Biomanufacturing with carbon capture and utilisation: A Zero Carbon Loss System
Lead Research Organisation:
University of Surrey
Department Name: Chemical Engineering
Abstract
Nearly 140,000 industrial materials and chemicals are marketed worldwide. Most of them are made from fossil feedstocks with high CO2 emission embedded, and very low resources efficiency. To maintain the UK's global competitiveness, it is vital to identify sustainable alternatives for the manufacturing of these chemicals and materials.
Biomanufacturing, that utilises biological systems to produce commercially important biomaterials and biomolecules plays an important role in sustainable development, and has shown successful applications in manufacturing electronic components (e.g., bio-based flexible printed circuits), fine or specialty chemicals (e.g., bio-lubricants), building and construction (e.g., biocementation), consumer products (e.g., bio-based detergents), food (e.g., vitamin and amino acid fortification) and pharmaceuticals (e.g., vaccine production).
However, none of the current biomanufacturing routes has achieved zero carbon loss or emission. In fact, many bioprocesses (such as those involving fermentation) will emit large amounts of CO2. In a typical biomanufacturing, only 2/3 of the carbon resources flow ends up in final products, while the rest 1/3 are lost during the manufacturing process, in the form of CO2 emissions and residue wastes.
To address this challenge, the project will create the first-of-its-kind Zero Carbon Loss biomanufacturing system that will pave the way for the UK to reach the 2050 Net Zero target. This will be achieved by developing novel sustainable biomanufacturing of aromatics, heterocyclics and other lignocellulosics products with integrated carbon capture and utilization within the manufacturing process. These bio-based products, like building blocks of Lego, then will be used in different combinations to make various product such as pharmaceuticals, plastics, textile, composite materials, etc, with overall net zero carbon loss (emission and waste) throughout the manufacturing life cycle.
The technology innovation and resources optimisation of the BMCCU manufacturing route (WP1) will be guided by real-time system wide sustainability assessments (WP3), linked by an interoperable digital twin of the manufacturing process beyond the state of the art (WP2). It creates a new approach in which the lifecycle sustainability assessments will serve as an interactive decision-making tool fully embedded in the early-stage technology developments, rather than traditional retrospective assessment.
The project will contribute significantly to the UK's National Industrial Biotechnology Strategy, with a potential scope of £4.5 billion GVA, 63,000 jobs, and 2.5 billion tonnes of CO2 saving per year by 2030.
To achieve the vision, this proposal brings together a diverse multidisciplinary team from Loughborough University, Heriot-Watt University and Imperial College London, with world leading expertise in circular economy, intelligent manufacturing, industrial digitalisation and decarbonisation.
Biomanufacturing, that utilises biological systems to produce commercially important biomaterials and biomolecules plays an important role in sustainable development, and has shown successful applications in manufacturing electronic components (e.g., bio-based flexible printed circuits), fine or specialty chemicals (e.g., bio-lubricants), building and construction (e.g., biocementation), consumer products (e.g., bio-based detergents), food (e.g., vitamin and amino acid fortification) and pharmaceuticals (e.g., vaccine production).
However, none of the current biomanufacturing routes has achieved zero carbon loss or emission. In fact, many bioprocesses (such as those involving fermentation) will emit large amounts of CO2. In a typical biomanufacturing, only 2/3 of the carbon resources flow ends up in final products, while the rest 1/3 are lost during the manufacturing process, in the form of CO2 emissions and residue wastes.
To address this challenge, the project will create the first-of-its-kind Zero Carbon Loss biomanufacturing system that will pave the way for the UK to reach the 2050 Net Zero target. This will be achieved by developing novel sustainable biomanufacturing of aromatics, heterocyclics and other lignocellulosics products with integrated carbon capture and utilization within the manufacturing process. These bio-based products, like building blocks of Lego, then will be used in different combinations to make various product such as pharmaceuticals, plastics, textile, composite materials, etc, with overall net zero carbon loss (emission and waste) throughout the manufacturing life cycle.
