Functional characterization of phytoplasma effector proteins and the role of salivary gland proteins in plant colonization of aphids
Lead Research Organisation:
John Innes Centre
Department Name: Contracts Office
Abstract
The goal of this project is to identify and characterize plant pathogen and pest virulence (effector) proteins that manipulate plants to become better hosts for these pathogens and pests. We have established genome sequence annotation pipelines to identify candidate effector proteins from phytoplasmas (bacterial plant pathogen transmitted by phloem-feeding leafhoppers) and aphids (phloem-feeding insects that transmit a variety of plant diseases).
Some phytoplasmas, including Aster Yellows strain Witches’ Broom (AY-WB), have broad plant host ranges. We have identified several effector proteins that target plant cell nuclei and change plant morphology comparable to that of AY-WB-infected plants. These morphological changes are beneficial for the leafhopper vector, which is required for dissemination of phytoplasmas in nature. The effector protein genes are encoded on potential mobile units (PMUs) that are abundant in the genomes of phytoplasmas and appear to have had major influence on phytoplasma evolution and diversification. Some PMUs are predominantly expressed during AY-WB infection of plants and others in insects. This project will lead to the functional characterization of at least one AY-WB effector.
The majority of plants are resistant against the majority of aphid species, and only some aphid species, such as the generalist Myzus persicae, can feed from multiple plant host species. Insects release a variety of proteins into the plant phloem in their saliva. These proteins can benefit the insect by reprogramming plant development, but may also play a role in plant resistance to insect attack. This project will focus on aphid interactions with Arabidopsis and crop plants. The project will use the expanding genomics resources for Myzus spp. and Arabidopsis and the JIC infrastructure resources to better understand aphid-plant interactions. The aphid salivary proteome will be investigated and the impact of some secreted proteins on plant responses determined.
Some phytoplasmas, including Aster Yellows strain Witches’ Broom (AY-WB), have broad plant host ranges. We have identified several effector proteins that target plant cell nuclei and change plant morphology comparable to that of AY-WB-infected plants. These morphological changes are beneficial for the leafhopper vector, which is required for dissemination of phytoplasmas in nature. The effector protein genes are encoded on potential mobile units (PMUs) that are abundant in the genomes of phytoplasmas and appear to have had major influence on phytoplasma evolution and diversification. Some PMUs are predominantly expressed during AY-WB infection of plants and others in insects. This project will lead to the functional characterization of at least one AY-WB effector.
The majority of plants are resistant against the majority of aphid species, and only some aphid species, such as the generalist Myzus persicae, can feed from multiple plant host species. Insects release a variety of proteins into the plant phloem in their saliva. These proteins can benefit the insect by reprogramming plant development, but may also play a role in plant resistance to insect attack. This project will focus on aphid interactions with Arabidopsis and crop plants. The project will use the expanding genomics resources for Myzus spp. and Arabidopsis and the JIC infrastructure resources to better understand aphid-plant interactions. The aphid salivary proteome will be investigated and the impact of some secreted proteins on plant responses determined.
Organisations
- John Innes Centre, United Kingdom (Collaboration, Lead Research Organisation)
- Royal Horticultural Society, United Kingdom (Collaboration)
- Chinese Academy of Sciences (Collaboration)
- Wageningen University & Research (Collaboration)
- University of St Andrews, United Kingdom (Collaboration)
- Sultan Qaboos University (Collaboration)
- Academia Sinica (Collaboration)
- University of Liverpool, United Kingdom (Collaboration)
- Forest Research, United Kingdom (Collaboration)
- University of Lisbon (Collaboration)
- CGIAR (Collaboration)
- SESVanderhave (Collaboration)
- University of Wisconsin Madison, United States (Collaboration)
- International Livestock Research Institute (ILRI) (Collaboration)
- University of Stirling, United Kingdom (Collaboration)
- International Centre of Insect Physiology and Ecology (ICIPE) (Collaboration)
- University of Oxford, United Kingdom (Collaboration)
- Chinese Academy of Agricultural Sciences (Collaboration)
- Earlham Institute, NORWICH (Collaboration)
- National Research Council CNR - Italy (Collaboration)
- Fera Science Limited, LONDON (Collaboration)
- German Centre for Integrative Biodiversity Research (Collaboration)
- Stellenbosch University, South Africa (Collaboration)
- University of East Anglia, United Kingdom (Collaboration)
- Institute of Plant Protection, National Research Institute (Collaboration)
- Kyoto University, Japan (Collaboration)
- Universidade de São Paulo (Collaboration)
- East Malling Research, United Kingdom (Collaboration)
- Department for Environment, Food and Rural Affairs (Defra) (Collaboration)
- University of Sussex, United Kingdom (Collaboration)
- UK Ctr for Ecology & Hydrology fr 011219 (Collaboration)
- University of Zagreb (Collaboration)
- Syngenta International AG (Collaboration)
- Liverpool School of Tropical Medicine (Collaboration)
- Science and Advice for Scottish Agriculture (Collaboration)
- University of Salford, United Kingdom (Collaboration)
Publications
Ammar El-D
(2011)
Spiroplasma-like organisms closely associated with the gut in five leafhopper species (Hemiptera: Cicadellidae).
in Archives of microbiology
Ammar El-D
(2009)
Cellular and molecular aspects of rhabdovirus interactions with insect and plant hosts.
in Annual review of entomology
Bai X
(2009)
AY-WB phytoplasma secretes a protein that targets plant cell nuclei.
in Molecular plant-microbe interactions : MPMI
Bai X
(2009)
Transcriptomic analysis of the entomopathogenic nematode Heterorhabditis bacteriophora TTO1.
in BMC genomics
Bos JI
(2010)
A functional genomics approach identifies candidate effectors from the aphid species Myzus persicae (green peach aphid).
in PLoS genetics
Cañizares M
(2015)
Arabidopsis thaliana , an experimental host for tomato yellow leaf curl disease-associated begomoviruses by agroinoculation and whitefly transmission
in Plant Pathology
Chang HH
(2015)
Complete Genome Sequence of "Candidatus Sulcia muelleri" ML, an Obligate Nutritional Symbiont of Maize Leafhopper (Dalbulus maidis).
in Genome announcements
Coleman AD
(2015)
Persistence and transgenerational effect of plant-mediated RNAi in aphids.
in Journal of experimental botany
Coleman AD
(2014)
Silencing of aphid genes by feeding on stable transgenic Arabidopsis thaliana.
in Methods in molecular biology (Clifton, N.J.)
