Computational Molecular Biology
Lead Research Organisation:
Roslin Institute
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
Ensuring the availability of suitable computational biology analysis software installations in conjunction with Harpenden and the Roslin IT group. This currently includes both EMBOSS and other packages on the Linux machines and Vector NTI on the desktop machines. 1) Provision and maintenance of local copies of public and private sequence and other datasets in conjunction with Harpenden (public data set provision) and key local groups (Bioinformatics group, ARK-Genomics and others). 2) Provision and maintenance of local sequence search capabilities using those locally available data sets in conjunction with Harpenden and the key local groups and maintenance of a list of those search sets to inform all research groups. 3) Ensuring that the configuration of local Vector NTI installations utilises those local search provisions. 4) Provision of tailored local training in computational biology analysis tools and techniques for small groups, using materials provided by Harpenden and developed locally. 5) Provision of small-scale analysis service to support low- usage groups. 6) Provision of advice on analysis tools via regular `drop-in clinic. 7) Investigation of novel algorithm and tool development ahead of requirements. 8) Evangelisation of computational biology analysis possibilities through pro-active interaction with research groups. 9) Provision of strategic advice to IS/IT Strategy Committee on computational biology analysis requirements and opportunities.
Planned Impact
unavailable
Organisations
Publications
Connelley T
(2009)
Genomic analysis reveals extensive gene duplication within the bovine TRB locus.
in BMC genomics
Connelley T
(2009)
Genomic and cDNA analysis of the bovine TCRß gene repertoire
in Veterinary Immunology and Immunopathology
Lu ZH
(2011)
Strain-specific copy number variation in the intelectin locus on the 129 mouse chromosome 1.
in BMC genomics
McBride D
(2009)
01-P012 The role of micro-RNAs in the development of the chick gonads
in Mechanisms of Development
Wilkinson S
(2013)
Signatures of diversifying selection in European pig breeds.
in PLoS genetics
| Description | BBSRC Response Mode |
| Amount | £57,495 (GBP) |
| Funding ID | BB/P024629/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2017 |
| End | 06/2018 |
