An open consortium for molecular understanding of ash dieback disease

Lead Research Organisation: John Innes Centre
Department Name: Contracts Office

Abstract

Ash dieback caused by Hymenoscyphus pseudoalbidus (anamorph Chalara fraxinea, Cf) is now widespread in UK ash (Fraxinus excelsior L.). The Nornex consortium of eleven research centres coordinated at JIC aims to understand the genomes of the fungus, its host and the pathogenic interaction.

Understanding the genome and pathogenic nature of the fungus H. pseudoalbidus. The aims of the fungal genomics are (1) to understand the genome diversity of the pathogen in Europe, (2) to determine if there is any structure to this population (3) to identify relationships to indigenous Hymenoscyphus species, (4) to try to identify the potential origin of the pathogen. The aims of the pathogenesis studies are (5) to set up tests of infection and tests of pathogenicity in vitro and in the field, (6) to assess antibodies for diagnostic tests (7) to understand the survival of the fungus and factors that affect its spread (8) to identify fungal genes induced during plant infection and those genes that contribute to the pathogenic nature of the pathogen.
Identifying genetic tolerance in ash. The aims are to (a) generate genome sequence and genetic map of ash and (b) map disease tolerance. DNA sequencing of a tree with low susceptibility is in progress and mapping will be done with progeny from a cross with this and another single tree. Mapping of disease tolerance will be done using a transcriptome-based approach. Expressed genes will be identified by RNA sequencing and genetic mapping will be done by sequencing RNA from of a diversity panel of trees with varying susceptibility to the pathogen. These data will be used to identify genes whose expression levels show a significant association with disease tolerance and DNA polymorphisms in genes that show association with inheritance of low susceptibility. Further details of the project and partners can be found at http://nornex.org/ and updates on research outputs are posted at http://oadb.tsl.ac.uk/ .

Publications

10 25 50
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Langner T (2018) CRISPR Crops: Plant Genome Editing Toward Disease Resistance. in Annual review of phytopathology

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Maclean D (2013) Changing the rules of the game. in eLife

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Edwards A (2016) A plague on our ashes in Microbiology Today

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MacLean D (2014) Out of the woods. Ash dieback and the future of emergent pathogenomics. in Molecular plant pathology

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Michelmore R (2017) Foundational and Translational Research Opportunities to Improve Plant Health. in Molecular plant-microbe interactions : MPMI

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Edwards A (2018) Rapid progression of ash dieback disease in an ancient wood in the UK in Quarterly Journal of Forestry

 
Title A biologist's poem 
Description This 'real and singular thing'. A piece of code in its own genome. A copy from the past, multipliable, repeatable, yet mutable. You couldn't help feeling that you had stolen this sequence from its owner. You had transferred a piece of life into the human consciousness. with apologies to Wim Wenders /w @SaskiaHogenhout 
Type Of Art Creative Writing 
Year Produced 2018 
Impact Positive feedback on social media 
URL http://kamounlab.tumblr.com/post/170774045435/a-biologists-poem
 
Title I Will Survive (biotroph remix) 
Description A plant pathology inspired song. I Will Survive (biotroph remix) [with apologies to Gloria Gaynor] Oh, no, not I I will survive Oh, as long as I know how to infect you I'll stay alive I've got all my life to live I've got all my spores to give And I'll survive I will survive, hey, hey 
Type Of Art Creative Writing 
Year Produced 2018 
Impact >15K impressions on social media and ~250 engagements 
URL https://twitter.com/KamounLab/status/1098214166723215361
 
Description Nature of the fungal pathogen Hymenoscyphus fraxineus (Chalara fraxinea):
(a) Genomics
We set out to establish a reference genome sequence of the pathogen and to use this to analyse the diversity, phylogenetic relatedness of H. fraxineus to other fungi and possible source of the infection.
The genomes (DNA) of many pathogen isolates were analysed and compared with isolates from Japan. This revealed European strains to be a small subset, probably reflecting a founder effect.
This means Europe should aim to limit further ingress, in case new isolates introduce greater genetic diversity that might overcome existing resistance.
(b) Pathology
At the outset of this programme there were no reproducible in vitro tests of pathogenicity in tree seedlings or means of following infection by the pathogen. We aimed to develop this using transgenic pathogen and/or targeted monoclonal antibodies. The former was unsuccessful, but useful monoclonal antibodies were produced and these were usefully deployed.
• We have shown that (asexual) conidiospores are infective and we propose an extended model for the lifestyle of the pathogen involving infection via roots and leaves.
• Different isolates of the pathogen have differential levels of pathogenicity. This means that tests of tree susceptibility must be done with multiple isolates.
• We can now generate in vitro, infective sexual spores of defined parentage.
• Trees with low susceptibility have distinctive secondary metabolites. This was an additional aim. This indicates a secondary diagnostic tool for identification and selection of disease tolerance.
Identifying genetic resistance in Ash trees: (a) Genomics
To map genetic loci associated with disease tolerance, we required genome sequence of ash. This was done both within Nornex and in collaboration with Queen Mary University London.
• Excellent genome assemblies have been produced from trees with low disease susceptibility. These complement the analysis (from Queen Mary University London) on the British ash tree genome.
• Genome sequences from a further 37 diverse ash genotypes have been obtained.
(b) Genetic mapping by Associative Transcriptomics
We proposed using a novel RNA-sequenced based approach to map disease tolerance. This proved to be very successful.
• We have identified genetic markers that strongly predict inheritance of disease tolerance both in Danish and UK ash trees. This provides the information required to build a population of trees with low disease susceptibility and thereby rebuild the ash population.
Exploitation Route We have identified genetic markers that strongly predict inheritance of disease tolerance both in Danish and UK ash trees. This provides the information required to build a population of trees with low disease susceptibility and thereby rebuild the ash population.
Different isolates of the pathogen have differential levels of pathogenicity. This means that tests of tree susceptibility must be done with multiple isolates.
Sectors Agriculture, Food and Drink,Communities and Social Services/Policy,Education,Environment

URL http://nornex.org/
 
Description An aim of the programme was that the data generated by Nornex should be open access and that we should engage both the public and non-Nornex scientists in the research. This required setting up a website, which successfully facilitated access to data and open engagement • The OADB website http://oadb.tsl.ac.uk/ provided rapid access to data (especially to genomics and transcriptomics) and enabled others to analyse the data. This helped recruit and build new collaborations with others. • The Fraxinus game harnessed and channelled public interest, providing useful genome analyses. It also gave insights into how such games can be used to harness public engagement in other studies.
First Year Of Impact 2013
Sector Agriculture, Food and Drink,Education,Environment
Impact Types Societal,Economic