The technology innovation and resources optimisation of the BMCCU manufacturing route (WP1) will be guided by real-time system wide sustainability assessments (WP3), linked by an interoperable digital twin of the manufacturing process beyond the state of the art (WP2). It creates a new approach in which the lifecycle sustainability assessments will serve as an interactive decision-making tool fully embedded in the early-stage technology developments, rather than traditional retrospective assessment.
The project will contribute significantly to the UK's National Industrial Biotechnology Strategy, with a potential scope of £4.5 billion GVA, 63,000 jobs, and 2.5 billion tonnes of CO2 saving per year by 2030.
To achieve the vision, this proposal brings together a diverse multidisciplinary team from Loughborough University, Heriot-Watt University and Imperial College London, with world leading expertise in circular economy, intelligent manufacturing, industrial digitalisation and decarbonisation.
Publications
Daniel T
(2024)
Responsible use of Generative AI in chemical engineering
in Digital Chemical Engineering
Daniel T
(2024)
Potential of Progressive and Disruptive Innovation-Driven Cost Reductions of Green Hydrogen Production.
in Energy & fuels : an American Chemical Society journal
Fisher O
(2024)
Responsive CO 2 capture: predictive multi-objective optimisation for managing intermittent flue gas and renewable energy supply
in Reaction Chemistry & Engineering
Liang X
(2025)
Automation-Assisted Systemic Kinetic Investigation on Alcohol Electrooxidations Coupled with Hydrogen Generation
in ECS Meeting Abstracts
Liang X
(2026)
Autonomous in silico optimization framework for high-performance micromixers
in Chemical Engineering Journal
Liang X
(2026)
An automated microfluidics platform for accelerating kinetics studies of alcohol electrooxidations
in Device
M Ojeda
Plastic Waste Valorisation into Hydrogen and Solid Carbon by Tandem Induction Catalytic System
in Energy Conversion and Management
Related Projects
| Project Reference | Relationship | Related To | Start | End | Award Value |
|---|---|---|---|---|---|
| EP/W018969/1 | 31/05/2022 | 30/08/2022 | £1,385,108 | ||
| EP/W018969/2 | Transfer | EP/W018969/1 | 31/08/2022 | 30/11/2025 | £1,361,350 |
| Description | We have developed a pioneering "Zero Carbon Loss" biomanufacturing system, tackling the carbon waste and emissions of traditional industrial chemical production. This innovation supports the UK's 2050 Net Zero target while maintaining global competitiveness. Our electrochemical system integrates carbon capture and utilization (CCU), ensuring carbon is reused rather than lost. We have also introduced real-time sustainability assessments and digital twin technology, allowing continuous optimization from the early stages of manufacturing. This breakthrough enables sustainable production across industries, including pharmaceuticals, plastics, textiles, and construction, reducing reliance on fossil fuels. |
| Exploitation Route | Our Zero Carbon Loss manufacturing technologies offer strong potential for IP commercialization and industrial collaboration. Innovations such as carbon capture-integrated processes, real-time sustainability assessments, and digital twin technology can be commercialized through patents, licensing, and spin-outs, enabling businesses to adopt sustainable manufacturing solutions. Industry partners in pharmaceuticals, chemicals, and materials can use these advancements to improve resource efficiency, reduce emissions, and meet net-zero goals. The project also paves the way for collaborative R&D, scale-up demonstrations, and investment opportunities, ensuring broad adoption. |
| Sectors | Chemicals |
| Title | Supplementary information files for "Autonomous in silico optimization framework for high-performance micromixers" |
| Description | Supplementary files for article "Autonomous in silico optimization framework for high-performance micromixers" Effective mixing at the microscale is essential for lab-on-a-chip systems, yet designing micromixers that achieve both high mixing efficiency and low pressure drop remains challenging and resource-intensive. Here, we introduce an autonomous in silico framework for designing obstacle-based micromixers through integrating 3D geometry generation, computational fluid dynamics (CFD) simulations and a multi-objective artificial intelli?gence optimization algorithm within a fully automated close-loop workflow. A constraint-aware NSGA-II variant is used, incorporating a repair operator to ensure design feasibility. Experimentally validated against hyper?spectral imaging-based mixing characterization and pressure-drop measurements, the framework eliminates manual trial-and-error workload and alleviates researchers from the tedious tasks of navigating across 3D modeling, CFD simulations, and optimization algorithms, reducing optimization time by 48% compared to the conventional simulation-assisted approach. By autonomously screening hundreds of designs, it identifies Pareto?optimal micromixers and generates an extensive database that supports inverse design and reveals the mixing structure-performance relationship, facilitating the establishment of general design guidelines. The framework is generally applicable to a wide range of passive micromixers. © The Author(s), CC BY 4.0 |
