Physical Organic Chemistry: Opportunities in Synthesis, Materials and Pharmaceuticals
Lead Research Organisation:
University of Strathclyde
Department Name: Pure and Applied Chemistry
Abstract
This application aims to catalyse and sustain a new dimension in UK research capability in physical organic chemistry. Our strategic alliance in physical organic chemistry will provide a unique continuum of expertise to tackle research opportunities in areas as diverse as materials chemistry, synthesis methodologies and pharmaceutical discovery and development. It will have the capability to address issues from solid-state to solution and gas-phase, from small molecules to biopolymers, and from nanoscale to pilot plant. We focus on topics of international significance to industry worldwide as well as to academic chemistry, that will help to (i) drive the creation of 21st-century electronic materials, devices and technologies (ii) understand and exploit methodologies for assisting chemical reactions with the potential to revolutionise energy use in chemicals and pharmaceuticals industries (iii) provide new and more effective medicines through understanding molecular recognition in pharmaceutical systems including drug-receptor, drug-drug and drug-carrier complexes. Its importance is underlined by the initial substantial support from diverse sectors of the chemicals and pharmaceuticals industry that we have so far put in place. It will initially lead to 26 new appointments, and we look forward to even more dynamic growth as the program unfolds.
Organisations
- University of Strathclyde (Lead Research Organisation, Project Partner)
- Novartis (Collaboration)
- MERCK (Collaboration)
- AstraZeneca (United Kingdom) (Collaboration, Project Partner)
- Rigaku (Collaboration)
- UNIVERSITY OF GLASGOW (Collaboration)
- Xstalbio Limited (Collaboration)
- GlaxoSmithKline (GSK) (Collaboration)
- Organon laboratories ltd (Collaboration)
- CEM Corporation (Collaboration)
- GlaxoSmithKline R & D Ltd (Project Partner)
- University of Glasgow (Project Partner)
- CEM Microwave Technology Ltd (Project Partner)
- Rigaku (United Kingdom) (Project Partner)
- XstalBio (Project Partner)
- Scottish Funding Council (Project Partner)
- Bruker Biospin Ltd (Project Partner)
- Merck Speciality Chemicals Ltd (Project Partner)
- Organon Research Scotland (Project Partner)
- LOT Oriel Ltd (Project Partner)
Publications
Jones AO
(2012)
Temperature dependent solid-state proton migration in dimethylurea-oxalic acid complexes.
in Physical chemistry chemical physics : PCCP
Jolly PI
(2012)
Reactions of triflate esters and triflamides with an organic neutral super-electron-donor.
in Organic & biomolecular chemistry
Jolly P
(2012)
Imidazole-derived carbenes and their elusive tetraazafulvalene dimers
in Chemical Science
Johnston A
(2008)
Cytenamide-formic acid (1/1).
in Acta crystallographica. Section E, Structure reports online
Johnston A
(2008)
Cytenamide trifluoro-acetic acid solvate.
in Acta crystallographica. Section E, Structure reports online
Johnston A
(2011)
Experimental and Predicted Crystal Energy Landscapes of Chlorothiazide
in Crystal Growth & Design
Johnston A
(2008)
Cytenamide-1,4-dioxane (2/1).
in Acta crystallographica. Section E, Structure reports online
Johnston A
(2008)
Targeted crystallisation of novel carbamazepine solvates based on a retrospective Random Forest classification
in CrystEngComm
Johnston A
(2008)
Cytenamide acetic acid solvate.
in Acta crystallographica. Section E, Structure reports online
Johnston A
(2008)
Cytenamide-butyric acid (1/1).