 
Description Advisory Committee Chair, International Congress of Plant Pathology (ICPP18) in Boston, MA
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact ICPP 2018 adopted the theme "Plant Health is Earth's Wealth" for ISPP 2013-2018 recognising that plant pathogens don't just threaten food security and well-being. They also affect, forest and fibre systems, natural ecosystems, biodiversity and environmental harmony, and impede trade and market access. And, phytopathology research has also been a central focus for discovery and development in biotechnology and plant-microbial molecular biology. For our profession - people are the pivotal element, and while in the coming years, the ISPP will maintain a focus on plant disease impacts on food security, it should and will also foster attention to all facets of our profession through our Congresses, subject matter committees and our website, newsletter and Journal. In this light, the ISPP taskforce on global food security which has more than achieved it objectives will now become a Commission working in the same way as other ISPP Subject Matter Committees. https://www.isppweb.org/newsletters/pdf/48_8.pdf One of the major outcomes was the proposal for a code of ethics for plant health emergencies: * to foster ethical conduct * to support communication and collaboration * to ensure that decisions are based on the best available evidence See https://www.isppweb.org/newsletters/pdf/48_12.pdf
URL https://www.isppweb.org/newsletters/pdf/48_8.pdf
 
Description CABANA External Advisory Committee
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact What is CABANA? CABANA is a capacity strengthening project for bioinformatics in Latin America. It aims to accelerate the implementation of data-driven biology in the region by creating a sustainable capacity-building programme focusing on three challenge areas - communicable disease, sustainable food production and protection of biodiversity. CABANA is orchestrated by an international consortium of ten organisations - nine in Latin America and one in the UK. CABANA is funded by the Global Challenges Research Fund (GCRF) - part of the UK Aid Budget - from October 2017 to December 2021.
URL http://www.cabana.online
 
Description Comment on Court of Justice of the European Union (CJEU) ruling-Organisms obtained by mutagenesis are GMOs and are, in principle, subject to the obligations laid down by the GMO Directive
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
Impact This ruling ignores advances in plant bioediting that make this technology more precise than so-called "conventional mutagenesis". Bioediting can be also be used to recapitulate natural variations into cultivated varieties of crops. This ruling closes the door to many beneficial genetic modifications such as breeding of disease resistant plants that require much less pesticide input. A sad day for European plant science. Disseminated via Science Media centre and social media.
URL http://kamounlab.tumblr.com/post/176262512395/comment-on-court-of-justice-of-the-european-union
 
Description Global preparedness for emerging diseases
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact To build resilience against unintentional spread of crop disease threats, we present the argument for a global surveillance system (GSS) for de-risk global food supplies and increase resilience to crop diseases. The model for the GSS draws on lessons learned from established national and regional plant protection organizations and on measures implemented in more developed countries. The GSS would extend these agricultural biosecurity measures into LDCs, enhancing overall global food protection. The conference on "Building resilience against crop diseases: A global surveillance system" is supported by the Rockefeller Foundation and will be held Feb. 12-16, 2018, at The Bellagio Center in Lake Como, Italy. Simone Staiger, Head of Knowledge Management and Learning at CIAT, is facilitating the meeting.
URL http://kamounlab.dreamhosters.com/storify/RFBellagio_storify.html
 
Description Gregor Mendel Institute of Molecular Plant Biology Science Advisory Board
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact The GMI is part of the Vienna BioCenter (VBC), one of the leading international biomedical research centers worldwide that has established itself as the premier location for life sciences in Central Europe.
URL https://www.oeaw.ac.at/gmi/
 
Description Inst. Plant and Microbial Biology (IPMB), Academia Sinica, Taiwan, Science Advisory Board.
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Academia Sinica is Taiwan's premier government-supported academic research institution, with 31 institutes and centers representing a wide range of disciplines in the sciences and humanities. It is located in the Nankang district, on the outskirts of metropolitan Taipei. One of the Life Sciences Institutes, The Institute of Plant and Microbial Biology (IPMB) has 26 fellows (professor equivalents) whose research follows one of two central themes: the mechanisms of plant functioning or plant-microbial interactions. Some 300 support staff consisting of specialists, postdoctoral fellows, graduate students, Research Assistant and administrative personnel work under the research fellows. IPMB has modern infrastructure and equipment. An active education program is also set up, with Ph.D. students from the Taiwan International Graduate Program, Academia Sinica, or from their adjunct programs with National Taiwan University and National Central University. IPMB research fellows have previously made landmark discoveries in such areas as rice breeding and genomics, regeneration via tissue culture, virus satellite RNA, microbial circadian rhythm, etc. For a long time goal, we aim to improve the quality and quantity of research performance and achieve visibility in international scientific community. Over the past decade, IPMB has undergone a major reorganization and rejuvenation, and has added a number of outstanding junior fellows.
 
Description Journals 2.0: a roadmap to reinvent scientific publishing
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Promoted preprints and open science and a different, more sustainable, form of scientific publishing therefore accelerating the dissemination of science and reducing the exorbitant costs of scientific publishing. This vision describes a radically different publishing model that would reinvent the concept of a scientific journal into a live and open forum of scientific debate and analysis. This model centers on a full integration of the preprint ecosystem into the journal interface. The journal would only accept submission of articles that have been posted as preprints. All evaluations and commissioned reviews of submitted articles would be published as soon as received on the journal website and linked to the preprint version. Editors would operate as always sifting through submitted papers and seeking external reviewers when necessary. But they will also consider author-led and community crowdsourced reviews, which would be appended to the preprint. As the reviews accumulate and revisions are submitted, the journal editors would initiate a consultation process, and when satisfied with a given version promote it to a formal article. The editor's role becomes more akin to moderator than gatekeeper. The process doesn't have to be static. As the community further comments on the article and follow-up studies are published, editors may decide to commission synthetic review or commentary articles to address emerging issues. I would also envision that the paper is linked to related articles in a "knowledge network" database, and that article tags are revised to reflect new knowledge, e.g. "independently validated". The journal would therefore become less of a static repository of scientific articles, and more of a moderated forum of scientific discussion.
URL https://zenodo.org/record/1466784#.XH2SPi2cawQ
 
Description Point of view: wither pre-publication peer review to reinvent scientific publishing
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Promoted open science and preprints among the research community therefore resulting in more rapid dissemination of scientific findings.
URL http://kamounlab.tumblr.com/post/178573217080/point-of-view-wither-pre-publication-peer-review
 
Description Establishment of JENNIFER population of ash genotypes 
Organisation East Malling Research
Country United Kingdom 
Sector Academic/University 
PI Contribution Production of replicated clones of 328 Fraxinus accessions in the JENNIFER collection, for future research on ash including ash dieback, resistance to herbivores and phenological traits.
Collaborator Contribution East Malling: Cloning the Fraxinus accessions by grafting. Norfolk CC and Forest Research: Provision of trial sites with deer fence for ash dieback trials.
Impact Planted field trial near Acle, Norfolk, January 2018.
Start Year 2015
 
Description Establishment of JENNIFER population of ash genotypes 
Organisation Forest Research
Country United Kingdom 
Sector Public 
PI Contribution Production of replicated clones of 328 Fraxinus accessions in the JENNIFER collection, for future research on ash including ash dieback, resistance to herbivores and phenological traits.
Collaborator Contribution East Malling: Cloning the Fraxinus accessions by grafting. Norfolk CC and Forest Research: Provision of trial sites with deer fence for ash dieback trials.
Impact Planted field trial near Acle, Norfolk, January 2018.
Start Year 2015
 
