Membrane Biophysics Platform
Lead Research Organisation:
Imperial College London
Department Name: Chemistry
Abstract
The proposed Platform grant renewal is aimed at giving us the ability to capitalise upon our position as a world leading group in membrane biophysics and self-assembled amphiphilic materials, and to promote and facilitate collaborations within the currently fragmented membrane biophysics community in the UK. To achieve these aims we will form collaborative research networks with groups having complementary expertise, and encourage interconnections between external groups via a combination of 'Ideas Workshops' and IT platforms. These networks will focus upon tackling key challenges at the Life Sciences Interface requiring multi-disciplinary approaches. We will support targeted short-term personnel exchange with a view to effecting knowledge transfer, proof-of-concept experiments and research training. Within this framework we will invite key collaborators as academic visitors and to present seminar series within our Department. We also wish to continue to facilitate exploitation of our specialised facilities by the wider research community.In addition to building upon the successes of our original objectives by studying the phase behaviour of novel amphiphiles and complex lipid mixtures, and the development of millisecond and microsceond pressure-jump synchrotron X-ray studies of lyotropic transitions, we also plan to develop the following areas of research within the renewed Platform grant, which we have identified as timely and important challenges at the Life/Physical Sciences interface:i) Understanding Membrane Asymmetry;ii) Protein Control of Lipid Membrane Morphology;iv) Regulation of Lipid Biosynthetic Pathways.iv) Lipid Mesophase Engineering Rules for Biomedical Imaging Applications.
Organisations
- Imperial College London (Lead Research Organisation)
- University of Manchester (Collaboration)
- University of Malaya (Collaboration)
- UNIVERSITY OF NOTTINGHAM (Collaboration)
- Unilever (Netherlands) (Collaboration)
- ETH Zurich (Collaboration)
- Polytechnic University of Valencia (Collaboration)
- Shiraz University of Technology (Collaboration)
- University Paris Sud (Collaboration)
- University of Warwick (Collaboration)
- DIAMOND LIGHT SOURCE (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- Commonwealth Scientific and Industrial Research Organisation (Collaboration)
- European Synchrotron Radiation Facility (Collaboration)
- Cancer Research UK (Collaboration)
- UNIVERSITY OF OXFORD (Collaboration)
- Max Planck Society (Collaboration)
- UNIVERSITY OF ABERDEEN (Collaboration)
- TU Dortmund University (Collaboration)
- Rutherford Appleton Laboratory (Collaboration)
- Institute of Cancer Research UK (Collaboration)
- University of Bristol (Collaboration)
- KING'S COLLEGE LONDON (Collaboration)
- UNIVERSITY OF SOUTHAMPTON (Collaboration)
Publications
McDonald C
(2017)
Structure and function of PspA and Vipp1 N-terminal peptides: Insights into the membrane stress sensing and mitigation.
in Biochimica et biophysica acta. Biomembranes
Miller D
(2013)
Protocell design through modular compartmentalization.
in Journal of the Royal Society, Interface
Miller DM
(2016)
Light-activated control of protein channel assembly mediated by membrane mechanics.
in Nanotechnology
Mohammad-Aghaie D
(2010)
Molecular dynamics simulations of liquid condensed to liquid expanded transitions in DPPC monolayers.
in The journal of physical chemistry. B
Mulet X
(2009)
Spatial localization of PtdInsP2 in phase-separated giant unilamellar vesicles with a fluorescent PLC-delta 1 PH domain.
in Methods in molecular biology (Clifton, N.J.)