in Acta crystallographica. Section E, Structure reports online
| Description | This grant has provided a framework for development of many facets of physical organic chemistry, from advanced materials to reactions mechanisms to breakthroughs in crystallisation and manufacture. The award (EP/E036244/1, Physical Organic Chemistry: Opportunities in Synthesis, Materials and Pharmaceuticals) has contributed to a number of substantial follow on activities. The strong focus on crystallisation and investments in single crystal diffraction contributed to the strengths that underpinned the development of CMAC as a collaborative manufacturing research centre for continuous crystallisation and processing of pharmaceuticals, co-created with GSK, AZ and Novartis. Glasgow University have been collaborators on the subsequent critical mass awards that include: EP/I033459/1, EPSRC Centre for Innovative Manufacturing for Continuous Manufacturing and Crystallisation; EP/K503289/1, Doctoral Training Centre in Continuous Manufacturing and Crystallisation and EP/P006965/1, Future Continuous Manufacturing and Advanced Crystallisation Research Hub. Moreover, the early career researchers appointed into SIPBS have been able to utilise the equipment base to accelerate their career, for example, Dr Iain Oswald secured an EPSRC early career manufacturing fellowship EP/N015401/1, Pressure-Induced Nucleation for the Continuous Manufacture of supramolecular assemblies. In addition we have secured additional investments to augment our capabilities in surface analysis of pharmaceutical systems via EPSRC and Wolfson Foundation awards for fast-scan AFM and ToF-SIMS. It also led to the Prosperity Partnership with GSK and the University of Nottingham that starts in 2019. It provided training for many early career researchers and particularly to the appointment of at least one additional academic, Dr. David Nelson, recently promoted to Senior Lecturer, and more than 26 PhD students at the University of Strathclyde, notably co-funded by GSK and the University of Strathclyde, engaged in physical organic chemistry. A key example of international success in this follow-up is Joshua Barham, who won the world championship of chemistry PhDs, namely the Reaxys Prize, in 2017 for his studies on site-selective late-stage functionalisation of complex moleculs of biological interest. Joshua is the first such winner to be associated with a Scottish University.[https://www.elsevier.com/solutions/reaxys/reaxys-phd-prize]. It is clear that this award has been the springboard for a number of important interactions between UK chemistry and pharmacy and the pharmaceutical industry. Through it, we compete at a higher international level. |
| Exploitation Route | The findings are being taken forward in collaborations with pharmaceutical companies for clean manufacturing processes. |
| Sectors | Chemicals,Pharmaceuticals and Medical Biotechnology |
| URL | http://www.johnmurphygroup.com/research-interests.html |
| Description | The summary below includes impacts on academic and non-academic spheres. Our Physical Organic Chemistry (POC) grant had three streams and so the following commentary follows similar lines. Impacts have been numerous, building on the POC award, extending to wider applications of diffraction to support structural investigations of organic pharmaceutical solids. These include investigations of novel molecular solids with international groups (Nature Materials volume 20, pages403-409 (2021); Mechanistic insights of evaporation-induced actuation in supramolecular crystals | Nature Materials). International impact is seen via Dr Andrew Urquhart who was employed under the award has taken up an academic post in Denmark and is Associate Professor in the Dept of Health Technology at the Technical University of Denmark (DTU). However, other technical areas of interest established under the POC on surface analysis have continued to thrive yielding high impact multidisciplinary scientific papers (e.g. Nature Chemistry volume 12, pages 914-920 (2020); Olanzapine crystal symmetry originates in preformed centrosymmetric solute dimers | Nature Chemistry). We have continued to successfully build our pharmaceutical materials theme with strategic equipment funding from EPSRC looking at compaction simulation for crystalline and amorphous systems (EP/S02168X/1; 2019-22; PI: Florence, Strathclyde) and novel in line flow measurements of particle formation processes (EP/T006331/1; 2020-2023, PI Prof Meldrum, Leeds University). Also new international collaborations have been developed expemplified with the recent EPSRC International Centre to Centre award to CMAC at Strathclyde for the Digital Design and Manufacture of Amorphous Pharmaceuticals with University of Copenhagen in Denmark and TU Ghent in Belgium (EP/W003295/1; 2022-25; PI