Food Microbiome and Health: Elucidating how foods influence host responses
Lead Research Organisation:
Quadram Institute
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
To gain mechanistic insights into how plant-based foods and food-induced changes in the GIT microbiome affect host responses within and beyond the GIT
Planned Impact
unavailable
Publications
Beraza N
(2023)
Ketohexokinase-C: The mechanistic link between dietary sugars and protein acetylation during liver steatosis.
in Journal of hepatology
Bernuzzi F
(2023)
Sulforaphane rewires central metabolism to support antioxidant response and achieve glucose homeostasis.
in Redox biology
Eguchi T
(2024)
The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response
in Journal of Cell Biology
Juge N
(2023)
Encyclopedia of Cell Biology
Quesada-Vázquez S
(2023)
Potential therapeutic implications of histidine catabolism by the gut microbiota in NAFLD patients with morbid obesity
in Cell Reports Medicine
Teng NMY
(2023)
Allocoprobacillus halotolerans gen. nov., sp. nov and Coprobacter tertius sp. nov., isolated from human gut microbiota.
in International journal of systematic and evolutionary microbiology
| Description | DTP |
| Amount | £80,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2024 |
| End | 09/2028 |
| Description | DTP PhD Studentship |
| Amount | £80,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2024 |
| End | 09/2028 |
| Description | MMB DTP |
| Amount | £80,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2023 |
| End | 09/2027 |
| Description | NRPDTP |
| Amount | £80,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2024 |
| End | 09/2028 |
| Description | NRPDTP CASE |
| Amount | £80,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2024 |
| End | 09/2028 |
| Description | NRPDTP VitB12 |
| Amount | £80,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2019 |
| End | 06/2024 |
| Description | The Norwich Research Park Biosciences Doctoral Training Partnership |
| Amount | £18,000,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2023 |
| End | 09/2027 |
| Description | international partnering award Spain |
| Amount | £10,000 (GBP) |
| Organisation | Quadram Institute Bioscience |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 02/2024 |
| End | 06/2024 |
| Title | transgenic animals |
| Description | With this funding we have been able to complete our generation of single and double endothelial cell specific knockouts of alpha5 integrin beta3 integrin and neuropilin-1 |
| Type Of Material | Model of mechanisms or symptoms - mammalian in vivo |
| Year Produced | 2017 |
| Provided To Others? | No |
| Impact | We will share these tools if asked |
| Description | Collaboration with Melanie Rutkowski |
| Organisation | University of Virginia (UVa) |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Exchange of intellectual material |
| Collaborator Contribution | Exchange of intellectual material |
| Impact | Co-authors on manuscript under revision. Planning grant applications together. |
| Start Year | 2020 |
| Description | Single cell sequencing technology with EI |
| Organisation | Earlham Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Intellectual input (conceptualised the research project), trained staff , study supervision and obtained funding. |
| Collaborator Contribution | Provide expertise on single cell sequencing technology, trained staff, provided resources, supervision of this experimental part |
| Impact | no outputs yet. |
| Start Year | 2022 |
| Title | Bif and compositions thereof for BrCa treatment |
| Description | priotry patent application filed 21 December 2021 |
| IP Reference | GB2118611.9 |
| Protection | Patent application published |
| Year Protection Granted | 2021 |
| Licensed | No |
| Impact | Priority patent application filed 21 December 2021 |
| Description | Norwich Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Activity focused on liver regeneration and impact of unhelathy diets in liver health at the Norwich Science Festival. Reached over 300 children and carers. |
| Year(s) Of Engagement Activity | 2024 |