Munhoz T
(2010)
Setting of commercial glass ionomer cement Fuji IX by (27)Al and (19)F MAS-NMR.
in Journal of dentistry
Niu XZ
(2009)
Droplet-based compartmentalization of chemically separated components in two-dimensional separations.
in Chemical communications (Cambridge, England)
O'Donnell M
(2009)
Raman spectroscopy, 19F and 31P MAS-NMR of a series of fluorochloroapatites
in Journal of the European Ceramic Society
O'Donnell M
(2010)
Real time neutron diffraction and solid state NMR of high strength apatite-mullite glass ceramic
in Journal of Non-Crystalline Solids
| Description | A selection of Key Findings from our Platform grant is as follows: a) We have demonstrated that lipid membranes can act as information pathways between proteins, without the need for direct protein-protein contact; b) We have found that lipid membrane curvature is induced by distearoyl phosphatidylinositol 4-phosphate; c) We have characterised the pressure - temperature phase behaviour of natural sphingomyelin extracts, and found evidence for non-lamellar phases; d) We have characterised the thermotropic and lyotropic liquid crystalline phase behaviour of a novel series of Guerbet branched-chain ß-D-glucosides, and have found that they form a variety of inverse cubic and inverse hexagonal phases; e) We discovered a novel lyotropic two-dimensional inverse ribbon phase in a branched-chain polyoxyethylene surfactant system, and demonstrated an unusual effect of hydrostatic pressure on the lattice parameters, with one increasing, and the other decreasing, with increasing pressure; f) We showed that we can produce ordered nanostructured amphiphile self-assembly materials from nonionic unsaturated monoethanolamide lipids in water; g) We studied the effect of hydrostatic pressure effects on the inverse micellar Fd3m cubic phase formed by a binary lipid mixture, and found that the lattice parameter is independent of pressure, but above a threshold pressure the lipids separate into two different liquid crystal phases; h) We developed a quantitative model for the kinetics of lyotropic phase transitions involving changes in monolayer curvature; i) We showed that certain aqueous buffers may adversely affect the phase behaviour of model lipid membranes; j) We have a developed a new model for how cationic drugs can interact with lipid membranes; k) We carried out molecular dynamics simulations of liquid condensed to liquid expanded transitions in DPPC monolayers; l) We observed the formation of an inverse hexagonal phase in DNA Lipoplexes by molecular dynamics simulations; m) We developed a microfluidic approach for high-throughput droplet interface bilayer (DIB) formation; n) We developed a microfluidic antibody capture chip with TIRF detection as a first step towards practical single cell proteomics. |
| Exploitation Route | Researchers in the fields of membrane biophysics and soft matter self-assembly can learn guiding principles from our work, and industrial scientists in the healthcare, pharma and personal products sectors can use our findings in the development of novel formulations. |
| Sectors | Agriculture, Food and Drink,Chemicals,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
| Description | Consultancy: Lipids & Membrane Biophysics, 161 Journal Issue. Discussion summary and research papers, in physical chemistry, chemical physics and biophysical chemistry. Grant: Contributions to Industry/NHS etc through Teaching/Training £2.5M Marie Curie Innovative Doctoral Programme (IDP) in collaboration with Syngenta (13 three year PhD studentships). Invited Article: RSC Journal Analyst-Special Issue Invitation to submit article to special issue of the RSC Jourmal Analyst entitled Emerging Investigators. Its a themed issue "to highlight some of the outstanding young analytical scientists of today". Invited Article: SDM Droplet Part III Invitation to submit paper to 10th anniversary edition of "Lab On the Chip". |
| First Year Of Impact | 2009 |
| Sector | Chemicals,Healthcare,Pharmaceuticals and Medical Biotechnology |
| Impact Types | Cultural |
| Description | Artificial hair constructs (Proctor and Gamble) |
| Amount | £85,000 (GBP) |
| Organisation | Procter & Gamble |
| Sector | Private |
| Country | United States |
| Start | |
| Description | Artificial hair constructs (Proctor and Gamble) |
| Amount | £85,000 (GBP) |
| Organisation | Procter & Gamble |
| Sector | Private |
| Country | United States |
| Start | |
| Description | Beamtime award SC2800, 3 days, Composition effects on a novel 3-D hexagonal lyotropic lipid phase and its phase transitions |
| Amount | £30,000 (GBP) |
| Organisation | European Synchrotron Radiation Facility |
| Sector | Charity/Non Profit |
| Country | France |
| Start | |
| Description | CAPITALs Programme grant, EP/J017566/1 |
| Amount | £5,900,000 (GBP) |
| Funding ID | EP/J017566/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2012 |
| End | 05/2017 |
| Description | CASE studentship |
| Amount | £80,000 (GBP) |
| Organisation | Procter & Gamble |
| Sector | Private |
| Country | United States |
| Start | |
| Description | Creativity@home-Novel Tools for Single Cell Manipulation |
| Amount | £101,750 (GBP) |
| Funding ID | EP/I031561/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | EU Multi-ITN: 'Smart Nano-objects for Alteration of Lipid Bilayers' (Project acronym: SNAL); |
| Amount | £250,000 (GBP) |
