
Year(s) Of Engagement Activity 2018
 
Description Jennifer Simpson - InFocus article on Bioimaging in high containment 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Magazine article describing the facilities for imaging in high containment at Pirbright.
Year(s) Of Engagement Activity 2018
 
Description Jennifer Simpson - Surrey MSc students visit to Pirbright 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Jenny organized a practical session where the students prepared their own samples for the confocal microscope, then they were able to image these samples using our instrument. The activities provoked questions and discussion. This session is always very warmly received by the students.
Year(s) Of Engagement Activity 2017,2018,2019
 
Description Katy Moffat - Surrey MSc student visit to Pirbright 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Katy ran a small workshop for the students which enabled them to see the whole flow cytometry workflow. These activities provoke questions and discussions, and are always very warmly received.
Year(s) Of Engagement Activity 2017,2018,2019
 
Description Keynote speaker - Danish Virology Society Annual Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact I was personally invited to be keynote speaker at the annual meeting of the Danish Virology Society, to talk about high containment microscopy of cell biology of host-virus interactions. The meeting was held at the State Serum Institute in Copenhagen, followed by a social evening which enabled me to add new contacts into my network. This invitation came direct from the Danish Virology Society, independent of the work I already do with the University of Copenhagen.
Year(s) Of Engagement Activity 2018
 
Description Kingdown School Warminster Wiltshire talk to 6th form students about career in science. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact I presented my career path to the students to engage them on STEM careers. I had a good level of discussion and many questions.
Year(s) Of Engagement Activity 2018
 
Description Laboratory Science Animal association (LASA) meeting in Birmingham, Invited speaker 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Gave a presentation on the tolls we have developed to study swine influenza
Year(s) Of Engagement Activity 2018
URL http://www.lasa.co.uk/meetings/
 
Description Launch of first industry guidance on safe working with arthropods and GM insects 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Around 50 biosafety professionals and regulators including representatives from HSE attended the formal launch of the first industry guidance on working safely with arthropods and genetically modified insects on 21st April at Pirbright. This initiative originated with Sharon Webster, Chair of ISTR's Biosafety Steering Group, and was developed based on consultation with myself and members of my group with practical experience of working with arthropods in containment.
Year(s) Of Engagement Activity 2017
URL https://www.pirbright.ac.uk/news/2017/04/first-industry-guidance-safe-working-arthropods-and-gm-inse...
 
Description Laura Dunn - Female role models 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Careers day for secondary school students, with the focus on careers for women in science
Year(s) Of Engagement Activity 2018
 
Description Laura Dunn - Surrey Vet School Open Day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Undergraduate students
Results and Impact Providing information about a career in research to prospective veterinary students
Year(s) Of Engagement Activity 2018
 
Description Lecture given to University of Surrey MSc Veterinary Microbiology students 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact A 2-hour teaching lecture given to 10 MSc Veterinary Microbiology students at the University of Surrey on 8th December (Lara Harrup)
Year(s) Of Engagement Activity 2017
 
Description Lecture of dynamics of vector-borne diseases 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Undergraduate students
Results and Impact Lecture on the dynamics of vector-borne diseases as part of Part II Pathology: Dynamics of Infectious Diseases course at Univerity of Cambridge
Year(s) Of Engagement Activity 2008,2009,2010,2011,2012
 
Description Lecture on entereic coronaviruses to MSc Students (Surrey) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact A lecture was presented on the pathology, diagnosis and detection of enteric coronaviruses, including virus replication and interaction with the host. The students were engaged and asked/answered question throughout the session. We were invited to repeat the lecture for the subsequent student intakes.
Year(s) Of Engagement Activity 2015,2016,2018
 
Description Lumpy Skin Disease D2R2 profile 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Provided expert opinion to the assessment (D2R2) of the risk of lumpy skin disease virus (LSDV) to the UK.
Year(s) Of Engagement Activity 2017,2018
 
Description MBPAV -presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Molecular Biology and Pathogenesis of avian viruses conference - Oxford 3-4th September 2018. Oral presentation given on drug resistant influenza viruses to approximately 50 scientist. Increased collaborative approaches following presentation.
Year(s) Of Engagement Activity 2018
URL https://microbiologysociety.org/event/society-events-and-meetings/focused-meeting-2018-molecular-bio...
 