Florence). These projects have attracted industry partners including GSK, AstraZeneca (AZ), Lek Pharmaceuticals and CCDC. Our work on scattering studies of molecular solid structures from the POC has extended to amorphous systems and recent award of a KTP with AZ to implement PDF measurement in their internal development pipelines highlights the industrial relevance and ongoing translation of our early research into industrial practice is actively continuing and will lead to further impact in the coming years. The NMR and microwave equipment that was contributed through this award allowed physical organic chemistry to flourish and the equipment helped to train many highly successful PhD students. One example is Dr. Franziska Schoenebeck, now Professor at RWTH University, who is Associate Editor of Journal of the American Chemical Society and a leading international light in experimental and computational mechanistic chemistry. Another example is David Nelson, who completed his PhD here in POC and in 2014 was appointed as a Chancellors Fellow in Strathclyde. He has since been promoted to Senior Lecturer and is a highly active member of the POC community internationally, both for his own research and for his international collaborations, notably in Spain. The grant also led to international collaborations, e.g. between Prof Murphy and Prof Chiba (NTU, Singapore) which was supported by funding from The Royal Society and oversaw exchanges of PhD students between Singapore and Strathclyde. The POC grant also has led to ongoing international recognition of our role in POC. Thus, this year, 2022, Prof Murphy will be a Plenary Speaker at the Reaction Mechanisms Conference, Boulder, Colorado, and Keynote Speaker at the 25th International Conference on Physical Organic Chemistry (ICPOC-25) in Hiroshima, Japan as well as Invited Speaker at the Pacific Symposium on Radical Chrmistry (PSRC-12, Kyoto, Japan) (now postponed until 2023). High impact papers on POC and mechanistic themes are developing high citation numbers e.g. J. Am. Chem. Soc., 2016, 138, 7402-7410. In industry, our successes in POC were influential in the development of (i) the ongoing GSK-SU joint PhD programme (led in SU by Prof Kerr) which has been outstandingly successful in providing very large numbers of PhD students for UK plc and also (ii) the ongoing EPSRC co-funded Prosperity Partnership between GSK, University of Strathclyde and University of Nottigham EP/S035990/1 'Accelerated Discovery and Development of New Medicines: Prosperity Partnership for a Healthier Nation' The Glasgow University component of the POC award led to the appointment of Dr Goetz Bucher (https://www.gla.ac.uk/schools/chemistry/staff/goetzbucher/) and the purchase of equipment (e.g EPR and high end UV-vis-NIR and fluorescence spectrometers). Following the completion of the grant, Physical Organic Chemistry remains a strong and flourishing sub-discipline within the School as indicated by our more recent appointments (Professor Peter Skabara, Professor Dave Adams). Researchers in post prior to the award (Professor Graeme Cooke, Professor Richard Hartley) have benefited significantly from the equipment associated with this grant. Furthermore, the excellent equipment base the grant provided has allowed the School to appointment of Dr Stephen Sproules (EPR specialist) and Dr William Peveler (fluorescence sensing). |
| First Year Of Impact | 2014 |
| Sector | Chemicals,Healthcare |
| Description | Accelerated Discovery and Development of New Medicines: Prosperity Partnership for a Healthier Nation |
| Amount | £5,495,023 (GBP) |
| Funding ID | EP/S035990/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2019 |
| End | 12/2023 |
| Description | Doctoral Training Centre in Continuous Manufacturing and Crystallisation |
| Amount | £4,348,959 (GBP) |
| Funding ID | EP/K503289/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2012 |
| End | 06/2019 |
| Description | EPSRC Centre for Innovative Manufacturing for Continuous Manufacturing and Crystallisation |
| Amount | £6,060,701 (GBP) |
| Funding ID | EP/H024107/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2011 |
| End | 12/2016 |
| Description | Future Continuous Manufacturing and Advanced Crystallisation Research Hub |
| Amount | £10,330,544 (GBP) |
| Funding ID | EP/P006965/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 12/2023 |
| Description | Pressure-Induced Nucleation for the Continuous Manufacture of supramolecular assemblies |
| Amount | £966,179 (GBP) |
| Funding ID | EP/N015401/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2016 |
| End | 05/2021 |
| Title | An investigation of the role increasing p-conjugation has on the efficiency of dye-sensitized solar cells fabricated from ferrocene-based dyes |