| Title | Produced a video |
| Description | Generated a video explaining how plants become zombies and posted this on YouTube. The videos features researchers explaining the research and doing experiments, and plants with disease symptoms and insect pests. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2014 |
| Impact | The video was released as part of a press release for the MacLean et al., 2014. PLoS Biol publication. It received attention from journalists worldwide who covered the findings in newspapers, local journals and prestigious news letters to engage the general public. |
| URL | https://www.youtube.com/watch?v=QGTESwEeqsM&feature=youtu.be |
| Title | Video Abstract for Genome Biology publication |
| Description | Genome Biology created a video abstract to explain the science described in the Genome Biology to students. The video shows animation of an aphid changing plant hosts with a narrator who explains what happens in the aphid upon the host change. The video was posted on YouTube. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2017 |
| Impact | So far the video had 488 views on YouTube, and 9 viewers liked the video and none disliked the video. The video has likely increased the amount of attention the Genome Biology article received by different media (current Altmetric attention score of the paper is 110). |
| URL | https://www.youtube.com/watch?v=EKy_SuaFKMk |
| Title | Video showing how aphids sense aphid attack |
| Description | We launched a short video showing the method by which we can monitor the calcium elevations that occur in a leaf during aphid probing. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2018 |
| Impact | The video will be understood by a wide audience. |
| URL | https://www.youtube.com/watch?v=CK2iIPfcnvo |
| Description | The funding in this project has been used to generate preliminary data for obtaining additional funding. It enabled continuing projects between funding cycles and starting new ones and to startup new collaborations. For aphids, we generated genome, transcriptome and proteome data that led to the discovery of effector proteins that aphids use to modulate plant processes and successfully colonize plants. We found that the effector proteins are present in the saliva of aphids and that these proteins are inoculated into plants. One effector was located in the cytoplasm of plant cells (Mugford et al., 2017. MPMI). We found that this effector suppresses plant defense responses (Bos et al., 2010. PLoS Genetics; Drurey et al., 2018. Biorxiv). We generated evidence that this effector is conserved among sap-feeding insects (Drurey et al., 2018. Biorxiv) and elucidated candidate plant targets. These findings were communicated to colleagues of the sugarbeet breeding company SESVanderHave who directly funded or co-funded (via a BBSCR-LINK) further research on aphid-plant interactions that includes functional analyses of other aphid effectors and their targets. This collaboration is still active. We used funds in this project to develop the RNA interference (RNAi) technology to knock down gene expression in aphids. We showed that we can knock down gene expression in aphids via plant-mediated RNAi (Pitino et al., 2013. PLoS One; Coleman et al., 2015. JXB). We also generated a first genome assembly and annotation of the green peach aphid Myzus persicae in collaboration with David Swarbreck at TGAC (now the Earlham Institute). These data led to collaborations with Syngenta Ltd via a BBSRC-IPA grant that is focused on using aphid genome sequence information and RNAi for studying pesticide resistance and plant host adjustment mechanisms in aphids. This collaboration with Syngenta has progressed very well and led to a second BBSRC-IPA grant that started last year. Syngenta is using our findings to inform their strategies to develop RNAi-mediated pest control technologies. The research on RNAi also provided preliminary data to further develop the RNAi technology for whitefly that was funded by the Bill and Melinda Gates Foundation, and further funding of research on aphids and whiteflies via iCASE studentships. We also used funding from this research project to investigate how plants respond to aphid feeding. We found that plants have specific receptors that detect aphid elicitors leading to a specific plant defense response in the plant (Prince et al., 2014. Plant Physiol.). We identified an aphid effector that suppresses this plant defense response (Mugford et al., 2017. MPMI; Drurey et al., 2018. Biorxiv). This work instigated collaborations with colleagues at the John Innes Centre and the University of Madison, Wisconsin, USA, and the funding of PhD studentship to further investigate the nature of the plant defense response. We developed methods to detect local calcium bursts that surround the aphid feeding site and identified plant factors that regulate these calcium elevations (Vincent et al., 2017. Plant Cell). The work resulted in a successful PhD student thesis and defense and is taken further by two PhD students in the lab. One of these students won a prestigious Gatsby fellowship to fund his PhD. The other PhD student has initiated collaborations with colleagues at The Sainsbury Laboratory and at Kyoto University, Japan. Therefore, this project has led to collaborations with colleagues within the JIC and at other research centers in Norwich, USA and in Japan. The funds also contributed to research that identified and characterized effectors from Phytoplasma. Phytoplasma colonize their host plants and insect vectors. We found that 65% of the Phytoplasma effector genes are upregulated when these bacteria colonize the host plant, whereas 35% of the effector genes are upregulated in the insect vector (MacLean et al., 2011. Plant Physiol). This project contributed to research that identified plant targets for some of Phytoplasma effectors that are upregulated in the plant (Sugio et al., 2011. PNAS; Sugio et al., 2014. New Phytol; MacLean et al., PLoS Biol) and to the demonstration that the effectors suppress plant defense responses to the insect vectors (Sugio et al., 2011. PNAS; MacLean et al., 204; Orlovskis et al., 2016. Front. Biotic Interact.). Based on these data we were successfull at winning a BBSRC-FAPESP grant and the prestigous Human Frontier Science Program (HFSP) research grant, and a Marie Curie fellowship (to Allyson MacLean) and a Newton fellowship (to Adi Kliot). The BBSRC-FAPESP grant was a collaboration with colleagues in Brazil on the maize-pathogenic Maize bushy stunt phytoplasma. A PhD student in my lab visited my collaborator in Brazil and we published part of this research (Orlovkis et al., 2017. Annals Botany). The HFSP grant is for an interdisciplinary project with collaborators in the USA, Poland, The Netherlands and the UK, and involves mechanistic modelling, molecular and biochemistry research, insect assays and field-based work. The writing of several papers to report the outputs of this research is ongoing. Finally, the project enabled the writing of the BRIGIT project and visiting key people to launch this project. |
| Exploitation Route | The project led to collaborations worldwide and with industrial partners, and resources required to start the BRIGIT project that is a consortium of 12 UK research institutions and more thabn 65 researchers. The BRIGIT project involves engagement with policymakers. |
| Sectors | Agriculture, Food and Drink,Chemicals,Education,Environment,Government, Democracy and Justice |
| Description | The research findings discovered in this project provided preliminary data used for obtaining research funding from various sources, including: - 2 x BBSRC-IPA grants that received 10% cash contributions from Syngenta Ltd. - A Marie Curie Postdoctoral fellowship awarded to Dr. Allyson MacLean in my group. - Two research projects directly funded by SESVanderHave. - A BBSRC-FAPESP grant in collaboration with colleagues in Brazil. - A BBSRC-LINK grant with SESVanderHave. - iCASE studentships with SESVanderHave, Oxitec and Syngenta/Liverpool School of Tropical Medicine. - a Bill and Melinda Gates Foundation grant. - A prestigious interdisciplinary Human Frontier Science Program (HFSP) project with collaborators in the USA, Poland, The Netherlands and the UK. - A BBSRC Future Leader Fellowship won by postdoctoral researcher Dr. Thomas Mathers in my group. - A Newton fellowship awarded to Dr. Adi Kliot in my group. - CEPAMS funds to further develop projects with collaborators at CAS and CAAS in China. - JIC Innovation Fund to further develop technologies for a patent application. - Several DTP studentships. - A PhD studentship funded by the Gatsby Foundation. - The BRIGIT consortium project funded by the UKRI Strategy Priority Fund. The above grants have allowed me to generate impact via engaging with industry and (under)graduate students. - My industrial collaborators have used knowledge generated in my group for developing new avenues to control insect pests, including for instance RNAi-mediated strategies and developing markers for breeding crops with increased resistance to pests. My group's interactions with industry have been very productive leading to renewal of contracts and the direct funding of research by industry. - I hosted several undergraduate students in my lab for summer projects and final year research projects. The majority of these students have moved on to pursue a career in science, including obtaining MSc and PhD fellowships. - The majority of PhD students that graduated from my group have careers in science. Several former PhD students are postdoctoral researchers and some lead their own research groups in the UK and other countries. |
| First Year Of Impact | 2007 |
| Sector | Agriculture, Food and Drink,Education,Environment,Government, Democracy and Justice,Culture, Heritage, Museums and Collections,Retail |
| Impact Types | Cultural,Societal,Economic,Policy & public services |
| Description | Co-organized, presented and engaged with stakeholders at government workshop meeting |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Co-organized, presented and engaged with stakeholders at government workshop meeting. Discussed how government should be informed and interact with the project, success of BRIGIT and priorities and future research beyond BRIGIT. Participated in the Xylella preparedness meeting. |
| Description | Hosted colleague from industry for teaching lab technique |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Taught industrial partner specific lab technique. |
| Description | Participated in Plant Health Services Conference, Fera |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Presented about progress made with the BRIGIT project, including tools and information resources that have been developed within the project. Encouraged inspectors and other colleagues that engage with growers and nurseries to engage with BRIGIT consortium members to receive training in identification of insect vectors of Xylella. |
| Description | Project Leader of BRIGIT, a UK-wide consortium to mitigate the risks of Xylella fastidiosa outbreaks in the UK |
| Geographic Reach | Europe |
| Policy Influence Type | Membership of a guideline committee |
| Impact | The BRIGIT consortium includes people from various layers of government, charities, research institutes and industry. The writing of the BRIGIT proposal and activities within BRIGIT so far increased the knowledge of the consortium members about the Xylella pathosystem and how Xylella fastidiosa may spread in the UK and harm the environment. This is likely to influence future regulations to maximize protection of the UK environment. |
| URL | https://www.jic.ac.uk/brigit/ |
| Description | Recruitment if new group leaders at JIC |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Member of recruitment committee that recruited group leaders to the JIC in 2019 and 2020. |