Description Mapping antigenic determinants of H9N2 avian influenza viruses and improving vaccines and diagnostics" presented at Foreign Talent Lecture: New strategies and new techniques for the prevention and control of major avian diseases. Shandong Binzhou Animal Science & Veterinary Medicine Academy, Binzhou, China. 6th August 2018. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The focus of the meeting was to improve the control systems against poultry diseases including development of improved vaccines and diagnostics
Year(s) Of Engagement Activity 2018
 
Description Microbiology Today article 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited article titled 'How to Image an Exotic Virus' in special Imaging issue (February 2018).
Year(s) Of Engagement Activity 2018
 
Description Microbiology society- 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Poster presentation of research at annual microbiology society conference. Increased interest in collaborations.
Year(s) Of Engagement Activity 2018
 
Description Newton Agham Researcher Links Workshop on "Novel Vaccines and Diagnostic Technologies Against Emerging and Re-emerging Veterinary Pathogens, Rizal Park Hotel, Manila, Philippines 4-7 February 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The primary aim of this workshop was to forge long-term research partnerships between early-career researchers, livestock industry and national disease control authorities in the UK and the Philippines. The workshop provided information on emerging and next generation diagnostic and vaccine strategies and their utilization to reduce the impact of viral diseases on livestock and poultry.
Year(s) Of Engagement Activity 2019
URL https://www.slideshare.net/zerep_cire/2019-newton-agham-researcher-links-workshop-vaccines-and-diagn...
 
Description Oral presentation at International Pig Veterinary Symposium and International PRRS Symposium, Chongqing, China. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Oral presentation on our PRRS research at the International Pig Veterinary Symposium and International PRRS Symposium, Chongqing, China.
Year(s) Of Engagement Activity 2018
 
Description Organiser of the Animal Genetics and Diseases conference 08 - 10 May 2019 Wellcome Genome Campus, UK. Highlighting recent advances in animal genetics and genomic technologies. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact I am on the organising committee for this conference. The second conference in this series will highlight recent advances in animal genetics and genomic technologies. It will bring together specialists working on the interface of genomics, genetic engineering and infectious disease with the aims of improving animal and human health and welfare.

Novel genomic technologies, mathematical modelling and quantitative genetics approaches, applied to host animals, as well as their pathogens, have transformed the understanding of animal diseases, host-pathogen interactions and epidemiology and their effects on productivity of farmed animal species and food supply chains.

This year's conference will not only put the spotlight on the immune response of host animals and epidemiology but also cover the genetics and genomics of pathogens and the impact of animal-human relationships.

We encourage registrations from researchers, breeders and technical specialists interested in learning and disseminating the latest cutting-edge techniques and methodologies across model species, wildlife, farmed animals and companion animals.
Year(s) Of Engagement Activity 2019
URL https://coursesandconferences.wellcomegenomecampus.org/our-events/animal-genetics-diseases-2019/?dm_...
 
Description Organiser/invited speaker - PhD course in EM, University of Copenhagen 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Workshop for delegates including lectures, seminars and practical sessions. Outcomes are that delegates are able to make informed decisions regarding microscopy techniques about their future projects, and perform sample preparation and operate instruments. Delegates could ask me for advice regarding their projects which sparked questions and discussion within the group on a wide range of multi-disciplinary subjects.
Year(s) Of Engagement Activity 2018
 
Description Outreach video for BTV clinical signs and transmission 2016 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Video by Simon Carpenter and Karin Darpel intended to increase awareness regarding the potential for bluetongue virus re-emergence in the UK. Circa 2000 hits to date.
Year(s) Of Engagement Activity 2016
URL https://www.youtube.com/watch?v=fwJ8zAxiLOE
 