| Description | Data underpinning the electrochemical data in the linked publication. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Title | Convenient synthesis of EDOT-based dyes by CH-activation and their application as dyes in dye-sensitized solar cells |
| Description | Supporting data of materials characterisation and solar cells characterisation. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Title | Donor-free oligothiophene based dyes with di-anchor architecture for Dye-Sensitized Solar Cells |
| Description | |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | Yes |
| URL | http://researchdata.gla.ac.uk/id/eprint/1128 |
| Title | New BODIPY derivatives with near infra-red absorption as small molecule donors for bulk heterojunction solar cells |
| Description | |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Title | Redox-mediated reactions of vinylferrocene: toward redox auxiliaries |
| Description | DFT Modelling data |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Description | Accelerated Discovery and Development of New Medicines: Prosperity Partnership for a Healthier Nation |
| Organisation | GlaxoSmithKline (GSK) |
| Country | Global |
| Sector | Private |
| PI Contribution | I am leader for one of 5 themes; and am a member of a second theme. I represented University of Strathclyde as party of the panel of 3 who were interviewed at EPSRC for this grant |
| Collaborator Contribution | GSK are the lead industrial partners who are collaborating with the University of Strathclyde and theUniversity of Nottingham in this Prosperity Partnership, which addresses accelerated discovery and development of new medicines. |
| Impact | The collaboration has just started, so,as yet, there are no outputs, but they will be reported under that collaborative grant to RCUK. |
| Start Year | 2019 |
| Description | Invited Table Rond Presentations and Discussions |
| Organisation | Novartis |
| Country | Global |
| Sector | Private |
| PI Contribution | Participant : Participation in workshop/networks with non-academic organisation : Invited by Novartis in Basel to present a lecture on my recent chemistry and to engage in discussions about their potential interest in our chemistry |
| Collaborator Contribution | The Partners set up the meeting in Basel which I attended. The discussions that followed di not progress to a more substantive collaboration |
| Impact | These discussions did not lead to longer term collaboration |
| Start Year | 2012 |
| Description | Joint research with UNIVERSITY OF GLASGOW |
| Organisation | University of Glasgow |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | University of Strathclyde researchers worked on this project with researchers from UNIVERSITY OF GLASGOW |
| Start Year | 2007 |
| Description | Knowledge Transfer secondment |
| Organisation | GlaxoSmithKline (GSK) |
| Department | Research and Development GSK |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Advisor : Joint or sponsored appointments or secondments with industry or commerce : One of my research group, Phillip Jolly, undertook a placement in GSK followed by a period back in U Strathclyde to facilitate interchange of our expertise with GSK |
| Collaborator Contribution | The collaborators hosted my team member Dr Phillip Jolly for a placement in 2011 |
| Impact | This collaboration strengthened the c.v. of Dr Phillip Jolly, who has pursued his career in chemical research and is now in Canada |
| Start Year | 2011 |
| Description | Project partnership with Astra Zeneca |
| Organisation | AstraZeneca |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Astra Zeneca worked with the research team and assisted/contributed to the project outcomes |
| Collaborator Contribution | AstraZeneca contributed studentship funding |
| Impact | Hybrid super electron donors - preparation and reactivity By: Garnier, Jean; Thomson, Douglas W.; Zhou, Shengze; et al. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY Volume: 8 Published: JUL 3 2012 Imidazole-derived carbenes and their elusive tetraazafulvalene dimers By: Jolly, Phillip I.; Zhou, Shengze; Thomson, Douglas W.; et al. CHEMICAL SCIENCE Volume: 3 Issue: 5 Pages: 1675-1679 Published: 2012 Structure and reactivity in neutral organic electron donors derived from 4-dimethylaminopyridine By: Garnier, Jean; Kennedy, Alan R.; Berlouis, Leonard E. A.; et al. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY Volume: 6 Article Number: 73 Published: JUL 5 2010 Electron transfer activity of a cobalt crown carbene complex By: Park, Stuart R.; Findlay, Neil J.; Garnier, Jean; et al. TETRAHEDRON Volume: 65 Issue: 52 Pages: 10756-10761 Published: DEC 26 2009 One-Carbon Extrusion from a Tetraazafulvalene. Isolation of Aldehydes and a Study of Their Origin By: Murphy, John A.; Schoenebeck, Franziska; Findlay, Neil J.; et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 131 Issue: 18 Pages: 6475-6479 Published: MAY 13 2009 One-pot reduction of aryl iodides using 4-DMAP methiodide salt By: Garnier, Jean; Murphy, John A.; Zhou, Sheng-Ze; et al. SYNLETT Issue: 14 Pages: 2127-2131 Published: AUG 22 2008 Super-electron donors: Bis-pyridinylidene formation by base treatment of pyridinium salts By: Murphy, John A.; Garnier, Jean; Park, Stuart R.; et al. ORGANIC LETTERS Volume: 10 Issue: 6 Pages: 1227-1230 Published: MAR 20 2008 |