| Funding ID | 608184 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 04/2014 |
| End | 03/2018 |
| Description | Elements of a Vesicle Machine |
| Amount | £201,409 (GBP) |
| Funding ID | EP/H024425/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Frontier Manufacturing: Scaling up synthetic biology |
| Amount | £5,158,504 (GBP) |
| Funding ID | EP/K038648/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Initial Training Networks grant for Next Generation AgriChem. |
| Amount | £2,500,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Institute of Chemical Biology, Centre for Doctoral Training |
| Amount | £1,000,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Membrane Translocation Initiative |
| Amount | £115,000 (GBP) |
| Organisation | Procter & Gamble |
| Sector | Private |
| Country | United States |
| Start | |
| Description | Membrane Translocation Initiative |
| Amount | £115,000 (GBP) |
| Organisation | Procter & Gamble |
| Sector | Private |
| Country | United States |
| Start | |
| Description | Membrane proteins and immune evasion, BBSRC (DTP) |
| Amount | £90,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2013 |
| End | 09/2017 |
| Description | Molecular imaging using ultrasound |
| Amount | £716,105 (GBP) |
| Funding ID | EP/G038163/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Next Generation Analytical Tools: Application to Protein Oxidations that affect Human Health and Wellbeing, EP/I017887/1 |
| Amount | £3,885,167 (GBP) |
| Funding ID | EP/I017887/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Nuffield Bursary Scheme |
| Amount | £2,000 (GBP) |
| Organisation | Nuffield Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Optical Control of Emulsion Drops for Nanofluidics and Microfabrication |
| Amount | £505,226 (GBP) |
| Funding ID | EP/I013342/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Pathways to Impact Funding |
| Amount | £74,429 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Pathways to Impact: Hybrid Self-sustaining Microscale Machinery, IC/EPSRC |
| Amount | £75,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Pathways to Impact: New Analytical Tools for Personalized Healthcare and Portable Separation Science, IC/EPSRC |
| Amount | £75,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2010 |
| End | 06/2011 |
| Description | PhD Studentship (Membrane Protein Folding), Pfizer plc |
| Amount | £46,000 (GBP) |
| Organisation | Pfizer Ltd |
| Sector | Private |
| Country | United Kingdom |
| Start | |
| Description | PhD Studentship (Membrane Protein Folding), Pfizer plc |
| Amount | £46,000 (GBP) |
| Organisation | Pfizer Ltd |
| Sector | Private |
| Country | United Kingdom |
| Start | |
| Description | Studies of membrane mediated protein-protein communication, BBSRC (DTP) |
| Amount | £90,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2013 |
| End | 09/2017 |
| Description | Synchr beam time , SC 3134 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time , SC 3134 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time : Membrane homeostasis, SC 2799 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time : Membrane homeostasis, SC 2799 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time, SC 3266 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time, SC 3266 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time: 3-D hexagonal phase, SC 2800 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time: 3-D hexagonal phase, SC 2800 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time: Bridging the divide between lyotropic phase transitions in model membranes and ex-vivo systems, SC 2904 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time: Bridging the divide between lyotropic phase transitions in model membranes and ex-vivo systems, SC 2904 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time: Patterned cubics, SC 3664 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time: Patterned cubics, SC 3664 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time: Swollen cubics, SC 3495 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Synchr beam time: Swollen cubics, SC 3495 |
| Amount | £30,000 (GBP) |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | |
| Description | Three Studentships (Non-Specific Binding Initiative), GSK plc |
| Amount | £133,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | |
| Description | Three Studentships (Non-Specific Binding Initiative), GSK plc |
| Amount | £133,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 10/2006 |
| End | 09/2010 |
| Description | Tsinghua University Exchange Programme, IC/EPSRC |
| Amount | £45,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Two Non-Specific Binding Studentships, GSK plc |
| Amount | £147,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | |
| Description | Two Non-Specific Binding Studentships, GSK plc |
| Amount | £147,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 10/2008 |
| End | 09/2013 |
| Description | Scientific Collaboration |
| Organisation | Cancer Research UK |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Collaboration with Peter Parker on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Commonwealth Scientific and Industrial Research Organisation |
| Country | Australia |
| Sector | Public |
| PI Contribution | Collaboration with Irena Krodkiewska on "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids in Water" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Commonwealth Scientific and Industrial Research Organisation |