Description Oxford DTP students 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact High level overview of diseases studied [at Pirbright], and the importance of our work, provided to a group of over 30 Oxford DTP students, followed by a networking lunch (29th September 2017).
Year(s) Of Engagement Activity 2017
 
Description PPR-Global Research and Expertise Network talk "Examining the zoonotic potential of PPRV" Vienna 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Gave a talk to the inaugural meeting of the PPR Global Research and Expertise Network (PPR GREN) at IAEA headquarters in Vienna, Austria. Participants included policy makers from the FAO and OIE.
Year(s) Of Engagement Activity 2018
 
Description Pandemic Live (Cheltenham Science Festival) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Approximately 250 attendees at a 1 hour discussion around a simulated virus outbreak scenario (Speakers Fry; Carpenter; Beard; Hatchett). Followed by question and answer session.
Year(s) Of Engagement Activity 2018
URL https://www.cheltenhamfestivals.com/science/whats-on/2018/pandemic-live/
 
Description Participant in IDEAS arboviruses workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Participated in discussions and breakout groups, formed contacts. Planned future meetings on minimum reporting standards in insect infection studies (now funded and scheduled for 2018).
Year(s) Of Engagement Activity 2017
URL http://ideas.princeton.edu/workshop-for-2017/
 
Description Participation in Understanding Animal Research Video 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Interviewed and filmed by Understanding Animal Research as part of their 360 degree tour of UK animal facilities (http://www.labanimaltour.org/)
Year(s) Of Engagement Activity 2017
URL http://www.labanimaltour.org/
 
Description Participation in student day at the Pirbright Institute 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Student open day was participated by postgraduate students registered at several Universities, and scientists from Pirbright institute. Students were given a chance to discuss their research activities and future plans with senior scientists. Due to high interest from the students, the institute has decided to organize another open day.
Year(s) Of Engagement Activity 2016
 
Description Pig and Poultry Fair 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Discussed Institute research with pig and poultry farmers, related industry and the general public. Received requests for more information related to research, business and studentships.
Year(s) Of Engagement Activity 2018
URL https://www.pigandpoultry.org.uk/
 
Description Pirbright Institute stall at LEAF Open Farm Sunday 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Hosting a Pirbright Institute stall at the LEAF Open Farm Sunday, held at the Leckford Estate, The Waitrose Farm, at Stockbridge in Hampshire on Sunday 11 June 2017.

Open Farm Sunday is a day when farms across the country open their doors to the public to show them what it means to be a farmer and for the public to see firsthand how their food is produced.

The Pirbright Institute was part of the "Science on the Farm" stand, together with BBSRC and other bioscience institutes to tell people about the work carried out and how this helps support farmers and protect the UK's food supply and the wider economy.
Year(s) Of Engagement Activity 2017
 
Description Pirbright Pride day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Set up a stand at the described our research, engaged with policymakers, industry and participants from other organizations and distributed leaflets.
Year(s) Of Engagement Activity 2015
 
Description Plenary speaker - Electron Microscopy Cryo-techniques as Tools for Elucidating Biological Processes, University of Minas Gerais, Brazil 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact I was personally invited to talk about imaging the cell biology of host-virus interactions. I was available throughout the associated workshop to provide advice on delegates projects relating to microscopy. These talks sparked discussions and more questions. I was able to increase my network of connections further during this visit to Brazil.
Year(s) Of Engagement Activity 2018
 
Description Population Biology of Vector-Borne Diseases Symposium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation on "Population biology of Culicoides-borne viruses in Europe" at symposium held at University of Georgia Athens on 24 February 2018
Year(s) Of Engagement Activity 2018
 