| Description | Recruitment of new head for the Entomology Facility at the institute |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Provided leadership to the JIC Entomology Facility steering committee upon retirement of Facility head and recruitment of a new Facility head. Developed a draft of a business plan, managed Entomology Facility staff in the transition period, developed a position description for the new Facility head, interviewed applicant and successfully recruited a new head. |
| Description | Assess sugarbeet resistance to aphids |
| Amount | £9,870 (GBP) |
| Organisation | Sesvanderhave |
| Sector | Private |
| Country | Belgium |
| Start | 02/2019 |
| End | 02/2020 |
| Description | BBSCR Future Leadership Award awarded to TM |
| Amount | £429,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2021 |
| Description | BBSRC IPA |
| Amount | £962,887 (GBP) |
| Funding ID | BB/R009481/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2021 |
| Description | BBSRC-IPA grant |
| Amount | £1,316,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2021 |
| Description | CAS-JIC collaboration |
| Amount | £120,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2017 |
| End | 03/2020 |
| Description | Cash contribution to IPA grant |
| Amount | £131,700 (GBP) |
| Organisation | Syngenta International AG |
| Sector | Private |
| Country | Switzerland |
| Start | 04/2018 |
| End | 03/2021 |
| Description | Cash contribution to IPA grant |
| Amount | £95,000 (GBP) |
| Organisation | Syngenta International AG |
| Sector | Private |
| Country | Switzerland |
| Start | 10/2014 |
| End | 09/2016 |
| Description | Future Leader Fellowship awarded to Thomas Mathers |
| Amount | £317,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 04/2021 |
| Description | Human Frontier Science Program (HFSP) Research Grant |
| Amount | $1,350,000 (USD) |
| Funding ID | RGP0024/2015 |
| Organisation | Human Frontier Science Program (HFSP) |
| Sector | Charity/Non Profit |
| Country | France |
| Start | 08/2015 |
| End | 07/2019 |
| Description | In kind contribution to LINK grant |
| Amount | £414,657 (GBP) |
| Organisation | Sesvanderhave |
| Sector | Private |
| Country | Belgium |
| Start | 04/2016 |
| End | 09/2019 |
| Description | Institute Innovation Funds |
| Amount | £124,000 (GBP) |
| Organisation | John Innes Centre |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 12/2020 |
| Description | JIC-CAAS collaboration funds |
| Amount | £100,000 (GBP) |
| Organisation | John Innes Centre |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 12/2018 |
| Description | PhD Student Fellowship |
| Amount | £23,977 (GBP) |
| Organisation | Gatsby Charitable Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 09/2022 |
| Description | The Royal Society Kohn Fellowship awarded to Adi Kliot |
| Amount | £65,000 (GBP) |
| Organisation | The Royal Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 10/2018 |
| Description | US Partnership Award |
| Amount | £50,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2016 |
| End | 06/2018 |
| Description | iCASE PhD studentship |
| Amount | £27,800 (GBP) |
| Funding ID | 1805607 |
| Organisation | John Innes Centre |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 09/2020 |
| Description | iCASE PhD studentship |
| Amount | £12,400 (GBP) |
| Organisation | Oxitec Ltd |
| Sector | Private |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 09/2019 |
| Description | iCASE studentship with Oxitec |
| Amount | £20,000 (GBP) |
| Organisation | Oxitec Ltd |
| Sector | Private |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 10/2019 |
| Title | BS-seq analyses on aphids |
| Description | We optimized bisulphite sequencing of aphids, including library construction, sequencing and data analyses. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Providing a useful method and strategy to the research community. |
| Title | Developed a collection strategy for Xylella insect vector population structure analyses in the UK |
| Description | Developed strategy and coordinated sampling insect vector populations at at least four different habitats at 5 locations in the UK at four time points. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | Assessment of population structure of Xylella fastidiosa insect vectors in the UK. The data can be used to model Xylella fastidiosa spread in the UK if the pathogen is introduced. |
| Title | Genome assembly |
| Description | Developed strategies to improve the assembly of aphid genomes that includes the identification and removal of contigs derived from microbial organisms that are abundantly present in aphids. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Assisted colleagues in the US with improving genome assembly of the soybean aphid. |
| Title | Insect cell based expression system |
| Description | We successfully setup insect cell (Sf9 cells)-based protein production system using the baculovirus bac-to-bac method. Different purification methods were tried out to obtain enough protein for crystallography. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | At least two labs at JIC and TSL are using the system. |
| Title | Nanopore for aphids |
| Description | We optimized DNA isolation methods for nanopore sequencing of aphid genomes. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | We are able to improve aphid genome assemblies. |
| Title | Developed and launched SapFeedersHub |
| Description | Database that provides access via an Ensemble platform to genome sequences and annotations of insect species of the order Hemiptera, including aphids, leafhoppers, planthoppers and froghoppers/spittle bugs. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | Colleagues can download sequence data and annotations of economically important insect pests, including for instance the Xylella insect vector Philaenus spumarius. Data can be used for population structure analyses and GWAS to study genomic regions involved in insect phenotypes or host preference. |
| URL | http://sapfeedershub.jic.ac.uk/index.html |
| Description | Collaboration with East Malling Research |
| Organisation | East Malling Research |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | We are sequencing and annotating the genome of the woolly apple aphid, a serious pest of apple trees |
| Collaborator Contribution | The collaborator provided frozen aphids for genome and RNA sequencing |
| Impact | We will obtain the complete genomes and transcriptomes of the woolly apple aphid, which is in a distinct clade in the aphid phylogenetic tree and useful for comparative genome analyses among aphids. |
| Start Year | 2018 |
| Description | Collaboration with Institute for Sustainable Plant Protection, Bari, Italy |
| Organisation | National Research Council |
| Department | Institute for Sustainable Plant Protection |
| Country | Italy |
| Sector | Public |
| PI Contribution | I invited colleague at Institute for Sustainable Plant Protection to attend and contribute a talk at the BRIGIT consortium meeting of July 2019, Edinburgh. The colleague was also invited to give a talk at the BRIGIT satellite meeting before the IS-MPMI meeting, July 2019, Glasgow. |
| Collaborator Contribution | Colleague engaged and exchanged information on Xylella outbreaks in Italy with BRIGIT consortium members, and contributed samples of (potential) insect vectors for genome sequencing to the BRIGIT project. |
| Impact | We will generate sequence data that can be used for development of diagnostics tools of (potential) Xylella insect vectors. |
| Start Year | 2019 |
| Description | Collaboration with Liverpool School of Tropical Medicine (LSTM) |
| Organisation | Liverpool School of Tropical Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Write iCASE studentship in collaboration with colleagues at LSTM and Syngenta. The proposal made it through the DTP process of the Norwich Research Park. We identified a suitable candidate who accepted the position. |
| Collaborator Contribution | Contributed to the writing of the iCASE studentship. |
| Impact | An iCASE studentship that starts Oct '20 |
| Start Year | 2019 |
| Description | Collaboration with Syngenta on an iCASE studentship |
| Organisation | Syngenta International AG |
| Department | Syngenta Ltd (Bracknell) |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Wrote iCASE studentship. Advertised position for PhD student and hosted and interviewed applicant. |
| Collaborator Contribution | Contributed to the writing of the iCASE studentship |
| Impact | iCASE project that starts Oct '20. |
| Start Year | 2019 |
| Description | Collaboration with University of Kyoto |
| Organisation | University of Kyoto |
| Country | Japan |
| Sector | Academic/University |
| PI Contribution | Collaborator is involved in a research project of a PhD student in the lab |
| Collaborator Contribution | Collaborator provided transgenic plant lines for screening |
| Impact | Progress made with research goals of PhD student project |
| Start Year | 2018 |
| Description | Collaboration with University of Lisbon, Portugal |
| Organisation | University of Lisbon |
| Country | Portugal |
| Sector | Academic/University |
| PI Contribution | I involved colleagues at University of Lisbon in the BRIGIT project and the sequencing of genomes and transcriptomes of insect vectors of Xylella fastidiosa. I invited colleague to give lecture and exchange knowledge with BRIGIT consortium members at consortium meeting in Edinburgh, July 2019, and at the BRIGIT satellite meeting before the IS-MPMI in Glasgow, July 2019. We co-authored on a publication. |
| Collaborator Contribution | Partners collected insects in Portugal and send these to us for sequencing. Partners engaged with BRIGIT consortium members. |
| Impact | Generated new knowledge on population structures of X. fastidiosa insect vectors. Co-published the genome sequence of the spittle bug Philaenus spumarius as a dataset in Zenodo (DOI:10.5281/zenodo.3368385) and agreed to sequence more European Philaenus species that are potential vectors of Xylella. |
| Start Year | 2018 |
| Description | Collaboration with University of Oxford |
| Organisation | University of Oxford |
| Department | Department of Plant Sciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Visited colleagues at University of Oxford to discuss specific project and experimental approaches |
| Collaborator Contribution | Contributed knowledge and resources for new experiments |
| Impact | Progress with achieving research goals by graduate student and postdoctoral researcher in the lab. Making plans for a collaborative research proposal. |
| Start Year | 2019 |
| Description | Collaboration with University of Stellenbosch |
| Organisation | University of Stellenbosch |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | We will sequence and annotate the genome of one clone of Diuraphis noxia, a serious pest of wheat in South Africa and many other countries worldwide |
| Collaborator Contribution | Contributed frozen materials for D. noxio aphids |
| Impact | We generated a genome assembly of D. noxia. |
| Start Year | 2016 |
| Description | Collaboration with plant breeding company on an iCASE studentship |
| Organisation | Sesvanderhave |
| Country | Belgium |
| Sector | Private |
| PI Contribution | PhD student in the laboratory is generating aphid genome sequence data and population structure analyses. Student is enrolled in supervisory system at JIC and engages with experienced researchers in the lab and at JIC. |
| Collaborator Contribution | Provides staff and resources for conducting the study and involved student in research project at the company for 3 months. |