Description Establishment of JENNIFER population of ash genotypes 
Organisation Norfolk County Council
Country United Kingdom 
Sector Public 
PI Contribution Production of replicated clones of 328 Fraxinus accessions in the JENNIFER collection, for future research on ash including ash dieback, resistance to herbivores and phenological traits.
Collaborator Contribution East Malling: Cloning the Fraxinus accessions by grafting. Norfolk CC and Forest Research: Provision of trial sites with deer fence for ash dieback trials.
Impact Planted field trial near Acle, Norfolk, January 2018.
Start Year 2015
 
Description NORNEX Buggs 
Organisation Queen Mary University of London
Department School of Biological and Chemical Science QMUL
Country United Kingdom 
Sector Academic/University 
PI Contribution We were involved in DNA (genome) sequencing of several ash trees selected by Dr Buggs.
Collaborator Contribution Dr Buggs group generated and annotated the genome of a UK ash tree of low genetic complexity and the resulting data were used to predict gene models that could be used in RNA sequence analyses (Associative Transcriptomcs) that led to the identification of genetic markers predicting trees which have low susceptibility to ash dieback disease
Impact PMID: 28024298 PMID: 26757823
Start Year 2013
 
Description Nornex: Kjaer 
Organisation University of Copenhagen
Department Department of Geosciences and Natural Resource Management
Country Denmark 
Sector Academic/University 
PI Contribution We used their selected ash trees for DNA and RNA sequencing, ultimately identifying genetic markers that could be used to screen for ash trees with low susceptibility to ash dieback disease
Collaborator Contribution They generated a panel of grafted ash trees using scions for grafts selected with a high proportion of trees showing low disease symptoms. They isolated DNA and RNA from leaves of those trees and sent it to our partners for sequencing and analysis. They routinely scored the trees for disease progression enabling genetic markers from the sequencing to be correlated with low susceptibility. They routinely gave advice and help with regard to scoring disease and with handling the fungal pathogen
Impact PMID: 28024298 PMID: 26757823
Start Year 2013
 
Title Ash Dieback Crowdsource Data Repository 
Description The actual data structure 'back-end' holding crowdsource and genomics data for the OADB hub project/ 
Type Of Technology Webtool/Application 
Year Produced 2013 
Impact Data generated outside the Nornex project were contributed and used by many researchers and in the first year the following genomics outputs of the ash dieback pathogen had been achieved: the community generated a first-pass genome assembly containing abundant collapsed AT-rich repeats indicating a typically complex genome structure. Twelve assembled transcriptomes of H.pseudoalbidus from the UK and two from Japan. Annotations of the pathogen genome. Assessment of genetic diversity of the H.pseudoalbidus population in the UK 
URL https://github.com/ash-dieback-crowdsource
 
Title Fraxinus Facebook Crowdsourcing Application 
Description Flash based crowdsourcing game to allow members of the public to analyse genetic data related to ash dieback 
Type Of Technology Webtool/Application 
Year Produced 2013 
Impact Approximately 60,000 people played this game and contributed effort towards the identification of polymorphisms in our genetic data. 
URL https://www.facebook.com/fraxinusgame/
 
Title OADB Crowdsource Hub 
Description OADB is the public source of data and reports of the crowdsourced analysis open access results of studies on ash and ash dieback. 
Type Of Technology Webtool/Application 
Year Produced 2013 
Impact Data generated outside the Nornex project were contributed and used by many researchers and in the first year the following genomics outputs of the ash dieback pathogen had been achieved: the community generated a first-pass genome assembly containing abundant collapsed AT-rich repeats indicating a typically complex genome structure. Twelve assembled transcriptomes of H.pseudoalbidus from the UK and two from Japan. Annotations of the pathogen genome. Assessment of genetic diversity of the H.pseudoalbidus population in the UK 
URL http://oadb.tsl.ac.uk
 
Title OADB GeeFu site 
Description An instance of the GeeFu web application for browsing and manual curation of genomics data 
Type Of Technology Webtool/Application 
Year Produced 2014 
Impact Shared the genomics data of the Nornex and crowdsourcing projects in an easily accessible fashion to bench biologists. 
URL https://geefu.oadb.tsl.ac.uk/
 
Description 'Betty' the ash tree offers hope against deadly dieback disease: The Guardian-22 Apr 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described the identification of UK ash trees with predicted low susceptibility to ash dieback and low observed disease susceptibility
Year(s) Of Engagement Activity 2016
URL https://www.theguardian.com/environment/2016/apr/22/betty-the-ash-tree-offers-hope-against-deadly-di...
 
Description 'Crowd-sourcing' could speed ash dieback breakthroughs; Norwich Evening News-8 Mar 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Described how the public could help analyse genome sequence data on ash dieback by playing the compute game Fraxinus
Year(s) Of Engagement Activity 2013
URL http://www.eveningnews24.co.uk/news/crowd_sourcing_could_speed_ash_dieback_breakthroughs_at_norwich_...
 
Description Advisor, Nornex 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Prof James Brown was one of the two advisors to the Nornex project on ash dieback, contributing knowledge about population genetics and plant breeding.
Year(s) Of Engagement Activity 2013,2014,2015,2016
 
Description Anglia TV March 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interviews with Anglia TV about BBSRC?DEFRA funding award to deal with ash dieback disease
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/03/major-cash-for-ash/
 
Description Ash dieback breakthrough as scientists learn to spot resistant trees Telegraph.co.uk-13 Jan 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Explained how we could use genetic markers to identify trees with low susceptibility to ash dieback disease
Year(s) Of Engagement Activity 2016
URL http://www.telegraph.co.uk/news/earth/environment/12098065/Ash-dieback-breakthrough-as-scientists-le...
 
Description Ash dieback disease inspires artistic response from Wymondham high school students; Norfolk Eastern Daily Press-10 Jul 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact This documented a school visit that was aimed at engaging school students in understanding ash dieback disease and producing art related to it
Year(s) Of Engagement Activity 2013
URL http://www.edp24.co.uk/news/environment/ash_dieback_disease_inspires_artistic_response_from_wymondha...
 
Description Ash dieback is feared to be even more devastating than we had feared: Daily Mail-28 Oct 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact This explained published work that showed that the ash dieback fungus had a second mode of infection via asexual conidiospores.
Year(s) Of Engagement Activity 2016
URL http://www.dailymail.co.uk/news/article-3884142/Ash-dieback-feared-devastating-thought-95-trees-kill...
 
Description Ash dieback screening could leave trees defenceless against beetles: Telegraph.co.uk-26 Dec 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described the potential trade off that having genes for ash dieback resistance may change metabolites causing sensitivity to insect attack
Year(s) Of Engagement Activity 2016
URL http://www.telegraph.co.uk/science/2016/12/26/ash-dieback-screening-could-leave-trees-defenceless-ag...
 
Description Ash trees have 'fighting chance' against deadly disease ITV news Dec 2016 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Interview on ash tree genome sequence and how improved genetic markers increase prediction and identification of ash trees with low disease susceptibility
Year(s) Of Engagement Activity 2016
URL http://www.itv.com/news/anglia/update/2016-12-28/ash-trees-have-fighting-chance-against-deadly-disea...
 
