Rapid catalytic disinfection of surfaces, PPE and transportation
Lead Research Organisation:
Cardiff University
Department Name: Chemistry
Abstract
Cardiff University and Selden Research have a patented novel catalytic method of making long lived reactive oxygen species effective for pathogen kill and surface disinfection. https://patentimages.storage.googleapis.com/12/c4/b7/8f1ef5827dc436/GB2572364A.pdf
The method involves passing an environmentally benign solution containing dilute hydrogen peroxide (H2O2) using a spray bottle through a catalyst (a copper salt on alumina matrix) incorporated in the nozzle. We have tested this with a range of microorganisms including
Staphylococcus aureus and Candida albicans yeast and have achieved 99.999% reduction in minutes. To date we have not examined virucidal activity but given the effect of our method on other microorganisms we anticipate it will be effective against enveloped viruses. Our work until
now focussed on developing the method for the food preparation and agricultural industries and the key point is that no toxic residues remain on the surfaces that are treated, while also offering exceptional kill efficacy and compatibility with the surfaces treated.
The research programme will initially test the virucidal activity of our existing formulation on viruses including coronavirus standard test strain as a surrogate for SARS-CoV-2 (COVID-19). We will then aim to modify and simplify the formulation to determine if we can replace hydrogen
peroxide by air whilst maintaining the virucidal activity. We will also develop the use of aerosols so that the new method can be used to treat large spaces which could be applied in the disinfection of PPE for reuse or the environmentally non-toxic disinfection of transportation such as the internal spaces of ambulances, buses, trains and planes.
The method involves passing an environmentally benign solution containing dilute hydrogen peroxide (H2O2) using a spray bottle through a catalyst (a copper salt on alumina matrix) incorporated in the nozzle. We have tested this with a range of microorganisms including
Staphylococcus aureus and Candida albicans yeast and have achieved 99.999% reduction in minutes. To date we have not examined virucidal activity but given the effect of our method on other microorganisms we anticipate it will be effective against enveloped viruses. Our work until
now focussed on developing the method for the food preparation and agricultural industries and the key point is that no toxic residues remain on the surfaces that are treated, while also offering exceptional kill efficacy and compatibility with the surfaces treated.
The research programme will initially test the virucidal activity of our existing formulation on viruses including coronavirus standard test strain as a surrogate for SARS-CoV-2 (COVID-19). We will then aim to modify and simplify the formulation to determine if we can replace hydrogen
peroxide by air whilst maintaining the virucidal activity. We will also develop the use of aerosols so that the new method can be used to treat large spaces which could be applied in the disinfection of PPE for reuse or the environmentally non-toxic disinfection of transportation such as the internal spaces of ambulances, buses, trains and planes.
| Description | We have confirmed that our disinfection approach can kill viruses such as a surrogate for the SRAS-COV-2 virus. We are now working on an effective delivery method. We have found a way to stabilise teh active formulation and devised the delivery method. We are considering new IP at this satge. |
| Exploitation Route | Th e plan is to use the new method of disinfection of surfaces to be commercialised and used by the public. |
| Sectors | Healthcare,Leisure Activities, including Sports, Recreation and Tourism,Culture, Heritage, Museums and Collections,Retail,Transport |
| Description | Our industrial partner Selden Research have patented the work and are currently seeking ways to commercialise the new disinfectant product. |
| First Year Of Impact | 2022 |
| Sector | Chemicals,Healthcare,Leisure Activities, including Sports, Recreation and Tourism,Retail,Transport |
| Impact Types | Societal,Economic |
| Description | Selden |
| Organisation | Seldon Research Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | We link with Selden on surface disinfection studies. |
| Collaborator Contribution | Selden provide advice on surface disinfection and also carry out pathogen testing. |
| Impact | Selden have been carrying out pathogen testing. We have a patent in preparation and we plan a paper for submission to Nature group pubications. Seden are considering commercialisation. |
| Start Year | 2009 |