500 MHz NMR Spectrometer to Support Organic, Bio-organic and Inorganic Chemistry
Lead Research Organisation:
University of Bath
Department Name: Chemistry
Abstract
NMR spectroscopy is a key tool in the elucidation of chemical structure. A new NMR spectrometer operating at higher field (500 MHz) than currently available is required by a group of synthetic chemists interested in organic, bio-organic and inorganic chemistry. This spectrometer will facilitate new research areas in the Department of Chemistry at Bath by providing access to NMR facilities with (a) high sensitivity (somewhere in the region of a 40% increase over our current 400 MHz NMR spectrometer will be provided), (b) greater resolution that will allow resonances from more complex molecules to be separated out and (c) new hardware (for example, lower frequency nuclei can be studied, while an inverse detection probe will give higher proton sensitivity, allowing compounds only available in very small amounts to be characterised and and their structures established). Specific areas that will be enabled include the synthesis of chiral molecules, modification of peptides and proteins and the development of new catalysts.
Organisations
Publications
Segarra C
(2012)
Ring-Expanded N-Heterocyclic Carbene Complexes of Rhodium with Bifluoride, Fluoride, and Fluoroaryl Ligands
in Organometallics
Schwartsburd L
(2014)
Mechanistic Studies of the Rhodium NHC Catalyzed Hydrodefluorination of Polyfluorotoluenes
in Organometallics
Poulten RC
(2014)
Stereoelectronic effects in C-H bond oxidation reactions of Ni(I) N-heterocyclic carbene complexes.
in Inorganic chemistry
Poulten RC
(2013)
Synthesis, electronic structure, and magnetism of [Ni(6-Mes)2]+: a two-coordinate nickel(I) complex stabilized by bulky N-heterocyclic carbenes.
in Journal of the American Chemical Society
Page MJ
(2011)
Formation and reactivity of the cyclometallated N-heterocyclic carbene complexes [Ru(NHC)'(dppe)(CO)H].
in Dalton transactions (Cambridge, England : 2003)
Page MJ
(2013)
Three-coordinate nickel(I) complexes stabilised by six-, seven- and eight-membered ring n-heterocyclic carbenes: synthesis, EPR/DFT studies and catalytic activity.
in Chemistry (Weinheim an der Bergstrasse, Germany)
L. Häller L
(2009)
Formation of [Ru(NHC) 4 (? 2 -O 2 )H] + : An Unusual, High Frequency Hydride Chemical Shift and Facile, Reversible Coordination of O 2
in Journal of the American Chemical Society
Häller LJ
(2010)
Experimental and computational investigation of C-N bond activation in ruthenium N-heterocyclic carbene complexes.
in Journal of the American Chemical Society
Description | Range of projects covered by the instrument ranging from inorganic, organic, materials, pharmaceuticals and bilogical chemistry. |
Exploitation Route | Follow on funding as well as citations of the results by other acdemics in the literature. |
Sectors | Chemicals |
Description | Findings from research instrumentation have been used in both academic and industrial environments. Multi-user instrument so PI does not have exact details for each user. |
First Year Of Impact | 2006 |
Sector | Chemicals |
Impact Types | Societal |