Description Postdocteral scientist - oral presentation at the 12th Annual meeting of Epizone (joint with 11th International Congress for Veterinary Virology, ESVV 2018) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Postdoctoral scientists abstract submission was selected for oral presentation. Project results obtained at the time were presented to a highly interested and engaging audience of more than 250 scientists, veterinarians, students and policymakers.
Year(s) Of Engagement Activity 2018
URL https://www.epizone-eu.net/en/Home/News/show/Abstract-book-EPIZONEESVV-meeting-now-online-.htm
 
Description Poster presentation: European Veterinary Immunology Workshop, Utrecht, The Netherlands 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact David Goldeck (post-doctoral scientist) gave a poster presentation on our studies to isolate PRRSV-neutralising monoclonal antibodies from immune pigs.
Year(s) Of Engagement Activity 2018
 
Description Preclinical detection of foot-and-mouth disease 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Interview with Veterinary Times about work on preclinical detection of foot-and-mouth disease and its potential impact on future control strategies
Year(s) Of Engagement Activity 2017
URL https://www.vettimes.co.uk/news/pre-clinical-method-a-step-closer-in-fmdv-prevention/
 
Description Preparation of presentation on African swine fever clinical signs and pathogenesis 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Prepared a presentation on African swine fever clinical signs and pathogenesis aimed at making farmers and veterinary practitioners aware. Presentation made available publically on the APHA, DEFRA and Pirbright websites. A follow up video was made by APHA and training for APHA veterinary services is planned
Year(s) Of Engagement Activity 2018
URL http://apha.defra.gov.uk/documents/surveillance/diseases/african-swine-fever-images.pdf
 
Description Presentation at Avian viruses focussed meeting - Sept 2018 ND 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Presentation of data as an offered paper at the molecular biology and pathogenesis of avian viruses meeting, Oxford Sept 2018.
Year(s) Of Engagement Activity 2018
 
Description Presentation at Inter-institute Bioimaging networking meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact An event was held to enable improved collaboration opportunities between scientists working with bioimaging techniques at the different research institutes within the UK. I presented data from the last 10 years describing our work characterising replication organelles induced by IBV, describing the different techniques and approaches we have used and the outlook for the future. The talk aimed to showcase the bioimaging facilities at Pirbright to encourage new collaborations.
Year(s) Of Engagement Activity 2018
 
Description Presentation to BBSRC Executive Board 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact I presented our research to the BBSRC Executive Board when they visited The Pirbright Institute in September 2018 and discussed the impacts of our work..
Year(s) Of Engagement Activity 2018
 
Description Presentation to The Pig Veterinary Society 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation to make pig veterinarians aware of African swine fever
Year(s) Of Engagement Activity 2017
URL http://www.pigvetsoc.org.uk/
 
Description Presentation: Culicoides as vectors of arboviruses 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Keynote lecture given to veterinary scientists and farmers. Performed as part of the World Buiatrics Conference 2016 and video of presentation available to members.
Year(s) Of Engagement Activity 2016
URL http://www.wbc2016.com/
 
Description Provided information to Podcast This week in Virology about African swine fever virus spread in wild boar 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact E-mail correspondence providing advice to presenters of TWIV This week in Virology Podcast.
Year(s) Of Engagement Activity 2019
URL http://www.microbe.tv/twiv/twiv-532/
 
Description Public engagement organized at Oxford 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Set up a stand at the event, a museum at Oxford, and discussed and described research activities within the Institute with public. Set up demonstrations from some biological specimens and distributed leaflets and questionnaire.
Year(s) Of Engagement Activity 2015
 
Description Reddit AMA (Ask Me Anything) on vector-borne diseases 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Took part in a Reddit Ask Me Anything (AMA) on vector-borne diseases. AMAs are a question-and-answer format activity where an individual expert or panel of experts answers questions from the public for a specified duration. We received a large number of questions and the parent post received 493 upvotes, indicating an absolute minimum of 493 participants (and very probably more), so I have given the estimated audience as 500+.
Year(s) Of Engagement Activity 2017
URL https://www.reddit.com/r/science/comments/6he8go/aaas_ama_hi_were_maria_elena_bottazzi_marcia/
 