| Impact | PhD student made excellent progress with his research and generated data useful for the host lab at JIC and the industrial partner. |
| Start Year | 2016 |
| Description | Collaboration with sugar beet seed breeding company |
| Organisation | Sesvanderhave |
| Country | Belgium |
| Sector | Private |
| PI Contribution | Expertise on sap-sucking insect pests, such as aphids and leafhoppers, and molecular plant-insect interactions, insect genomics, the Arabidopsis thaliana model system and translation of knowledge obtained from a model plant to a crop. Writing of projects to obatin research funding. |
| Collaborator Contribution | Sugar beet germplasm collections and genome sequence data an expertise in sugar beet genetics and breeding strategies. |
| Impact | Outputs and outcomes are confidential. Two patents were filed. |
| Start Year | 2017 |
| Description | Collaborations with The Sainsbury Laboratory |
| Organisation | John Innes Centre |
| Department | The Sainsbury Laboratory |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Provide knowledge on the aphid-plant interactions experimental system. |
| Collaborator Contribution | Colleagues at The Sainsnury Laboratory have contributed knowledge and expertise to a PhD student project in my lab. |
| Impact | The PhD student made good progress with achieving research goals of his PhD project. |
| Start Year | 2017 |
| Description | Engaged with German Centre for Integrative Biodiversity Research (iDIV) |
| Organisation | German Centre for Integrative Biodiversity Research |
| Country | Germany |
| Sector | Charity/Non Profit |
| PI Contribution | Enabled PhD student at the German Centre for Integrative Biodiversity Research (iDiv) to be engaged with our GCRF-funded project to study Napier grass stunt phytoplasma |
| Collaborator Contribution | Collected Napier grass with phytoplasma symptoms and potential insect vectors from fields near small farmers village |
| Impact | Materials are being processed for sequencing |
| Start Year | 2018 |
| Description | Engaged with colleagues at the International Centre of Insect Physiology and Ecology (ICIPE) |
| Organisation | International Centre of Insect Physiology and Ecology (ICIPE) |
| Country | Kenya |
| Sector | Academic/University |
| PI Contribution | Involved colleague at ICIPE in the GCRF-funded project to study Napier grass stunt phytoplasma |
| Collaborator Contribution | Provided plant and insect materials for sequencing |
| Impact | Materials are being processed |
| Start Year | 2018 |
| Description | Formal collaboration with BecA, Nairobi, Kenya |
| Organisation | International Livestock Research Institute (ILRI) |
| Country | Kenya |
| Sector | Charity/Non Profit |
| PI Contribution | We provide information on phytoplasma effectors and how they interact with plant targets. This will help the identification of resistance in Napier grass and other crops susceptible to phytoplasmas. |
| Collaborator Contribution | The BecA team provided information on Napier grass germ plasm and genomics resources that will be mined for phytoplasma effector targets and polymorphisms in these targets that lead to insusceptibility to phytoplasma effectors. |
| Impact | Two members of the Hogenhout group (a research assistant and PhD student) have visited BecA and ICIPE for several days. They joined a symposium and presented talks about their researcj in this symposium. They exchanged knowledge and resources. |
| Start Year | 2017 |
| Description | Formal collaboration with CGIAR |
| Organisation | CGIAR |
| Country | France |
| Sector | Charity/Non Profit |
| PI Contribution | We sequence the genome and transcriptome of the banana aphid, an economically important pest of banana in Africa, Asia and Australia |
| Collaborator Contribution | Provided frozen aphids for genome and transcriptome sequencing |
| Impact | Provided the full genome sequence to the collaborator |
| Start Year | 2017 |
| Description | Formal collaboration with Fera, UK |
| Organisation | Fera Science Limited |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | I involved colleauges at Fera in the BRIGIT project |
| Collaborator Contribution | FERA colleagues lead Work Package 2 (WP2) of the BRIGIT project. The main goal of WP2 is to optimize and improve technologies for diagnostics of Xylella fastidiosa in diverse plant species, including trees. Another FERA colleague is involved in WP3 of the BRIGIT project. The main goal of WP3 is to better understand the migration patterns of X. fastidiosa insect vectors in the UK. FERA colleagues are involved in the social sciences aspect of WP4 of the BRIGIT project. The main goal of WP4 is to model the potential pathways of spread of X. fastidiosa in the UK. |
| Impact | Protocol optimization for diagnostics of Xylella fastidiosa has started. |
| Start Year | 2018 |
| Description | Formal collaboration with Forest Research, England and Scotland |
| Organisation | Forest Research |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Involved colleagues at Forest Research in the BRIGIT project |
| Collaborator Contribution | Collaborator 1 at Forest Research leads Work Package 1 (WP1) of the BRIGIT project. The main aims of WP1 are to develop activities to involved citizen scientists and stakeholders in the BRIGIT project and develop databases with information on various aspects of Xylella fastifiosa and its insect vectors. Collaborator 2 at Forest Research is involved in WP2 of the BRIGIT project. WP2 is focused on developing diagnostics for X. fastidiosa and is lead by colleagues at Fera. Collaborator 3 at Forest Research is involved in developing the social sciences aspect of WP4 of the BRIGIT project. |
| Impact | Planning of citizen scientist and stakeholder activities have started. |
| Start Year | 2018 |
| Description | Formal collaboration with Natural Environment Research Council |
| Organisation | UK Centre for Ecology & Hydrology |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Involved Natural Environment Research Council colleague in the BRIGIT project |
| Collaborator Contribution | 1. Leads Work Package 4 of the BRIGIT project; 2. Models the potential pathways of spread of Xylella fastidiosa in the UK |
| Impact | Started to collate data from project partners to do the modelling and interacts with scientists in Europe to help develop the model. |
| Start Year | 2018 |
| Description | Formal collaboration with Royal Horticultural Society |
| Organisation | Royal Horticultural Society |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Involved the Royal Horticultural Society in the BRIGIT project. |
| Collaborator Contribution | Colleagues at Royal Horticultural Society developed a database of plant species susceptible to Xylella fastidiosa. |
| Impact | Dr. Gerard Clover has been hired as the Engagement Officer for the BRIGIT project and works 4 days per week at the JIC |
| Start Year | 2018 |
| Description | Formal collaboration with Science and Advice for Scottish Agriculture |
| Organisation | Science and Advice for Scottish Agriculture |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | I involved colleagues at SASA in the BRIGIT project |
| Collaborator Contribution | Colleagues at SASA are involved in Work Package (WP) 2 and 3 of the BRIGIT project. WP2 is aimed at optimizing and further developing technologies for diagnostics of Xylella fastidiosa within BRIGIT, and WP3 is aimed at better understanding the migration of X. fastidiosa insect vectors in the UK. |
| Impact | Work on WP2 and WP3 have started |
| Start Year | 2018 |
| Description | Formal collaboration with University of East Anglia |
| Organisation | University of East Anglia |
| Department | School of Biological Sciences UEA |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Member of the supervisory committee of a PhD student in the TC lab (iCASE studentship with Oxitec). |
| Collaborator Contribution | Colleague is member of supervisory committee of my PhD student (iCASE studentship with Oxitec). |
| Impact | Gained new insights on how to control insect pests of plants. |
| Start Year | 2015 |
| Description | Formal collaboration with University of East Anglia |
| Organisation | University of East Anglia |
| Department | School of Economics |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Involved the colleague in the BRIGIT project |
| Collaborator Contribution | Colleague contributes towards accomplishing goals in WP4 of the BRIGIT project |
| Impact | WP4 of BRIGIT is making good progress |
| Start Year | 2019 |
| Description | Formal collaboration with University of Salford |
| Organisation | University of Salford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Involved colleague in the BRIGIT project. |
| Collaborator Contribution | Colleague participates in Work Package (WP4) of the BRIGIT project. WP4 is modelling the potential pathways of spread of Xylella fastidiosa in the UK. |
| Impact | Collation of data for the modelling of WP4 has started. |
| Start Year | 2018 |
| Description | Formal collaboration with University of St Andrews |
| Organisation | University of St Andrews |
| Department | Department of Geography & Sustainable Development |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I involved colleague at University of St Andrews in the BRIGIT project |
| Collaborator Contribution | Dr Rehema White contributes to teh goals of WP4 in the BRIGIT project. |
| Impact | Work on WP4 has been going as planned. |
| Start Year | 2019 |
| Description | Formal collaboration with University of Stirling |
| Organisation | University of Stirling |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Involved colleague in the BRIGIT project. |
| Collaborator Contribution | Colleague participates in Work Package 4 (WP4) of the BRIGIT project. The aim of WP4 is to model the potential pathways of spread of Xylella fastidiosa in the UK. |
| Impact | Collating data for starting the modelling of WP4 of BRIGIT has started. |
| Start Year | 2018 |
| Description | Formal collaboration with University of Sussex |
| Organisation | University of Sussex |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I involved collaboratort in the BRIGIT project |
| Collaborator Contribution | Collaborator contributes Entomology expertise to the BRIGIT project |
| Impact | 1. Funding of the BRIGIT project by UKRI Strategy Priority Fund. 2. Access to UK database of amateur and professional entomologists to collect candidate insect vector species of Xylella fastidiosa. |
| Start Year | 2018 |
| Description | Formal research collaboration with Academia Sinica, Taipei, Taiwan |
| Organisation | Academia Sinica |
| Department | Institute of Plant and Microbial Biology |
| Country | Taiwan, Province of China |
| Sector | Academic/University |
| PI Contribution | Development of the research question, approaches and methodology. Provided knowledge about the biology of the organisms, collected biological material, extracted DNA and generated raw reads of genome sequence data. Invited groupe leader at Academia Sinica to the BRIGIT consortium meeting of July 2019 in Edinburgh. |
| Collaborator Contribution | Assembled the genome reads into contigs and annotated the genomes. Contributed a talk and exchanged knowlede on Xylella comparative genome analyses with WP2 members of the BRIGIT consortium at the BRIGIT consortium meeting of July 2019 in Edinburgh. Contributed a talk at the BRIGIT satellite meeting before the IS-MPMI meeting of July 2019, Glasgow. |
| Impact | Several co-authored publications. Exchanged information on Xylella genome sequence comparisons that is useful for developing diagnostics protocols in WP2 of the BRIGIT project. |
| Start Year | 2014 |
| Description | Formal research collaboration with Chinese Academy of Agricultural Sciences (CAAS), Beijing, China |
| Organisation | Chinese Academy of Agricultural Sciences |