Description Ashes to Ashes BBC Radio 4 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Ashes to Ashes documentary describing the progress of ash dieback disease in the UK and the spread of the disease via fruiting bodies and their spores. Also involved Dr Richard Buggs and genome sequence of UK ash.
Year(s) Of Engagement Activity 2013
URL http://www.bbc.co.uk/programmes/b03bg4vh
 
Description BBC Countryfile 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact BBC Countryfile in depth analysis of progression of ash dieback in the UK, identification of fungal genome sequences and the first released ash tree genome sequence via the open-access scientific approach we were taking into research on ash dieback disease
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/06/genome-sequence-for-mother-of-ash-dieback-survival/
 
Description BBC Farming Today June 2014 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Description of progression of ash dieback disease, progress on BBSRC/DEFRA-funded research and potential for selection of ash trees with low susceptibility
Year(s) Of Engagement Activity 2014
URL http://www.bbc.co.uk/programmes/b047z8wq
 
Description BBC Inside Out Aug 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Interview for documentary on BBC Inside Out programme, explaining ash dieback disease, how to identify it, how widespread it was, what caused it and what research steps were being taken to deal with it. This included explaining how genome sequencing could be used and how the public could help with analyses of sequence reads by playing the computer game 'Fraxinus'.
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/08/gamers-to-join-ash-dieback-fight-back/
 
Description BBC Look East March 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interview about BBSRC/DEFRA funding to NORNEX partners for research into ash dieback. Resulted in contacts with pubic and other scientists
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/03/major-cash-for-ash/
 
Description BBC Newsnight April 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Describe to the public the novel (crowdsourcing) way we were approaching research into ash dieback
Year(s) Of Engagement Activity 2013
 
Description BBC Radio 4 'Today' interview Aug 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact BBC radio 4 interview for 'Today' programme. Explaining progress of ash dieback disease, how genome sequencing could help and how citizen science could contribute via computer game Fraxinus
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/08/gamers-to-join-ash-dieback-fight-back/
 
Description BBC Radio Humberside interview 3/1/17 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Live interview on progress in Ash Dieback Research. BBC Radio Humberside Drivetime News 3/1/17
Year(s) Of Engagement Activity 2017
 
Description BBC TV news Aug 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact BBC TV news interview describing progression of ash dieback in the UK and how BBSRC/DEFRA-funded research was being used to understand the genomes of the ash tree and the ash dieback pathogen. It also described the 'Fraxinus' game that engaged the public in helping analyse DNA sequences from that research.
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/08/gamers-to-join-ash-dieback-fight-back/
 
Description BBC Today (Edwards) Oct 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Progression of ash dieback one year on and the start of looking for markers associated with ash trees of low susceptibility
Year(s) Of Engagement Activity 2013
URL http://www.bbc.co.uk/news/science-environment-24675356
 
Description BBC breakfast news 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact BBC TV interview describing ash dieback disease, the first draft of the genome sequence of the pathogen and what we hoped to achieve scientifically with the BBSRC/DEFRA research funding to work on ash dieback
Year(s) Of Engagement Activity 2013
URL http://www.bbc.co.uk/news/science-environment-21433466
 
Description BBC on Betty the resistant ash 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described the identification using genetic markers of a tree (called Betty) predicted to have low susceptibility to ash dieback disease and also found to have very low disease symptoms despite being in an area of heavy infection
Year(s) Of Engagement Activity 2016
URL http://www.bbc.co.uk/news/uk-england-norfolk-36110639
 
Description BBC radio 4 Today 27th Dec 2016 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Describe the impact of sequencing the ash genome and how that could be used to try to deal with ash dieback; also discussed the dangers of Emerald Ash borer
Year(s) Of Engagement Activity 2016
 
Description BBC-LOOK East_Anne Edwards BEM 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Anne Edwards was interviewed in relation to the British Empire Medal she had been awarded. In the interview she described the work she had been involved with in relation to the identification of ash dieback in the wild and the BBSRC/DEFRA research aimed at trying to deal with the consequences of the disease
Year(s) Of Engagement Activity 2015
 
Description BBSRC Website 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact BBSRC-produced film for BBSRC website explaining ash dieback disease and the scientific approach being taken to deal with it
Year(s) Of Engagement Activity 2013
URL http://www.bbsrc.ac.uk/news/videos/2013/1309-v-how-i-discovered-ash-dieback-transcript/
 
Description BBSRC video relating to ash dieback research 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact BBSRC video relating to ash dieback research
Year(s) Of Engagement Activity 2016
URL https://www.youtube.com/watch?v=kA39bpXRd08
 
Description Britain's Ash forests face extinction - but a tree named Betty: The Conversation UK-26 Apr 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Described how genetic markers could be used to identify ash trees with low ash dieback disease susceptibility
Year(s) Of Engagement Activity 2016
URL http://theconversation.com/britains-ash-forests-face-extinction-but-a-tree-named-betty-could-save-th...
 
Description British ash trees may resist dieback disease, research reveals; The Guardian-26 Dec 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described how genome-based markers indicate that more UK trees than expected may have ash dieback disease tolerance
Year(s) Of Engagement Activity 2016
URL https://www.theguardian.com/environment/2016/dec/26/british-ash-trees-may-resist-dieback-disease-res...
 
Description Conference poster: PAG XVII 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Poster presentation at the Plant and Animal Genomes conference in San Diego. This was done to bring my research to a wider audience.
Year(s) Of Engagement Activity 2019
 
Description Costing the Earth BBC March 2014 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Description of spread of ash dieback disease and dangers from other pests.
Year(s) Of Engagement Activity 2014
URL http://www.bbc.co.uk/programmes/b03xf0gc#play
 
Description Could 'Betty' save our forests? In-Depth-Daily Mail-22 Apr 2016... 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described with the example of the tree 'Betty' how genomic markers could be used to identify ash trees with low susceptibility to the ash dieback fungus.
Year(s) Of Engagement Activity 2016
URL http://www.dailymail.co.uk/sciencetech/article-3553630/Could-Betty-save-forests-Genes-tree-reveal-im...
 
Description CropLife FoodHeroes Series: What inspires plant scientists and why is their job so important? 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Why did you want to be a plant scientist?

I became a scientist because I grew up being extremely curious about the natural world. I wanted to know how living organisms function. How they became the way they are. Plant pathology came later after realized that I may as well study a field of biology that is important to the human condition. This inspires me to narrow the gap between fundamental and applied research. My aim is to perform cutting-edge research and significantly advance knowledge on economically important plant pathogen systems. In contrast, much research focuses on model systems and is therefore further steps away from practical applications.

Can you explain what your job involves?

As an academic scientist, I am in the business of knowledge. My job is to generate new knowledge to advance science, and to influence others to pursue new directions, generate more knowledge and apply it to address practical problems. My job is also to communicate scientific knowledge and discoveries to my peers and to a broader audience, including the general public.

What are the plant diseases that you are working on?

I work primarily on blight and blast diseases. Throughout my career, I have worked primarily on the Irish potato famine pathogen Phytophthora infestans. More recently, I was inspired by the sense of urgency brought upon by the February 2016 Bangladeshi wheat blast epidemic to expand my research to blast fungi. I aim to apply the concepts and ideas I developed throughout my career to a problem with an immediate impact on global food security.

Can you describe how damaging these diseases can be for farmers?