Description Reverse genetics seminar to MSc students 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact A seminar was presented describing reverse genetics of viruses, including infectious bronchitis virus and the application of reverse genetics in research. The students were interested and engaged, participating in activities and asking questions. We were invited to present the seminar in subsequent years for new student intakes.
Year(s) Of Engagement Activity 2013,2014,2015,2016,2018
 
Description Royal Institution Christmas Lectures Family Day - LA 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Six Pirbright staff/students ran an all-day exhibit on gene editing and mosquitoes at the Royal Institution About 270 participants visited our stand; wide range of comments, questions, discussion and feedback
Year(s) Of Engagement Activity 2019
 
Description STEM Day - Speed interviews and Careers Day 2018 - BA 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Stimulating increased interest in research
Year(s) Of Engagement Activity 2018
 
Description Scheduled Twitter session with University of Nottingham students on professional skills for biosciences 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Undergraduate students
Results and Impact Hour-long Twitter chat on Friday 12th May with biotechnology students, microbiology students, animal science students interested in animal diseases and animal welfare and behaviours and agriculture students interested in livestock.
Year(s) Of Engagement Activity 2017
URL https://twitter.com/search?q=%23biosciprofskills
 
Description School visit 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Met and discussed A level students in small groups (3 students at the time) and discussed different aspects of my work as a scientist.
Year(s) Of Engagement Activity 2015
 
Description School visit (Farnborough) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Gave a presentation to a group of students about research performed at the Pirbright Institute and discussed various aspects of scientists' work.
Year(s) Of Engagement Activity 2018
 
Description Site tour with Department of Trade and Industry 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Tour/site visit with Department of Trade and Industry (25 people attending)
Year(s) Of Engagement Activity 2017
 
Description St Andrew's Catholic School visit to Pirbright 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact College students visited the Institute to learn about lab designs. They were given talks about the equipment and labs and then toured around the labs at Pirbright. Students were highly interested about our facilities and the work we are conducting at The Institute.
Year(s) Of Engagement Activity 2016
 
Description Surrey County Show 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The Surrey County Show is an agricultural show in Guildford that is visited by the general public. The Pirbright Institute had a stand with various activities for visitors to take part in and explain our science to a wide audience. Giulia spent a day working on the stand and spoke with many children and adults about her work at Pirbright to change public attitudes and stimulate increased interest in research.
Year(s) Of Engagement Activity 2018
 
Description Surrey County Show 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Stall at Surrey County Show, engage with the public where they can ask any questions they have about the work we do. This sparks discussions, and an increase in knowledge of the general public. I invited the Lord Lieutenant of Surrey to our stand, with whom I have built a solid relationship. This has lead to engagement of his office with the Institute, for example the visit of HRH Princess Anne to Pirbright in 2017.
Year(s) Of Engagement Activity 2018
 
Description Surrey Open day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact Described the research activity of the Pirbright Institute for students from school, graduate and postgraduate students, and provided information on research facilities in the institute.
Year(s) Of Engagement Activity 2017
URL https://www.surrey.ac.uk/opendays/vet
 
Description Surrey vet school open day - MJB 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact The event was an open day for prospective students for the University of Surrey vet school. The course includes a research placement, which can be conducted at Pirbright. Therefore there was a stand from Pirbright to describe the research we perform generally as well as a discussion of our specific research. The audience were generally interested and the information helped inform them when selecting a university course.
Year(s) Of Engagement Activity 2018
 
Description Sutton College Lecture (Enjoy your retirement) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Talk to group on virus outbreaks (Enjoy your retirement) - 16 people & class coordinator. Included simulation of a virus outbreak.
Year(s) Of Engagement Activity 2019
 
Description Symposium for WRLFMD 60th Anniversary 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact During November, the Pirbright Institute hosted a two-day symposium attended by over 100 FMD scientists to celebrate the 60-year anniversary of the establishment of the World Reference Laboratory for Foot-and-Mouth Disease (WRLFMD).