| Country | China |
| Sector | Academic/University |
| PI Contribution | My group provides aphid genomics information to the project. |
| Collaborator Contribution | CAAS contributed aphid samples and transgenic wheat to achieve plant-mediated RNAi of aphids to the project |
| Impact | We sequenced the genomes of many wheat-colonizing aphid species. The genomes have been assembled. Annotation pipeline for the genomes is under construction. |
| Start Year | 2016 |
| Description | Formal research collaboration with Earlham Institute, Norwich, UK |
| Organisation | Earlham Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Our time provides knowledge, resources and materials for the insect-plant interaction research system. |
| Collaborator Contribution | Colleagues team provides knowledge on bioinformatics and genomics, including genome and transcriptome assembly pipelines and genome annotations. |
| Impact | We obtained two BBSRC-IPA collaborative grants with Syngenta. We co-supervise postdoctoral researchers and PhD students. We are co-authors on Mathers et al., 2017. Genome Biology, and a paper that is being submitted this month. We assisted postdoctoral researcher Thomas Mathers with the writing of a Future leader fellowship application, which was succesful (starts Apr 2018). |
| Start Year | 2010 |
| Description | Formal research collaboration with Institute of Plant Protection, Poznan, Poland |
| Organisation | Institute of Plant Protection, National Research Institute |
| Country | Poland |
| Sector | Public |
| PI Contribution | My lab hosted a PhD student of the Institute of Plant Protection at JIC, Oct 2016 - Mar 2017. The student conducted work on the HFSP collaborative project. |
| Collaborator Contribution | The team in Poznan collects plant and insect samples in northern and southern regions of Poland for the HFSP project; the samples were assayed for the presence of phytoplasma strains and effector genes. |
| Impact | We wrote a HFSP project proposal together that was funded. We hold regular Skype meetings (in average, once in the 6 weeks) to discuss progress and results. |
| Start Year | 2014 |
| Description | Formal research collaboration with SESVanderHave |
| Organisation | Sesvanderhave |
| Country | Belgium |
| Sector | Private |
| PI Contribution | My research group has provided advise on strategies to obtain aphid resistant sugar beet, exchanged knowledge on research progress in plant-insect interactions of the lab, and wrote BBRSC-LINK award to fund research. |
| Collaborator Contribution | SESVanderHave provides access to sugar beet breeding lines, genome sequence resources for these lines and insecticide-free field sites for collection of aphid populations in UK and Europe. They also funded a postdoctoral researcher in my group for one year, contributed 50% in-kind funds for the BBSRC-LINK award and funds a iCASE studentship in my group. PhD student Roland Wouters was recruited for the iCASE project. Roland is making good progress. |
| Impact | Generated knowledge on plant-insect interactions. Organized visits of the SESVanderHave team to JIC (two times per year) and my group at JIC to SESVanderHave headquarters in Tienen, Belgium (two times per year). Organized regular Skype calls to discuss research progress and ideas for future research. |
| Start Year | 2013 |
| Description | Formal research collaboration with SIPPE, CAS, Shanghai, China |
| Organisation | Chinese Academy of Sciences |
| Department | Shanghai Institute of Plant Physiology and Ecology |
| Country | China |
| Sector | Academic/University |
| PI Contribution | My group provides knowledge, resources and materials, and (genome/gene) sequence information of various species of aphids. |
| Collaborator Contribution | Huang's group provides information on insect transformation methods, insect sex determination genes, baculovirus and insect cell-based expression systems. |
| Impact | We excnahed visits and attended (CEPAMS) meetings to discuss research progress. Qun Liu, Yazhou Chen and Weijie Huang, former postdoctoral researchers and PhD students at SIPPE, are currently postdoctoral researchers in the Hogenhout group. |
| Start Year | 2014 |
| Description | Formal research collaboration with Sultan Qaboos University, Muscat, Oman. |
| Organisation | Sultan Qaboos University |
| Department | Department of Crop Sciences |
| Country | Oman |
| Sector | Academic/University |
| PI Contribution | Provided intellectual input into investigating an important pathogen of lime trees in Oman, and hosted PhD student of Sultan Qaboos University at JIC for 6 months in 2015/2016 and 3 months in 2017. |
| Collaborator Contribution | Provided funding for research conducted by the visiting PhD student and hosted me to visit phytoplasma-infected lime orchards and vegetable farms in Oman. |
| Impact | Co-authored scientific publications. |
| Start Year | 2014 |
| Description | Formal research collaboration with Syngenta |
| Organisation | Syngenta International AG |
| Department | Syngenta Ltd (Bracknell) |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Provide information about aphid biology and genomics, and mechanisms involved in aphid adjustment to diverse plant species and pesticides. |
| Collaborator Contribution | Contributed 10% cash towards two BBSRC-IPA projects (2014-2017; 2017-2020) and advised on how to conduct pesticide applications. Provided aphid clones for sequencing and analyses. |
| Impact | Made progress with understanding processes involved in aphid adjustments to plants and pesticides. This collaboration resulted in a publication: Mathers, Chen et al., 2017. Genome Biol. 18: 27. As well, the collaboration was renewed with follow-up funding, that is a BBSRC-IPA grant commencing April 2018. Held regular meetings to discuss progress, including visits of my group to Syngenta and collagues of Syngenta to JIC, and Skype and phone conference meetings. |
| Start Year | 2014 |
| Description | Formal research collaboration with University of East Anglia, Norwich, UK |
| Organisation | University of East Anglia |
| Department | School of Environmental Sciences UEA |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Knowledge, resources and materials for the insect-plant interaction research system. |
| Collaborator Contribution | Colleague's team provides knowledge on evolutionary biology and population genetics. |
| Impact | We obtained two BBSRC-IPA collaborative grants with Syngenta. We co-supervise postdoctoral researchers and PhD students. We co-authored on publications. We assisted postdoctoral researchers with the writing of a succesful Future Leader Fellowship application. |
| Start Year | 2013 |
| Description | Formal research collaboration with University of Sao Paolo - College of Agriculture (ESALQ) |
| Organisation | Universidade de São Paulo |
| Department | College of Agriculture |
| Country | Brazil |
| Sector | Academic/University |
| PI Contribution | Provided intellectual input into development of a collaborative research proposal, expertise in specific research methodologies and trained staff in molecular biology methods. Members of the partner team visited my team to gain experience with molecular biology techniques and discuss project progress. These included: - Visit of ESALQ group leader to Hogenhout lab, 11-18 Sep. 2013. - Visit of ESALQ group leader to Hogenhout lab, 20-24 Oct. 2014. - Visit of ESALQ postdoctoral researcher to Hogenhout lab, March - Dec, 2014. |
| Collaborator Contribution | Provided intellectual input into development of a collaborative research proposal, expertise in specific research methodologies and trained and hosted staff for conducting field-based experiments. Members of my team visited the partner lab for field trips. These included: - Field trip and processing of samples in Brazil of a PhD student in my team, 18 May - 8 June, 2013. - Visit of Hogenhout to partner lab, 28-31 Oct, 2013. - Field trip and processing of samples in Brazil, 6-21 June, 2014. - Visit and processing of samples in Brazil, 19-23 Oct, 2015. |
| Impact | Co-authored several publications. |
| Start Year | 2013 |
| Description | Formal research collaboration with University of Wisconsin, Madison, USA |
| Organisation | University of Wisconsin-Madison |
| Department | Department of Entomology |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | We involved the University of Wisconsin team into a HFSP research proposal that got funded. |
| Collaborator Contribution | The University of Wisconsin team collects phytoplasma-infected plant and leafhopper samples from all over the USA for the HFSP-funded project. |
| Impact | We received funding for collaborative HFSP project. We hold regular progress meeting (in average once/6 weeks). We co-supervise postdoctoral researchers and PhD students. We are writing up a manuscript. |
| Start Year | 2014 |
| Description | Formal research collaboration with University of Zagreb, Croatia |
| Organisation | University of Zagreb |
| Department | Department of Molecular Biology |
| Country | Croatia |
| Sector | Academic/University |
| PI Contribution | Provided expertise on genome-wide analyses and identification and functional characterization of effectors of phytoplasmas. Hosted members of the Croatia team several times and helped the team to obtain a research grant in Croatia. |
| Collaborator Contribution | The Croatia team provided useful sequence information to my team and contributed to the writing of publications. |
| Impact | Exchanged useful data and co-published scientific publications. Another publication is in preparation and will be submitted in March 2018. |
| Start Year | 2010 |
| Description | Formal research collaboration with Wageningen University and Research Centre, The Netherlands |
| Organisation | Wageningen University & Research |
| Department | Department of Plant Sciences |
| Country | New Zealand |
| Sector | Academic/University |
| PI Contribution | We provided knowledge on phytoplasma virulence proteins that interfere with plant development and involved the Wageningen team into a interdisciplinary project proposal that received funding from HFSP. |
| Collaborator Contribution | The Wageningen team provided expertise on plant transcription factors targeted by phytoplasma effectors and helped us with interpretation of the plant developmental phenotypes. They are co-investigators on our HFSP grant. |
| Impact | We received funding for a HFSP research project. We co-published a paper: MacLean et al., 2014. PLoS Biol. 12(4):e1001835. We co-supervise postdoctoral researchers. We hold regular Skype meetings (in average once per 6 months) for the past 3 years. |
| Start Year | 2014 |
| Description | Partnership award with University of Liverpool, UK. |
| Organisation | University of Liverpool |
| Department | School of Veterinary Science Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provide information on vector-borne diseases of plants. |
| Collaborator Contribution | Provide information of vector-borne diseases of humans and animals. |
| Impact | We won a US Partnering Award: Vector-borne diseases in the UK & US: common threats and shared solutions" and co-organized visits of US colleagues to the UK (Dec 2016) and UK group members to the University of California, Davis (Oct 2017). We applied for a GCRF VBD network grant together; the pre-proposal for this was selected for submission of a full proposal, and we were invited for an interview with BBSRC based on our full proposal submission. The proposal was ranked 5th out 12 proposals, and only the top 3 were funded. Finally, we co-organized the Vector-Borne Diseases in the UK meetings, 3-4 Dec 2018 hosted at the JIC. |
| Start Year | 2016 |
| Description | Partnership with Defra |
