Synthesis and Characterisation of Dual Functional Nanoparticles for Probing the Role of Reactive Oxygen Species in Cellular Function
Lead Research Organisation:
Durham University
Department Name: Chemistry
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Organisations
People |
ORCID iD |
| Andrew Beeby (Principal Investigator) |
Publications
Benstead M
(2011)
Addressing fluorescence and liquid crystal behaviour in multi-mesogenic BODIPY materials
in New Journal of Chemistry
Giuntini F
(2012)
Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices.
in Nanoscale
Laakso J
(2012)
Synthesis of chlorin-sensitized near infrared-emitting lanthanide complexes.
in Inorganic chemistry
Scholten J
(2012)
Anomalous reversal of C-H and C-D quenching efficiencies in luminescent praseodymium cryptates.
in Journal of the American Chemical Society
Giuntini F
(2014)
Conjugatable water-soluble Pt(II) and Pd(II) porphyrin complexes: novel nano- and molecular probes for optical oxygen tension measurement in tissue engineering.
in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Rosser Geraldine Ann
(2015)
A spectroscopic study on nanosensors and porphyrins for bioimaging
Bryden F
(2018)
Assembly of High-Potency Photosensitizer-Antibody Conjugates through Application of Dendron Multiplier Technology.
in Bioconjugate chemistry
| Description | This work focused the preparation of nanoparticles containing molecules such as photosensitisers and molecular probes. These nanoparticles can be used as both probes of their local environment, and also to cause perturbations to this environment, along cause and effect to be investigated. |
| Exploitation Route | The routes to preparing the nanoparticles and the general techniques for the covalent coupling of molecular species to the interior or exterior, and of physical entrapment within these nanoparticles has been demonstrated, as has the effects of these upon the photophysical properties of the species. These may have applications beyond the original proposal |
| Sectors | Chemicals Healthcare Security and Diplomacy |
| Description | The PhD student carrying out the work, Dr Rosser, became closely involved with Outreach activities. |
| First Year Of Impact | 2014 |