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Biomanufacturing with carbon capture and utilisation: A Zero Carbon Loss System

Lead Research Organisation: University of Surrey
Department Name: Chemical Engineering

Abstract

Nearly 140,000 industrial materials and chemicals are marketed worldwide. Most of them are made from fossil feedstocks with high CO2 emission embedded, and very low resources efficiency. To maintain the UK's global competitiveness, it is vital to identify sustainable alternatives for the manufacturing of these chemicals and materials.

Biomanufacturing, that utilises biological systems to produce commercially important biomaterials and biomolecules plays an important role in sustainable development, and has shown successful applications in manufacturing electronic components (e.g., bio-based flexible printed circuits), fine or specialty chemicals (e.g., bio-lubricants), building and construction (e.g., biocementation), consumer products (e.g., bio-based detergents), food (e.g., vitamin and amino acid fortification) and pharmaceuticals (e.g., vaccine production).

However, none of the current biomanufacturing routes has achieved zero carbon loss or emission. In fact, many bioprocesses (such as those involving fermentation) will emit large amounts of CO2. In a typical biomanufacturing, only 2/3 of the carbon resources flow ends up in final products, while the rest 1/3 are lost during the manufacturing process, in the form of CO2 emissions and residue wastes.

To address this challenge, the project will create the first-of-its-kind Zero Carbon Loss biomanufacturing system that will pave the way for the UK to reach the 2050 Net Zero target. This will be achieved by developing novel sustainable biomanufacturing of aromatics, heterocyclics and other lignocellulosics products with integrated carbon capture and utilization within the manufacturing process. These bio-based products, like building blocks of Lego, then will be used in different combinations to make various product such as pharmaceuticals, plastics, textile, composite materials, etc, with overall net zero carbon loss (emission and waste) throughout the manufacturing life cycle.

The technology innovation and resources optimisation of the BMCCU manufacturing route (WP1) will be guided by real-time system wide sustainability assessments (WP3), linked by an interoperable digital twin of the manufacturing process beyond the state of the art (WP2). It creates a new approach in which the lifecycle sustainability assessments will serve as an interactive decision-making tool fully embedded in the early-stage technology developments, rather than traditional retrospective assessment.

The project will contribute significantly to the UK's National Industrial Biotechnology Strategy, with a potential scope of £4.5 billion GVA, 63,000 jobs, and 2.5 billion tonnes of CO2 saving per year by 2030.

To achieve the vision, this proposal brings together a diverse multidisciplinary team from Loughborough University, Heriot-Watt University and Imperial College London, with world leading expertise in circular economy, intelligent manufacturing, industrial digitalisation and decarbonisation.

Publications

10 25 50

Related Projects

Project Reference Relationship Related To Start End Award Value
EP/W018969/1 31/05/2022 30/08/2022 £1,385,108
EP/W018969/2 Transfer EP/W018969/1 31/08/2022 30/11/2025 £1,361,350
 
Description We have developed a pioneering "Zero Carbon Loss" biomanufacturing system, tackling the carbon waste and emissions of traditional industrial chemical production. This innovation supports the UK's 2050 Net Zero target while maintaining global competitiveness.

Our electrochemical system integrates carbon capture and utilization (CCU), ensuring carbon is reused rather than lost. We have also introduced real-time sustainability assessments and digital twin technology, allowing continuous optimization from the early stages of manufacturing.

This breakthrough enables sustainable production across industries, including pharmaceuticals, plastics, textiles, and construction, reducing reliance on fossil fuels.
Exploitation Route Our Zero Carbon Loss manufacturing technologies offer strong potential for IP commercialization and industrial collaboration. Innovations such as carbon capture-integrated processes, real-time sustainability assessments, and digital twin technology can be commercialized through patents, licensing, and spin-outs, enabling businesses to adopt sustainable manufacturing solutions.

