Rapid Multiplexed Electronic Detection of Biomarkers for Point-of-Care Diagnostics (eTect)
Lead Research Organisation:
University of Leeds
Department Name: Electronic and Electrical Engineering
Abstract
The applicants have developed a novel technology based on low-cost semiconductor and molecular technologies that is able to detect minute protein traces, enabling rapid in-vitro detection of multiple biomarkers, including disease biomarkers, at low cost and without the need for complicated assays. This disruptive technology has the potential to impact upon a number of large, growing markets. Our technology offers easy-to-use, multiplexed electronic detection of biomarkers and has the potential to be used in hundreds, if not thousands, of diagnostic applications in multiple sectors including healthcare, veterinary, drug development, security and agrotech. More information is available on our website www.etect.co.uk.
Publications
Johnson S
(2012)
Redox-induced conformational change in mercaptoalkanoic acid multilayer films.
in Langmuir : the ACS journal of surfaces and colloids
Raina M
(2015)
Antibody mimetic receptor proteins for label-free biosensors.
in The Analyst
Sharma R
(2016)
Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity.
in Biosensors & bioelectronics
Zaccari I
(2014)
Improving the dielectric properties of ethylene-glycol alkanethiol self-assembled monolayers.
in Langmuir : the ACS journal of surfaces and colloids
| Description | This grant funded the translation of a previously developed electronic protein biosensor technology into a commercial product. As part of this grant, the biosensor technology was integrated into the commercial partner's existing in vitro diagnostic platform. |
| Exploitation Route | The findings of this grant were taken forward through a number of routes (including the WT/EPSRC funded WELMEC Centre in Medical Engineering) and the technology has now been commercialised via a venture-captial funded University of Leeds spin-out (Relitect Ltd). |
| Sectors | Healthcare |
| URL | http://www.relitect.com |
| Description | An electronic, multiplexed, label-free protein sensor technology for clinical diagnostics was further developed. High-sensitivity, reproducible detection of clinically relevant protein biomarkers was demonstrated in full serum through an electrochemical impedance phase-change upon antibody(mimetic)-biomarker binding. The University's venture capital partner IP Group is currently appraising the technology for a university spin-out. |
| First Year Of Impact | 2011 |
| Sector | Healthcare |
| Impact Types | Economic |
| Description | University of Leeds |
| Amount | £67,378 (GBP) |
| Funding ID | Multiplexed Electronic Detection of Biomarkers |
| Organisation | University of Leeds |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2011 |
| End | 02/2012 |
| Company Name | Relitect Ltd |
| Description | The company develops biosensor technology for in vitro diagnostic applications. The technology is based on technology developed at the University of Leeds. |
| Year Established | 2014 |
| Impact | The company was only established recently, and is currently developing a product. Hence no impact can be reported yet. |
| Website | http://www.relitect.com |