Plant diseases are a major constraint for achieving food security. Losses caused by fungal plant pathogens alone account for enough to feed several billion people. Magnaporthe oryzae, the causal agent of blast disease of cereals, is among the most destructive plant pathogens, causing losses in rice production that, if mitigated, could feed up to 740 million people. This pathogen has emerged since the 1980s as an important pathogen of wheat seriously limiting the potential for wheat production in South America. In 2016, wheat blast was detected for the first time in Asia with reports of a severe epidemic in Bangladesh. The outbreak is particularly worrisome because wheat blast has already spread further to India, and is threatening major wheat producing areas in neighboring South Asian countries. Global trade and a warming climate are contributing to the spread and establishment of blast diseases as a global problem for cereal production and a present and clear danger to food security.

Why is your profession important in the challenge to feed the world?

Plant pathology delivers science-driven solutions to plant diseases. In particular, genetic solutions through disease resistant crop varieties can be sustainable and environmentally friendly.

What inspires you about your job?

Knowledge and people. The thrill of learning something new every day is addictive. Sharing the experience with others -be they students, colleagues, stakeholders or members of the public - is priceless.
Year(s) Of Engagement Activity 2017
URL https://croplife.org/industry-profile/sophien-kamoun/
 
Description Crowdsourcing approach 2012 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Launching our crowdsourcing approach to investigating the pathogen causing ash dieback
Year(s) Of Engagement Activity 2012
URL https://www.jic.ac.uk/news/2012/12/crowdsourcing-to-kickstart-comeback-from-ash-dieback/
 
Description DNA clue could help beat dieback plague killing Britain's ash trees; Daily Mail-16 Jun 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described first release to open access site of genome sequence data from a Danish ash tree with low susceptibility to ash dieback disease
Year(s) Of Engagement Activity 2013
URL http://www.dailymail.co.uk/news/article-2342905/DNA-clue-help-beat-dieback-plague-killing-Britains-a...
 
Description Discussions with DEFRA about ash research requirements 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Discussion with DEFRA officials about the impact of current research on ash dieback, notably research at JIC, for policy on control of ash dieback and for international trade in live plants, timber and firewood. These conclusions of the discussion fed into a strategy meeting held in January 2019 and will thus feed into a strategy document being written by DEFRA.
Year(s) Of Engagement Activity 2018
 
Description East Anglia: Ash Dieback and other tree diseases one year on: East Anglian Daily Times-13 Oct 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Described the progress of ash dieback disease in Norfolk a year after its discovery in Norfolk
Year(s) Of Engagement Activity 2013
URL http://www.eadt.co.uk/news/east_anglia_ash_dieback_and_other_tree_diseases_one_year_on_1_2872560
 
Description European Research Council@10: the impact on science and scientists 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Scientists at the John Innes Centre and The Sainsbury Laboratory reflect on the success of the ERC over the last ten years and the impact that ERC grants have had on their science and their careers. Category: Science & Technology
Year(s) Of Engagement Activity 2017
URL https://youtu.be/qEgjYaMG0tQ
 
Description Facebook game Fraxinus targeted at beating ash dieback;The Guardian-13 Aug 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Describe how the public could help with DNA sequence analysis in ash dieback research using the computer game Fraxinus
Year(s) Of Engagement Activity 2013
URL https://www.theguardian.com/environment/2013/aug/13/ash-dieback-facebook-fraxinus-game
 
Description Fraxinus: the Facebook game where players crack the genetic code : The Independent-14 Aug 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described how we had established a computer game to enable the public help with NA sequence analysis in ash dieback disease
Year(s) Of Engagement Activity 2013
URL http://www.independent.co.uk/life-style/gadgets-and-tech/news/fraxinus-the-facebook-game-where-playe...
 
Description Fraxinus: the Facebook game where players crack the genetic code; The Independent-14 Aug 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Described how to access the Fraxinus game that enabled the public to help with analysis of genome sequences related to ash dieback disease
Year(s) Of Engagement Activity 2013
URL http://www.independent.co.uk/life-style/gadgets-and-tech/news/fraxinus-the-facebook-game-where-playe...
 
Description Friends of JIC 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact The John Innes Centre scientists regularly inform a 'Friends' group of interested parties about new scientific developments. This combined presentation was very well attended, and was followed by a lively discussion about ash dieback
Year(s) Of Engagement Activity 2013
 
Description Fungicide on ash dieback pathogen 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Briefing the public on the potential use of fungicides on ash dieback based on genome sequence analysis indicating sensitivity to fungicides
Year(s) Of Engagement Activity 2014
URL http://www.bbc.co.uk/news/uk-england-25964365
 
Description Genetic secrets of resistant tree gives new hope over ash dieback; The Independent-16 Jun 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described the release of genome sequence data for a Danish ash tree resistant to as dieback diease and how this would help identify other similar trees
Year(s) Of Engagement Activity 2013
URL http://www.independent.co.uk/news/uk/home-news/genetic-secrets-of-resistant-tree-gives-new-hope-over...
 
Description Hilary Geoghegan visit 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Media (as a channel to the public)
Results and Impact We invited Hilary Geoghegan, an expert in citizen science at University of Reading, to come and discuss, assess ad comment upon our approach to citizen science' related to ash dieback.
Year(s) Of Engagement Activity 2013
 
Description IS-MPMI Interactions: InterViews: Sophien Kamoun by Jixiang Kong 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact This InterView with Sophien Kamoun, John Innes Centre, was performed by one of the 2016 IS-MPMI student travel awardees, Jixiang Kong, Gregor Mendel Institute.

JIXIANG KONG: What led you to study biology? More specifically plant-pathogen interactions.

SOPHIEN KAMOUN: I grew up with a passion for nature. As a teenager I collected insects and became fascinated by their incredible diversity. Later I took this "hobby" more seriously and I specialized in studying tiger beetles. I even published a few papers on this topic.

After high school in Tunisia, I went to Paris with the firm intention of studying biology and becoming an entomologist. However, I was disappointed by how badly taught zoology was-too much emphasis on taxonomy and little mechanistic thinking. Instead, I became drawn to the more rigorous methods and approaches of molecular biology, and I ended up majoring in genetics. I reconciled this major with my natural history interests by taking multiple modules in evolution and reading a lot on the subject.

Plant pathology came later when I moved from Paris to the University of California-Davis for my Ph.D. The fellowship I received stipulated that I should study plant biology. It wasn't by choice but rather by accident. But I quickly became engrossed in molecular plant pathology and I really liked that this science involves interactions between multiple organisms. However, for many years I missed a direct connection between the lab work and the field.

JK: If you would not have chosen the topic of plant-pathogen interactions, what would you choose?

SK: Definitely, entomology. I'm still fascinated by insects, especially beetles. I feel we know so little about their biology, especially from a mechanistic angle. They are so diverse and yet most insect research focuses on a few species, such as Drosophila. There are so many fascinating questions, for example, about the evolution of insect behavior and the underlying genes. Also, insects can be important crop pests and disease vectors. This is a very fertile area of research that I highly recommend to early career scientists.

JK: How do you envision large-scale "omics" approaches in studying plant immunity?

SK: Omics are just another tool. They're powerful tools but they're still methods we use to answer questions. I advise everyone to frame their research based on questions and then look for the best methods to answer these questions.

