Patient Specific Modelling Network

Lead Research Organisation: Swansea University
Department Name: College of Engineering

Abstract

Over the last five years the interest in developing patient-specific numerical solution to human body related problems has grown tremendously. This is due to the fact that both computing power and appropriate tools needed to carry out such studies have been emerging over the last few years. Although there are a large number of difficulties remain to be addressed, the patient-specific numerical modelling has great potential to study and understand several aspects of human body related illnesses, which are otherwise not possible. For instance, a detailed and prolong flow structure near an aortic aneurysm is only possible via a fluid dynamics study. Such a flow pattern and associated forces will help the surgeons to plan a surgery on an aortic aneurysm. Patient-specific studies will also give us the post-operative conditions a priori to a surgery and help the clinicians to make decisions. Many other examples of biomechanics, respiratory systems and urinary tract can be studied in a patient-specific sense. In short, a patient-specific study constructs a full picture from minimum available patient-specific information.The proposed network will bring a group of people from different disciplines together to address the difficulties faced by patient-specific modelling community and support a faster growth in this area. The network will pay particular attention to exploring the possibility of providing support to NHS trust hospitals. At least four formal workshops will be held during the proposed period of the network to move the research forward in the area of patient-specific modelling. A dedicated webpage will be developed and hosted from Swansea. This webpage will have a robust database for registered participants to upload and share patient-specific modelling related material. All the attempts will be made beyond the project period to sustain the network. This includes conducting larger workshops, approaching other funding agencies, charities and private medical industries.

Publications

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Boileau E (2015) A benchmark study of numerical schemes for one-dimensional arterial blood flow modelling. in International journal for numerical methods in biomedical engineering

 
Description The main objective of this project was to bring together patient-specific modelling scientists in the UK to build a scientific network. This was carried out through four meetings at various locations in the UK. The first meeting was held at Swansea University, second in University of Edinburgh, third at Imperial College London and the last one at Cardiff University College of Medicine. From the beginning the network was driving towards the goal of using patient-specific modelling tools to solve clinical problems. It was also aiming to drive the research towards translation. The growth of research in this area during the network period was phenomenal and this area is currently at the interface between research and translation. The patient-specific modelling network played a major role in this development and will continue to do so through the newly formed conference 'UK National Conference on Patient-Specific Modelling and Translational Research'. Details of all the activities and information on past meetings are available on the network website at 'www.patientspecific.net'.

The national conference is now taken over by the Institute of Physics and Engineering in Medicine (IPEM). The PI is helping to put together a plan to organise the next conference.
Exploitation Route This was a network grant. The objective was networking. The main objectives of taking subject-specific modelling closer to clinic have been achieved through network meetings. The next step is to translate the modelling software developed around the country to clinics. This is long term process.

The network will be taken over by IPEM as a national conference.
Sectors Healthcare

URL http://www.patientspecific.net