| Type Of Material | Database/Collection of data |
| Year Produced | 2026 |
| Provided To Others? | Yes |
| URL | https://repository.lboro.ac.uk/articles/dataset/Supplementary_information_files_for_Autonomous_in_si... |
| Description | "Hydrogen Mission", British Council and Department for Energy Security & Net Zero, Italy |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Professor John Andresen was an invited advisor at this meeting involving researchers, the British Council and DESNZ to stimulate thinking. |
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| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Manuel Ojeda attended the event to celebrate the benefits of collaboration in innovation projects with networking opportunities. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://web-eur.cvent.com/event/90bf4c60-7a57-4891-bc48-acc78322c5df/summary |
| Description | Coverage Green flight paths |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Coverage Green flight paths; BBC News, The Herald, Yahoo! News UK& Ireland, Scottish Business News, Wood Central, FurekAlert! and Mirage News (by Prof John Andresen) The Herald - 14/11/2024 Green flight paths 'could unlock sustainable aviation', Scots uni study suggests Yahoo! News UK & Ireland - 14/11/2024 Green flight paths could unlock sustainable aviation, new research suggests Scottish Business News - 14/11/24 Are green flight Paths the key to sustainable aviation? Wood Central - 14/11/24 Green flight paths could unlock sustainable aviation, new research suggests EurekAlert! - 14/11/2024 Green Flight Paths: Key to Sustainable Aviation? Mirage News - 14/11/2024 |
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| URL | https://www.designdevelopmenttoday.com/industries/aerospace/news/22926691/green-flight-paths-could-u... |
| Description | ECR Net Zero Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
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| Primary Audience | Policymakers/politicians |
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| Part Of Official Scheme? | No |
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| Primary Audience | Professional Practitioners |
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| Description | H2FC Supergen Hub final annual assembly - Moving Ah2ead with Hydrogen (MAwH) |
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| Primary Audience | Professional Practitioners |
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| URL | https://task42.ieabioenergy.com/ |
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| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | (2024) Meeting with North Sea Transition Authority (NSTA) (at Heriot Watt University, attended by Dr Manuel Ojeda) |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.nstauthority.co.uk/ |
| Description | Net Zero Conference (Dr Manuel Ojeda as advisor and organising committee) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
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| Primary Audience | Public/other audiences |
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| URL | https://www.rsc.org/events/detail/75026/chemistry-and-climate-change-perspectives-on-decarbonisation |
| Description | Scientific Gatherings II - Northern Power |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
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| Year(s) Of Engagement Activity | 2022 |
| URL | https://sruk.org.uk/ceru-events/scientific-gatherings-ii-northern-power/ |
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| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
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| Primary Audience | Public/other audiences |
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| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Showcased by Dr Manuel Ojeda and Professor Maroto-Valer. |
| Year(s) Of Engagement Activity | 2023 |
| Description | VIP visit to our HW laboratory from the head of the Delegation of the Government of Catalonia to the UK & Ireland, and Joanna Cherry MP |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Showcased by Dr Manuel Ojeda. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Visit Navantia UK to HW laboratory |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
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| Primary Audience | Industry/Business |
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| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
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| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.cdice.ac.uk/news/idric-constructing-your-leadership-potential-workshop-series/ |