This said, genomics has transformed biology in a fundamental way. It's a new way of doing business. We now have catalogs of plant and pathogen genes, so the challenge is to link genes to function rather than discovering the genes per se. Another key aspect is that genomics is a great equalizer. Model systems are less important than in earlier days. One can make a lot of progress with a genome and a few functional assays. For example, consider the progress made in discovering effectors in obligate parasites. This would have been almost unthinkable in the pre-genomics age. This is why I wish to see more early career scientists explore the diversity of pathogen systems rather than working on established model systems.

JK: Social media is changing the way of communication rapidly. However, the scientific communication on social media is just emerging. How do you see the direction of social media in the future regarding the impact on science? Will social media replace or minimize some conventional communication such as conferences?

SK: Communication is an essential function of being a scientist. We're not only in the business of producing new knowledge but it's also our obligation to communicate knowledge to our peers and the public. These days social media became a major medium for communication in science. It's an efficient way to filter through the incessant flow of information, stay up to date, and broadly broadcast new knowledge. It also enables us to expand our network way beyond traditional colleagues. I interact on Twitter with teachers, farmers, journalists, etc. I also use it, of course, to communicate with colleagues and share information and insights. I also find Twitter immensely entertaining. Scientists have a lot of humor.

I don't think social media will replace the need for direct contact and interaction between peers. I think we still would want to break off our daily routine and meet in person with colleagues. However, I wish we could start rethinking the format of scientific conferences. Both the fairly detailed oral presentations and poster sessions could be improved if they were combined with some sort of Internet interaction. Twitter is already transforming how scientists interact at conferences but we could do better.

JK: What advice would you provide to young researchers who are in their early scientific career?

SK: Don't follow the herd. Take chances. Look beyond the current trends both in terms of experimental systems and questions, and ask provocative questions.
Year(s) Of Engagement Activity 2017
URL https://www.ismpmi.org/members/Interactions/Lists/Posts/Post.aspx?ID=152
 
Description ITV News: Betty 22 April 2016 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Interview described the identification of a UK tree with low ash dieback susceptibility and the use of genetic markers to identify such trees
Year(s) Of Engagement Activity 2016
URL http://www.itv.com/news/anglia/2016-04-22/norfolk-ash-tree-could-be-key-to-fighting-dieback-disease/
 
Description ITV interviews Aug 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact ITV news interview describing progression of ash dieback in the UK and how BBSRC/DEFRA-funded research was being used to understand the genomes of the ash tree and the ash dieback pathogen. It also described the 'Fraxinus' game that engaged the public in helping analyse DNA sequences from that research
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/08/gamers-to-join-ash-dieback-fight-back/
 
Description Interview for BBC East Anglia TV: Ash dieback -one more fungal spore 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interview for BBC East Anglia television to discuss and interpret findings published in Nature Ecology and Evolution that week. The total news reach estimated from this round of interviews was 5.56m with an estimated value of £51,410. The estimated reach of this program was 412,000 with a value of £2,062.
Year(s) Of Engagement Activity 2018
 
Description Interview for BBC Norfolk local radio (Live): Ash dieback -one more fungal spore 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Live interview for BBC Norfolk Radio to discuss and interpret findings published in Nature Ecology and Evolution that week. The total news reach estimated from this round of interviews was 5.56m with an estimated value of £51,410. The estimated reach of this program was 35,167 with a value of £1,272. The primary objective was to inform the public of research going on at the Earlham Institute as well as to update them on the latest ash dieback research.
Year(s) Of Engagement Activity 2018
 
Description Interview for BBC Radio 4 Farming Today: Ash dieback -one more fungal spore 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Interview for BBC Radio 4 Farming Today program to discuss and interpret findings published in Nature Ecology and Evolution that week. The total news reach estimated from this round of interviews was 5.56m with an estimated value of £51,410. The estimated reach of this program was 2,996,500 with a value of £17,996.
Year(s) Of Engagement Activity 2018
 
Description Interview for ITV Anglia TV: Ash dieback -one more fungal spore 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interview for BBC Norfolk Radio to discuss and interpret findings published in Nature Ecology and Evolution that week. The total news reach estimated from this round of interviews was 5.56m with an estimated value of £51,410. The estimated reach of this program was 555,500 with a value of £2,227.
Year(s) Of Engagement Activity 2018
 
Description Interview with Matthew Gudgin on BBC Radio 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Sophien Kamoun's interview with Matthew Gudgin on BBC Radio following election as Fellow of the Royal Society. This includes a discussion of plant blindness.
Year(s) Of Engagement Activity 2018
URL http://kamounlab.tumblr.com/post/173740235230/sophiens-interview-with-matthew-gudgin-on-bbc
 
Description Invited speaker: Aarhus University (Denmark) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited to the Aarhus University departmental seminar series to talk about ash dieback invasions and sugar beet rust experiments.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker: Sheffield University 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited to the Sheffield departmental seminar series to talk about ash dieback invasions and sugar beet rust experiments.
Year(s) Of Engagement Activity 2018
 
Description John Innes Centre scientist awarded British Empire Medal; Norfolk Eastern Daily Press-2 Jan 2015 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Anne Edwards was interviewed about ash dieback disease in the context of her award of the British Empire Medal or her work on science in the community
Year(s) Of Engagement Activity 2015
URL http://www.edp24.co.uk/news/environment/john_innes_centre_scientist_awarded_british_empire_medal_for...
 
Description Key Note Speaker at VIII Argentinian Bioinformatics and Computational Biology Congress 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Key note speaker - meeting was followed by a number projects to apply for GCRF funding to work with researchers in Latin America
Year(s) Of Engagement Activity 2017
URL http://ufq.unq.edu.ar/8cab2c/
 
Description Keynote lecture at ICPP 2018: The Edge of Tomorrow - Plant Health in the 21st Century 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact ICPP2018 International Congress of Plant Pathology Plenary Session - Plant Health is Earth's Wealth, Boston, USA, Monday, July 30, 2018

The talk was broadcast on a live stream and is available on YouTube https://youtu.be/MYysIKSYY_8
Year(s) Of Engagement Activity 2018
URL http://kamounlab.tumblr.com/post/176385835530/the-edge-of-tomorrow-plant-health-in-the-21st
 
Description Le Professeur tunisien Sophien Kamoun intègre la prestigieuse Royal Society de Londres 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact News article in the North African media https://www.huffpostmaghreb.com
Year(s) Of Engagement Activity 2018
URL https://www.huffpostmaghreb.com/entry/le-professeur-tunisien-sophien-kamoun-integre-la-prestigieuse-...
 
Description Mustard TV on Betty 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Identification of Betty, a local ash tree showing low susceptibility to ash dieback and predicted to be resistant based on genetic markers
Year(s) Of Engagement Activity 2016
URL http://www.mustardtv.co.uk/browse/betty-the-norfolk-ash-tree-could-hold-key-in-fightback-against-dea...
 
Description Mustard TV on ash tree losses 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Explaining why ash trees in Norwich were being cut down due to ash dieback disease
Year(s) Of Engagement Activity 2016
URL http://webcache.googleusercontent.com/search?q=cache:YXTJ9NV4Bp8J:www.mustardtv.co.uk/browse/the-cos...
 