| Organisation | Department For Environment, Food And Rural Affairs (DEFRA) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | I engaged with Defra colleagues and upper management to develop the BRIGIT proposal. We are currently working on response policies in the event Xylella fastidiosa is detected in the UK and strategies for integration of outcomes of the BRIGIT project in these reponse policies. |
| Collaborator Contribution | Contribution of a wide range of knowledge on policy making and (methods for) collection of data for the BRIGIT project. |
| Impact | We have weekly meetings when Dr. Sutton-Croft is at the John Innes Centre at one day per week. |
| Start Year | 2018 |
| Title | Annotation of genes encoding long non-coding RNAs in aphid genomes |
| Description | We developed a pipeline to annotate genes for long non-coding RNAs in aphid genomes |
| Type Of Technology | Software |
| Year Produced | 2018 |
| Impact | We have the sequences of aphid candidate long non-coding RNAs |
| Title | Improve aphid genome assembly pipeline |
| Description | We optimized methods to improve aphid genome assemblies using existing software |
| Type Of Technology | Software |
| Year Produced | 2018 |
| Impact | We obtained high quality chomosome level assemblies of aphid genomes |
| Title | Improved aphid genome annotation pipeline |
| Description | We work with the Earlham Institute to optimize annotation of aphid genomes |
| Type Of Technology | Software |
| Year Produced | 2019 |
| Impact | Improved annotation of aphid genomes. |
| Description | AMM at APS, Minneapolis, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A postdoc presented an invited talk in teh session Interconnected lifecycles: multitrophic interactions between plants, pathogens and insects at the American Phytopathological Society (APS) - Canadian Phytopathological Society Joint Meeting, Minneapolis, USA, 9-13 August 2014. The talk sparked questions and discussion afterwards. |
| Year(s) Of Engagement Activity | 2014 |
| Description | APS, Tampa, FL, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a research talk about my lab's recent progress made in functional analyses of phytoplasma effector proteins and how they change plant development and plant susceptibility to insect pests at the American Plant Pathology Society meeting, Tampa, Florida. |
| Year(s) Of Engagement Activity | 2016 |
| Description | AgroSight |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Hosted and discussed potential research project on phytoplasma pathogens of oil palms in Columbia with Mayke Santos, AgroSIght, Cambridge, UK. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Annual Symposium Lausanne, Switserland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a seminar in the Annual Symposium Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland, 7 Nov 2014. This sparked questions and discussion afterwards. I engaged with leading and young scientists to discuss research. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Attended Annual conference of the Italian Society for Crop Genetics |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attended scientific conference 'Science and innovation for sustainable agriculture intensification: the contribution of plant genetics and breeding' of the Italian Society for Crop Genetics, presented invited lecture and engaged with colleagues. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Attended Australasian Plant Pathology Society (APPS) meeting, Melbourne, Australia |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attended and presented at the annual Australasian Plant Pathology Society meeting. Met with colleagues who work on approaches to prevent Xylella from spreading in Australia and New Zealand and neighbouring countries. Established international contacts for the BRIGIT project. Exchanged knowledge about a wide range of (invasive) insect-transmitted plant pathogens that cause threats to agriculture worldwide. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.apps2019.org/ |
| Description | Attended Gatsby Plant Science Annual Meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Attended the annual meeting on behalf of Gatsby-funded graduate student |
| Year(s) Of Engagement Activity | 2019 |
| Description | Attended Introductory programme for UvA professors |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Study participants or study members |
| Results and Impact | Participated in an introductory programme for UvA professors. The Executive Board of the University of Amsterdam offers this programme to all newly appointed UvA professors, to facilitate them in their new role in the academic community and as UvA representatives. The programme offered insights and tools that helped strengthen personal effectiveness in daily work situations including extending network within the UvA. It also allows to gain more insight into the role and position of a UvA professor, meet colleagues and exchange experiences plus learn more about Dutch academic leadership codes. Furthermore, organizational and financial aspects of the university will be highlighted as well as current developments within the UvA and the role of academic leadership. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Attended meeting at Bill and Melinda Gates foundation |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | Attended a meeting and presented a poster at the Grand Challenges; Explorations Agricultural Development (Round 8 & 9) and Nutrition (Round 7 & 8) Convening, Bill and Melinda Gates foundation, Seattle, Washington, USA, May 2013. Engaged with African scientists and assessed if the technology produced in this project is useful for applications to protect crops from whitefly pests and research of colleagues. |
| Year(s) Of Engagement Activity | 2013 |
| Description | BBRO |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Discussed opportunities for collaboration with BBRO with Mark Stevens (Centrum Building, NRP, Norwich, UK). |
| Year(s) Of Engagement Activity | 2017 |
| Description | BSCD and BSDB |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a research talk about my lab's recent progress made in functional analyses of phytoplasma effector proteins and how they change plant development and plant susceptibility to insect pests. |
| Year(s) Of Engagement Activity | 2016 |
| Description | BecA |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | GCRF project discussions with Sita Ghimire (BecA, Nairobi, Kenya) |
| Year(s) Of Engagement Activity | 2017 |
| Description | Biotechnology conference, Cuba |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a talk in a parallel session at the Biotechnology Conference, Havana, Cuba, 1-5 Dec 2014. This sparked questions and discussion afterwards. |
| Year(s) Of Engagement Activity | 2014 |
| Description | CONNECTED |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attended and participated in network discussions of CONNECTED UK Launch conference, Bristol, UK (hosted by Gary Foster, Neil Boonham and Nicola Spence), 29-31 Jan '18. |
| Year(s) Of Engagement Activity | 2018 |
| Description | COST meeting, Copenhagen, Denmark |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I have a talk at the Plant-Insect-Microbe Interactions Symposium, Copenhagen, Denmark, 16 April 2015. This sparked questions and discussion afterwards. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Chair of Insectary Platform Steering Committee |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chair of committee that ensures that the JIC Insectary/Entomology Technology Platform is well managed, proactive, effective, state of the art and resourced to meet the Institutes' science needs. |
| Year(s) Of Engagement Activity | 2017,2018,2019 |
| Description | Chair of Technical Platform Oversight Committee (TPOC) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chair the committee that ensures that all JIC Technology Platforms are collectively well managed, proactive, effective, state of the art and resourced to meet the Institutes' science needs. |
| Year(s) Of Engagement Activity | 2017,2018,2019 |
| Description | Chair of the Library and Information Services Steering Group, JIC |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Make decisions on Library and Information Services at JIC. |
| Year(s) Of Engagement Activity | 2013,2014,2015,2016,2017,2018,2019 |
| Description | Chaired session at IPMB, Iguassu Falls, Argentina |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Organized and chaired a parallel session on plant-insect interactions at the International Plant Molecular Biology 2015 meeting, Iguassu Falls, Argentina - Brazil, 25-30 October 2015. Established contacts with leaders in the field and engaged with students and postdoctoral researchers. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Co-chaired session at MPMI meeting, Rhodes, Greece |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Co-chaired concurrent session Neglected Systems at the International Congress of Molecular Plant-Microbe Interactions (MPMI), Rhodes, Greece, 6-10 July 2014. I established contacts with leaders in the MPMI field and engaged with students and postdoctoral scientists. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Co-chaired session at SEB, Manchester, UK |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I organized a co-chaired the session Mechanisms of Plant-Insect Interactions at the Society of Experimental Biology (SEB) meeting, Manchester, UK, 1-5 July 2014. I invited colleagues who are leaders in the field of Plant-Insect Interactions from academic institutions worldwide to present talks in this session. A student and a postdoc in my team presented talks as well and engaged with the international speakers and the audience. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Communication of research findings via Natural History magazine |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | MacLean et al. (2014). PLoS Biol. 12: e1001835 was featured in Natural History magazine (published in the United States; mission: to promote public understanding and appreciation of nature and science). |
| Year(s) Of Engagement Activity | 2014 |
| Description | Communication of research findings via The Economist |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | MacLean et al. (2014). PLoS Biol. 12: e1001835 was featured in the Science and Technology section of the print edition of The Economist: 'Symbiosis and parasitism: The sorceress's apprentice'. (12 April 2014). |
| Year(s) Of Engagement Activity | 2014 |
| Description | Communication of research findings via international newspapers |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | MacLean et al. (2014). PLoS Biol. 12: e1001835 was highlighted in on-line national media of China (China today), Japan, Russia, USA, Vietnam, Indonesia, Greece, Italy, Spain, France, Germany, The Netherlands (Scientias; Nieuws.nl; Quest; Acksmedia) and UK (Daily Mail; EDP24). |
| Year(s) Of Engagement Activity | 2014 |
| Description | Communication of research findings via local newspapers |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | MacLean et al. (2014). PLoS Biol. 12: e1001835 was featured in printed editions of the Eastern Daily Press (9 April 2014) and Evening News (9 April 2014): 'The zombie invasion really is coming'. These articles were advertised on billboards 'Norwich zombie plants riddle' in front of news agencies in Norwich. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Communication of research findings via radio |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | We contributed to Radio: NTR de Kennis van nu, radio 5, The Netherlands (Podcast April 30 2014 by Richard Immink); Moment of Science, Indiana Public Media, USA (broadcasted 2nd week of May 2014). |
| Year(s) Of Engagement Activity | 2014 |
