Nanoparticles for the Targeted Delivery of Therapeutic Agents to the Brain for the Treatment of Dementias.

Lead Research Organisation: North Bristol NHS Trust
Department Name: Directorate of Neurosciences

Abstract

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Publications

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Barua NU (2013) Intermittent convection-enhanced delivery to the brain through a novel transcutaneous bone-anchored port. in Journal of neuroscience methods

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Barua NU (2012) Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model. in Fluids and barriers of the CNS

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Barua NU (2014) Convection-enhanced drug delivery to the brain: therapeutic potential and neuropathological considerations. in Brain pathology (Zurich, Switzerland)

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Barua NU (2012) Convection-enhanced delivery of neprilysin: a novel amyloid-ß-degrading therapeutic strategy. in Journal of Alzheimer's disease : JAD

 
Description Excellent data gathered in order to progress Convection enhanced delivery for neuroscience
Exploitation Route Has led to future grant applications
Sectors Healthcare
 
Description The work undertaken on this award, has enhanced our research. We have published and continued working with the collaborators
Sector Healthcare
Impact Types Societal
 
Description University of Bath 
Organisation University of Bath
Department Department of Chemistry
Country United Kingdom 
Sector Academic/University 
PI Contribution MRC grant subcontract to supply /formulate nanocomplexes
Collaborator Contribution Chemical knowledge in formulation of nanoparticles
Impact Ongoing reached milesone one at present, now onwards to the next milestone
Start Year 2011