Description Nature Ecology and Evolution blog: Ash dieback -behind the paper 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact These behind the paper blog posts are an opportunity to interpret the results of your paper to a more general audience. In this case I wrote about the the ash dieback paper published in Nature Ecology and Evolution. This platform also provided an opportunity to describe how I came to the project which could be useful to earlier career researchers
Year(s) Of Engagement Activity 2018
URL https://natureecoevocommunity.nature.com/users/92501-mark-mcmullan/posts/32660-behind-the-ash-diebac...
 
Description Norwich Research Park scientists help identify ash dieback tolerance in trees: Norfolk Eastern Daily Press-27 Dec 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Described genetic markers that identify trees with low ash dieback disease susceptibiity
Year(s) Of Engagement Activity 2016
URL http://www.edp24.co.uk/news/environment/norwich_research_park_scientists_help_identify_ash_dieback_t...
 
Description Norwich Science Festival 2018: Trees on the Brink: Evolution of the Ash Dieback Pathogen 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact An opportunity to describe the recent ash dieback publication to the public at the annual Norwich Science Festival. The audience appeared to be made of a wide and diverse group of people and their were questions from young (school age) and more senior (retired) members of the community.
Year(s) Of Engagement Activity 2018
URL https://norwichsciencefestival.co.uk/events/trees-on-the-brink/
 
Description Presentation in the 4th Plant Genomics Congress (May 2016) - London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact I presented about the tools developed within TransPlant and about the Ash Tree genome project.
Year(s) Of Engagement Activity 2016
 
Description Press Briefing: Science Media Cenre Aug 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Press briefing about ash dieback and the release of the computer game Fraxinus to help engage the public in analysis of DNA sequence reads associated with ash dieback research. This resulted in a wave of publicity that was very important to get the game taken up widely. Over 25,000 players contributed to analyses.
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/08/gamers-to-join-ash-dieback-fight-back/
 
Description Press Conference Final Report 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact This described the content of the Nornex final report as submitted to BBSRC and DEFRA. The report was based around the identification of a UK tree that was predicted to have low disease susceptibility and was seen to have low levels of disease in a highly infected area. There were many questions and many associated newspaper reports along with TV and radio broadcasts
Year(s) Of Engagement Activity 2016
 
Description Press event for publication of Defra Nornex report on ash dieback, Norwich 22/4/16 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Press event for publication of Nornex report on ash dieback, Norwich 22/4/16
Year(s) Of Engagement Activity 2016
 
Description Press release on occasion of the ash tree genome publication in Nature 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Press release with quotes and other comments on occasion of the publication of the ash tree genome in Nature.
Year(s) Of Engagement Activity 2016
URL http://www.niab.com/news_and_events/article/395
 
Description Press release relating to publication on ash dieback disease 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Press release relating to publication on ash dieback disease, which drew responses from the public.
Year(s) Of Engagement Activity 2016
URL http://www.bbsrc.ac.uk/news/fundamental-bioscience/2016/161226-pr-could-disease-tolerance-genes-give...
 
Description Press release relating to publication on ash dieback disease 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Press release relating to publication on ash dieback disease 2016
Year(s) Of Engagement Activity 2016
URL https://www.york.ac.uk/news-and-events/news/2016/research/ash-dieback-screening/
 
Description Public engagement video 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact A video published by the Microbiology Society tries to explain what is Ash dieback disease
Year(s) Of Engagement Activity 2017
URL https://www.ponteproject.eu/factsheets-hf/
 
Description Radio Norfolk Aug 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interview about ash dieback research being done locally involving John Innes Centre, The Sainsbury Laboratory and The Genome Analysis Centre (Now Earlham Institute) and how the public could get involved via playing the Fraxinus game
Year(s) Of Engagement Activity 2013
URL https://www.jic.ac.uk/news/2013/08/gamers-to-join-ash-dieback-fight-back/
 
Description Radio Norfolk Oct 2013 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Description of ash dieback symptoms and progression of the disease in Ashwellthorpe Wood in Norfolk
Year(s) Of Engagement Activity 2013
 
Description Scientists move closer to ash tree resistant to dieback; Telegraph.co.uk-17 Jun 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Described the release of genome sequence of a Danish ash tree resistant to ash dieback disease and how this information could be used to identify and predict similar trees with low susceptibility
Year(s) Of Engagement Activity 2013
URL http://www.telegraph.co.uk/gardening/10123431/Scientists-move-closer-to-ash-tree-resistant-to-diebac...
 
Description Scoop.it page "Plants and Microbes" 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Everything related to the science of plant-microbe interactions. Curated by Kamoun Lab @ TSL

>450K page views.
Year(s) Of Engagement Activity 2013,2014,2015,2016,2017
URL https://www.scoop.it/topic/mpmi
 
Description Six ways Norwich scientists are helping the world; Norfolk Eastern Daily Press-21 Apr 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Described the scientific approaches being taken to deal with ash dieback disease
Year(s) Of Engagement Activity 2016
 
Description SlideShare: Pathogenomics of emerging plant pathogens: too little, too late 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Slides: Pathogenomics of emerging plant pathogens: too little, too late. Presented at the conference "Building resilience against crop diseases: A global surveillance system", February 14, 2018, Rockefeller Foundation Bellagio Center in Lake Como, Italy.
Year(s) Of Engagement Activity 2018
URL https://www.slideshare.net/SophienKamoun/pathogenomics-of-emerging-plant-pathogens-too-little-too-la...
 
Description Stranger in a strange land: the experiences of immigrant researchers 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Published in Genome Biology: Continuing with our Q&A series discussing issues of diversity in STEM fields, Genome Biology spoke with three researchers on their experiences as immigrants.

International collaborations are key to advancing scientific research globally and often require mobility on the part of researchers. Migration of scientists enables the spread of ideas and skills around the world, giving researchers the opportunity to follow the best resources. Of course, migration adds a new set of challenges to the already monumental task of starting and running a lab. Genome Biology spoke to Sophien Kamoun, Rosa Lozano-Durán, and Luay Nakhleh about their personal experiences.

What influenced your choice to move to your current country?

SK: There is this old German expression "wo die Musik spielt"-you go where it's happening, where the "music is played". I think that sums it up. When I was a student in the 1980s, almost everyone wanted to do a Ph.D. in the USA. I felt that to have the best training and to be among the best, I had no choice but to study in the USA. I think that was a pretty correct assessment of the state of affairs in the 1980s. Indeed, I had a fantastic experience at the University of California, Davis. Also, at that time, Europe wasn't really open to non-Western scientists, and international mobility wasn't recognized like it is today [1]. Later, I moved to the Netherlands and then back to the USA before landing in my current position at The Sainsbury Laboratory (TSL) in Norwich, UK. I moved to Norwich exactly 10 years ago, primarily because of the reputation of the laboratory as a center of excellence for plant pathology research and the generous support provided by David Sainsbury through the Gatsby Foundation. I have had a phenomenal time at TSL these past 10 years, where I have had the opportunity to work with outstanding scientists from perhaps about 30-40 countries. An interesting point is that when TSL was founded in 1988, all the group leaders were British [2], but currently our principal investigators are from all over the world [3]. I think TSL truly reflects the emergence of the #ScienceisGlobal movement on social media [4], which is so evident in the UK and other corners of Europe.