| Description | Communication of research findings via various websites and on-line media |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | MacLean et al. (2014). PLoS Biol. 12: e1001835 was highlighted on various websites of international media: Nature News; Scientific American; New York Times; Hortidaily (online meeting place for the international horticulture industry) with 2-min video of JIC; Students Science (Society of Science); Science 2.0; Science, Space & Robots; I fucking love science; Otters and Science News; Fearnet; Engadget. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Communication of research findings via video and press release |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | We produced a 2-minute video at John Innes Centre (Chris Wilson) to communicate research of MacLean et al. (2014). PLoS Biol. 12: e1001835 to a general audience - released 8 April 2014 along with written press releases of John Innes Centre (Zoe Dunford) and Wageningen University and Research Centre (Erik Toussaint). |
| Year(s) Of Engagement Activity | 2014 |
| Description | Contributed an 'Accessible Science Talk' for the Research and Support Staff Voice (RSSV) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | The JIC Research and Support Staff Voice (RSSV) organised a day (9 Oct 2018) of talks as part of the JIC Annual Science Meeting, delivered by top scientists from JIC and TSL. Every talk was accessible to a wide audience including scientists, support and partnership staff and communicates the great work carried out at JIC and TSL, presented in a manner that will be understandable and interesting for all. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Contributed to a press release |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Contributed to a press release to announce funding of this project from Bill and Melinda Gates Foundation Grand Challenges Explorations Program (2013). |
| Year(s) Of Engagement Activity | 2013 |
| Description | Contribution of two lectures for BIO-3C20 Molecular Plant-Microbe Interactions course |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | Postdoctoral researcher Adi Kliot in my lab will contribute two lectures in the BIO-3C20 Molecular Plant-Microbe Interactions, Spring Semester, University of East Anglia, March 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | EPS, Soest |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I presented a talk at the Dutch Graduate School Experimental Plant Sciences (EPS), Soest, The Netherlands (invited by PhD students), 29-30 Jan 2015. The audience was predominantly postgraduate students. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Engaged with journalists from Africa |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Engagement with the general public: Presented talk for group of African journalists visiting the JIC, Apr. 2014 |
| Year(s) Of Engagement Activity | 2014 |
| Description | Engagement with BBSRC as part of the BRIGIT project |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Have weekly meetings with policy makers at BBSRC about new policies that may be developed to reduce the risk of Xylella fastidiosa outbreaks in the UK |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Engagement with Defra, Forest Research and APHA as part of the BRIGIT project |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Have weekly meetings with policy makers at Defra about new policies that may be developed to reduce the risk of Xylella fastidiosa outbreaks in the UK |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Engagement with Fera as part of the BRIGIT project |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Have weekly meetings with Fera about status of Xylella fastidiosa diagnostics that may influence new policies for reducing risk of X. fastidiosa outbreaks in the UK |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Engagement with Oxitec |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Regular meetings with Neil Morrison for supervisory meetings and discussing research progress of the iCASE studentship. |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018,2019 |
| Description | Engagement with SV |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Three-monthly meetings with industrial collaborators |
| Year(s) Of Engagement Activity | 2017,2018,2019 |
| Description | Engagement with Syngenta |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Regular meetings with colleagues at Syngenta, Jealott's Hill, UK, and Switserland and USA to discuss project proposals and research progress on aphids. |
| Year(s) Of Engagement Activity | 2010,2011,2012,2013,2014,2015,2016,2017,2018,2019 |
| Description | Engagement with the Royal Horticulticultural Society as part of the BRIGIT project |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Third sector organisations |
| Results and Impact | Have weekly meetings with staff member of RHS to develop a stakeholder engagement plan for BRIGIT |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Frequent meetings with Oxitec |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | We meet four times with colleagues at Oxitex for the supervisory meeting of the PhD student. The student contributes a presentation with the latest progress on the project. We exchange knowledge. |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018,2019 |
| Description | GMI, Vienna |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a research talk about my lab's recent progress made in functional analyses of phytoplasma effector proteins and how they change plant development and plant susceptibility to insect pests at the Gregor Mendel Institute, Vienna, Austria. |
| Year(s) Of Engagement Activity | 2016 |
| Description | HFSP meeting, SIngapore |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Presented a research talk about my lab's recent progress made in functional analyses of phytoplasma effector proteins and how they change plant development and plant susceptibility to insect pests at the Human Frontier Science Program (HFSP) meeting, Singapore. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Hosted Alexander Stacey, BSc student Biological Sciences, University of East Anglia, UK. |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | Student worked on a research project in the summer of 2018 and his BSc research project from Jan-Mar '19. |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Hosted Alexandra Kolodyazhnaya, BSc student Novosibirsk State University, Russia |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Undergraduate students |
| Results and Impact | Student did a research project in my lab as part of the JIC/TSL/EI International Undergraduate Summer School programme at JIC. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Hosted Libby Hanwell, BSc student Biological Sciences, University of East Anglia, UK |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | Hosted the student for a research project in the summer of 2018 and her BSc research project from Oct-Dec '18 |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Hosted Luke Sherwin, MSc student Molecular Medicine at the University of East Anglia, UK. |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | MSc project for BIO_6019Y course. Luke wrote a 3000-word project and did a research project Mar-Sep 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Hosting of Milind Sood, BSc student, University of Oxford, UK. |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Undergraduate students |
| Results and Impact | Will do a research project in my lab as part of the JIC/TSL/EI International Undergraduate Summer School programme at JIC, Jun-Aug 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | ICE, Florida, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented an invited talk at the International Conference of Entomology (ICE), Orlando, Florida, USA. |
| Year(s) Of Engagement Activity | 2016 |
| Description | IMPRS, Jena |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Presented a keynote lecture at the 16th IMPRS Symposium (organized by PhD students at Max Planck Institute), Donburg Castle, Jena, Germany. |
| Year(s) Of Engagement Activity | 2017 |
| Description | IS-MPMI organizing committee |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Local organizing committee for IS-MPMI 2019, Glasgow, UK. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited research seminar at 'When Development meets Stress' symposium, CRAG, Barcelona, Spain |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a talk on Phytoplasma at the 'When Development meets Stress' symposium, Center for Research in Agricultural Genomics (CRAG), Barcelona, Spain, 2-4 Sep 2018. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.bdebate.org/en/forum/when-development-meets-stress-understanding-developmental-reprogram... |
| Description | Invited research seminar at CAS institute |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a research seminar at IGDB, Beijing, China on 16 Mar 2018. Research fellow Thomas Mathers in my lab also contributed a talk. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited research seminar at iDiv, Leipzig, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited by PhD students to give a research presentation at the Integrative Biodiversity Research Institute (iDiv), Halle-Jena-Leipzig, Germany, 18 Apr 2018. I was hosted by Crispus Mbaluto, PhD student at iDiv. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited research seminar at the Max Planck Institute, Cologne, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to give a research seminar at the Max Planck Institute for Plant Breeding, Cologne, Germany. Approximately 50 people, including PhD students, attended. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited research seminar at the XI European Congress of Entomology, Naples, Italy |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a research seminar on Phytoplasma in a parallel session focused on insect-transmitted plant pathogens and plant-insect interactions. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited research seminar at the annual Life Sciences conference, Beijing, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a talk in a paralell session focused on insect pests at the Life Sciences Conference, Beijing, China, 28-31 Oct '19. |
| Year(s) Of Engagement Activity | 2018 |
| Description | MCC at SEB, Manchester, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A visiting postdoc in the lab presented a talk in the parallel session Mechanisms of Plant-Insect Interactions at the Society of Experimental Biology (SEB) meeting, Manchester, UK, 1-5 July 2014 |
| Year(s) Of Engagement Activity | 2014 |
| Description | Marburg, Germany |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented an invited talk at the Frontiers in Microbiology Symposium, Max Planck Institute, Marburg, Germany. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Meeting with Norwich Institute for Sustainable Development |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Study participants or study members |
| Results and Impact | We exchanged information and research interest with colleagues at the Norwich Institute for Sustainable Development, University of East Anglia, UK to assess posisbilities for future collaborations. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Member Scientific Resources Committee |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Member of a committee that decides on purchases of all types of scientific equipment and organization of JIC infrastructure. |
| Year(s) Of Engagement Activity | 2017,2018,2019 |