| Country | Australia |
| Sector | Public |
| PI Contribution | Collaboration with Sharon M. Sagnella on "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids in Water" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Commonwealth Scientific and Industrial Research Organisation |
| Country | Australia |
| Sector | Public |
| PI Contribution | Collaboration with Calum J. Drummond on "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids in Water" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Commonwealth Scientific and Industrial Research Organisation |
| Country | Australia |
| Sector | Public |
| PI Contribution | Collaboration with Minoo Moghaddam on "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids in Water" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Commonwealth Scientific and Industrial Research Organisation |
| Country | Australia |
| Sector | Public |
| PI Contribution | Collaboration with Charlotte E. Conn on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides", "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Diamond Light Source |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Collaboration with Adam J Kowalski on "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Diamond Light Source |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Collaboration with Nick J. Terrill on "Hydrostatic Pressure Effects on the Lamellar to Gyroid Cubic Phase Transition of Monolinolein at Limited Hydration", "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | ETH Zurich |
| Department | Department of Chemistry and Applied Biosciences |
| Country | Switzerland |
| Sector | Academic/University |
| PI Contribution | Collaboration with Andrew J. deMello on "Novel technologies for the formation of 2-D and 3-D droplet interface bilayer networks" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | European Synchrotron Radiation Facility |
| Country | France |
| Sector | Charity/Non Profit |
| PI Contribution | Collaboration with Michael Sztucki on "A lyotropic inverse ribbon phase in a branched-chain polyoxyethylene surfactant: pressure effects" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Doryen Bubeck on "Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59" |
| Start Year | 2012 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Miroslava Novakova on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Paul F Luckham on "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Andrew J. Heron on "A high pressure cell for simultaneous osmotic pressure and x-ray diffraction measurements " |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with C. E. Stanley on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Tsing-Young Tang on "Engineering bicontinuous cubic structures at the nanoscale?the role of chain splay" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Laura M. C. Barter on "Engineering de Novo Membrane-Mediated Protein?Protein Communication Networks" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Paul S. Freemont on "Design of a prototype flow microreactor for synthetic biology in vitro" |
| Start Year | 2012 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Sophia Yaliraki on Modelling membrane binding |
| Start Year | 2012 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Ian Gould on Drug-lipid interactions |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Teresa Peiró-Salvador on "Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with X. Z. Niu on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with João T Cabral on "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Hazel P Martin on "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with J. B. Edel on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with B. Zhang on "Droplet-based compartmentalization of chemically separated components in two-dimensional separations" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Emilie Macé on "Molecular Dynamics Simulations of Liquid Condensed to Liquid Expanded Transitions in DPPC Monolayers" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Martin Buck on PspA - membrane interactions |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with K. S. Elvira on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Fernando Bresme on "Molecular Dynamics Simulations of Liquid Condensed to Liquid Expanded Transitions in DPPC Monolayers" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Christian R. Boehm on "Design of a prototype flow microreactor for synthetic biology in vitro" |