RL-D: Three years ago, having worked as a postdoctoral researcher for almost four years, I was eager to establish my own laboratory. I had known what I wanted to devote my research to for a long time and could not wait to get started. Unfortunately, the economic climate in Europe, where I am originally from and where I was working at the time, was not particularly propitious for science in academia, with research budgets being slashed and increasing competition-not the most favorable situation for new group leaders, I heard over and over again. My partner was also a scientist at the same career stage, and so we needed to find two positions, not just one, complicating matters even more. One day, just by chance, we came across a job advertisement for group leader positions at the Shanghai Center for Plant Stress Biology in China. We had heard about the place-a new institute with the ambition to become a powerhouse for plant sciences. I was very excited at the prospects of leading my own research group, and that excitement overrode any qualms or self-imposed geographical restrictions. I am also fortunate enough to have an incredibly supportive family and friends who unconditionally encouraged me to pursue my scientific career, even if that involved moving far away; they may not always understand the nitty-gritty details of what I do, but they know how important it is for me.
It was my first job application, and I was offered the position following an interview at the center. They were willing to support me and give me the freedom to develop my own research program-it was an unbeatable opportunity to start my independent career. And the fact that I would be living in Asia, with the immense chance to broaden my experience that entailed, added some extra appeal (despite the slight vertigo I also felt). There was not much to think about, really-it was a deal I simply could not turn down.

LN: I was born to a Christian Arab family in Israel and did my undergraduate studies at the Technion (Israel Institute of Technology). Although I was an atheist by the time I started my studies at the Technion, I still considered myself to be "culturally" Christian, in that I celebrated Christmas and New Year with my family (eating and drinking, not going to church!). However, almost every year, my exams were scheduled on December 25th and January 1st (the Fall semester in Israel starts in October and ends in February). Being unable to take exams on different dates affected my performance in my studies and my interest in pursuing graduate studies at the same institution. Also, more generally, I was the only Christian Arab student in my class, and one of a handful of Arab students; I never felt comfortable at the time. So, I decided to pursue graduate studies in computer science outside Israel. The choice to come to the USA was an easy one because the USA had (and still has, in my opinion) the best graduate programs in computer science.
Year(s) Of Engagement Activity 2017
URL https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1370-4
 
Description Talking Biotech Podcast - Plant Disease Networks 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Plant disease resistance is a complicated arms race between the plant and pathogens. Bacteria, viruses and fungi evolve in lock-step with plants, creating new ways to overcome new disease resistance strategies. Resistance to disease has a foundation in the gene-for-gene model, a model that hypothesizes that plants and pathogens have a molecular relationship with each other that mediates pathogenicity. Today's podcast features Drs. Lida Derevnina and Chih-Hang Wu, postdoctoral researchers with Sophien Kamoun (@KamounLab) at the Sainsbury Laboratory (@TheSainsburyLab) in Norwich, England. They describe the new thinking of disease resistance as a number of complex layers that integrates many gene-for-gene interactions with other mechanisms in mediating plant defense. Hosted by Paul Vincelli (@pvincell).
Year(s) Of Engagement Activity 2018
URL http://www.talkingbiotechpodcast.com/146-plant-disease-networks/
 
Description Taproot Episode 1, Season 1: Extreme Open Science and the Meaning of Scientific Impact 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact The Taproot is the podcast that digs beneath the surface to understand how scientific publications in plant biology are created. In each episode, co-hosts Liz Haswell and Ivan Baxter take a paper from the literature and talk about the story behind the science with one of its authors.

This episode features Sophien Kamoun, a Senior Scientist at the Sainsbury Laboratory in Norwich, UK. He was born in Tunisia, and got his Maitrise from Pierre & Marie Curie Univ., Paris, France. He then moved to the United States where he did both a Ph.D. and postdoc at the University of California, Davis. He then went to Wageningen University in The Netherlands, where he was a Senior Research Scientist for three years. Sophien started as an Assistant Professor in the Department of Plant Pathology at Ohio State University, Wooster, where he rose through the ranks to Full Professor before moving in 2007 to the Sainsbury Lab where he has been ever since. During this time he was Head of the Laboratory for several years. He has received many awards, and is an elected member of AAAS and EMBO, and has served on many editorial boards.

In this episode, the hosts and Sophien discuss a recent collaborative paper (Islam et al., 2016, BMC Biology) that really embodies the concepts of open science. It addresses the source and characterization of a newly discovered wheat blast in Bangladesh. Wheat blast is a fungal disease that affects grasses that are a huge threat to food security. The authors report the geographical distribution of this new disease, characterize the disease symptoms of affected plants, and isolate and validate the causal fungus. Most strikingly, they performed RNA sequencing on symptomatic and asymptomatic leaves and show that RNA from these infected leaves aligns to the genome of a Brazilian wheat blast strain. They conclude that the Bangladesh isolate of wheat blast is phylogenetically related to the Brazilian wheat blast, rather than an unknown or new lineage.

Listen to this episode to hear Sophien, Ivan, and Liz discuss the science in this paper, how the project started, and how it developed into a peer-reviewed publication. Also discussed is the importance of redefining what is meant by scientific "impact", and new ways to do science in the plant pathology community and beyond
Year(s) Of Engagement Activity 2017
URL https://plantae.org/taproot-episode-1-season-1-extreme-open-science-and-the-meaning-of-scientific-im...
 
Description Urgent action needed over plant disease skills shortage; Norfolk Eastern Daily Press-11 Mar 2014 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Press release about shortages of trained plant pathologists was explained in the context of ash dieback disease and the kinds of work that such scientists can do
Year(s) Of Engagement Activity 2014
URL http://www.edp24.co.uk/news/politics/urgent_action_needed_over_plant_disease_skills_shortage_mps_1_3...
 
Description Web chat 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Live web chat on ash dieback aimed at informing the public, foresters and press about ash dieback and what steps could be taken to ameliorate consequences
Year(s) Of Engagement Activity 2013
 
Description What's up with preprints? And why I'm bothering with them. 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact What's up with preprints? And why I'm bothering with them. A few answers to @hormiga post about why he's not bothering with preprints.
Year(s) Of Engagement Activity 2017
URL http://kamounlab.tumblr.com/post/163409024195/whats-up-with-preprints-and-why-im-bothering
 
Description Woodland devastated by ash dieback could be restored: Telegraph.co.uk-8 Mar 2013 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Describes BBSRC/DEFRA award and how we hoped to use it to find trees resistant to ash dieback
Year(s) Of Engagement Activity 2013
URL http://www.telegraph.co.uk/gardening/plants/trees/9917160/Woodland-devastated-by-ash-dieback-could-b...
 
Description You Tube on Fraxinus and genomes 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Explanation of difficulties associated with DNA sequence assembly and how the game Fraxinus can help analyse DNA sequence reads to give better assemblies that can be used to understand ash dieback disease
Year(s) Of Engagement Activity 2013
URL https://www.youtube.com/watch?v=Ny_VozK_v9Q