| Start Year | 2007 |
| Description | Project partnership with CEM Microwave Technology Ltd |
| Organisation | CEM Corporation |
| Country | United States |
| Sector | Public |
| PI Contribution | CEM Microwave Technology Ltd worked with the research team and assisted/contributed to the project outcomes |
| Collaborator Contribution | CEM contributed sompetitive servicing of microwave equipment |
| Impact | n/a |
| Start Year | 2007 |
| Description | Project partnership with Glaxo Smithkline (UK) |
| Organisation | GlaxoSmithKline (GSK) |
| Country | Global |
| Sector | Private |
| PI Contribution | Glaxo Smithkline (UK) worked with the research team and assisted/contributed to the project outcomes |
| Collaborator Contribution | GSK contributed to funding of PhD studentships |
| Impact | Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C-H Functionalization of Trialkylamine N-CH3 Groups By: Barham, Joshua P.; John, Matthew P.; Murphy, John A. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 138 Issue: 47 Pages: 15482-15487 Published: NOV 30 2016 Mechanistic investigations of the Chan-Evans-Lam reaction: Overcoming the BPin problem By: Vantourout, Julien; Sproules, Stephen; Isidro-Llobet, Albert; et al. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Volume: 252 Meeting Abstract: 389 Published: AUG 20 2016 Clinical progress and pharmacology of small molecule bromodomain inhibitors By: Theodoulou, Natalie H.; Tomkinson, Nicholas C. O.; Prinjha, Rab K.; et al. CURRENT OPINION IN CHEMICAL BIOLOGY Volume: 33 Pages: 58-66 Published: AUG 2016 KOtBu: A Privileged Reagent for Electron Transfer Reactions? By: Barham, Joshua P.; Coulthard, Graeme; Emery, Katie J.; et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 138 Issue: 23 Pages: 7402-7410 Published: JUN 15 2016 Double Deprotonation of Pyridinols Generates Potent Organic Electron-Donor Initiators for Haloarene-Arene Coupling By: Barham, Joshua P.; Coulthard, Graeme; Kane, Ryan G.; et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Volume: 55 Issue: 14 Pages: 4492-4496 Published: MAR 24 2016 Context Sensitive Links Future Supply Chains Enabled by Continuous Processing-Opportunities Challenges May 20-21 2014 Continuous Manufacturing Symposium. By: Srai, Jagjit Singh; Badman, Clive; Krumme, Markus; et al. Journal of pharmaceutical sciences Volume: 104 Issue: 3 Pages: 840-849 Published: 2015-Mar (Epub 2016 Jan 08) One-pot functionalisation of N-substituted tetrahydro-isoquinolines by photooxidation and tunable organometallic trapping of iminium intermediates By: Barham, Joshua P.; John, Matthew P.; Murphy, John A. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY Volume: 10 Pages: 2981-2988 Published: DEC 12 2014 Lead identification of benzimidazolone and, azabenzimidazolone arylsulfonamides as CC-chemokine receptor 4 (CCR4) antagonists By: Miah, Afjal H.; Abas, Hossay; Begg, Malcolm; et al. BIOORGANIC & MEDICINAL CHEMISTRY Volume: 22 Issue: 15 Pages: 4298-4311 Published: AUG 1 2014 |
| Start Year | 2007 |
| Description | Project partnership with Merck Chemicals Ltd |
| Organisation | Merck |
| Department | Merck UK |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Merck Chemicals Ltd worked with the research team and assisted/contributed to the project outcomes |
| Collaborator Contribution | Merck Chemicals Ltd contriobuted to funding of equipment |
| Impact | n/a |
| Start Year | 2007 |
| Description | Project partnership with Organon Laboratories Ltd |
| Organisation | Organon Laboratories Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Organon Laboratories Ltd worked with the research team and assisted/contributed to the project outcomes |
| Collaborator Contribution | Organon contributed funding for a PhD studentship |
| Impact | Development of chiral heteroleptic magnesium amides; asymmetric deprotonations mediated by six-membered metallocyclic amidomagnesium naphtholates By: Carswell, Emma L.; Kerr, William J.; McArthur, Duncan; et al. TETRAHEDRON Volume: 70 Issue: 40 Special Issue: SI Pages: 7344-7349 Published: OCT 7 2014 Recyclable supported chiral amines for use within highly efficient asymmetric Mg-amide base processes By: Kerr, William J.; Pazicky, Marek; McArthur, Duncan Conference: 236th National Meeting of the American-Chemical-Society Location: Philadelphia, PA Date: AUG 17-21, 2008 Sponsor(s): Amer Chem Soc ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Volume: 236 Meeting Abstract: 45-ORGN Published: AUG 17 2008 |