Industry partners in pharmaceuticals, chemicals, and materials can use these advancements to improve resource efficiency, reduce emissions, and meet net-zero goals. The project also paves the way for collaborative R&D, scale-up demonstrations, and investment opportunities, ensuring broad adoption.
Sectors Chemicals

 
Title Supplementary information files for "Autonomous in silico optimization framework for high-performance micromixers" 
Description Supplementary files for article "Autonomous in silico optimization framework for high-performance micromixers" Effective mixing at the microscale is essential for lab-on-a-chip systems, yet designing micromixers that achieve both high mixing efficiency and low pressure drop remains challenging and resource-intensive. Here, we introduce an autonomous in silico framework for designing obstacle-based micromixers through integrating 3D geometry generation, computational fluid dynamics (CFD) simulations and a multi-objective artificial intelli?gence optimization algorithm within a fully automated close-loop workflow. A constraint-aware NSGA-II variant is used, incorporating a repair operator to ensure design feasibility. Experimentally validated against hyper?spectral imaging-based mixing characterization and pressure-drop measurements, the framework eliminates manual trial-and-error workload and alleviates researchers from the tedious tasks of navigating across 3D modeling, CFD simulations, and optimization algorithms, reducing optimization time by 48% compared to the conventional simulation-assisted approach. By autonomously screening hundreds of designs, it identifies Pareto?optimal micromixers and generates an extensive database that supports inverse design and reveals the mixing structure-performance relationship, facilitating the establishment of general design guidelines. The framework is generally applicable to a wide range of passive micromixers. © The Author(s), CC BY 4.0 
Type Of Material Database/Collection of data 
Year Produced 2026 
Provided To Others? Yes  
URL https://repository.lboro.ac.uk/articles/dataset/Supplementary_information_files_for_Autonomous_in_si...
 
Description "Hydrogen Mission", British Council and Department for Energy Security & Net Zero, Italy 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Professor John Andresen was an invited advisor at this meeting involving researchers, the British Council and DESNZ to stimulate thinking.
Year(s) Of Engagement Activity 2023
 
Description Celebrating Collaborative Innovation in Hydrogen Technology Development 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Dr Manuel Ojeda attended the event to celebrate the benefits of collaboration in innovation projects with networking opportunities.
Year(s) Of Engagement Activity 2022
URL https://web-eur.cvent.com/event/90bf4c60-7a57-4891-bc48-acc78322c5df/summary
 
Description Coverage Green flight paths 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Coverage Green flight paths; BBC News, The Herald, Yahoo! News UK& Ireland, Scottish Business News, Wood Central, FurekAlert! and Mirage News (by Prof John Andresen)

The Herald - 14/11/2024
Green flight paths 'could unlock sustainable aviation', Scots uni study suggests
Yahoo! News UK & Ireland - 14/11/2024
Green flight paths could unlock sustainable aviation, new research suggests
Scottish Business News - 14/11/24
Are green flight Paths the key to sustainable aviation?
Wood Central - 14/11/24
Green flight paths could unlock sustainable aviation, new research suggests
EurekAlert! - 14/11/2024
Green Flight Paths: Key to Sustainable Aviation?
Mirage News - 14/11/2024
Year(s) Of Engagement Activity 2024
URL https://www.designdevelopmenttoday.com/industries/aerospace/news/22926691/green-flight-paths-could-u...
 
Description ECR Net Zero Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Dr Manuel Ojeda was an attendee, the meeting aimed to bring together early career researchers (ECRs) from across the net zero community. It included a mix of keynote speakers, parallel sessions (skills based and topic based) and a networking dinner.
Year(s) Of Engagement Activity 2022
URL https://www.cdice.ac.uk/events/ecr-net-zero-conference/
 
Description ETIP Bioenergy webinar: Bio CCS - Deployment Examples 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Dr Manuel Ojeda participated on webinar series at international level with more than 200 participants.
Year(s) Of Engagement Activity 2023
 