| Start Year | 2012 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Paul French on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Edward W. Tate on "Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Piers R. J. Gaffney on "Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Rüdiger Woscholski on "Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate", "Engineering de Novo Membrane-Mediated Protein?Protein Communication Networks" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with James A. Clarkeon on "Pressure?temperature phase behaviour of natural sphingomyelin extracts" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with David Klug on "Droplet-based compartmentalization of chemically separated components in two-dimensional separations" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Duncan Casey on "Drug interactions with lipid membranes" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Ali Salehi-Reyhani on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with A. D. Gee on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation" and "Drug interactions with lipid membranes" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Hairul A.A. Hamid on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Edward Burgin on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with R. T. Marszalek on "Droplet-based compartmentalization of chemically separated components in two-dimensional separations" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Nick Long on PET ligand synthesis |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Joseph Kaplinsky on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Dan Davis on Membrane organisation at the synapse |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Mark A. A. Neil on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Annela M. Seddonon "Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale", "Drug interactions with lipid membranes", Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate, "Engineering bicontin |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Xiaodong Zhang on PspA - membrane interactions |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | Institute of Cancer Research UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Keith R. Willison on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Cécile A. Dreiss on "Assembling and de-assembling micelles: competitive interactions of cyclodextrins and drugs with Pluronics" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Rong Liu on "Assembling and de-assembling micelles: competitive interactions of cyclodextrins and drugs with Pluronics" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Richard A.G. Smith on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Ekene Nwabunwanne on "Assembling and de-assembling micelles: competitive interactions of cyclodextrins and drugs with Pluronics" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Max Planck Society |
| Department | Max Planck Institute of Colloids and Interfaces |
| Country | Germany |
| Sector | Charity/Non Profit |
| PI Contribution | Collaboration with Rumiana Dimova on Membrane fusion |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Polytechnic University of Valencia |
| Country | Spain |
| Sector | Academic/University |
| PI Contribution | Collaboration with Alfonso Martínez-Felipe on "Non-symmetric liquid crystal dimer containing a carbohydrate-based moiety" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Rutherford Appleton Laboratory |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Sarah E. Rogers on "Automated high pressure cell for pressure jump x-ray diffraction" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Shiraz University of Technology |
| Country | Iran, Islamic Republic of |
| Sector | Academic/University |
| PI Contribution | Collaboration with Delara Mohammad-Aghaie on "Molecular Dynamics Simulations of Liquid Condensed to Liquid Expanded Transitions in DPPC Monolayers" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | Technical University of Dortmund |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Collaboration with Christoph Jeworrek on "Hydrostatic Pressure Effects on the Lamellar to Gyroid Cubic Phase Transition of Monolinolein at Limited Hydration" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Technical University of Dortmund |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Collaboration with Roland Winter on "Hydrostatic Pressure Effects on the Lamellar to Gyroid Cubic Phase Transition of Monolinolein at Limited Hydration" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | Unilever |
| Department | Unilever Research and Development |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Collaboration with Laurent Soubiran on "Factors Controlling the Stability of a Kinetically Hindered Lamellar_Lamellar Transition", "The lyotropic phase behaviour of ester quaternary surfactants" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Unilever |
| Department | Unilever Research and Development |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Collaboration with John Hubbard on "Factors Controlling the Stability of a Kinetically Hindered Lamellar_Lamellar Transition", "The lyotropic phase behaviour of ester quaternary surfactants" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | Unilever |
| Department | Unilever Research and Development |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Collaboration with Stephane Ugazio on "Factors Controlling the Stability of a Kinetically Hindered Lamellar_Lamellar Transition", "The lyotropic phase behaviour of ester quaternary surfactants" |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | University Paris Sud |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Collaboration with H. Delacroix on "Hydrostatic pressure effects on a hydrated lipid inverse micellar Fd3m cubic phase" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | University of Aberdeen |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Corrie T. Imrie on "Non-symmetric liquid crystal dimer containing a carbohydrate-based moiety" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | University of Aberdeen |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Andrew G. Cook on "Non-symmetric liquid crystal dimer containing a carbohydrate-based moiety" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | University of Aberdeen |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with James L. Wardell on "Non-symmetric liquid crystal dimer containing a carbohydrate-based moiety" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Paula J. Booth on "Engineering de Novo Membrane-Mediated Protein?Protein Communication Networks" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Annela M. Seddonon "Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale", "Drug interactions with lipid membranes", Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate, "Engineering bicontin |