The meeting was opened by Christine Middlemiss (UK, Chief Veterinary Officer), Matthew Stone (Deputy Director General of the OIE) and Keith Sumption (from FAO/EuFMD). Subsequent scientific sessions reviewed the current activities of the WRLFMD (and OIE/FAO FMD Laboratory Network: https://www.foot-and-mouth.org), and discussed new opportunities to monitor, diagnose and control FMD by applying knowledge from fundamental research projects that aim to understand the pathogenesis, host responses and epidemiology of the disease.

Talks from invited speakers and WRLFMD staff were within four themes of (i) Risks & Threats, (ii) Diagnostic Innovation, (iii) Pathogenesis & Immunity and (iv) FMD Control with a Focus on Vaccination. These presentations showcased the synergy between fundamental/basic science and the on-going global surveillance activities undertaken by FMD Reference Laboratories.

In the evening, the meeting delegates (including past and present members of the WRLFMD) were royally entertained at a local hotel by after-dinner "trips down memory lane" talks from Nick Knowles and Dave Rowlands that highlighted key events and personalities that have shaped the history of work at Pirbright.
Year(s) Of Engagement Activity 2018
URL https://www.wrlfmd.org/60th-anniversary
 
Description Taiwan -UK Partnering Award: Surveillance of influenza viruses 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Attended the International Flu Virus Symposium for Celebrating IPM 47th Anniversary" in Tri-Service General Hospital in Taipei, Taiwan.

Tri-Service General Hospital address:
No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City 114, Taiwan (R.O.C.)

Invited speaker for medical staff and research scientists.
Year(s) Of Engagement Activity 2019
URL https://www.cdc.gov.tw/rwd/english
 
Description Talk as part of the University of Veterinary Medicine (Vienna) doctoral school "Infectious Diseases of Pig and Poultry" 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Talked about the Pirbright Institute's work on African swine fever virus to researches in Veterinary Medicine (Virology and Immunology) in Vienna.
Year(s) Of Engagement Activity 2018
 
Description Talk to students studying Animal Health and Management at Duchy College 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Undergraduate students
Results and Impact Talk hosted at the Institute for 12 student studying Animal Health and Management at Duchy College.
Year(s) Of Engagement Activity 2017
 
Description Talk to students studying BSc in Animal Behaviour and Welfare at Merrist Wood College 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact Talk hosted at the Pirbright Institute for 13 undergraduate students studying Animal Behaviour and Welfare.
Year(s) Of Engagement Activity 2017
 
Description Teentech 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact The annual Teentech student science event in Guildford aims to encourage teenagers to consider science subjects and science careers. Our stand had considerable interest from the schoolchildren who were very enthusiastic. The event stimulated an increased interest in science and research.
Year(s) Of Engagement Activity 2016,2019
 
Description Teentech Guildford - ND 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Teentech is an event held for students from a range of local school who have an interest in science to experience the range of scientific activities that could be open to them for future careers. Students in small groups rotate around stands at the event to perform activities at each station, guided by scientists. The Pirbright stand was demonstrating the principle of genetic modification of mosquitos. The children were very interested in the exhibit and asked lots of questions.
Year(s) Of Engagement Activity 2013,2019
 
Description Television interview Ulaanbaatar 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact I was interviewed by UB television while on a collaborative visit to the State Central Veterinary Laboratory in Mongolia. I spoke about the collaboration between The Pirbright Institute and the SCVL, and how this benefits the Mongolian agricultural sector.
Year(s) Of Engagement Activity 2017
 
Description The Hurst careers event - HJM 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact The Hurst school held a careers event for GCSE students to attend throughout the day. The Pirbright stand contained a variety of engagement activities to demonstrate the research we perform and to stimulate discussion. The students seemed interested in the activities and those more interested in a science career asked a variety of questions about the research and entry into scientific research as a career.
Year(s) Of Engagement Activity 2018
 