Description Engineering Net Zero conference 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Dr Manuel Ojeda was part of the organizing committed with invited speakers from government/policy makers, industry and academy including Professor Mercedes Maroto-Valer who was an invited speaker.
Year(s) Of Engagement Activity 2023
 
Description H2FC Supergen Hub final annual assembly - Moving Ah2ead with Hydrogen (MAwH) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The Moving AH2ead with Hydrogen programme of speakers is cross-sector and solutions focussed, aimed at sharing perspectives, overcoming barriers and Moving AH2ead with Hydrogen.
Year(s) Of Engagement Activity 2022
URL https://www.h2fcsupergen.com/clean-energy/moving-ahead-with-hydrogen-review/#:~:text=To%20mark%20the...
 
Description IEA TCP-Task42 Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Professor John Andresen is an advisor at this international platform for collaboration and information exchange between industry, SMEs, GOs, NGOs, RTOs and universities concerning biorefinery research, development, demonstration and policy analysis.
Year(s) Of Engagement Activity 2022
URL https://task42.ieabioenergy.com/
 
Description Meeting with North Sea Transition Authority (NSTA) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact (2024) Meeting with North Sea Transition Authority (NSTA) (at Heriot Watt University, attended by Dr Manuel Ojeda)
Year(s) Of Engagement Activity 2024
URL https://www.nstauthority.co.uk/
 
Description Net Zero Conference (Dr Manuel Ojeda as advisor and organising committee) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Net Zero Conference: (Dr Manuel Ojeda as advisor and organising committee) as part of the organising committee with invited speakers from government/policy makers, industry and academy. With local range (Edinburgh) and more than 150 participants.
Year(s) Of Engagement Activity 2024
 
Description Net Zero Industry" Visualisation Tool 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Net Zero Industry" Visualisation Tool (Dr Manuel Ojeda involved on the development)
Year(s) Of Engagement Activity 2024
URL https://idric.org/netzero-industry/#/home
 
Description RSC: Chemistry and Climate Change: Perspectives on Decarbonisation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Undergraduate students
Results and Impact Dr Manuel Ojeda was an attendee at this local workshop (Edinburgh) involving undergraduate students (more than 50), to explore decarbonisation and how chemistry plays an important role in both the production and reduction of carbon dioxide emissions.
Year(s) Of Engagement Activity 2022
URL https://www.rsc.org/events/detail/75026/chemistry-and-climate-change-perspectives-on-decarbonisation
 
Description Scientific Gatherings II - Northern Power 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Dr Manuel Ojeda as invited speaker, the conference provided networking from different disciplines and knowledge exchange.
Year(s) Of Engagement Activity 2022
URL https://sruk.org.uk/ceru-events/scientific-gatherings-ii-northern-power/
 
Description The Capital Hydrogen Programme 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Dr Manuel Ojeda participated in a webinar at national level (UK) with 100 attendants from general public and industry.
Year(s) Of Engagement Activity 2022
 
Description VIP visit to Heriot Watt laboraotyr from Irish Consu General and HWU Chief Scientist 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Policymakers/politicians
Results and Impact Showcased by Dr Manuel Ojeda and Professor Maroto-Valer.
Year(s) Of Engagement Activity 2023
 
Description VIP visit to our HW laboratory from the head of the Delegation of the Government of Catalonia to the UK & Ireland, and Joanna Cherry MP 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Policymakers/politicians
Results and Impact Showcased by Dr Manuel Ojeda.
Year(s) Of Engagement Activity 2024
 
Description Visit Navantia UK to HW laboratory 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Industry/Business
Results and Impact Navantia UK visit to HW laboratories including a showcase about the project.
Year(s) Of Engagement Activity 2024
 
Description Workshop: Constructing Your Leadership Potential Workshop 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Workshop: Constructing Your Leadership Potential Workshop (attended by Dr Manuel Ojeda)
Year(s) Of Engagement Activity 2024
URL https://www.cdice.ac.uk/news/idric-constructing-your-leadership-potential-workshop-series/