| Start Year | 2008 |
| Description | Scientific Collaboration |
| Organisation | University of Malaya |
| Country | Malaysia |
| Sector | Academic/University |
| PI Contribution | Collaboration with Rauzah Hashim on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | University of Malaya |
| Country | Malaysia |
| Sector | Academic/University |
| PI Contribution | Collaboration with Thorsten Heidelberg on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | University of Malaya |
| Country | Malaysia |
| Sector | Academic/University |
| PI Contribution | Collaboration with Seyed M. Mirzadeh Husseini on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | University of Malaya |
| Country | Malaysia |
| Sector | Academic/University |
| PI Contribution | Collaboration with N. Idayu Zahid on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | University of Malaya |
| Country | Malaysia |
| Sector | Academic/University |
| PI Contribution | Collaboration with Syahila Duali Hussen on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Gordon J. T. Tiddy on "A lyotropic inverse ribbon phase in a branched-chain polyoxyethylene surfactant: pressure effects" |
| Start Year | 2010 |
| Description | Scientific Collaboration |
| Organisation | University of Nottingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Paul O'Shea |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Steven Johnson on "Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59" |
| Start Year | 2012 |
| Description | Scientific Collaboration |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Susan M. Lea on "Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59" |
| Start Year | 2012 |
| Description | Scientific Collaboration |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Syma Khalid on "DNA Lipoplexes: Formation of the Inverse Hexagonal Phase Observed by Coarse-Grained Molecular Dynamics Simulation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Josephine Corsi on "DNA Lipoplexes: Formation of the Inverse Hexagonal Phase Observed by Coarse-Grained Molecular Dynamics Simulation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with George S. Attard on "DNA Lipoplexes: Formation of the Inverse Hexagonal Phase Observed by Coarse-Grained Molecular Dynamics Simulation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Robert W. Hawtin on "DNA Lipoplexes: Formation of the Inverse Hexagonal Phase Observed by Coarse-Grained Molecular Dynamics Simulation" |
| Start Year | 2009 |
| Description | Scientific Collaboration |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Xize Niu on "Novel technologies for the formation of 2-D and 3-D droplet interface bilayer networks" |
| Start Year | 2011 |
| Description | Scientific Collaboration |
| Organisation | University of Warwick |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Nigel Burroughs on Modelling the immune synapse |
| Start Year | 2011 |
| Description | Visiting Professor |
| Organisation | University of Malaya |
| Department | Physics Department |
| Country | Malaysia |
| Sector | Academic/University |
| PI Contribution | 12 lectures on ?Lyotropic Liquid Crystals and X-ray Diffraction? |
| Start Year | 2011 |
| Description | CECAM Workshop |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Workshop entitled "Multi scale approaches to nano-structured soft matter: from amphiphiles to block copolymers". |
| Year(s) Of Engagement Activity | 2018 |
| Description | Chair |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | ISIS Facility Board, STFC |
| Year(s) Of Engagement Activity | 2015,2016 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Public engagement talk. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Invited Lecture, Distinguished Faculty. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Editorial Advisory Panel. |
| Year(s) Of Engagement Activity | 2011 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Non-Executive Board Member, ICON (2005 - 2013). |
| Year(s) Of Engagement Activity | Pre-2006,2006 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Editorial Board. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Invited talk at DSM plc in Holland on the ICB. |
| Year(s) Of Engagement Activity | 2011 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The Festival was formulated as a chance to bring the CDTs together and discuss the future of science and the importance of CDTs. |