Description The Pirbright Village Duck Fair held on 16 June 2018 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Local Village Fair, interaction with local residence to expanse research aims and activities of The Pirbright Institute and benefits to UK and around the globe to prevent and control infectious diseases of animals and humans.
Year(s) Of Engagement Activity 2018
 
Description This Week In Virology Podcast 532: Morbillivirus had a little lamb 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Our research paper on morbillivirus host-range in Journal of Virology was highlighted for in-depth discussion on this episode of TWIV where they spent 30+ minutes talking about the work and its potential impact. This podcast is the number one podcast in virology and listened to across the globe.
Year(s) Of Engagement Activity 2019
URL http://www.microbe.tv/twiv/twiv-532/
 
Description This week in Virology: 533: Recurring threads 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Following our paper being highlighted on the previous edition of TWIV I wrote a letter to further the discussion of this subject and clarify some technical points on The Pirbright Institute. This was read out as part of the podcast and discussed.
Year(s) Of Engagement Activity 2019
URL http://www.microbe.tv/twiv/twiv-533/
 
Description Tillingbourne School bug hunt - ND 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Primary school students were involved in an event to identify insects in the school grounds.
Year(s) Of Engagement Activity 2018
 
Description Tillingbourne School science event - ND 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Tillingbourne School held a science event for year 3 students to explore different aspects of science including smell, acid & alkali, magnetism etc. Nicole was based at the microscopy station helping children to view samples under the microscope, explain what they were looking at and answer any questions to children asked. The children were highly engaged and interested in the exhibit.
Year(s) Of Engagement Activity 2018
 
Description Tour of Philip Mellor Insectary (Country Land and Business Association) 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Third sector organisations
Results and Impact Tour of Philip Mellor Insectary with Country Land and Business Association (20 people)
Year(s) Of Engagement Activity 2017
 
Description U3A talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on influenza virus research at The Pirbright Institute for the local University of the Third Age group, approx. 50 people aged 65 years + all with an interest in science.
Year(s) Of Engagement Activity 2018
URL https://cu3asandt.wordpress.com/2018/09/23/meeting-2nd-october/
 
Description UK vector meeting 2018 (Organising committee; Chair) (December; John Innes Centre, UK) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Chaired and helped organise meeting on UK Vector-borne Diseases as part of committee. Included reviewing talks and inviting speakers.
Year(s) Of Engagement Activity 2018
URL http://www.hpruezi.nihr.ac.uk/media/29013/master-draft-vbd-programme-with-titles-oct18_.pdf
 
Description UK-China Philippines-Thailand Swine and Poultry Research Initiative project kick-off workshop" at China Agriculture University, Beijing, 26th-28th September 2018. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Emerging new approaches were discussed for prevention and control of infectious diseases affecting swines and poultry.
Year(s) Of Engagement Activity 2018
 
Description Understanding Antigenic Diversity, Zoonotic potential and immunological prevention of avian influenza viruses affecting poultry. Presented at "UK-China Philippines-Thailand Swine and Poultry Research Initiative project kick-off workshop" at China Agriculture University, Beijing, 26th-28th September 2018. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Meeting focus was to share research plans funded under "UK-China-Philippines-Thailand Swine and Poultry Research Initiative". Research projects investigate pathogens, zoonotic pathogens or "commensals" associated with food safety issues affecting poultry and swine.
Year(s) Of Engagement Activity 2018
URL https://bbsrc.ukri.org/funding/filter/joint-swine-poultry-initiative/
 
Description University of Surrey Vet School Open Day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact Institute stand at Surrey Vet School - introducing the institute to prospective vet students
Year(s) Of Engagement Activity 2018
 
Description Vet School Open Day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact University of Surrey School of Veterinary Medicine Open Day - introduced The Pirbright Institute and the research we conduct to prospective students and parents.
Year(s) Of Engagement Activity 2018
 
Description Vet Times 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Information on research activity of Avian Immunology group at the Pirbright Institute
Year(s) Of Engagement Activity 2018
 