| Start Year | 2007 |
| Description | Project partnership with Rigaku |
| Organisation | Rigaku |
| Country | Japan |
| Sector | Private |
| PI Contribution | Rigaku worked with the research team and assisted/contributed to the project outcomes |
| Collaborator Contribution | Rigaku contributed to the equipment used in this programme |
| Impact | n/a |
| Start Year | 2007 |
| Description | Project partnership with University of Glasgow |
| Organisation | University of Glasgow |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | University of Glasgow worked with the research team as part of the WestCHEM collaboration |
| Collaborator Contribution | hosting of joint meetings, exchange of reseachers and joint use of equipment |
| Impact | N/A |
| Start Year | 2007 |
| Description | Project partnership with Xstalbio Limited |
| Organisation | Xstalbio Limited |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Xstalbio Limited worked with the research team and assisted/contributed to the project outcomes |
| Collaborator Contribution | Xstalbio Limited contributed to PhD studentship funding |
| Impact | N/A |
| Start Year | 2007 |
| Description | 2 Lectures at Univrsite de Bordeaux |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | 2 Lectures at Universite de Bordeaux, principally to a postgraduate audience, on the discoveries arising from our research |
| Year(s) Of Engagement Activity | 2017 |
| Description | 2 Research Colloquia at U Regensburg |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Graduate Research Training Group in Photocatalysis, U Regensburg, Germany |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited Table Rond Presentations and Discussions |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited by Novartis in Basel to present a lecture on my recent chemistry and to engage in discussions about their potential interest in our chemistry. Not recorded |
| Year(s) Of Engagement Activity | 2012 |
| Description | Lecture at Ecole Polytechnique |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture at Ecole polytechnique, principally to a postgraduate audience, on the discoveries arising from our research |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lecture at U de Grenoble |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture at Universite de Grenoble, principally to a postgraduate audience, on the discoveries arising from our research |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lecture at U. Paris 6 (Diderot) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture at Universite Paris 6 (Diderot), principally to a postgraduate audience, on the discoveries arising from our research |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lecture at Univeriste Pierre et Marie Curie, Paris |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture to postgraduate students, other researchers and prfoessional chemists on our research in electron transfer |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lecture at Universite de Montpellier |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture at Universite de Montpellier, principally to a postgraduate audience, on the discoveries arising from our research |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lecture at Universite de Mulhouse |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture at Universite de Mulhouse, principally to a postgraduate audience, on the discoveries arising from our research |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lecture at Universitet Uppsala |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture at Universitet Uppsala, Sweden, principally to a postgraduate audience, on the discoveries arising from our research |
| Year(s) Of Engagement Activity | 2017 |
| Description | Research Colloquium Imperial College, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | 'Lecture to young chemists', Imperial College London |
| Year(s) Of Engagement Activity | 2017 |
| Description | Research Colloquium University of Poitiers |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Visitor : Invited talk : Departmental Research colloquium. University of Poitiers this visit and lecture led to application for joint funding at Royal Society with Prof Sebastien Thibaudeau |
| Year(s) Of Engagement Activity | 2017 |
| Description | Research Colloquium University of Sussex |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Visitor : Invited talk : Departmental Research colloquium. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Research Colloquium at U Southampton |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Contributor : Invited talk : U Spouthampton |
| Year(s) Of Engagement Activity | 2013 |