| Year(s) Of Engagement Activity | 2012 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | Industry / academia engagement talk arranged by RSC / British FCO at National Chemical Laboratories. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Organised the London Schools Chemistry Challenge, a competition designed to commemorate the International Year of Chemistry that was open to all students studying Chemistry (GCSE or A-level) in secondary schools in Greater London. Entries could take the form of a poster, model, booklet, video presentation-the choice was left to the students. The competition was an overwhelming success with 1300 students registering to take part from 250 schools across London. |
| Year(s) Of Engagement Activity | 2012 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Editorial Board of the Royal Society's Journal "Interface" (2004 - 2011). |
| Year(s) Of Engagement Activity | Pre-2006,2006 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Invited Lecture: "DNA double helices recognize mutual sequence homology in a protein free environment". |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Paper has been identified as a 'hot article' for Soft Matter. |
| Year(s) Of Engagement Activity | 2011 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Invited Lecture. Symposia were showcasing various aspects of collaboration across different geographic regions or between different sectors of chemical research (industry, academia, research institutes, government laboratories). Symposia were focusing on partnerships between traditional industries and contract research organizations (CROs) or contract manufacturing organizations (CMO's). Other collaborative arrangements of interest included precompetitive industrial collaborations on enabling chemical technologies, new technologies and new strategies for facilitating effective collaborations across multiple time zones, and managing intellectual property and licensing. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | In collaboration with Medi-mation produced series of short movies to showcase engineering principles behind EPSRC funded work looking at the development of artificial cells. |
| Year(s) Of Engagement Activity | 2012 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Invited Lecture. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Chair of Chemistry panel June 2009 - EPSR. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Organiser of Chemistry Stand at Imperial Festival. Imperial Festival is a brand new annual celebration that showcase to the public the myriad accomplishments and activities of staff and students at Imperial. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Guest Editor. Comissioned to put together a special issue on Single Cell Analysis for Biomicrofluidics (with Andrew de Mello). |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Featured on ESRF homepage as a 'Spotlight on Science'. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Invited Lecture. High pressure research is a fast growing discipline, yielding interesting and exciting results in many fields of science, technology and biotechnology. |
| Year(s) Of Engagement Activity | 2011 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | Invited Lecture. This represented the first joint ILL and ESRF user meeting. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Invited Lecture. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Member of the Editorial Board of Biochimica Biophysica Acta (Jan 2000 - present). |
| Year(s) Of Engagement Activity | Pre-2006,2006 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Attended play on creation of mauveine and roseine and unveiled plaque at Victory PLace Primary school. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Invited talk at the RSC "Top of the Class". |
| Year(s) Of Engagement Activity | 2011 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | European Network of Excellence for Biophotonics feature article on Nanoblobs. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Plenary Lecture. The ESRF Users' Meeting gave ESRF Users the opportunity to discuss the most recent advances in science using synchrotron radiation and also, exceptionally this year, to participate in lively discussions about the future of ESRF and how it could be used to solve some of today's biggest challenges in science. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Invited Front Cover-Chem Soc Rev ( £500, cover art charge ). |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Member of the Editorial Board of Current Opinion in Colloid and Interface Science (Jan 1995 - present). |
| Year(s) Of Engagement Activity | Pre-2006,2006 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Invited Lecture. |
| Year(s) Of Engagement Activity | 2012 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Invited Front Cover. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Member of the Editorial Board (Chemistry Subcommittee). |
| Year(s) Of Engagement Activity | 2013 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | RSC Chemical Biology Highlights Article. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Undergraduate students |
| Results and Impact | Organised off-site visits for undergraduate students (2010). Took 3rd years to Diamond Light Source to give them experience of large scale research facilities. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Schools talk at Peter Symonds College. |