Description Veterinary Times article on morbillivirus vaccines. 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact I was interviewed by a journalist from The Veterinary Times about our recent Journal of Virology research paper on morbillivirus host-range. This was then written up for the next edition of this publication.
Year(s) Of Engagement Activity 2019
URL https://www.vettimes.co.uk/news/scientists-multi-purpose-ppr-vaccine-closer-to-completion/
 
Description Video on African swine fever clinical signs for APHA 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Video prepared to inform farmers and vets about African swine fever virus clinical signs
Year(s) Of Engagement Activity 2018
URL https://www.youtube.com/watch?v=z4kSR-wMO4M&feature=youtu.be
 
Description Virtual video tour of the animal facilities in Pirbright 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Contributed to public understanding of animal research by being interviewed on the virtual video tour of the animal facilities in Pirbright - one of only four such initiatives in the UK.
Year(s) Of Engagement Activity 2017
 
Description Winston Churchill Careers Fair. Winston Churchill School, Hermitage Road, St Johns, Woking, Surrey, GU21 8TL 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact AS attended and presented at this event to stimulate increased interest in science and research.
Year(s) Of Engagement Activity 2018
 
Description Woking High School Careers Fair -18th September 2018 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Career fair attended by approx. 50 school aged children. Pirbright offered advice and information about the different career streams available at a research institute.
Year(s) Of Engagement Activity 2018
 
Description Workshop 1: Minimum Information for Reporting Arthropod Infection Studies 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A workshop was held as part of the VectorBiTE RCN annual meeting at Asilomar in CA. Attendance was roughly 60 people, mostly users of data resulting from experimental arthropod infection studies or arthropod ecological datasets. AW gave a presentation describing the objectives of the grant and then we formed breakout groups to discuss potential factors to report and their importance for different categories of users. The feedback was used to review and update the draft standards document before the second workshop as ASTMH's Trop Med meeting in New Orleans in October.
Year(s) Of Engagement Activity 2018
 
Description Workshop 2: Minimum Information for Reporting Arthropod Infection Studies 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A workshop was organised in collaboration with members of the ASTMH's Advisory Committee on Arthropod-borne Viruses (ACAV) at the start of the 2018 Trop Med annual meeting and was advertised via social media and society and project mailing lists. Around 30 people attended, mostly from the US but with representation from Asia, Europe and South America, and a mixture of senior academics, junior faculty and students. AW gave a brief introduction to the objectives of the workshop and AW, assisted by LH (a postdoc at Pirbright), helped participants pilot the questionnaire before its formal launch. Feedback was positive and used to refine the questionnaire before it was launched in November. As a result of specific points raised in the feedback, the survey was translated into French and Spanish and these versions were launched simultaneously to support involvement by a broader audience.
Year(s) Of Engagement Activity 2018
 
Description Workshop 3: Minimum Information for Reporting Arthropod Infection Studies 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact A workshop was organised during the biennial UK VBD meeting in Norwich to improve awareness of the survey and increase completion. A short presentation was given by LH, a postdoc at Pirbright who has been assisting with the development of the questionnaire and standards documentation (as AW is leaving Pirbright in December) and then breakout groups formed to discuss particular challenges and any suggested changes as well as pathways to increasing the chances of uptake of the resulting guidelines. The feedback was recorded and will influence the resulting report/manuscript.
Year(s) Of Engagement Activity 2018
 
Description Workshop with MSc students in Veterinary Microbiology 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Both PI and postdoctoral scientists employed on projects participated in a 1 week workshop of MSc students from the University of Surrey including training activities within the high containment facilities
Year(s) Of Engagement Activity 2017,2018,2019
 
Description World Zoonosis Day 2018 - web story 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Contributed to an article from our institute on World Zoonosis Day highlighting the importance of research in this area.
Year(s) Of Engagement Activity 2018
URL https://www.pirbright.ac.uk/news/2018/07/pirbright-scientists-are-developing-vaccine-candidates-anim...