| Description | Member of Programme Management Group of JIC Next Generation Infrastructure |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Feb 2018 - current Member of Programme Management Group of JIC Next Generation Infrastructure |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Member of Tenure-Track faculty mentoring committee |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Provide advise to young faculty |
| Year(s) Of Engagement Activity | 2016,2017,2018,2019 |
| Description | Member of supervisory committee of PhD student at University of Wisconsin, Madison, USA |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Aug 2018 - current: Member of supervisory committee of PhD student Shannon Piper, University of Madison, Wisconsin, USA. |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Member of the JIC Distribution of Exploitation Income (DEI) Panel |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Helped to decide on the Distribution of Exploitation Income of colleages at the Norwich Research Park |
| Year(s) Of Engagement Activity | 2012,2013,2014,2015,2016,2017,2018,2019 |
| Description | OARDC, Wooster, OH, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I presented a talk at my former workplace: The Ohio State University - Ohio Agriculture and Development Center (OARDC), Wooster, Ohio, USA. 10-13 May 2015. This sparked questions and discussions afterwards. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Organization of BRIGIT activities at the BSPP 'Our Plants, Our Future' meeting, Royal Society, London |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Frequently communicated with upper management of Defra to organize BRIGIT event at the 'Our Plants, Our Future' meeting, Royal Society, London. Invited plenary speaker from Brazil to talk about Xylella fastidiosa problem in citrus and practical solutions. Organized BRIGIT poster session presented by ± 20 BRIGIT consortium members. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.bspp.org.uk/conferences/our-plants-our-future/ |
| Description | Organized BRIGIT satellite meeting 'Dynamics and Mechanism of Insect-Transmitted Pathogens' at IS-MPMI conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This satellite meeting brought together scientists with an interest in studying the diverse aspects of insect-transmitted plant pathogen interactions with their plant hosts and insect vectors. These pathogens cause the most destructive diseases of plants and are often responsible for eradication of entire crop industries in countries or regions. Current examples include Olive Quick Decline Syndrome (Xylella fastidiosa), citrus greening (Candidatus Liberibacter sp.), Lime Witch's Broom and Grapevine Flavescence doree (Candidatus Phytoplasma) and Cassava mosaic (geminivirus). The meeting covered (1) Recognition and induction of immunity, (2) Effectors and modulation of insect/plant processes, (3) Epidemiology and insect transmission and (4) Genomics and Evolution. There were 8 invited talks from international scientists and 5 short talks selected from abstracts. BRIGIT consortium members attended the satellite meeting and engaged with the speakers. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.ismpmi.org/Congress/2019/program/Pages/Satellite-Meetings.aspx |
| Description | Organized and hosted a conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Member of organizing committee and host of Vector-Borne Disease in the UK 2018, JIC, Norwich, UK, 3-4 Dec 2018. |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Organized first BRIGIT consortium meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Organized first BRIGIT consortium meeting, London, 6 Feb, 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Organized second BRIGIT consortium meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Organized the second BRIGIT consortium meeting at SASA, Edinburgh, 12 July, 2019. Researchers with expertise in research on Xylella fastidiosa and its insect vectors and plant hosts from California, Italy, Taiwan and Portugal attend this meeting and exchanged knowledge with consortium members. The meeting was attended by policy makers and plant inspectors. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Organizing the satellite meeting 'Dynamics and Mechanism of Insect-Transmitted Pathogens' at the IS-MPMI |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This satellite meeting will be organized on Sunday 14th July, 8.30 - 15.00, and brings together scientists with an interest in studying the diverse aspects of insect-transmitted plant pathogen interactions with their plant hosts and insect vectors. These pathogens cause the most destructive diseases of plants and are often responsible for eradication of entire crop industries in countries or regions. Current examples include Olive Quick Decline Syndrome (Xylella fastidiosa), citrus greening (Candidatus Liberibacter sp.), Lime Witch's Broom and Grapevine Flavescence doree (Candidatus Phytoplasma) and Cassava mosaic (geminivirus). The meeting will cover (1) Recognition and induction of immunity, (2) Effectors and modulation of insect/plant processes, (3) Epidemiology and insect transmission and (4) Genomics and Evolution. If you would like to attend or contribute to the meeting, please contact Saskia Hogenhout, Silke Robatzek, Sheng-Yang He and Steven Lindow by 15 April 2019 at the very latest. |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.ismpmi.org/Congress/2019/program/Pages/Satellite-Meetings.aspx |
| Description | Participated in conference at Syngenta |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Attended Syngenta external collaboration event. Three postdoctoral lab members in my group presented research talks and updates with their project progress. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Participated in visit of Syngenta to the Norwich Research Park |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Discussed progress on current funded projects and possibilities of future projects with colleagues from Syngenta. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Participated summerschool, Pwani University, Kenya |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Co-organized a two-day course as part of the two-week AfriPlantSci summerschool for ±25 professionals and students from research institutes and university in Kenya and several other countries in sub-saharan Africa. Two PhD students of my team participated in the organization of the summerschool. Protocols we taught in the course were shared and are being used in current projects of the course participants. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Participation in autumn workshop of The Sainsbury Laboratory |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Participated in the autumn workshop of The Sainsbury Laboratory. A PhD student in my group gave a talk and received substantial feedback. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Phillipines |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Communicated and wrote proposal for the Newton Afgham Programme with Karen Alviar, National Institute of Molecular Biology (BIOTECH), University of the Philippines, Los Banos. The objective was to investigate effector proteins of the cassava phytoplasma disease (CPD), which has caused massive outbreaks in the Philippines. Unfortunately, the application was considered to have eligibility problems for unclear reasons. An appeal letter was submitted (Jun 2017), but this did not help. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Phytopathological Society, Colmar, France |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I presented a talk at the French Phytopathology Meeting, Colmar, France, 2-5 June 2015. This sparked questions and discussion afterwards. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Phytopathology conference, Brazil |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | SH presented a talk at the 46th Meeting of the Brazilian Phytopathological Society/11th Brazilian Meeting on Biological Control, Ouro Preto, Brazil, 20-25 October 2013. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Presented a talk at Monogram |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a talk at Monogram, JIC, Norwich, UK, 24-16 Apr 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Presented a talk at a whitefly conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a talk (invited based on abstract submission) at the 1st International Whitefly Symposium, Kolymbari, Sicily, Italy, May 2013. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Presented talk at JIC "Science for Innovation Showcase" event |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Presented a talk at the JIC "Science for Innovation Showcase" event, Norwich, UK, 7-8 Feb '18. I explored opportunities to collaborate with industry. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Press release to announce BRIGIT project |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Engaged with JIC Public Engagement Officer to launch press release 'UK consortium to combat serious threat to plant health' to announce the start of the BRIGIT project and the BRIGIT project website |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.jic.ac.uk/press-release/uk-wide-consortium-to-combat-serious-threat-to-plant-health/ |
| Description | Press release to announce new appointment for the BRIGIT project |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Engaged with JIC Public Engagement Officer to launch press release 'New appointment for UK-wide Xylella pathogen consortium' for the BRIGIT project |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.jic.ac.uk/news/new-appointment-for-uk-wide-xylella-pathogen-consortium/ |
| Description | Progress meeting with industrial collaborator |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Regular progress meetings with colleagues SESVanderHave to discuss project made with BBSRC-LINK and iCASE projects. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Summerschool, Utrecht |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Presented a talk and engaed with students at the 9th Utrecht PhD Summerschool Environmental Signaling in Plants, Utrecht, The Netherlands, 28-30 Aug 2017 |
| Year(s) Of Engagement Activity | 2017 |
| Description | UK Microbiology Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a research talk about my lab's recent progress made in functional analyses of phytoplasma effector proteins and how they change plant development and plant susceptibility to insect pests. |
| Year(s) Of Engagement Activity | 2016 |
| Description | UK-US VBD network |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | UK-US Vector-borne disease network meeting, University of California, Davis, 15-17 Oct 2017. Co-organized UK-US VBD network meeting with Matthew Baylis (University of Liverpool, UK) at the University of California, Davis, USA. |
| Year(s) Of Engagement Activity | 2017 |
| Description | VBD, Liverpool |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented a research talk about my lab's recent progress made in aphid-plant interactions research at the UK Vector-Borne Diseases meeting. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Visit of Syngenta |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Visited Syngenta to give update on project progress. Three team members presented and engaged with Syngenta colleagues. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Visited University of Lisbon and went for field trip in Portugal |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Visited University of Lisbon to discuss collaboration for BRIGIT project, met with colleagues from research institutes and industry to dicuss Xylella fastidiosa spread in the UK, presented lectures in insect-vectored pathogen and visited ecological farm in Portugal. |
| Year(s) Of Engagement Activity | 2019 |