| Year(s) Of Engagement Activity | 2012 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Highlight feature on International Liquid Crystal Society website (Figure provided by Gemma Shearman). |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Organised off-site visits for undergraduate students (2009). Took 3rd years to Diamond Light Source to give them experience of large scale research facilities. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Member, Editorial Board. |
| Year(s) Of Engagement Activity | 2012 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Member of the Editorial Advisory Board (Chemistry Subcommittee) of Imperial College Press (May 2003 - present). |
| Year(s) Of Engagement Activity | 2009 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Organiser of Chemistry Stand at Imperial Festival. Imperial Festival is a brand new annual celebration that showcase to the public the myriad accomplishments and activities of staff and students at Imperial. |
| Year(s) Of Engagement Activity | 2012 |
| Description | Development of submillimetre bolometer array and wafer bonding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Invited talk at DSM plc to DSM Board/Research Strategy Team (on SCP project). |
| Year(s) Of Engagement Activity | 2011 |
| Description | Invited Lecture - 18th International Biophysics Congress, Brisbane, 2rd - 7th August 2014. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | 18th International Biophysics Congress, Brisbane, 2rd - 7th August 2014. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Physical Sciences Strategic Advisory Board - EPSRC (2008-2011) |
| Year(s) Of Engagement Activity | 2008,2009,2010,2011 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | EPSRC Career Acceleration and Leadership Fellowships Panel (9th December 2009) |
| Year(s) Of Engagement Activity | 2009 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Joint ISIS Instrument Beam Managemant Group member (IBM 5; Spectroscopy) |
| Year(s) Of Engagement Activity | 2015,2016 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | RSC Faraday Division Awards Panel for 2013 |
| Year(s) Of Engagement Activity | 2013 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | EPSRC Career Acceleration and Leadership Fellowships Panel (9th November 2010) |
| Year(s) Of Engagement Activity | 2010 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Committee member, British Biophysical Society (2001 - present) |
| Year(s) Of Engagement Activity | Pre-2006,2006,2007,2008,2009,2010,2011,2012,2013,2014,2015,2016 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Faraday Division Council Member (2009 - 2012) |
| Year(s) Of Engagement Activity | 2009,2010,2011,2012 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | EPSRC Panel: Materials (12th February 2009) |
| Year(s) Of Engagement Activity | 2009 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Diamond Synchrotron Beamline I22 Working Group (June 2006 -present) |
| Year(s) Of Engagement Activity | 2006,2007,2008,2009,2010,2011,2012,2013,2014,2015,2016 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | EPSRC College: Structure, Bonding and Reaction Mechanism (January 2006 - present) |
| Year(s) Of Engagement Activity | Pre-2006,2006,2007,2008,2009,2010,2011,2012,2013,2014,2015,2016 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Physical Chemistry Chemical Physics (PCCP) Ownership Board - one of 2 UK representatives (2012 - ) |
| Year(s) Of Engagement Activity | 2012,2013,2014,2015,2016 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | American Biophysical Society |
| Year(s) Of Engagement Activity | 2015,2016 |
| Description | Member |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Member, Scientific Unions Committee of Royal Society (2004 - present) |
| Year(s) Of Engagement Activity | Pre-2006,2006,2007,2008,2009,2010,2011,2012,2013,2014,2015,2016 |
| Description | Membership of guideline committee |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Roving Panel Member, EPSRC Physical Sciences Meeting (25th - 26th Sept 2012) |
| Year(s) Of Engagement Activity | 2012 |
| Description | Membership of guideline committee |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | RSC Council representing Faraday Division (7th July 2010) |
| Year(s) Of Engagement Activity | 2010 |
| Description | Panel Chair |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Panel Chair for the evaluation of the Danish Centre for Insoluble Protein Structures (2009). |
| Year(s) Of Engagement Activity | 2009 |
| Description | Reviewer |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | External Reviewer for University of Manchester School of Chemistry REF Preparation Exercise (2012) |
| Year(s) Of Engagement Activity | 2012 |
| Description | Reviewer |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Beamline ID02 Review Panel, European Synchrotron Radiation Facility (ESRF), Grenoble, 24th - 25th May 2011 |
| Year(s) Of Engagement Activity | 2011 |
| Description | Reviewer |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Assessor of research outputs, Dept of Applied Mathematics, Australian National University, Canberra (2010) |
| Year(s) Of Engagement Activity | 2010 |
| Description | Secretary |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | British Biophysical Society (2008 - 2011) |
| Year(s) Of Engagement Activity | 2008,2009,2010,2011 |
| Description | Secretary |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | European Biophysical Societies' Association, (2013 - present) |
| Year(s) Of Engagement Activity | 2013,2014,2015,2016 |